Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia

Journal of Allergy and Clinical Immunology

Volumn 137, Issue 1, 2016, Pages 75-86.e8

  Smith, Steven G ^a   Chen, Ruchong ^a,b   Kjarsgaard, Melanie ^a   Huang, Chynna ^a   Oliveria, John Paul ^a   O'Byrne, Paul M ^a   Gauvreau, Gail M ^a   Boulet, Louis Philippe ^c   Lemiere, Catherine ^d   Martin, James ^e   Nair, Parameswaran ^a   Sehmi, Roma ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

^c LAVAL UNIVERSITY   (Canada)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

^e MCGILL UNIVERSITY   (Canada)

Author keywords

eosinophilic bronchitis; Group 2 innate lymphoid cells; severe asthma

Indexed keywords

CD34 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; INTERLEUKIN 13; INTERLEUKIN 5; INTERLEUKIN 5 RECEPTOR ALPHA; INTERLEUKIN 7 RECEPTOR; PREDNISONE; IL5 PROTEIN, HUMAN; INTERLEUKIN-13, HUMAN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; CELL ISOLATION; CONTROLLED STUDY; CORTICOSTEROID THERAPY; CROSS-SECTIONAL STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; DRUG DOSE REDUCTION; DRUG MEGADOSE; EOSINOPHILIA; FLOW CYTOMETRY; FORCED EXPIRATORY VOLUME; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNOFLUORESCENCE; IN VIVO STUDY; INFLAMMATION; LYMPHOID CELL; MOUSE; MOUSE MODEL; NONHUMAN; PERSISTENT AIRWAY EOSINOPHILIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPUTUM; STEROID NAIVE MILD ATOPIC ASTHMA; T LYMPHOCYTE; BLOOD; CYTOLOGY; FEMALE; IMMUNOLOGY; INNATE IMMUNITY; LOEFFLER PNEUMONIA; LYMPHOCYTE; MALE; MIDDLE AGED; YOUNG ADULT;

ADULT; ASTHMA; FEMALE; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-13; INTERLEUKIN-5; LYMPHOCYTES; MALE; MIDDLE AGED; PULMONARY EOSINOPHILIA; SPUTUM; YOUNG ADULT;

EID: 84953639674     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.05.037     Document Type: Article

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