메뉴 건너뛰기




Volumn 31, Issue 5, 2012, Pages 1253-1265

Genetic evidence of a redox-dependent systemic wound response via Hayan protease-phenoloxidase system in Drosophila

Author keywords

Drosophila innate immunity; Hayan serine protease; pro phenoloxidase; reactive oxygen species; wound response

Indexed keywords

MELANIN; MONOPHENOL MONOOXYGENASE; PROTEIN HAYAN; SERINE PROTEINASE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 84863281623     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.476     Document Type: Article
Times cited : (97)

References (60)
  • 1
    • 0025652684 scopus 로고
    • The prophenoloxidase cascade in insect immunity
    • Ashida M (1990) The prophenoloxidase cascade in insect immunity. Res Immunol 141: 908-910
    • (1990) Res Immunol , vol.141 , pp. 908-910
    • Ashida, M.1
  • 2
    • 0014149056 scopus 로고
    • Activation of pre-phenol oxidase in hemolymph of the silkworm, Bombyx mori
    • Ashida M, Ohnishi E (1967) Activation of pre-phenol oxidase in hemolymph of the silkworm, Bombyx mori. Arch Biochem Biophys 122: 411-416
    • (1967) Arch Biochem Biophys , vol.122 , pp. 411-416
    • Ashida, M.1    Ohnishi, E.2
  • 3
    • 0001261788 scopus 로고
    • Biochemistry of the prophenoloxidase
    • Ohnishi E, Ishizaki I (eds), Tokyo/Springer Verlag, Berlin: Japan Science Society Press
    • Ashida M, Yamazaki HI (1990) Biochemistry of the prophenoloxidase. In Insects: With Special Reference to Its Activation, Ohnishi E, Ishizaki I (eds), pp 239-265. Tokyo/Springer Verlag, Berlin: Japan Science Society Press
    • (1990) Insects: With Special Reference to Its Activation , pp. 239-265
    • Ashida, M.1    Yamazaki, H.I.2
  • 4
    • 77950612276 scopus 로고    scopus 로고
    • A signaling protease required for melanization in Drosophila affects resistance and tolerance of infections
    • Ayres JS, Schneider DS (2008) A signaling protease required for melanization in Drosophila affects resistance and tolerance of infections. PLoS Biol 6: 2764-2773
    • (2008) PLoS Biol , vol.6 , pp. 2764-2773
    • Ayres, J.S.1    Schneider, D.S.2
  • 5
    • 67349162782 scopus 로고    scopus 로고
    • Cytokine signaling mediates UV-induced nociceptive sensitization in Drosophila larvae
    • Babcock DT, Landry C, Galko MJ (2009) Cytokine signaling mediates UV-induced nociceptive sensitization in Drosophila larvae. Curr Biol 19: 799-806
    • (2009) Curr Biol , vol.19 , pp. 799-806
    • Babcock, D.T.1    Landry, C.2    Galko, M.J.3
  • 6
    • 77953423860 scopus 로고    scopus 로고
    • Activation of insect phenoloxidase after injury: Endogenous versus foreign elicitors
    • Bidla G, Hauling T, Dushay MS, Theopold U (2009) Activation of insect phenoloxidase after injury: endogenous versus foreign elicitors. J Innate Immun 1: 301-308
    • (2009) J Innate Immun , vol.1 , pp. 301-308
    • Bidla, G.1    Hauling, T.2    Dushay, M.S.3    Theopold, U.4
  • 7
    • 74249110769 scopus 로고    scopus 로고
    • Genetic screen in Drosophila melanogaster uncovers a novel set of genes required for embryonic epithelial repair
    • Campos I, Geiger JA, Santos AC, Carlos V, Jacinto A (2010) Genetic screen in Drosophila melanogaster uncovers a novel set of genes required for embryonic epithelial repair. Genetics 184: 129-140
    • (2010) Genetics , vol.184 , pp. 129-140
    • Campos, I.1    Geiger, J.A.2    Santos, A.C.3    Carlos, V.4    Jacinto, A.5
  • 8
    • 44649197623 scopus 로고    scopus 로고
    • The proPO-system: Pros and cons for its role in invertebrate immunity
    • Cerenius L, Lee BL, Soderhall K (2008) The proPO-system: pros and cons for its role in invertebrate immunity. Trends Immunol 29: 263-271
    • (2008) Trends Immunol , vol.29 , pp. 263-271
    • Cerenius, L.1    Lee, B.L.2    Soderhall, K.3
  • 10
    • 0037013856 scopus 로고    scopus 로고
    • The Toll and Imd pathways are the major regulators of the immune response in Drosophila
    • DOI 10.1093/emboj/21.11.2568
    • De Gregorio E, Spellman PT, Tzou P, Rubin GM, Lemaitre B (2002b) The Toll and Imd pathways are the major regulators of the immune response in Drosophila. EMBO J 21: 2568-2579 (Pubitemid 34619373)
    • (2002) EMBO Journal , vol.21 , Issue.11 , pp. 2568-2579
    • De Gregorio, E.1    Spellman, P.T.2    Tzou, P.3    Rubin, G.M.4    Lemaitre, B.5
  • 12
    • 52549093726 scopus 로고    scopus 로고
    • Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll
    • El Chamy L, Leclerc V, Caldelari I, Reichhart JM (2008) Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll. Nat Immunol 9: 1165-1170
    • (2008) Nat Immunol , vol.9 , pp. 1165-1170
    • El Chamy, L.1    Leclerc, V.2    Caldelari, I.3    Reichhart, J.M.4
  • 13
    • 0343851622 scopus 로고    scopus 로고
    • Systemic responses to trauma
    • Foex BA (1999) Systemic responses to trauma. Br Med Bull 55: 726-743
    • (1999) Br Med Bull , vol.55 , pp. 726-743
    • Foex, B.A.1
  • 14
    • 19344365657 scopus 로고    scopus 로고
    • Cellular and genetic analysis of wound healing in Drosophila larvae
    • Galko MJ, Krasnow MA (2004) Cellular and genetic analysis of wound healing in Drosophila larvae. PLoS Biol 2: E239
    • (2004) PLoS Biol , vol.2
    • Galko, M.J.1    Krasnow, M.A.2
  • 15
    • 11244343895 scopus 로고    scopus 로고
    • An antioxidant system required for host protection against gut infection in Drosophila
    • DOI 10.1016/j.devcel.2004.11.007, PII S1534580704004058
    • Ha EM, Oh CT, Ryu JH, Bae YS, Kang SW, Jang IH, Brey PT, Lee WJ (2005) An antioxidant system required for host protection against gut infection in Drosophila. Dev Cell 8: 125-132 (Pubitemid 40058012)
    • (2005) Developmental Cell , vol.8 , Issue.1 , pp. 125-132
    • Ha, E.-M.1    Oh, C.-T.2    Ryu, J.-H.3    Bae, Y.-S.4    Kang, S.-W.5    Jang, I.-H.6    Brey, P.T.7    Lee, W.-J.8
  • 16
    • 79551610653 scopus 로고    scopus 로고
    • Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila
    • Hochmuth CE, Biteau B, Bohmann D, Jasper H (2011) Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila. Cell Stem Cell 8: 188-199
    • (2011) Cell Stem Cell , vol.8 , pp. 188-199
    • Hochmuth, C.E.1    Biteau, B.2    Bohmann, D.3    Jasper, H.4
  • 18
    • 40549103093 scopus 로고    scopus 로고
    • CLIP-domain serine proteases in Drosophila innate immunity
    • Jang IH, Nam HJ, Lee WJ (2008) CLIP-domain serine proteases in Drosophila innate immunity. BMB Rep 41: 102-107
    • (2008) BMB Rep , vol.41 , pp. 102-107
    • Jang, I.H.1    Nam, H.J.2    Lee, W.J.3
  • 19
    • 14844327760 scopus 로고    scopus 로고
    • Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
    • DOI 10.1016/j.cell.2004.12.041
    • Kamata H, Honda S, Maeda S, Chang L, Hirata H, Karin M (2005) Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120: 649-661 (Pubitemid 40343077)
    • (2005) Cell , vol.120 , Issue.5 , pp. 649-661
    • Kamata, H.1    Honda, S.-I.2    Maeda, S.3    Chang, L.4    Hirata, H.5    Karin, M.6
  • 20
    • 33646037067 scopus 로고    scopus 로고
    • Drosophila immunity: A largescale in vivo RNAi screen identifies five serine proteases required for Toll activation
    • Kambris Z, Brun S, Jang IH, Nam HJ, Romeo Y, Takahashi K, Lee WJ, Ueda R, Lemaitre B (2006) Drosophila immunity: a largescale in vivo RNAi screen identifies five serine proteases required for Toll activation. Curr Biol 16: 808-813
    • (2006) Curr Biol , vol.16 , pp. 808-813
    • Kambris, Z.1    Brun, S.2    Jang, I.H.3    Nam, H.J.4    Romeo, Y.5    Takahashi, K.6    Lee, W.J.7    Ueda, R.8    Lemaitre, B.9
  • 21
    • 0032992544 scopus 로고    scopus 로고
    • Serine proteinase inhibitors in arthropod immunity
    • Kanost MR (1999) Serine proteinase inhibitors in arthropod immunity. Dev Comp Immunol 23: 291-301
    • (1999) Dev Comp Immunol , vol.23 , pp. 291-301
    • Kanost, M.R.1
  • 22
    • 1642504737 scopus 로고    scopus 로고
    • Innate immune responses of a lepidopteran insect, Manduca sexta
    • DOI 10.1111/j.0105-2896.2004.0121.x
    • Kanost MR, Jiang H, Yu XQ (2004) Innate immune responses of a lepidopteran insect, Manduca sexta. Immunol Rev 198: 97-105 (Pubitemid 38406938)
    • (2004) Immunological Reviews , vol.198 , pp. 97-105
    • Kanost, M.R.1    Jiang, H.2    Yu, X.-Q.3
  • 23
    • 0034693324 scopus 로고    scopus 로고
    • Gram-negative bacteria-binding protein, a pattern recognition receptor for lipopolysaccharide and beta-1,3-glucan that mediates the signaling for the induction of innate immune genes in Drosophila melanogaster cells
    • Kim YS, Ryu JH, Han SJ, Choi KH, Nam KB, Jang IH, Lemaitre B, Brey PT, Lee WJ (2000) Gram-negative bacteria-binding protein, a pattern recognition receptor for lipopolysaccharide and beta-1,3-glucan that mediates the signaling for the induction of innate immune genes in Drosophila melanogaster cells. J Biol Chem 275: 32721-32727
    • (2000) J Biol Chem , vol.275 , pp. 32721-32727
    • Kim, Y.S.1    Ryu, J.H.2    Han, S.J.3    Choi, K.H.4    Nam, K.B.5    Jang, I.H.6    Lemaitre, B.7    Brey, P.T.8    Lee, W.J.9
  • 24
    • 22144451864 scopus 로고    scopus 로고
    • Superoxide and hydrogen peroxide formation during enzymatic oxidation of DOPA by phenoloxidase
    • DOI 10.1080/10715760500166693
    • Komarov DA, Slepneva IA, Glupov VV, Khramtsov VV (2005) Superoxide and hydrogen peroxide formation during enzymatic oxidation of DOPA by phenoloxidase. Free Radic Res 39: 853-858 (Pubitemid 40975078)
    • (2005) Free Radical Research , vol.39 , Issue.8 , pp. 853-858
    • Komarov, D.A.1    Slepneva, I.A.2    Glupov, V.V.3    Khramtsov, V.V.4
  • 26
    • 36549019937 scopus 로고    scopus 로고
    • Systemic inflammation after trauma
    • DOI 10.1016/j.injury.2007.10.003, PII S0020138307004184, Immune Response to Trauma
    • Lenz A, Franklin GA, Cheadle WG (2007) Systemic inflammation after trauma. Injury 38: 1336-1345 (Pubitemid 350192404)
    • (2007) Injury , vol.38 , Issue.12 , pp. 1336-1345
    • Lenz, A.1    Franklin, G.A.2    Cheadle, W.G.3
  • 27
    • 78951472621 scopus 로고    scopus 로고
    • A targeted UAS-RNAi screen in Drosophila larvae identifies wound closure genes regulating distinct cellular processes
    • Lesch C, Jo J, Wu Y, Fish GS, Galko MJ (2010) A targeted UAS-RNAi screen in Drosophila larvae identifies wound closure genes regulating distinct cellular processes. Genetics 186: 943-957
    • (2010) Genetics , vol.186 , pp. 943-957
    • Lesch, C.1    Jo, J.2    Wu, Y.3    Fish, G.S.4    Galko, M.J.5
  • 28
    • 0037025213 scopus 로고    scopus 로고
    • Activation of Drosophila toll during fungal infection by a blood serine protease
    • DOI 10.1126/science.1072391
    • Ligoxygakis P, Pelte N, Hoffmann JA, Reichhart JM (2002a) Activation of Drosophila Toll during fungal infection by a blood serine protease. Science 297: 114-116 (Pubitemid 34743106)
    • (2002) Science , vol.297 , Issue.5578 , pp. 114-116
    • Ligoxygakis, P.1    Pelte, N.2    Hoffmann, J.A.3    Reichhart, J.-M.4
  • 30
    • 37849046535 scopus 로고    scopus 로고
    • Challenges for modeling and interpreting the complex biology of severe injury and inflammation
    • DOI 10.1189/jlb.0607377
    • Lowry SF, Calvano SE (2008) Challenges for modeling and interpreting the complex biology of severe injury and inflammation. J Leukoc Biol 83: 553-557 (Pubitemid 351966864)
    • (2008) Journal of Leukocyte Biology , vol.83 , Issue.3 , pp. 553-557
    • Lowry, S.F.1    Calvano, S.E.2
  • 31
    • 17244367891 scopus 로고    scopus 로고
    • An epidermal barrier wound repair pathway in Drosophila is mediated by grainy head
    • DOI 10.1126/science.1107573
    • Mace KA, Pearson JC, McGinnis W (2005) An epidermal barrier wound repair pathway in Drosophila is mediated by grainy head. Science 308: 381-385 (Pubitemid 40530069)
    • (2005) Science , vol.308 , Issue.5720 , pp. 381-385
    • Mace, K.A.1    Pearson, J.C.2    McGinnis, W.3
  • 32
    • 0032519787 scopus 로고    scopus 로고
    • Puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila
    • Martin-Blanco E, Gampel A, Ring J, Virdee K, Kirov N, Tolkovsky AM, Martinez-Arias A (1998) puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila. Genes Dev 12: 557-570
    • (1998) Genes Dev , vol.12 , pp. 557-570
    • Martin-Blanco, E.1    Gampel, A.2    Ring, J.3    Virdee, K.4    Kirov, N.5    Tolkovsky, A.M.6    Martinez-Arias, A.7
  • 33
    • 77649181715 scopus 로고    scopus 로고
    • Prioritization of competing damage and developmental signals by migrating macrophages in the Drosophila embryo
    • Moreira S, Stramer B, Evans I, Wood W, Martin P (2010) Prioritization of competing damage and developmental signals by migrating macrophages in the Drosophila embryo. Curr Biol 20: 464-470
    • (2010) Curr Biol , vol.20 , pp. 464-470
    • Moreira, S.1    Stramer, B.2    Evans, I.3    Wood, W.4    Martin, P.5
  • 34
    • 0037055265 scopus 로고    scopus 로고
    • Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors
    • Motohashi H, O'Connor T, Katsuoka F, Engel JD, Yamamoto M (2002) Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors. Gene 294: 1-12
    • (2002) Gene , vol.294 , pp. 1-12
    • Motohashi, H.1    O'Connor, T.2    Katsuoka, F.3    Engel, J.D.4    Yamamoto, M.5
  • 35
    • 0027620526 scopus 로고
    • Melanogenesis and the generation of cytotoxic molecules during insect cellular immune reactions
    • Nappi AJ, Vass E (1993) Melanogenesis and the generation of cytotoxic molecules during insect cellular immune reactions. Pigment Cell Res 6: 117-126
    • (1993) Pigment Cell Res , vol.6 , pp. 117-126
    • Nappi, A.J.1    Vass, E.2
  • 36
    • 67649255876 scopus 로고    scopus 로고
    • A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
    • Niethammer P, Grabher C, Look AT, Mitchison TJ (2009) A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature 459: 996-999
    • (2009) Nature , vol.459 , pp. 996-999
    • Niethammer, P.1    Grabher, C.2    Look, A.T.3    Mitchison, T.J.4
  • 37
    • 0035101409 scopus 로고    scopus 로고
    • Hydrogen peroxide acts as a second messenger for the induction of defense genes in tomato plants in response to wounding, systemin, and methyl jasmonate
    • DOI 10.1105/tpc.13.1.179
    • Orozco-Cardenas ML, Narvaez-Vasquez J, Ryan CA (2001) Hydrogen peroxide acts as a second messenger for the induction of defense genes in tomato plants in response to wounding, systemin, and methyl jasmonate. Plant Cell 13: 179-191 (Pubitemid 32177042)
    • (2001) Plant Cell , vol.13 , Issue.1 , pp. 179-191
    • Orozco-Cardenas, M.L.1    Narvaez-Vasquez, J.2    Ryan, C.A.3
  • 38
    • 70349446465 scopus 로고    scopus 로고
    • Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation
    • Owusu-Ansah E, Banerjee U (2009) Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation. Nature 461: 537-541
    • (2009) Nature , vol.461 , pp. 537-541
    • Owusu-Ansah, E.1    Banerjee, U.2
  • 39
    • 84863249589 scopus 로고
    • Etudes sur la maladie des vers a soie
    • Pasteur L (1870) Etudes sur la maladie des vers a soie. Oeuvres de Pasteur 4: 1926
    • (1870) Oeuvres de Pasteur , vol.4 , pp. 1926
    • Pasteur, L.1
  • 41
    • 0036149337 scopus 로고    scopus 로고
    • JNK signaling pathway is required for efficient wound healing in Drosophila
    • DOI 10.1006/dbio.2001.0502
    • Ramet M, Lanot R, Zachary D, Manfruelli P (2002) JNK signaling pathway is required for efficient wound healing in Drosophila. Dev Biol 241: 145-156 (Pubitemid 34066768)
    • (2002) Developmental Biology , vol.241 , Issue.1 , pp. 145-156
    • Ramet, M.1    Lanot, R.2    Zachary, D.3    Manfruelli, P.4
  • 42
    • 33745631769 scopus 로고    scopus 로고
    • Cell signaling. H2O2, a necessary evil for cell signaling
    • Rhee SG (2006) Cell signaling. H2O2, a necessary evil for cell signaling. Science 312: 1882-1883
    • (2006) Science , vol.312 , pp. 1882-1883
    • Rhee, S.G.1
  • 43
    • 0034633602 scopus 로고    scopus 로고
    • Hydrogen peroxide: A key messenger that modulates protein phosphorylation through cysteine oxidation
    • Rhee SG, Bae YS, Lee SR, Kwon J (2000) Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation. Sci STKE 2000: PE1
    • (2000) Sci STKE , vol.2000
    • Rhee, S.G.1    Bae, Y.S.2    Lee, S.R.3    Kwon, J.4
  • 44
    • 19444375216 scopus 로고    scopus 로고
    • Peroxiredoxins: A historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling
    • Rhee SG, Chae HZ, Kim K (2005) Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling. Free Radic Biol Med 38: 1543-1552
    • (2005) Free Radic Biol Med , vol.38 , pp. 1543-1552
    • Rhee, S.G.1    Chae, H.Z.2    Kim, K.3
  • 46
    • 0037472685 scopus 로고    scopus 로고
    • Serine proteases and their homologs in the Drosophila melanogaster genome: An initial analysis of sequence conservation and phylogenetic relationships
    • DOI 10.1016/S0378-1119(02)01187-3
    • Ross J, Jiang H, Kanost MR, Wang Y (2003) Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships. Gene 304: 117-131 (Pubitemid 36140137)
    • (2003) Gene , vol.304 , Issue.1-2 , pp. 117-131
    • Ross, J.1    Jiang, H.2    Kanost, M.R.3    Wang, Y.4
  • 47
    • 28844474578 scopus 로고    scopus 로고
    • Dermal wound healing is subject to redox control
    • DOI 10.1016/j.ymthe.2005.07.684, PII S1525001605014085
    • Roy S, Khanna S, Nallu K, Hunt TK, Sen CK (2006) Dermal wound healing is subject to redox control. Mol Ther 13: 211-220 (Pubitemid 41763500)
    • (2006) Molecular Therapy , vol.13 , Issue.1 , pp. 211-220
    • Roy, S.1    Khanna, S.2    Nallu, K.3    Hunt, T.K.4    Sen, C.K.5
  • 49
    • 54849425525 scopus 로고    scopus 로고
    • Drosophila Serpin-28D regulates hemolymph phenoloxidase activity and adult pigmentation
    • Scherfer C, Tang H, Kambris Z, Lhocine N, Hashimoto C, Lemaitre B (2008) Drosophila Serpin-28D regulates hemolymph phenoloxidase activity and adult pigmentation. Dev Biol 323: 189-196
    • (2008) Dev Biol , vol.323 , pp. 189-196
    • Scherfer, C.1    Tang, H.2    Kambris, Z.3    Lhocine, N.4    Hashimoto, C.5    Lemaitre, B.6
  • 50
    • 20444480631 scopus 로고    scopus 로고
    • Systemic signaling in the wound response
    • DOI 10.1016/j.pbi.2005.05.008, PII S1369526605000695, Biotic Interactions
    • Schilmiller AL, Howe GA (2005) Systemic signaling in the wound response. Curr Opin Plant Biol 8: 369-377 (Pubitemid 40817378)
    • (2005) Current Opinion in Plant Biology , vol.8 , Issue.4 , pp. 369-377
    • Schilmiller, A.L.1    Howe, G.A.2
  • 51
    • 84954358205 scopus 로고    scopus 로고
    • Two ways to survive infection: What resistance and tolerance can teach us about treating infectious diseases
    • Schneider DS, Ayres JS (2008) Two ways to survive infection: what resistance and tolerance can teach us about treating infectious diseases. Nat Rev Immunol 8: 889-895
    • (2008) Nat Rev Immunol , vol.8 , pp. 889-895
    • Schneider, D.S.1    Ayres, J.S.2
  • 52
    • 0033554605 scopus 로고    scopus 로고
    • EPR detection of reactive oxygen species in hemolymph of Galleria mellonella and Dendrolimus superans sibiricus (Lepidoptera) larvae
    • DOI 10.1006/bbrc.1999.1504
    • Slepneva IA, Glupov VV, Sergeeva SV, Khramtsov VV (1999) EPR detection of reactive oxygen species in hemolymph of Galleria mellonella and Dendrolimus superans sibiricus (Lepidoptera) larvae. Biochem Biophys Res Commun 264: 212-215 (Pubitemid 29500490)
    • (1999) Biochemical and Biophysical Research Communications , vol.264 , Issue.1 , pp. 212-215
    • Slepneva, I.A.1    Glupov, V.V.2    Sergeeva, S.V.3    Khramtsov, V.V.4
  • 53
    • 43049147119 scopus 로고    scopus 로고
    • Gene induction following wounding of wild-type versus macrophage-deficient Drosophila embryos
    • DOI 10.1038/embor.2008.34, PII EMBOR200834
    • Stramer B, Winfield M, Shaw T, Millard TH, Woolner S, Martin P (2008) Gene induction following wounding of wild-type versus macrophage-deficient Drosophila embryos. EMBO Rep 9: 465-471 (Pubitemid 351627285)
    • (2008) EMBO Reports , vol.9 , Issue.5 , pp. 465-471
    • Stramer, B.1    Winfield, M.2    Shaw, T.3    Millard, T.H.4    Woolner, S.5    Martin, P.6
  • 54
    • 77953012548 scopus 로고    scopus 로고
    • Stress-activated cap'n'collar transcription factors in aging and human disease
    • Sykiotis GP, Bohmann D (2010) Stress-activated cap'n'collar transcription factors in aging and human disease. Sci Signal 3: re3
    • (2010) Sci Signal , vol.3
    • Sykiotis, G.P.1    Bohmann, D.2
  • 55
    • 33748795547 scopus 로고    scopus 로고
    • Two proteases defining a melanization cascade in the immune system of Drosophila
    • DOI 10.1074/jbc.M601642200
    • Tang H, Kambris Z, Lemaitre B, Hashimoto C (2006) Two proteases defining a melanization cascade in the immune system of Drosophila. J Biol Chem 281: 28097-28104 (Pubitemid 44414523)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.38 , pp. 28097-28104
    • Tang, H.1    Kambris, Z.2    Lemaitre, B.3    Hashimoto, C.4
  • 56
    • 53249151998 scopus 로고    scopus 로고
    • A serpin that regulates immune melanization in the respiratory system of Drosophila
    • Tang H, Kambris Z, Lemaitre B, Hashimoto C (2008) A serpin that regulates immune melanization in the respiratory system of Drosophila. Dev Cell 15: 617-626
    • (2008) Dev Cell , vol.15 , pp. 617-626
    • Tang, H.1    Kambris, Z.2    Lemaitre, B.3    Hashimoto, C.4
  • 57
    • 0242362732 scopus 로고    scopus 로고
    • JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila
    • DOI 10.1016/S1534-5807(03)00323-X, PII S153458070300323X
    • Wang MC, Bohmann D, Jasper H (2003) JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila. Dev Cell 5: 811-816 (Pubitemid 37362223)
    • (2003) Developmental Cell , vol.5 , Issue.5 , pp. 811-816
    • Wang, M.C.1    Bohmann, D.2    Jasper, H.3
  • 58
    • 76749102420 scopus 로고    scopus 로고
    • Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling
    • Woo HA, Yim SH, Shin DH, Kang D, Yu DY, Rhee SG (2010) Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling. Cell 140: 517-528
    • (2010) Cell , vol.140 , pp. 517-528
    • Woo, H.A.1    Yim, S.H.2    Shin, D.H.3    Kang, D.4    Yu, D.Y.5    Rhee, S.G.6
  • 59
    • 34547539768 scopus 로고    scopus 로고
    • Broad-spectrum antimicrobial activity of the reactive compounds generated in vitro by Manduca sexta phenoloxidase
    • DOI 10.1016/j.ibmb.2007.05.001, PII S0965174807001026
    • Zhao P, Li J, Wang Y, Jiang H (2007) Broad-spectrum antimicrobial activity of the reactive compounds generated in vitro by Manduca sexta phenoloxidase. Insect Biochem Mol Biol 37: 952-959 (Pubitemid 47187724)
    • (2007) Insect Biochemistry and Molecular Biology , vol.37 , Issue.9 , pp. 952-959
    • Zhao, P.1    Li, J.2    Wang, Y.3    Jiang, H.4
  • 60


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.