The role of Survivin in podocyte injury induced by puromycin aminonucleoside

International Journal of Molecular Sciences

Volumn 15, Issue 4, 2014, Pages 6657-6673

  Li, Xuejuan ^a   Zhang, Xiaoyan ^a   Li, Xiaoyan ^a   Ding, Fangrui ^a   Ding, Jie ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

Author keywords

Cyto protection; Nephropathy; Podocyte apoptosis; Survivin

Indexed keywords

CASPASE 3; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PUROMYCIN AMINONUCLEOSIDE; SMALL INTERFERING RNA; SURVIVIN; ANTINEOPLASTIC ANTIBIOTIC; BIRC5 PROTEIN, MOUSE; INHIBITOR OF APOPTOSIS PROTEIN; REPRESSOR PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; FLUORESCENCE MICROSCOPY; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; KIDNEY INJURY; MOUSE; NICK END LABELING; NONHUMAN; PODOCYTE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ACTIN FILAMENT; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CONFOCAL MICROSCOPY; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; RNA INTERFERENCE;

ACTIN CYTOSKELETON; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CASPASE 3; CELLS, CULTURED; INHIBITOR OF APOPTOSIS PROTEINS; MICE; MICROSCOPY, CONFOCAL; PODOCYTES; PUROMYCIN AMINONUCLEOSIDE; REPRESSOR PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84899153137     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms15046657     Document Type: Article

References (55)

1. Li, F. Survivin study: What is the next wave? J. Cell Physiol. 2003, 197, 8-29.
2. Li, F.; Ling, X. Survivin study: An update of "What is the next wave?" J. Cell Physiol. 2006, 208, 476-486.
3. Ambrosini, G.; Adida, C.; Altieri, D.C. A noble anti-apoptotic gene, survivin, is expressed in cancer and lymphoma. Nat. Med. 1997, 3, 917-921.
4. Shariat, S.F.; Lotan, Y.; Saboorian, H.; Khoddami, S.M.; Roehrborn, C.G., Slawin, K.M.; Ashfaq, R. Survivin expression is associated with features of biologically aggressive prostate carcinoma. Cancer 2004, 100, 751-757.
5. Sohn, D.M.; Kim, S.Y.; Baek, M.J.; Lim, C.W.; Lee, M.H.; Cho, M.S.; Kim, T.Y. Expression of survivin and clinical correlation in patients with breast cancer. Biomed. Pharmacother. 2006, 60, 289-292.
6. Sarela, A.I.; Verveke, C.S.; Ramsdale, J.; Davis, C.I.; Markham, A.F.; Guillou, P.J. Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma. Br. J. Cancer 2002, 86, 886-892.
7. Lu, C.D.; Altieri, D.C.; Tanigawa, N. Expression of novel antiapoptotic gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas. Cancer Res. 1998, 58, 1808-1812.
8. Okada, E.; Murai, Y.; Matsui, K.; Isizawa, S.; Cheng, C.; Masuda, M.; Takano, Y. Survivin expression in tumor cell nuclei is predictive of favorable prognosis in gastric cancer patients, Cancer Lett. 2001, 163, 109-116.
9. Li, F.; Ling, X.; Huang, H.; Brattain, L.; Apontes, P.; Wu, J.; Binderup, L.; Brattain, M.G. Differential expression of survivin and apoptosis by vitamin D3 in two isogenic MCF-7 breast cancer cell sublines. Oncogene 2005, 24, 1385-1395.
10. Tamm, I.; Wang, Y.; Sausville, E.; Scudiero, D.A.; Vigna, N.; Oltersdorf, T.; Reed, J.C. IAP-family protein surviving inhibitoes caspase activity and apoptosis induced by Fas (CD95), Bax, caspase, and anticancer drugs. Cancer Res. 1998, 58, 5315-5320.
11. Shin, S.; Sung, B.J.; Cho, Y.S.; Kim, H.J.; Ha, N.C.; Hwang, J.I.; Chung, C.W.; Jung, Y.K.; Oh, B.H. An antiapoptotic protein human surviving is a direct inhibitor of caspase 3 and 7. Biochemistry 2001, 40, 1117-1123.
12. Dohi, T.; Beltrami, E.; Wall, N.R.; Plescia, J.; Altieri, D.C. Mitochondrial surviving inhibors apoptosis and promotes tumorigenesis. J. Clin. Investig. 2004, 114, 1117-1127.
13. Altieri, D.C. Survivin and IAP proteins in cell-death mechanisms. Biochem. J. 2010, 430, 199-205.
14. Altieri, D.C. Survivin in apoptosis control and cell cycleregulation in cancer. Prog. Cell Cycle Res. 2003, 3, 447-452.
15. Waligórska-Stachura, J.; Jankowska, A.; Waśko, R.; Liebert, W.; Biczysko, M.; Czarnywojtek, A.; Baszko-Błaszyk, D.; Shimek, V.; Ruchała, M. Survivin-Prognostic tumor biomarker in human neoplasms-Review. Ginekol. Pol. 2012, 83, 537-540.
16. Rödel, F.; Sprenger, T.; Kaina, B.; Liersch, T.; Rödel, C.; Fulda, S.; Hehlgans, S. Survivin as a prognostic/predictive marker and molecular target in cancer therapy. Curr. Med. Chem. 2012, 19, 3679-3688.
17. Uren, A.G.; Wong, L.; Pakusch, M.; Fowler, K.J.; Burrows, F.J.; Vaux, D.L.; Choo, K.H. Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype. Curr. Biol. 2000, 10, 1319-1328.
18. Li, F.; Ambrosini, G.; Chu, E.Y.; Plescia, J.; Tognin, S.; Marchisio, P.C.; Altieri, D.C. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 1998, 396, 580-584.
19. Dallaglio, K.; Marconi, A.; Pincelli, C. Survivin: A dual player in healthy and diseased skin. J. Investig. Dermatol. 2012, 132, 18-27.
20. Xing, Z.; Conway, E.M.; Kang, C.; Winoto, A. Essential role of survivin, an inhibitor of apoptosis protein, in T cell development, maturation, and homeostasis. J. Exp. Med. 2004, 199, 69-80.
21. Okada, H.; Bakal, C.; Shahinian, A.; Elia, A.; Wakeham, A.; Suh, W.K.; Duncan, G.S.; Ciofani, M.; Rottapel, R.; Zuniga-Pflucker, J.C, et al. Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death. J. Exp. Med. 2004, 199, 399-410.
22. Chiou, S.K.; Moon, W.S.; Jones, M.K.; Tarnawski, A.S. Survivin expression in the stomach: Implications for mucosal integrity and protection. Biochem. Biophys. Res. Commun. 2003, 305, 374-379.
23. Kindt, N.; Menzebach, A.; van de Wouwer, M.; Betz, I.; de Vriese, A.; Conway, E.M. Protective role of the inhibitor of apoptosis protein, survivin, in toxin-induced acute renal failure. FASEB. J. 2008, 22, 510-521.
24. Lechler, P.; Wu, X.; Bernhardt, W.; Campean, V.; Gastiger, S.; Hackenbeck, T.; Klanke, B.; Weidemann, A.; Warnecke, C.; Amann, K, et al. The tumor gene survivin is highly expressed in adult renal tubular cells: Implications for a pathophysiological role in the kidney. Am. J. Pathol. 2007, 171, 1483-1498.
25. Santini, D.; Abbate, A.; Scarpa, S.; Vasaturo, F.; Biondi-Zoccai, G.G.; Bussani, R.; de Giorgio, F.; Bassan, F.; Camilot, D.; di Marino, M.P., et al. Surviving acute myocardial infarction: Survivin expression in viable cardiomyocytes after infarction. J. Clin. Pathol. 2004, 57, 1321-1324.
26. Abbate, A.; Scarpa, S.; Santini, D.; Palleiro, J.; Vasaturo, F.; Miller, J.; Morales, C.; Vetrovec, G.W.; Baldi, A. Myocardial expression of survivin, an apoptosis inhibitor, in aging and heart failure: An experimental study in the spontaneously hypertensive rat. Int. J. Cardiol. 2006, 113, 371-376.
27. Conway, E.M.; Zwerts, F.; van Eygen, V.; DeVriese, A.; Nagai, N.; Luo, W.; Collen, D. Survivin-dependent angiogenesis in ischemic brain: Molecular mechanisms of hypoxia-induced up-regulation. Am. J. Pathol. 2003, 163, 935-946.
28. Jones, M.K.; Padilla, O.R.; Webb, N.A.; Norng, M. The anti-apoptosis protein, survivin, mediates gastric epithelial cell cytoprotection against ethanol-induced injury via activation of the p34 (CDC2) cyclin dependent kinase. J. Cell. Physiol. 2008, 215, 750-764.
29. Terasaki, Y.; Terasaki, M.; Urushiyama, H.; Nagasaka, S.; Takahashi, M.; Kunugi, S.; Ishikawa, A.; Wakamatsu, K.; Kuwahara, N.; Miyake, K., et al. Role of survivin in acute lung injury: Epithelial cells of mice and humans. Lab. Investig. 2013, 93, 1147-1163.
30. Chen, J.; Wu, W.; Tahir, S.K.; Kroeger, P.E.; Rosenberg, S.H.; Cowsert, L.M.; Bennett, F.; Krajewski, S.; Krajewska, M.; Welsh, K., et al. Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth. Neoplasia 2000, 2, 235-241.
31. Levkau, B.; Schäfers, M.; Wohlschlaeger, J.; von Wnuck Lipinski, K.; Keul, P.; Hermann, S.; Kawaguchi, N.; Kirchhof, P.; Fabritz, L.; Stypmann, J., et al. Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation 2008, 117, 1583-1593.
32. Pavenstadt, H.; Kriz W.; Kretzler M. Cell biology of the glomerular podocyte. Physiol. Rev. 2003, 83, 253-307.
33. Kriz, W. Podocyte is the major culprit accounting for the progression of chronic renal disease. Microsc. Res. Tech. 2002, 57, 189-195.
34. D'Agati, V.D. The spectrum of focal segmental glomerulosclerosis: New insights. Curr. Opin. Nephrol. Hypertens. 2008, 17, 271-281.
35. Pollak, M.R. Focal segmental glomerulosclerosis: Recent advances. Curr. Opin. Nephrol. Hypertens. 2008, 17, 138-142.
36. Miao, J.; Fan, Q.; Cui, Q.; Zhang, H.; Chen, L.; Wang, S.; Guan, N.; Guan, Y.; Ding, J. Newly identified cytoskeletal components are associated with dynamic changes of podocyte foot processes. Nephrol. Dial. Transplant. 2009, 24, 3297-3305.
37. Shiiki, H.; Sasaki, Y.; Nishino, T.; Kimura, T.; Kurioka, H.; Fujimoto, S.; Dohi, K. Cell proliferation and apoptosis of the glomerular epithelial cells in rats with puromycin aminonucleoside nephrosis. Pathobiology 1998, 66, 221-229.
38. Kim, Y.H.; Goyal, M.; Kurnit, D.; Wharram, B.; Wiggins, J.; Holzman, L.; Kershaw, D.; Wiggins, R. Podocyte depletion and glomerulosclerosis have a direct relationship in the PAN-treated rat. Kidney Int. 2002, 60, 957-968.
39. Zheng, C.X.; Chen, Z.H.; Zeng, C.H.; Qin, W.S.; Li, L.S.; Liu, Z.H. Triptolide protects podocytes from puromycin aminonucleoside induced injury in vivo and in vitro. Kidney Int. 2008, 74, 596-612.
40. Wada, T.; Pippin, J.W.; Marshall, C.B.; Griffin, S.V.; Shankland, S.J. Dexamethasone prevents podocyte apoptosis induced by puromycin aminonucleoside: Role of p53 and Bcl-2-related family proteins. J. Am. Soc. Nephrol. 2005, 16, 2615-2625.
41. Liu, S.F.; Ding, J.; Fan, Q.F.; Zhang, H. Establishment of a podocyte cell injury model induced by puromycin aminonucleoside. Beijing Da Xue Xue Bao 2008, 40, 586-589. (In Chinese)
42. Suzuki, T.; Takemura, H.; Noiri, E.; Nosaka, K.; Toda, A.; Taniguchi, S.; Uchida, K.; Fujita, T.; Kimura, S.; Nakao, A. Puromycin aminonucleoside induces apoptosis and increases HNE in cultured glomerular epithelial cells(1). Free Radic. Biol. Med. 2001, 31, 615-623.
43. Koshikawa, M.; Mukoyama, M.; Mori, K.; Suganami, T.; Sawai, K.; Yoshioka, T.; Nagae, T.; Yokoi, H.; Kawachi, H.; Shimizu, F., et al. Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome. J. Am. Soc. Nephrol. 2005, 16, 2690-2701.
44. Liu, S.; Shi, W.; Xiao, H.; Liang, X.; Deng, C.; Ye, Z.; Mei, P.; Wang, S.; Liu, X.; Shan, Z., et al. Receptor activator of NF-kappaB and podocytes: Towards a function of a novel receptor-ligand pair in the survival response of podocyte injury. PLoS One 2012, 7, e41331.
45. Ma, J.; Matsusaka, T.; Yang, H.C.; Zhong, J.; Takagi, N.; Fogo, A.B.; Kon, V.; Ichikawa, I. Induction of podocyte-derived VEGF ameliorates podocyte injury and subsequent abnormal glomerular development caused by puromycin aminonucleoside. Pediatr. Res. 2011, 70, 83-89.
46. Yu, S.Y.; Qi, R. Role of bad in podocyte apoptosis induced by puromycin aminonucleoside. Transplant. Proc. 2013, 45, 569-573.
47. Rincon, J.; Romero, M.; Viera, N.; Pedreañez, A.; Mosquera, J. Increased oxidative stress and apoptosis in acute puromycin aminonucleoside nephrosis. Int. J. Exp. Path. 2004, 85, 25-33.
48. George, J.; Banik, N.L.; Ray, S.K. Survivin knockdown and concurrent 4-HPR treatment controlled human glioblastoma in vitro and in vivo. Neuro Oncol. 2010, 12, 1088-1101.
49. Watanabe, A.; Taniguchi, F.; Izawa, M.; Suou, K.; Uegaki, T.; Takai, E.; Terakawa, N. The role of survivin in the resistance of endometriotic stromal cells to drug-induced apoptosis. Hum. Reprod. 2009, 24, 3172-3179.
50. Chen, J.; Chen, J.K.; Conway, E.M.; Harris, R.C. Survivin mediates renal proximal tubule recovery from AKI. J. Am. Soc. Nephrol. 2013, 24, 2023-2033.
51. Altieri, D.C. Targeting survivin in cancer. Cancer Lett. 2013, 332, 225-228.
52. Croci, D.O.; Cogno, I.S.; Vittar, N.B.; Salvatierra, E.; Trajtenberg, F.; Podhajcer, O.; Osinaga, E.; Rabinovich, G.A.; Rivarola, V.A. Silencing survivin gene expression promotes apoptosis of human breast cancer cells through a caspase independent pathway. J. Cell. Biochem. 2008, 105, 381-390.
53. Cheung, C.H.; Chen, H.H.; Kuo, C.C.; Chang, C.Y.; Coumar, M.S.; Hsieh, H.P.; Chang, J.Y. Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers. Mol. Cancer 2009, 8, 1-15.
54. Shimo, T.; Adachi, Y.; Yamanouchi, S.; Tsuji, S.; Kimata, T.; Umezawa, K.; Okigaki, M.; Takaya, J.; Ikehara, S.; Kaneko, K. A novel nuclear factor κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates puromycin aminonucleoside-induced nephrosis in mice. Am. J. Nephrol. 2013, 37, 302-309.
55. Eto, N.; Wada, T.; Inagi, R.; Takano, H.; Shimizu, A.; Kato, H.; Kurihara, H.; Kawachi, H.; Shankland, S.J.; Fujita, T., et al. Podocyte protection by darbepoetin: Preservation of the cytoskeleton and nephrin expression. Kidney Int. 2007, 72, 455-463.