-
1
-
-
84892965801
-
Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: A systematic review and meta-analysis
-
Wong WL, Su X, Li X, et al. Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis. Lancet Glob Health 2014;2:e106-16.
-
(2014)
Lancet Glob Health
, vol.2
, pp. e106-e116
-
-
Wong, W.L.1
Su, X.2
Li, X.3
-
4
-
-
33749440219
-
Age-related macular degeneration
-
de Jong PT. Age-related macular degeneration. N Engl J Med 2006;355:1474-85.
-
(2006)
N Engl J Med
, vol.355
, pp. 1474-1485
-
-
De Jong, P.T.1
-
5
-
-
84899959975
-
Geographic atrophy: Clinical features and potential therapeutic approaches
-
Holz FG, Strauss EC, Schmitz-Valckenberg S, et al. Geographic atrophy: clinical features and potential therapeutic approaches. Ophthalmology 2014;121:1079-91.
-
(2014)
Ophthalmology
, vol.121
, pp. 1079-1091
-
-
Holz, F.G.1
Strauss, E.C.2
Schmitz-Valckenberg, S.3
-
7
-
-
33749451356
-
Ranibizumab versus verteporfin for neovascular age-related macular degeneration
-
Brown DM, Kaiser PK, Michels M, et al. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N Engl J Med 2006;355:1432-44.
-
(2006)
N Engl J Med
, vol.355
, pp. 1432-1444
-
-
Brown, D.M.1
Kaiser, P.K.2
Michels, M.3
-
8
-
-
33749445317
-
Ranibizumab for neovascular age-related macular degeneration
-
Rosenfeld PJ, Brown DM, Heier JS, et al. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med 2006;355:1419-31.
-
(2006)
N Engl J Med
, vol.355
, pp. 1419-1431
-
-
Rosenfeld, P.J.1
Brown, D.M.2
Heier, J.S.3
-
9
-
-
84872711163
-
Antivascular endothelial growth factor agents for neovascular age-related macular degeneration
-
Zampros I, Praidou A, Brazitikos P, et al. Antivascular endothelial growth factor agents for neovascular age-related macular degeneration. J Ophthalmol 2012;2012:319728.
-
(2012)
J Ophthalmol
, vol.2012
, pp. 319728
-
-
Zampros, I.1
Praidou, A.2
Brazitikos, P.3
-
10
-
-
84877734641
-
Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: The Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial
-
Age-Related Eye Disease Study 2 Research Group. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. JAMA 2013;309:2005-15.
-
(2013)
JAMA
, vol.309
, pp. 2005-2015
-
-
-
11
-
-
0034800655
-
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
-
Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol 2001;119:1417-36.
-
(2001)
Arch Ophthalmol
, vol.119
, pp. 1417-1436
-
-
-
12
-
-
0033795036
-
The role of oxidative stress in the pathogenesis of age-related macular degeneration
-
Beatty S, Koh H-H, Phil M, et al. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 2000;45:115-34.
-
(2000)
Surv Ophthalmol
, vol.45
, pp. 115-134
-
-
Beatty, S.1
Koh, H.-H.2
Phil, M.3
-
13
-
-
79952112401
-
Oxidation and age-related macular degeneration: Insights from molecular biology
-
Khandhadia S, Lotery A. Oxidation and age-related macular degeneration: insights from molecular biology. Expert Rev Mol Med 2010;12:e34.
-
(2010)
Expert Rev Mol Med
, vol.12
, pp. e34
-
-
Khandhadia, S.1
Lotery, A.2
-
14
-
-
84891760717
-
Induction of necrotic cell death by oxidative stress in retinal pigment epithelial cells
-
Hanus J, Zhang H, Wang Z, et al. Induction of necrotic cell death by oxidative stress in retinal pigment epithelial cells. Cell Death Dis 2013;4:e965.
-
(2013)
Cell Death Dis
, vol.4
, pp. e965
-
-
Hanus, J.1
Zhang, H.2
Wang, Z.3
-
15
-
-
43449101556
-
Retinal dysfunction and progressive retinal cell death in SOD1-deficient mice
-
Hashizume K, Hirasawa M, Imamura Y, et al. Retinal dysfunction and progressive retinal cell death in SOD1-deficient mice. Am J Pathol 2008;172:1325-31.
-
(2008)
Am J Pathol
, vol.172
, pp. 1325-1331
-
-
Hashizume, K.1
Hirasawa, M.2
Imamura, Y.3
-
16
-
-
79955765832
-
Age-related retinopathy in NRF2-deficient mice
-
Zhao Z, Chen Y, Wang J, et al. Age-related retinopathy in NRF2-deficient mice. PLoS ONE 2011;6:e19456.
-
(2011)
PLoS ONE
, vol.6
, pp. e19456
-
-
Zhao, Z.1
Chen, Y.2
Wang, J.3
-
17
-
-
59849104241
-
Molecular pathology of age-related macular degeneration
-
Ding X, Patel M, Chan CC. Molecular pathology of age-related macular degeneration. Prog Retin Eye Res 2009;28:1-18.
-
(2009)
Prog Retin Eye Res
, vol.28
, pp. 1-18
-
-
Ding, X.1
Patel, M.2
Chan, C.C.3
-
18
-
-
84872711994
-
Next-generation therapeutic solutions for age-related macular degeneration
-
Cunnusamy K, Ufret-Vincenty R, Wang S. Next-generation therapeutic solutions for age-related macular degeneration. Pharm Pat Anal 2012;1:193-206.
-
(2012)
Pharm Pat Anal
, vol.1
, pp. 193-206
-
-
Cunnusamy, K.1
Ufret-Vincenty, R.2
Wang, S.3
-
19
-
-
79957619481
-
Inflammation and age-related macular degeneration (AMD)
-
Telander DG. Inflammation and age-related macular degeneration (AMD). Semin Ophthalmol 2011;26:192-7.
-
(2011)
Semin Ophthalmol
, vol.26
, pp. 192-197
-
-
Telander, D.G.1
-
20
-
-
84856985610
-
Lipids, lipoproteins, and age-related macular degeneration
-
Ebrahimi KB, Handa JT. Lipids, lipoproteins, and age-related macular degeneration. J Lipids 2011;2011:802059.
-
(2011)
J Lipids
, vol.2011
, pp. 802059
-
-
Ebrahimi, K.B.1
Handa, J.T.2
-
21
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
Klein RJ, Zeiss C, Chew EY, et al. Complement factor H polymorphism in age-related macular degeneration. Science 2005;308:385-9.
-
(2005)
Science
, vol.308
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
-
22
-
-
17244379811
-
Complement factor H polymorphism and age-related macular degeneration
-
Edwards AO, Ritter R III, Abel KJ, et al. Complement factor H polymorphism and age-related macular degeneration. Science 2005;308:421-4.
-
(2005)
Science
, vol.308
, pp. 421-424
-
-
Edwards, A.O.1
Ritter, R.2
Abel, K.J.3
-
23
-
-
20244388812
-
Complement factor H variant increases the risk of age-related macular degeneration
-
Haines JL, Hauser MA, Schmidt S, et al. Complement factor H variant increases the risk of age-related macular degeneration. Science 2005;308:419-21.
-
(2005)
Science
, vol.308
, pp. 419-421
-
-
Haines, J.L.1
Ma, H.2
Schmidt, S.3
-
24
-
-
33645419787
-
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
-
Gold B, Merriam JE, Zernant J, et al. Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat Genet 2006;38:458-62.
-
(2006)
Nat Genet
, vol.38
, pp. 458-462
-
-
Gold, B.1
Merriam, J.E.2
Zernant, J.3
-
25
-
-
34547764305
-
Complement C3 variant and the risk of age-related macular degeneration
-
Yates JR, Sepp T, Matharu BK, et al. Complement C3 variant and the risk of age-related macular degeneration. N Engl J Med 2007;357:553-61.
-
(2007)
N Engl J Med
, vol.357
, pp. 553-561
-
-
Yates, J.R.1
Sepp, T.2
Matharu, B.K.3
-
27
-
-
84878589219
-
Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome
-
Legendre CM, Licht C, Muus P, et al. Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome. N Engl J Med 2013;368:2169-81.
-
(2013)
N Engl J Med
, vol.368
, pp. 2169-2181
-
-
Legendre, C.M.1
Licht, C.2
Muus, P.3
-
28
-
-
84896695485
-
Systemic complement inhibition with eculizumab for geographic atrophy in age-related macular degeneration: The COMPLETE study
-
Yehoshua Z, de Amorim Garcia Filho CA, Nunes RP, et al. Systemic complement inhibition with eculizumab for geographic atrophy in age-related macular degeneration: the COMPLETE study. Ophthalmology 2014;121:693-701.
-
(2014)
Ophthalmology
, vol.121
, pp. 693-701
-
-
Yehoshua, Z.1
De Amorim Garcia Filho, C.A.2
Nunes, R.P.3
-
29
-
-
84902317208
-
Change in drusen volume as a novel clinical trial endpoint for the study of complement inhibition in age-related macular degeneration
-
Garcia Filho CA, Yehoshua Z, Gregori G, et al. Change in drusen volume as a novel clinical trial endpoint for the study of complement inhibition in age-related macular degeneration. Ophthalmic Surg Lasers Imaging Retina 2014;45:18-31.
-
(2014)
Ophthalmic Surg Lasers Imaging Retina
, vol.45
, pp. 18-31
-
-
Garcia Filho, C.A.1
Yehoshua, Z.2
Gregori, G.3
-
30
-
-
84952054020
-
-
http://www.ophthotech.com/product-candidates/
-
-
-
-
31
-
-
84951990296
-
-
http://www.roche.com/investors/updates/inv-update-2013-08-27.htm
-
-
-
-
32
-
-
0037623521
-
The Rapamune era of immunosuppression 2003: The journey from the laboratory to clinical transplantation
-
Camardo J. The Rapamune era of immunosuppression 2003: the journey from the laboratory to clinical transplantation. Transplantation proceedings 2003;35(3 Suppl):18s-24s.
-
(2003)
Transplantation Proceedings
, vol.35
, Issue.3
, pp. 18s-24s
-
-
Camardo, J.1
-
33
-
-
84859778293
-
MTOR signaling in growth control and disease
-
Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell 2012;149:274-93.
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
35
-
-
84876831911
-
Treatment of geographic atrophy with subconjunctival sirolimus: Results of a phase I/II clinical trial
-
Wong WT, Dresner S, Forooghian F, et al. Treatment of geographic atrophy with subconjunctival sirolimus: results of a phase I/II clinical trial. Invest Ophthalmol Vis Sci 2013;54:2941-50.
-
(2013)
Invest Ophthalmol Vis Sci
, vol.54
, pp. 2941-2950
-
-
Wong, W.T.1
Dresner, S.2
Forooghian, F.3
-
36
-
-
84908477655
-
Immunomodulation neuroprotection and remyelination- The fundamental therapeutic effects of glatiramer acetate: A critical review
-
Aharoni R. Immunomodulation neuroprotection and remyelination-the fundamental therapeutic effects of glatiramer acetate: a critical review. J Autoimmun 2014;54:81-92.
-
(2014)
J Autoimmun
, vol.54
, pp. 81-92
-
-
Aharoni, R.1
-
37
-
-
84858593367
-
Oxidative stress: The Achilles' heel of neurodegenerative diseases of the retina
-
Cai X, McGinnis JF. Oxidative stress: the Achilles' heel of neurodegenerative diseases of the retina. Front Biosci (Landmark Ed) 2012;17:1976-95.
-
(2012)
Front Biosci (Landmark Ed)
, vol.17
, pp. 1976-1995
-
-
Cai, X.1
McGinnis, J.F.2
-
38
-
-
38949185692
-
Oxidative damage-induced inflammation initiates age-related macular degeneration
-
Hollyfield JG, Bonilha VL, Rayborn ME, et al. Oxidative damage-induced inflammation initiates age-related macular degeneration. Nat Med 2008;14:194-8.
-
(2008)
Nat Med
, vol.14
, pp. 194-198
-
-
Hollyfield, J.G.1
Bonilha, V.L.2
Rayborn, M.E.3
-
39
-
-
34249802348
-
Oxidized phospholipids in the macula increase with age and in eyes with age-related macular degeneration
-
Suzuki M, Kamei M, Itabe H, et al. Oxidized phospholipids in the macula increase with age and in eyes with age-related macular degeneration. Mol Vis 2007;13:772-8.
-
(2007)
Mol Vis
, vol.13
, pp. 772-778
-
-
Suzuki, M.1
Kamei, M.2
Itabe, H.3
-
40
-
-
0037975774
-
Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas
-
Dentchev T, Milam AH, Lee VM, et al. Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas. Mol Vis 2003;9:184-90.
-
(2003)
Mol Vis
, vol.9
, pp. 184-190
-
-
Dentchev, T.1
Milam, A.H.2
Lee, V.M.3
-
41
-
-
70349255600
-
Change in area of geographic atrophy in the Age-Related Eye Disease Study: AREDS report number 26
-
Lindblad AS, Lloyd PC, Clemons TE, et al. Change in area of geographic atrophy in the Age-Related Eye Disease Study: AREDS report number 26. Arch Ophthalmol 2009;127:1168-74.
-
(2009)
Arch Ophthalmol
, vol.127
, pp. 1168-1174
-
-
Lindblad, A.S.1
Lloyd, P.C.2
Clemons, T.E.3
-
42
-
-
84881153208
-
Long-term effects of vitamins C and E, beta-carotene, and zinc on age-related macular degeneration: AREDS report no. 35
-
Chew EY, Clemons TE, Agrón E, et al. Long-term effects of vitamins C and E, beta-carotene, and zinc on age-related macular degeneration: AREDS report no. 35. Ophthalmology 2013;120:1604-11.e4.
-
(2013)
Ophthalmology
, vol.120
, pp. 1604-1604e4
-
-
Chew, E.Y.1
Clemons, T.E.2
Agrón, E.3
-
43
-
-
84894229056
-
Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression: AREDS2 report No
-
Chew EY, Clemons TE, Sangiovanni JP, et al. Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression: AREDS2 report No. 3. JAMA Ophthalmol 2014;132:142-9.
-
(2014)
3. JAMA Ophthalmol
, vol.132
, pp. 142-149
-
-
Chew, E.Y.1
Clemons, T.E.2
Sangiovanni, J.P.3
-
44
-
-
72749091971
-
{omega}-3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: AREDS report 30, a prospective cohort study from the Age-Related Eye Disease Study
-
Sangiovanni JP, Agron E, Meleth AD, et al. {omega}-3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: AREDS report 30, a prospective cohort study from the Age-Related Eye Disease Study. Am J Clin Nutr 2009;90:1601-7.
-
(2009)
Am J Clin Nutr
, vol.90
, pp. 1601-1607
-
-
Sangiovanni, J.P.1
Agron, E.2
Meleth, A.D.3
-
45
-
-
77953359470
-
Protection of retinal pigment epithelium by OT-551 and its metabolite TEMPOL-H against light-induced damage in rats
-
Tanito M, Li F, Anderson RE. Protection of retinal pigment epithelium by OT-551 and its metabolite TEMPOL-H against light-induced damage in rats. Exp Eye Res 2010;91:111-14.
-
(2010)
Exp Eye Res
, vol.91
, pp. 111-114
-
-
Tanito, M.1
Li, F.2
Anderson, R.E.3
-
46
-
-
79955056247
-
Treatment of geographic atrophy by the topical administration of OT-551: Results of a phase II clinical trial
-
Wong WT, Kam W, Cunningham D, et al. Treatment of geographic atrophy by the topical administration of OT-551: results of a phase II clinical trial. Ophthalmol Vis Sci 2010;51:6131-9.
-
(2010)
Ophthalmol Vis Sci
, vol.51
, pp. 6131-6139
-
-
Wong, W.T.1
Kam, W.2
Cunningham, D.3
-
47
-
-
84923617231
-
MRZ-99030-A novel modulator of Abeta aggregation: I-Mechanism of action (MoA) underlying the potential neuroprotective treatment of Alzheimer's disease, glaucoma and age-related macular degeneration (AMD)
-
Parsons CG, Ruitenberg M, Freitag CE, et al. MRZ-99030-A novel modulator of Abeta aggregation: I-Mechanism of action (MoA) underlying the potential neuroprotective treatment of Alzheimer's disease, glaucoma and age-related macular degeneration (AMD). Neuropharmacology 2015;92:158-69.
-
(2015)
Neuropharmacology
, vol.92
, pp. 158-169
-
-
Parsons, C.G.1
Ruitenberg, M.2
Freitag, C.E.3
-
48
-
-
84952023364
-
-
http://www.reviewofophthalmology.com/content/d/retinal-insider/c/44883/
-
-
-
-
49
-
-
0035069027
-
Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration
-
Holz FG, Bellman C, Staudt S, et al. Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration. Invest Ophthalmol Vis Sci 2001;42:1051-6.
-
(2001)
Invest Ophthalmol Vis Sci
, vol.42
, pp. 1051-1056
-
-
Holz, F.G.1
Bellman, C.2
Staudt, S.3
-
50
-
-
0344830731
-
Fundus autofluorescence in age-related macular disease imaged with a laser scanning ophthalmoscope
-
von Ruckmann A, Fitzke FW, Bird AC. Fundus autofluorescence in age-related macular disease imaged with a laser scanning ophthalmoscope. Invest Ophthalmol Vis Sci 1997;38:478-86.
-
(1997)
Invest Ophthalmol Vis Sci
, vol.38
, pp. 478-486
-
-
Von Ruckmann, A.1
Fitzke, F.W.2
Bird, A.C.3
-
51
-
-
0041342065
-
Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium
-
Schutt F, Bergmann M, Holz FG, et al. Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium. Invest Ophthalmol Vis Sci 2003;44:3663-8.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 3663-3668
-
-
Schutt, F.1
Bergmann, M.2
Holz, F.G.3
-
52
-
-
0029097328
-
Blue light-induced reactivity of retinal age pigment. in vitro generation of oxygen-reactive species
-
Rozanowska M, Jarvis-Evans J, Korytowski W, et al. Blue light-induced reactivity of retinal age pigment. In vitro generation of oxygen-reactive species. J Biol Chem 1995;270:18825-30.
-
(1995)
J Biol Chem
, vol.270
, pp. 18825-18830
-
-
Rozanowska, M.1
Jarvis-Evans, J.2
Korytowski, W.3
-
53
-
-
2142816581
-
Age-related changes in the photoreactivity of retinal lipofuscin granules: Role of chloroform-insoluble components
-
Rozanowska M, Pawlak A, Rozanowski B, et al. Age-related changes in the photoreactivity of retinal lipofuscin granules: role of chloroform-insoluble components. Invest Ophthalmol Vis Sci 2004;45:1052-60.
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 1052-1060
-
-
Rozanowska, M.1
Pawlak, A.2
Rozanowski, B.3
-
55
-
-
65549154386
-
The retinal oxysterol pathway: A unifying hypothesis for the cause of age-related macular degeneration
-
Javitt NB, Javitt JC. The retinal oxysterol pathway: a unifying hypothesis for the cause of age-related macular degeneration. Curr Opin Ophthalmol 2009;20:151-7.
-
(2009)
Curr Opin Ophthalmol
, vol.20
, pp. 151-157
-
-
Javitt, N.B.1
Javitt, J.C.2
-
56
-
-
33644795859
-
Reductions in serum Vitamin A arrest accumulation of toxic retinal fluorophores: A potential therapy for treatment of lipofuscin-based retinal diseases
-
Radu RA, Han Y, Bui TV, et al. Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: a potential therapy for treatment of lipofuscin-based retinal diseases. Invest Ophthalmol Vis Sci 2005;46:4393-401.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, pp. 4393-4401
-
-
Radu, R.A.1
Han, Y.2
Bui, T.V.3
-
57
-
-
84874950305
-
Investigation of oral fenretinide for treatment of geographic atrophy in age-related macular degeneration
-
Mata NL, Lichter JB, Vogel R, et al. Investigation of oral fenretinide for treatment of geographic atrophy in age-related macular degeneration. Retina (Philadelphia, Pa) 2013;33:498-507.
-
(2013)
Retina (Philadelphia, Pa)
, vol.33
, pp. 498-507
-
-
Mata, N.L.1
Lichter, J.B.2
Vogel, R.3
-
58
-
-
84855205404
-
Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator
-
Kubota R, Boman NL, David R, et al. Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator. Retina (Philadelphia, Pa) 2012;32:183-8.
-
(2012)
Retina (Philadelphia, Pa)
, vol.32
, pp. 183-188
-
-
Kubota, R.1
Boman, N.L.2
David, R.3
-
59
-
-
84894473858
-
Phase 1, dose-ranging study of emixustat hydrochloride (ACU-4429), a novel visual cycle modulator, in healthy volunteers
-
Kubota R, Al-Fayoumi S, Mallikaarjun S, et al. Phase 1, dose-ranging study of emixustat hydrochloride (ACU-4429), a novel visual cycle modulator, in healthy volunteers. Retina (Philadelphia, Pa) 2014;34:603-9.
-
(2014)
Retina (Philadelphia, Pa)
, vol.34
, pp. 603-609
-
-
Kubota, R.1
Al-Fayoumi, S.2
Mallikaarjun, S.3
-
60
-
-
84952029032
-
-
http://www.ffb.ca/research/research-news/Alkeus-Stargardt.html
-
-
-
-
61
-
-
84952003857
-
-
http://www.alkeuspharma.com/preclinical.html
-
-
-
-
63
-
-
84952019559
-
Is dry AMD treatable? A new ophthalmic solution may halt disease progression
-
Chiou G. Is dry AMD treatable? A new ophthalmic solution may halt disease progression. Retina Today 2012:69-79.
-
(2012)
Retina Today
, pp. 69-79
-
-
Chiou, G.1
-
64
-
-
84952045687
-
Effects of hydralazine on ocular blood flow and laser-induced choroidal neovascularization
-
Wei Jiang CG. Effects of hydralazine on ocular blood flow and laser-induced choroidal neovascularization. Int J Ophthalmol 2009;2:324-7.
-
(2009)
Int J Ophthalmol
, vol.2
, pp. 324-327
-
-
Wei Jiang, C.G.1
-
65
-
-
84952045687
-
Effects of hydralazine on ocular blood flow laser-induced choroidal neovascularization
-
Jiang W, Chiou GCY. Effects of hydralazine on ocular blood flow laser-induced choroidal neovascularization. Int J Ophthalmol 2009;2:324-7.
-
(2009)
Int J Ophthalmol
, vol.2
, pp. 324-327
-
-
Jiang, W.1
Chiou, G.C.Y.2
-
67
-
-
77949519072
-
Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat
-
Carr AJ, Vugler AA, Hikita ST, et al. Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat. PLoS ONE 2009;4:e8152.
-
(2009)
PLoS ONE
, vol.4
, pp. e8152
-
-
Carr, A.J.1
Vugler, A.A.2
Hikita, S.T.3
-
68
-
-
84861949600
-
Generation of retinal pigment epithelial cells from human embryonic stem cell-derived spherical neural masses
-
Cho MS, Kim SJ, Ku SY, et al. Generation of retinal pigment epithelial cells from human embryonic stem cell-derived spherical neural masses. Stem Cell Res 2012;9:101-9.
-
(2012)
Stem Cell Res
, vol.9
, pp. 101-109
-
-
Cho, M.S.1
Kim, S.J.2
Ku, S.Y.3
-
69
-
-
70350223975
-
Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells
-
Buchholz DE, Hikita ST, Rowland TJ, et al. Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. Stem Cells 2009;27:2427-34.
-
(2009)
Stem Cells
, vol.27
, pp. 2427-2434
-
-
De, B.1
Hikita, S.T.2
Rowland, T.J.3
-
70
-
-
79955396129
-
Human induced pluripotent stem-derived retinal pigment epithelium (RPE) cells exhibit ion transport, membrane potential, polarized vascular endothelial growth factor secretion, and gene expression pattern similar to native RPE
-
Kokkinaki M, Sahibzada N, Golestaneh N. Human induced pluripotent stem-derived retinal pigment epithelium (RPE) cells exhibit ion transport, membrane potential, polarized vascular endothelial growth factor secretion, and gene expression pattern similar to native RPE. Stem Cells 2011;29:825-35.
-
(2011)
Stem Cells
, vol.29
, pp. 825-835
-
-
Kokkinaki, M.1
Sahibzada, N.2
Golestaneh, N.3
-
71
-
-
79955936162
-
Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival
-
Zhu D, Deng X, Spee C, et al. Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival. Invest Ophthalmol Vis Sci 2011;52:1573-85.
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 1573-1585
-
-
Zhu, D.1
Deng, X.2
Spee, C.3
-
72
-
-
56349103166
-
Elucidating the phenomenon of HESC-derived RPE: Anatomy of cell genesis, expansion and retinal transplantation
-
Vugler A, Carr AJ, Lawrence J, et al. Elucidating the phenomenon of HESC-derived RPE: anatomy of cell genesis, expansion and retinal transplantation. Exp Neurol 2008;214:347-61.
-
(2008)
Exp Neurol
, vol.214
, pp. 347-361
-
-
Vugler, A.1
Carr, A.J.2
Lawrence, J.3
-
73
-
-
61449175932
-
Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay
-
Carr AJ, Vugler A, Lawrence J, et al. Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay. Mol Vis 2009;15:283-95.
-
(2009)
Mol Vis
, vol.15
, pp. 283-295
-
-
Carr, A.J.1
Vugler, A.2
Lawrence, J.3
-
74
-
-
84926452034
-
Recent advances towards the clinical application of stem cells for retinal regeneration
-
Becker S, Jayaram H, Limb GA. Recent advances towards the clinical application of stem cells for retinal regeneration. Cells 2012;1:851-73.
-
(2012)
Cells
, vol.1
, pp. 851-873
-
-
Becker, S.1
Jayaram, H.2
Limb, G.A.3
-
75
-
-
84923014395
-
Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: Follow-up of two open-label phase 1/2 studies
-
Schwartz SD, Regillo CD, Lam BL, et al. Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies. Lancet 2015;385:509-16.
-
(2015)
Lancet
, vol.385
, pp. 509-516
-
-
Schwartz, S.D.1
Regillo, C.D.2
Lam, B.L.3
-
76
-
-
0034687840
-
Direct isolation of human central nervous system stem cells
-
Uchida N, Buck DW, He D, et al. Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci USA 2000;97:14720-5.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 14720-14725
-
-
Uchida, N.1
Buck, D.W.2
He, D.3
-
77
-
-
84885663335
-
Phagocytosis of photoreceptor outer segments by transplanted human neural stem cells as a neuroprotective mechanism in retinal degeneration
-
Cuenca N, Fernandez-Sanchez L, McGill TJ, et al. Phagocytosis of photoreceptor outer segments by transplanted human neural stem cells as a neuroprotective mechanism in retinal degeneration. Invest Ophthalmol Vis Sci 2013;54: 6745-56.
-
(2013)
Invest Ophthalmol Vis Sci
, vol.54
, pp. 6745-6756
-
-
Cuenca, N.1
Fernandez-Sanchez, L.2
McGill, T.J.3
-
78
-
-
84862776670
-
Transplantation of human central nervous system stem cells-neuroprotection in retinal degeneration
-
McGill TJ, Cottam B, Lu B, et al. Transplantation of human central nervous system stem cells-neuroprotection in retinal degeneration. Eur J Neurosci 2012;35:468-77.
-
(2012)
Eur J Neurosci
, vol.35
, pp. 468-477
-
-
McGill, T.J.1
Cottam, B.2
Lu, B.3
-
79
-
-
84939864720
-
Polarization-sensitive optical coherence tomography and conventional retinal imaging strategies in assessing foveal integrity in geographic atrophy
-
Sayegh RG, Zotter S, Roberts PK, et al. Polarization-sensitive optical coherence tomography and conventional retinal imaging strategies in assessing foveal integrity in geographic atrophy. Invest Ophthalmol Vis Sci 2015;56:5246-55.
-
(2015)
Invest Ophthalmol Vis Sci
, vol.56
, pp. 5246-5255
-
-
Sayegh, R.G.1
Zotter, S.2
Roberts, P.K.3
-
80
-
-
84905102231
-
A systematic correlation of morphology and function using spectral domain optical coherence tomography and microperimetry in patients with geographic atrophy
-
Sayegh RG, Kiss CG, Simader C, et al. A systematic correlation of morphology and function using spectral domain optical coherence tomography and microperimetry in patients with geographic atrophy. Brit J Ophthalmol 2014;98: 1050-5.
-
(2014)
Brit J Ophthalmol
, vol.98
, pp. 1050-1055
-
-
Sayegh, R.G.1
Kiss, C.G.2
Simader, C.3
-
81
-
-
84908376132
-
A longitudinal comparison of spectral-domain optical coherence tomography and fundus autofluorescence in geographic atrophy
-
Simader C, Sayegh RG, Montuoro A, et al. A longitudinal comparison of spectral-domain optical coherence tomography and fundus autofluorescence in geographic atrophy. Am J Ophthalmol 2014;158:557-66.
-
(2014)
Am J Ophthalmol
, vol.158
, pp. 557-566
-
-
Simader, C.1
Sayegh, R.G.2
Montuoro, A.3
|