-
1
-
-
84902008991
-
The multiple facets of drug resistance: One history, different approaches
-
24775603 4041145
-
Niero EL, Rocha-Sales B, Lauand C, Cortez BA, de Souza MM, Rezende-Teixeira P, et al. The multiple facets of drug resistance: one history, different approaches. J Exp Clin Cancer Res. 2014;33:37.
-
(2014)
J Exp Clin Cancer Res
, vol.33
, pp. 37
-
-
Niero, E.L.1
Rocha-Sales, B.2
Lauand, C.3
Cortez, B.A.4
De Souza, M.M.5
Rezende-Teixeira, P.6
-
2
-
-
84884535896
-
Cancer drug resistance: An evolving paradigm
-
24060863
-
Holohan C, Van Schaeybroeck S, Longley DB, Johnston PG. Cancer drug resistance: an evolving paradigm. Nat Rev Cancer. 2013;13(10):714-26.
-
(2013)
Nat Rev Cancer
, vol.13
, Issue.10
, pp. 714-726
-
-
Holohan, C.1
Van Schaeybroeck, S.2
Longley, D.B.3
Johnston, P.G.4
-
3
-
-
13044249156
-
A multidrug resistance transporter from human MCF-7 breast cancer cells
-
9861027 28101
-
Doyle LA, Yang W, Abruzzo LV, Krogmann T, Gao Y, Rishi AK, et al. A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci. 1998;95(26):15665-70.
-
(1998)
Proc Natl Acad Sci
, vol.95
, Issue.26
, pp. 15665-15670
-
-
Doyle, L.A.1
Yang, W.2
Abruzzo, L.V.3
Krogmann, T.4
Gao, Y.5
Rishi, A.K.6
-
4
-
-
0032895533
-
Molecular Cloning of cDNAs Which Are Highly Overexpressed in Mitoxantrone-resistant Cells Demonstration of Homology to ABC Transport Genes
-
9892175
-
Miyake K, Mickley L, Litman T, Zhan Z, Robey R, Cristensen B, et al. Molecular Cloning of cDNAs Which Are Highly Overexpressed in Mitoxantrone-resistant Cells Demonstration of Homology to ABC Transport Genes. Cancer Res. 1999;59(1):8-13.
-
(1999)
Cancer Res
, vol.59
, Issue.1
, pp. 8-13
-
-
Miyake, K.1
Mickley, L.2
Litman, T.3
Zhan, Z.4
Robey, R.5
Cristensen, B.6
-
5
-
-
0032404092
-
A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
-
9850061
-
Allikmets R, Schriml LM, Hutchinson A, Romano-Spica V, Dean M. A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Cancer Res. 1998;58(23):5337-9.
-
(1998)
Cancer Res
, vol.58
, Issue.23
, pp. 5337-5339
-
-
Allikmets, R.1
Schriml, L.M.2
Hutchinson, A.3
Romano-Spica, V.4
Dean, M.5
-
6
-
-
0037427379
-
Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood-brain barrier
-
12706238
-
Eisenblätter T, Hüwel S, Galla H-J. Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood-brain barrier. Brain Res. 2003;971(2):221-31.
-
(2003)
Brain Res
, vol.971
, Issue.2
, pp. 221-231
-
-
Eisenblätter, T.1
Hüwel, S.2
Galla, H.-J.3
-
7
-
-
23044472581
-
Distribution of breast cancer resistance protein (BCRP/ABCG2) mRNA expression along the human GI tract
-
15998509
-
Gutmann H, Hruz P, Zimmermann C, Beglinger C, Drewe J. Distribution of breast cancer resistance protein (BCRP/ABCG2) mRNA expression along the human GI tract. Biochem Pharmacol. 2005;70(5):695-9.
-
(2005)
Biochem Pharmacol
, vol.70
, Issue.5
, pp. 695-699
-
-
Gutmann, H.1
Hruz, P.2
Zimmermann, C.3
Beglinger, C.4
Drewe, J.5
-
8
-
-
14644409841
-
The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk
-
15685169
-
Jonker JW, Merino G, Musters S, van Herwaarden AE, Bolscher E, Wagenaar E, et al. The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk. Nat Med. 2005;11(2):127-9.
-
(2005)
Nat Med
, vol.11
, Issue.2
, pp. 127-129
-
-
Jonker, J.W.1
Merino, G.2
Musters, S.3
Van Herwaarden, A.E.4
Bolscher, E.5
Wagenaar, E.6
-
9
-
-
34247367926
-
Molecular and cellular characterization of ABCG2 in the prostate
-
17425799 1853103
-
Pascal LE, Oudes AJ, Petersen TW, Goo YA, Walashek LS, True LD, et al. Molecular and cellular characterization of ABCG2 in the prostate. BMC Urol. 2007;7(1):6.
-
(2007)
BMC Urol
, vol.7
, Issue.1
, pp. 6
-
-
Pascal, L.E.1
Oudes, A.J.2
Petersen, T.W.3
Goo, Y.A.4
Walashek, L.S.5
True, L.D.6
-
10
-
-
33645930969
-
Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues
-
15990223
-
Fetsch PA, Abati A, Litman T, Morisaki K, Honjo Y, Mittal K, et al. Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues. Cancer Lett. 2006;235(1):84-92.
-
(2006)
Cancer Lett
, vol.235
, Issue.1
, pp. 84-92
-
-
Fetsch, P.A.1
Abati, A.2
Litman, T.3
Morisaki, K.4
Honjo, Y.5
Mittal, K.6
-
11
-
-
10744232004
-
Reversal of breast cancer resistance protein (BCRP/ABCG2)-mediated drug resistance by novobiocin, a coumermycin antibiotic
-
14618629
-
Shiozawa K, Oka M, Soda H, Yoshikawa M, Ikegami Y, Tsurutani J, et al. Reversal of breast cancer resistance protein (BCRP/ABCG2)-mediated drug resistance by novobiocin, a coumermycin antibiotic. Int J Cancer. 2004;108(1):146-51.
-
(2004)
Int J Cancer
, vol.108
, Issue.1
, pp. 146-151
-
-
Shiozawa, K.1
Oka, M.2
Soda, H.3
Yoshikawa, M.4
Ikegami, Y.5
Tsurutani, J.6
-
12
-
-
0037444271
-
Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoprotein
-
12649196
-
Allen JD, Van Dort SC, Buitelaar M, van Tellingen O, Schinkel AH. Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoprotein. Cancer Res. 2003;63(6):1339-44.
-
(2003)
Cancer Res
, vol.63
, Issue.6
, pp. 1339-1344
-
-
Allen, J.D.1
Van Dort, S.C.2
Buitelaar, M.3
Van Tellingen, O.4
Schinkel, A.H.5
-
13
-
-
16844384057
-
The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): Implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients
-
15805252
-
Breedveld P, Pluim D, Cipriani G, Wielinga P, van Tellingen O, Schinkel AH, et al. The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients. Cancer Res. 2005;65(7):2577-82.
-
(2005)
Cancer Res
, vol.65
, Issue.7
, pp. 2577-2582
-
-
Breedveld, P.1
Pluim, D.2
Cipriani, G.3
Wielinga, P.4
Van Tellingen, O.5
Schinkel, A.H.6
-
14
-
-
70350132811
-
Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: Implications for altered anti-cancer effects and pharmacological properties
-
19785662 2785536
-
Hegedus C, Özvegy-Laczka C, Apati A, Magocsi M, Nemet K, Orfi L, et al. Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties. Br J Pharmacol. 2009;158(4):1153-64.
-
(2009)
Br J Pharmacol
, vol.158
, Issue.4
, pp. 1153-1164
-
-
Hegedus, C.1
Özvegy-Laczka, C.2
Apati, A.3
Magocsi, M.4
Nemet, K.5
Orfi, L.6
-
15
-
-
20144389530
-
Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib)
-
15753373
-
Elkind NB, Szentpétery Z, Apáti Á, Özvegy-Laczka C, Várady G, Ujhelly O, et al. Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib). Cancer Res. 2005;65(5):1770-7.
-
(2005)
Cancer Res
, vol.65
, Issue.5
, pp. 1770-1777
-
-
Elkind, N.B.1
Szentpétery, Z.2
Apáti, Á.3
Özvegy-Laczka, C.4
Várady, G.5
Ujhelly, O.6
-
16
-
-
53349099403
-
Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1-/-/Mdr1a/1b-/-(triple-knockout) and wild-type mice
-
18723475
-
Marchetti S, de Vries NA, Buckle T, Bolijn MJ, van Eijndhoven MA, Beijnen JH, et al. Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1-/-/Mdr1a/1b-/-(triple-knockout) and wild-type mice. Mol Cancer Ther. 2008;7(8):2280-7.
-
(2008)
Mol Cancer Ther
, vol.7
, Issue.8
, pp. 2280-2287
-
-
Marchetti, S.1
De Vries, N.A.2
Buckle, T.3
Bolijn, M.J.4
Van Eijndhoven, M.A.5
Beijnen, J.H.6
-
17
-
-
84885972386
-
Molecular pharmacology of ABCG2 and its role in chemoresistance
-
24021215
-
Stacy AE, Jansson PJ, Richardson DR. Molecular pharmacology of ABCG2 and its role in chemoresistance. Mol Pharmacol. 2013;84(5):655-69.
-
(2013)
Mol Pharmacol
, vol.84
, Issue.5
, pp. 655-669
-
-
Stacy, A.E.1
Jansson, P.J.2
Richardson, D.R.3
-
18
-
-
33947381412
-
ABCG2: Determining its relevance in clinical drug resistance
-
17323127
-
Robey RW, Polgar O, Deeken J, To KW, Bates SE. ABCG2: determining its relevance in clinical drug resistance. Cancer Metastasis Rev. 2007;26(1):39-57.
-
(2007)
Cancer Metastasis Rev
, vol.26
, Issue.1
, pp. 39-57
-
-
Robey, R.W.1
Polgar, O.2
Deeken, J.3
To, K.W.4
Bates, S.E.5
-
20
-
-
84859727401
-
Human ABCG2: Structure, function, and its role in multidrug resistance
-
22509477 3325772
-
Mo W, Zhang J-T. Human ABCG2: structure, function, and its role in multidrug resistance. Int J Biochem Mol Biol. 2012;3(1):1-27.
-
(2012)
Int J Biochem Mol Biol
, vol.3
, Issue.1
, pp. 1-27
-
-
Mo, W.1
Zhang, J.-T.2
-
21
-
-
0035834595
-
Transport of 7-ethyl-10-hydroxycamptothecin (SN-38) by breast cancer resistance protein ABCG2 in human lung cancer cells
-
11688982
-
Nakatomi K, Yoshikawa M, Oka M, Ikegami Y, Hayasaka S, Sano K, et al. Transport of 7-ethyl-10-hydroxycamptothecin (SN-38) by breast cancer resistance protein ABCG2 in human lung cancer cells. Biochem Biophys Res Commun. 2001;288(4):827-32.
-
(2001)
Biochem Biophys Res Commun
, vol.288
, Issue.4
, pp. 827-832
-
-
Nakatomi, K.1
Yoshikawa, M.2
Oka, M.3
Ikegami, Y.4
Hayasaka, S.5
Sano, K.6
-
22
-
-
18744421466
-
Breast cancer resistance protein is localized at the plasma membrane in mitoxantrone-and topotecan-resistant cell lines
-
10825126
-
Scheffer GL, Maliepaard M, Pijnenborg AC, van Gastelen MA, de Jong MC, Schroeijers AB, et al. Breast cancer resistance protein is localized at the plasma membrane in mitoxantrone-and topotecan-resistant cell lines. Cancer Res. 2000;60(10):2589-93.
-
(2000)
Cancer Res
, vol.60
, Issue.10
, pp. 2589-2593
-
-
Scheffer, G.L.1
Maliepaard, M.2
Pijnenborg, A.C.3
Van Gastelen, M.A.4
De Jong, M.C.5
Schroeijers, A.B.6
-
23
-
-
0345688604
-
Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)
-
14576842
-
Doyle LA, Ross DD. Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2). Oncogene. 2003;22(47):7340-58.
-
(2003)
Oncogene
, vol.22
, Issue.47
, pp. 7340-7358
-
-
Doyle, L.A.1
Ross, D.D.2
-
24
-
-
0141815941
-
Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter
-
14500392
-
Volk EL, Schneider E. Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter. Cancer Res. 2003;63(17):5538-43.
-
(2003)
Cancer Res
, vol.63
, Issue.17
, pp. 5538-5543
-
-
Volk, E.L.1
Schneider, E.2
-
25
-
-
0035138482
-
Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells
-
11205902
-
Robey RW, Medina-Pérez WY, Nishiyama K, Lahusen T, Miyake K, Litman T, et al. Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells. Clin Cancer Res. 2001;7(1):145-52.
-
(2001)
Clin Cancer Res
, vol.7
, Issue.1
, pp. 145-152
-
-
Robey, R.W.1
Medina-Pérez, W.Y.2
Nishiyama, K.3
Lahusen, T.4
Miyake, K.5
Litman, T.6
-
26
-
-
84863341371
-
Effect of 5-FU and MTX on the expression of drug-resistance related cancer stem cell markers in non-small cell lung cancer cells
-
22416214 3298820
-
Yi H, Cho H-J, Cho S-M, Jo K, Park J-A, Lee S-H, et al. Effect of 5-FU and MTX on the expression of drug-resistance related cancer stem cell markers in non-small cell lung cancer cells. Korean J Physiol Pharmacol. 2012;16(1):11-6.
-
(2012)
Korean J Physiol Pharmacol
, vol.16
, Issue.1
, pp. 11-16
-
-
Yi, H.1
Cho, H.-J.2
Cho, S.-M.3
Jo, K.4
Park, J.-A.5
Lee, S.-H.6
-
27
-
-
0034906472
-
Circumvention of breast cancer resistance protein (BCRP)-mediated resistance to camptothecins in vitro using non-substrate drugs or the BCRP inhibitor GF120918
-
11309344
-
Maliepaard M, van Gastelen MA, Tohgo A, Hausheer FH, van Waardenburg RC, de Jong LA, et al. Circumvention of breast cancer resistance protein (BCRP)-mediated resistance to camptothecins in vitro using non-substrate drugs or the BCRP inhibitor GF120918. Clin Cancer Res. 2001;7(4):935-41.
-
(2001)
Clin Cancer Res
, vol.7
, Issue.4
, pp. 935-941
-
-
Maliepaard, M.1
Van Gastelen, M.A.2
Tohgo, A.3
Hausheer, F.H.4
Van Waardenburg, R.C.5
De Jong, L.A.6
-
28
-
-
54049137262
-
Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides
-
18765824
-
de Wolf C, Jansen R, Yamaguchi H, de Haas M, van de Wetering K, Wijnholds J, et al. Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides. Mol Cancer Ther. 2008;7(9):3092-102.
-
(2008)
Mol Cancer Ther
, vol.7
, Issue.9
, pp. 3092-3102
-
-
De Wolf, C.1
Jansen, R.2
Yamaguchi, H.3
De Haas, M.4
Van De Wetering, K.5
Wijnholds, J.6
-
29
-
-
12844255054
-
Single amino acid (482) variants of the ABCG2 multidrug transporter: Major differences in transport capacity and substrate recognition
-
Özvegy-Laczka C, Köblös G, Sarkadi B, Váradi A. Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition. Biochim Biophys Acta Biomembr. 2005;1668(1):53-63.
-
(2005)
Biochim Biophys Acta Biomembr
, vol.1668
, Issue.1
, pp. 53-63
-
-
Özvegy-Laczka, C.1
Köblös, G.2
Sarkadi, B.3
Váradi, A.4
-
30
-
-
0347382812
-
Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity
-
14612912 2394461
-
Robey R, Honjo Y, Morisaki K, Nadjem T, Runge S, Risbood M, et al. Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity. Br J Cancer. 2003;89(10):1971-8.
-
(2003)
Br J Cancer
, vol.89
, Issue.10
, pp. 1971-1978
-
-
Robey, R.1
Honjo, Y.2
Morisaki, K.3
Nadjem, T.4
Runge, S.5
Risbood, M.6
-
31
-
-
9744264044
-
Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias
-
15585622
-
Benderra Z, Faussat A-M, Sayada L, Perrot J-Y, Chaoui D, Marie J-P, et al. Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias. Clin Cancer Res. 2004;10(23):7896-902.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.23
, pp. 7896-7902
-
-
Benderra, Z.1
Faussat, A.-M.2
Sayada, L.3
Perrot, J.-Y.4
Chaoui, D.5
Marie, J.-P.6
-
32
-
-
27744562662
-
MRP3, BCRP, and P-glycoprotein activities are prognostic factors in adult acute myeloid leukemia
-
16278398
-
Benderra Z, Faussat AM, Sayada L, Perrot J-Y, Tang R, Chaoui D, et al. MRP3, BCRP, and P-glycoprotein activities are prognostic factors in adult acute myeloid leukemia. Clin Cancer Res. 2005;11(21):7764-72.
-
(2005)
Clin Cancer Res
, vol.11
, Issue.21
, pp. 7764-7772
-
-
Benderra, Z.1
Faussat, A.M.2
Sayada, L.3
Perrot, J.-Y.4
Tang, R.5
Chaoui, D.6
-
33
-
-
10644230985
-
BCRP mRNA expression v. Clinical outcome in 40 adult AML patients
-
15607361
-
Uggla B, Ståhl E, Wågsäter D, Paul C, Karlsson MG, Sirsjö A, et al. BCRP mRNA expression v. clinical outcome in 40 adult AML patients. Leuk Res. 2005;29(2):141-6.
-
(2005)
Leuk Res
, vol.29
, Issue.2
, pp. 141-146
-
-
Uggla, B.1
Ståhl, E.2
Wågsäter, D.3
Paul, C.4
Karlsson, M.G.5
Sirsjö, A.6
-
34
-
-
67349169090
-
Expression of breast cancer resistance protein is associated with a poor clinical outcome in patients with small-cell lung cancer
-
19036469
-
Kim YH, Ishii G, Goto K, Ota S, Kubota K, Murata Y, et al. Expression of breast cancer resistance protein is associated with a poor clinical outcome in patients with small-cell lung cancer. Lung Cancer. 2009;65(1):105-11.
-
(2009)
Lung Cancer
, vol.65
, Issue.1
, pp. 105-111
-
-
Kim, Y.H.1
Ishii, G.2
Goto, K.3
Ota, S.4
Kubota, K.5
Murata, Y.6
-
35
-
-
61449247252
-
Immunohistochemical expression of BCRP and ERCC1 in biopsy specimen predicts survival in advanced non-small-cell lung cancer treated with cisplatin-based chemotherapy
-
18823676
-
Ota S, Ishii G, Goto K, Kubota K, Kim YH, Kojika M, et al. Immunohistochemical expression of BCRP and ERCC1 in biopsy specimen predicts survival in advanced non-small-cell lung cancer treated with cisplatin-based chemotherapy. Lung Cancer. 2009;64(1):98-104.
-
(2009)
Lung Cancer
, vol.64
, Issue.1
, pp. 98-104
-
-
Ota, S.1
Ishii, G.2
Goto, K.3
Kubota, K.4
Kim, Y.H.5
Kojika, M.6
-
36
-
-
84943355596
-
OCT-1, ABCB1, and ABCG2 Expression in Imatinib-Resistant Chronic Myeloid Leukemia Treated with Dasatinib or Nilotinib
-
25568846 4276791
-
Kim Y-K, Lee S-S, Jeong S-H, Ahn J-S, Yang D-H, Lee J-J, et al. OCT-1, ABCB1, and ABCG2 Expression in Imatinib-Resistant Chronic Myeloid Leukemia Treated with Dasatinib or Nilotinib. Chonnam Med J. 2014;50(3):102-11.
-
(2014)
Chonnam Med J
, vol.50
, Issue.3
, pp. 102-111
-
-
Kim, Y.-K.1
Lee, S.-S.2
Jeong, S.-H.3
Ahn, J.-S.4
Yang, D.-H.5
Lee, J.-J.6
-
37
-
-
84952369377
-
Efficacy of PARP inhibitor rucaparib in orthotopic glioblastoma xenografts is limited by ineffective drug penetration into the central nervous system
-
Parrish KE, Cen L, Murray J, Calligaris D, Kizilbash S, Mittapalli RK, et al. Efficacy of PARP inhibitor rucaparib in orthotopic glioblastoma xenografts is limited by ineffective drug penetration into the central nervous system. Mol Cancer Ther. 2015;13(12):2735-43.
-
(2015)
Mol Cancer Ther
, vol.13
, Issue.12
, pp. 2735-2743
-
-
Parrish, K.E.1
Cen, L.2
Murray, J.3
Calligaris, D.4
Kizilbash, S.5
Mittapalli, R.K.6
-
38
-
-
84938587076
-
Breast Cancer Resistance Protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1) Restrict Oral Availability and Brain Accumulation of the PARP Inhibitor Rucaparib (AG-014699)
-
24962512
-
Durmus S, Sparidans RW, van Esch A, Wagenaar E, Beijnen JH, Schinkel AH. Breast Cancer Resistance Protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1) Restrict Oral Availability and Brain Accumulation of the PARP Inhibitor Rucaparib (AG-014699). Pharm Res. 2015;32(1):37-46.
-
(2015)
Pharm Res
, vol.32
, Issue.1
, pp. 37-46
-
-
Durmus, S.1
Sparidans, R.W.2
Van Esch, A.3
Wagenaar, E.4
Beijnen, J.H.5
Schinkel, A.H.6
-
39
-
-
1242293677
-
Pheophorbide a is a specific probe for ABCG2 function and inhibition
-
14973080
-
Robey RW, Steadman K, Polgar O, Morisaki K, Blayney M, Mistry P, et al. Pheophorbide a is a specific probe for ABCG2 function and inhibition. Cancer Res. 2004;64(4):1242-6.
-
(2004)
Cancer Res
, vol.64
, Issue.4
, pp. 1242-1246
-
-
Robey, R.W.1
Steadman, K.2
Polgar, O.3
Morisaki, K.4
Blayney, M.5
Mistry, P.6
-
40
-
-
84935426678
-
Enhanced efficacy of photodynamic therapy by inhibiting ABCG2 in colon cancers
-
26149077 4494642
-
Kim JH, Park JM, Roh YJ, Kim I-W, Hasan T, Choi M-G. Enhanced efficacy of photodynamic therapy by inhibiting ABCG2 in colon cancers. BMC Cancer. 2015;15(1):504.
-
(2015)
BMC Cancer
, vol.15
, Issue.1
, pp. 504
-
-
Kim, J.H.1
Park, J.M.2
Roh, Y.J.3
Kim, I.-W.4
Hasan, T.5
Choi, M.-G.6
-
41
-
-
25144491076
-
ABCG2-mediated transport of photosensitizers: Potential impact on photodynamic therapy
-
Robey RW, Steadman K, Polgar O, Bates SE. ABCG2-mediated transport of photosensitizers: potential impact on photodynamic therapy. Cancer Biol Ther. 2005;4(2):195-202.
-
(2005)
Cancer Biol Ther
, vol.4
, Issue.2
, pp. 195-202
-
-
Robey, R.W.1
Steadman, K.2
Polgar, O.3
Bates, S.E.4
-
42
-
-
34247886063
-
The tyrosine kinase inhibitor imatinib mesylate enhances the efficacy of photodynamic therapy by inhibiting ABCG2
-
17438106
-
Liu W, Baer MR, Bowman MJ, Pera P, Zheng X, Morgan J, et al. The tyrosine kinase inhibitor imatinib mesylate enhances the efficacy of photodynamic therapy by inhibiting ABCG2. Clin Cancer Res. 2007;13(8):2463-70.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.8
, pp. 2463-2470
-
-
Liu, W.1
Baer, M.R.2
Bowman, M.J.3
Pera, P.4
Zheng, X.5
Morgan, J.6
-
43
-
-
77957723627
-
Substrate affinity of photosensitizers derived from chlorophyll-a: The ABCG2 transporter affects the phototoxic response of side population stem cell-like cancer cells to photodynamic therapy
-
20684544 3017217
-
Morgan J, Jackson JD, Zheng X, Pandey SK, Pandey RK. Substrate affinity of photosensitizers derived from chlorophyll-a: the ABCG2 transporter affects the phototoxic response of side population stem cell-like cancer cells to photodynamic therapy. Mol Pharm. 2010;7(5):1789-804.
-
(2010)
Mol Pharm
, vol.7
, Issue.5
, pp. 1789-1804
-
-
Morgan, J.1
Jackson, J.D.2
Zheng, X.3
Pandey, S.K.4
Pandey, R.K.5
-
44
-
-
33645986455
-
Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: A randomised controlled multicentre phase III trial
-
16648043
-
Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen H-J, et al. Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol. 2006;7(5):392-401.
-
(2006)
Lancet Oncol
, vol.7
, Issue.5
, pp. 392-401
-
-
Stummer, W.1
Pichlmeier, U.2
Meinel, T.3
Wiestler, O.D.4
Zanella, F.5
Reulen, H.-J.6
-
45
-
-
0030989679
-
Photodynamic therapy of actinic keratosis with topical 5-aminolevulinic acid: A pilot dose-ranging study
-
9197826
-
Jeffes EW, McCullough JL, Weinstein GD, Fergin PE, Nelson JS, Shull TF, et al. Photodynamic therapy of actinic keratosis with topical 5-aminolevulinic acid: a pilot dose-ranging study. Arch Dermatol. 1997;133(6):727-32.
-
(1997)
Arch Dermatol
, vol.133
, Issue.6
, pp. 727-732
-
-
Jeffes, E.W.1
McCullough, J.L.2
Weinstein, G.D.3
Fergin, P.E.4
Nelson, J.S.5
Shull, T.F.6
-
46
-
-
9144225389
-
Photodynamic Therapy with Aminolevulinic Acid Topical Solution andVisible Blue Light in the Treatment of Multiple Actinic Keratoses of the Faceand Scalp: Investigator-Blinded, Phase 3, Multicenter Trials
-
14732659
-
Piacquadio DJ, Chen DM, Farber HF, Fowler Jr JF, Glazer SD, Goodman JJ, et al. Photodynamic Therapy With Aminolevulinic Acid Topical Solution andVisible Blue Light in the Treatment of Multiple Actinic Keratoses of the Faceand Scalp: Investigator-Blinded, Phase 3, Multicenter Trials. Arch Dermatol. 2004;140(1):41-6.
-
(2004)
Arch Dermatol
, vol.140
, Issue.1
, pp. 41-46
-
-
Piacquadio, D.J.1
Chen, D.M.2
Farber, H.F.3
Fowler, J.F.4
Glazer, S.D.5
Goodman, J.J.6
-
47
-
-
84885202666
-
Differential sensitivity in cell lines to photodynamic therapy in combination with ABCG2 inhibition
-
Barron GA, Moseley H, Woods JA. Differential sensitivity in cell lines to photodynamic therapy in combination with ABCG2 inhibition. J Photochem Photobiol B Biol. 2013;126:87-96.
-
(2013)
J Photochem Photobiol B Biol
, vol.126
, pp. 87-96
-
-
Barron, G.A.1
Moseley, H.2
Woods, J.A.3
-
48
-
-
84865966559
-
Pivotal roles of peptide transporter PEPT1 and ATP-binding cassette (ABC) transporter ABCG2 in 5-aminolevulinic acid (ALA)-based photocytotoxicity of gastric cancer cells in vitro
-
Hagiya Y, Endo Y, Yonemura Y, Takahashi K, Ishizuka M, Abe F, et al. Pivotal roles of peptide transporter PEPT1 and ATP-binding cassette (ABC) transporter ABCG2 in 5-aminolevulinic acid (ALA)-based photocytotoxicity of gastric cancer cells in vitro. Photodiagn Photodyn Ther. 2012;9(3):204-14.
-
(2012)
Photodiagn Photodyn Ther
, vol.9
, Issue.3
, pp. 204-214
-
-
Hagiya, Y.1
Endo, Y.2
Yonemura, Y.3
Takahashi, K.4
Ishizuka, M.5
Abe, F.6
-
49
-
-
72449131829
-
Breast cancer resistant protein (BCRP) is a molecular determinant of the outcome of photodynamic therapy (PDT) for centrally located early lung cancer
-
19477032
-
Usuda J, Tsunoda Y, Ichinose S, Ishizumi T, Ohtani K, Maehara S, et al. Breast cancer resistant protein (BCRP) is a molecular determinant of the outcome of photodynamic therapy (PDT) for centrally located early lung cancer. Lung Cancer. 2010;67(2):198-204.
-
(2010)
Lung Cancer
, vol.67
, Issue.2
, pp. 198-204
-
-
Usuda, J.1
Tsunoda, Y.2
Ichinose, S.3
Ishizumi, T.4
Ohtani, K.5
Maehara, S.6
-
50
-
-
52549087785
-
Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
-
18784658
-
Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer. 2008;8(10):755-68.
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.10
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
51
-
-
84880911745
-
Emerging role of cancer stem cells in the biology and treatment of ovarian cancer: Basic knowledge and therapeutic possibilities for an innovative approach
-
23902592 3734167
-
Tomao F, Papa A, Rossi L, Strudel M, Vici P, Lo Russo G, et al. Emerging role of cancer stem cells in the biology and treatment of ovarian cancer: basic knowledge and therapeutic possibilities for an innovative approach. J Exp Clin Cancer Res. 2013;32:48.
-
(2013)
J Exp Clin Cancer Res
, vol.32
, pp. 48
-
-
Tomao, F.1
Papa, A.2
Rossi, L.3
Strudel, M.4
Vici, P.5
Lo Russo, G.6
-
52
-
-
84866491082
-
Cancer stem cells
-
22981632 3496019
-
Yu Z, Pestell TG, Lisanti MP, Pestell RG. Cancer stem cells. Int J Biochem Cell Biol. 2012;44(12):2144-51.
-
(2012)
Int J Biochem Cell Biol
, vol.44
, Issue.12
, pp. 2144-2151
-
-
Yu, Z.1
Pestell, T.G.2
Lisanti, M.P.3
Pestell, R.G.4
-
53
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
7509044
-
Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Caceres-Cortes J, et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature. 1994;367(6464):645-8.
-
(1994)
Nature
, vol.367
, Issue.6464
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
Caceres-Cortes, J.6
-
54
-
-
0033529756
-
Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity
-
10430905 17742
-
Storms RW, Trujillo AP, Springer JB, Shah L, Colvin OM, Ludeman SM, et al. Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity. Proc Natl Acad Sci. 1999;96(16):9118-23.
-
(1999)
Proc Natl Acad Sci
, vol.96
, Issue.16
, pp. 9118-9123
-
-
Storms, R.W.1
Trujillo, A.P.2
Springer, J.B.3
Shah, L.4
Colvin, O.M.5
Ludeman, S.M.6
-
55
-
-
0029958876
-
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
-
8666936
-
Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med. 1996;183(4):1797-806.
-
(1996)
J Exp Med
, vol.183
, Issue.4
, pp. 1797-1806
-
-
Goodell, M.A.1
Brose, K.2
Paradis, G.3
Conner, A.S.4
Mulligan, R.C.5
-
56
-
-
0037125973
-
Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo
-
12218177 129446
-
Zhou S, Morris JJ, Barnes Y, Lan L, Schuetz JD, Sorrentino BP. Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo. Proc Natl Acad Sci. 2002;99(19):12339-44.
-
(2002)
Proc Natl Acad Sci
, vol.99
, Issue.19
, pp. 12339-12344
-
-
Zhou, S.1
Morris, J.J.2
Barnes, Y.3
Lan, L.4
Schuetz, J.D.5
Sorrentino, B.P.6
-
57
-
-
0034795256
-
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
-
11533706
-
Zhou S, Schuetz JD, Bunting KD, Colapietro A-M, Sampath J, Morris JJ, et al. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med. 2001;7(9):1028-34.
-
(2001)
Nat Med
, vol.7
, Issue.9
, pp. 1028-1034
-
-
Zhou, S.1
Schuetz, J.D.2
Bunting, K.D.3
Colapietro, A.-M.4
Sampath, J.5
Morris, J.J.6
-
58
-
-
0037079708
-
The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors
-
11781231
-
Scharenberg CW, Harkey MA, Torok-Storb B. The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors. Blood. 2002;99(2):507-12.
-
(2002)
Blood
, vol.99
, Issue.2
, pp. 507-512
-
-
Scharenberg, C.W.1
Harkey, M.A.2
Torok-Storb, B.3
-
59
-
-
0036154828
-
The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells
-
11801536
-
Kim M, Turnquist H, Jackson J, Sgagias M, Yan Y, Gong M, et al. The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells. Clin Cancer Res. 2002;8(1):22-8.
-
(2002)
Clin Cancer Res
, vol.8
, Issue.1
, pp. 22-28
-
-
Kim, M.1
Turnquist, H.2
Jackson, J.3
Sgagias, M.4
Yan, Y.5
Gong, M.6
-
60
-
-
0038823704
-
Direct identification and enrichment of retinal stem cells/progenitors by Hoechst dye efflux assay
-
12766085
-
Bhattacharya S, Jackson JD, Das AV, Thoreson WB, Kuszynski C, James J, et al. Direct identification and enrichment of retinal stem cells/progenitors by Hoechst dye efflux assay. Invest Ophthalmol Vis Sci. 2003;44(6):2764-73.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, Issue.6
, pp. 2764-2773
-
-
Bhattacharya, S.1
Jackson, J.D.2
Das, A.V.3
Thoreson, W.B.4
Kuszynski, C.5
James, J.6
-
61
-
-
0033946139
-
Characterization of neurosphere cell phenotypes by flow cytometry
-
10878568
-
Hulspas R, Quesenberry PJ. Characterization of neurosphere cell phenotypes by flow cytometry. Cytometry. 2000;40(3):245-50.
-
(2000)
Cytometry
, vol.40
, Issue.3
, pp. 245-250
-
-
Hulspas, R.1
Quesenberry, P.J.2
-
62
-
-
34250306257
-
Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
-
17510412
-
Ho MM, Ng AV, Lam S, Hung JY. Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res. 2007;67(10):4827-33.
-
(2007)
Cancer Res
, vol.67
, Issue.10
, pp. 4827-4833
-
-
Ho, M.M.1
Ng, A.V.2
Lam, S.3
Hung, J.Y.4
-
63
-
-
34248529666
-
Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line
-
17440084
-
Wang J, Guo L-P, Chen L-Z, Zeng Y-X, Lu SH. Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line. Cancer Res. 2007;67(8):3716-24.
-
(2007)
Cancer Res
, vol.67
, Issue.8
, pp. 3716-3724
-
-
Wang, J.1
Guo, L.-P.2
Chen, L.-Z.3
Zeng, Y.-X.4
Lu, S.H.5
-
64
-
-
33745924696
-
Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties
-
16799977
-
Chiba T, Kita K, Zheng YW, Yokosuka O, Saisho H, Iwama A, et al. Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties. Hepatology. 2006;44(1):240-51.
-
(2006)
Hepatology
, vol.44
, Issue.1
, pp. 240-251
-
-
Chiba, T.1
Kita, K.2
Zheng, Y.W.3
Yokosuka, O.4
Saisho, H.5
Iwama, A.6
-
65
-
-
1642474273
-
Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line
-
14711994 321758
-
Kondo T, Setoguchi T, Taga T. Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc Natl Acad Sci U S A. 2004;101(3):781-6.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.3
, pp. 781-786
-
-
Kondo, T.1
Setoguchi, T.2
Taga, T.3
-
66
-
-
4644306516
-
A distinct "side population" of cells with high drug efflux capacity in human tumor cells
-
15381773 521140
-
Hirschmann-Jax C, Foster A, Wulf G, Nuchtern J, Jax T, Gobel U, et al. A distinct "side population" of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci U S A. 2004;101(39):14228-33.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.39
, pp. 14228-14233
-
-
Hirschmann-Jax, C.1
Foster, A.2
Wulf, G.3
Nuchtern, J.4
Jax, T.5
Gobel, U.6
-
67
-
-
33746625091
-
Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness
-
16849428 1544057
-
Szotek PP, Pieretti-Vanmarcke R, Masiakos PT, Dinulescu DM, Connolly D, Foster R, et al. Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness. Proc Natl Acad Sci. 2006;103(30):11154-9.
-
(2006)
Proc Natl Acad Sci
, vol.103
, Issue.30
, pp. 11154-11159
-
-
Szotek, P.P.1
Pieretti-Vanmarcke, R.2
Masiakos, P.T.3
Dinulescu, D.M.4
Connolly, D.5
Foster, R.6
-
68
-
-
3042822246
-
Demystifying SP cell purification: Viability, yield, and phenotype are defined by isolation parameters
-
15242769
-
Montanaro F, Liadaki K, Schienda J, Flint A, Gussoni E, Kunkel LM. Demystifying SP cell purification: viability, yield, and phenotype are defined by isolation parameters. Exp Cell Res. 2004;298(1):144-54.
-
(2004)
Exp Cell Res
, vol.298
, Issue.1
, pp. 144-154
-
-
Montanaro, F.1
Liadaki, K.2
Schienda, J.3
Flint, A.4
Gussoni, E.5
Kunkel, L.M.6
-
69
-
-
22244433866
-
Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic
-
16024622
-
Patrawala L, Calhoun T, Schneider-Broussard R, Zhou J, Claypool K, Tang DG. Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic. Cancer Res. 2005;65(14):6207-19.
-
(2005)
Cancer Res
, vol.65
, Issue.14
, pp. 6207-6219
-
-
Patrawala, L.1
Calhoun, T.2
Schneider-Broussard, R.3
Zhou, J.4
Claypool, K.5
Tang, D.G.6
-
70
-
-
0038265441
-
ABCG2 transports sulfated conjugates of steroids and xenobiotics
-
12682043
-
Suzuki M, Suzuki H, Sugimoto Y, Sugiyama Y. ABCG2 transports sulfated conjugates of steroids and xenobiotics. J Biol Chem. 2003;278(25):22644-9.
-
(2003)
J Biol Chem
, vol.278
, Issue.25
, pp. 22644-22649
-
-
Suzuki, M.1
Suzuki, H.2
Sugimoto, Y.3
Sugiyama, Y.4
-
71
-
-
0042856460
-
Breast cancer resistance protein exports sulfated estrogens but not free estrogens
-
12920197
-
Imai Y, Asada S, Tsukahara S, Ishikawa E, Tsuruo T, Sugimoto Y. Breast cancer resistance protein exports sulfated estrogens but not free estrogens. Mol Pharmacol. 2003;64(3):610-8.
-
(2003)
Mol Pharmacol
, vol.64
, Issue.3
, pp. 610-618
-
-
Imai, Y.1
Asada, S.2
Tsukahara, S.3
Ishikawa, E.4
Tsuruo, T.5
Sugimoto, Y.6
-
72
-
-
23044510643
-
Breast cancer resistance protein-mediated efflux of androgen in putative benign and malignant prostate stem cells
-
16061644
-
Huss WJ, Gray DR, Greenberg NM, Mohler JL, Smith GJ. Breast cancer resistance protein-mediated efflux of androgen in putative benign and malignant prostate stem cells. Cancer Res. 2005;65(15):6640-50.
-
(2005)
Cancer Res
, vol.65
, Issue.15
, pp. 6640-6650
-
-
Huss, W.J.1
Gray, D.R.2
Greenberg, N.M.3
Mohler, J.L.4
Smith, G.J.5
-
73
-
-
0038757689
-
Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis
-
12668685
-
Janvilisri T, Venter H, Shahi S, Reuter G, Balakrishnan L, van Veen HW. Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis. J Biol Chem. 2003;278(23):20645-51.
-
(2003)
J Biol Chem
, vol.278
, Issue.23
, pp. 20645-20651
-
-
Janvilisri, T.1
Venter, H.2
Shahi, S.3
Reuter, G.4
Balakrishnan, L.5
Van Veen, H.W.6
-
74
-
-
84886220318
-
Aldehyde dehydrogenase and ATP binding cassette transporter G2 (ABCG2) functional assays isolate different populations of prostate stem cells where ABCG2 function selects for cells with increased stem cell activity
-
24405526 3854760
-
Gangavarapu KJ, Azabdaftari G, Morrison CD, Miller A, Foster BA, Huss WJ. Aldehyde dehydrogenase and ATP binding cassette transporter G2 (ABCG2) functional assays isolate different populations of prostate stem cells where ABCG2 function selects for cells with increased stem cell activity. Stem Cell Res Ther. 2013;4(5):132.
-
(2013)
Stem Cell Res Ther
, vol.4
, Issue.5
, pp. 132
-
-
Gangavarapu, K.J.1
Azabdaftari, G.2
Morrison, C.D.3
Miller, A.4
Foster, B.A.5
Huss, W.J.6
-
75
-
-
34250315214
-
Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo
-
17510410
-
Gu G, Yuan J, Wills M, Kasper S. Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo. Cancer Res. 2007;67(10):4807-15.
-
(2007)
Cancer Res
, vol.67
, Issue.10
, pp. 4807-4815
-
-
Gu, G.1
Yuan, J.2
Wills, M.3
Kasper, S.4
-
76
-
-
60349100648
-
Differential mechanisms of bicalutamide-induced apoptosis in prostate cell lines
-
18475288
-
Floyd MSJ, Teahan S, Fitzpatrick J, Watson R. Differential mechanisms of bicalutamide-induced apoptosis in prostate cell lines. Prostate Cancer Prostatic Dis. 2008;12(1):25-33.
-
(2008)
Prostate Cancer Prostatic Dis
, vol.12
, Issue.1
, pp. 25-33
-
-
Floyd, M.S.J.1
Teahan, S.2
Fitzpatrick, J.3
Watson, R.4
-
77
-
-
0034017624
-
Low-dose twice-daily fractionated X-irradiation of ovarian tumor cells in vitro generates drug-resistant cells overexpressing two multidrug resistance-associated proteins, P-glycoprotein and MRP1
-
10831278
-
Hill BT, Moran E, Etiévant C, Perrin D, Masterson A, Larkin A, et al. Low-dose twice-daily fractionated X-irradiation of ovarian tumor cells in vitro generates drug-resistant cells overexpressing two multidrug resistance-associated proteins, P-glycoprotein and MRP1. Anti-Cancer Drugs. 2000;11(3):193-200.
-
(2000)
Anti-Cancer Drugs
, vol.11
, Issue.3
, pp. 193-200
-
-
Hill, B.T.1
Moran, E.2
Etiévant, C.3
Perrin, D.4
Masterson, A.5
Larkin, A.6
-
78
-
-
0036833896
-
Fractionated irradiation of H69 small-cell lung cancer cells causes stable radiation and drug resistance with increased MRP1, MRP2, and topoisomerase IIα expression
-
12377343
-
Henness S, Davey MW, Harvie RM, Davey RA. Fractionated irradiation of H69 small-cell lung cancer cells causes stable radiation and drug resistance with increased MRP1, MRP2, and topoisomerase IIα expression. Int J Radiat Oncol Biol Phys. 2002;54(3):895-902.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, Issue.3
, pp. 895-902
-
-
Henness, S.1
Davey, M.W.2
Harvie, R.M.3
Davey, R.A.4
-
79
-
-
46449132246
-
Fractionated irradiation can induce functionally relevant multidrug resistance gene and protein expression in human tumor cell lines
-
18582150
-
Bottke D, Koychev D, Busse A, Heufelder K, Wiegel T, Thiel E, et al. Fractionated irradiation can induce functionally relevant multidrug resistance gene and protein expression in human tumor cell lines. Radiat Res. 2008;170(1):41-8.
-
(2008)
Radiat Res
, vol.170
, Issue.1
, pp. 41-48
-
-
Bottke, D.1
Koychev, D.2
Busse, A.3
Heufelder, K.4
Wiegel, T.5
Thiel, E.6
-
80
-
-
36048948042
-
Harnessing drug resistance: Using ABC transporter proteins to target cancer cells
-
17585883 2169513
-
Leitner HM, Kachadourian R, Day BJ. Harnessing drug resistance: using ABC transporter proteins to target cancer cells. Biochem Pharmacol. 2007;74(12):1677-85.
-
(2007)
Biochem Pharmacol
, vol.74
, Issue.12
, pp. 1677-1685
-
-
Leitner, H.M.1
Kachadourian, R.2
Day, B.J.3
-
81
-
-
70349246548
-
Subpopulations of stem-like cells in side population cells from the human bladder transitional cell cancer cell line T24
-
19589244
-
Ning Z, Huang Y, Lin T, Zhou Y, Jiang C, Xu K, et al. Subpopulations of stem-like cells in side population cells from the human bladder transitional cell cancer cell line T24. J Int Med Res. 2009;37(3):621-30.
-
(2009)
J Int Med Res
, vol.37
, Issue.3
, pp. 621-630
-
-
Ning, Z.1
Huang, Y.2
Lin, T.3
Zhou, Y.4
Jiang, C.5
Xu, K.6
-
82
-
-
84978025993
-
ABC transporter activity linked to radiation resistance and molecular subtype in pediatric medulloblastoma
-
24219920 3851566
-
Ingram WJ, Crowther LM, Little EB, Freeman R, Harliwong I, Veleva D, et al. ABC transporter activity linked to radiation resistance and molecular subtype in pediatric medulloblastoma. Exp Hematol Oncol. 2013;2:26.
-
(2013)
Exp Hematol Oncol
, vol.2
, pp. 26
-
-
Ingram, W.J.1
Crowther, L.M.2
Little, E.B.3
Freeman, R.4
Harliwong, I.5
Veleva, D.6
-
83
-
-
0032535004
-
Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C
-
9865745
-
Rabindran SK, He H, Singh M, Brown E, Collins KI, Annable T, et al. Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C. Cancer Res. 1998;58(24):5850-8.
-
(1998)
Cancer Res
, vol.58
, Issue.24
, pp. 5850-5858
-
-
Rabindran, S.K.1
He, H.2
Singh, M.3
Brown, E.4
Collins, K.I.5
Annable, T.6
-
84
-
-
0000890967
-
Potent and Specific Inhibition of the Breast Cancer Resistance Protein Multidrug Transporter in Vitro and in Mouse Intestine by a Novel Analogue of Fumitremorgin C
-
12477054
-
Allen JD, van Loevezijn A, Lakhai JM, van der Valk M, van Tellingen O, Reid G, et al. Potent and Specific Inhibition of the Breast Cancer Resistance Protein Multidrug Transporter in Vitro and in Mouse Intestine by a Novel Analogue of Fumitremorgin C. Mol Cancer Ther. 2002;1(6):417-25.
-
(2002)
Mol Cancer Ther
, vol.1
, Issue.6
, pp. 417-425
-
-
Allen, J.D.1
Van Loevezijn, A.2
Lakhai, J.M.3
Van Der Valk, M.4
Van Tellingen, O.5
Reid, G.6
-
86
-
-
68749104738
-
Influence of the dual ABCB1 and ABCG2 inhibitor tariquidar on the disposition of oral imatinib in mice
-
19591692 2717937
-
Gardner ER, Smith NF, Figg WD, Sparreboom A. Influence of the dual ABCB1 and ABCG2 inhibitor tariquidar on the disposition of oral imatinib in mice. J Exp Clin Cancer Res. 2009;28(1):99.
-
(2009)
J Exp Clin Cancer Res
, vol.28
, Issue.1
, pp. 99
-
-
Gardner, E.R.1
Smith, N.F.2
Figg, W.D.3
Sparreboom, A.4
-
87
-
-
59649129538
-
Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2
-
18971320 2680522
-
Shukla S, Robey RW, Bates SE, Ambudkar SV. Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2. Drug Metab Dispos. 2009;37(2):359-65.
-
(2009)
Drug Metab Dispos
, vol.37
, Issue.2
, pp. 359-365
-
-
Shukla, S.1
Robey, R.W.2
Bates, S.E.3
Ambudkar, S.V.4
-
88
-
-
84894413523
-
Interaction of the efflux transporters ABCB1 and ABCG2 with imatinib, nilotinib, and dasatinib
-
24107928
-
Eadie L, Hughes T, White D. Interaction of the efflux transporters ABCB1 and ABCG2 with imatinib, nilotinib, and dasatinib. Clin Pharmacol Ther. 2014;95(3):294-306.
-
(2014)
Clin Pharmacol Ther
, vol.95
, Issue.3
, pp. 294-306
-
-
Eadie, L.1
Hughes, T.2
White, D.3
-
89
-
-
77954892297
-
Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib
-
20423956 2913625
-
Dohse M, Scharenberg C, Shukla S, Robey RW, Volkmann T, Deeken JF, et al. Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib. Drug Metab Dispos. 2010;38(8):1371-80.
-
(2010)
Drug Metab Dispos
, vol.38
, Issue.8
, pp. 1371-1380
-
-
Dohse, M.1
Scharenberg, C.2
Shukla, S.3
Robey, R.W.4
Volkmann, T.5
Deeken, J.F.6
-
90
-
-
1942506722
-
Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro
-
15059881
-
Houghton PJ, Germain GS, Harwood FC, Schuetz JD, Stewart CF, Buchdunger E, et al. Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro. Cancer Res. 2004;64(7):2333-7.
-
(2004)
Cancer Res
, vol.64
, Issue.7
, pp. 2333-2337
-
-
Houghton, P.J.1
Germain, G.S.2
Harwood, F.C.3
Schuetz, J.D.4
Stewart, C.F.5
Buchdunger, E.6
-
91
-
-
84885607372
-
Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump
-
23960095
-
Mazard T, Causse A, Simony J, Leconet W, Vezzio-Vie N, Torro A, et al. Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump. Mol Cancer Ther. 2013;12(10):2121-34.
-
(2013)
Mol Cancer Ther
, vol.12
, Issue.10
, pp. 2121-2134
-
-
Mazard, T.1
Causse, A.2
Simony, J.3
Leconet, W.4
Vezzio-Vie, N.5
Torro, A.6
-
92
-
-
84876089340
-
Fluorouracil, leucovorin, and irinotecan plus either sunitinib or placebo in metastatic colorectal cancer: A randomized, phase III trial
-
23358972
-
Carrato A, Swieboda-Sadlej A, Staszewska-Skurczynska M, Lim R, Roman L, Shparyk Y, et al. Fluorouracil, leucovorin, and irinotecan plus either sunitinib or placebo in metastatic colorectal cancer: a randomized, phase III trial. J Clin Oncol. 2013;31(10):1341-7.
-
(2013)
J Clin Oncol
, vol.31
, Issue.10
, pp. 1341-1347
-
-
Carrato, A.1
Swieboda-Sadlej, A.2
Staszewska-Skurczynska, M.3
Lim, R.4
Roman, L.5
Shparyk, Y.6
-
93
-
-
84895803636
-
Sorafenib and irinotecan (NEXIRI) as second-or later-line treatment for patients with metastatic colorectal cancer and KRAS-mutated tumours: A multicentre Phase I/II trial
-
24407191 3950852
-
Samalin E, Bouché O, Thézenas S, Francois E, Adenis A, Bennouna J, et al. Sorafenib and irinotecan (NEXIRI) as second-or later-line treatment for patients with metastatic colorectal cancer and KRAS-mutated tumours: a multicentre Phase I/II trial. Br J Cancer. 2014;110(5):1148-54.
-
(2014)
Br J Cancer
, vol.110
, Issue.5
, pp. 1148-1154
-
-
Samalin, E.1
Bouché, O.2
Thézenas, S.3
Francois, E.4
Adenis, A.5
Bennouna, J.6
-
94
-
-
0028231401
-
Reversal of drug sensitivity in multidrug-resistant tumor cells by an MDR1 (PGY1) ribozyme
-
8118816
-
Kobayashi H, Dorai T, Holland JF, Ohnuma T. Reversal of drug sensitivity in multidrug-resistant tumor cells by an MDR1 (PGY1) ribozyme. Cancer Res. 1994;54(5):1271-5.
-
(1994)
Cancer Res
, vol.54
, Issue.5
, pp. 1271-1275
-
-
Kobayashi, H.1
Dorai, T.2
Holland, J.F.3
Ohnuma, T.4
-
95
-
-
63849208629
-
Silencing the breast cancer resistance protein expression and function in caco-2 cells using lentiviral vector-based short hairpin RNA
-
19131524
-
Zhang W, Li J, Allen SM, Weiskircher EA, Huang Y, George RA, et al. Silencing the breast cancer resistance protein expression and function in caco-2 cells using lentiviral vector-based short hairpin RNA. Drug Metab Dispos. 2009;37(4):737-44.
-
(2009)
Drug Metab Dispos
, vol.37
, Issue.4
, pp. 737-744
-
-
Zhang, W.1
Li, J.2
Allen, S.M.3
Weiskircher, E.A.4
Huang, Y.5
George, R.A.6
-
96
-
-
33751071871
-
Complete reversal of ABCG2-depending atypical multidrug resistance by RNA interference in human carcinoma cells
-
16978089
-
Priebsch A, Rompe F, Tönnies H, Kowalski P, Surowiak P, Stege A, et al. Complete reversal of ABCG2-depending atypical multidrug resistance by RNA interference in human carcinoma cells. Oligonucleotides. 2006;16(3):263-74.
-
(2006)
Oligonucleotides
, vol.16
, Issue.3
, pp. 263-274
-
-
Priebsch, A.1
Rompe, F.2
Tönnies, H.3
Kowalski, P.4
Surowiak, P.5
Stege, A.6
-
97
-
-
12344330537
-
Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference
-
15634651
-
Ee PR, He X, Ross DD, Beck WT. Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference. Mol Cancer Ther. 2004;3(12):1577-84.
-
(2004)
Mol Cancer Ther
, vol.3
, Issue.12
, pp. 1577-1584
-
-
Ee, P.R.1
He, X.2
Ross, D.D.3
Beck, W.T.4
-
98
-
-
20144362553
-
Modulation of BCRP mediated atypical multidrug resistance phenotype by RNA interference
-
Li W, Zhou G, Song X, Chi W, Ren R, Wang X. Modulation of BCRP mediated atypical multidrug resistance phenotype by RNA interference. Neoplasma. 2004;52(3):219-24.
-
(2004)
Neoplasma
, vol.52
, Issue.3
, pp. 219-224
-
-
Li, W.1
Zhou, G.2
Song, X.3
Chi, W.4
Ren, R.5
Wang, X.6
-
100
-
-
58749104364
-
The promises and pitfalls of RNA-interference-based therapeutics
-
19158789 2702667
-
Castanotto D, Rossi JJ. The promises and pitfalls of RNA-interference-based therapeutics. Nature. 2009;457(7228):426-33.
-
(2009)
Nature
, vol.457
, Issue.7228
, pp. 426-433
-
-
Castanotto, D.1
Rossi, J.J.2
-
101
-
-
77951132901
-
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
-
20305636 2855406
-
Davis ME, Zuckerman JE, Choi CHJ, Seligson D, Tolcher A, Alabi CA, et al. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature. 2010;464(7291):1067-70.
-
(2010)
Nature
, vol.464
, Issue.7291
, pp. 1067-1070
-
-
Davis, M.E.1
Zuckerman, J.E.2
Choi, C.H.J.3
Seligson, D.4
Tolcher, A.5
Alabi, C.A.6
-
102
-
-
84877120847
-
First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement
-
23358650
-
Tabernero J, Shapiro GI, LoRusso PM, Cervantes A, Schwartz GK, Weiss GJ, et al. First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement. Cancer Discov. 2013;3(4):406-17.
-
(2013)
Cancer Discov
, vol.3
, Issue.4
, pp. 406-417
-
-
Tabernero, J.1
Shapiro, G.I.2
LoRusso, P.M.3
Cervantes, A.4
Schwartz, G.K.5
Weiss, G.J.6
-
103
-
-
33745953739
-
Complex interaction of BCRP/ABCG2 and imatinib in BCR-ABL-expressing cells: BCRP-mediated resistance to imatinib is attenuated by imatinib-induced reduction of BCRP expression
-
16543472
-
Nakanishi T, Shiozawa K, Hassel BA, Ross DD. Complex interaction of BCRP/ABCG2 and imatinib in BCR-ABL-expressing cells: BCRP-mediated resistance to imatinib is attenuated by imatinib-induced reduction of BCRP expression. Blood. 2006;108(2):678-84.
-
(2006)
Blood
, vol.108
, Issue.2
, pp. 678-684
-
-
Nakanishi, T.1
Shiozawa, K.2
Hassel, B.A.3
Ross, D.D.4
-
104
-
-
0034730755
-
The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides
-
10893247
-
Jedlitschky G, Burchell B, Keppler D. The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides. J Biol Chem. 2000;275(39):30069-74.
-
(2000)
J Biol Chem
, vol.275
, Issue.39
, pp. 30069-30074
-
-
Jedlitschky, G.1
Burchell, B.2
Keppler, D.3
-
105
-
-
0035823559
-
Transport of cyclic nucleotides and estradiol 17-β-D-glucuronide by multidrug resistance protein 4 resistance to 6-mercaptopurine and 6-thioguanine
-
11447229
-
Chen Z-S, Lee K, Kruh GD. Transport of cyclic nucleotides and estradiol 17-β-D-glucuronide by multidrug resistance protein 4 resistance to 6-mercaptopurine and 6-thioguanine. J Biol Chem. 2001;276(36):33747-54.
-
(2001)
J Biol Chem
, vol.276
, Issue.36
, pp. 33747-33754
-
-
Chen, Z.-S.1
Lee, K.2
Kruh, G.D.3
-
106
-
-
79954569834
-
Sildenafil reverses ABCB1-and ABCG2-mediated chemotherapeutic drug resistance
-
21402712 3078184
-
Shi Z, Tiwari AK, Shukla S, Robey RW, Singh S, Kim I-W, et al. Sildenafil reverses ABCB1-and ABCG2-mediated chemotherapeutic drug resistance. Cancer Res. 2011;71(8):3029-41.
-
(2011)
Cancer Res
, vol.71
, Issue.8
, pp. 3029-3041
-
-
Shi, Z.1
Tiwari, A.K.2
Shukla, S.3
Robey, R.W.4
Singh, S.5
Kim, I.-W.6
-
107
-
-
84857427753
-
Xanthines down-regulate the drug transporter ABCG2 and reverse multidrug resistance
-
22113078 3286305
-
Ding R, Shi J, Pabon K, Scotto KW. Xanthines down-regulate the drug transporter ABCG2 and reverse multidrug resistance. Mol Pharmacol. 2012;81(3):328-37.
-
(2012)
Mol Pharmacol
, vol.81
, Issue.3
, pp. 328-337
-
-
Ding, R.1
Shi, J.2
Pabon, K.3
Scotto, K.W.4
-
108
-
-
77956319059
-
Cabazitaxel
-
20811375
-
Galsky MD, Dritselis A, Kirkpatrick P, Oh WK. Cabazitaxel. Nat Rev Drug Discov. 2010;9(9):677-8.
-
(2010)
Nat Rev Drug Discov
, vol.9
, Issue.9
, pp. 677-678
-
-
Galsky, M.D.1
Dritselis, A.2
Kirkpatrick, P.3
Oh, W.K.4
-
109
-
-
77957682309
-
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
-
20888992
-
de Bono JS, Oudard S, Ozguroglu M, Hansen S, Machiels J-P, Kocak I, et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet. 2010;376(9747):1147-54.
-
(2010)
Lancet
, vol.376
, Issue.9747
, pp. 1147-1154
-
-
De Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
Hansen, S.4
Machiels, J.-P.5
Kocak, I.6
-
110
-
-
2942537702
-
Novel camptothecin analogues that circumvent ABCG2-associated drug resistance in human tumor cells
-
15170677
-
Yoshikawa M, Ikegami Y, Hayasaka S, Ishii K, Ito A, Sano K, et al. Novel camptothecin analogues that circumvent ABCG2-associated drug resistance in human tumor cells. Int J Cancer. 2004;110(6):921-7.
-
(2004)
Int J Cancer
, vol.110
, Issue.6
, pp. 921-927
-
-
Yoshikawa, M.1
Ikegami, Y.2
Hayasaka, S.3
Ishii, K.4
Ito, A.5
Sano, K.6
-
111
-
-
71349087273
-
A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts
-
19495753
-
Endo M, Miwa M, Ura M, Tanimura H, Taniguchi K, Miyazaki Y, et al. A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts. Cancer Chemother Pharmacol. 2010;65(2):363-71.
-
(2010)
Cancer Chemother Pharmacol
, vol.65
, Issue.2
, pp. 363-371
-
-
Endo, M.1
Miwa, M.2
Ura, M.3
Tanimura, H.4
Taniguchi, K.5
Miyazaki, Y.6
-
112
-
-
79952783035
-
14-Aminocamptothecins: Their synthesis, preclinical activity, and potential use for cancer treatment
-
21341674
-
Duan J-X, Cai X, Meng F, Sun JD, Liu Q, Jung D, et al. 14-Aminocamptothecins: Their synthesis, preclinical activity, and potential use for cancer treatment. J Med Chem. 2011;54(6):1715-23.
-
(2011)
J Med Chem
, vol.54
, Issue.6
, pp. 1715-1723
-
-
Duan, J.-X.1
Cai, X.2
Meng, F.3
Sun, J.D.4
Liu, Q.5
Jung, D.6
-
113
-
-
37549071516
-
Novel E-ring camptothecin keto analogues (S38809 and S39625) are stable, potent, and selective topoisomerase i inhibitors without being substrates of drug efflux transporters
-
18089716
-
Takagi K, Dexheimer TS, Redon C, Sordet O, Agama K, Lavielle G, et al. Novel E-ring camptothecin keto analogues (S38809 and S39625) are stable, potent, and selective topoisomerase I inhibitors without being substrates of drug efflux transporters. Mol Cancer Ther. 2007;6(12):3229-38.
-
(2007)
Mol Cancer Ther
, vol.6
, Issue.12
, pp. 3229-3238
-
-
Takagi, K.1
Dexheimer, T.S.2
Redon, C.3
Sordet, O.4
Agama, K.5
Lavielle, G.6
-
114
-
-
84866534987
-
A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity
-
23029106 3446924
-
Ling X, Cao S, Cheng Q, Keefe JT, Rustum YM, Li F. A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity. PLoS One. 2012;7(9):e45571.
-
(2012)
PLoS One
, vol.7
, Issue.9
, pp. e45571
-
-
Ling, X.1
Cao, S.2
Cheng, Q.3
Keefe, J.T.4
Rustum, Y.M.5
Li, F.6
-
115
-
-
84917706732
-
FL118 Induces p53-Dependent Senescence in Colorectal Cancer Cells by Promoting Degradation of MdmX
-
25512388 4448973
-
Ling X, Xu C, Fan C, Zhong K, Li F, Wang X. FL118 Induces p53-Dependent Senescence in Colorectal Cancer Cells by Promoting Degradation of MdmX. Cancer Res. 2014;74(24):7487-97.
-
(2014)
Cancer Res
, vol.74
, Issue.24
, pp. 7487-7497
-
-
Ling, X.1
Xu, C.2
Fan, C.3
Zhong, K.4
Li, F.5
Wang, X.6
-
116
-
-
84893267704
-
Antitumor Activity of FL118, a Survivin, Mcl-1, XIAP, and cIAP2 Selective Inhibitor, Is Highly Dependent on Its Primary Structure and Steric Configuration
-
24329001
-
Zhao J, Ling X, Cao S, Liu X, Wan S, Jiang T, et al. Antitumor Activity of FL118, a Survivin, Mcl-1, XIAP, and cIAP2 Selective Inhibitor, Is Highly Dependent on Its Primary Structure and Steric Configuration. Mol Pharm. 2014;11(2):457-67.
-
(2014)
Mol Pharm
, vol.11
, Issue.2
, pp. 457-467
-
-
Zhao, J.1
Ling, X.2
Cao, S.3
Liu, X.4
Wan, S.5
Jiang, T.6
-
117
-
-
84875772988
-
An intravenous (IV) route-compatible formulation of FL118, a survIVin, Mcl-1, XIAP, and cIAP2 selectIVe inhibitor, improves FL118 antitumor efficacy and therapeutic index (TI)
-
23573360 3612511
-
Ling X, Li F. An intravenous (iv) route-compatible formulation of FL118, a survivin, Mcl-1, XIAP, and cIAP2 selective inhibitor, improves FL118 antitumor efficacy and therapeutic index (TI). Am J Transl Res. 2013;5(2):139-54.
-
(2013)
Am J Transl Res
, vol.5
, Issue.2
, pp. 139-154
-
-
Ling, X.1
Li, F.2
-
118
-
-
84929145820
-
FL118, a novel camptothecin derivative, is insensitive to ABCG2 expression and shows improved efficacy in comparison with irinotecan in colon and lung cancer models with ABCG2-induced resistance
-
25928015 4427926
-
Westover D, Ling X, Lam H, Welch J, Jin C, Gongora C, et al. FL118, a novel camptothecin derivative, is insensitive to ABCG2 expression and shows improved efficacy in comparison with irinotecan in colon and lung cancer models with ABCG2-induced resistance. Mol Cancer. 2015;14(1):92.
-
(2015)
Mol Cancer
, vol.14
, Issue.1
, pp. 92
-
-
Westover, D.1
Ling, X.2
Lam, H.3
Welch, J.4
Jin, C.5
Gongora, C.6
-
119
-
-
84947803678
-
FL118, a novel camptothecin analogue, overcomes irinotecan and topotecan resistance in human xenograft models
-
26692923 4656756
-
Ling X, Liu X, Zhong K, Smith N, Prey J, Li F. FL118, a novel camptothecin analogue, overcomes irinotecan and topotecan resistance in human xenograft models. Am J Transl Res. 2015;7(10):1765-81.
-
(2015)
Am J Transl Res
, vol.7
, Issue.10
, pp. 1765-1781
-
-
Ling, X.1
Liu, X.2
Zhong, K.3
Smith, N.4
Prey, J.5
Li, F.6
-
120
-
-
84861097763
-
Strongly amphiphilic photosensitizers are not substrates of the cancer stem cell marker ABCG2 and provides specific and efficient light-triggered drug delivery of an EGFR-targeted cytotoxic drug
-
22349185
-
Selbo PK, Weyergang A, Eng MS, Bostad M, Mælandsmo GM, Høgset A, et al. Strongly amphiphilic photosensitizers are not substrates of the cancer stem cell marker ABCG2 and provides specific and efficient light-triggered drug delivery of an EGFR-targeted cytotoxic drug. J Control Release. 2012;159(2):197-203.
-
(2012)
J Control Release
, vol.159
, Issue.2
, pp. 197-203
-
-
Selbo, P.K.1
Weyergang, A.2
Eng, M.S.3
Bostad, M.4
Mælandsmo, G.M.5
Høgset, A.6
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