An IL-27/Lag3 axis enhances Foxp3+ regulatory T cell-suppressive function and therapeutic efficacy

Mucosal Immunology

Volumn 9, Issue 1, 2016, Pages 137-145

  Do, J S ^a   Visperas, A ^a,b   Sanogo, Y O ^a   Bechtel, J J ^a   Dvorina, N ^a   Kim, S ^a   Jang, E ^a   Stohlman, S A ^a   Shen, B ^a   Fairchild, R L ^a   Baldwin III, W M ^a   Vignali, D A A ^b,c   Min, B ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; INTERLEUKIN 27; LAG3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; CD223 ANTIGEN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; IL27 PROTEIN, MOUSE; INTERLEUKIN DERIVATIVE; INTERLEUKIN RECEPTOR; LEUKOCYTE ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL EXPANSION; COLITIS; CONTROLLED STUDY; DOWN REGULATION; FOXP3+ REGULATORY T CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH17 CELL; WILD TYPE; ANIMAL; C57BL MOUSE; CELL PROLIFERATION; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; PATHOLOGY; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD; CELL PROLIFERATION; COLITIS; DISEASE MODELS, ANIMAL; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKINS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PRIMARY CELL CULTURE; RECEPTORS, INTERLEUKIN; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY;

EID: 84953217393     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2015.45     Document Type: Article

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