-
1
-
-
0032404092
-
A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
-
ALLIKMETS, R., SCHRIML, L.M., HUTCHINSON, A., ROMANO-SPICA, V., and DEAN, M. (1998). A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Cancer Res. 58, 5337-5339.
-
(1998)
Cancer Res.
, vol.58
, pp. 5337-5339
-
-
Allikmets, R.1
Schriml, L.M.2
Hutchinson, A.3
Romano-Spica, V.4
Dean, M.5
-
2
-
-
0014767029
-
Cellular resistance to actinomycin D in Chinese hamster cells in vitro: Cross-resistance, radioautographic, and cytogenetic studies
-
BIEDLER, J.L., and RIEHM, H. (1970). Cellular resistance to actinomycin D in Chinese hamster cells in vitro: Cross-resistance, radioautographic, and cytogenetic studies. Cancer Res. 30, 1174-1184.
-
(1970)
Cancer Res.
, vol.30
, pp. 1174-1184
-
-
Biedler, J.L.1
Riehm, H.2
-
3
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
BRUMMELKAMP, T.R., BERNARDS, R., and AGAMI, R. (2002). A system for stable expression of short interfering RNAs in mammalian cells. Science 296, 550-553.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
4
-
-
0025322402
-
Characterization of Adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein
-
CHEN, Y.N., MICKLEY, L.A., SCHWARTZ, A.M., ACTON, E.M., HWANG, J.L., and FOJO, A.T. (1990). Characterization of Adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein. J. Biol. Chem. 265, 10073-10080.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 10073-10080
-
-
Chen, Y.N.1
Mickley, L.A.2
Schwartz, A.M.3
Acton, E.M.4
Hwang, J.L.5
Fojo, A.T.6
-
5
-
-
0033759405
-
Production of first generation adenovirus vectors: A review
-
DANTHINNE, X., and IMPERIALE, M.J. (2000). Production of first generation adenovirus vectors: A review. Gene Ther. 27, 1707-1714.
-
(2000)
Gene Ther.
, vol.27
, pp. 1707-1714
-
-
Danthinne, X.1
Imperiale, M.J.2
-
6
-
-
0025175599
-
Membrane vesicle formation due to acquired mitoxantrone resistance in human gastric carcinoma cell line EPG85-257
-
DIETEL, M., ARPS, H., LAGE, H., and NIENDORF, A. (1990). Membrane vesicle formation due to acquired mitoxantrone resistance in human gastric carcinoma cell line EPG85-257. Cancer Res. 50, 6100-6106.
-
(1990)
Cancer Res.
, vol.50
, pp. 6100-6106
-
-
Dietel, M.1
Arps, H.2
Lage, H.3
Niendorf, A.4
-
7
-
-
12344330537
-
Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference
-
EE, P.L., HE, X., ROSS, D.D., and BECK, W.T. (2004). Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference. Mol. Cancer Ther. 3, 1577-1583.
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 1577-1583
-
-
Ee, P.L.1
He, X.2
Ross, D.D.3
Beck, W.T.4
-
8
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
ELBASHIR, S.M., HARBORTH, J., LENDECKEL, W., YALCIN, A., WEBER, K., and TUSCHL, T. (2001). Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
9
-
-
0036176510
-
Mechanisms of cancer drug resistance
-
GOTTESMAN, M.M. (2002). Mechanisms of cancer drug resistance. Annu. Rev. Med. 53, 615-627.
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 615-627
-
-
Gottesman, M.M.1
-
10
-
-
0035694237
-
Identification of essential genes in cultured mammalian cells using small interfering RNAs
-
HARBORTH, J., ELBASHIR, S.M., BECHERT, K., TUSCHL, T., and WEBER, K. (2001). Identification of essential genes in cultured mammalian cells using small interfering RNAs. J. Cell Sci. 114, 4557-4565.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 4557-4565
-
-
Harborth, J.1
Elbashir, S.M.2
Bechert, K.3
Tuschl, T.4
Weber, K.5
-
11
-
-
0038072903
-
The reversal of multidrug resistance: An update
-
KELLEN, J. A. (2003). The reversal of multidrug resistance: An update. J. Exp. Ther. Oncol. 3, 5-13.
-
(2003)
J. Exp. Ther. Oncol.
, vol.3
, pp. 5-13
-
-
Kellen, J.A.1
-
12
-
-
0030922194
-
Decreased drug accumulation in a mitoxantrone-resistant gastric carcinoma cell line in the absence of P-glycoprotein
-
KELLNER, U., HUTCHINSON, L., SEIDEL, A., LAGE, H., DANKS, M.K., DIETEL, M., and KAUFMANN, S.C. (1997). Decreased drug accumulation in a mitoxantrone-resistant gastric carcinoma cell line in the absence of P-glycoprotein. Int. J. Cancer 71, 817-824.
-
(1997)
Int. J. Cancer
, vol.71
, pp. 817-824
-
-
Kellner, U.1
Hutchinson, L.2
Seidel, A.3
Lage, H.4
Danks, M.K.5
Dietel, M.6
Kaufmann, S.C.7
-
13
-
-
0035049256
-
Selection and characterization of a high-activity ribozyme directed against the antineoplastic drug resistance-associated ABC transporter BCRP/MXR/ABCG2
-
KOWALSKI, P., WICHERT, A., HOLM, P.S., DIETEL, M., and LAGE, H. (2001). Selection and characterization of a high-activity ribozyme directed against the antineoplastic drug resistance-associated ABC transporter BCRP/MXR/ABCG2. Cancer Gene Ther. 8, 185-192.
-
(2001)
Cancer Gene Ther.
, vol.8
, pp. 185-192
-
-
Kowalski, P.1
Wichert, A.2
Holm, P.S.3
Dietel, M.4
Lage, H.5
-
14
-
-
0036019374
-
Modulation of the atypical multidrug-resistant phenotype by a hammerhead ribozyme directed against the ABC transporter BCRP/MXR/ABCG2
-
KOWALSKI, P., STEIN, U., SCHEFFER, G.L., and LAGE, H. (2002). Modulation of the atypical multidrug-resistant phenotype by a hammerhead ribozyme directed against the ABC transporter BCRP/MXR/ABCG2. Cancer Gene Ther. 9, 579-586.
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 579-586
-
-
Kowalski, P.1
Stein, U.2
Scheffer, G.L.3
Lage, H.4
-
15
-
-
4444370277
-
Effective knock down of very high ABCG2 expression by a hammerhead ribozyme
-
KOWALSKI, P., FARLEY, K.M., LAGE, H., and SCHNEIDER, E. (2004). Effective knock down of very high ABCG2 expression by a hammerhead ribozyme. Anticancer Res. 24, 2231-2235.
-
(2004)
Anticancer Res.
, vol.24
, pp. 2231-2235
-
-
Kowalski, P.1
Farley, K.M.2
Lage, H.3
Schneider, E.4
-
16
-
-
14844360548
-
Reversal of different drug-resistant phenotypes by an autocatalytic multitarget multiribozyme directed against the transcripts of the ABC transporters MDR1/P-gp, MRP2, and BCRP
-
KOWALSKI, P., SUROWIAK, P., and LAGE, H. (2005). Reversal of different drug-resistant phenotypes by an autocatalytic multitarget multiribozyme directed against the transcripts of the ABC transporters MDR1/P-gp, MRP2, and BCRP. Mol. Ther. 11, 508-522.
-
(2005)
Mol. Ther.
, vol.11
, pp. 508-522
-
-
Kowalski, P.1
Surowiak, P.2
Lage, H.3
-
17
-
-
0042161890
-
The activity of siRNA in mammalian cells is related to structural target accessibility: A comparison with antisense oligonucleotides
-
KRETSCHMER-KAZEMI FAR, R., and SCZAKIEL, G. (2003). The activity of siRNA in mammalian cells is related to structural target accessibility: A comparison with antisense oligonucleotides. Nucleic Acids Res. 31, 4417-4424.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 4417-4424
-
-
Kretschmer-Kazemi Far, R.1
Sczakiel, G.2
-
18
-
-
0041833334
-
ABC-transporters: Implications on drug resistance from microorganisms to human cancers
-
LAGE, H. (2003a). ABC-transporters: Implications on drug resistance from microorganisms to human cancers. Int. J. Antimicrob. Agents 22, 188-199.
-
(2003)
Int. J. Antimicrob. Agents
, vol.22
, pp. 188-199
-
-
Lage, H.1
-
19
-
-
1142310555
-
Molecular analysis of therapy resistance in gastric cancer
-
LAGE, H. (2003b). Molecular analysis of therapy resistance in gastric cancer. Digest. Dis. 21, 326-338.
-
(2003)
Digest. Dis.
, vol.21
, pp. 326-338
-
-
Lage, H.1
-
20
-
-
85047689435
-
Potential applications of RNA interference technology in the treatment of cancer
-
LAGE, H. (2005). Potential applications of RNA interference technology in the treatment of cancer. Future Oncol. 1, 103-113.
-
(2005)
Future Oncol.
, vol.1
, pp. 103-113
-
-
Lage, H.1
-
21
-
-
33745756680
-
MDR1/P-glycoprotein (ABCB1) as target for RNA interference-mediated reversal of multidrug resistance
-
LAGE, H. (2006). MDR1/P-glycoprotein (ABCB1) as target for RNA interference-mediated reversal of multidrug resistance. Curr. Drug Targets 7, 813-821.
-
(2006)
Curr. Drug Targets
, vol.7
, pp. 813-821
-
-
Lage, H.1
-
22
-
-
0034334325
-
Effect of the breast cancer resistance protein on atypical multidrug resistance
-
LAGE, H., and DIETEL, M. (2000). Effect of the breast cancer resistance protein on atypical multidrug resistance. Lancet Oncol. 1, 169-175.
-
(2000)
Lancet Oncol.
, vol.1
, pp. 169-175
-
-
Lage, H.1
Dietel, M.2
-
23
-
-
33646505540
-
High antineoplastic activity of new heterocyclic compounds in cancer cells with resistance against classical DNA topoisomerase II-targeting drugs
-
LAGE, H., AKI-SENER, E., and YALCIN, I. (2006). High antineoplastic activity of new heterocyclic compounds in cancer cells with resistance against classical DNA topoisomerase II-targeting drugs. Int. J. Cancer 119, 213-220.
-
(2006)
Int. J. Cancer
, vol.119
, pp. 213-220
-
-
Lage, H.1
Aki-Sener, E.2
Yalcin, I.3
-
24
-
-
20144362553
-
Modulation of BCRP mediated atypical multidrug resistance phenotype by RNA interference
-
LI, W.T., ZHOU, G.Y., SONG, X.R., CHI, W.L., REN, R.M., and WANG, X.W. (2005). Modulation of BCRP mediated atypical multidrug resistance phenotype by RNA interference. Neoplasma 52, 219-224.
-
(2005)
Neoplasma
, vol.52
, pp. 219-224
-
-
Li, W.T.1
Zhou, G.Y.2
Song, X.R.3
Chi, W.L.4
Ren, R.M.5
Wang, X.W.6
-
25
-
-
4644223259
-
Mechanisms of gene silencing by double-stranded RNA
-
MEISTER, G., and TUSCHL, T. (2004). Mechanisms of gene silencing by double-stranded RNA. Nature 431, 343-349.
-
(2004)
Nature
, vol.431
, pp. 343-349
-
-
Meister, G.1
Tuschl, T.2
-
26
-
-
0842346326
-
Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells
-
MURATOVSKA, A., and ECCLES, M.R. (2004). Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells. FEBS Lett. 558, 63-68.
-
(2004)
FEBS Lett.
, vol.558
, pp. 63-68
-
-
Muratovska, A.1
Eccles, M.R.2
-
27
-
-
0026496549
-
Reduced intracellular drug accumulation in the absence of P-glycoprotein (mdr1) overexpression in mitoxantrone-resistant human MCF-7 breast cancer cells
-
NAKAGAWA, M., SCHNEIDER, E., DIXON, K.H., HORTON, J., KELLEY, K., MORROW, C., and COWAN, K.H. (1992). Reduced intracellular drug accumulation in the absence of P-glycoprotein (mdr1) overexpression in mitoxantrone-resistant human MCF-7 breast cancer cells. Cancer Res. 52, 6175-6181.
-
(1992)
Cancer Res.
, vol.52
, pp. 6175-6181
-
-
Nakagawa, M.1
Schneider, E.2
Dixon, K.H.3
Horton, J.4
Kelley, K.5
Morrow, C.6
Cowan, K.H.7
-
28
-
-
19544393343
-
Induction of the ABC-transporters Mdr1/P-gp (Abcb1), mrp1 (Abcc1), and bcrp (Abcg2) during establishment of multidrug resistance following exposure to mitoxantrone
-
NIETH, C., and LAGE, H. (2005). Induction of the ABC-transporters Mdr1/P-gp (Abcb1), mrp1 (Abcc1), and bcrp (Abcg2) during establishment of multidrug resistance following exposure to mitoxantrone. J. Chemother. 17, 215-223.
-
(2005)
J. Chemother.
, vol.17
, pp. 215-223
-
-
Nieth, C.1
Lage, H.2
-
29
-
-
0037526598
-
Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi)
-
NIETH, C., PRIEBSCH, A., STEGE, A., and LAGE, H. (2003). Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi). FEBS Lett. 545, 144-150.
-
(2003)
FEBS Lett.
, vol.545
, pp. 144-150
-
-
Nieth, C.1
Priebsch, A.2
Stege, A.3
Lage, H.4
-
30
-
-
0242331085
-
Multidrug resistance reversal agents
-
ROBERT, J., and JARRY, C. (2003). Multidrug resistance reversal agents. J. Med. Chem. 46, 4805-4817.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 4805-4817
-
-
Robert, J.1
Jarry, C.2
-
31
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
SKEHAN, P., STORENG, R., SCUDIERO, D., MONKS, A., MCMAHON, J., VISTICA, D., WARREN, J.T., BOKESCH, H., KENNEY, S., and BOYD, M.R. (1990). New colorimetric cytotoxicity assay for anticancer-drug screening. J. Natl. Cancer Inst. 82, 1107-1112.
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
Mcmahon, J.5
Vistica, D.6
Warren, J.T.7
Bokesch, H.8
Kenney, S.9
Boyd, M.R.10
-
32
-
-
8444227866
-
Stable and complete overcoming of MDR1/P-glycoprotein-mediated multidrug resistance in human gastric carcinoma cells by RNA interference
-
STEGE, A., PRIEBSCH, A., NIETH, C., and LAGE, H. (2004). Stable and complete overcoming of MDR1/P-glycoprotein-mediated multidrug resistance in human gastric carcinoma cells by RNA interference. Cancer Gene Ther. 11, 699-706.
-
(2004)
Cancer Gene Ther.
, vol.11
, pp. 699-706
-
-
Stege, A.1
Priebsch, A.2
Nieth, C.3
Lage, H.4
-
33
-
-
0034033621
-
A novel, long-circulating, and functional liposomal formulation of antisense oligodeoxynucleotides targeted against MDR1
-
STUART, D.D., KAO, G.Y., and ALLEN, T.M. (2000). A novel, long-circulating, and functional liposomal formulation of antisense oligodeoxynucleotides targeted against MDR1. Cancer Gene Ther. 7, 466-475.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 466-475
-
-
Stuart, D.D.1
Kao, G.Y.2
Allen, T.M.3
-
34
-
-
0037358040
-
Overcoming multidrug resistance in cancer: An update on the clinical strategy of inhibiting P-glycoprotein
-
THOMAS, H., and COLEY, H.M. (2003). Overcoming multidrug resistance in cancer: An update on the clinical strategy of inhibiting P-glycoprotein. Cancer Control 10, 159-165.
-
(2003)
Cancer Control
, vol.10
, pp. 159-165
-
-
Thomas, H.1
Coley, H.M.2
-
35
-
-
0042193659
-
Characterization of a supernumerary ring chromosome 1 mosaicism in two cell systems by molecular cytogenetic techniques and review of the literature
-
TÖNNIES, H., NEUMANN, L.M., GRUNEBERG, B., and NEITZEL, H. (2003a). Characterization of a supernumerary ring chromosome 1 mosaicism in two cell systems by molecular cytogenetic techniques and review of the literature. Am. J. Med. Genet. A 121, 163-167.
-
(2003)
Am. J. Med. Genet. A
, vol.121
, pp. 163-167
-
-
Tönnies, H.1
Neumann, L.M.2
Gruneberg, B.3
Neitzel, H.4
-
36
-
-
0037350309
-
Association of genomic imbalances with drug resistance and thermoresistance in human gastric carcinoma cells
-
TÖNNIES, H., POLAND, J., SINHA, P., and LAGE, H. (2003b). Association of genomic imbalances with drug resistance and thermoresistance in human gastric carcinoma cells. Int. J. Cancer 103, 752-758.
-
(2003)
Int. J. Cancer
, vol.103
, pp. 752-758
-
-
Tönnies, H.1
Poland, J.2
Sinha, P.3
Lage, H.4
-
37
-
-
0035117313
-
Nonviral in vivo gene delivery into tumors using a novel low volume jet-injection technology
-
WALTHER, W., STEIN, U., FICHTNER, I., MALCHEREK, L., LEMM, M., and SCHLAG, P.M. (2001). Nonviral in vivo gene delivery into tumors using a novel low volume jet-injection technology. Gene Ther. 8, 173-180.
-
(2001)
Gene Ther.
, vol.8
, pp. 173-180
-
-
Walther, W.1
Stein, U.2
Fichtner, I.3
Malcherek, L.4
Lemm, M.5
Schlag, P.M.6
-
38
-
-
1142267655
-
Glypican-3 is involved in cellular protection against mitoxantrone in gastric carcinoma cells
-
WICHERT, A., STEGE, A., MIDORIKAWA, Y., HOLM, P.S., and LAGE, H. (2004). Glypican-3 is involved in cellular protection against mitoxantrone in gastric carcinoma cells. Oncogene 23, 945-955.
-
(2004)
Oncogene
, vol.23
, pp. 945-955
-
-
Wichert, A.1
Stege, A.2
Midorikawa, Y.3
Holm, P.S.4
Lage, H.5
-
39
-
-
0034795256
-
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
-
ZHOU, S., SCHUETZ, J.D., BUNTING, K.D., COLAPIETRO, A.M., SAMPATH, J., MORRIS, J.J., LAGUTINA, I., GROSVELD, G.G., OSAWA, M., NAKAUCHI, H., and SORRENTINO, B.P. (2001). The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat. Med. 7, 1028-1034.
-
(2001)
Nat. Med.
, vol.7
, pp. 1028-1034
-
-
Zhou, S.1
Schuetz, J.D.2
Bunting, K.D.3
Colapietro, A.M.4
Sampath, J.5
Morris, J.J.6
Lagutina, I.7
Grosveld, G.G.8
Osawa, M.9
Nakauchi, H.10
Sorrentino, B.P.11
|