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Volumn 16, Issue 1, 2016, Pages 1-11

Insights into Group 2 Innate Lymphoid Cells in Human Airway Disease

Author keywords

Airway; Allergy; Asthma; Group 2 innate lymphoid cells; ILC2

Indexed keywords

INTERLEUKIN 25; INTERLEUKIN 33; LIPOXIN A; PAPAIN; PROSTACYCLIN; THYMIC STROMAL LYMPHOPOIETIN; VASCULAR ENDOTHELIAL GROWTH INHIBITOR; ALLERGEN; CYTOKINE;

EID: 84953716658     PISSN: 15297322     EISSN: 15346315     Source Type: Journal    
DOI: 10.1007/s11882-015-0581-6     Document Type: Review
Times cited : (69)

References (124)
  • 1
    • 40049092917 scopus 로고    scopus 로고
    • Treatment strategies for allergy and asthma
    • PID: 18274559, COI: 1:CAS:528:DC%2BD1cXisVKjsrY%3D
    • Holgate ST, Polosa R. Treatment strategies for allergy and asthma. Nat Rev Immunol. 2008;8:218–30.
    • (2008) Nat Rev Immunol , vol.8 , pp. 218-230
    • Holgate, S.T.1    Polosa, R.2
  • 2
    • 55849148482 scopus 로고    scopus 로고
    • The cytokine network in asthma and chronic obstructive pulmonary disease
    • PID: 18982161, COI: 1:CAS:528:DC%2BD1cXhtlGltLrK
    • Barnes PJ. The cytokine network in asthma and chronic obstructive pulmonary disease. J Clin Invest. 2008;118:3546–56.
    • (2008) J Clin Invest , vol.118 , pp. 3546-3556
    • Barnes, P.J.1
  • 3
    • 18244405108 scopus 로고    scopus 로고
    • IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo
    • PID: 11754819, COI: 1:CAS:528:DC%2BD38Xhsl2ksA%3D%3D
    • Fort MM, Cheung J, Yen D, Li J, Zurawski SM, Lo S, et al. IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo. Immunity. 2001;15:985–95.
    • (2001) Immunity , vol.15 , pp. 985-995
    • Fort, M.M.1    Cheung, J.2    Yen, D.3    Li, J.4    Zurawski, S.M.5    Lo, S.6
  • 4
    • 77951817855 scopus 로고    scopus 로고
    • Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
    • PID: 20200518, COI: 1:CAS:528:DC%2BC3cXivVCiur4%3D
    • Neill DR, Wong SH, Bellosi A, Flynn RJ, Daly M, Langford TK, et al. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature. 2010;464:1367–70.
    • (2010) Nature , vol.464 , pp. 1367-1370
    • Neill, D.R.1    Wong, S.H.2    Bellosi, A.3    Flynn, R.J.4    Daly, M.5    Langford, T.K.6
  • 6
    • 75749122181 scopus 로고    scopus 로고
    • Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells
    • PID: 20023630, COI: 1:CAS:528:DC%2BD1MXhsFyhsL3O
    • Moro K, Yamada T, Tanabe M, Takeuchi T, Ikawa T, Kawamoto H, et al. Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells. Nature. 2010;463:540–4.
    • (2010) Nature , vol.463 , pp. 540-544
    • Moro, K.1    Yamada, T.2    Tanabe, M.3    Takeuchi, T.4    Ikawa, T.5    Kawamoto, H.6
  • 7
    • 84872977452 scopus 로고    scopus 로고
    • Innate lymphoid cells—a proposal for uniform nomenclature
    • PID: 23348417, COI: 1:CAS:528:DC%2BC3sXjslGjtg%3D%3D
    • Spits H, Artis D, Colonna M, Diefenbach A, Di Santo JP, Eberl G, et al. Innate lymphoid cells—a proposal for uniform nomenclature. Nat Rev Immunol. 2013;13:145–9.
    • (2013) Nat Rev Immunol , vol.13 , pp. 145-149
    • Spits, H.1    Artis, D.2    Colonna, M.3    Diefenbach, A.4    Di Santo, J.P.5    Eberl, G.6
  • 8
    • 84877082277 scopus 로고    scopus 로고
    • Development and function of group 2 innate lymphoid cells
    • PID: 23562755, COI: 1:CAS:528:DC%2BC3sXlsVKnt7Y%3D
    • Walker JA, McKenzie AN. Development and function of group 2 innate lymphoid cells. Curr Opin Immunol. 2013;25:148–55.
    • (2013) Curr Opin Immunol , vol.25 , pp. 148-155
    • Walker, J.A.1    McKenzie, A.N.2
  • 9
    • 84907968021 scopus 로고    scopus 로고
    • Development, differentiation, and diversity of innate lymphoid cells
    • PID: 25238093, COI: 1:CAS:528:DC%2BC2cXhsFyhurzJ
    • Diefenbach A, Colonna M, Koyasu S. Development, differentiation, and diversity of innate lymphoid cells. Immunity. 2014;41:354–65.
    • (2014) Immunity , vol.41 , pp. 354-365
    • Diefenbach, A.1    Colonna, M.2    Koyasu, S.3
  • 10
    • 84867164026 scopus 로고    scopus 로고
    • STAT6 regulates natural helper cell proliferation during lung inflammation initiated by Alternaria
    • PID: 22865552, COI: 1:CAS:528:DC%2BC38Xhs1ygtr3J
    • Doherty TA, Khorram N, Chang JE, Kim HK, Rosenthal P, Croft M, et al. STAT6 regulates natural helper cell proliferation during lung inflammation initiated by Alternaria. Am J Physiol Lung Cell Mol Physiol. 2012;303:L577–588.
    • (2012) Am J Physiol Lung Cell Mol Physiol , vol.303 , pp. 577-588
    • Doherty, T.A.1    Khorram, N.2    Chang, J.E.3    Kim, H.K.4    Rosenthal, P.5    Croft, M.6
  • 11
    • 84867773093 scopus 로고    scopus 로고
    • The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells
    • PID: 23063330, Study demonstrating the critical role of transcription factor GATA-3 as an important regulator of human peripheral blood and nasal polyp ILC2 function
    • Mjosberg J, Bernink J, Golebski K, Karrich JJ, Peters CP, Blom B, et al. The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells. Immunity. 2012;37:649–59. Study demonstrating the critical role of transcription factor GATA-3 as an important regulator of human peripheral blood and nasal polyp ILC2 function.
    • (2012) Immunity , vol.37 , pp. 649-659
    • Mjosberg, J.1    Bernink, J.2    Golebski, K.3    Karrich, J.J.4    Peters, C.P.5    Blom, B.6
  • 12
    • 84860343753 scopus 로고    scopus 로고
    • Pulmonary innate lymphoid cells are major producers of IL-5 and IL-13 in murine models of allergic asthma
    • PID: 22539286, Study performed multiple mouse models of asthma to show that ILC2s are major IL-5 and IL-13 producers in the lung compared with other lymphocytes
    • Klein Wolterink RG, Kleinjan A, van Nimwegen M, Bergen I, de Bruijn M, Levani Y, et al. Pulmonary innate lymphoid cells are major producers of IL-5 and IL-13 in murine models of allergic asthma. Eur J Immunol. 2012;42:1106–16. Study performed multiple mouse models of asthma to show that ILC2s are major IL-5 and IL-13 producers in the lung compared with other lymphocytes.
    • (2012) Eur J Immunol , vol.42 , pp. 1106-1116
    • Klein Wolterink, R.G.1    Kleinjan, A.2    van Nimwegen, M.3    Bergen, I.4    de Bruijn, M.5    Levani, Y.6
  • 13
    • 84897402119 scopus 로고    scopus 로고
    • Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells
    • PID: 24388011, COI: 1:CAS:528:DC%2BC2cXivVKnsA%3D%3D
    • Xue L, Salimi M, Panse I, Mjosberg JM, McKenzie AN, Spits H, et al. Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells. J Allergy Clin Immunol. 2014;133:1184–94.
    • (2014) J Allergy Clin Immunol , vol.133 , pp. 1184-1194
    • Xue, L.1    Salimi, M.2    Panse, I.3    Mjosberg, J.M.4    McKenzie, A.N.5    Spits, H.6
  • 14
    • 84882778526 scopus 로고    scopus 로고
    • Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production
    • PID: 23688412, COI: 1:CAS:528:DC%2BC3sXosVGgsLY%3D
    • Doherty TA, Khorram N, Lund S, Mehta AK, Croft M, Broide DH. Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production. J Allergy Clin Immunol. 2013;132:205–13.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 205-213
    • Doherty, T.A.1    Khorram, N.2    Lund, S.3    Mehta, A.K.4    Croft, M.5    Broide, D.H.6
  • 15
    • 84929152818 scopus 로고    scopus 로고
    • At the bench: understanding group 2 innate lymphoid cells in disease
    • PID: 25473099, COI: 1:CAS:528:DC%2BC2MXkvV2gu78%3D
    • Doherty TA. At the bench: understanding group 2 innate lymphoid cells in disease. J Leukoc Biol. 2015;97:455–67.
    • (2015) J Leukoc Biol , vol.97 , pp. 455-467
    • Doherty, T.A.1
  • 16
    • 84954290459 scopus 로고    scopus 로고
    • Group 2 innate lymphoid cells in disease
    • Halim TY. Group 2 innate lymphoid cells in disease. Int Immunol. 2015. doi:10.1093/intimm/dxv050.
    • (2015) Int Immunol
    • Halim, T.Y.1
  • 17
    • 84900830222 scopus 로고    scopus 로고
    • Type 2 innate lymphoid cells in allergic disease
    • PID: 24876829, COI: 1:CAS:528:DC%2BC2cXos1Git70%3D
    • Lund S, Walford HH, Doherty TA. Type 2 innate lymphoid cells in allergic disease. Curr Immunol Rev. 2013;9:214–21.
    • (2013) Curr Immunol Rev , vol.9 , pp. 214-221
    • Lund, S.1    Walford, H.H.2    Doherty, T.A.3
  • 18
    • 84941192964 scopus 로고    scopus 로고
    • Group 2 innate lymphocytes (ILC2) are enriched in active eosinophilic esophagitis
    • PID: 26233928, COI: 1:CAS:528:DC%2BC2MXht1KmtbjF
    • Doherty TA, Baum R, Newbury RO, Yang T, Dohil R, Aquino M, et al. Group 2 innate lymphocytes (ILC2) are enriched in active eosinophilic esophagitis. J Allergy Clin Immunol. 2015;136:792–794.e3.
    • (2015) J Allergy Clin Immunol , vol.136 , pp. 792-794
    • Doherty, T.A.1    Baum, R.2    Newbury, R.O.3    Yang, T.4    Dohil, R.5    Aquino, M.6
  • 19
    • 84953639674 scopus 로고    scopus 로고
    • Smith SG, Chen R, Kjarsgaard M, Huang C, Oliveria JP, O’Byrne PM, et al. Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia. J Allergy Clin Immunol. 2015. The first study demonstrating increased Th2 cytokine producing ILC2s in the airways of patients with severe asthma on systemic corticosteroids
    • Smith SG, Chen R, Kjarsgaard M, Huang C, Oliveria JP, O’Byrne PM, et al. Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia. J Allergy Clin Immunol. 2015. doi:10.1016/j.jaci.2015.05.037. The first study demonstrating increased Th2 cytokine producing ILC2s in the airways of patients with severe asthma on systemic corticosteroids.
  • 20
    • 84957950279 scopus 로고    scopus 로고
    • Nagakumar P, Denney L, Fleming L, Bush A, Lloyd CM, Saglani S, et al. Type 2 innate lymphoid cells in induced sputum from children with severe asthma. J Allergy Clin Immunol. 2015. First report demonstrating ILC2 levels are increased in the sputum of children with severe asthma and providing validation in human airways for ILC2 association with asthma
    • Nagakumar P, Denney L, Fleming L, Bush A, Lloyd CM, Saglani S, et al. Type 2 innate lymphoid cells in induced sputum from children with severe asthma. J Allergy Clin Immunol. 2015. doi:10.1016/j.jaci.2015.06.038. First report demonstrating ILC2 levels are increased in the sputum of children with severe asthma and providing validation in human airways for ILC2 association with asthma.
  • 21
    • 84937022817 scopus 로고    scopus 로고
    • Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33
    • PID: 25617223, COI: 1:CAS:528:DC%2BC2MXhsVantLs%3D
    • Christianson CA, Goplen NP, Zafar I, Irvin C, Good Jr JT, Rollins DR, et al. Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33. J Allergy Clin Immunol. 2015;136(1):59–68.e14.
    • (2015) J Allergy Clin Immunol , vol.136 , Issue.1 , pp. 59-68
    • Christianson, C.A.1    Goplen, N.P.2    Zafar, I.3    Irvin, C.4    Good, J.T.5    Rollins, D.R.6
  • 22
    • 84904665628 scopus 로고    scopus 로고
    • Update on innate lymphoid cells in atopic and non-atopic inflammation in the airways and skin
    • PID: 24912880, COI: 1:STN:280:DC%2BC2cfgsleguw%3D%3D
    • Mjosberg J, Eidsmo L. Update on innate lymphoid cells in atopic and non-atopic inflammation in the airways and skin. Clin Exp Allergy. 2014;44:1033–43.
    • (2014) Clin Exp Allergy , vol.44 , pp. 1033-1043
    • Mjosberg, J.1    Eidsmo, L.2
  • 23
    • 84907983938 scopus 로고    scopus 로고
    • Innate lymphoid cells in inflammation and immunity
    • PID: 25238094, COI: 1:CAS:528:DC%2BC2cXhsFyhurzE
    • McKenzie AN, Spits H, Eberl G. Innate lymphoid cells in inflammation and immunity. Immunity. 2014;41:366–74.
    • (2014) Immunity , vol.41 , pp. 366-374
    • McKenzie, A.N.1    Spits, H.2    Eberl, G.3
  • 24
    • 45449096652 scopus 로고    scopus 로고
    • IL-5 and eosinophilia
    • PID: 18511250, COI: 1:CAS:528:DC%2BD1cXns1ahtrY%3D
    • Takatsu K, Nakajima H. IL-5 and eosinophilia. Curr Opin Immunol. 2008;20:288–94.
    • (2008) Curr Opin Immunol , vol.20 , pp. 288-294
    • Takatsu, K.1    Nakajima, H.2
  • 25
    • 79954501837 scopus 로고    scopus 로고
    • Interleukin-13 signaling and its role in asthma
    • PID: 23283176, COI: 1:CAS:528:DC%2BC38XltFOqsL4%3D
    • Rael EL, Lockey RF. Interleukin-13 signaling and its role in asthma. World Allergy Organ J. 2011;4:54–64.
    • (2011) World Allergy Organ J , vol.4 , pp. 54-64
    • Rael, E.L.1    Lockey, R.F.2
  • 26
    • 84938978427 scopus 로고    scopus 로고
    • IL-4 and IL-13 signaling in allergic airway disease
    • PID: 26070934, COI: 1:CAS:528:DC%2BC2MXpsV2gtL8%3D
    • Gour N, Wills-Karp M. IL-4 and IL-13 signaling in allergic airway disease. Cytokine. 2015;75:68–78.
    • (2015) Cytokine , vol.75 , pp. 68-78
    • Gour, N.1    Wills-Karp, M.2
  • 27
    • 84862615185 scopus 로고    scopus 로고
    • The many lives of IL-9: a question of survival?
    • PID: 22713829, COI: 1:CAS:528:DC%2BC38XovVagtro%3D
    • Wilhelm C, Turner JE, Van Snick J, Stockinger B. The many lives of IL-9: a question of survival? Nat Immunol. 2012;13:637–41.
    • (2012) Nat Immunol , vol.13 , pp. 637-641
    • Wilhelm, C.1    Turner, J.E.2    Van Snick, J.3    Stockinger, B.4
  • 28
    • 84923015891 scopus 로고    scopus 로고
    • Emerging functions of amphiregulin in orchestrating immunity, inflammation, and tissue repair
    • PID: 25692699, COI: 1:CAS:528:DC%2BC2MXjtVSks7g%3D
    • Zaiss DM, Gause WC, Osborne LC, Artis D. Emerging functions of amphiregulin in orchestrating immunity, inflammation, and tissue repair. Immunity. 2015;42:216–26.
    • (2015) Immunity , vol.42 , pp. 216-226
    • Zaiss, D.M.1    Gause, W.C.2    Osborne, L.C.3    Artis, D.4
  • 29
    • 84903604618 scopus 로고    scopus 로고
    • Diagnosis and management of eosinophilic asthma: a US perspective
    • PID: 24748808
    • Walford HH, Doherty TA. Diagnosis and management of eosinophilic asthma: a US perspective. J Asthma Allergy. 2014;7:53–65.
    • (2014) J Asthma Allergy , vol.7 , pp. 53-65
    • Walford, H.H.1    Doherty, T.A.2
  • 30
    • 84860697146 scopus 로고    scopus 로고
    • T cell homing to epithelial barriers in allergic disease
    • PID: 22561834, COI: 1:CAS:528:DC%2BC38XmsFOqsLc%3D
    • Islam SA, Luster AD. T cell homing to epithelial barriers in allergic disease. Nat Med. 2012;18:705–15.
    • (2012) Nat Med , vol.18 , pp. 705-715
    • Islam, S.A.1    Luster, A.D.2
  • 31
    • 84899579332 scopus 로고    scopus 로고
    • TNF superfamily member TL1A elicits type 2 innate lymphoid cells at mucosal barriers
    • PID: 24220298, COI: 1:CAS:528:DC%2BC3sXhslKmsb7L
    • Yu X, Pappu R, Ramirez-Carrozzi V, Ota N, Caplazi P, Zhang J, et al. TNF superfamily member TL1A elicits type 2 innate lymphoid cells at mucosal barriers. Mucosal Immunol. 2014;7:730–40.
    • (2014) Mucosal Immunol , vol.7 , pp. 730-740
    • Yu, X.1    Pappu, R.2    Ramirez-Carrozzi, V.3    Ota, N.4    Caplazi, P.5    Zhang, J.6
  • 32
    • 34248226331 scopus 로고    scopus 로고
    • Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation
    • PID: 17498059, COI: 1:CAS:528:DC%2BD2sXnt1Gmurg%3D
    • Boyce JA. Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation. Immunol Rev. 2007;217:168–85.
    • (2007) Immunol Rev , vol.217 , pp. 168-185
    • Boyce, J.A.1
  • 33
    • 84878592151 scopus 로고    scopus 로고
    • Prostaglandin D(2) pathway upregulation: relation to asthma severity, control, and TH2 inflammation
    • PID: 23506843, COI: 1:CAS:528:DC%2BC3sXktlGlsbs%3D
    • Fajt ML, Gelhaus SL, Freeman B, Uvalle CE, Trudeau JB, Holguin F, et al. Prostaglandin D(2) pathway upregulation: relation to asthma severity, control, and TH2 inflammation. J Allergy Clin Immunol. 2013;131:1504–12.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 1504-1512
    • Fajt, M.L.1    Gelhaus, S.L.2    Freeman, B.3    Uvalle, C.E.4    Trudeau, J.B.5    Holguin, F.6
  • 34
    • 84877923896 scopus 로고    scopus 로고
    • Type 2 innate lymphocytes in allergic airway inflammation
    • PID: 23563812, COI: 1:CAS:528:DC%2BC3sXntlSjtLc%3D
    • Klein Wolterink RG, Hendriks RW. Type 2 innate lymphocytes in allergic airway inflammation. Curr Allergy Asthma Rep. 2013;13:271–80.
    • (2013) Curr Allergy Asthma Rep , vol.13 , pp. 271-280
    • Klein Wolterink, R.G.1    Hendriks, R.W.2
  • 36
    • 84876008998 scopus 로고    scopus 로고
    • Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma
    • Barnig C, Cernadas M, Dutile S, Liu X, Perrella MA, Kazani S, et al. Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma. Sci Transl Med. 2013;5, 174ra126.
    • (2013) Sci Transl Med , vol.5
    • Barnig, C.1    Cernadas, M.2    Dutile, S.3    Liu, X.4    Perrella, M.A.5    Kazani, S.6
  • 37
    • 80052026760 scopus 로고    scopus 로고
    • Role of IL-33 in inflammation and disease
    • COI: 1:CAS:528:DC%2BC3MXht1entbjI
    • Miller AM. Role of IL-33 in inflammation and disease. J Inflamm (Lond). 2011;8:22.
    • (2011) J Inflamm (Lond) , vol.8 , pp. 22
    • Miller, A.M.1
  • 39
    • 75549084963 scopus 로고    scopus 로고
    • Increased expression of IL-33 in severe asthma: evidence of expression by airway smooth muscle cells
    • PID: 19801525, COI: 1:CAS:528:DC%2BD1MXht1WhsbzJ
    • Prefontaine D, Lajoie-Kadoch S, Foley S, Audusseau S, Olivenstein R, Halayko AJ, et al. Increased expression of IL-33 in severe asthma: evidence of expression by airway smooth muscle cells. J Immunol. 2009;183:5094–103.
    • (2009) J Immunol , vol.183 , pp. 5094-5103
    • Prefontaine, D.1    Lajoie-Kadoch, S.2    Foley, S.3    Audusseau, S.4    Olivenstein, R.5    Halayko, A.J.6
  • 40
    • 77957113600 scopus 로고    scopus 로고
    • A large-scale, consortium-based genomewide association study of asthma
    • PID: 20860503, COI: 1:CAS:528:DC%2BC3cXht1Sju73J
    • Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S, et al. A large-scale, consortium-based genomewide association study of asthma. N Engl J Med. 2010;363:1211–21.
    • (2010) N Engl J Med , vol.363 , pp. 1211-1221
    • Moffatt, M.F.1    Gut, I.G.2    Demenais, F.3    Strachan, D.P.4    Bouzigon, E.5    Heath, S.6
  • 41
    • 84926380049 scopus 로고    scopus 로고
    • Increased IL-33 expression in chronic obstructive pulmonary disease
    • PID: 25595648, COI: 1:CAS:528:DC%2BC2MXot12rsrs%3D
    • Xia J, Zhao J, Shang J, Li M, Zeng Z, Zhao J, et al. Increased IL-33 expression in chronic obstructive pulmonary disease. Am J Physiol Lung Cell Mol Physiol. 2015;308:L619–627.
    • (2015) Am J Physiol Lung Cell Mol Physiol , vol.308 , pp. 619-627
    • Xia, J.1    Zhao, J.2    Shang, J.3    Li, M.4    Zeng, Z.5    Zhao, J.6
  • 42
    • 84929735016 scopus 로고    scopus 로고
    • Interleukin-25 and interleukin-33 as mediators of eosinophilic inflammation in chronic rhinosinusitis
    • PID: 25975248
    • Lam M, Hull L, Imrie A, Snidvongs K, Chin D, Pratt E, et al. Interleukin-25 and interleukin-33 as mediators of eosinophilic inflammation in chronic rhinosinusitis. Am J Rhinol Allergy. 2015;29:175–81.
    • (2015) Am J Rhinol Allergy , vol.29 , pp. 175-181
    • Lam, M.1    Hull, L.2    Imrie, A.3    Snidvongs, K.4    Chin, D.5    Pratt, E.6
  • 43
    • 84922974563 scopus 로고    scopus 로고
    • Epithelial cytokines and pulmonary allergic inflammation
    • PID: 25705788, COI: 1:CAS:528:DC%2BC2MXisleqt7Y%3D
    • Lloyd CM, Saglani S. Epithelial cytokines and pulmonary allergic inflammation. Curr Opin Immunol. 2015;34:52–8.
    • (2015) Curr Opin Immunol , vol.34 , pp. 52-58
    • Lloyd, C.M.1    Saglani, S.2
  • 44
    • 84937869139 scopus 로고    scopus 로고
    • Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33
    • PID: 25746970, COI: 1:CAS:528:DC%2BC2MXjvVGnsr8%3D
    • Castanhinha S, Sherburn R, Walker S, Gupta A, Bossley CJ, Buckley J, et al. Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33. J Allergy Clin Immunol. 2015;136:312–322 e317.
    • (2015) J Allergy Clin Immunol , vol.136 , pp. 310-312
    • Castanhinha, S.1    Sherburn, R.2    Walker, S.3    Gupta, A.4    Bossley, C.J.5    Buckley, J.6
  • 45
    • 84920950343 scopus 로고    scopus 로고
    • IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergy
    • PID: 25278425, COI: 1:CAS:528:DC%2BC2cXhs1WjsbfM
    • Cayrol C, Girard JP. IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergy. Curr Opin Immunol. 2014;31:31–7.
    • (2014) Curr Opin Immunol , vol.31 , pp. 31-37
    • Cayrol, C.1    Girard, J.P.2
  • 46
    • 79955040263 scopus 로고    scopus 로고
    • The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses
    • PID: 21357533, COI: 1:CAS:528:DC%2BC3MXjvVKlsrk%3D
    • Kouzaki H, Iijima K, Kobayashi T, O’Grady SM, Kita H. The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses. J Immunol. 2011;186:4375–87.
    • (2011) J Immunol , vol.186 , pp. 4375-4387
    • Kouzaki, H.1    Iijima, K.2    Kobayashi, T.3    O’Grady, S.M.4    Kita, H.5
  • 47
    • 78649884336 scopus 로고    scopus 로고
    • IL-33 family members and asthma—bridging innate and adaptive immune responses
    • PID: 21071194, COI: 1:CAS:528:DC%2BC3cXhsFaqsrnF
    • Lloyd CM. IL-33 family members and asthma—bridging innate and adaptive immune responses. Curr Opin Immunol. 2010;22:800–6.
    • (2010) Curr Opin Immunol , vol.22 , pp. 800-806
    • Lloyd, C.M.1
  • 48
    • 68249143387 scopus 로고    scopus 로고
    • IL-33 raises alarm
    • PID: 19604486, COI: 1:CAS:528:DC%2BD1MXpsFOgtbk%3D
    • Lamkanfi M, Dixit VM. IL-33 raises alarm. Immunity. 2009;31:5–7.
    • (2009) Immunity , vol.31 , pp. 5-7
    • Lamkanfi, M.1    Dixit, V.M.2
  • 49
    • 80054889051 scopus 로고    scopus 로고
    • Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161
    • PID: 21909091
    • Mjosberg JM, Trifari S, Crellin NK, Peters CP, van Drunen CM, Piet B, et al. Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161. Nat Immunol. 2011;12:1055–62.
    • (2011) Nat Immunol , vol.12 , pp. 1055-1062
    • Mjosberg, J.M.1    Trifari, S.2    Crellin, N.K.3    Peters, C.P.4    van Drunen, C.M.5    Piet, B.6
  • 50
    • 79959380307 scopus 로고    scopus 로고
    • Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity
    • PID: 21623379, COI: 1:CAS:528:DC%2BC3MXmslSrt7w%3D
    • Chang YJ, Kim HY, Albacker LA, Baumgarth N, McKenzie AN, Smith DE, et al. Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity. Nat Immunol. 2011;12:631–8.
    • (2011) Nat Immunol , vol.12 , pp. 631-638
    • Chang, Y.J.1    Kim, H.Y.2    Albacker, L.A.3    Baumgarth, N.4    McKenzie, A.N.5    Smith, D.E.6
  • 51
    • 84863011729 scopus 로고    scopus 로고
    • + CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs
    • PID: 22198948, COI: 1:CAS:528:DC%2BC38XpslKmtw%3D%3D
    • + CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs. J Immunol. 2012;188:1503–13.
    • (2012) J Immunol , vol.188 , pp. 1503-1513
    • Bartemes, K.R.1    Iijima, K.2    Kobayashi, T.3    Kephart, G.M.4    McKenzie, A.N.5    Kita, H.6
  • 52
    • 44849117539 scopus 로고    scopus 로고
    • Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system
    • PID: 18448455, COI: 1:CAS:528:DC%2BD1cXmsFOitL8%3D
    • Kondo Y, Yoshimoto T, Yasuda K, Futatsugi-Yumikura S, Morimoto M, Hayashi N, et al. Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system. Int Immunol. 2008;20:791–800.
    • (2008) Int Immunol , vol.20 , pp. 791-800
    • Kondo, Y.1    Yoshimoto, T.2    Yasuda, K.3    Futatsugi-Yumikura, S.4    Morimoto, M.5    Hayashi, N.6
  • 54
    • 79959821549 scopus 로고    scopus 로고
    • Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses
    • PID: 21570719, COI: 1:CAS:528:DC%2BC3MXosFaktbc%3D
    • Corrigan CJ, Wang W, Meng Q, Fang C, Eid G, Caballero MR, et al. Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses. J Allergy Clin Immunol. 2011;128:116–24.
    • (2011) J Allergy Clin Immunol , vol.128 , pp. 116-124
    • Corrigan, C.J.1    Wang, W.2    Meng, Q.3    Fang, C.4    Eid, G.5    Caballero, M.R.6
  • 55
    • 79952136459 scopus 로고    scopus 로고
    • T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma
    • PID: 21205894, COI: 1:CAS:528:DC%2BC3MXhs1Smtb4%3D
    • Corrigan CJ, Wang W, Meng Q, Fang C, Wu H, Reay V, et al. T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma. Proc Natl Acad Sci U S A. 2011;108:1579–84.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 1579-1584
    • Corrigan, C.J.1    Wang, W.2    Meng, Q.3    Fang, C.4    Wu, H.5    Reay, V.6
  • 56
    • 84908374296 scopus 로고    scopus 로고
    • Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation
    • PID: 25273095
    • Beale J, Jayaraman A, Jackson DJ, Macintyre JD, Edwards MR, Walton RP, et al. Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation. Sci Transl Med. 2014;6, 256ra134.
    • (2014) Sci Transl Med , vol.6
    • Beale, J.1    Jayaraman, A.2    Jackson, D.J.3    Macintyre, J.D.4    Edwards, M.R.5    Walton, R.P.6
  • 57
    • 84884905739 scopus 로고    scopus 로고
    • IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction
    • PID: 23810766, COI: 1:CAS:528:DC%2BC3sXhtVKrsLfP
    • Barlow JL, Peel S, Fox J, Panova V, Hardman CS, Camelo A, et al. IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction. J Allergy Clin Immunol. 2013;132:933–41.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 933-941
    • Barlow, J.L.1    Peel, S.2    Fox, J.3    Panova, V.4    Hardman, C.S.5    Camelo, A.6
  • 58
    • 84886630206 scopus 로고    scopus 로고
    • IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells
    • PID: 23960191, COI: 1:CAS:528:DC%2BC3sXhsVSgsbjI
    • Saenz SA, Siracusa MC, Monticelli LA, Ziegler CG, Kim BS, Brestoff JR, et al. IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells. J Exp Med. 2013;210:1823–37.
    • (2013) J Exp Med , vol.210 , pp. 1823-1837
    • Saenz, S.A.1    Siracusa, M.C.2    Monticelli, L.A.3    Ziegler, C.G.4    Kim, B.S.5    Brestoff, J.R.6
  • 59
    • 84864283017 scopus 로고    scopus 로고
    • Functions of thymic stromal lymphopoietin in immunity and disease
    • PID: 22274860, COI: 1:CAS:528:DC%2BC38XntVeitbY%3D
    • Zhang Y, Zhou B. Functions of thymic stromal lymphopoietin in immunity and disease. Immunol Res. 2012;52:211–23.
    • (2012) Immunol Res , vol.52 , pp. 211-223
    • Zhang, Y.1    Zhou, B.2
  • 60
    • 80051570509 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma
    • PID: 20656951, COI: 1:CAS:528:DC%2BC3MXot1Kjtrc%3D
    • Harada M, Hirota T, Jodo AI, Hitomi Y, Sakashita M, Tsunoda T, et al. Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma. Am J Respir Cell Mol Biol. 2011;44:787–93.
    • (2011) Am J Respir Cell Mol Biol , vol.44 , pp. 787-793
    • Harada, M.1    Hirota, T.2    Jodo, A.I.3    Hitomi, Y.4    Sakashita, M.5    Tsunoda, T.6
  • 61
    • 20444365526 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity
    • PID: 15944327, COI: 1:CAS:528:DC%2BD2MXkvVOlsLc%3D
    • Ying S, O’Connor B, Ratoff J, Meng Q, Mallett K, Cousins D, et al. Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity. J Immunol. 2005;174:8183–90.
    • (2005) J Immunol , vol.174 , pp. 8183-8190
    • Ying, S.1    O’Connor, B.2    Ratoff, J.3    Meng, Q.4    Mallett, K.5    Cousins, D.6
  • 62
  • 63
    • 33344455022 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin: master switch for allergic inflammation
    • PID: 16432252
    • Liu YJ. Thymic stromal lymphopoietin: master switch for allergic inflammation. J Exp Med. 2006;203:269–73.
    • (2006) J Exp Med , vol.203 , pp. 269-273
    • Liu, Y.J.1
  • 65
    • 84953284110 scopus 로고    scopus 로고
    • Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis
    • Mohapatra A, Van Dyken SJ, Schneider C, Nussbaum JC, Liang HE, Locksley RM, et al. Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis. Mucosal Immunol. 2015. doi:10.1038/mi.2015.59.
    • (2015) Mucosal Immunol
    • Mohapatra, A.1    Van Dyken, S.J.2    Schneider, C.3    Nussbaum, J.C.4    Liang, H.E.5    Locksley, R.M.6
  • 67
    • 84920973942 scopus 로고    scopus 로고
    • The role of prostaglandins in allergic lung inflammation and asthma
    • PID: 25541289, COI: 1:CAS:528:DC%2BC2MXms1Oktw%3D%3D
    • Claar D, Hartert TV, Peebles Jr RS. The role of prostaglandins in allergic lung inflammation and asthma. Expert Rev Respir Med. 2015;9:55–72.
    • (2015) Expert Rev Respir Med , vol.9 , pp. 55-72
    • Claar, D.1    Hartert, T.V.2    Peebles, R.S.3
  • 68
    • 0025348647 scopus 로고
    • Evidence for elevated levels of histamine, prostaglandin D2, and other bronchoconstricting prostaglandins in the airways of subjects with mild asthma
    • PID: 2368958, COI: 1:STN:280:DyaK3czhsVSksQ%3D%3D
    • Liu MC, Bleecker ER, Lichtenstein LM, Kagey-Sobotka A, Niv Y, McLemore TL, et al. Evidence for elevated levels of histamine, prostaglandin D2, and other bronchoconstricting prostaglandins in the airways of subjects with mild asthma. Am Rev Respir Dis. 1990;142:126–32.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 126-132
    • Liu, M.C.1    Bleecker, E.R.2    Lichtenstein, L.M.3    Kagey-Sobotka, A.4    Niv, Y.5    McLemore, T.L.6
  • 69
    • 0028986360 scopus 로고
    • Prostaglandin D2-induced bronchoconstriction is mediated only in part by the thromboxane prostanoid receptor
    • PID: 7789486, COI: 1:CAS:528:DyaK2MXlsFygtL0%3D
    • Johnston SL, Freezer NJ, Ritter W, O’Toole S, Howarth PH. Prostaglandin D2-induced bronchoconstriction is mediated only in part by the thromboxane prostanoid receptor. Eur Respir J. 1995;8:411–5.
    • (1995) Eur Respir J , vol.8 , pp. 411-415
    • Johnston, S.L.1    Freezer, N.J.2    Ritter, W.3    O’Toole, S.4    Howarth, P.H.5
  • 70
    • 0024548854 scopus 로고
    • Spectrum of prostanoid release after bronchoalveolar allergen challenge in atopic asthmatics and in control groups. An alteration in the ratio of bronchoconstrictive to bronchoprotective mediators
    • PID: 2643903, COI: 1:STN:280:DyaL1M7hs1KrtA%3D%3D
    • Wenzel SE, Westcott JY, Smith HR, Larsen GL. Spectrum of prostanoid release after bronchoalveolar allergen challenge in atopic asthmatics and in control groups. An alteration in the ratio of bronchoconstrictive to bronchoprotective mediators. Am Rev Respir Dis. 1989;139:450–7.
    • (1989) Am Rev Respir Dis , vol.139 , pp. 450-457
    • Wenzel, S.E.1    Westcott, J.Y.2    Smith, H.R.3    Larsen, G.L.4
  • 71
    • 0030756090 scopus 로고    scopus 로고
    • Effect of inhaled prostaglandin D2 in normal and atopic subjects, and of pretreatment with leukotriene D4
    • PID: 9227716, COI: 1:STN:280:DyaK2szntFCqsw%3D%3D
    • Sampson SE, Sampson AP, Costello JF. Effect of inhaled prostaglandin D2 in normal and atopic subjects, and of pretreatment with leukotriene D4. Thorax. 1997;52:513–8.
    • (1997) Thorax , vol.52 , pp. 513-518
    • Sampson, S.E.1    Sampson, A.P.2    Costello, J.F.3
  • 72
    • 84896701743 scopus 로고    scopus 로고
    • Prostaglandin D2 regulates human type 2 innate lymphoid cell chemotaxis
    • PID: 24210841, COI: 1:CAS:528:DC%2BC3sXhsleiu7zL
    • Chang JE, Doherty TA, Baum R, Broide D. Prostaglandin D2 regulates human type 2 innate lymphoid cell chemotaxis. J Allergy Clin Immunol. 2014;133:899–901 e893.
    • (2014) J Allergy Clin Immunol , vol.133 , pp. 890-899
    • Chang, J.E.1    Doherty, T.A.2    Baum, R.3    Broide, D.4
  • 73
    • 3242807236 scopus 로고    scopus 로고
    • Cysteinyl leukotrienes and their receptors: cellular distribution and function in immune and inflammatory responses
    • PID: 15265876, COI: 1:CAS:528:DC%2BD2cXlvVWqu74%3D
    • Kanaoka Y, Boyce JA. Cysteinyl leukotrienes and their receptors: cellular distribution and function in immune and inflammatory responses. J Immunol. 2004;173:1503–10.
    • (2004) J Immunol , vol.173 , pp. 1503-1510
    • Kanaoka, Y.1    Boyce, J.A.2
  • 74
    • 84877019503 scopus 로고    scopus 로고
    • Pathogenesis of aspirin-exacerbated respiratory disease and reactions
    • PID: 23639708
    • Laidlaw TM, Boyce JA. Pathogenesis of aspirin-exacerbated respiratory disease and reactions. Immunol Allergy Clin North Am. 2013;33:195–210.
    • (2013) Immunol Allergy Clin North Am , vol.33 , pp. 195-210
    • Laidlaw, T.M.1    Boyce, J.A.2
  • 75
    • 84903457664 scopus 로고    scopus 로고
    • Cysteinyl leukotrienes and their receptors; emerging concepts
    • PID: 24991451, COI: 1:CAS:528:DC%2BC2cXhsFGhtL7P
    • Kanaoka Y, Boyce JA. Cysteinyl leukotrienes and their receptors; emerging concepts. Allergy Asthma Immunol Res. 2014;6:288–95.
    • (2014) Allergy Asthma Immunol Res , vol.6 , pp. 288-295
    • Kanaoka, Y.1    Boyce, J.A.2
  • 76
    • 51849153327 scopus 로고    scopus 로고
    • Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma
    • PID: 18583575, COI: 1:CAS:528:DC%2BD1cXhtFyht7jI
    • Planaguma A, Kazani S, Marigowda G, Haworth O, Mariani TJ, Israel E, et al. Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma. Am J Respir Crit Care Med. 2008;178:574–82.
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 574-582
    • Planaguma, A.1    Kazani, S.2    Marigowda, G.3    Haworth, O.4    Mariani, T.J.5    Israel, E.6
  • 77
    • 80054868741 scopus 로고    scopus 로고
    • TL1A and DR3, a TNF family ligand-receptor pair that promotes lymphocyte costimulation, mucosal hyperplasia, and autoimmune inflammation
    • PID: 22017439, COI: 1:CAS:528:DC%2BC3MXhsFagsLzJ
    • Meylan F, Richard AC, Siegel RM. TL1A and DR3, a TNF family ligand-receptor pair that promotes lymphocyte costimulation, mucosal hyperplasia, and autoimmune inflammation. Immunol Rev. 2011;244:188–96.
    • (2011) Immunol Rev , vol.244 , pp. 188-196
    • Meylan, F.1    Richard, A.C.2    Siegel, R.M.3
  • 78
    • 84902210026 scopus 로고    scopus 로고
    • The TNF-family cytokine TL1A promotes allergic immunopathology through group 2 innate lymphoid cells
    • PID: 24368564, COI: 1:CAS:528:DC%2BC3sXhvFyltb3M
    • Meylan F, Hawley ET, Barron L, Barlow JL, Penumetcha P, Pelletier M, et al. The TNF-family cytokine TL1A promotes allergic immunopathology through group 2 innate lymphoid cells. Mucosal Immunol. 2014;7:958–68.
    • (2014) Mucosal Immunol , vol.7 , pp. 958-968
    • Meylan, F.1    Hawley, E.T.2    Barron, L.3    Barlow, J.L.4    Penumetcha, P.5    Pelletier, M.6
  • 79
    • 84927650199 scopus 로고    scopus 로고
    • The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells
    • PID: 25786692, COI: 1:CAS:528:DC%2BC2MXlvVejtLk%3D
    • Richard AC, Tan C, Hawley ET, Gomez-Rodriguez J, Goswami R, Yang XP, et al. The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells. J Immunol. 2015;194:3567–82.
    • (2015) J Immunol , vol.194 , pp. 3567-3582
    • Richard, A.C.1    Tan, C.2    Hawley, E.T.3    Gomez-Rodriguez, J.4    Goswami, R.5    Yang, X.P.6
  • 80
    • 84925121085 scopus 로고    scopus 로고
    • ICOS:ICOS-ligand interaction is required for type 2 innate lymphoid cell function, homeostasis, and induction of airway hyperreactivity
    • PID: 25769613, COI: 1:CAS:528:DC%2BC2MXktFeltL0%3D, This study identified a critical role of ICOS/ICOS-L interactions in ILC2 responses in mouse lung inflammation and showed that ILC2 function is regulated through direct contact with other cells via ICOS
    • Maazi H, Patel N, Sankaranarayanan I, Suzuki Y, Rigas D, Soroosh P, et al. ICOS:ICOS-ligand interaction is required for type 2 innate lymphoid cell function, homeostasis, and induction of airway hyperreactivity. Immunity. 2015;42:538–51. This study identified a critical role of ICOS/ICOS-L interactions in ILC2 responses in mouse lung inflammation and showed that ILC2 function is regulated through direct contact with other cells via ICOS.
    • (2015) Immunity , vol.42 , pp. 538-551
    • Maazi, H.1    Patel, N.2    Sankaranarayanan, I.3    Suzuki, Y.4    Rigas, D.5    Soroosh, P.6
  • 81
    • 84943198767 scopus 로고    scopus 로고
    • ICOS regulates the pool of group 2 innate lymphoid cells under homeostatic and inflammatory conditions in mice
    • PID: 26249010, COI: 1:CAS:528:DC%2BC2MXhsVSlurjN
    • Paclik D, Stehle C, Lahmann A, Hutloff A, Romagnani C. ICOS regulates the pool of group 2 innate lymphoid cells under homeostatic and inflammatory conditions in mice. Eur J Immunol. 2015;45:2766–72.
    • (2015) Eur J Immunol , vol.45 , pp. 2766-2772
    • Paclik, D.1    Stehle, C.2    Lahmann, A.3    Hutloff, A.4    Romagnani, C.5
  • 82
    • 84936985235 scopus 로고    scopus 로고
    • ICOS promotes group 2 innate lymphoid cell activation in lungs
    • PID: 26049110, COI: 1:CAS:528:DC%2BC2MXhtVeiu7jI
    • Kamachi F, Isshiki T, Harada N, Akiba H, Miyake S. ICOS promotes group 2 innate lymphoid cell activation in lungs. Biochem Biophys Res Commun. 2015;463:739–45.
    • (2015) Biochem Biophys Res Commun , vol.463 , pp. 739-745
    • Kamachi, F.1    Isshiki, T.2    Harada, N.3    Akiba, H.4    Miyake, S.5
  • 83
    • 33646198059 scopus 로고    scopus 로고
    • Co-stimulatory molecules as potential targets for therapeutic intervention in allergic airway disease
    • PID: 16393317, COI: 1:CAS:528:DC%2BD28Xnt12kug%3D%3D
    • Kallinich T, Beier KC, Gelfand EW, Kroczek RA, Hamelmann E. Co-stimulatory molecules as potential targets for therapeutic intervention in allergic airway disease. Clin Exp Allergy. 2005;35:1521–34.
    • (2005) Clin Exp Allergy , vol.35 , pp. 1521-1534
    • Kallinich, T.1    Beier, K.C.2    Gelfand, E.W.3    Kroczek, R.A.4    Hamelmann, E.5
  • 84
    • 70349421440 scopus 로고    scopus 로고
    • The role of costimulatory molecules in allergic disease and asthma
    • PID: 19786798, COI: 1:CAS:528:DC%2BC3cXitlShtrs%3D
    • Lombardi V, Singh AK, Akbari O. The role of costimulatory molecules in allergic disease and asthma. Int Arch Allergy Immunol. 2010;151:179–89.
    • (2010) Int Arch Allergy Immunol , vol.151 , pp. 179-189
    • Lombardi, V.1    Singh, A.K.2    Akbari, O.3
  • 86
    • 84863418925 scopus 로고    scopus 로고
    • Alternaria induces STAT6-dependent acute airway eosinophilia and epithelial FIZZ1 expression that promotes airway fibrosis and epithelial thickness
    • PID: 22327070, COI: 1:CAS:528:DC%2BC38Xjt1Gntrg%3D
    • Doherty TA, Khorram N, Sugimoto K, Sheppard D, Rosenthal P, Cho JY, et al. Alternaria induces STAT6-dependent acute airway eosinophilia and epithelial FIZZ1 expression that promotes airway fibrosis and epithelial thickness. J Immunol. 2012;188:2622–9.
    • (2012) J Immunol , vol.188 , pp. 2622-2629
    • Doherty, T.A.1    Khorram, N.2    Sugimoto, K.3    Sheppard, D.4    Rosenthal, P.5    Cho, J.Y.6
  • 87
    • 84896847851 scopus 로고    scopus 로고
    • Innate type 2 response to Alternaria extract enhances ryegrass-induced lung inflammation
    • PID: 24296722, COI: 1:CAS:528:DC%2BC2cXivVCrsb0%3D
    • Kim HK, Lund S, Baum R, Rosenthal P, Khorram N, Doherty TA. Innate type 2 response to Alternaria extract enhances ryegrass-induced lung inflammation. Int Arch Allergy Immunol. 2014;163:92–105.
    • (2014) Int Arch Allergy Immunol , vol.163 , pp. 92-105
    • Kim, H.K.1    Lund, S.2    Baum, R.3    Rosenthal, P.4    Khorram, N.5    Doherty, T.A.6
  • 89
    • 59049100417 scopus 로고    scopus 로고
    • Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein
    • PID: 19060881, COI: 1:CAS:528:DC%2BD1MXhtFOmtr8%3D
    • Trompette A, Divanovic S, Visintin A, Blanchard C, Hegde RS, Madan R, et al. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature. 2009;457:585–8.
    • (2009) Nature , vol.457 , pp. 585-588
    • Trompette, A.1    Divanovic, S.2    Visintin, A.3    Blanchard, C.4    Hegde, R.S.5    Madan, R.6
  • 90
    • 64149087970 scopus 로고    scopus 로고
    • House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
    • PID: 19330007, COI: 1:CAS:528:DC%2BD1MXjslartrY%3D
    • Hammad H, Chieppa M, Perros F, Willart MA, Germain RN, Lambrecht BN. House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat Med. 2009;15:410–6.
    • (2009) Nat Med , vol.15 , pp. 410-416
    • Hammad, H.1    Chieppa, M.2    Perros, F.3    Willart, M.A.4    Germain, R.N.5    Lambrecht, B.N.6
  • 91
    • 84897130315 scopus 로고    scopus 로고
    • Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures
    • PID: 24679471, COI: 1:CAS:528:DC%2BC2cXmtVCgur0%3D
    • Gold MJ, Antignano F, Halim TY, Hirota JA, Blanchet MR, Zaph C, et al. Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures. J Allergy Clin Immunol. 2014;133:1142–8.
    • (2014) J Allergy Clin Immunol , vol.133 , pp. 1142-1148
    • Gold, M.J.1    Antignano, F.2    Halim, T.Y.3    Hirota, J.A.4    Blanchet, M.R.5    Zaph, C.6
  • 92
    • 84901052792 scopus 로고    scopus 로고
    • Allergens causing occupational asthma: an evidence-based evaluation of the literature
    • PID: 23595938, COI: 1:CAS:528:DC%2BC2cXntFCrur0%3D
    • Baur X, Bakehe P. Allergens causing occupational asthma: an evidence-based evaluation of the literature. Int Arch Occup Environ Health. 2014;87:339–63.
    • (2014) Int Arch Occup Environ Health , vol.87 , pp. 339-363
    • Baur, X.1    Bakehe, P.2
  • 93
    • 84900397775 scopus 로고    scopus 로고
    • Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation
    • PID: 24837103, COI: 1:CAS:528:DC%2BC2cXosV2ktL8%3D
    • Motomura Y, Morita H, Moro K, Nakae S, Artis D, Endo TA, et al. Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation. Immunity. 2014;40:758–71.
    • (2014) Immunity , vol.40 , pp. 758-771
    • Motomura, Y.1    Morita, H.2    Moro, K.3    Nakae, S.4    Artis, D.5    Endo, T.A.6
  • 94
    • 78649821588 scopus 로고    scopus 로고
    • IL-33 is a crucial amplifier of innate rather than acquired immunity
    • PID: 20937871, COI: 1:CAS:528:DC%2BC3cXhtl2ktrvF
    • Oboki K, Ohno T, Kajiwara N, Arae K, Morita H, Ishii A, et al. IL-33 is a crucial amplifier of innate rather than acquired immunity. Proc Natl Acad Sci U S A. 2010;107:18581–6.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 18581-18586
    • Oboki, K.1    Ohno, T.2    Kajiwara, N.3    Arae, K.4    Morita, H.5    Ishii, A.6
  • 95
    • 84858775590 scopus 로고    scopus 로고
    • Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation
    • PID: 22425247, COI: 1:CAS:528:DC%2BC38XktVaktbk%3D
    • Halim TY, Krauss RH, Sun AC, Takei F. Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation. Immunity. 2012;36:451–63.
    • (2012) Immunity , vol.36 , pp. 451-463
    • Halim, T.Y.1    Krauss, R.H.2    Sun, A.C.3    Takei, F.4
  • 96
    • 84896343916 scopus 로고    scopus 로고
    • Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation
    • PID: 24613091, COI: 1:CAS:528:DC%2BC2cXjslahur4%3D
    • Halim TY, Steer CA, Matha L, Gold MJ, Martinez-Gonzalez I, McNagny KM, et al. Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation. Immunity. 2014;40:425–35.
    • (2014) Immunity , vol.40 , pp. 425-435
    • Halim, T.Y.1    Steer, C.A.2    Matha, L.3    Gold, M.J.4    Martinez-Gonzalez, I.5    McNagny, K.M.6
  • 97
    • 80054927155 scopus 로고    scopus 로고
    • An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation
    • PID: 21983833, COI: 1:CAS:528:DC%2BC3MXht12iu7jE
    • Wilhelm C, Hirota K, Stieglitz B, Van Snick J, Tolaini M, Lahl K, et al. An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation. Nat Immunol. 2011;12:1071–7.
    • (2011) Nat Immunol , vol.12 , pp. 1071-1077
    • Wilhelm, C.1    Hirota, K.2    Stieglitz, B.3    Van Snick, J.4    Tolaini, M.5    Lahl, K.6
  • 98
    • 84937697152 scopus 로고    scopus 로고
    • An interleukin-33-mast cell-interleukin-2 axis suppresses papain-induced allergic inflammation by promoting regulatory T cell numbers
    • PID: 26200013, COI: 1:CAS:528:DC%2BC2MXht1Kiu7nK
    • Morita H, Arae K, Unno H, Miyauchi K, Toyama S, Nambu A, et al. An interleukin-33-mast cell-interleukin-2 axis suppresses papain-induced allergic inflammation by promoting regulatory T cell numbers. Immunity. 2015;43:175–86.
    • (2015) Immunity , vol.43 , pp. 175-186
    • Morita, H.1    Arae, K.2    Unno, H.3    Miyauchi, K.4    Toyama, S.5    Nambu, A.6
  • 99
    • 56149097660 scopus 로고    scopus 로고
    • Viral respiratory infection and the link to asthma
    • PID: 18820588
    • Gern JE. Viral respiratory infection and the link to asthma. Pediatr Infect Dis J. 2008;27:S97–103.
    • (2008) Pediatr Infect Dis J , vol.27 , pp. 97-103
    • Gern, J.E.1
  • 100
    • 84993730732 scopus 로고    scopus 로고
    • Viral infections and the development of asthma in children
    • PID: 25165549
    • Saglani S. Viral infections and the development of asthma in children. Ther Adv Infect Dis. 2013;1:139–50.
    • (2013) Ther Adv Infect Dis , vol.1 , pp. 139-150
    • Saglani, S.1
  • 102
    • 84884683942 scopus 로고    scopus 로고
    • Group 2 innate lymphoid cell production of IL-5 is regulated by NKT cells during influenza virus infection
    • PID: 24068930, COI: 1:CAS:528:DC%2BC3sXhsFOntL3E
    • Gorski SA, Hahn YS, Braciale TJ. Group 2 innate lymphoid cell production of IL-5 is regulated by NKT cells during influenza virus infection. PLoS Pathog. 2013;9, e1003615.
    • (2013) PLoS Pathog , vol.9
    • Gorski, S.A.1    Hahn, Y.S.2    Braciale, T.J.3
  • 103
    • 84983160238 scopus 로고    scopus 로고
    • Pandemic influenza virus, pH1N1, induces asthmatic symptoms via activation of innate lymphoid cells
    • Shim DH, Park YA, Kim MJ, Hong JY, Baek JY, Kim KW, et al. Pandemic influenza virus, pH1N1, induces asthmatic symptoms via activation of innate lymphoid cells. Pediatr Allergy Immunol. 2015. doi:10.1111/pai.12462.
    • (2015) Pediatr Allergy Immunol
    • Shim, D.H.1    Park, Y.A.2    Kim, M.J.3    Hong, J.Y.4    Baek, J.Y.5    Kim, K.W.6
  • 104
    • 85027948313 scopus 로고    scopus 로고
    • Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
    • PID: 21946417, COI: 1:CAS:528:DC%2BC3MXht1anurbP
    • Monticelli LA, Sonnenberg GF, Abt MC, Alenghat T, Ziegler CG, Doering TA, et al. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat Immunol. 2011;12:1045–54.
    • (2011) Nat Immunol , vol.12 , pp. 1045-1054
    • Monticelli, L.A.1    Sonnenberg, G.F.2    Abt, M.C.3    Alenghat, T.4    Ziegler, C.G.5    Doering, T.A.6
  • 105
    • 84905563278 scopus 로고    scopus 로고
    • Neonatal rhinovirus induces mucous metaplasia and airways hyperresponsiveness through IL-25 and type 2 innate lymphoid cells
    • PID: 24910174, COI: 1:CAS:528:DC%2BC2cXpslClsL4%3D
    • Hong JY, Bentley JK, Chung Y, Lei J, Steenrod JM, Chen Q, et al. Neonatal rhinovirus induces mucous metaplasia and airways hyperresponsiveness through IL-25 and type 2 innate lymphoid cells. J Allergy Clin Immunol. 2014;134:429–39.
    • (2014) J Allergy Clin Immunol , vol.134 , pp. 429-439
    • Hong, J.Y.1    Bentley, J.K.2    Chung, Y.3    Lei, J.4    Steenrod, J.M.5    Chen, Q.6
  • 106
    • 84934280461 scopus 로고    scopus 로고
    • Natural helper cells contribute to pulmonary eosinophilia by producing IL-13 via IL-33/ST2 pathway in a murine model of respiratory syncytial virus infection
    • PID: 26044350, COI: 1:CAS:528:DC%2BC2MXpsVylsrg%3D
    • Liu J, Wu J, Qi F, Zeng S, Xu L, Hu H, et al. Natural helper cells contribute to pulmonary eosinophilia by producing IL-13 via IL-33/ST2 pathway in a murine model of respiratory syncytial virus infection. Int Immunopharmacol. 2015;28:337–43.
    • (2015) Int Immunopharmacol , vol.28 , pp. 337-343
    • Liu, J.1    Wu, J.2    Qi, F.3    Zeng, S.4    Xu, L.5    Hu, H.6
  • 107
    • 84919339989 scopus 로고    scopus 로고
    • IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo
    • PID: 25350863, First human study connecting the IL-33/ILC2 axis to rhinovirus-induced asthma exacerbations
    • Jackson DJ, Makrinioti H, Rana BM, Shamji BW, Trujillo-Torralbo MB, Footitt J, et al. IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo. Am J Respir Crit Care Med. 2014;190:1373–82. First human study connecting the IL-33/ILC2 axis to rhinovirus-induced asthma exacerbations.
    • (2014) Am J Respir Crit Care Med , vol.190 , pp. 1373-1382
    • Jackson, D.J.1    Makrinioti, H.2    Rana, B.M.3    Shamji, B.W.4    Trujillo-Torralbo, M.B.5    Footitt, J.6
  • 108
    • 84897426076 scopus 로고    scopus 로고
    • Allergen challenge in allergic rhinitis rapidly induces increased peripheral blood type 2 innate lymphoid cells that express CD84
    • PID: 24582313, COI: 1:CAS:528:DC%2BC2cXjs1Kqu7g%3D, First report to demonstrate a direct correlation between allergen exposure and increased circulating ILC2s in allergic individuals
    • Doherty TA, Scott D, Walford HH, Khorram N, Lund S, Baum R, et al. Allergen challenge in allergic rhinitis rapidly induces increased peripheral blood type 2 innate lymphoid cells that express CD84. J Allergy Clin Immunol. 2014;133:1203–5. First report to demonstrate a direct correlation between allergen exposure and increased circulating ILC2s in allergic individuals.
    • (2014) J Allergy Clin Immunol , vol.133 , pp. 1203-1205
    • Doherty, T.A.1    Scott, D.2    Walford, H.H.3    Khorram, N.4    Lund, S.5    Baum, R.6
  • 109
    • 84913600464 scopus 로고    scopus 로고
    • Seasonal increases in peripheral innate lymphoid type 2 cells are inhibited by subcutaneous grass pollen immunotherapy
    • PID: 25212194
    • Lao-Araya M, Steveling E, Scadding GW, Durham SR, Shamji MH. Seasonal increases in peripheral innate lymphoid type 2 cells are inhibited by subcutaneous grass pollen immunotherapy. J Allergy Clin Immunol. 2014;134:1193–1195 e1194.
    • (2014) J Allergy Clin Immunol , vol.134 , pp. 1190-1193
    • Lao-Araya, M.1    Steveling, E.2    Scadding, G.W.3    Durham, S.R.4    Shamji, M.H.5
  • 110
    • 84906822605 scopus 로고    scopus 로고
    • Enhanced innate type 2 immune response in peripheral blood from patients with asthma
    • PID: 25171868, COI: 1:CAS:528:DC%2BC2cXhsFyrt7%2FL
    • Bartemes KR, Kephart GM, Fox SJ, Kita H. Enhanced innate type 2 immune response in peripheral blood from patients with asthma. J Allergy Clin Immunol. 2014;134:671–678.e4.
    • (2014) J Allergy Clin Immunol , vol.134 , pp. 671-678
    • Bartemes, K.R.1    Kephart, G.M.2    Fox, S.J.3    Kita, H.4
  • 111
    • 84937022817 scopus 로고    scopus 로고
    • Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33
    • PID: 25617223, COI: 1:CAS:528:DC%2BC2MXhsVantLs%3D
    • Christianson CA, Goplen NP, Zafar I, Irvin C, Good Jr JT, Rollins DR, et al. Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33. J Allergy Clin Immunol. 2015;136:59–68 e14.
    • (2015) J Allergy Clin Immunol , vol.136 , pp. 50-59
    • Christianson, C.A.1    Goplen, N.P.2    Zafar, I.3    Irvin, C.4    Good, J.T.5    Rollins, D.R.6
  • 112
    • 84882625503 scopus 로고    scopus 로고
    • IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps
    • PID: 23805875, COI: 1:CAS:528:DC%2BC3sXhsFeqsb7P
    • Shaw JL, Fakhri S, Citardi MJ, Porter PC, Corry DB, Kheradmand F, et al. IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps. Am J Respir Crit Care Med. 2013;188:432–9.
    • (2013) Am J Respir Crit Care Med , vol.188 , pp. 432-439
    • Shaw, J.L.1    Fakhri, S.2    Citardi, M.J.3    Porter, P.C.4    Corry, D.B.5    Kheradmand, F.6
  • 113
    • 84907694433 scopus 로고    scopus 로고
    • Increased ILC2s in the eosinophilic nasal polyp endotype are associated with corticosteroid responsiveness
    • PID: 25236785, COI: 1:CAS:528:DC%2BC2cXhsFyhtr3M
    • Walford HH, Lund SJ, Baum RE, White AA, Bergeron CM, Husseman J, et al. Increased ILC2s in the eosinophilic nasal polyp endotype are associated with corticosteroid responsiveness. Clin Immunol. 2014;155:126–35.
    • (2014) Clin Immunol , vol.155 , pp. 126-135
    • Walford, H.H.1    Lund, S.J.2    Baum, R.E.3    White, A.A.4    Bergeron, C.M.5    Husseman, J.6
  • 114
    • 84905859405 scopus 로고    scopus 로고
    • Association between group 2 innate lymphoid cells enrichment, nasal polyps and allergy in chronic rhinosinusitis
    • PID: 24924975, COI: 1:CAS:528:DC%2BC2cXhtlCltrjN
    • Miljkovic D, Bassiouni A, Cooksley C, Ou J, Hauben E, Wormald PJ, et al. Association between group 2 innate lymphoid cells enrichment, nasal polyps and allergy in chronic rhinosinusitis. Allergy. 2014;69:1154–61.
    • (2014) Allergy , vol.69 , pp. 1154-1161
    • Miljkovic, D.1    Bassiouni, A.2    Cooksley, C.3    Ou, J.4    Hauben, E.5    Wormald, P.J.6
  • 115
    • 84923082670 scopus 로고    scopus 로고
    • Group 2 innate lymphoid cells (ILC2s) are increased in chronic rhinosinusitis with nasal polyps or eosinophilia
    • PID: 25429730, COI: 1:CAS:528:DC%2BC2MXktFaru7s%3D
    • Ho J, Bailey M, Zaunders J, Mrad N, Sacks R, Sewell W, et al. Group 2 innate lymphoid cells (ILC2s) are increased in chronic rhinosinusitis with nasal polyps or eosinophilia. Clin Exp Allergy. 2015;45:394–403.
    • (2015) Clin Exp Allergy , vol.45 , pp. 394-403
    • Ho, J.1    Bailey, M.2    Zaunders, J.3    Mrad, N.4    Sacks, R.5    Sewell, W.6
  • 116
    • 84922273103 scopus 로고    scopus 로고
    • The immunology of asthma
    • PID: 25521684, COI: 1:CAS:528:DC%2BC2cXitFKltL3E
    • Lambrecht BN, Hammad H. The immunology of asthma. Nat Immunol. 2015;16:45–56.
    • (2015) Nat Immunol , vol.16 , pp. 45-56
    • Lambrecht, B.N.1    Hammad, H.2
  • 117
    • 0025284206 scopus 로고
    • Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge
    • PID: 2195930, COI: 1:STN:280:DyaK3czhsVSksw%3D%3D
    • Wenzel SE, Larsen GL, Johnston K, Voelkel NF, Westcott JY. Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge. Am Rev Respir Dis. 1990;142:112–9.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 112-119
    • Wenzel, S.E.1    Larsen, G.L.2    Johnston, K.3    Voelkel, N.F.4    Westcott, J.Y.5
  • 118
    • 84908541933 scopus 로고    scopus 로고
    • Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells
    • PID: 25313073, COI: 1:CAS:528:DC%2BC2cXhslelsbzM
    • Lefrancais E, Duval A, Mirey E, Roga S, Espinosa E, Cayrol C, et al. Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells. Proc Natl Acad Sci U S A. 2014;111:15502–7.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 15502-15507
    • Lefrancais, E.1    Duval, A.2    Mirey, E.3    Roga, S.4    Espinosa, E.5    Cayrol, C.6
  • 119
    • 77957787918 scopus 로고    scopus 로고
    • IL-33 is produced by mast cells and regulates IgE-dependent inflammation
    • PID: 20689814
    • Hsu CL, Neilsen CV, Bryce PJ. IL-33 is produced by mast cells and regulates IgE-dependent inflammation. PLoS ONE. 2010;5, e11944.
    • (2010) PLoS ONE , vol.5
    • Hsu, C.L.1    Neilsen, C.V.2    Bryce, P.J.3
  • 120
    • 84878538890 scopus 로고    scopus 로고
    • Endotypes and phenotypes of chronic rhinosinusitis: a PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology
    • PID: 23587334
    • Akdis CA, Bachert C, Cingi C, Dykewicz MS, Hellings PW, Naclerio RM, et al. Endotypes and phenotypes of chronic rhinosinusitis: a PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol. 2013;131:1479–90.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 1479-1490
    • Akdis, C.A.1    Bachert, C.2    Cingi, C.3    Dykewicz, M.S.4    Hellings, P.W.5    Naclerio, R.M.6
  • 121
    • 84969169828 scopus 로고    scopus 로고
    • Five-year risk of incident disease following a diagnosis of chronic rhinosinusitis
    • Hirsch AG, Yan X, Sundaresan A, Tan BK, Schleimer RP, Kern RC, et al. Five-year risk of incident disease following a diagnosis of chronic rhinosinusitis. Allergy. 2015;70:1613–21.
    • (2015) Allergy , vol.70 , pp. 1613-1621
    • Hirsch, A.G.1    Yan, X.2    Sundaresan, A.3    Tan, B.K.4    Schleimer, R.P.5    Kern, R.C.6
  • 122
    • 84896849811 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation
    • PID: 24157859
    • Kabata H, Moro K, Fukunaga K, Suzuki Y, Miyata J, Masaki K, et al. Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation. Nat Commun. 2013;4:2675.
    • (2013) Nat Commun , vol.4 , pp. 2675
    • Kabata, H.1    Moro, K.2    Fukunaga, K.3    Suzuki, Y.4    Miyata, J.5    Masaki, K.6
  • 124
    • 84883547818 scopus 로고    scopus 로고
    • Innate type 2 immunity is associated with eosinophilic pleural effusion in primary spontaneous pneumothorax
    • PID: 23815597, COI: 1:CAS:528:DC%2BC3sXhs1Wgt7%2FE
    • Kwon BI, Hong S, Shin K, Choi EH, Hwang JJ, Lee SH. Innate type 2 immunity is associated with eosinophilic pleural effusion in primary spontaneous pneumothorax. Am J Respir Crit Care Med. 2013;188:577–85.
    • (2013) Am J Respir Crit Care Med , vol.188 , pp. 577-585
    • Kwon, B.I.1    Hong, S.2    Shin, K.3    Choi, E.H.4    Hwang, J.J.5    Lee, S.H.6


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