A20 inhibits β-cell apoptosis by multiple mechanisms and predicts residual β-cell function in type 1 diabetes

Molecular Endocrinology

Volumn 30, Issue 1, 2016, Pages 48-61

  Fukaya, Makiko ^a   Brorsson, Caroline A ^b   Meyerovich, Kira ^a   Catrysse, Leen ^c,d   Delaroche, Diane ^a   Vanzela, Emerielle C ^a,e   Ortis, Fernanda ^f   Beyaert, Rudi ^c,d   Nielsen, Lotte B ^b   Andersen, Marie L ^b   Mortensen, Henrik B ^b   Pociot, Flemming ^b   van Loo, Geert ^c,d   Størling, Joachim ^b   Cardozo, Alessandra K ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d GHENT UNIVERSITY   (Belgium)

^e UNIVERSITY OF CAMPINAS   (Brazil)

^f UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; HEMOGLOBIN A1C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; PROTEIN A20; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; CYSTEINE PROTEINASE; SIGNAL PEPTIDE; TNFAIP3 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR ALPHA INDUCED PROTEIN 3;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL FATE; CELL FUNCTION; CELL SURVIVAL; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; GENE; GENE LOCUS; GENETIC RISK; GLYCEMIC CONTROL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; TNFAIP3 GENE; ANIMAL; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; CHILD; CYSTEINE ENDOPEPTIDASES; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INSULIN-SECRETING CELLS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; POLYMORPHISM, SINGLE NUCLEOTIDE; RATS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 3;

EID: 84953204319     PISSN: 08888809     EISSN: 19449917     Source Type: Journal    
DOI: 10.1210/me.2015-1176     Document Type: Article

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