Neonatal rhinovirus induces mucous metaplasia and airways hyperresponsiveness through IL-25 and type 2 innate lymphoid cells

Journal of Allergy and Clinical Immunology

Volumn 134, Issue 2, 2014, Pages

  Hong, Jun Young ^a   Bentley, J Kelley ^a   Chung, Yutein ^a   Lei, Jing ^a   Steenrod, Jessica M ^a   Chen, Qiang ^a   Sajjan, Uma S ^a   Hershenson, Marc B ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Asthma; IL 25; mouse; neonatal; rhinovirus; type 2 innate lymphoid cells

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR 1; GOB5 PROTEIN; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 25; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 7 RECEPTOR; METHACHOLINE; MUCIN 5AC; MUCIN 5B; NEUTRALIZING ANTIBODY; PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; D17WSU104E PROTEIN, MOUSE; INTERLEUKIN DERIVATIVE;

ADULT; AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD25+ CD127+ T LYMPHOCYTE; CD25+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN RHINOVIRUS; INNATE IMMUNITY; METAPLASIA; MOUSE; NEWBORN; NEWBORN INFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY TRACT ALLERGY; RHINOVIRUS INFECTION; T LYMPHOCYTE SUBPOPULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CHILD; COMPLICATION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGY; LUNG; LYMPHOCYTE; MUCUS; PATHOLOGY; PICORNAVIRUS INFECTION; RHINOVIRUS; SIGNAL TRANSDUCTION;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, NEUTRALIZING; CELL PROLIFERATION; CHILD; GENE EXPRESSION REGULATION; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-12 SUBUNIT P40; INTERLEUKIN-13; INTERLEUKINS; LUNG; LYMPHOCYTES; MICE; MUCUS; PICORNAVIRIDAE INFECTIONS; RESPIRATORY HYPERSENSITIVITY; RHINOVIRUS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84905563278     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.04.020     Document Type: Article

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