메뉴 건너뛰기




Volumn 10, Issue 11, 2015, Pages

Renal lipotoxicity-associated inflammation and insulin resistance affects actin cytoskeleton organization in podocytes

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACETYL COENZYME A OXIDASE; CYCLOOXYGENASE 2; CYTOCHALASIN D; FAS ANTIGEN; FAT DROPLET; FIBROBLAST GROWTH FACTOR 21; GLUCOSE; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 4; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; INTERLEUKIN 6; MESSENGER RNA; NEPHRIN; OXIDOREDUCTASE; P CADHERIN; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PYRUVATE CARBOXYLASE; SERINE PALMITOYL TRANSFERASE 1; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TRANSFERASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VIMENTIN;

EID: 84952332569     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0142291     Document Type: Article
Times cited : (77)

References (69)
  • 1
    • 2342466734 scopus 로고    scopus 로고
    • Estimates for the year 2000 and projections for 2030
    • Wild. Estimates for the year 2000 and projections for 2030. World Health. 2004; 27: 1047-1053.
    • (2004) World Health , vol.27 , pp. 1047-1053
    • Wild1
  • 2
    • 33645100320 scopus 로고    scopus 로고
    • Risk Constellations in Patients with the Metabolic Syndrome: Epidemiology, Diagnosis, and Treatment Patterns
    • Haffner SM. Risk Constellations in Patients with the Metabolic Syndrome: Epidemiology, Diagnosis, and Treatment Patterns. Am J Med. Elsevier; 2015; 119: S3-S9. doi: 10.1016/j.amjmed.2006.01.008
    • (2015) Am J Med. Elsevier; , vol.119 , pp. S3-S9
    • Haffner, S.M.1
  • 3
    • 0020429608 scopus 로고    scopus 로고
    • Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial disease
    • Elsevier;
    • Moorhead JF, El-Nahas M, Chan MK, Varghese Z. Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial disease. Lancet. Elsevier; 2015; 320: 1309-1311. doi: 10.1016/S0140-6736 (82)91513-6
    • (2015) Lancet , vol.320 , pp. 1309-1311
    • Moorhead, J.F.1    El-Nahas, M.2    Chan, M.K.3    Varghese, Z.4
  • 4
    • 1442284350 scopus 로고    scopus 로고
    • Regulation of lipoprotein trafficking in the kidney: Role of inflammatory mediators and transcription factors
    • PMID: 14748720
    • Ruan XZ, Moorhead JF, Fernando R, Wheeler DC, Powis SH, Varghese Z. Regulation of lipoprotein trafficking in the kidney: role of inflammatory mediators and transcription factors. Biochem Soc Trans. 2004; 32: 88-91. doi: 10.1042/BST0320088 PMID: 14748720
    • (2004) Biochem Soc Trans , vol.32 , pp. 88-91
    • Ruan, X.Z.1    Moorhead, J.F.2    Fernando, R.3    Wheeler, D.C.4    Powis, S.H.5    Varghese, Z.6
  • 5
    • 0027989569 scopus 로고
    • Lipids and the kidney
    • PMID: 7996813
    • Ke Wf. Lipids and the kidney. Kidney Int. 1994; 46: 910-20. PMID: 7996813
    • (1994) Kidney Int , vol.46 , pp. 910-920
    • Ke, Wf.1
  • 6
    • 0347511753 scopus 로고    scopus 로고
    • Mediators of diabetic renal disease: The case for tgf-Beta as the major mediator
    • PMID: 14684674
    • Ziyadeh FN. Mediators of diabetic renal disease: the case for tgf-Beta as the major mediator. J Am Soc Nephrol. 2004; 15 Suppl 1: S55-S57. doi: 10.1097/01.ASN.0000093460.24823.5B PMID: 14684674
    • (2004) J Am Soc Nephrol , vol.15 , pp. S55-S57
    • Ziyadeh, F.N.1
  • 7
    • 84905378568 scopus 로고    scopus 로고
    • Podocyte pathology and nephropathy-sphingolipids in glomerular diseases
    • PMID: 25126087
    • Merscher S, Fornoni A. Podocyte pathology and nephropathy-sphingolipids in glomerular diseases. Frontiers in Endocrinology. 2014. doi: 10.3389/fendo.2014.00127 PMID: 25126087
    • (2014) Frontiers in Endocrinology
    • Merscher, S.1    Fornoni, A.2
  • 8
    • 0031788318 scopus 로고    scopus 로고
    • Differential Expression of Peroxisome Proliferator-Activated Receptor-α -β And -γ during Rat Embryonic Development
    • PMID: 9607781
    • Braissant O, Wahli W. Differential Expression of Peroxisome Proliferator-Activated Receptor-α, -β, and -γ during Rat Embryonic Development. Endocrinology. The Endocrine Society; 1998; 139: 2748-2754. doi: 10.1210/endo.139.6.6049 PMID: 9607781
    • (1998) Endocrinology. the Endocrine Society; , vol.139 , pp. 2748-2754
    • Braissant, O.1    Wahli, W.2
  • 9
    • 0032885996 scopus 로고    scopus 로고
    • LDL stimulates collagen mRNA synthesis in mesangial cells through induction of PKC and TGF-beta expression
    • PMID: 10484520
    • Lee HS, Kim BC, Hong HK, Kim YS. LDL stimulates collagen mRNA synthesis in mesangial cells through induction of PKC and TGF-beta expression. Am J Physiol. 1999; 277: F369-F376. PMID: 10484520
    • (1999) Am J Physiol , vol.277 , pp. F369-F376
    • Lee, H.S.1    Kim, B.C.2    Hong, H.K.3    Kim, Y.S.4
  • 10
    • 0034122443 scopus 로고    scopus 로고
    • Early mechanisms of renal injury in hypercholesterolemic or hypertriglyceridemic rats
    • PMID: 10752526
    • Joles J a, Kunter U, Janssen U, Kriz W, Rabelink TJ, Koomans H a, et al. Early mechanisms of renal injury in hypercholesterolemic or hypertriglyceridemic rats. J Am Soc Nephrol. 2000; 11: 669-683. PMID: 10752526
    • (2000) J Am Soc Nephrol , vol.11 , pp. 669-683
    • Joles, J.1    Kunter, U.2    Janssen, U.3    Kriz, W.4    Rabelink, T.J.5    Koomans, H.6
  • 11
    • 84455169599 scopus 로고    scopus 로고
    • The podocyte cytoskeleton-key to a functioning glomerulus in health and disease
    • Nature Publishing Group;
    • Welsh GI, Saleem M a. The podocyte cytoskeleton-key to a functioning glomerulus in health and disease. Nat Rev Nephrol. Nature Publishing Group; 2011; 8: 14-21. doi: 10.1038/nrneph.2011.151
    • (2011) Nat Rev Nephrol , vol.8 , pp. 14-21
    • Welsh, G.I.1    Saleem, M.2
  • 13
    • 77950515351 scopus 로고    scopus 로고
    • Genetics of nephrotic syndrome: Connecting molecular genetics to podocyte physiology
    • Machuca E, Benoit G, Antignac C. Genetics of nephrotic syndrome: Connecting molecular genetics to podocyte physiology. Hum Mol Genet. 2009; 18: 185-194. doi: 10.1093/hmg/ddp328
    • (2009) Hum Mol Genet , vol.18 , pp. 185-194
    • Machuca, E.1    Benoit, G.2    Antignac, C.3
  • 15
    • 0031563832 scopus 로고    scopus 로고
    • Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines
    • PMID: 9344605
    • Mundel P, Reiser J, Zúñiga Mejía Borja a, Pavenstädt H, Davidson GR, Kriz W, et al. Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines. Exp Cell Res. 1997; 236: 248-258. doi: 10.1006/excr.1997. 3739 PMID: 9344605
    • (1997) Exp Cell Res , vol.236 , pp. 248-258
    • Mundel, P.1    Reiser, J.2    Zúñiga Mejía Borja, A.3    Pavenstädt, H.4    Davidson, G.R.5    Kriz, W.6
  • 16
    • 55249115801 scopus 로고    scopus 로고
    • Therapeutic targets in focal and segmental glomerulosclerosis
    • PMID: 18660675
    • Lavin PJ, Gbadegesin R, Damodaran T V, Winn MP. Therapeutic targets in focal and segmental glomerulosclerosis. Curr Opin Nephrol Hypertens. 2008; 17: 386-392. doi: 10.1097/MNH. 0b013e32830464f4 PMID: 18660675
    • (2008) Curr Opin Nephrol Hypertens , vol.17 , pp. 386-392
    • Lavin, P.J.1    Gbadegesin, R.2    Damodaran, T.V.3    Winn, M.P.4
  • 17
    • 58149361842 scopus 로고    scopus 로고
    • Signaling in Regulation of Podocyte Phenotypes
    • PMID: 19142027
    • Chuang PY, He JC. Signaling in Regulation of Podocyte Phenotypes. Nephron Physiol. 2009; 111: p9-15. doi: 10.1159/000191075 PMID: 19142027
    • (2009) Nephron Physiol , vol.111 , pp. 9-15
    • Chuang, P.Y.1    He, J.C.2
  • 18
    • 33645733358 scopus 로고    scopus 로고
    • PATHOGENESIS of NONIMMUNE GLOMERULOPATHIES. Annu Rev Pathol Mech Dis
    • Kwoh C, Shannon MB, Miner JH, Shaw A. PATHOGENESIS OF NONIMMUNE GLOMERULOPATHIES. Annu Rev Pathol Mech Dis. Annual Reviews; 2006; 1: 349-374. doi: 10.1146/annurev.pathol. 1.110304.100119
    • (2006) Annual Reviews; , vol.1 , pp. 349-374
    • Kwoh, C.1    Shannon, M.B.2    Miner, J.H.3    Shaw, A.4
  • 19
    • 84920972821 scopus 로고    scopus 로고
    • Diabetic conditions downregulate the expression of CD2AP in podocytes via PI3-K/Akt signalling
    • PMID: 24846128
    • Ha T-S, Hong E-J, Han G-D. Diabetic conditions downregulate the expression of CD2AP in podocytes via PI3-K/Akt signalling. Diabetes Metab Res Rev. 2015; 31: 50-60. doi: 10.1002/dmrr.2562 PMID: 24846128
    • (2015) Diabetes Metab Res Rev , vol.31 , pp. 50-60
    • Ha, T.-S.1    Hong, E.-J.2    Han, G.-D.3
  • 20
    • 0036891810 scopus 로고    scopus 로고
    • Podocyte biology and response to injury
    • PMID: 12444221
    • Mundel P, Shankland SJ. Podocyte biology and response to injury. J Am Soc Nephrol. 2002; 13: 3005-3015. doi: 10.1097/01.ASN.0000039661.06947.FD PMID: 12444221
    • (2002) J Am Soc Nephrol , vol.13 , pp. 3005-3015
    • Mundel, P.1    Shankland, S.J.2
  • 21
    • 0037207471 scopus 로고    scopus 로고
    • Cell biology of the glomerular podocyte
    • PMID: 12506131
    • Pavenstädt H, Kriz W, Kretzler M. Cell biology of the glomerular podocyte. Physiol Rev. 2003; 83: 253-307. doi: 10.1152/physrev.00020.2002 PMID: 12506131
    • (2003) Physiol Rev , vol.83 , pp. 253-307
    • Pavenstädt, H.1    Kriz, W.2    Kretzler, M.3
  • 22
    • 84899153137 scopus 로고    scopus 로고
    • The Role of Survivin in Podocyte Injury Induced by Puromycin Aminonucleoside
    • PMID: 24747598
    • Li X, Zhang X, Li X, Ding F, Ding J. The Role of Survivin in Podocyte Injury Induced by Puromycin Aminonucleoside. Int J Mol Sci. 2014; 15: 6657-6673. doi: 10.3390/ijms15046657 PMID: 24747598
    • (2014) Int J Mol Sci , vol.15 , pp. 6657-6673
    • Li, X.1    Zhang, X.2    Li, X.3    Ding, F.4    Ding, J.5
  • 24
    • 34547742043 scopus 로고    scopus 로고
    • Actin filament organization of foot processes in vertebrate glomerular podocytes
    • PMID: 17605050
    • Ichimura K, Kurihara H, Sakai T. Actin filament organization of foot processes in vertebrate glomerular podocytes. Cell Tissue Res. 2007; 329: 541-557. doi: 10.1007/s00441-007-0440-4 PMID: 17605050
    • (2007) Cell Tissue Res , vol.329 , pp. 541-557
    • Ichimura, K.1    Kurihara, H.2    Sakai, T.3
  • 25
    • 0345282940 scopus 로고    scopus 로고
    • Actin filament organization of foot processes in rat podocytes
    • PMID: 14623927
    • Ichimura K, Kurihara H, Sakai T. Actin filament organization of foot processes in rat podocytes. J Histochem Cytochem. United States; 2003; 51: 1589-1600. PMID: 14623927
    • (2003) J Histochem Cytochem. United States; , vol.51 , pp. 1589-1600
    • Ichimura, K.1    Kurihara, H.2    Sakai, T.3
  • 28
    • 0026047651 scopus 로고
    • Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse
    • PMID: 1711218
    • Jat PS, Noble MD, Ataliotis P, Tanaka Y, Yannoutsos N, Larsen L, et al. Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse. Proc Natl Acad Sci U S A. 1991; 88: 5096-5100. doi: 10.1073/pnas.88.12.5096 PMID: 1711218
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 5096-5100
    • Jat, P.S.1    Noble, M.D.2    Ataliotis, P.3    Tanaka, Y.4    Yannoutsos, N.5    Larsen, L.6
  • 29
    • 0033588253 scopus 로고    scopus 로고
    • Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate
    • PMID: 10446195
    • Schmitz-Peiffer C, Craig DL, Biden TJ. Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate. J Biol Chem. 1999; 274: 24202-24210. doi: 10.1074/jbc.274.34.24202 PMID: 10446195
    • (1999) J Biol Chem , vol.274 , pp. 24202-24210
    • Schmitz-Peiffer, C.1    Craig, D.L.2    Biden, T.J.3
  • 30
  • 31
    • 33645459493 scopus 로고    scopus 로고
    • Permselective dysfunction of podocyte-podocyte contact upon angiotensin II unravels the molecular target for renoprotective intervention
    • PMID: 16565484
    • Daniela Macconi and GR. Permselective dysfunction of podocyte-podocyte contact upon angiotensin II unravels the molecular target for renoprotective intervention. Am J Pathol. 2006; 168: 1073-85. PMID: 16565484
    • (2006) Am J Pathol , vol.168 , pp. 1073-1085
    • Daniela Macconi, G.R.1
  • 32
    • 84855164474 scopus 로고    scopus 로고
    • Early Peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass
    • PMID: 22208362
    • Vivas Y, Martinez-Garcia C, Izquierdo A, Garcia-Garcia F, Callejas S, Velasco I, et al. Early Peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass. BMC Med Genomics. BioMed Central Ltd; 2011; 4: 86. doi: 10.1186/1755-8794-4-86 PMID: 22208362
    • (2011) BMC Med Genomics. BioMed Central Ltd; , vol.4 , pp. 86
    • Vivas, Y.1    Martinez-Garcia, C.2    Izquierdo, A.3    Garcia-Garcia, F.4    Callejas, S.5    Velasco, I.6
  • 33
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • MM B
    • MM B. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976; 7: 248-54.
    • (1976) Anal Biochem , vol.7 , pp. 248-254
  • 34
    • 67650689332 scopus 로고    scopus 로고
    • The monocyte chemoattractant protein-1/CCR2 loop, inducible by TGF-beta, increases podocyte motility and albumin permeability
    • PMID: 19420107
    • Lee EY, Chung CH, Khoury CC, Yeo TK, Pyagay PE, Wang A, et al. The monocyte chemoattractant protein-1/CCR2 loop, inducible by TGF-beta, increases podocyte motility and albumin permeability. Am J Physiol Renal Physiol. 2009; 297: F85-F94. doi: 10.1152/ajprenal.90642.2008 PMID: 19420107
    • (2009) Am J Physiol Renal Physiol , vol.297 , pp. F85-F94
    • Lee, E.Y.1    Chung, C.H.2    Khoury, C.C.3    Yeo, T.K.4    Pyagay, P.E.5    Wang, A.6
  • 35
    • 0035496907 scopus 로고    scopus 로고
    • Decorin inhibits macrophage colony-stimulating factor proliferation of macrophages and enhances cell survival through induction of p27Kip1 and p21Waf1
    • PMID: 11567999
    • Xaus J, Comalada M, Cardó M, Valledor AF, Celada A. Decorin inhibits macrophage colony-stimulating factor proliferation of macrophages and enhances cell survival through induction of p27Kip1 and p21Waf1. Blood. 2001; 98: 2124-2133. doi: 10.1182/blood.V98.7.2124 PMID: 11567999
    • (2001) Blood , vol.98 , pp. 2124-2133
    • Xaus, J.1    Comalada, M.2    Cardó, M.3    Valledor, A.F.4    Celada, A.5
  • 36
    • 29244448978 scopus 로고    scopus 로고
    • Increased Superoxide Anion Production by Interleukin-1 beta Impairs Nitric Oxide-Mediated Relaxation in Resistance Arteries
    • Jiménez-Altayó F, Briones a. M, Giraldo J, Planas a. M, Salaices M, Vila E. Increased Superoxide Anion Production by Interleukin-1 beta Impairs Nitric Oxide-Mediated Relaxation in Resistance Arteries. J Pharmacol. 2006; 316: 42-52. doi: 10.1124/jpet.105.088435.to
    • (2006) J Pharmacol , vol.316 , pp. 42-52
    • Jiménez-Altayó, F.1    Briones, A.M.2    Giraldo, J.3    Planas, A.M.4    Salaices, M.5    Vila, E.6
  • 37
    • 33748069813 scopus 로고    scopus 로고
    • Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
    • PMID: 16931765
    • Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO, et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science. United States; 2006; 313: 1137-1140. doi: 10.1126/science.1128294 PMID: 16931765
    • (2006) Science. United States; , vol.313 , pp. 1137-1140
    • Ozcan, U.1    Yilmaz, E.2    Ozcan, L.3    Furuhashi, M.4    Vaillancourt, E.5    Smith, R.O.6
  • 38
    • 84924371283 scopus 로고    scopus 로고
    • Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy
    • Nature Publishing Group; PMID: 25754093
    • Madhusudhan T, Wang H, Dong W, Ghosh S, Bock F, Thangapandi VR, et al. Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy. Nat Commun. Nature Publishing Group; 2015; 6: 6496. doi: 10.1038/ncomms7496 PMID: 25754093
    • (2015) Nat Commun , vol.6 , pp. 6496
    • Madhusudhan, T.1    Wang, H.2    Dong, W.3    Ghosh, S.4    Bock, F.5    Thangapandi, V.R.6
  • 39
    • 0346106235 scopus 로고    scopus 로고
    • The role of p42/44 MAPK and protein kinase B in connective tissue growth factor induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells
    • PMID: 12218048
    • Crean JKG, Finlay D, Murphy M, Moss C, Godson C, Martin F, et al. The role of p42/44 MAPK and protein kinase B in connective tissue growth factor induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells. J Biol Chem. 2002; 277: 44187-44194. doi: 10.1074/jbc.M203715200 PMID: 12218048
    • (2002) J Biol Chem , vol.277 , pp. 44187-44194
    • Crean, J.K.G.1    Finlay, D.2    Murphy, M.3    Moss, C.4    Godson, C.5    Martin, F.6
  • 40
    • 77957657608 scopus 로고    scopus 로고
    • Insulin signaling to the glomerular podocyte is critical for normal kidney function
    • Welsh GI, Hale LJ, Eremina V, Jeansson M, Maezawa Y, Lennon R, et al. Insulin signaling to the glomerular podocyte is critical for normal kidney function. Cell Metab. United States; 2010; 12: 329-340. doi: 10.1016/j.cmet.2010.08.015
    • (2010) Cell Metab. United States; , vol.12 , pp. 329-340
    • Welsh, G.I.1    Hale, L.J.2    Eremina, V.3    Jeansson, M.4    Maezawa, Y.5    Lennon, R.6
  • 42
    • 84903551813 scopus 로고    scopus 로고
    • Lipid biology of the podocyte-new perspectives offer new opportunities
    • PMID: 24861084
    • Katz H, Fornoni A, Merscher S, Kopp JB. Lipid biology of the podocyte-new perspectives offer new opportunities. Nat Rev Nephrol. 2014; 10: 379-388. doi: 10.1038/nrneph.2014.87 PMID: 24861084
    • (2014) Nat Rev Nephrol , vol.10 , pp. 379-388
    • Katz, H.1    Fornoni, A.2    Merscher, S.3    Kopp, J.B.4
  • 43
    • 34948821093 scopus 로고    scopus 로고
    • Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet
    • PMID: 17855643
    • Kume S, Uzu T, Araki S, Sugimoto T, Isshiki K, Chin-Kanasaki M, et al. Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet. J Am Soc Nephrol. 2007; 18: 2715-2723. doi: 10.1681/ASN.2007010089 PMID: 17855643
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2715-2723
    • Kume, S.1    Uzu, T.2    Araki, S.3    Sugimoto, T.4    Isshiki, K.5    Chin-Kanasaki, M.6
  • 45
    • 84856723000 scopus 로고    scopus 로고
    • The MCP-1/CCR2 axis in podocytes is involved in apoptosis induced by diabetic conditions
    • PMID: 22006533
    • Nam BY, Paeng J, Kim SH, Lee SH, Kim DH, Kang HY, et al. The MCP-1/CCR2 axis in podocytes is involved in apoptosis induced by diabetic conditions. Apoptosis. 2012; 17: 1-13. doi: 10.1007/s10495- 011-0661-6 PMID: 22006533
    • (2012) Apoptosis , vol.17 , pp. 1-13
    • Nam, B.Y.1    Paeng, J.2    Kim, S.H.3    Lee, S.H.4    Kim, D.H.5    Kang, H.Y.6
  • 46
    • 51349156218 scopus 로고    scopus 로고
    • Insulin sensitivity: Modulation by nutrients and inflammation
    • PMID: 18769626
    • Schenk S, Saberi M, Olefsky JM. Insulin sensitivity: Modulation by nutrients and inflammation. J Clin Invest. 2008; 118: 2992-3002. doi: 10.1172/JCI34260 PMID: 18769626
    • (2008) J Clin Invest , vol.118 , pp. 2992-3002
    • Schenk, S.1    Saberi, M.2    Olefsky, J.M.3
  • 47
    • 33745861300 scopus 로고    scopus 로고
    • Review series Inflammation and insulin resistance
    • PMID: 16823477
    • Shoelson SE, Lee J, Goldfine AB. Review series Inflammation and insulin resistance. J Clin Invest. 2006; 116: 1793-1801. doi: 10.1172/JCI29069.and PMID: 16823477
    • (2006) J Clin Invest , vol.116 , pp. 1793-1801
    • Shoelson, S.E.1    Lee, J.2    Goldfine, A.B.3
  • 48
    • 0028795359 scopus 로고
    • Metabolic effects of fatty acid-bearing albumin on a proximal tubule cell line
    • Thomas ME, Morrison AR, Schreiner GF. Metabolic effects of fatty acid-bearing albumin on a proximal tubule cell line. Am J Physiol-Ren Physiol. 1995; 268: F1177-F1184. Available: http://ajprenal. physiology.org/content/268/6/F1177.abstract
    • (1995) Am J Physiol-Ren Physiol , vol.268 , pp. F1177-F1184
    • Thomas, M.E.1    Morrison, A.R.2    Schreiner, G.F.3
  • 50
    • 0036783939 scopus 로고    scopus 로고
    • Fatty acids exacerbate tubulointerstitial injury in protein-overload proteinuria
    • PMID: 12217854
    • Thomas ME, Harris KPG, Walls J, Furness PN, Brunskill NJ. Fatty acids exacerbate tubulointerstitial injury in protein-overload proteinuria. Am J Physiol Renal Physiol. 2002; 283: F640-F647. doi: 10. 1152/ajprenal.00001.2002 PMID: 12217854
    • (2002) Am J Physiol Renal Physiol , vol.283 , pp. F640-F647
    • Thomas, M.E.1    Harris, K.P.G.2    Walls, J.3    Furness, P.N.4    Brunskill, N.J.5
  • 51
    • 3442895916 scopus 로고    scopus 로고
    • Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes
    • PMID: 15143153
    • Gao Z, Zhang X, Zuberi A, Hwang D, Quon MJ, Lefevre M, et al. Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes. Mol Endocrinol. 2004; 18: 2024-2034. doi: 10.1210/me.2003-0383 PMID: 15143153
    • (2004) Mol Endocrinol , vol.18 , pp. 2024-2034
    • Gao, Z.1    Zhang, X.2    Zuberi, A.3    Hwang, D.4    Quon, M.J.5    Lefevre, M.6
  • 52
    • 77956921023 scopus 로고    scopus 로고
    • The effects of palmitate on hepatic insulin resistance are mediated by NADPH oxidase 3-derived reactive oxygen species through JNK and p38 MAPK pathways
    • PMID: 20647313
    • Gao D, Nong S, Huang X, Lu Y, Zhao H, Lin Y, et al. The effects of palmitate on hepatic insulin resistance are mediated by NADPH oxidase 3-derived reactive oxygen species through JNK and p38 MAPK pathways. J Biol Chem. 2010; 285: 29965-29973. doi: 10.1074/jbc.M110.128694 PMID: 20647313
    • (2010) J Biol Chem , vol.285 , pp. 29965-29973
    • Gao, D.1    Nong, S.2    Huang, X.3    Lu, Y.4    Zhao, H.5    Lin, Y.6
  • 54
    • 33748755008 scopus 로고    scopus 로고
    • Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes
    • PMID: 16798732
    • Senn JJ. Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes. J Biol Chem. 2006; 281: 26865-26875. doi: 10.1074/jbc.M513304200 PMID: 16798732
    • (2006) J Biol Chem , vol.281 , pp. 26865-26875
    • Senn, J.J.1
  • 55
    • 0242580711 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) Induces Insulin Resistance in 3T3-L1 Adipocytes and Is, Like IL-8 and Tumor Necrosis Factor-α, Overexpressed in Human Fat Cells from Insulin-resistant Subjects
    • PMID: 12952969
    • Rotter V, Nagaev I, Smith U. Interleukin-6 (IL-6) Induces Insulin Resistance in 3T3-L1 Adipocytes and Is, Like IL-8 and Tumor Necrosis Factor-α, Overexpressed in Human Fat Cells from Insulin-resistant Subjects. J Biol Chem. 2003; 278: 45777-45784. doi: 10.1074/jbc.M301977200 PMID: 12952969
    • (2003) J Biol Chem , vol.278 , pp. 45777-45784
    • Rotter, V.1    Nagaev, I.2    Smith, U.3
  • 56
    • 79959215013 scopus 로고    scopus 로고
    • IRS2 and PTP1B: Two opposite modulators of hepatic insulin signalling
    • PMID: 21401320
    • Valverde AM, González-Rodríguez A. IRS2 and PTP1B: Two opposite modulators of hepatic insulin signalling. Arch Physiol Biochem. 2011; 117: 105-115. doi: 10.3109/13813455.2011.557386 PMID: 21401320
    • (2011) Arch Physiol Biochem , vol.117 , pp. 105-115
    • Valverde, A.M.1    González-Rodríguez, A.2
  • 58
    • 84880149950 scopus 로고    scopus 로고
    • Glomerular podocyte Insulin directly stimulates VEGF-A production in the Insulin directly stimulates VEGF-A production in the glomerular podocyte
    • Hale LJ, Mathieson W, Welsh GI, Coward RJ, Hurcombe J, Lay A, et al. glomerular podocyte Insulin directly stimulates VEGF-A production in the Insulin directly stimulates VEGF-A production in the glomerular podocyte. Am J Physiol Ren Physiol. 2013; 305: 182-188. doi: 10.1152/ajprenal.00548.2012
    • (2013) Am J Physiol Ren Physiol , vol.305 , pp. 182-188
    • Hale, L.J.1    Mathieson, W.2    Welsh, G.I.3    Coward, R.J.4    Hurcombe, J.5    Lay, A.6
  • 59
    • 84857539784 scopus 로고    scopus 로고
    • Effect of intracellular lipid accumulation in a new model of nonalcoholic fatty liver disease
    • PMID: 22380754
    • Chavez-Tapia NC, Rosso N, Tiribelli C. Effect of intracellular lipid accumulation in a new model of nonalcoholic fatty liver disease. BMC Gastroenterol. BioMed Central Ltd; 2012; 12: 20. doi: 10.1186/1471- 230X-12-20 PMID: 22380754
    • (2012) BMC Gastroenterol. BioMed Central Ltd; , vol.12 , pp. 20
    • Chavez-Tapia, N.C.1    Rosso, N.2    Tiribelli, C.3
  • 60
    • 11144278530 scopus 로고    scopus 로고
    • Redox regulation of nerve growth factor-induced neuronal differentiation of PC12 cells through modulation of the nerve growth factor receptor TrkA
    • PMID: 15629104
    • Kamata H, Oka S, Shibukawa Y, Kakuta J HH. Redox regulation of nerve growth factor-induced neuronal differentiation of PC12 cells through modulation of the nerve growth factor receptor, TrkA. Arch Biochem Biophys. 2005; 434: 16-25. PMID: 15629104
    • (2005) Arch Biochem Biophys , vol.434 , pp. 16-25
    • Kamata, H.1    Oka, S.2    Shibukawa, Y.3    Kakuta, J.H.H.4
  • 61
    • 59149084125 scopus 로고    scopus 로고
    • Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes
    • PMID: 18971923
    • Ijaz A, Tejada T, Catanuto P, Xia X, Elliot SJ, Lenz O, et al. Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes. Kidney Int. 2009; 75: 381-388. doi: 10.1038/ki.2008.559 PMID: 18971923
    • (2009) Kidney Int , vol.75 , pp. 381-388
    • Ijaz, A.1    Tejada, T.2    Catanuto, P.3    Xia, X.4    Elliot, S.J.5    Lenz, O.6
  • 62
    • 77954579285 scopus 로고    scopus 로고
    • Decrease in membrane phospholipid unsaturation induces unfolded protein response
    • PMID: 20489212
    • Ariyama H, Kono N, Matsuda S, Inoue T, Arai H. Decrease in membrane phospholipid unsaturation induces unfolded protein response. J Biol Chem. 2010; 285: 22027-22035. doi: 10.1074/jbc.M110. 126870 PMID: 20489212
    • (2010) J Biol Chem , vol.285 , pp. 22027-22035
    • Ariyama, H.1    Kono, N.2    Matsuda, S.3    Inoue, T.4    Arai, H.5
  • 63
    • 77957255986 scopus 로고    scopus 로고
    • Fatty acid-induced oxidation and triglyceride formation is higher in insulin-producing MIN6 cells exposed to oleate compared to palmitate
    • Wiley Subscription Services, Inc., A Wiley Company; PMID: 20524206
    • Thörn K, Bergsten P. Fatty acid-induced oxidation and triglyceride formation is higher in insulin-producing MIN6 cells exposed to oleate compared to palmitate. J Cell Biochem. Wiley Subscription Services, Inc., A Wiley Company; 2010; 111: 497-507. doi: 10.1002/jcb.22734 PMID: 20524206
    • (2010) J Cell Biochem , vol.111 , pp. 497-507
    • Thörn, K.1    Bergsten, P.2
  • 65
    • 20544465220 scopus 로고    scopus 로고
    • Nephrotic plasma alters slit diaphragm- dependent signaling and translocates nephrin, Podocin, and CD2 associated protein in cultured human podocytes
    • PMID: 15659563
    • Coward RJM, Foster RR, Patton D, Ni L, Lennon R, Bates DO, et al. Nephrotic plasma alters slit diaphragm- dependent signaling and translocates nephrin, Podocin, and CD2 associated protein in cultured human podocytes. J Am Soc Nephrol. 2005; 16: 629-637. doi: 10.1681/ASN.2004030172 PMID: 15659563
    • (2005) J Am Soc Nephrol , vol.16 , pp. 629-637
    • Coward, R.J.M.1    Foster, R.R.2    Patton, D.3    Ni, L.4    Lennon, R.5    Bates, D.O.6
  • 67
    • 0034957257 scopus 로고    scopus 로고
    • Affecting the decline of renal function in diabetes mellitus
    • PMID: 11422776
    • Steffes MW. Affecting the decline of renal function in diabetes mellitus. Kidney Int. 2001; 60: 378-379. doi: 10.1046/j.1523-1755.2001.00812.x PMID: 11422776
    • (2001) Kidney Int , vol.60 , pp. 378-379
    • Steffes, M.W.1
  • 68
    • 2642515740 scopus 로고    scopus 로고
    • Disruption of the actin cytoskeleton results in nuclear factor-κB activation and inflammatory mediator production in cultured human intestinal epithelial cells
    • Wiley Subscription Services, Inc., A Wiley Company; PMID: 15137059
    • Németh ZH, Deitch EA, Davidson MT, Szabó C, Vizi ES, Haskó G. Disruption of the actin cytoskeleton results in nuclear factor-κB activation and inflammatory mediator production in cultured human intestinal epithelial cells. J Cell Physiol. Wiley Subscription Services, Inc., A Wiley Company; 2004; 200: 71-81. doi: 10.1002/jcp.10477 PMID: 15137059
    • (2004) J Cell Physiol , vol.200 , pp. 71-81
    • Németh, Z.H.1    Deitch, E.A.2    Davidson, M.T.3    Szabó, C.4    Vizi, E.S.5    Haskó, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.