-
2
-
-
0034702282
-
Causes and outcomes of the acute chest syndrome in sickle cell disease
-
Vichinsky EP, Neumayr LD, Earles AN, et al. Causes and outcomes of the acute chest syndrome in sickle cell disease. N Engl J Med 2000;342:1855–1865.
-
(2000)
N Engl J Med
, vol.342
, pp. 1855-1865
-
-
Vichinsky, E.P.1
Neumayr, L.D.2
Earles, A.N.3
-
3
-
-
0036019803
-
Sickle cell nephropathy at end-stage renal disease in the United States: Patient characteristics and survival
-
Abbott KC, Hypolite IO, Agodoa LY. Sickle cell nephropathy at end-stage renal disease in the United States: patient characteristics and survival. Clin Nephrol 2002;58:9–15.
-
(2002)
Clin Nephrol
, vol.58
, pp. 9-15
-
-
Abbott, K.C.1
Hypolite, I.O.2
Agodoa, L.Y.3
-
5
-
-
33750623537
-
Treatment and prevention of stroke in children with sickle cell disease
-
Mehta SH, Adams RJ. Treatment and prevention of stroke in children with sickle cell disease. Curr Treat Options Neurol 2006;8:503–512.
-
(2006)
Curr Treat Options Neurol
, vol.8
, pp. 503-512
-
-
Mehta, S.H.1
Adams, R.J.2
-
6
-
-
34547394899
-
Sickle cell lung disease and sudden death: A retrospective/ prospective study of 21 autopsy cases and literature review
-
Graham JK, Mosunjac M, Hanzlick RL, Mosunjac M. Sickle cell lung disease and sudden death: a retrospective/ prospective study of 21 autopsy cases and literature review. Am J Forensic Med Pathol 2007;28:168–172.
-
(2007)
Am J Forensic Med Pathol
, vol.28
, pp. 168-172
-
-
Graham, J.K.1
Mosunjac, M.2
Hanzlick, R.L.3
Mosunjac, M.4
-
7
-
-
0036802402
-
Pulmonary hypertension in sickle cell hemoglobinopathy: A clinicopathologic study of 20 cases
-
Haque AK, Gokhale S, Rampy BA, Adegboyega P, Duarte A, Saldana MJ. Pulmonary hypertension in sickle cell hemoglobinopathy: a clinicopathologic study of 20 cases. Hum Pathol 2002;33:1037–1043.
-
(2002)
Hum Pathol
, vol.33
, pp. 1037-1043
-
-
Haque, A.K.1
Gokhale, S.2
Rampy, B.A.3
Adegboyega, P.4
Duarte, A.5
Saldana, M.J.6
-
8
-
-
81255174878
-
Pulmonary hypertension diagnosed by right heart catheterisation in sickle cell disease
-
Fonseca GH, Souza R, Salemi VM, Jardim CV, Gualandro SF. Pulmonary hypertension diagnosed by right heart catheterisation in sickle cell disease. Eur Respir J 2012;39:112–118.
-
(2012)
Eur Respir J
, vol.39
, pp. 112-118
-
-
Fonseca, G.H.1
Souza, R.2
Salemi, V.M.3
Jardim, C.V.4
Gualandro, S.F.5
-
9
-
-
84876857053
-
Hemodynamic predictors of mortality in adults with sickle cell disease
-
Mehari A, Alam S, Tian X, et al. Hemodynamic predictors of mortality in adults with sickle cell disease. Am J Respir Crit Care Med 2013;187:840–847.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 840-847
-
-
Mehari, A.1
Alam, S.2
Tian, X.3
-
10
-
-
84859173084
-
Mortality in adults with sickle cell disease and pulmonary hypertension
-
Mehari A, Gladwin MT, Tian X, Machado RF, Kato GJ. Mortality in adults with sickle cell disease and pulmonary hypertension. JAMA 2012;307:1254–1256.
-
(2012)
JAMA
, vol.307
, pp. 1254-1256
-
-
Mehari, A.1
Gladwin, M.T.2
Tian, X.3
Machado, R.F.4
Kato, G.J.5
-
11
-
-
79960101398
-
A hemodynamic study of pulmonary hypertension in sickle cell disease
-
Parent F, Bachir D, Inamo J, et al. A hemodynamic study of pulmonary hypertension in sickle cell disease. N Engl J Med 2011;365:44–53.
-
(2011)
N Engl J Med
, vol.365
, pp. 44-53
-
-
Parent, F.1
Bachir, D.2
Inamo, J.3
-
12
-
-
10744233940
-
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease
-
Gladwin MT, Sachdev V, Jison ML, et al. Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. N Engl J Med 2004;350:886–895.
-
(2004)
N Engl J Med
, vol.350
, pp. 886-895
-
-
Gladwin, M.T.1
Sachdev, V.2
Jison, M.L.3
-
13
-
-
33744810662
-
Pulmonary hypertension in patients with sickle cell disease: A longitudinal study
-
Ataga KI, Moore CG, Jones S, et al. Pulmonary hypertension in patients with sickle cell disease: a longitudinal study. Br J Haematol 2006;134:109–115.
-
(2006)
Br J Haematol
, vol.134
, pp. 109-115
-
-
Ataga, K.I.1
Moore, C.G.2
Jones, S.3
-
14
-
-
79961004549
-
Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity
-
Machado RF, Barst RJ, Yovetich NA, et al. Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity. Blood 2011;118:855–864.
-
(2011)
Blood
, vol.118
, pp. 855-864
-
-
Machado, R.F.1
Barst, R.J.2
Yovetich, N.A.3
-
15
-
-
84874541582
-
The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe
-
Nouraie M, Lee JS, Zhang Y, et al. The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe. Haematologica 2013;98:464–472.
-
(2013)
Haematologica
, vol.98
, pp. 464-472
-
-
Nouraie, M.1
Lee, J.S.2
Zhang, Y.3
-
16
-
-
0036908599
-
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease
-
Reiter CD, Wang X, Tanus-Santos JE, et al. Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nat Med 2002;8:1383–1389.
-
(2002)
Nat Med
, vol.8
, pp. 1383-1389
-
-
Reiter, C.D.1
Wang, X.2
Tanus-Santos, J.E.3
-
17
-
-
21444441271
-
Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease
-
Morris CR, Kato GJ, Poljakovic M, et al. Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease. JAMA 2005; 294:81–90.
-
(2005)
JAMA
, vol.294
, pp. 81-90
-
-
Morris, C.R.1
Kato, G.J.2
Poljakovic, M.3
-
18
-
-
0035909930
-
Oxygen radical inhibition of nitric oxide–dependent vascular function in sickle cell disease
-
Aslan M, Ryan TM, Adler B, et al. Oxygen radical inhibition of nitric oxide–dependent vascular function in sickle cell disease. Proc Natl Acad Sci USA 2001;98:15215–15220.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 15215-15220
-
-
Aslan, M.1
Ryan, T.M.2
Adler, B.3
-
19
-
-
33947605915
-
Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability
-
Hsu LL, Champion HC, Campbell-Lee SA, et al. Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability. Blood 2007;109:3088–3098.
-
(2007)
Blood
, vol.109
, pp. 3088-3098
-
-
Hsu, L.L.1
Champion, H.C.2
Campbell-Lee, S.A.3
-
20
-
-
44949212859
-
Protective effects of phosphodiesterase-4 (PDE-4) inhibition in the early phase of pulmonary arterial hypertension in transgenic sickle cell mice
-
De Franceschi L, Platt OS, Malpeli G, et al. Protective effects of phosphodiesterase-4 (PDE-4) inhibition in the early phase of pulmonary arterial hypertension in transgenic sickle cell mice. FASEB J 2008;22:1849–1860.
-
(2008)
FASEB J
, vol.22
, pp. 1849-1860
-
-
De Franceschi, L.1
Platt, O.S.2
Malpeli, G.3
-
21
-
-
0027252053
-
Sickle erythrocyteendothelial interactions in microcirculation: The role of von Willebrand factor and implications for vasoocclusion
-
Kaul DK, Nagel RL, Chen D, Tsai HM. Sickle erythrocyteendothelial interactions in microcirculation: the role of von Willebrand factor and implications for vasoocclusion. Blood 1993;81:2429–2438.
-
(1993)
Blood
, vol.81
, pp. 2429-2438
-
-
Kaul, D.K.1
Nagel, R.L.2
Chen, D.3
Tsai, H.M.4
-
22
-
-
0037423394
-
Nitric oxide–dependent generation of reactive species in sickle cell disease: Actin tyrosine induces defective cytoskeletal polymerization
-
Aslan M, Ryan TM, Townes TM, et al. Nitric oxide–dependent generation of reactive species in sickle cell disease: actin tyrosine induces defective cytoskeletal polymerization. J Biol Chem 2003;278:4194–4204.
-
(2003)
J Biol Chem
, vol.278
, pp. 4194-4204
-
-
Aslan, M.1
Ryan, T.M.2
Townes, T.M.3
-
23
-
-
24944572974
-
Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner
-
Isenberg JS, Ridnour LA, Perruccio EM, Espey MG, Wink DA, Roberts DD. Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner. Proc Natl Acad Sci USA 2005;102:13141–13146.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13141-13146
-
-
Isenberg, J.S.1
Ridnour, L.A.2
Perruccio, E.M.3
Espey, M.G.4
Wink, D.A.5
Roberts, D.D.6
-
24
-
-
33748747969
-
CD47 is necessary for inhibition of nitric oxide–stimulated vascular cell responses by thrombospondin-1
-
Isenberg JS, Ridnour LA, Dimitry J, Frazier WA, Wink DA, Roberts DD. CD47 is necessary for inhibition of nitric oxide–stimulated vascular cell responses by thrombospondin-1. J Biol Chem 2006;281:26069–26080.
-
(2006)
J Biol Chem
, vol.281
, pp. 26069-26080
-
-
Isenberg, J.S.1
Ridnour, L.A.2
Dimitry, J.3
Frazier, W.A.4
Wink, D.A.5
Roberts, D.D.6
-
25
-
-
84857982754
-
Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1
-
Bauer PM, Bauer EM, Rogers NM, et al. Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1. Cardiovasc Res 2012;93:682–693.
-
(2012)
Cardiovasc Res
, vol.93
, pp. 682-693
-
-
Bauer, P.M.1
Bauer, E.M.2
Rogers, N.M.3
-
26
-
-
84862810199
-
Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome, hydroxyurea therapy, and lower hemolytic rates
-
Novelli EM, Kato GJ, Ragni MV, et al. Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome, hydroxyurea therapy, and lower hemolytic rates. Am J Hematol 2012;87: 326–330.
-
(2012)
Am J Hematol
, vol.87
, pp. 326-330
-
-
Novelli, E.M.1
Kato, G.J.2
Ragni, M.V.3
-
27
-
-
57049137815
-
Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves
-
Lammers SR, Kao PH, Qi HJ, et al. Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves. Am J Physiol Heart Circ Physiol 2008;295:H1451–H1459.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
, pp. H1451-H1459
-
-
Lammers, S.R.1
Kao, P.H.2
Qi, H.J.3
-
28
-
-
77949729370
-
Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension
-
Rajkumar R, Konishi K, Richards TJ, et al. Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension. Am J Physiol Heart Circ Physiol 2010;298:H1235–H1248.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
, pp. H1235-H1248
-
-
Rajkumar, R.1
Konishi, K.2
Richards, T.J.3
-
29
-
-
84863717604
-
Pulmonary arterial hypertension: Classification and therapy with a focus on prostaglandin analogs
-
Papierniak ES, Lowenthal DT, Mubarak K. Pulmonary arterial hypertension: classification and therapy with a focus on prostaglandin analogs. Am J Ther 2012;19:300–314.
-
(2012)
Am J Ther
, vol.19
, pp. 300-314
-
-
Papierniak, E.S.1
Lowenthal, D.T.2
Mubarak, K.3
-
30
-
-
0346492721
-
The endothelin system in pulmonary arterial hypertension
-
Galiè N, Manes A, Branzi A. The endothelin system in pulmonary arterial hypertension. Cardiovasc Res 2004;61: 227–237.
-
(2004)
Cardiovasc Res
, vol.61
, pp. 227-237
-
-
Galiè, N.1
Manes, A.2
Branzi, A.3
-
31
-
-
84870523226
-
Molecular pathogenesis of pulmonary arterial hypertension
-
Rabinovitch M. Molecular pathogenesis of pulmonary arterial hypertension. J Clin Invest 2012;122:4306–4313.
-
(2012)
J Clin Invest
, vol.122
, pp. 4306-4313
-
-
Rabinovitch, M.1
-
32
-
-
84868024330
-
Altered expression and signal transduction of endothelin-1 receptors in heritable and idiopathic pulmonary arterial hypertension
-
Yu J, Taylor L, Wilson J, Comhair S, Erzurum S, Polgar P. Altered expression and signal transduction of endothelin-1 receptors in heritable and idiopathic pulmonary arterial hypertension. J Cell Physiol 2013;228:322–329.
-
(2013)
J Cell Physiol
, vol.228
, pp. 322-329
-
-
Yu, J.1
Taylor, L.2
Wilson, J.3
Comhair, S.4
Erzurum, S.5
Polgar, P.6
-
33
-
-
55249093143
-
Endothelial cell dysfunction and cross talk between endothelium and smooth muscle cells in pulmonary arterial hypertension
-
Humbert M, Montani D, Perros F, Dorfmüller P, Adnot S, Eddahibi S. Endothelial cell dysfunction and cross talk between endothelium and smooth muscle cells in pulmonary arterial hypertension. Vascul Pharmacol 2008;49: 113–118.
-
(2008)
Vascul Pharmacol
, vol.49
, pp. 113-118
-
-
Humbert, M.1
Montani, D.2
Perros, F.3
Dorfmüller, P.4
Adnot, S.5
Eddahibi, S.6
-
34
-
-
59449091909
-
Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses
-
Isenberg JS, Annis DS, Pendrak ML, et al. Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses. J Biol Chem 2009;284:1116–1125.
-
(2009)
J Biol Chem
, vol.284
, pp. 1116-1125
-
-
Isenberg, J.S.1
Annis, D.S.2
Pendrak, M.L.3
-
36
-
-
0028361796
-
Pulmonary arterial smooth muscle contractility in hypoxia-induced pulmonary hypertension
-
Griffith SL, Rhoades RA, Packer CS. Pulmonary arterial smooth muscle contractility in hypoxia-induced pulmonary hypertension. J Appl Physiol 1994;77:406–414.
-
(1994)
J Appl Physiol
, vol.77
, pp. 406-414
-
-
Griffith, S.L.1
Rhoades, R.A.2
Packer, C.S.3
-
37
-
-
40449108531
-
Thrombospondin-1: A physiological regulator of nitric oxide signaling
-
Isenberg JS, Frazier WA, Roberts DD. Thrombospondin-1: a physiological regulator of nitric oxide signaling. Cell Mol Life Sci 2008;65:728–742.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 728-742
-
-
Isenberg, J.S.1
Frazier, W.A.2
Roberts, D.D.3
-
38
-
-
77952861606
-
Thrombospondin-1 null mice are resistant to hypoxiainduced pulmonary hypertension
-
Ochoa CD, Yu L, Al-Ansari E, Hales CA, Quinn DA. Thrombospondin-1 null mice are resistant to hypoxiainduced pulmonary hypertension. J Cardiothorac Surg 2010; 5:32.
-
(2010)
J Cardiothorac Surg
, vol.5
, pp. 32
-
-
Ochoa, C.D.1
Yu, L.2
Al-Ansari, E.3
Hales, C.A.4
Quinn, D.A.5
-
39
-
-
84871217458
-
Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD 47
-
Soto-Pantoja DR, Stein EV, Rogers NM, Sharifi-Sanjani M, Isenberg JS, Roberts DD. Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD 47. Expert Opin Ther Targets 2013;17:89–103.
-
(2013)
Expert Opin Ther Targets
, vol.17
, pp. 89-103
-
-
Soto-Pantoja, D.R.1
Stein, E.V.2
Rogers, N.M.3
Sharifi-Sanjani, M.4
Isenberg, J.S.5
Roberts, D.D.6
-
40
-
-
0036084720
-
Upregulation of collagens detected by gene array in a model of flow-induced pulmonary vascular remodeling
-
Medhora M, Bousamra M 2nd, Zhu D, Somberg L, Jacobs ER. Upregulation of collagens detected by gene array in a model of flow-induced pulmonary vascular remodeling. Am J Physiol Heart Circ Physiol 2002;282:H414–H422.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.282
, pp. H414-H422
-
-
Medhora, M.1
Bousamra, M.2
Zhu, D.3
Somberg, L.4
Jacobs, E.R.5
-
41
-
-
0023585144
-
Mechanical properties and structure of isolated pulmonary arteries remodeled by chronic hyperoxia
-
Coflesky JT, Jones RC, Reid LM, Evans JN. Mechanical properties and structure of isolated pulmonary arteries remodeled by chronic hyperoxia. Am Rev Respir Dis 1987;136: 388–394.
-
(1987)
Am Rev Respir Dis
, vol.136
, pp. 388-394
-
-
Coflesky, J.T.1
Jones, R.C.2
Reid, L.M.3
Evans, J.N.4
-
42
-
-
79551475073
-
Nitrite in pulmonary arterial hypertension: Therapeutic avenues in the setting of dysregulated arginine/nitric oxide synthase signalling
-
Zuckerbraun BS, George P, Gladwin MT. Nitrite in pulmonary arterial hypertension: therapeutic avenues in the setting of dysregulated arginine/nitric oxide synthase signalling. Cardiovasc Res 2011;89:542–552.
-
(2011)
Cardiovasc Res
, vol.89
, pp. 542-552
-
-
Zuckerbraun, B.S.1
George, P.2
Gladwin, M.T.3
-
43
-
-
0036912721
-
Nitric oxide as a unique signaling molecule in the vascular system: A historical overview
-
Ignarro LJ. Nitric oxide as a unique signaling molecule in the vascular system: a historical overview. J Physiol Pharmacol 2002;53:503–514.
-
(2002)
J Physiol Pharmacol
, vol.53
, pp. 503-514
-
-
Ignarro, L.J.1
-
44
-
-
0028947405
-
The formation of peroxynitrite in vivo from nitric oxide and superoxide
-
Squadrito GL, Pryor WA. The formation of peroxynitrite in vivo from nitric oxide and superoxide. Chem Biol Interact 1995;96:203–206.
-
(1995)
Chem Biol Interact
, vol.96
, pp. 203-206
-
-
Squadrito, G.L.1
Pryor, W.A.2
-
45
-
-
84863738048
-
Molecular mechanisms of superoxide production by the mitochondrial respiratory chain
-
Drose S, Brandt U. Molecular mechanisms of superoxide production by the mitochondrial respiratory chain. Adv Exp Med Biol 2012;748:145–169.
-
(2012)
Adv Exp Med Biol
, vol.748
, pp. 145-169
-
-
Drose, S.1
Brandt, U.2
-
46
-
-
84855409770
-
Physiological roles of NOX/NADPH oxidase, the superoxide-generating enzyme
-
Katsuyama M, Matsuno K, Yabe-Nishimura C. Physiological roles of NOX/NADPH oxidase, the superoxide-generating enzyme. J Clin Biochem Nutr 2012;50:9–22.
-
(2012)
J Clin Biochem Nutr
, vol.50
, pp. 9-22
-
-
Katsuyama, M.1
Matsuno, K.2
Yabe-Nishimura, C.3
-
47
-
-
0037305699
-
The role of tetrahydrobiopterin in superoxide generation from eNOS: Enzymology and physiological implications
-
Vasquez-Vivar J, Kalyanaraman B, Martasek P. The role of tetrahydrobiopterin in superoxide generation from eNOS: enzymology and physiological implications. Free Radic Res 2003;37:121–127.
-
(2003)
Free Radic Res
, vol.37
, pp. 121-127
-
-
Vasquez-Vivar, J.1
Kalyanaraman, B.2
Martasek, P.3
-
48
-
-
0029926694
-
The release of nitric oxide and superoxide anion by neutrophils and mononuclear cells from patients with sickle cell anaemia
-
Dias-Da-Motta P, Arruda VR, Muscara MN, et al. The release of nitric oxide and superoxide anion by neutrophils and mononuclear cells from patients with sickle cell anaemia. Br J Haematol 1996;93:333–340.
-
(1996)
Br J Haematol
, vol.93
, pp. 333-340
-
-
Dias-Da-Motta, P.1
Arruda, V.R.2
Muscara, M.N.3
-
49
-
-
78649366858
-
Sickle cell disease serum induces NADPH enzyme subunit expression and oxidant production in leukocytes
-
Almeida CB, Franco-Penteado C, Saad ST, Costa FF, Conran N. Sickle cell disease serum induces NADPH enzyme subunit expression and oxidant production in leukocytes. Hematology 2010;15:422–429.
-
(2010)
Hematology
, vol.15
, pp. 422-429
-
-
Almeida, C.B.1
Franco-Penteado, C.2
Saad, S.T.3
Costa, F.F.4
Conran, N.5
-
50
-
-
0034925593
-
Tyrosine nitration: Localisation, quantification, consequences for protein function and signal transduction
-
Greenacre SA, Ischiropoulos H. Tyrosine nitration: localisation, quantification, consequences for protein function and signal transduction. Free Radic Res 2001;34:541–581.
-
(2001)
Free Radic Res
, vol.34
, pp. 541-581
-
-
Greenacre, S.A.1
Ischiropoulos, H.2
-
51
-
-
67649599147
-
Cellular and molecular basis of pulmonary arterial hypertension
-
Morrell NW, Adnot S, Archer SL, et al. Cellular and molecular basis of pulmonary arterial hypertension. J Am Coll Cardiol 2009;54:S20–S31.
-
(2009)
J am Coll Cardiol
, vol.54
, pp. S20-S31
-
-
Morrell, N.W.1
Adnot, S.2
Archer, S.L.3
-
52
-
-
75149192272
-
Nitric oxide, oxidative stress and inflammation in pulmonary arterial hypertension
-
Crosswhite P, Sun Z. Nitric oxide, oxidative stress and inflammation in pulmonary arterial hypertension. J Hypertens 2010;28:201–212.
-
(2010)
J Hypertens
, vol.28
, pp. 201-212
-
-
Crosswhite, P.1
Sun, Z.2
-
53
-
-
30144436179
-
Enhanced hypoxic pulmonary vasoconstriction in families of adults or children with idiopathic pulmonary arterial hypertension
-
Grunig E, Dehnert C, Mereles D, et al. Enhanced hypoxic pulmonary vasoconstriction in families of adults or children with idiopathic pulmonary arterial hypertension. Chest 2005; 128:630S–633S.
-
(2005)
Chest
, vol.128
, pp. 630S-633S
-
-
Grunig, E.1
Dehnert, C.2
Mereles, D.3
-
54
-
-
70949102039
-
Angiogenic and inflammatory markers of cardiopulmonary changes in children and adolescents with sickle cell disease
-
Niu X, Nouraie M, Campbell A, et al. Angiogenic and inflammatory markers of cardiopulmonary changes in children and adolescents with sickle cell disease. PloS ONE 2009; 4:e7956.
-
(2009)
Plos ONE
, vol.4
-
-
Niu, X.1
Nouraie, M.2
Campbell, A.3
-
55
-
-
0030751966
-
Influence of the nature of the porphyrin ligand on the nuclease activity of metalloporphyrin-oligonucleotide conjugates designed with cationic, hydrophobic or anionic metalloporphyrins
-
Mestre B, Pitie M, Loup C, Claparols C, Pratviel G, Meunier B. Influence of the nature of the porphyrin ligand on the nuclease activity of metalloporphyrin-oligonucleotide conjugates designed with cationic, hydrophobic or anionic metalloporphyrins. Nucleic Acids Res 1997;25:1022–1027.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 1022-1027
-
-
Mestre, B.1
Pitie, M.2
Loup, C.3
Claparols, C.4
Pratviel, G.5
Meunier, B.6
-
56
-
-
45749141769
-
Pulmonary arterial hypertension and left-sided heart disease in sickle cell disease: Clinical characteristics and association with soluble adhesion molecule expression
-
Klings ES, Anton Bland D, Rosenman D, et al. Pulmonary arterial hypertension and left-sided heart disease in sickle cell disease: clinical characteristics and association with soluble adhesion molecule expression. Am J Hematol 2008; 83:547–553.
-
(2008)
Am J Hematol
, vol.83
, pp. 547-553
-
-
Klings, E.S.1
Anton Bland, D.2
Rosenman, D.3
-
57
-
-
84902072922
-
Characterization of altered patterns of endothelial progenitor cells in sickle cell disease related pulmonary arterial hypertension
-
Anjum F, Lazar J, Zein J, Jamaleddine G, Demetis S, Wadgaonkar R. Characterization of altered patterns of endothelial progenitor cells in sickle cell disease related pulmonary arterial hypertension. Pulm Circ 2012;2:54–60.
-
(2012)
Pulm Circ
, vol.2
, pp. 54-60
-
-
Anjum, F.1
Lazar, J.2
Zein, J.3
Jamaleddine, G.4
Demetis, S.5
Wadgaonkar, R.6
-
58
-
-
77950587414
-
Segmentation and quantification of pulmonary artery for noninvasive CT assessment of sickle cell secondary pulmonary hypertension
-
Linguraru MG, Pura JA, Van Uitert RL, et al. Segmentation and quantification of pulmonary artery for noninvasive CT assessment of sickle cell secondary pulmonary hypertension. Med Phys 2010;37:1522–1532.
-
(2010)
Med Phys
, vol.37
, pp. 1522-1532
-
-
Linguraru, M.G.1
Pura, J.A.2
Van Uitert, R.L.3
-
59
-
-
80053300657
-
Echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United Kingdom
-
Sachdev V, Kato GJ, Gibbs JS, et al. Echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United Kingdom. Circulation 2011;124:1452–1460.
-
(2011)
Circulation
, vol.124
, pp. 1452-1460
-
-
Sachdev, V.1
Kato, G.J.2
Gibbs, J.S.3
-
60
-
-
34250160518
-
Hemodynamic and functional assessment of patients with sickle cell disease and pulmonary hypertension
-
Anthi A, Machado RF, Jison ML, et al. Hemodynamic and functional assessment of patients with sickle cell disease and pulmonary hypertension. Am J Respir Crit Care Med 2007;175:1272–1279.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 1272-1279
-
-
Anthi, A.1
Machado, R.F.2
Jison, M.L.3
-
61
-
-
84959341283
-
First successful lung transplantation for sickle cell disease with severe pulmonary arterial hypertension and pulmonary veno-occlusive disease
-
in this issue
-
George MP, Novelli EM, Shigemura N, et al. First successful lung transplantation for sickle cell disease with severe pulmonary arterial hypertension and pulmonary veno-occlusive disease. Pulm Circ 2013;3:952–958 (in this issue).
-
(2013)
Pulm Circ
, vol.3
, pp. 952-958
-
-
George, M.P.1
Novelli, E.M.2
Shigemura, N.3
-
62
-
-
0029089199
-
Sickle erythrocytes, after sickling, regulate the expression of the endothelin-1 gene and protein in human endothelial cells in culture
-
Phelan M, Perrine SP, Brauer M, Faller DV. Sickle erythrocytes, after sickling, regulate the expression of the endothelin-1 gene and protein in human endothelial cells in culture. J Clin Invest 1995;96:1145–1151.
-
(1995)
J Clin Invest
, vol.96
, pp. 1145-1151
-
-
Phelan, M.1
Perrine, S.P.2
Brauer, M.3
Faller, D.V.4
-
63
-
-
0032189829
-
Increased levels of endothelin-1 in plasma of sickle cell anemia patients
-
Rybicki AC, Benjamin LJ. Increased levels of endothelin-1 in plasma of sickle cell anemia patients. Blood 1998;92:2594–2596.
-
(1998)
Blood
, vol.92
, pp. 2594-2596
-
-
Rybicki, A.C.1
Benjamin, L.J.2
-
64
-
-
3042553343
-
Vasoactive factors in sickle cell disease: In vitro evidence for endothelin- 1-mediated vasoconstriction
-
Ergul S, Brunson CY, Hutchinson J, et al. Vasoactive factors in sickle cell disease: in vitro evidence for endothelin- 1-mediated vasoconstriction. Am J Hematol 2004;76:245–251.
-
(2004)
Am J Hematol
, vol.76
, pp. 245-251
-
-
Ergul, S.1
Brunson, C.Y.2
Hutchinson, J.3
-
65
-
-
85026313784
-
Role of thrombospondin-1 in pulmonary hypertension: A proof of concept [dissertation]
-
Frantz C. Role of thrombospondin-1 in pulmonary hypertension: a proof of concept [dissertation]. Universität des Saarlandes, 2011.
-
(2011)
Universität Des Saarlandes
-
-
Frantz, C.1
-
66
-
-
68549132471
-
Collagen-related gene and protein expression changes in the lung in response to chronic hypoxia
-
Estrada KD, Chesler NC. Collagen-related gene and protein expression changes in the lung in response to chronic hypoxia. Biomech Model Mechanobiol 2009;8:263–272.
-
(2009)
Biomech Model Mechanobiol
, vol.8
, pp. 263-272
-
-
Estrada, K.D.1
Chesler, N.C.2
-
67
-
-
0032446730
-
Alveolar hypoxia increases gene expression of extracellular matrix proteins and platelet-derived growth factor–B in lung parenchyma
-
Berg JT, Breen EC, Fu Z, Mathieu-Costello O, West JB. Alveolar hypoxia increases gene expression of extracellular matrix proteins and platelet-derived growth factor–B in lung parenchyma. Am J Respir Crit Care Med 1998;158: 1920–1928.
-
(1998)
Am J Respir Crit Care Med
, vol.158
, pp. 1920-1928
-
-
Berg, J.T.1
Breen, E.C.2
Fu, Z.3
Mathieu-Costello, O.4
West, J.B.5
-
68
-
-
78449286663
-
Redox signaling and reactive oxygen species in hypoxic pulmonary vasoconstriction
-
Fuchs B, Sommer N, Dietrich A, et al. Redox signaling and reactive oxygen species in hypoxic pulmonary vasoconstriction. Respir Physiol Neurobiol 2010;174:282–291.
-
(2010)
Respir Physiol Neurobiol
, vol.174
, pp. 282-291
-
-
Fuchs, B.1
Sommer, N.2
Dietrich, A.3
-
69
-
-
84870056994
-
Thrombospondin-1 regulates blood flow via CD47 receptor-mediated activation of NADPH oxidase 1
-
Csanyi G, Yao M, Rodriguez AI, et al. Thrombospondin-1 regulates blood flow via CD47 receptor-mediated activation of NADPH oxidase 1. Arterioscler Thromb Vasc Biol 2012; 32:2966–2973.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 2966-2973
-
-
Csanyi, G.1
Yao, M.2
Rodriguez, A.I.3
-
70
-
-
78149288324
-
Thrombospondin-1 supports blood pressure by limiting eNOS activation and endothelialdependent vasorelaxation
-
Bauer EM, Qin Y, Miller TW, et al. Thrombospondin-1 supports blood pressure by limiting eNOS activation and endothelialdependent vasorelaxation. Cardiovasc Res 2010;88:471–481.
-
(2010)
Cardiovasc Res
, vol.88
, pp. 471-481
-
-
Bauer, E.M.1
Qin, Y.2
Miller, T.W.3
-
71
-
-
33847372168
-
Thrombospondin-1 limits ischemic tissue survival by inhibiting nitric oxide–mediated vascular smooth muscle relaxation
-
Isenberg JS, Hyodo F, Matsumoto K, et al. Thrombospondin-1 limits ischemic tissue survival by inhibiting nitric oxide–mediated vascular smooth muscle relaxation. Blood 2007;109: 1945–1952.
-
(2007)
Blood
, vol.109
, pp. 1945-1952
-
-
Isenberg, J.S.1
Hyodo, F.2
Matsumoto, K.3
|