Strongly amphiphilic photosensitizers are not substrates of the cancer stem cell marker ABCG2 and provides specific and efficient light-triggered drug delivery of an EGFR-targeted cytotoxic drug

Journal of Controlled Release

Volumn 159, Issue 2, 2012, Pages 197-203

  Selbo, Pål Kristian ^a,b   Weyergang, Anette ^a   Eng, Marius Strombo ^a   Bostad, Monica ^a   Mælandsmo, Gunhild M ^a   Hogset, Anders ^a,b   Berg, Kristian ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b PCI Biotech AS   (Norway)

Author keywords

ABCG2; Cancer stem cells; Drug delivery; EGFR; MDR; Photochemical internalization

Indexed keywords

ABCG2; CANCER STEM CELLS; EGFR; MDR; PHOTOCHEMICAL INTERNALIZATION;

CELL CULTURE; CYTOTOXICITY; DISEASES; DRUG DELIVERY; INTERFACES (COMPUTER); PHOTODYNAMIC THERAPY; STEM CELLS; SUBSTRATES;

PHOTOSENSITIZERS;

BREAST CANCER RESISTANCE PROTEIN; FUMITREMORGIN C; HOE 33342; PHEOPHORBIDE; SAPORIN; TETRAPHENYLPORPHINESULFONIC ACID; VASCULOTROPIN RECEPTOR;

ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER STEM CELL; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; GLIOBLASTOMA; HUMAN; HUMAN CELL; PHOTOCHEMICAL INTERNALIZATION; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL;

ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG CARRIERS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ENDOCYTOSIS; FLOW CYTOMETRY; HUMANS; LIGHT; MICROSCOPY, FLUORESCENCE; MOLECULAR STRUCTURE; NEOPLASM PROTEINS; PHOTOSENSITIZING AGENTS; PORPHYRINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SUBSTRATE SPECIFICITY; SURFACE-ACTIVE AGENTS;

EID: 84861097763     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.02.003     Document Type: Article

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