-
1
-
-
0028834520
-
Increasing incidence of focal-segmental glomerulosclerosis among adult nephropathies: A 20-year renal biopsy study
-
Haas M, Spargo BH, Coventry S. Increasing incidence of focal-segmental glomerulosclerosis among adult nephropathies: a 20-year renal biopsy study. Am J Kidney Dis 1995; 26:740-750.
-
(1995)
Am J Kidney Dis
, vol.26
, pp. 740-750
-
-
Haas, M.1
Spargo, B.H.2
Coventry, S.3
-
2
-
-
0024998192
-
Focal sclerosing glomerulonephritis in a child with Laurence-Moon-Biedl syndrome
-
Barakat AJ, Arianas P, GlickAD, et al. Focal sclerosing glomerulonephritis in a child with Laurence-Moon-Biedl syndrome. Child Nephrol Urol 1990; 10:109-111.
-
(1990)
Child Nephrol Urol
, vol.10
, pp. 109-111
-
-
Barakat, A.J.1
Arianas, P.2
GlickAD3
-
3
-
-
0021153764
-
Nephropathy associated with Charcot-Marie-Tooth disease
-
Hara M, Ichida F, Higuchi A, et al. Nephropathy associated with Charcot-Marie-Tooth disease. Int J Pediatr Nephrol 1984; 5:99-102.
-
(1984)
Int J Pediatr Nephrol
, vol.5
, pp. 99-102
-
-
Hara, M.1
Ichida, F.2
Higuchi, A.3
-
4
-
-
34548496884
-
Resolved: Capillary endothelium is a major contributor to the glomerular filtration barrier
-
Ballermann BJ, Stan RV. Resolved: capillary endothelium is a major contributor to the glomerular filtration barrier. J Am Soc Nephrol 2007; 18:2432-2438.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 2432-2438
-
-
Ballermann, B.J.1
Stan, R.V.2
-
5
-
-
0034004155
-
Cell cycle regulatory proteins in renal disease: Role in hypertrophy, proliferation, and apoptosis
-
Shankland SJ, Wolf G. Cell cycle regulatory proteins in renal disease: role in hypertrophy, proliferation, and apoptosis. Am J Physiol Renal Physiol 2000; 278:F515-F529.
-
(2000)
Am J Physiol Renal Physiol
, vol.278
-
-
Shankland, S.J.1
Wolf, G.2
-
6
-
-
33745058119
-
The podocyte's response to injury: Role in proteinuria and glomerulosclerosis
-
Shankland SJ. The podocyte's response to injury: role in proteinuria and glomerulosclerosis. Kidney Int 2006; 69:2131-2147.
-
(2006)
Kidney Int
, vol.69
, pp. 2131-2147
-
-
Shankland, S.J.1
-
7
-
-
0032015551
-
Positionally cloned gene for a novel glomerular protein - Nephrin is mutated in congenital nephrotic syndrome
-
Kestila M, Lenkkeri U, Mannikko M, et al. Positionally cloned gene for a novel glomerular protein - Nephrin is mutated in congenital nephrotic syndrome. Mol Cell 1998; 1:575-582.
-
(1998)
Mol Cell
, vol.1
, pp. 575-582
-
-
Kestila, M.1
Lenkkeri, U.2
Mannikko, M.3
-
8
-
-
0034034757
-
NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome
-
Boute N, Gribouval O, Roselli S, et al. NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome. Nat Genet 2000; 24:349-354.
-
(2000)
Nat Genet
, vol.24
, pp. 349-354
-
-
Boute, N.1
Gribouval, O.2
Roselli, S.3
-
9
-
-
0034948819
-
Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN
-
Donoviel DB, Freed DD, Vogel H, et al. Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN. Mol Cell Biol 2001; 21:4829-4836.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4829-4836
-
-
Donoviel, D.B.1
Freed, D.D.2
Vogel, H.3
-
10
-
-
33646401549
-
Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization
-
Verma R, Kovari I, Soofi A, et al. Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization. J Clin Invest 2006; 116:1346-1359.
-
(2006)
J Clin Invest
, vol.116
, pp. 1346-1359
-
-
Verma, R.1
Kovari, I.2
Soofi, A.3
-
11
-
-
33645746950
-
Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes
-
Jones N, Blasutig IM, Eremina V, et al. Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes. Nature 2006; 440:818-823.
-
(2006)
Nature
, vol.440
, pp. 818-823
-
-
Jones, N.1
Blasutig, I.M.2
Eremina, V.3
-
12
-
-
37549036286
-
Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization
-
Garg P, Verma R, Nihalani D, et al. Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization. Mol Cell Biol 2007; 27:8698-8712.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 8698-8712
-
-
Garg, P.1
Verma, R.2
Nihalani, D.3
-
13
-
-
20844461826
-
A mutation in theTRPC6 cation channel • causes familial focal segmental glomerulosclerosis
-
Winn MP, Conlon PJ, Lynn KL, et al. A mutation in theTRPC6 cation channel • causes familial focal segmental glomerulosclerosis. Science 2005; 308: 1801-1804.
-
(2005)
Science
, vol.308
, pp. 1801-1804
-
-
Winn, M.P.1
Conlon, P.J.2
Lynn, K.L.3
-
14
-
-
38049032013
-
Modification of kidney barrier function by • the urokinase receptor
-
This study showed that upregulation of the urokinase receptor results in proteinuria and podocyte effacement through activation of αvβ3 integrin. Blockade of the αvβ3 integrin by specific inhibitors reduced proteinuria
-
Wei C, Moller CC, Altintas MM, et al. Modification of kidney barrier function by • the urokinase receptor. Nat Med 2008; 14:55-63. This study showed that upregulation of the urokinase receptor results in proteinuria and podocyte effacement through activation of αvβ3 integrin. Blockade of the αvβ3 integrin by specific inhibitors reduced proteinuria.
-
(2008)
Nat Med
, vol.14
, pp. 55-63
-
-
Wei, C.1
Moller, C.C.2
Altintas, M.M.3
-
15
-
-
34548324281
-
Synaptopodin protects against proteinuria by disrupting Cdc42:IRSp53:Mena signaling complexes in kidney podocytes
-
Yanagida-Asanuma E, Asanuma K, Kim K, et al. Synaptopodin protects against proteinuria by disrupting Cdc42:IRSp53:Mena signaling complexes in kidney podocytes. Am J Pathol 2007; 171:415-427.
-
(2007)
Am J Pathol
, vol.171
, pp. 415-427
-
-
Yanagida-Asanuma, E.1
Asanuma, K.2
Kim, K.3
-
16
-
-
34547654202
-
Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease
-
SeverS, Altintas MM, Nankoe SR, et al. Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease. J Clin Invest 2007; 117:2095-2104.
-
(2007)
J Clin Invest
, vol.117
, pp. 2095-2104
-
-
Sever, S.1
Altintas, M.M.2
Nankoe, S.R.3
-
17
-
-
34249874096
-
Mutation in the key enzyme of sialic acid biosynthesis causes severe glomerular proteinuria and is rescued by N-acetylmannosamine
-
GaleanoB, KlootwijkR, Manoli I, et al. Mutation in the key enzyme of sialic acid biosynthesis causes severe glomerular proteinuria and is rescued by N-acetylmannosamine. J Clin Invest 2007; 117:1585-1594.
-
(2007)
J Clin Invest
, vol.117
, pp. 1585-1594
-
-
Galeano, B.1
Klootwijk, R.2
Manoli, I.3
-
18
-
-
33751531864
-
Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible
-
Hinkes B, Wiggins RC, Gbadegesin R, et al. Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible. Nat Genet 2006; 38:1397-1405.
-
(2006)
Nat Genet
, vol.38
, pp. 1397-1405
-
-
Hinkes, B.1
Wiggins, R.C.2
Gbadegesin, R.3
-
19
-
-
34447118146
-
Slit diaphragm junctional complex and regulation of the cytoskeleton
-
Garg P, Verma R, Holzman LB. Slit diaphragm junctional complex and regulation of the cytoskeleton. Nephron Exp Nephrol 2007; 106:e67-e72.
-
(2007)
Nephron Exp Nephrol
, vol.106
-
-
Garg, P.1
Verma, R.2
Holzman, L.B.3
-
21
-
-
33646406847
-
Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin
-
Huber TB, Kwoh C, Wu H, et al. Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin. J Clin Invest 2006; 116:1337-1345.
-
(2006)
J Clin Invest
, vol.116
, pp. 1337-1345
-
-
Huber, T.B.1
Kwoh, C.2
Wu, H.3
-
22
-
-
22844436647
-
TRPC6 is a glomerular slit diaphragmassociated channel required for normal renal function
-
Reiser J, Polu KR, Moller CC, et al. TRPC6 is a glomerular slit diaphragmassociated channel required for normal renal function. Nat Genet 2005; 37:739-744.
-
(2005)
Nat Genet
, vol.37
, pp. 739-744
-
-
Reiser, J.1
Polu, K.R.2
Moller, C.C.3
-
23
-
-
33846028228
-
Induction of TRPC6 channel in acquired forms of proteinuric kidney disease
-
Moller CC, Wei C, Altintas MM, et al. Induction of TRPC6 channel in acquired forms of proteinuric kidney disease. J Am Soc Nephrol 2007; 18:29-36.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 29-36
-
-
Moller, C.C.1
Wei, C.2
Altintas, M.M.3
-
24
-
-
33744969296
-
Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signaling
-
Asanuma K, Yanagida-Asanuma E, Faul C, et al. Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signaling. Nat Cell Biol 2006; 8:485-491.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 485-491
-
-
Asanuma, K.1
Yanagida-Asanuma, E.2
Faul, C.3
-
25
-
-
0026729987
-
The altered glomerularfiltration slits seen in puromycin aminonucleoside nephrosis and protamine sulfate-treated rats contain the tight junction protein ZO-1.Am
-
KuriharaH, Anderson JM,KerjaschkiD, et al. The altered glomerularfiltration slits seen in puromycin aminonucleoside nephrosis and protamine sulfate-treated rats contain the tight junction protein ZO-1.Am J Pathol 1992; 141:805-816.
-
(1992)
J Pathol
, vol.141
, pp. 805-816
-
-
Kurihara, H.1
Anderson, J.M.2
Kerjaschki, D.3
-
26
-
-
3543098648
-
Podocyte flattening and disorder of glomerular basement membrane are associated with splitting of dystroglycanmatrix interaction
-
KojimaK, Davidovits A, Poczewski H, et al. Podocyte flattening and disorder of glomerular basement membrane are associated with splitting of dystroglycanmatrix interaction. J Am Soc Nephrol 2004; 15:2079-2089.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2079-2089
-
-
Kojima, K.1
Davidovits, A.2
Poczewski, H.3
-
27
-
-
12444302841
-
Podocytes that detach in experimental membranous nephropathy are viable
-
Petermann AT, Krofft R, Blonski M, et al. Podocytes that detach in experimental membranous nephropathy are viable. Kidney Int 2003; 64:1222-1231.
-
(2003)
Kidney Int
, vol.64
, pp. 1222-1231
-
-
Petermann, A.T.1
Krofft, R.2
Blonski, M.3
-
28
-
-
11244258291
-
Viable podocytes detach in experimental diabetic nephropathy: Potential mechanism underlying glomerulosclerosis
-
Petermann AT, Pippin J, Krofft R, et al. Viable podocytes detach in experimental diabetic nephropathy: potential mechanism underlying glomerulosclerosis. Nephron Exp Nephrol 2004; 98:e114-e123.
-
(2004)
Nephron Exp Nephrol
, vol.98
-
-
Petermann, A.T.1
Pippin, J.2
Krofft, R.3
-
30
-
-
34250000572
-
Urinary detection of podocyte injury
-
Camici M. Urinary detection of podocyte injury. Biomed Pharmacother 2007; 61:245-249.
-
(2007)
Biomed Pharmacother
, vol.61
, pp. 245-249
-
-
Camici, M.1
-
31
-
-
0035720564
-
Podocyte depletion and glomerulosclerosis have a direct relationship in the PAN-treated rat
-
Kim YH, Goyal M, Kurnit D, et al. Podocyte depletion and glomerulosclerosis have a direct relationship in the PAN-treated rat. Kidney Int 2001; 60:957-968.
-
(2001)
Kidney Int
, vol.60
, pp. 957-968
-
-
Kim, Y.H.1
Goyal, M.2
Kurnit, D.3
-
32
-
-
33748770599
-
Cyclin I protects podocytes from apoptosis
-
Griffin SV, Olivier JP, Pippin JW, et al. Cyclin I protects podocytes from apoptosis. J Biol Chem 2006; 281:28048-28057.
-
(2006)
J Biol Chem
, vol.281
, pp. 28048-28057
-
-
Griffin, S.V.1
Olivier, J.P.2
Pippin, J.W.3
-
33
-
-
33644801094
-
Dexamethasone prevents podocyte apoptosis induced by puromycin aminonucleoside: Role of p53 and Bcl-2-related family proteins
-
Wada T, Pippin JW, Marshall CB, et al. Dexamethasone prevents podocyte apoptosis induced by puromycin aminonucleoside: Role of p53 and Bcl-2-related family proteins. J Am Soc Nephrol 2005; 16:2615-2625.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2615-2625
-
-
Wada, T.1
Pippin, J.W.2
Marshall, C.B.3
-
34
-
-
18744366664
-
Glomerular localization of erythropoietin receptor mRNA and protein in neonatal and mature mouse kidney
-
Echigoya MH, Obikane K, Nakashima T, et al. Glomerular localization of erythropoietin receptor mRNA and protein in neonatal and mature mouse kidney. Nephron Exp Nephrol 2005; 100:e21-e29.
-
(2005)
Nephron Exp Nephrol
, vol.100
-
-
Echigoya, M.H.1
Obikane, K.2
Nakashima, T.3
-
35
-
-
34547746055
-
Darbepoetin alfa protects podocytes from apoptosis in vitro and in vivo
-
Logar CM, Brinkkoetter PT, Krofft RD, et al. Darbepoetin alfa protects podocytes from apoptosis in vitro and in vivo. Kidney Int 2007; 72:489-498.
-
(2007)
Kidney Int
, vol.72
, pp. 489-498
-
-
Logar, C.M.1
Brinkkoetter, P.T.2
Krofft, R.D.3
-
36
-
-
0041382617
-
Podocyte proliferation and differentiation in glomerular disease: Role of cell-cycle regulatory proteins
-
Griffin SV, Petermann AT, Durvasula RV, et al. Podocyte proliferation and differentiation in glomerular disease: role of cell-cycle regulatory proteins. Nephrol Dial Transplant 2003; 18 (Suppl 6):vi8-vi13.
-
(2003)
Nephrol Dial Transplant
, vol.18
, Issue.SUPPL. 6
-
-
Griffin, S.V.1
Petermann, A.T.2
Durvasula, R.V.3
-
37
-
-
1942506665
-
Reversal of collapsing glomerulopathy in mice with the cyclin-dependent kinase inhibitor CYC202
-
Gherardi D, D'Agati V, ChuTH, et al. Reversal of collapsing glomerulopathy in mice with the cyclin-dependent kinase inhibitor CYC202. J Am Soc Nephrol 2004; 15:1212-1222.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1212-1222
-
-
Gherardi, D.1
D'Agati, V.2
ChuTH3
-
38
-
-
20844451922
-
Limitation of podocyte proliferation improves renal function in experimental crescentic glomerulonephritis
-
Griffin SV, Krofft RD, Pippin JW, et al. Limitation of podocyte proliferation improves renal function in experimental crescentic glomerulonephritis. Kidney Int 2005; 67:977-986.
-
(2005)
Kidney Int
, vol.67
, pp. 977-986
-
-
Griffin, S.V.1
Krofft, R.D.2
Pippin, J.W.3
-
39
-
-
33645577151
-
Functional expression of the renin-angiotensin system in human podocytes
-
Liebau MC, Lang D,BohmJ,et al. Functional expression of the renin-angiotensin system in human podocytes. Am J Physiol Renal Physiol 2006; 290:F710-F719.
-
(2006)
Am J Physiol Renal Physiol
, vol.290
-
-
Liebau, M.C.1
Lang, D.2
Bohm, J.3
-
40
-
-
34548047701
-
Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytes
-
Velez JC, Bland AM, Arthur JM, et al. Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytes. Am J Physiol Renal Physiol 2007; 293:F398-F407.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
-
-
Velez, J.C.1
Bland, A.M.2
Arthur, J.M.3
-
41
-
-
33846666637
-
Angiotensin II type 1 receptor blockade inhibits the development and progression of HIV-associated nephropathy in a mouse model
-
Hiramatsu N, Hiromura K, Shigehara T, et al. Angiotensin II type 1 receptor blockade inhibits the development and progression of HIV-associated nephropathy in a mouse model. J Am Soc Nephrol 2007; 18:515-527.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 515-527
-
-
Hiramatsu, N.1
Hiromura, K.2
Shigehara, T.3
-
42
-
-
1642322962
-
The parietal epithelial cell: A key player in the pathogenesis of focal segmental glomerulosclerosis in Thy-1.1 transgenic mice
-
Smeets B, Te Loeke NA, Dijkman HB, et al. The parietal epithelial cell: a key player in the pathogenesis of focal segmental glomerulosclerosis in Thy-1.1 transgenic mice. J Am Soc Nephrol 2004; 15:928-939.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 928-939
-
-
Smeets, B.1
Te Loeke, N.A.2
Dijkman, H.B.3
-
43
-
-
33746730496
-
Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier
-
Jarad G, Cunningham J, Shaw AS, et al. Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier. J Clin Invest 2006; 116:2272-2279.
-
(2006)
J Clin Invest
, vol.116
, pp. 2272-2279
-
-
Jarad, G.1
Cunningham, J.2
Shaw, A.S.3
-
44
-
-
8444221929
-
Human laminin beta2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities
-
Zenker M, Aigner T, Wendler O, et al. Human laminin beta2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities. Hum Mol Genet 2004; 13:2625-2632.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 2625-2632
-
-
Zenker, M.1
Aigner, T.2
Wendler, O.3
-
45
-
-
0037389827
-
Why the kidney glomerulus does not clog: A gel permeation/ diffusion hypothesis of renal function
-
Smithies O. Why the kidney glomerulus does not clog: a gel permeation/ diffusion hypothesis of renal function. Proc Natl Acad Sci USA 2003; 100: 4108-4113.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4108-4113
-
-
Smithies, O.1
-
47
-
-
33746508999
-
A classification of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura and related disorders
-
Besbas N, Karpman D, Landau D, et al. A classification of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura and related disorders. Kidney Int 2006; 70:423-431.
-
(2006)
Kidney Int
, vol.70
, pp. 423-431
-
-
Besbas, N.1
Karpman, D.2
Landau, D.3
-
48
-
-
35848935010
-
Interferon-beta reduces protenuria in experimental glomerulonephritis
-
Satchell SC, Buchatska O, Khan SB, et al. Interferon-beta reduces protenuria in experimental glomerulonephritis. J Am Soc Nephrol 2007; 18: 2875-2884.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 2875-2884
-
-
Satchell, S.C.1
Buchatska, O.2
Khan, S.B.3
|