-
1
-
-
84896709653
-
Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects
-
PID: 24239664
-
Ben-Shlomo Y, Spears M, Boustred C, May M, Anderson SG, Benjamin EJ, et al. Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects. J Am Coll Cardiol. 2014;63(7):636–46. doi:10.1016/j.jacc.2013.09.063.
-
(2014)
J Am Coll Cardiol
, vol.63
, Issue.7
, pp. 636-646
-
-
Ben-Shlomo, Y.1
Spears, M.2
Boustred, C.3
May, M.4
Anderson, S.G.5
Benjamin, E.J.6
-
2
-
-
84908697888
-
Inflammation and arterial stiffness in humans
-
PID: 25463062
-
Jain S, Khera R, Corrales-Medina VF, Townsend RR, Chirinos JA. Inflammation and arterial stiffness in humans. Atherosclerosis. 2014;237(2):381–90. doi:10.1016/j.atherosclerosis.2014.09.011.
-
(2014)
Atherosclerosis
, vol.237
, Issue.2
, pp. 381-390
-
-
Jain, S.1
Khera, R.2
Corrales-Medina, V.F.3
Townsend, R.R.4
Chirinos, J.A.5
-
3
-
-
84904514598
-
Arterial stiffness and hypertension: chicken or egg?
-
PID: 24799614
-
Mitchell GF. Arterial stiffness and hypertension: chicken or egg? Hypertension. 2014;64(2):210–4. doi:10.1161/HYPERTENSIONAHA.114.03449.
-
(2014)
Hypertension
, vol.64
, Issue.2
, pp. 210-214
-
-
Mitchell, G.F.1
-
4
-
-
76349084693
-
Arterial stiffness and cardiovascular events: the Framingham Heart Study
-
PID: 20083680, Clinical study establishing role of vascular stiffness in cardiovascular outcomes
-
Mitchell GF, Hwang SJ, Vasan RS, Larson MG, Pencina MJ, Hamburg NM, et al. Arterial stiffness and cardiovascular events: the Framingham Heart Study. Circulation. 2010;121(4):505–11. doi:10.1161/CIRCULATIONAHA.109.886655. Clinical study establishing role of vascular stiffness in cardiovascular outcomes.
-
(2010)
Circulation
, vol.121
, Issue.4
, pp. 505-511
-
-
Mitchell, G.F.1
Hwang, S.J.2
Vasan, R.S.3
Larson, M.G.4
Pencina, M.J.5
Hamburg, N.M.6
-
5
-
-
81055144033
-
Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility—Reykjavik study
-
PID: 22075523
-
Mitchell GF, van Buchem MA, Sigurdsson S, Gotal JD, Jonsdottir MK, Kjartansson O, et al. Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility—Reykjavik study. Brain. 2011;134(Pt 11):3398–407. doi:10.1093/brain/awr253.
-
(2011)
Brain
, vol.134
, pp. 3398-3407
-
-
Mitchell, G.F.1
van Buchem, M.A.2
Sigurdsson, S.3
Gotal, J.D.4
Jonsdottir, M.K.5
Kjartansson, O.6
-
6
-
-
0026689951
-
Effect of reduced aortic compliance on cardiac efficiency and contractile function of in situ canine left ventricle
-
PID: 1386792
-
Kelly RP, Tunin R, Kass DA. Effect of reduced aortic compliance on cardiac efficiency and contractile function of in situ canine left ventricle. Circ Res. 1992;71(3):490–502.
-
(1992)
Circ Res
, vol.71
, Issue.3
, pp. 490-502
-
-
Kelly, R.P.1
Tunin, R.2
Kass, D.A.3
-
7
-
-
21744459081
-
Relationship between aortic stiffening and microvascular disease in brain and kidney: cause and logic of therapy
-
PID: 15911742
-
O'Rourke MF, Safar ME. Relationship between aortic stiffening and microvascular disease in brain and kidney: cause and logic of therapy. Hypertension. 2005;46(1):200–4. doi:10.1161/01.HYP.0000168052.00426.65.
-
(2005)
Hypertension
, vol.46
, Issue.1
, pp. 200-204
-
-
O'Rourke, M.F.1
Safar, M.E.2
-
8
-
-
84861960142
-
Pulmonary vascular stiffness: measurement, modeling, and implications in normal and hypertensive pulmonary circulations
-
Overviews the role of pulmonary stiffness in PH pathophysiology
-
Hunter KS, Lammers SR, Shandas R. Pulmonary vascular stiffness: measurement, modeling, and implications in normal and hypertensive pulmonary circulations. Comp Physiol. 2011;1(3):1413–35. doi:10.1002/cphy.c100005. Overviews the role of pulmonary stiffness in PH pathophysiology.
-
(2011)
Comp Physiol
, vol.1
, Issue.3
, pp. 1413-1435
-
-
Hunter, K.S.1
Lammers, S.R.2
Shandas, R.3
-
9
-
-
84861998879
-
Mechanics and function of the pulmonary vasculature: implications for pulmonary vascular disease and right ventricular function
-
Discusses physiologic and pathologic aspects of the RV-PA axis as a mechanically coupled unit
-
Lammers S, Scott D, Hunter K, Tan W, Shandas R, Stenmark KR. Mechanics and function of the pulmonary vasculature: implications for pulmonary vascular disease and right ventricular function. Comp Physiol. 2012;2(1):295–319. doi:10.1002/cphy.c100070. Discusses physiologic and pathologic aspects of the RV-PA axis as a mechanically coupled unit.
-
(2012)
Comp Physiol
, vol.2
, Issue.1
, pp. 295-319
-
-
Lammers, S.1
Scott, D.2
Hunter, K.3
Tan, W.4
Shandas, R.5
Stenmark, K.R.6
-
10
-
-
85026338317
-
Vascular stiffening in pulmonary hypertension: cause or consequence? (2013 Grover Conference series)
-
PID: 25610594
-
Tan W, Madhavan K, Hunter KS, Park D, Stenmark KR. Vascular stiffening in pulmonary hypertension: cause or consequence? (2013 Grover Conference series). Pulm Circ. 2014;4(4):560–80. doi:10.1086/677370.
-
(2014)
Pulm Circ
, vol.4
, Issue.4
, pp. 560-580
-
-
Tan, W.1
Madhavan, K.2
Hunter, K.S.3
Park, D.4
Stenmark, K.R.5
-
11
-
-
36849011710
-
Pulmonary vascular input impedance is a combined measure of pulmonary vascular resistance and stiffness and predicts clinical outcomes better than pulmonary vascular resistance alone in pediatric patients with pulmonary hypertension
-
PID: 18082509, Important validation of impedance measurement as PH prognostic indicator
-
Hunter KS, Lee PF, Lanning CJ, Ivy DD, Kirby KS, Claussen LR, et al. Pulmonary vascular input impedance is a combined measure of pulmonary vascular resistance and stiffness and predicts clinical outcomes better than pulmonary vascular resistance alone in pediatric patients with pulmonary hypertension. Am Heart J. 2008;155(1):166–74. doi:10.1016/j.ahj.2007.08.014. Important validation of impedance measurement as PH prognostic indicator.
-
(2008)
Am Heart J
, vol.155
, Issue.1
, pp. 166-174
-
-
Hunter, K.S.1
Lee, P.F.2
Lanning, C.J.3
Ivy, D.D.4
Kirby, K.S.5
Claussen, L.R.6
-
12
-
-
71949129187
-
Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure
-
PID: 19748998
-
Stenmark KR, Meyrick B, Galie N, Mooi WJ, McMurtry IF. Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure. Am J Physiol Lung Cell Mol Physiol. 2009;297(6):L1013–32. doi:10.1152/ajplung.00217.2009.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
, Issue.6
, pp. L1013-L1032
-
-
Stenmark, K.R.1
Meyrick, B.2
Galie, N.3
Mooi, W.J.4
McMurtry, I.F.5
-
13
-
-
84859572506
-
RV dysfunction in pulmonary hypertension is independently related to pulmonary artery stiffness
-
PID: 22498327
-
Stevens GR, Garcia-Alvarez A, Sahni S, Garcia MJ, Fuster V, Sanz J. RV dysfunction in pulmonary hypertension is independently related to pulmonary artery stiffness. JACC Cardiovasc Imaging. 2012;5(4):378–87. doi:10.1016/j.jcmg.2011.11.020.
-
(2012)
JACC Cardiovasc Imaging
, vol.5
, Issue.4
, pp. 378-387
-
-
Stevens, G.R.1
Garcia-Alvarez, A.2
Sahni, S.3
Garcia, M.J.4
Fuster, V.5
Sanz, J.6
-
14
-
-
37549020328
-
Noninvasively assessed pulmonary artery stiffness predicts mortality in pulmonary arterial hypertension
-
PID: 17989161
-
Gan CT, Lankhaar JW, Westerhof N, Marcus JT, Becker A, Twisk JW, et al. Noninvasively assessed pulmonary artery stiffness predicts mortality in pulmonary arterial hypertension. Chest. 2007;132(6):1906–12. doi:10.1378/chest.07-1246.
-
(2007)
Chest
, vol.132
, Issue.6
, pp. 1906-1912
-
-
Gan, C.T.1
Lankhaar, J.W.2
Westerhof, N.3
Marcus, J.T.4
Becker, A.5
Twisk, J.W.6
-
15
-
-
61649125621
-
Evaluation of pulmonary artery stiffness in pulmonary hypertension with cardiac magnetic resonance
-
PID: 19356573
-
Sanz J, Kariisa M, Dellegrottaglie S, Prat-Gonzalez S, Garcia MJ, Fuster V, et al. Evaluation of pulmonary artery stiffness in pulmonary hypertension with cardiac magnetic resonance. JACC Cardiovasc Imaging. 2009;2(3):286–95. doi:10.1016/j.jcmg.2008.08.007.
-
(2009)
JACC Cardiovasc Imaging
, vol.2
, Issue.3
, pp. 286-295
-
-
Sanz, J.1
Kariisa, M.2
Dellegrottaglie, S.3
Prat-Gonzalez, S.4
Garcia, M.J.5
Fuster, V.6
-
16
-
-
84865988470
-
Pulmonary vascular wall stiffness: an important contributor to the increased right ventricular afterload with pulmonary hypertension
-
PID: 22034607
-
Wang Z, Chesler NC. Pulmonary vascular wall stiffness: an important contributor to the increased right ventricular afterload with pulmonary hypertension. Pulm Circ. 2011;1(2):212–23. doi:10.4103/2045-8932.83453.
-
(2011)
Pulm Circ
, vol.1
, Issue.2
, pp. 212-223
-
-
Wang, Z.1
Chesler, N.C.2
-
17
-
-
33750074997
-
The current treatment of pulmonary arterial hypertension: time to redefine success
-
PID: 17035456
-
Rich S. The current treatment of pulmonary arterial hypertension: time to redefine success. Chest. 2006;130(4):1198–202. doi:10.1378/chest.130.4.1198.
-
(2006)
Chest
, vol.130
, Issue.4
, pp. 1198-1202
-
-
Rich, S.1
-
18
-
-
34249294002
-
The value of approved therapies for pulmonary arterial hypertension
-
PID: 17540187
-
Rich S. The value of approved therapies for pulmonary arterial hypertension. Am Heart J. 2007;153(6):889–90. doi:10.1016/j.ahj.2007.03.001.
-
(2007)
Am Heart J
, vol.153
, Issue.6
, pp. 889-890
-
-
Rich, S.1
-
19
-
-
34249302372
-
A meta-analysis of trials of pulmonary hypertension: a clinical condition looking for drugs and research methodology
-
PID: 17540207
-
Macchia A, Marchioli R, Marfisi R, Scarano M, Levantesi G, Tavazzi L, et al. A meta-analysis of trials of pulmonary hypertension: a clinical condition looking for drugs and research methodology. Am Heart J. 2007;153(6):1037–47. doi:10.1016/j.ahj.2007.02.037.
-
(2007)
Am Heart J
, vol.153
, Issue.6
, pp. 1037-1047
-
-
Macchia, A.1
Marchioli, R.2
Marfisi, R.3
Scarano, M.4
Levantesi, G.5
Tavazzi, L.6
-
20
-
-
84865844525
-
Elastin in large artery stiffness and hypertension
-
PID: 22290157
-
Wagenseil JE, Mecham RP. Elastin in large artery stiffness and hypertension. J Cardiovasc Transl Res. 2012;5(3):264–73. doi:10.1007/s12265-012-9349-8.
-
(2012)
J Cardiovasc Transl Res
, vol.5
, Issue.3
, pp. 264-273
-
-
Wagenseil, J.E.1
Mecham, R.P.2
-
21
-
-
84877255785
-
Elastin and collagen fibre microstructure of the human aorta in ageing and disease: a review
-
PID: 23536538
-
Tsamis A, Krawiec JT, Vorp DA. Elastin and collagen fibre microstructure of the human aorta in ageing and disease: a review. J R Soc Interface. 2013;10(83):20121004. doi:10.1098/rsif.2012.1004.
-
(2013)
J R Soc Interface
, vol.10
, Issue.83
, pp. 20121004
-
-
Tsamis, A.1
Krawiec, J.T.2
Vorp, D.A.3
-
22
-
-
2942574709
-
Pathologic assessment of vasculopathies in pulmonary hypertension
-
PID: 15194175
-
Pietra GG, Capron F, Stewart S, Leone O, Humbert M, Robbins IM, et al. Pathologic assessment of vasculopathies in pulmonary hypertension. J Am Coll Cardiol. 2004;43(12 Suppl S):25S–32. doi:10.1016/j.jacc.2004.02.033.
-
(2004)
J Am Coll Cardiol
, vol.43
, pp. 25S-32
-
-
Pietra, G.G.1
Capron, F.2
Stewart, S.3
Leone, O.4
Humbert, M.5
Robbins, I.M.6
-
23
-
-
84890753066
-
Relevant issues in the pathology and pathobiology of pulmonary hypertension
-
PID: 24355640
-
Tuder RM, Archer SL, Dorfmuller P, Erzurum SC, Guignabert C, Michelakis E, et al. Relevant issues in the pathology and pathobiology of pulmonary hypertension. J Am Coll Cardiol. 2013;62(25 Suppl):D4–12. doi:10.1016/j.jacc.2013.10.025.
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. D4-D12
-
-
Tuder, R.M.1
Archer, S.L.2
Dorfmuller, P.3
Erzurum, S.C.4
Guignabert, C.5
Michelakis, E.6
-
24
-
-
33749345684
-
Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms
-
PID: 17008597
-
Stenmark KR, Fagan KA, Frid MG. Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms. Circ Res. 2006;99(7):675–91. doi:10.1161/01.RES.0000243584.45145.3f.
-
(2006)
Circ Res
, vol.99
, Issue.7
, pp. 675-691
-
-
Stenmark, K.R.1
Fagan, K.A.2
Frid, M.G.3
-
25
-
-
84920508612
-
4D flow imaging with MRI
-
PID: 24834414
-
Stankovic Z, Allen BD, Garcia J, Jarvis KB, Markl M. 4D flow imaging with MRI. Cardiovasc Diagn Ther. 2014;4(2):173–92. doi:10.3978/j.issn.2223-3652.2014.01.02.
-
(2014)
Cardiovasc Diagn Ther
, vol.4
, Issue.2
, pp. 173-192
-
-
Stankovic, Z.1
Allen, B.D.2
Garcia, J.3
Jarvis, K.B.4
Markl, M.5
-
26
-
-
73449123684
-
A comprehensive histopathological evaluation of vascular medial fibrosis: insights into the pathophysiology of arterial stiffening
-
PID: 19632677
-
Selvin E, Najjar SS, Cornish TC, Halushka MK. A comprehensive histopathological evaluation of vascular medial fibrosis: insights into the pathophysiology of arterial stiffening. Atherosclerosis. 2010;208(1):69–74. doi:10.1016/j.atherosclerosis.2009.06.025.
-
(2010)
Atherosclerosis
, vol.208
, Issue.1
, pp. 69-74
-
-
Selvin, E.1
Najjar, S.S.2
Cornish, T.C.3
Halushka, M.K.4
-
27
-
-
84924245104
-
Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell disease and severe pulmonary arterial hypertension
-
PID: 25006410
-
Rogers NM, Yao M, Sembrat J, George MP, Knupp H, Ross M, et al. Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell disease and severe pulmonary arterial hypertension. Pulm Circ. 2013;3(4):936–51. doi:10.1086/674754.
-
(2013)
Pulm Circ
, vol.3
, Issue.4
, pp. 936-951
-
-
Rogers, N.M.1
Yao, M.2
Sembrat, J.3
George, M.P.4
Knupp, H.5
Ross, M.6
-
28
-
-
57049137815
-
Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves
-
PID: 18660454
-
Lammers SR, Kao PH, Qi HJ, Hunter K, Lanning C, Albietz J, et al. Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves. Am J Physiol Heart Circ Physiol. 2008;295(4):H1451–9. doi:10.1152/ajpheart.00127.2008.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
, Issue.4
, pp. H1451-H1459
-
-
Lammers, S.R.1
Kao, P.H.2
Qi, H.J.3
Hunter, K.4
Lanning, C.5
Albietz, J.6
-
29
-
-
16244411295
-
Overexpression of hyaluronan in the tunica media promotes the development of atherosclerosis
-
PID: 15705963
-
Chai S, Chai Q, Danielsen CC, Hjorth P, Nyengaard JR, Ledet T, et al. Overexpression of hyaluronan in the tunica media promotes the development of atherosclerosis. Circ Res. 2005;96(5):583–91. doi:10.1161/01.RES.0000158963.37132.8b.
-
(2005)
Circ Res
, vol.96
, Issue.5
, pp. 583-591
-
-
Chai, S.1
Chai, Q.2
Danielsen, C.C.3
Hjorth, P.4
Nyengaard, J.R.5
Ledet, T.6
-
30
-
-
42049109939
-
Vascular stiffness is related to superoxide generation in the vessel wall
-
PID: 18398337
-
Delles C, Zimmerli LU, McGrane DJ, Koh-Tan CH, Pathi VL, McKay AJ, et al. Vascular stiffness is related to superoxide generation in the vessel wall. J Hypertens. 2008;26(5):946–55. doi:10.1097/HJH.0b013e3282f7677c.
-
(2008)
J Hypertens
, vol.26
, Issue.5
, pp. 946-955
-
-
Delles, C.1
Zimmerli, L.U.2
McGrane, D.J.3
Koh-Tan, C.H.4
Pathi, V.L.5
McKay, A.J.6
-
31
-
-
10544246489
-
Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability
-
PID: 8958220
-
Rajagopalan S, Meng XP, Ramasamy S, Harrison DG, Galis ZS. Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability. J Clin Invest. 1996;98(11):2572–9. doi:10.1172/JCI119076.
-
(1996)
J Clin Invest
, vol.98
, Issue.11
, pp. 2572-2579
-
-
Rajagopalan, S.1
Meng, X.P.2
Ramasamy, S.3
Harrison, D.G.4
Galis, Z.S.5
-
32
-
-
18244373458
-
Mechanisms, pathophysiology, and therapy of arterial stiffness
-
PID: 15731494
-
Zieman SJ, Melenovsky V, Kass DA. Mechanisms, pathophysiology, and therapy of arterial stiffness. Arterioscler Thromb Vasc Biol. 2005;25(5):932–43. doi:10.1161/01.ATV.0000160548.78317.29.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, Issue.5
, pp. 932-943
-
-
Zieman, S.J.1
Melenovsky, V.2
Kass, D.A.3
-
33
-
-
0037155057
-
Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly
-
PID: 11861412
-
Galis ZS, Khatri JJ. Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly. Circ Res. 2002;90(3):251–62.
-
(2002)
Circ Res
, vol.90
, Issue.3
, pp. 251-262
-
-
Galis, Z.S.1
Khatri, J.J.2
-
34
-
-
84870394970
-
Molecular mechanisms of arterial stiffness: new insights
-
PID: 23199674
-
Luft FC. Molecular mechanisms of arterial stiffness: new insights. J Am Soc Hypertens. 2012;6(6):436–8. doi:10.1016/j.jash.2012.10.004.
-
(2012)
J Am Soc Hypertens
, vol.6
, Issue.6
, pp. 436-438
-
-
Luft, F.C.1
-
35
-
-
0022853501
-
Pulmonary artery endothelial abnormalities in patients with congenital heart defects and pulmonary hypertension. A correlation of light with scanning electron microscopy and transmission electron microscopy
-
PID: 3784535
-
Rabinovitch M, Bothwell T, Hayakawa BN, Williams WG, Trusler GA, Rowe RD, et al. Pulmonary artery endothelial abnormalities in patients with congenital heart defects and pulmonary hypertension. A correlation of light with scanning electron microscopy and transmission electron microscopy. Lab Invest. 1986;55(6):632–53.
-
(1986)
Lab Invest
, vol.55
, Issue.6
, pp. 632-653
-
-
Rabinovitch, M.1
Bothwell, T.2
Hayakawa, B.N.3
Williams, W.G.4
Trusler, G.A.5
Rowe, R.D.6
-
36
-
-
84894499335
-
Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase
-
PID: 24347665
-
Wu J, Thabet SR, Kirabo A, Trott DW, Saleh MA, Xiao L, et al. Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase. Circ Res. 2014;114(4):616–25. doi:10.1161/CIRCRESAHA.114.302157.
-
(2014)
Circ Res
, vol.114
, Issue.4
, pp. 616-625
-
-
Wu, J.1
Thabet, S.R.2
Kirabo, A.3
Trott, D.W.4
Saleh, M.A.5
Xiao, L.6
-
37
-
-
79451475690
-
Critical roles of macrophages in the formation of intracranial aneurysm
-
PID: 21106959
-
Kanematsu Y, Kanematsu M, Kurihara C, Tada Y, Tsou TL, van Rooijen N, et al. Critical roles of macrophages in the formation of intracranial aneurysm. Stroke. 2011;42(1):173–8. doi:10.1161/STROKEAHA.110.590976.
-
(2011)
Stroke
, vol.42
, Issue.1
, pp. 173-178
-
-
Kanematsu, Y.1
Kanematsu, M.2
Kurihara, C.3
Tada, Y.4
Tsou, T.L.5
van Rooijen, N.6
-
38
-
-
77956244520
-
CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses
-
PID: 20733031
-
Zhou J, Tang PC, Qin L, Gayed PM, Li W, Skokos EA, et al. CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses. J Exp Med. 2010;207(9):1951–66. doi:10.1084/jem.20100098.
-
(2010)
J Exp Med
, vol.207
, Issue.9
, pp. 1951-1966
-
-
Zhou, J.1
Tang, P.C.2
Qin, L.3
Gayed, P.M.4
Li, W.5
Skokos, E.A.6
-
39
-
-
33144471139
-
Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage
-
PID: 16436679, Significant earlier paper demonstrating recruitment of circulating inflammatory cells to the vessel wall as determinant of remodeling in PH
-
Frid MG, Brunetti JA, Burke DL, Carpenter TC, Davie NJ, Reeves JT, et al. Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage. Am J Pathol. 2006;168(2):659–69. doi:10.2353/ajpath.2006.050599. Significant earlier paper demonstrating recruitment of circulating inflammatory cells to the vessel wall as determinant of remodeling in PH.
-
(2006)
Am J Pathol
, vol.168
, Issue.2
, pp. 659-669
-
-
Frid, M.G.1
Brunetti, J.A.2
Burke, D.L.3
Carpenter, T.C.4
Davie, N.J.5
Reeves, J.T.6
-
40
-
-
45849149991
-
Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection
-
PID: 18426996
-
Schnabel R, Larson MG, Dupuis J, Lunetta KL, Lipinska I, Meigs JB, et al. Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection. Hypertension. 2008;51(6):1651–7. doi:10.1161/HYPERTENSIONAHA.107.105668.
-
(2008)
Hypertension
, vol.51
, Issue.6
, pp. 1651-1657
-
-
Schnabel, R.1
Larson, M.G.2
Dupuis, J.3
Lunetta, K.L.4
Lipinska, I.5
Meigs, J.B.6
-
41
-
-
84869449419
-
Functional vascular smooth muscle cells derived from human induced pluripotent stem cells via mesenchymal stem cell intermediates
-
PID: 22941255
-
Bajpai VK, Mistriotis P, Loh YH, Daley GQ, Andreadis ST. Functional vascular smooth muscle cells derived from human induced pluripotent stem cells via mesenchymal stem cell intermediates. Cardiovasc Res. 2012;96(3):391–400. doi:10.1093/cvr/cvs253.
-
(2012)
Cardiovasc Res
, vol.96
, Issue.3
, pp. 391-400
-
-
Bajpai, V.K.1
Mistriotis, P.2
Loh, Y.H.3
Daley, G.Q.4
Andreadis, S.T.5
-
42
-
-
55049092713
-
In search of the in vivo identity of mesenchymal stem cells
-
PID: 18566331
-
da Silva Meirelles L, Caplan AI, Nardi NB. In search of the in vivo identity of mesenchymal stem cells. Stem Cells. 2008;26(9):2287–99. doi:10.1634/stemcells.2007-1122.
-
(2008)
Stem Cells
, vol.26
, Issue.9
, pp. 2287-2299
-
-
da Silva Meirelles, L.1
Caplan, A.I.2
Nardi, N.B.3
-
43
-
-
72149088455
-
Intrinsic extracellular matrix properties regulate stem cell differentiation
-
PID: 19800626
-
Reilly GC, Engler AJ. Intrinsic extracellular matrix properties regulate stem cell differentiation. J Biomech. 2010;43(1):55–62. doi:10.1016/j.jbiomech.2009.09.009.
-
(2010)
J Biomech
, vol.43
, Issue.1
, pp. 55-62
-
-
Reilly, G.C.1
Engler, A.J.2
-
44
-
-
77949568755
-
Effects of extracellular matrix on differentiation of human bone marrow-derived mesenchymal stem cells into smooth muscle cell lineage: utility for cardiovascular tissue engineering
-
PID: 19940434
-
Suzuki S, Narita Y, Yamawaki A, Murase Y, Satake M, Mutsuga M, et al. Effects of extracellular matrix on differentiation of human bone marrow-derived mesenchymal stem cells into smooth muscle cell lineage: utility for cardiovascular tissue engineering. Cells Tissues Organs. 2010;191(4):269–80. doi:10.1159/000260061.
-
(2010)
Cells Tissues Organs
, vol.191
, Issue.4
, pp. 269-280
-
-
Suzuki, S.1
Narita, Y.2
Yamawaki, A.3
Murase, Y.4
Satake, M.5
Mutsuga, M.6
-
45
-
-
33747152561
-
Matrix elasticity directs stem cell lineage specification
-
PID: 16923388
-
Engler AJ, Sen S, Sweeney HL, Discher DE. Matrix elasticity directs stem cell lineage specification. Cell. 2006;126(4):677–89. doi:10.1016/j.cell.2006.06.044.
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 677-689
-
-
Engler, A.J.1
Sen, S.2
Sweeney, H.L.3
Discher, D.E.4
-
46
-
-
27944497333
-
Tissue cells feel and respond to the stiffness of their substrate
-
PID: 16293750
-
Discher DE, Janmey P, Wang YL. Tissue cells feel and respond to the stiffness of their substrate. Science. 2005;310(5751):1139–43. doi:10.1126/science.1116995.
-
(2005)
Science
, vol.310
, Issue.5751
, pp. 1139-1143
-
-
Discher, D.E.1
Janmey, P.2
Wang, Y.L.3
-
47
-
-
77954608305
-
Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate
-
PID: 20418863
-
Huebsch N, Arany PR, Mao AS, Shvartsman D, Ali OA, Bencherif SA, et al. Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate. Nat Mater. 2010;9(6):518–26. doi:10.1038/nmat2732.
-
(2010)
Nat Mater
, vol.9
, Issue.6
, pp. 518-526
-
-
Huebsch, N.1
Arany, P.R.2
Mao, A.S.3
Shvartsman, D.4
Ali, O.A.5
Bencherif, S.A.6
-
48
-
-
84857791249
-
Compressive elasticity of three-dimensional nanofiber matrix directs mesenchymal stem cell differentiation to vascular cells with endothelial or smooth muscle cell markers
-
PID: 22266031
-
Wingate K, Bonani W, Tan Y, Bryant SJ, Tan W. Compressive elasticity of three-dimensional nanofiber matrix directs mesenchymal stem cell differentiation to vascular cells with endothelial or smooth muscle cell markers. Acta Biomater. 2012;8(4):1440–9. doi:10.1016/j.actbio.2011.12.032.
-
(2012)
Acta Biomater
, vol.8
, Issue.4
, pp. 1440-1449
-
-
Wingate, K.1
Bonani, W.2
Tan, Y.3
Bryant, S.J.4
Tan, W.5
-
49
-
-
84930175321
-
Three-dimensional, soft neotissue arrays as high throughput platforms for the interrogation of engineered tissue environments
-
PID: 25956850
-
Floren M, Tan W. Three-dimensional, soft neotissue arrays as high throughput platforms for the interrogation of engineered tissue environments. Biomaterials. 2015;59:39–52. doi:10.1016/j.biomaterials.2015.04.036.
-
(2015)
Biomaterials
, vol.59
, pp. 39-52
-
-
Floren, M.1
Tan, W.2
-
50
-
-
84883466306
-
A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors
-
PID: 23954413, Identifies YAP-TAZ as important mechanotrasduction pathway
-
Aragona M, Panciera T, Manfrin A, Giulitti S, Michielin F, Elvassore N, et al. A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors. Cell. 2013;154(5):1047–59. doi:10.1016/j.cell.2013.07.042. Identifies YAP-TAZ as important mechanotrasduction pathway.
-
(2013)
Cell
, vol.154
, Issue.5
, pp. 1047-1059
-
-
Aragona, M.1
Panciera, T.2
Manfrin, A.3
Giulitti, S.4
Michielin, F.5
Elvassore, N.6
-
51
-
-
84878615570
-
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
-
PID: 23708000, Demonstrates significance of YAP-TAZ signaling in cancer pathophysiology
-
Calvo F, Ege N, Grande-Garcia A, Hooper S, Jenkins RP, Chaudhry SI, et al. Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts. Nat Cell Biol. 2013;15(6):637–46. doi:10.1038/ncb2756. Demonstrates significance of YAP-TAZ signaling in cancer pathophysiology.
-
(2013)
Nat Cell Biol
, vol.15
, Issue.6
, pp. 637-646
-
-
Calvo, F.1
Ege, N.2
Grande-Garcia, A.3
Hooper, S.4
Jenkins, R.P.5
Chaudhry, S.I.6
-
52
-
-
84922967715
-
Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis
-
PID: 25502501
-
Liu F, Lagares D, Choi KM, Stopfer L, Marinkovic A, Vrbanac V, et al. Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis. Am J Physiol Lung Cell Mol Physiol. 2015;308(4):L344–57. doi:10.1152/ajplung.00300.2014.
-
(2015)
Am J Physiol Lung Cell Mol Physiol
, vol.308
, Issue.4
, pp. L344-L357
-
-
Liu, F.1
Lagares, D.2
Choi, K.M.3
Stopfer, L.4
Marinkovic, A.5
Vrbanac, V.6
-
53
-
-
79958284636
-
Role of YAP/TAZ in mechanotransduction
-
PID: 21654799
-
Dupont S, Morsut L, Aragona M, Enzo E, Giulitti S, Cordenonsi M, et al. Role of YAP/TAZ in mechanotransduction. Nature. 2011;474(7350):179–83. doi:10.1038/nature10137.
-
(2011)
Nature
, vol.474
, Issue.7350
, pp. 179-183
-
-
Dupont, S.1
Morsut, L.2
Aragona, M.3
Enzo, E.4
Giulitti, S.5
Cordenonsi, M.6
-
54
-
-
84865121019
-
Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction
-
PID: 22461426
-
Huang X, Yang N, Fiore VF, Barker TH, Sun Y, Morris SW, et al. Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction. Am J Respir Cell Mol Biol. 2012;47(3):340–8. doi:10.1165/rcmb.2012-0050OC.
-
(2012)
Am J Respir Cell Mol Biol
, vol.47
, Issue.3
, pp. 340-348
-
-
Huang, X.1
Yang, N.2
Fiore, V.F.3
Barker, T.H.4
Sun, Y.5
Morris, S.W.6
-
55
-
-
67349150059
-
High pulsatility flow induces adhesion molecule and cytokine mRNA expression in distal pulmonary artery endothelial cells
-
PID: 19340571
-
Li M, Scott DE, Shandas R, Stenmark KR, Tan W. High pulsatility flow induces adhesion molecule and cytokine mRNA expression in distal pulmonary artery endothelial cells. Ann Biomed Eng. 2009;37(6):1082–92. doi:10.1007/s10439-009-9684-3.
-
(2009)
Ann Biomed Eng
, vol.37
, Issue.6
, pp. 1082-1092
-
-
Li, M.1
Scott, D.E.2
Shandas, R.3
Stenmark, K.R.4
Tan, W.5
-
56
-
-
67649435681
-
Effects of pathological flow on pulmonary artery endothelial production of vasoactive mediators and growth factors
-
PID: 19571576
-
Li M, Stenmark KR, Shandas R, Tan W. Effects of pathological flow on pulmonary artery endothelial production of vasoactive mediators and growth factors. J Vasc Res. 2009;46(6):561–71. doi:10.1159/000226224.
-
(2009)
J Vasc Res
, vol.46
, Issue.6
, pp. 561-571
-
-
Li, M.1
Stenmark, K.R.2
Shandas, R.3
Tan, W.4
-
57
-
-
84874559005
-
High pulsatility flow induces acute endothelial inflammation through overpolarizing cells to activate NF-kappaB
-
PID: 23667401, Demonstrates linkage mechanism between disturbed flow and endothelial inflammatory response
-
Li M, Tan Y, Stenmark KR, Tan W. High pulsatility flow induces acute endothelial inflammation through overpolarizing cells to activate NF-kappaB. Cardiovasc Eng Technol. 2013;4(1):26–38. doi:10.1007/s13239-012-0115-5. Demonstrates linkage mechanism between disturbed flow and endothelial inflammatory response.
-
(2013)
Cardiovasc Eng Technol
, vol.4
, Issue.1
, pp. 26-38
-
-
Li, M.1
Tan, Y.2
Stenmark, K.R.3
Tan, W.4
-
58
-
-
84871886682
-
High pulsatility flow stimulates smooth muscle cell hypertrophy and contractile protein expression
-
PID: 23087017
-
Scott D, Tan Y, Shandas R, Stenmark KR, Tan W. High pulsatility flow stimulates smooth muscle cell hypertrophy and contractile protein expression. Am J Physiol Lung Cell Mol Physiol. 2013;304(1):L70–81. doi:10.1152/ajplung.00342.2012.
-
(2013)
Am J Physiol Lung Cell Mol Physiol
, vol.304
, Issue.1
, pp. L70-L81
-
-
Scott, D.1
Tan, Y.2
Shandas, R.3
Stenmark, K.R.4
Tan, W.5
-
59
-
-
84868475230
-
A new flow co-culture system for studying mechanobiology effects of pulse flow waves
-
PID: 22526489
-
Scott-Drechsel D, Su Z, Hunter K, Li M, Shandas R, Tan W. A new flow co-culture system for studying mechanobiology effects of pulse flow waves. Cytotechnology. 2012;64(6):649–66. doi:10.1007/s10616-012-9445-2.
-
(2012)
Cytotechnology
, vol.64
, Issue.6
, pp. 649-666
-
-
Scott-Drechsel, D.1
Su, Z.2
Hunter, K.3
Li, M.4
Shandas, R.5
Tan, W.6
-
60
-
-
84890067687
-
Influence of distal resistance and proximal stiffness on hemodynamics and RV afterload in progression and treatments of pulmonary hypertension: a computational study with validation using animal models
-
Su Z, Tan W, Shandas R, Hunter KS. Influence of distal resistance and proximal stiffness on hemodynamics and RV afterload in progression and treatments of pulmonary hypertension: a computational study with validation using animal models. Comp Math Methods Med. 2013;2013:618326. doi:10.1155/2013/618326.
-
(2013)
Comp Math Methods Med
, vol.2013
, pp. 618326
-
-
Su, Z.1
Tan, W.2
Shandas, R.3
Hunter, K.S.4
-
61
-
-
52449121945
-
Development and evaluation of microdevices for studying anisotropic biaxial cyclic stretch on cells
-
PID: 18563571
-
Tan W, Scott D, Belchenko D, Qi HJ, Xiao L. Development and evaluation of microdevices for studying anisotropic biaxial cyclic stretch on cells. Biomed Microdevices. 2008;10(6):869–82. doi:10.1007/s10544-008-9201-8.
-
(2008)
Biomed Microdevices
, vol.10
, Issue.6
, pp. 869-882
-
-
Tan, W.1
Scott, D.2
Belchenko, D.3
Qi, H.J.4
Xiao, L.5
-
62
-
-
84904350882
-
Stiffening-induced high pulsatility flow activates endothelial inflammation via a TLR2/NF-kappaB pathway
-
PID: 25029271
-
Tan Y, Tseng PO, Wang D, Zhang H, Hunter K, Hertzberg J, et al. Stiffening-induced high pulsatility flow activates endothelial inflammation via a TLR2/NF-kappaB pathway. PLoS One. 2014;9(7):e102195. doi:10.1371/journal.pone.0102195.
-
(2014)
PLoS One
, vol.9
, Issue.7
, pp. e102195
-
-
Tan, Y.1
Tseng, P.O.2
Wang, D.3
Zhang, H.4
Hunter, K.5
Hertzberg, J.6
-
63
-
-
70350446656
-
Importance of pulsatility in hypertensive carotid artery growth and remodeling
-
PID: 19584753
-
Eberth JF, Gresham VC, Reddy AK, Popovic N, Wilson E, Humphrey JD. Importance of pulsatility in hypertensive carotid artery growth and remodeling. J Hypertens. 2009;27(10):2010–21. doi:10.1097/HJH.0b013e32832e8dc8.
-
(2009)
J Hypertens
, vol.27
, Issue.10
, pp. 2010-2021
-
-
Eberth, J.F.1
Gresham, V.C.2
Reddy, A.K.3
Popovic, N.4
Wilson, E.5
Humphrey, J.D.6
-
64
-
-
78649753172
-
Time course of carotid artery growth and remodeling in response to altered pulsatility
-
PID: 20852047
-
Eberth JF, Popovic N, Gresham VC, Wilson E, Humphrey JD. Time course of carotid artery growth and remodeling in response to altered pulsatility. Am J Physiol Heart Circ Physiol. 2010;299(6):H1875–83. doi:10.1152/ajpheart.00872.2009.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.299
, Issue.6
, pp. H1875-H1883
-
-
Eberth, J.F.1
Popovic, N.2
Gresham, V.C.3
Wilson, E.4
Humphrey, J.D.5
-
65
-
-
5344233478
-
Pulmonary arterial hypertension
-
PID: 15483284
-
Farber HW, Loscalzo J. Pulmonary arterial hypertension. N Engl J Med. 2004;351(16):1655–65. doi:10.1056/NEJMra035488.
-
(2004)
N Engl J Med
, vol.351
, Issue.16
, pp. 1655-1665
-
-
Farber, H.W.1
Loscalzo, J.2
-
66
-
-
84886437293
-
Pulmonary arterial hypertension: challenges in translational research and a vision for change
-
PID: 24154604
-
Sutendra G, Michelakis ED. Pulmonary arterial hypertension: challenges in translational research and a vision for change. Sci Transl Med. 2013;5(208):208sr5. doi:10.1126/scitranslmed.3005428.
-
(2013)
Sci Transl Med
, vol.5
, Issue.208
, pp. 208sr5
-
-
Sutendra, G.1
Michelakis, E.D.2
-
67
-
-
84890606655
-
Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology
-
PID: 24355638, Vonk-Noordegraaf’s review outlines the pathophysiology and changes in RV morphology throughout the course of PAH. This focused comprehensive review provides great clinical comparative examples to LV failure, and introduces both mechanical and molecular basis of RV remodeling as well introduces the most recent translational studies
-
Vonk-Noordegraaf A, Haddad F, Chin KM, Forfia PR, Kawut SM, Lumens J, et al. Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology. J Am Coll Cardiol. 2013;62(25 Suppl):D22–33. doi:10.1016/j.jacc.2013.10.027. Vonk-Noordegraaf’s review outlines the pathophysiology and changes in RV morphology throughout the course of PAH. This focused comprehensive review provides great clinical comparative examples to LV failure, and introduces both mechanical and molecular basis of RV remodeling as well introduces the most recent translational studies.
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. D22-D33
-
-
Vonk-Noordegraaf, A.1
Haddad, F.2
Chin, K.M.3
Forfia, P.R.4
Kawut, S.M.5
Lumens, J.6
-
68
-
-
78449300043
-
The arterial load in pulmonary hypertension
-
PID: 20956192
-
Saouti N, Westerhof N, Postmus PE, Vonk-Noordegraaf A. The arterial load in pulmonary hypertension. Eur Respir Rev. 2010;19(117):197–203. doi:10.1183/09059180.00002210.
-
(2010)
Eur Respir Rev
, vol.19
, Issue.117
, pp. 197-203
-
-
Saouti, N.1
Westerhof, N.2
Postmus, P.E.3
Vonk-Noordegraaf, A.4
-
69
-
-
84655163391
-
Right ventriculo-arterial coupling in pulmonary hypertension: a magnetic resonance study
-
PID: 21917658
-
Sanz J, Garcia-Alvarez A, Fernandez-Friera L, Nair A, Mirelis JG, Sawit ST, et al. Right ventriculo-arterial coupling in pulmonary hypertension: a magnetic resonance study. Heart. 2012;98(3):238–43. doi:10.1136/heartjnl-2011-300462.
-
(2012)
Heart
, vol.98
, Issue.3
, pp. 238-243
-
-
Sanz, J.1
Garcia-Alvarez, A.2
Fernandez-Friera, L.3
Nair, A.4
Mirelis, J.G.5
Sawit, S.T.6
-
70
-
-
84929430687
-
Noninvasive imaging in the assessment of the cardiopulmonary vascular unit
-
PID: 25753343
-
Vonk Noordegraaf A, Haddad F, Bogaard HJ, Hassoun PM. Noninvasive imaging in the assessment of the cardiopulmonary vascular unit. Circulation. 2015;131(10):899–913. doi:10.1161/CIRCULATIONAHA.114.006972.
-
(2015)
Circulation
, vol.131
, Issue.10
, pp. 899-913
-
-
Vonk Noordegraaf, A.1
Haddad, F.2
Bogaard, H.J.3
Hassoun, P.M.4
-
71
-
-
65549110809
-
Right atrial volume index in chronic systolic heart failure and prognosis
-
PID: 19442936
-
Sallach JA, Tang WH, Borowski AG, Tong W, Porter T, Martin MG, et al. Right atrial volume index in chronic systolic heart failure and prognosis. JACC Cardiovasc Imaging. 2009;2(5):527–34. doi:10.1016/j.jcmg.2009.01.012.
-
(2009)
JACC Cardiovasc Imaging
, vol.2
, Issue.5
, pp. 527-534
-
-
Sallach, J.A.1
Tang, W.H.2
Borowski, A.G.3
Tong, W.4
Porter, T.5
Martin, M.G.6
-
72
-
-
84925296451
-
Right ventricular remodeling in idiopathic pulmonary arterial hypertension: adaptive versus maladaptive morphology
-
PID: 25499139
-
Badagliacca R, Poscia R, Pezzuto B, Nocioni M, Mezzapesa M, Francone M, et al. Right ventricular remodeling in idiopathic pulmonary arterial hypertension: adaptive versus maladaptive morphology. J Heart Lung Transplant. 2015;34(3):395–403. doi:10.1016/j.healun.2014.11.002.
-
(2015)
J Heart Lung Transplant
, vol.34
, Issue.3
, pp. 395-403
-
-
Badagliacca, R.1
Poscia, R.2
Pezzuto, B.3
Nocioni, M.4
Mezzapesa, M.5
Francone, M.6
-
73
-
-
84930740448
-
Right heart score for predicting outcome in idiopathic, familial, or drug- and toxin-associated pulmonary arterial hypertension
-
PID: 25981508, After NIH and REVEAL studies, this is next major clinical research article proposing the newest predictive model based on the RV functionality. Authors used multi-modal imaging and standard clinical indices to assess the multivariate model offering reader to get familiar with the most up-to-date clinical PAH and RV function modalities
-
Haddad F, Spruijt OA, Denault AY, Mercier O, Brunner N, Furman D, et al. Right heart score for predicting outcome in idiopathic, familial, or drug- and toxin-associated pulmonary arterial hypertension. JACC Cardiovasc Imaging. 2015;8(6):627–38. doi:10.1016/j.jcmg.2014.12.029. After NIH and REVEAL studies, this is next major clinical research article proposing the newest predictive model based on the RV functionality. Authors used multi-modal imaging and standard clinical indices to assess the multivariate model offering reader to get familiar with the most up-to-date clinical PAH and RV function modalities.
-
(2015)
JACC Cardiovasc Imaging
, vol.8
, Issue.6
, pp. 627-638
-
-
Haddad, F.1
Spruijt, O.A.2
Denault, A.Y.3
Mercier, O.4
Brunner, N.5
Furman, D.6
-
74
-
-
84863011141
-
The REVEAL Registry risk score calculator in patients newly diagnosed with pulmonary arterial hypertension
-
PID: 21680644, Benchmark study on the REVEAL registry risk score calculator
-
Benza RL, Gomberg-Maitland M, Miller DP, Frost A, Frantz RP, Foreman AJ, et al. The REVEAL Registry risk score calculator in patients newly diagnosed with pulmonary arterial hypertension. Chest. 2012;141(2):354–62. doi:10.1378/chest.11-0676. Benchmark study on the REVEAL registry risk score calculator.
-
(2012)
Chest
, vol.141
, Issue.2
, pp. 354-362
-
-
Benza, R.L.1
Gomberg-Maitland, M.2
Miller, D.P.3
Frost, A.4
Frantz, R.P.5
Foreman, A.J.6
-
75
-
-
70349776690
-
Comprehensive invasive and noninvasive approach to the right ventricle-pulmonary circulation unit: state of the art and clinical and research implications
-
PID: 19752350
-
Champion HC, Michelakis ED, Hassoun PM. Comprehensive invasive and noninvasive approach to the right ventricle-pulmonary circulation unit: state of the art and clinical and research implications. Circulation. 2009;120(11):992–1007. doi:10.1161/CIRCULATIONAHA.106.674028.
-
(2009)
Circulation
, vol.120
, Issue.11
, pp. 992-1007
-
-
Champion, H.C.1
Michelakis, E.D.2
Hassoun, P.M.3
-
76
-
-
70049112901
-
Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)
-
PID: 19713419
-
Galie N, Hoeper MM, Humbert M, Torbicki A, Vachiery JL, Barbera JA, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J. 2009;30(20):2493–537. doi:10.1093/eurheartj/ehp297.
-
(2009)
Eur Heart J
, vol.30
, Issue.20
, pp. 2493-2537
-
-
Galie, N.1
Hoeper, M.M.2
Humbert, M.3
Torbicki, A.4
Vachiery, J.L.5
Barbera, J.A.6
-
77
-
-
84886085645
-
Noninvasive estimation of PA pressure, flow, and resistance with CMR imaging: derivation and prospective validation study from the ASPIRE registry
-
PID: 23769494
-
Swift AJ, Rajaram S, Hurdman J, Hill C, Davies C, Sproson TW, et al. Noninvasive estimation of PA pressure, flow, and resistance with CMR imaging: derivation and prospective validation study from the ASPIRE registry. JACC Cardiovasc Imaging. 2013;6(10):1036–47. doi:10.1016/j.jcmg.2013.01.013.
-
(2013)
JACC Cardiovasc Imaging
, vol.6
, Issue.10
, pp. 1036-1047
-
-
Swift, A.J.1
Rajaram, S.2
Hurdman, J.3
Hill, C.4
Davies, C.5
Sproson, T.W.6
-
78
-
-
46849106936
-
Pulmonary vascular resistance and compliance stay inversely related during treatment of pulmonary hypertension
-
PID: 18349027
-
Lankhaar JW, Westerhof N, Faes TJ, Gan CT, Marques KM, Boonstra A, et al. Pulmonary vascular resistance and compliance stay inversely related during treatment of pulmonary hypertension. Eur Heart J. 2008;29(13):1688–95. doi:10.1093/eurheartj/ehn103.
-
(2008)
Eur Heart J
, vol.29
, Issue.13
, pp. 1688-1695
-
-
Lankhaar, J.W.1
Westerhof, N.2
Faes, T.J.3
Gan, C.T.4
Marques, K.M.5
Boonstra, A.6
-
79
-
-
67649613565
-
Diagnosis, assessment, and treatment of non-pulmonary arterial hypertension pulmonary hypertension
-
PID: 19555862
-
Hoeper MM, Barbera JA, Channick RN, Hassoun PM, Lang IM, Manes A, et al. Diagnosis, assessment, and treatment of non-pulmonary arterial hypertension pulmonary hypertension. J Am Coll Cardiol. 2009;54(1 Suppl):S85–96. doi:10.1016/j.jacc.2009.04.008.
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. S85-S96
-
-
Hoeper, M.M.1
Barbera, J.A.2
Channick, R.N.3
Hassoun, P.M.4
Lang, I.M.5
Manes, A.6
-
80
-
-
33750560212
-
Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure
-
PID: 17060398
-
Voelkel NF, Quaife RA, Leinwand LA, Barst RJ, McGoon MD, Meldrum DR, et al. Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure. Circulation. 2006;114(17):1883–91. doi:10.1161/CIRCULATIONAHA.106.632208.
-
(2006)
Circulation
, vol.114
, Issue.17
, pp. 1883-1891
-
-
Voelkel, N.F.1
Quaife, R.A.2
Leinwand, L.A.3
Barst, R.J.4
McGoon, M.D.5
Meldrum, D.R.6
-
81
-
-
84937685599
-
-
Wells JM, Iyer AS, Rahaghi FN, Bhatt SP, Gupta H, Denney TS et al. Pulmonary artery enlargement is associated with right ventricular dysfunction and loss of blood volume in small pulmonary vessels in chronic obstructive pulmonary disease. Circ Cardiovasc Imaging. 2015;8(4).
-
Wells JM, Iyer AS, Rahaghi FN, Bhatt SP, Gupta H, Denney TS et al. Pulmonary artery enlargement is associated with right ventricular dysfunction and loss of blood volume in small pulmonary vessels in chronic obstructive pulmonary disease. Circ Cardiovasc Imaging. 2015;8(4). doi:10.1161/CIRCIMAGING.114.002546.
-
-
-
-
82
-
-
66549127501
-
ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association
-
PID: 19332472
-
McLaughlin VV, Archer SL, Badesch DB, Barst RJ, Farber HW, Lindner JR, et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association. Circulation. 2009;119(16):2250–94. doi:10.1161/CIRCULATIONAHA.109.192230.
-
(2009)
Circulation
, vol.119
, Issue.16
, pp. 2250-2294
-
-
McLaughlin, V.V.1
Archer, S.L.2
Badesch, D.B.3
Barst, R.J.4
Farber, H.W.5
Lindner, J.R.6
-
83
-
-
74949141587
-
Ventricular geometry, strain, and rotational mechanics in pulmonary hypertension
-
PID: 20048214
-
Puwanant S, Park M, Popovic ZB, Tang WH, Farha S, George D, et al. Ventricular geometry, strain, and rotational mechanics in pulmonary hypertension. Circulation. 2010;121(2):259–66. doi:10.1161/CIRCULATIONAHA.108.844340.
-
(2010)
Circulation
, vol.121
, Issue.2
, pp. 259-266
-
-
Puwanant, S.1
Park, M.2
Popovic, Z.B.3
Tang, W.H.4
Farha, S.5
George, D.6
-
84
-
-
84930696045
-
Right intraventricular dyssynchrony in idiopathic, heritable, and anorexigen-induced pulmonary arterial hypertension: clinical impact and reversibility
-
PID: 25981504, Clinically oriented research article by Badagliacca focusing on the RV performance in the setting of PAH. Relatively novel mechanical term of dyssynchrony is adapted to assess the RV prognostic role using non-invasive echocardiographic speckle tissue tracking technique
-
Badagliacca R, Reali M, Poscia R, Pezzuto B, Papa S, Mezzapesa M, et al. Right intraventricular dyssynchrony in idiopathic, heritable, and anorexigen-induced pulmonary arterial hypertension: clinical impact and reversibility. JACC Cardiovasc Imaging. 2015;8(6):642–52. doi:10.1016/j.jcmg.2015.02.009. Clinically oriented research article by Badagliacca focusing on the RV performance in the setting of PAH. Relatively novel mechanical term of dyssynchrony is adapted to assess the RV prognostic role using non-invasive echocardiographic speckle tissue tracking technique.
-
(2015)
JACC Cardiovasc Imaging
, vol.8
, Issue.6
, pp. 642-652
-
-
Badagliacca, R.1
Reali, M.2
Poscia, R.3
Pezzuto, B.4
Papa, S.5
Mezzapesa, M.6
-
85
-
-
74949119469
-
Reduced ascending aortic strain and distensibility: earliest manifestations of vascular aging in humans
-
PID: 20065154
-
Redheuil A, Yu WC, Wu CO, Mousseaux E, de Cesare A, Yan R, et al. Reduced ascending aortic strain and distensibility: earliest manifestations of vascular aging in humans. Hypertension. 2010;55(2):319–26. doi:10.1161/HYPERTENSIONAHA.109.141275.
-
(2010)
Hypertension
, vol.55
, Issue.2
, pp. 319-326
-
-
Redheuil, A.1
Yu, W.C.2
Wu, C.O.3
Mousseaux, E.4
de Cesare, A.5
Yan, R.6
-
86
-
-
84878154632
-
Pulmonary artery pulse wave velocity in idiopathic pulmonary arterial hypertension
-
PID: 23260799
-
Kopec G, Moertl D, Jankowski P, Tyrka A, Sobien B, Podolec P. Pulmonary artery pulse wave velocity in idiopathic pulmonary arterial hypertension. Can J Cardiol. 2013;29(6):683–90. doi:10.1016/j.cjca.2012.09.019.
-
(2013)
Can J Cardiol
, vol.29
, Issue.6
, pp. 683-690
-
-
Kopec, G.1
Moertl, D.2
Jankowski, P.3
Tyrka, A.4
Sobien, B.5
Podolec, P.6
-
87
-
-
84876510984
-
Pulmonary hypertension secondary to COPD
-
PID: 22973510
-
Shujaat A, Bajwa AA, Cury JD. Pulmonary hypertension secondary to COPD. Pulm Med. 2012;2012:203952. doi:10.1155/2012/203952.
-
(2012)
Pulm Med
, vol.2012
, pp. 203952
-
-
Shujaat, A.1
Bajwa, A.A.2
Cury, J.D.3
-
88
-
-
32644435423
-
Relationship of pulmonary arterial capacitance and mortality in idiopathic pulmonary arterial hypertension
-
PID: 16487848, Foundational study demonstrating vascular stiffening as a prognostic marker in PH
-
Mahapatra S, Nishimura RA, Sorajja P, Cha S, McGoon MD. Relationship of pulmonary arterial capacitance and mortality in idiopathic pulmonary arterial hypertension. J Am Coll Cardiol. 2006;47(4):799–803. doi:10.1016/j.jacc.2005.09.054. Foundational study demonstrating vascular stiffening as a prognostic marker in PH.
-
(2006)
J Am Coll Cardiol
, vol.47
, Issue.4
, pp. 799-803
-
-
Mahapatra, S.1
Nishimura, R.A.2
Sorajja, P.3
Cha, S.4
McGoon, M.D.5
-
89
-
-
84928062539
-
Four-dimensional flow assessment of pulmonary artery flow and wall shear stress in adult pulmonary arterial hypertension: results from two institutions
-
PID: 24974951
-
Barker AJ, Roldan-Alzate A, Entezari P, Shah SJ, Chesler NC, Wieben O, et al. Four-dimensional flow assessment of pulmonary artery flow and wall shear stress in adult pulmonary arterial hypertension: results from two institutions. Magn Reson Med. 2015;73(5):1904–13. doi:10.1002/mrm.25326.
-
(2015)
Magn Reson Med
, vol.73
, Issue.5
, pp. 1904-1913
-
-
Barker, A.J.1
Roldan-Alzate, A.2
Entezari, P.3
Shah, S.J.4
Chesler, N.C.5
Wieben, O.6
-
90
-
-
84938877250
-
4D flow cardiovascular magnetic resonance consensus statement
-
PID: 26257141
-
Dyverfeldt P, Bissell M, Barker AJ, Bolger AF, Carlhall CJ, Ebbers T, et al. 4D flow cardiovascular magnetic resonance consensus statement. J Cardiovasc Magn Reson. 2015;17(1):72. doi:10.1186/s12968-015-0174-5.
-
(2015)
J Cardiovasc Magn Reson
, vol.17
, Issue.1
, pp. 72
-
-
Dyverfeldt, P.1
Bissell, M.2
Barker, A.J.3
Bolger, A.F.4
Carlhall, C.J.5
Ebbers, T.6
-
91
-
-
84885928303
-
Intracardiac flow visualization: current status and future directions
-
PID: 23907342, This imaging focuses review, introduces concept of qualitative and quantitative flow markers obtained by state-of-the-art echocardiographic and MRI techniques. It is focused on both vascular and intracardiac pattern in systemic and pulmonary circuits
-
Rodriguez Munoz D, Markl M, Moya Mur JL, Barker A, Fernandez-Golfin C, Lancellotti P, et al. Intracardiac flow visualization: current status and future directions. Eur Heart J Cardiovasc Imaging. 2013;14(11):1029–38. doi:10.1093/ehjci/jet086. This imaging focuses review, introduces concept of qualitative and quantitative flow markers obtained by state-of-the-art echocardiographic and MRI techniques. It is focused on both vascular and intracardiac pattern in systemic and pulmonary circuits.
-
(2013)
Eur Heart J Cardiovasc Imaging
, vol.14
, Issue.11
, pp. 1029-1038
-
-
Rodriguez Munoz, D.1
Markl, M.2
Moya Mur, J.L.3
Barker, A.4
Fernandez-Golfin, C.5
Lancellotti, P.6
-
92
-
-
84856092224
-
Pulmonary capillary wedge pressure augments right ventricular pulsatile loading
-
PID: 22131357
-
Tedford RJ, Hassoun PM, Mathai SC, Girgis RE, Russell SD, Thiemann DR, et al. Pulmonary capillary wedge pressure augments right ventricular pulsatile loading. Circulation. 2012;125(2):289–97. doi:10.1161/CIRCULATIONAHA.111.051540.
-
(2012)
Circulation
, vol.125
, Issue.2
, pp. 289-297
-
-
Tedford, R.J.1
Hassoun, P.M.2
Mathai, S.C.3
Girgis, R.E.4
Russell, S.D.5
Thiemann, D.R.6
-
93
-
-
84911934131
-
Review of MRI-based measurements of pulse wave velocity: a biomarker of arterial stiffness
-
PID: 24834415
-
Wentland AL, Grist TM, Wieben O. Review of MRI-based measurements of pulse wave velocity: a biomarker of arterial stiffness. Cardiovasc Diagn Ther. 2014;4(2):193–206. doi:10.3978/j.issn.2223-3652.2014.03.04.
-
(2014)
Cardiovasc Diagn Ther
, vol.4
, Issue.2
, pp. 193-206
-
-
Wentland, A.L.1
Grist, T.M.2
Wieben, O.3
-
94
-
-
84872682819
-
Assessment of normal flow patterns in the pulmonary circulation by using 4D magnetic resonance velocity mapping
-
PID: 22898700
-
Bachler P, Pinochet N, Sotelo J, Crelier G, Irarrazaval P, Tejos C, et al. Assessment of normal flow patterns in the pulmonary circulation by using 4D magnetic resonance velocity mapping. Magn Reson Imaging. 2013;31(2):178–88. doi:10.1016/j.mri.2012.06.036.
-
(2013)
Magn Reson Imaging
, vol.31
, Issue.2
, pp. 178-188
-
-
Bachler, P.1
Pinochet, N.2
Sotelo, J.3
Crelier, G.4
Irarrazaval, P.5
Tejos, C.6
-
95
-
-
67649186010
-
Magnetic resonance-derived 3-dimensional blood flow patterns in the main pulmonary artery as a marker of pulmonary hypertension and a measure of elevated mean pulmonary arterial pressure
-
PID: 19808511
-
Reiter G, Reiter U, Kovacs G, Kainz B, Schmidt K, Maier R, et al. Magnetic resonance-derived 3-dimensional blood flow patterns in the main pulmonary artery as a marker of pulmonary hypertension and a measure of elevated mean pulmonary arterial pressure. Circ Cardiovasc Imaging. 2008;1(1):23–30. doi:10.1161/CIRCIMAGING.108.780247.
-
(2008)
Circ Cardiovasc Imaging
, vol.1
, Issue.1
, pp. 23-30
-
-
Reiter, G.1
Reiter, U.2
Kovacs, G.3
Kainz, B.4
Schmidt, K.5
Maier, R.6
-
96
-
-
84878235301
-
Venous and arterial flow quantification are equally accurate and precise with parallel imaging compressed sensing 4D phase contrast MRI
-
PID: 23172846
-
Tariq U, Hsiao A, Alley M, Zhang T, Lustig M, Vasanawala SS. Venous and arterial flow quantification are equally accurate and precise with parallel imaging compressed sensing 4D phase contrast MRI. J Magn Reson Imaging. 2013;37(6):1419–26. doi:10.1002/jmri.23936.
-
(2013)
J Magn Reson Imaging
, vol.37
, Issue.6
, pp. 1419-1426
-
-
Tariq, U.1
Hsiao, A.2
Alley, M.3
Zhang, T.4
Lustig, M.5
Vasanawala, S.S.6
-
97
-
-
84892617751
-
Evaluation of elevated mean pulmonary arterial pressure based on magnetic resonance 4D velocity mapping: comparison of visualization techniques
-
PID: 24349224
-
Reiter U, Reiter G, Kovacs G, Stalder AF, Gulsun MA, Greiser A, et al. Evaluation of elevated mean pulmonary arterial pressure based on magnetic resonance 4D velocity mapping: comparison of visualization techniques. PLoS One. 2013;8(12):e82212. doi:10.1371/journal.pone.0082212.
-
(2013)
PLoS One
, vol.8
, Issue.12
, pp. e82212
-
-
Reiter, U.1
Reiter, G.2
Kovacs, G.3
Stalder, A.F.4
Gulsun, M.A.5
Greiser, A.6
-
98
-
-
84941670630
-
Vorticity is a marker of right ventricular diastolic dysfunction
-
PID: 26254331
-
Fenster BE, Browning J, Schroeder JD, Schafer M, Podgorski CA, Smyser J, et al. Vorticity is a marker of right ventricular diastolic dysfunction. Am J Physiol Heart Circ Physiol. 2015;309(6):H1087–93. doi:10.1152/ajpheart.00278.2015.
-
(2015)
Am J Physiol Heart Circ Physiol
, vol.309
, Issue.6
, pp. H1087-H1093
-
-
Fenster, B.E.1
Browning, J.2
Schroeder, J.D.3
Schafer, M.4
Podgorski, C.A.5
Smyser, J.6
-
99
-
-
84884362647
-
Ventricular-arterial coupling, remodeling, and prognosis in chronic heart failure
-
PID: 23770174
-
Ky B, French B, May Khan A, Plappert T, Wang A, Chirinos JA, et al. Ventricular-arterial coupling, remodeling, and prognosis in chronic heart failure. J Am Coll Cardiol. 2013;62(13):1165–72. doi:10.1016/j.jacc.2013.03.085.
-
(2013)
J Am Coll Cardiol
, vol.62
, Issue.13
, pp. 1165-1172
-
-
Ky, B.1
French, B.2
May Khan, A.3
Plappert, T.4
Wang, A.5
Chirinos, J.A.6
-
100
-
-
0020858768
-
Left ventricular interaction with arterial load studied in isolated canine ventricle
-
PID: 6638199
-
Sunagawa K, Maughan WL, Burkhoff D, Sagawa K. Left ventricular interaction with arterial load studied in isolated canine ventricle. Am J Physiol. 1983;245(5 Pt 1):H773–80.
-
(1983)
Am J Physiol
, vol.245
, pp. H773-H780
-
-
Sunagawa, K.1
Maughan, W.L.2
Burkhoff, D.3
Sagawa, K.4
-
101
-
-
55449097293
-
Arterial-ventricular coupling: mechanistic insights into cardiovascular performance at rest and during exercise
-
Chantler PD, Lakatta EG, Najjar SS. Arterial-ventricular coupling: mechanistic insights into cardiovascular performance at rest and during exercise. J Appl Physiol (1985). 2008;105(4):1342–51. doi:10.1152/japplphysiol.90600.2008.
-
(2008)
J Appl Physiol (1985)
, vol.105
, Issue.4
, pp. 1342-1351
-
-
Chantler, P.D.1
Lakatta, E.G.2
Najjar, S.S.3
-
102
-
-
84890585231
-
Non-invasive indices of right ventricular function are markers of ventricular-arterial coupling rather than ventricular contractility: insights from a porcine model of chronic pressure overload
-
PID: 23677917, This translational research oriented manuscript provides comprehensive evidence of the crucial role of the RV in PAH prognosis, and function of the RV-PA axis. Authors investigate in greatly designed study the ventriculo-vascular coupling and compare standard predicting hemodynamic markers
-
Guihaire J, Haddad F, Boulate D, Decante B, Denault AY, Wu J, et al. Non-invasive indices of right ventricular function are markers of ventricular-arterial coupling rather than ventricular contractility: insights from a porcine model of chronic pressure overload. Eur Heart J Cardiovasc Imaging. 2013;14(12):1140–9. doi:10.1093/ehjci/jet092. This translational research oriented manuscript provides comprehensive evidence of the crucial role of the RV in PAH prognosis, and function of the RV-PA axis. Authors investigate in greatly designed study the ventriculo-vascular coupling and compare standard predicting hemodynamic markers.
-
(2013)
Eur Heart J Cardiovasc Imaging
, vol.14
, Issue.12
, pp. 1140-1149
-
-
Guihaire, J.1
Haddad, F.2
Boulate, D.3
Decante, B.4
Denault, A.Y.5
Wu, J.6
-
103
-
-
84919725040
-
RV-pulmonary arterial coupling predicts outcome in patients referred for pulmonary hypertension
-
PID: 25214501, Clinical study focusing on the RV-arterial coupling signifying the work done by Guihaire et al. (2013). Authors apply basic 2D CMR volumetric imaging in large cohort of patients to investigate the VVCR and further analyzed the prognostic potential. This study is one of the premiere investigations in the clinical setting evaluating considerable amount of patients on RV-PA axis basis
-
Vanderpool RR, Pinsky MR, Naeije R, Deible C, Kosaraju V, Bunner C, et al. RV-pulmonary arterial coupling predicts outcome in patients referred for pulmonary hypertension. Heart. 2015;101(1):37–43. doi:10.1136/heartjnl-2014-306142. Clinical study focusing on the RV-arterial coupling signifying the work done by Guihaire et al. (2013). Authors apply basic 2D CMR volumetric imaging in large cohort of patients to investigate the VVCR and further analyzed the prognostic potential. This study is one of the premiere investigations in the clinical setting evaluating considerable amount of patients on RV-PA axis basis.
-
(2015)
Heart
, vol.101
, Issue.1
, pp. 37-43
-
-
Vanderpool, R.R.1
Pinsky, M.R.2
Naeije, R.3
Deible, C.4
Kosaraju, V.5
Bunner, C.6
|