메뉴 건너뛰기




Volumn 52, Issue 1, 2012, Pages 21-28

Melatonin improves d -galactose-induced aging effects on behavior, neurogenesis, and lipid peroxidation in the mouse dentate gyrus via increasing pCREB expression

Author keywords

d galactose; doublecortin; Ki67; melatonin; memory deficit; neuronal damage; pCREB

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GALACTOSE; KI 67 ANTIGEN; MALONALDEHYDE; MELATONIN;

EID: 83555165136     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2011.00912.x     Document Type: Article
Times cited : (111)

References (68)
  • 1
    • 78349309044 scopus 로고    scopus 로고
    • Young hippocampal neurons are critical for recent and remote spatial memory in adult mice
    • Goodman T, Trouche S, Massou I, et al., Young hippocampal neurons are critical for recent and remote spatial memory in adult mice. Neuroscience 2010; 171: 769-778.
    • (2010) Neuroscience , vol.171 , pp. 769-778
    • Goodman, T.1    Trouche, S.2    Massou, I.3
  • 2
    • 79952591317 scopus 로고    scopus 로고
    • A new chapter in the field of memory: Adult hippocampal neurogenesis
    • Koehl M, Abrous DN,. A new chapter in the field of memory: adult hippocampal neurogenesis. Eur J Neurosci 2011; 33: 1101-1114.
    • (2011) Eur J Neurosci , vol.33 , pp. 1101-1114
    • Koehl, M.1    Abrous, D.N.2
  • 3
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Beckman KB, Ames BN,. The free radical theory of aging matures. Physiol Rev 1998; 78: 547-581. (Pubitemid 28182903)
    • (1998) Physiological Reviews , vol.78 , Issue.2 , pp. 547-581
    • Beckman, K.B.1    Ames, B.N.2
  • 5
    • 33646101468 scopus 로고    scopus 로고
    • Aging-dependent alterations in synaptic plasticity and memory in mice that overexpress extracellular superoxide dismutase
    • DOI 10.1523/JNEUROSCI.5566-05.2006
    • Hu D, Serrano F, Oury TD, et al., Aging-dependent alterations in synaptic plasticity and memory in mice that overexpress extracellular superoxide dismutase. J Neurosci 2006; 26: 3933-3941. (Pubitemid 44315413)
    • (2006) Journal of Neuroscience , vol.26 , Issue.15 , pp. 3933-3941
    • Hu, D.1    Serrano, F.2    Oury, T.D.3    Klann, E.4
  • 6
    • 1242316182 scopus 로고    scopus 로고
    • Prominent decline of newborn cell proliferation, differentiation, and apoptosis in the aging dentate gyrus, in absence of an age-related hypothalamus-pituitary-adrenal axis activation
    • DOI 10.1016/S0197-4580(03)00090-3
    • Heine VM, Maslam S, Joëls M, et al., Prominent decline of newborn cell proliferation, differentiation, and apoptosis in the aging dentate gyrus, in absence of an age-related hypothalamus-pituitary-adrenal axis activation. Neurobiol Aging 2004; 25: 361-375. (Pubitemid 38220972)
    • (2004) Neurobiology of Aging , vol.25 , Issue.3 , pp. 361-375
    • Heine, V.M.1    Maslam, S.2    Joels, M.3    Lucassen, P.J.4
  • 7
    • 34447648402 scopus 로고    scopus 로고
    • Differences in doublecortin immunoreactivity and protein levels in the hippocampal dentate gyrus between adult and aged dogs
    • DOI 10.1007/s11064-007-9366-1
    • Hwang IK, Yoo KY, Li H, et al., Differences in doublecortin immunoreactivity and protein levels in the hippocampal dentate gyrus between adult and aged dogs. Neurochem Res 2007; 32: 1604-1609. (Pubitemid 47094424)
    • (2007) Neurochemical Research , vol.32 , Issue.9 , pp. 1604-1609
    • Hwang, I.K.1    Yoo, K.-Y.2    Li, H.3    Choi, J.H.4    Kwon, Y.-G.5    Ahn, Y.6    Lee, I.S.7    Won, M.H.8
  • 8
    • 41049110042 scopus 로고    scopus 로고
    • Age-related differentiation in newly generated DCX immunoreactive neurons in the subgranular zone of the gerbil dentate gyrus
    • Hwang IK, Yoo KY, Yi SS, et al., Age-related differentiation in newly generated DCX immunoreactive neurons in the subgranular zone of the gerbil dentate gyrus. Neurochem Res 2008; 33: 867-872.
    • (2008) Neurochem Res , vol.33 , pp. 867-872
    • Hwang, I.K.1    Yoo, K.Y.2    Yi, S.S.3
  • 9
    • 0029863342 scopus 로고    scopus 로고
    • Neurogenesis in the dentate gyrus of the adult rat: Age-related decrease of neuronal progenitor proliferation
    • Kuhn HG, Dickinson-Anson H, Gage F,. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci 1996; 16: 2027-2033. (Pubitemid 26144015)
    • (1996) Journal of Neuroscience , vol.16 , Issue.6 , pp. 2027-2033
    • Kuhn, H.G.1    Dickinson-Anson, H.2    Gage, F.H.3
  • 10
    • 33751229947 scopus 로고    scopus 로고
    • The window and mechanisms of major age-related decline in the production of new neurons within the dentate gyrus of the hippocampus
    • DOI 10.1111/j.1474-9726.2006.00243.x
    • Rao MS, Hattiangady B, Shetty AK,. The window and mechanisms of major age-related decline in the production of new neurons within the dentate gyrus of the hippocampus. Aging Cell 2006; 5: 545-558. (Pubitemid 44782623)
    • (2006) Aging Cell , vol.5 , Issue.6 , pp. 545-558
    • Rao, M.S.1    Hattiangady, B.2    Shetty, A.K.3
  • 11
    • 0029586276 scopus 로고
    • Age-related production of new granule cells in the adult dentate gyrus
    • Seki T, Arai Y,. Age-related production of new granule cells in the adult dentate gyrus. Neuroreport 1995; 6: 2479-2482. (Pubitemid 26031190)
    • (1995) NeuroReport , vol.6 , Issue.18 , pp. 2479-2482
    • Seki, T.1    Arai, Y.2
  • 12
    • 0032969493 scopus 로고    scopus 로고
    • Advanced glycation in D-galactose induced mouse aging model
    • DOI 10.1016/S0047-6374(99)00022-6, PII S0047637499000226
    • Song X, Bao M, Li D, et al., Advanced glycation in D-galactose induced mouse aging model. Mech Ageing Dev 1999; 108: 239-251. (Pubitemid 29240629)
    • (1999) Mechanisms of Ageing and Development , vol.108 , Issue.3 , pp. 239-251
    • Song, X.1    Bao, M.2    Li, D.3    Li, Y.M.4
  • 13
    • 74049145365 scopus 로고    scopus 로고
    • Yam (Dioscorea pseudojaponica Yamamoto) ameliorates cognition deficit and attenuates oxidative damage in senescent mice induced by D-galactose
    • Chiu CS, Deng JS, Hsieh MT, et al., Yam (Dioscorea pseudojaponica Yamamoto) ameliorates cognition deficit and attenuates oxidative damage in senescent mice induced by D-galactose. Am J Chin Med 2009; 37: 889-902.
    • (2009) Am J Chin Med , vol.37 , pp. 889-902
    • Chiu, C.S.1    Deng, J.S.2    Hsieh, M.T.3
  • 16
    • 58149305975 scopus 로고    scopus 로고
    • Paeonol attenuates neurotoxicity and ameliorates cognitive impairment induced by d-galactose in ICR mice
    • Zhong SZ, Ge QH, Qu R, et al., Paeonol attenuates neurotoxicity and ameliorates cognitive impairment induced by d-galactose in ICR mice. J Neurol Sci 2009; 277: 58-64.
    • (2009) J Neurol Sci , vol.277 , pp. 58-64
    • Zhong, S.Z.1    Ge, Q.H.2    Qu, R.3
  • 17
    • 33746929523 scopus 로고    scopus 로고
    • Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: Protective effects of R-α-lipoic acid
    • DOI 10.1002/jnr.20899
    • Cui X, Zuo P, Zhang Q, et al., Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-α-lipoic acid. J Neurosci Res 2006; 84: 647-654. (Pubitemid 44196705)
    • (2006) Journal of Neuroscience Research , vol.84 , Issue.3 , pp. 647-654
    • Cui, X.1    Zuo, P.2    Zhang, Q.3    Li, X.4    Hu, Y.5    Long, J.6    Packer, L.7    Liu, J.8
  • 19
    • 0002979059 scopus 로고
    • Melatonin: A potent endogenous hydroxyl radical scavenger
    • Tan DX, Chen LD, Poeggeler B, et al., Melatonin: a potent endogenous hydroxyl radical scavenger. Endocr J 1993; 1: 57-60.
    • (1993) Endocr J , vol.1 , pp. 57-60
    • Tan, D.X.1    Chen, L.D.2    Poeggeler, B.3
  • 20
    • 71549120441 scopus 로고    scopus 로고
    • 2+-mediated permeability transition and beyond in rat brain astrocytes
    • 2+- mediated permeability transition and beyond in rat brain astrocytes. J Pineal Res 2010; 48: 20-38.
    • (2010) J Pineal Res , vol.48 , pp. 20-38
    • Jou, M.J.1    Peng, T.I.2    Hsu, L.F.3
  • 21
    • 75149124310 scopus 로고    scopus 로고
    • The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-α toxicity involves membrane melatonin receptors
    • Das A, McDowell M, Pava MJ, et al., The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-α toxicity involves membrane melatonin receptors. J Pineal Res 2010; 48: 157-169.
    • (2010) J Pineal Res , vol.48 , pp. 157-169
    • Das, A.1    McDowell, M.2    Pava, M.J.3
  • 22
    • 77950663581 scopus 로고    scopus 로고
    • Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease
    • Paradies G, Petrosillo G, Paradies V, et al., Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease. J Pineal Res 2010; 48: 297-310.
    • (2010) J Pineal Res , vol.48 , pp. 297-310
    • Paradies, G.1    Petrosillo, G.2    Paradies, V.3
  • 24
    • 34147213579 scopus 로고    scopus 로고
    • Melatonin influences the proliferative and differentiative activity of neural stem cells
    • DOI 10.1111/j.1600-079X.2007.00435.x
    • Moriya T, Horie N, Mitome M, et al., Melatonin influences the proliferative and differentiative activity of neural stem cells. J Pineal Res 2007; 42: 411-418. (Pubitemid 46581666)
    • (2007) Journal of Pineal Research , vol.42 , Issue.4 , pp. 411-418
    • Moriya, T.1    Horie, N.2    Mitome, M.3    Shinohara, K.4
  • 25
    • 67651100669 scopus 로고    scopus 로고
    • Melatonin modulates cell survival of new neurons in the hippocampus of adult mice
    • Ramírez-Rodríguez G, Klempin F, Babu H, et al., Melatonin modulates cell survival of new neurons in the hippocampus of adult mice. Neuropsychopharmacology 2009; 34: 2180-2191.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 2180-2191
    • Ramírez-Rodríguez, G.1    Klempin, F.2    Babu, H.3
  • 26
    • 78650117283 scopus 로고    scopus 로고
    • Chronic treatment with melatonin stimulates dendrite maturation and complexity in adult hippocampal neurogenesis of mice
    • Ramírez-Rodríguez G, Ortíz-López L, Domínguez-Alonso A, et al., Chronic treatment with melatonin stimulates dendrite maturation and complexity in adult hippocampal neurogenesis of mice. J Pineal Res 2011; 50: 29-37.
    • (2011) J Pineal Res , vol.50 , pp. 29-37
    • Ramírez-Rodríguez, G.1    Ortíz-López, L.2    Domínguez-Alonso, A.3
  • 27
    • 77956299657 scopus 로고    scopus 로고
    • Melatonin increases proliferation of cultured neural stem cells obtained from adult mouse subventricular zone
    • Sotthibundhu A, Phansuwan-Pujito P, Govitrapong P,. Melatonin increases proliferation of cultured neural stem cells obtained from adult mouse subventricular zone. J Pineal Res 2010; 49: 291-300.
    • (2010) J Pineal Res , vol.49 , pp. 291-300
    • Sotthibundhu, A.1    Phansuwan-Pujito, P.2    Govitrapong, P.3
  • 28
    • 57149139038 scopus 로고    scopus 로고
    • Cranial irradiation-induced inhibition of neurogenesis in hippocampal dentate gyrus of adult mice: Attenuation by melatonin pretreatment
    • Manda K, Ueno M, Anzai K,. Cranial irradiation-induced inhibition of neurogenesis in hippocampal dentate gyrus of adult mice: attenuation by melatonin pretreatment. J Pineal Res 2009; 46: 71-78.
    • (2009) J Pineal Res , vol.46 , pp. 71-78
    • Manda, K.1    Ueno, M.2    Anzai, K.3
  • 29
    • 53749104127 scopus 로고    scopus 로고
    • Space radiation-induced inhibition of neurogenesis in the hippocampal dentate gyrus and memory impairment in mice: Ameliorative potential of the melatonin metabolite, AFMK
    • Manda K, Ueno M, Anzai K,. Space radiation-induced inhibition of neurogenesis in the hippocampal dentate gyrus and memory impairment in mice: ameliorative potential of the melatonin metabolite, AFMK. J Pineal Res 2008; 45: 430-438.
    • (2008) J Pineal Res , vol.45 , pp. 430-438
    • Manda, K.1    Ueno, M.2    Anzai, K.3
  • 30
    • 70350048916 scopus 로고    scopus 로고
    • Melatonin promotes neurogenesis in dentate gyrus in the pinealectomized rat
    • Rennie K, De Butte M, Pappas BA,. Melatonin promotes neurogenesis in dentate gyrus in the pinealectomized rat. J Pineal Res 2009; 47: 313-317.
    • (2009) J Pineal Res , vol.47 , pp. 313-317
    • Rennie, K.1    De Butte, M.2    Pappas, B.A.3
  • 31
    • 55749101336 scopus 로고    scopus 로고
    • Melatonin attenuates the decrement of dendritic protein MAP-2 immuno-staining in the hippocampal CA1 and CA3 fields of the aging male rat
    • Prieto-Gómez B, Velázquez-Paniagua M, Cisneros LO, et al., Melatonin attenuates the decrement of dendritic protein MAP-2 immuno-staining in the hippocampal CA1 and CA3 fields of the aging male rat. Neurosci Lett 2008; 448: 56-61.
    • (2008) Neurosci Lett , vol.448 , pp. 56-61
    • Prieto-Gómez, B.1    Velázquez-Paniagua, M.2    Cisneros, L.O.3
  • 32
    • 78149426142 scopus 로고    scopus 로고
    • The roles of BDNF, pCREB and Wnt3a in the latent period preceding activation of progenitor cell mitosis in the adult dentate gyrus by fluoxetine
    • Pinnock SB, Blake AM, Platt NJ, et al., The roles of BDNF, pCREB and Wnt3a in the latent period preceding activation of progenitor cell mitosis in the adult dentate gyrus by fluoxetine. PLoS ONE 2010; 5: e13652.
    • (2010) PLoS ONE , vol.5
    • Pinnock, S.B.1    Blake, A.M.2    Platt, N.J.3
  • 36
    • 79959603490 scopus 로고    scopus 로고
    • Time course of postnatal distribution of doublecortin immunoreactive developing/maturing neurons in the somatosensory cortex and hippocampal CA1 region of C57BL/6 mice
    • Yoo DY, Yoo KY, Choi JW, et al., Time course of postnatal distribution of doublecortin immunoreactive developing/maturing neurons in the somatosensory cortex and hippocampal CA1 region of C57BL/6 mice. Cell Mol Neurobiol 2011; 31: 729-736.
    • (2011) Cell Mol Neurobiol , vol.31 , pp. 729-736
    • Yoo, D.Y.1    Yoo, K.Y.2    Choi, J.W.3
  • 37
    • 0019209714 scopus 로고
    • Pineal melatonin rhythm: reduction in aging Syrian hamsters
    • Reiter RJ, Richardson BA, Johnson LY, et al., Pineal melatonin rhythm: reduction in aging Syrian hamsters. Science 1980; 210: 1372-1373. (Pubitemid 11175499)
    • (1980) Science , vol.210 , Issue.4476 , pp. 1372-1373
    • Reiter, R.J.1    Richardson, B.A.2    Johnson, L.Y.3
  • 38
    • 0019405864 scopus 로고
    • Age-associated reduction in nocturnal pineal melatonin levels in female rats
    • Reiter RJ, Craft CM, Johnson JE Jr, et al., Age-associated reduction in nocturnal pineal melatonin levels in female rats. Endocrinology 1981; 109: 1295-1297. (Pubitemid 11008322)
    • (1981) Endocrinology , vol.109 , Issue.4 , pp. 1295-1297
    • Reiter, R.J.1    Craft, C.M.2    Johnson Jr., J.E.3
  • 39
    • 11444259804 scopus 로고    scopus 로고
    • Behavioural study of the D-galactose induced aging model in C57BL/6J mice
    • DOI 10.1016/j.bbr.2004.07.003, PII S016643280400261X
    • Wei H, Li L, Song Q, et al., Behavioural study of the D-galactose induced aging model in C57BL/6J mice. Behav Brain Res 2005; 157: 245-251. (Pubitemid 40082567)
    • (2005) Behavioural Brain Research , vol.157 , Issue.2 , pp. 245-251
    • Wei, H.1    Li, L.2    Song, Q.3    Ai, H.4    Chu, J.5    Li, W.6
  • 40
    • 46149105206 scopus 로고    scopus 로고
    • Temporal gene expression profile in hippocampus of mice treated with D-galactose
    • DOI 10.1007/s10571-007-9177-6
    • Wei H, Cai Y, Chu J, et al., Temporal gene expression profile in hippocampus of mice treated with D-galactose. Cell Mol Neurobiol 2008; 28: 781-794. (Pubitemid 351905067)
    • (2008) Cellular and Molecular Neurobiology , vol.28 , Issue.5 , pp. 781-794
    • Wei, H.1    Cai, Y.2    Chu, J.3    Li, C.4    Li, L.5
  • 41
    • 22044438835 scopus 로고    scopus 로고
    • Learning and memory deficits in rats induced by chronic thinner exposure are reversed by melatonin
    • DOI 10.1111/j.1600-079X.2005.00212.x
    • Baydas G, Ozveren F, Akdemir I, et al., Learning and memory deficits in rats induced by chronic thinner exposure are reversed by melatonin. J Pineal Res 2005; 39: 50-56. (Pubitemid 40966462)
    • (2005) Journal of Pineal Research , vol.39 , Issue.1 , pp. 50-56
    • Baydas, G.1    Ozveren, F.2    Akdemir, I.3    Tuzcu, M.4    Yasar, A.5
  • 42
    • 42149168418 scopus 로고    scopus 로고
    • Differential effects of melatonin on hippocampal neurodegeneration in different aged accelerated senescence prone mouse-8
    • Cheng S, Ma C, Qu H, et al., Differential effects of melatonin on hippocampal neurodegeneration in different aged accelerated senescence prone mouse-8. Neuro Endocrinol Lett 2008; 29: 91-99.
    • (2008) Neuro Endocrinol Lett , vol.29 , pp. 91-99
    • Cheng, S.1    Ma, C.2    Qu, H.3
  • 43
    • 34447130376 scopus 로고    scopus 로고
    • Melatonin and the human hippocampus, a time dependant interplay
    • DOI 10.1111/j.1600-079X.2007.00446.x
    • Gorfine T, Zisapel N,. Melatonin and the human hippocampus, a time dependent interplay. J Pineal Res 2007; 43: 80-86. (Pubitemid 47035225)
    • (2007) Journal of Pineal Research , vol.43 , Issue.1 , pp. 80-86
    • Gorfine, T.1    Zisapel, N.2
  • 44
    • 0035868536 scopus 로고    scopus 로고
    • Possible antioxidant mechanism in melatonin reversal of aging and chronic ethanol-induced amnesia in plus-maze and passive avoidance memory tasks
    • DOI 10.1016/S0891-5849(00)00447-0, PII S0891584900004470
    • Raghavendra V, Kulkarni SK,. Possible antioxidant mechanism in melatonin reversal of aging and chronic ethanol-induced amnesia in plus-maze and passive avoidance memory tasks. Free Radic Biol Med 2001; 30: 595-602. (Pubitemid 32280785)
    • (2001) Free Radical Biology and Medicine , vol.30 , Issue.6 , pp. 595-602
    • Raghavendra, V.1    Kulkarni, S.K.2
  • 45
    • 0036221784 scopus 로고    scopus 로고
    • The protective effects of melatonin from oxidative damage induced by amyloid beta-peptide 25-35 in middle-aged rats
    • DOI 10.1034/j.1600-079x.2002.1819.x
    • Shen YX, Xu SY, Wei W, et al., The protective effects of melatonin from oxidative damage induced by amyloid beta-peptide 25-35 in middle-aged rats. J Pineal Res 2002; 32: 85-89. (Pubitemid 34289585)
    • (2002) Journal of Pineal Research , vol.32 , Issue.2 , pp. 85-89
    • Shen, Y.X.1    Xu, S.Y.2    Wei, W.3    Sun, X.X.4    Liu, L.H.5    Yang, J.6    Dong, C.7
  • 46
    • 0038434113 scopus 로고    scopus 로고
    • Melatonin prevents cytoskeletal alterations and oxidative stress induced by okadaic acid in N1E-115 cells
    • DOI 10.1016/S0014-4886(03)00085-2
    • Benítez-King G, Túnez I, Bellon A, et al., Melatonin prevents cytoskeletal alterations and oxidative stress induced by okadaic acid in N1E-115 cells. Exp Neurol 2003; 182: 151-159. (Pubitemid 36776258)
    • (2003) Experimental Neurology , vol.182 , Issue.1 , pp. 151-159
    • Benitez-King, G.1    Tunez, I.2    Bellon, A.3    Ortiz, G.G.4    Anton-Tay, F.5
  • 47
    • 33644920991 scopus 로고    scopus 로고
    • Melatonin as a cytoskeletal modulator: Implications for cell physiology and disease
    • Benítez-King G,. Melatonin as a cytoskeletal modulator: implications for cell physiology and disease. J Pineal Res 2006; 40: 1-9.
    • (2006) J Pineal Res , vol.40 , pp. 1-9
    • Benítez-King, G.1
  • 48
    • 0029999707 scopus 로고    scopus 로고
    • Effect of melatonin on β-tubulin and MAP2 expression in NIE-115 cells
    • DOI 10.1007/BF02527721
    • Meléndez J, Maldonado V, Ortega A,. Effect of melatonin on β-tubulin and MAP2 expression in NIE-115 cells. Neurochem Res 1996; 21: 653-658. (Pubitemid 26251575)
    • (1996) Neurochemical Research , vol.21 , Issue.6 , pp. 653-658
    • Melendez, J.1    Maldonado, V.2    Ortega, A.3
  • 49
    • 67649905028 scopus 로고    scopus 로고
    • Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease
    • Olcese JM, Cao C, Mori T, et al., Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease. J Pineal Res 2009; 47: 82-96.
    • (2009) J Pineal Res , vol.47 , pp. 82-96
    • Olcese, J.M.1    Cao, C.2    Mori, T.3
  • 50
    • 0036227595 scopus 로고    scopus 로고
    • Melatonin reduces memory changes and neural oxidative damage in mice treated with D-galactose
    • DOI 10.1034/j.1600-079x.2002.1o850.x
    • Shen YX, Xu SY, Wei W, et al., Melatonin reduces memory changes and neural oxidative damage in mice treated with D-galactose. J Pineal Res 2002; 32: 173-178. (Pubitemid 34309884)
    • (2002) Journal of Pineal Research , vol.32 , Issue.3 , pp. 173-178
    • Shen, Y.-X.1    Xu, S.-Y.2    Wei, W.3    Sun, X.-X.4    Yang, J.5    Liu, L.-H.6    Dong, C.7
  • 51
    • 33847653731 scopus 로고    scopus 로고
    • Suppressive Effects of Melatonin on Amyloid-β-induced Glial Activation in Rat Hippocampus
    • DOI 10.1016/j.arcmed.2006.10.007, PII S0188440906003766
    • Shen Y, Zhang G, Liu L, et al., Suppressive effects of melatonin on amyloid-β-induced glial activation in rat hippocampus. Arch Med Res 2007; 38: 284-290. (Pubitemid 46366081)
    • (2007) Archives of Medical Research , vol.38 , Issue.3 , pp. 284-290
    • Shen, Y.1    Zhang, G.2    Liu, L.3    Xu, S.4
  • 52
    • 33845457292 scopus 로고    scopus 로고
    • Pinealectomy causes hippocampal CA1 and CA3 cell loss: Reversal by melatonin supplementation
    • DOI 10.1016/j.neurobiolaging.2005.12.004, PII S0197458005004288
    • De Butte M, Pappas BA,. Pinealectomy causes hippocampal CA1 and CA3 cell loss: reversal by melatonin supplementation. Neurobiol Aging 2007; 28: 306-313. (Pubitemid 44894630)
    • (2007) Neurobiology of Aging , vol.28 , Issue.2 , pp. 306-313
    • De Butte, M.1    Pappas, B.A.2
  • 53
    • 0035868717 scopus 로고    scopus 로고
    • Neurogenesis in the adult is involved in the formation of trace memories
    • DOI 10.1038/35066584
    • Shors TJ, Miesegaes G, Beylin A, et al., Neurogenesis in the adult is involved in the formation of trace memories. Nature 2001; 410: 372-376. (Pubitemid 32246054)
    • (2001) Nature , vol.410 , Issue.6826 , pp. 372-376
    • Shors, T.J.1    Miesegaes, G.2    Beylin, A.3    Zhao, M.4    Rydel, T.5    Gould, E.6
  • 54
    • 72049087712 scopus 로고    scopus 로고
    • Melatonin maintains adult hippocampal neurogenesis and cognitive functions after irradiation
    • Manda K, Reiter RJ,. Melatonin maintains adult hippocampal neurogenesis and cognitive functions after irradiation. Prog Neurobiol 2010; 90: 60-68.
    • (2010) Prog Neurobiol , vol.90 , pp. 60-68
    • Manda, K.1    Reiter, R.J.2
  • 55
    • 68249129060 scopus 로고    scopus 로고
    • Kynuramines, metabolites of melatonin and other indoles: The resurrection of an almost forgotten class of biogenic amines
    • Hardeland R, Tan DX, Reiter RJ,. Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines. J Pineal Res 2009; 47: 109-126.
    • (2009) J Pineal Res , vol.47 , pp. 109-126
    • Hardeland, R.1    Tan, D.X.2    Reiter, R.J.3
  • 56
    • 77955140547 scopus 로고    scopus 로고
    • 1-acetyl-5-methoxy-kynuramine formation from melatonin in mice
    • 1-acetyl-5-methoxy- kynuramine formation from melatonin in mice. J Pineal Res 2010; 49: 106-114.
    • (2010) J Pineal Res , vol.49 , pp. 106-114
    • Niu, S.1    Li, F.2    Tan, D.X.3
  • 57
    • 0031279007 scopus 로고    scopus 로고
    • Control of CREB phosphorylation and its role for induction of melatonin synthesis in rat pinealocytes
    • DOI 10.1016/S0248-4900(98)80006-3
    • Maronde E, Schomerus C, Stehle JH, et al., Control of CREB phosphorylation and its role for induction of melatonin synthesis in rat pinealocytes. Biol Cell 1997; 89: 505-511. (Pubitemid 28209698)
    • (1997) Biology of the Cell , vol.89 , Issue.8 , pp. 505-511
    • Maronde, E.1    Schomerus, C.2    Stehle, J.H.3    Korf, H.-W.4
  • 59
    • 0032848855 scopus 로고    scopus 로고
    • CREB phosphorylation and melatonin biosynthesis in the rat pineal gland: Involvement of cyclic AMP dependent protein kinase type II
    • DOI 10.1111/j.1600-079X.1999.tb00613.x
    • Maronde E, Wicht H, Taskén K, et al., CREB phosphorylation and melatonin biosynthesis in the rat pineal gland: involvement of cyclic AMP dependent protein kinase type II. J Pineal Res 1999; 27: 170-182. (Pubitemid 29487962)
    • (1999) Journal of Pineal Research , vol.27 , Issue.3 , pp. 170-182
    • Maronde, E.1    Wicht, H.2    Tasken, K.3    Genieser, H.-G.4    Dehghani, F.5    Olcese, J.6    Korf, H.-W.7
  • 60
    • 0037380957 scopus 로고    scopus 로고
    • Dephosphorylation of pCREB by protein serine/threonine phosphatases is involved in inactivation of Aanat gene transcription in rat pineal gland
    • Koch M, Mauhin V, Stehle JH, et al., Dephosphorylation of pCREB by protein serine/threonine phosphatases is involved in inactivation of Aanat gene transcription in rat pineal gland. J Neurochem 2003; 85: 170-179. (Pubitemid 36389707)
    • (2003) Journal of Neurochemistry , vol.85 , Issue.1 , pp. 170-179
    • Koch, M.1    Mauhin, V.2    Stehle, J.H.3    Schomerus, C.4    Korf, H.-W.5
  • 61
    • 0037369801 scopus 로고    scopus 로고
    • Norepinephrine-dependent phosphorylation of the transcription factor cyclic adenosine monophosphate responsive element-binding protein in bovine pinealocytes
    • DOI 10.1034/j.1600-079X.2003.00011.x
    • Schomerus C, Laedtke E, Korf HW,. Norepinephrine-dependent phosphorylation of the transcription factor cyclic adenosine monophosphate responsive element-binding protein in bovine pinealocytes. J Pineal Res 2003; 34: 103-109. (Pubitemid 36255918)
    • (2003) Journal of Pineal Research , vol.34 , Issue.2 , pp. 103-109
    • Schomerus, C.1    Laedtke, E.2    Korf, H.-W.3
  • 65
    • 33750078110 scopus 로고    scopus 로고
    • Altered growth and radiosensitivity in neural precursor cells subjected to oxidative stress
    • DOI 10.1080/09553000600887816, PII X86HK361625H0115
    • Limoli CL, Giedzinski E, Baure J, et al., Altered growth and radiosensitivity in neural precursor cells subjected to oxidative stress. Int J Radiat Biol 2006; 82: 640-647. (Pubitemid 44581947)
    • (2006) International Journal of Radiation Biology , vol.82 , Issue.9 , pp. 640-647
    • Limoli, C.L.1    Giedzinski, E.2    Baure, J.3    Rola, R.4    Fike, J.R.5
  • 66
    • 28244472094 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration induced by lipoteichoic acid from Staphylococcus aureus is mediated by glia activation, nitrosative and oxidative stress, and caspase activation
    • DOI 10.1111/j.1471-4159.2005.03422.x
    • Kinsner A, Pilotto V, Deininger S, et al., Inflammatory neurodegeneration induced by lipoteichoic acid from Staphylococcus aureus is mediated by glia activation, nitrosative and oxidative stress, and caspase activation. J Neurochem 2005; 95: 1132-1143. (Pubitemid 41713496)
    • (2005) Journal of Neurochemistry , vol.95 , Issue.4 , pp. 1132-1143
    • Kinsner, A.1    Pilotto, V.2    Deininger, S.3    Brown, G.C.4    Coecke, S.5    Hartung, T.6    Bal-Price, A.7
  • 67
    • 55349094995 scopus 로고    scopus 로고
    • Exogenous melatonin decreases age-induced lipid peroxidation in the brain
    • Akbulut KG, Gonül B, Akbulut H,. Exogenous melatonin decreases age-induced lipid peroxidation in the brain. Brain Res 2008; 1238: 31-35.
    • (2008) Brain Res , vol.1238 , pp. 31-35
    • Akbulut, K.G.1    Gonül, B.2    Akbulut, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.