Melatonin Modulates Endoplasmic Reticulum Stress and Akt/GSK3-Beta Signaling Pathway in a Rat Model of Renal Warm Ischemia Reperfusion

Analytical Cellular Pathology

Volumn 2015, Issue , 2015, Pages

  Hadj Ayed Tka, Kaouther ^a   Mahfoudh Boussaid, Asma ^a   Zaouali, Mohamed Amine ^a   Kammoun, Rym ^b   Bejaoui, Mohamed ^c   Ghoul Mazgar, Sonia ^b   Rosello Catafau, Joan ^c   Ben Abdennebi, Hassen ^a  

^a UNIVERSITY OF MONASTIR   (Tunisia)

^b UNIVERSITY OF MONASTIR   (Tunisia)

^c INST D INVESTIGACIONS B   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CREATININE; GLUCOSE REGULATED PROTEIN 78; GLYCOGEN SYNTHASE KINASE 3BETA; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; LACTATE DEHYDROGENASE; MALONALDEHYDE; MELATONIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; VOLTAGE DEPENDENT ANION CHANNEL; X BOX BINDING PROTEIN 1; GLYCOGEN SYNTHASE KINASE 3; GSK3B PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CREATININE CLEARANCE; CYTOLYSIS; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; ENZYME PHOSPHORYLATION; HISTOPATHOLOGY; INTRACELLULAR SIGNALING; KIDNEY FUNCTION; KIDNEY ISCHEMIA; LIPID PEROXIDATION; MALE; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; RENAL PROTECTION; WESTERN BLOTTING; ANIMAL; BLOOD; DRUG EFFECTS; ENZYMOLOGY; ISCHEMIA; KIDNEY; METABOLISM; PATHOLOGY; PHOSPHORYLATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; WISTAR RAT;

ANIMALS; BLOTTING, WESTERN; CREATININE; ENDOPLASMIC RETICULUM STRESS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; KIDNEY; L-LACTATE DEHYDROGENASE; MALE; MALONDIALDEHYDE; MELATONIN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS, WISTAR; REPERFUSION INJURY; SIGNAL TRANSDUCTION; WARM ISCHEMIA;

EID: 84953889209     PISSN: 22107177     EISSN: 22107185     Source Type: Journal    
DOI: 10.1155/2015/635172     Document Type: Article

References (52)

1. S. Rodríguez-Reynoso, C. Leal, E. Portilla-De Buen, J. C. Castillo, and F. Ramos-Solano, "Melatonin ameliorates renal ischemia/reperfusion injury, " Journal of Surgical Research, vol. 116, no. 2, pp. 242-247, 2004.
2. N. Arfian, N. Emoto, N. Vignon-Zellweger, K. Nakayama, K. Yagi, and K.-I. Hirata, "ET-1 deletion from endothelial cells protects the kidney during the extension phase of ischemia/ reperfusion injury, " Biochemical and Biophysical Research Communications, vol. 425, no. 2, pp. 443-449, 2012.
3. R. Inagi, "Endoplasmic reticulumstress in the kidney as a novel mediator of kidney injury, " Nephron-Experimental Nephrology, vol. 112, no. 1, pp. e1-e9, 2009.
4. S. Sharma, J. Sarkar, C. Haldar, and S. Sinha, "Melatoninreverses fas, E2F-1 and endoplasmic reticulumstressmediated apoptosis and dysregulation of autophagy induced by the herbicide atrazine inmurine splenocytes, " PLoS ONE, vol. 9, no. 9, Article ID e108602, 2014.
5. I. Ben Mosbah, I. Alfany-Fernández, C. Martel et al., "Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemiareperfusion, " Cell Death and Disease, vol. 1, no. 7, article e52, 2010.
6. J. Sehajpal, T. Kaur, R. Bhatti, and A. P. Singh, "Role of progesterone in melatonin-mediated protection against acute kidney injury, " Journal of Surgical Research, vol. 191, no. 2, pp. 441-447, 2014.
7. R. J. Reiter, D.-X. Tan, L. C. Manchester, and W. Qi, "Biochemical reactivity of melatonin with reactive oxygen and nitrogen species: a review of the evidence, " Cell Biochemistry and Biophysics, vol. 34, no. 2, pp. 237-256, 2001.
8. W. Z. Wang, X.-H. Fang, L. L. Stephenson, X. Zhang, K. T. Khiabani, and W. A. Zamboni, "Melatonin attenuates I/Rinduced mitochondrial dysfunction in skeletal muscle, " Journal of Surgical Research, vol. 171, no. 1, pp. 108-113, 2011.
9. A. Galano, D. X. Tan, and R. J. Reiter, "Melatonin as a natural ally against oxidative stress: a physicochemical examination, " Journal of Pineal Research, vol. 51, no. 1, pp. 1-16, 2011.
10. J. L. Mauriz, P. S. Collado, C. Veneroso, R. J. Reiter, and J. González-Gallego, "A review of the molecular aspects of melatonins anti-inflammatory actions: recent insights and new perspectives, " Journal of Pineal Research, vol. 54, no. 1, pp. 1-14, 2013.
11. W. Balduini, S. Carloni, S. Perrone et al., "The use of melatonin in hypoxic-ischemic brain damage: an experimental study, " Journal of Maternal-Fetal and Neonatal Medicine, vol. 25, no. 1, pp. 119-124, 2012.
12. A. Lochner, B. Huisamen, and F. Nduhirabandi, "Cardioprotective effect ofmelatonin against ischaemia/reperfusion damage, " Frontiers in Bioscience, vol. 5, no. 1, pp. 305-315, 2013.
13. A. Mahfoudh-Boussaid, M. A. Zaouali, T. Hauet et al., "Attenuation of endoplasmic reticulum stress and mitochondrial injury in kidney with ischemic postconditioning application and trimetazidine treatment, " Journal of Biomedical Science, vol. 19, pp. 71-84, 2012.
14. Z. Kurcer, E. Oguz, H. Ozbilge et al., "Melatonin protects from ischemia/reperfusion-induced renal injury in rats: this effect is not mediated by proinflammatory cytokines, " Journal of Pineal Research, vol. 43, no. 2, pp. 172-178, 2007.
15. I. B. Mosbah, J. Roselló-Catafau, R. Franco-Gou et al., "Preservation of steatotic livers in IGL-1 solution, " Liver Transplantation, vol. 12, no. 8, pp. 1215-1223, 2006.
16. P. Jablonski, B. O. Howden, D. A. Rae, C. S. Birrell, V. C. Marshall, and J. Tange, "An experimental model for assessment of renal recovery from warmischemia, " Transplantation, vol. 35, no. 3, pp. 198-204, 1983.
17. J. Chen, W. Wang, Q. Zhang et al., "Low molecular weight fucoidan against renal ischemia-reperfusion injury via inhibition of the MAPK signaling pathway, " PLoS ONE, vol. 8, no. 2, Article ID e56224, 2013.
18. L.-T. Wang, B.-L. Chen, C.-T. Wu, K.-H. Huang, C.-K. Chiang, and S. H. Liu, "Protective role of AMP-Activated protein kinase-evoked autophagy on an in vitro model of ischemia/reperfusion-induced renal tubular cell injury, " PLoS ONE, vol. 8, no. 11, Article ID e79814, 2013.
19. Z. Chen, C. C. Chua, J. Gao et al., "Prevention of ischemia/ reperfusion-induced cardiac apoptosis and injury bymelatonin is independent of glutathione peroxdiase 1, " Journal of Pineal Research, vol. 46, no. 2, pp. 235-241, 2009.
20. Y. Okatani, A. Wakatsuki, R. J. Reiter, H. Enzan, and Y. Miyahara, "Protective effect ofmelatoninagainstmitochondrial injury induced by ischemia and reperfusion of rat liver, " European Journal of Pharmacology, vol. 469, no. 1-3, pp. 145-152, 2003.
21. P.-O. Koh, "Melatonin attenuates the focal cerebral ischemic injury by inhibiting the dissociation of pBad from 14-3-3, " Journal of Pineal Research, vol. 44, no. 1, pp. 101-106, 2008.
22. O. R. Kunduzova, G. Escourrou, M.-H. Seguelas et al., "Prevention of apoptotic and necrotic cell death, caspase-3 activation, and renal dysfunction by melatonin after ischemia/ reperfusion, " The FASEB Journal, vol. 17, no. 8, pp. 872-874, 2003.
23. Z. Li, A. Nickkholgh, X. Yi et al., "Melatonin protects kidney grafts from ischemia/reperfusion injury through inhibition of NF-kB and apoptosis after experimental kidney transplantation, " Journal of Pineal Research, vol. 46, no. 4, pp. 365-372, 2009.
24. T. Aktoz, N. Aydogdu, B. Alagol, O. Yalcin, G. Huseyinova, and I. H. Atakan, "The protective effects of melatonin and vitamin E against renal ischemia-reperfusion injury in rats, " Renal Failure, vol. 29, no. 5, pp. 535-542, 2007.
25. A. D. Yalcin, A. Bisgin, R. H. Erbay et al., "Trimetazidine effect on burn-induced intestinal mucosal injury and kidney damage in rats, " International Journal of Burns and Trauma, vol. 2, pp. 110-117, 2012.
26. D. Y. Yoo, W. Kim, C. H. Lee et al., "Melatonin improves Dgalactose-induced aging effects on behavior, neurogenesis, and lipid peroxidation in the mouse dentate gyrus via increasing pCREB expression, " Journal of Pineal Research, vol. 52, no. 1, pp. 21-28, 2012.
27. N. Ersoz, A. Guven, T. Cayci et al., "Comparison of the efficacy of melatonin and 1400w on renal ischemia/reperfusion injury: a role for inhibiting iNOS, " Renal Failure, vol. 31, no. 8, pp. 704-710, 2009.
28. B. Bailly-Maitre, C. Fondevila, F. Kaldas et al., "Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury, " Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 8, pp. 2809-2814, 2006.
29. G. Kuznetsov, K. T. Bush, P. L. Zhang, and S. K. Nigam, "Perturbations inmaturation of secretory proteins and their association with endoplasmic reticulum chaperones in a cell culture model for epithelial ischemia, " Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 16, pp. 8584-8589, 1996.
30. M. J. Tuñõn, B. San-Miguel, I. Crespo et al., "Melatonin treatment reduces endoplasmic reticulumstress and modulates the unfolded protein response in rabbits with lethal fulminant hepatitis of viral origin, " Journal of Pineal Research, vol. 55, no. 3, pp. 221-228, 2013.
31. M. A. Zaouali, E. Boncompagni, R. J. Reiter et al., "AMPK involment in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: a role for melatonin and trimetazidine cocktail, " Journal of Pineal Research, vol. 55, pp. 65-78, 2013.
32. A.M. Y. Lin, S. F. Fang, P. L. Chao, and C. H. Yang, "Melatonin attenuates arsenite-induced apoptosis in rat brain: involvement of mitochondrial and endoplasmic reticulum pathways and aggregation of -synuclein, " Journal of Pineal Research, vol. 43, no. 2, pp. 163-171, 2007.
33. L. Yu, M. Lu, P. Wang, and X. Chen, "TrichostatinAameliorates myocardial ischemia/reperfusion injury through inhibition of endoplasmic reticulum stress-induced apoptosis, " Archives of Medical Research, vol. 43, no. 3, pp. 190-196, 2012.
34. M. Kitamura, "Endoplasmic reticulumstress and unfolded protein response in renal pathophysiology: janus faces, " American Journal of Physiology: Renal Physiology, vol. 295, no. 2, pp. F323-F334, 2008.
35. K. Zhang and R. J. Kaufman, "From endoplasmic-reticulum stress to the inflammatory response, " Nature, vol. 454, no. 7203, pp. 455-462, 2008.
36. C. Xu, B. Bailly-Maitre, and J. C. Reed, "Endoplasmic reticulum stress: cell life and death decisions, " Journal of Clinical Investigation, vol. 115, no. 10, pp. 2656-2664, 2005.
37. E. L. Marderstein, B. Bucher, Z. Guo, X. Feng, K. Reid, and D. A. Geller, "Protection of rat hepatocytes from apoptosis by inhibition of c-Jun N-Terminal kinase, " Surgery, vol. 134, no. 2, pp. 280-284, 2003.
38. T. Yin, G. Sandhu, C.D. Wolfgang et al., "Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney, " The Journal of Biological Chemistry, vol. 272, no. 32, pp. 19943-19950, 1997.
39. X. Yang, L. Qin, J. Liu, L. Tian, and H. Qian, "17-Estradiol protects the liver against cold ischemia/reperfusion injury through the Akt kinase pathway, " Journal of Surgical Research, vol. 178, no. 2, pp. 996-1002, 2012.
40. S.-J. Fang, X.-S. Wu, Z.-H. Han et al., "Neuregulin-1 preconditioning protects the heart against ischemia/reperfusion injury through a PI3K/Akt-dependent mechanism, " Chinese Medical Journal, vol. 123, no. 24, pp. 3597-3604, 2010.
41. A. Satake, M. Takaoka, M. Nishikawa et al., "Protective effect of 17 estradiol on ischemic acute renal failure through the PI3K/Akt/eNOS pathway, " Kidney International, vol. 73, no. 3, pp. 308-317, 2008.
42. M. A. Zaouali, S. Padrissa-Altes, I. B. Mosbah et al., "Improved rat steatotic and nonsteatotic liver preservation by the addition of epidermal growth factor and insulin-like growth factor-I to University ofWisconsin solution, " Liver Transplantation, vol. 16, no. 9, pp. 1098-1111, 2010.
43. J. Song, S.M. Kang, W.T. Lee, K.A. Park, K.M. Lee, and J.E .Lee, "The benefecial effect of melatonin in brain endothelial cells against oxygen-glucose deprivation followed by reperfusion induced injury, " OxidativeMedicine and Cellular Longevity, vol. 2014, Article ID639531, 14 pages, 2014.
44. P.O. Koh, "Melatonin prevents hepatic injury-induced decrease inAkt downstream targets phosphorylations, " Journal of Pineal Research, vol. 51, no. 2, pp. 214-219, 2011.
45. I. Kyriazis, G. C. Kagadis, P. Kallidonis et al., "PDE5 inhibition against acute renal ischemia reperfusion injury in rats: does vardenafil offer protection?" World Journal of Urology, vol. 31, no. 3, pp. 597-602, 2013.
46. T. Miura, M. Nishihara, and T. Miki, "Drug development targeting the glycogen synthase kinase-3beta (GSK-3beta) mediated signal transduction pathway: role of GSK-3beta in myocardial protection against ischemia reperfusion injury, " Journal of Pharmacological Sciences, vol. 109, no. 2, pp. 162-167, 2009.
47. P.-O. Koh, "Melatonin attenuates the cerebral ischemic injury via the MEK/ERK/p90RSK/Bad signaling cascade, " Journal of Veterinary Medical Science, vol. 70, no. 11, pp. 1219-1223, 2008.
48. X. Lv, J. Tan, D. Liu, P. Wu, and X. Cui, "Intratracheal administration of p38 short-hairpin RNA plasmid ameliorates lung ischemia-reperfusion injury in rats, " Journal of Heart and Lung Transplantation, vol. 31, no. 6, pp. 655-662, 2012.
49. Y. Wang, "Mitogen-Activated protein kinases in heart development and diseases, " Circulation, vol. 116, no. 12, pp. 1413-1423, 2007.
50. J. E. Clark, N. Sarafraz, and M. S. Marber, "Potential of p38-MAPK inhibitors in the treatment of ischaemic heart disease, " Pharmacology and Therapeutics, vol. 116, no. 2, pp. 192-206, 2007.
51. B. A. Rose, T. Force, and Y. Wang, "Mitogen-Activated protein kinase signaling in the heart: angels versus demons in a heartbreaking tale, " Physiological Reviews, vol. 90, no. 4, pp. 1507-1546, 2010.
52. G. Hernández, H. Lal, M. Fidalgo et al., "A novel cardioprotective p38-MAPK/mTOR pathway, " Experimental Cell Research, vol. 317, no. 20, pp. 2938-2949, 2011.