Phagocytosis of photoreceptor outer segments by transplanted human neural stem cells as a neuroprotective mechanism in retinal degeneration

Investigative Ophthalmology and Visual Science

Volumn 54, Issue 10, 2013, Pages 6745-6756

  Cuenca, Nicolás ^a   Fernández Sánchez, Laura ^a   McGill, Trevor J ^b   Lu, Bin ^c   Wang, Shaomei ^c   Lund, Raymond ^d   Huhn, Stephen ^e   Capela, Alexandra ^e  

^a UNIVERSITY OF ALICANTE   (Spain)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c CEDARS SINAI MEDICAL CENTER   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^e StemCells Inc   (United States)

Author keywords

Electron microscopy; Phagocytosis; Retinal degeneration; Synaptic contacts; Therapy; Transplant

Indexed keywords

CD133 ANTIGEN; CD24 ANTIGEN; CYCLOSPORIN A; DEXAMETHASONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ELECTRON MICROSCOPY; FLOW CYTOMETRY; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MICROSCOPY; NEURAL STEM CELL TRANSPLANTATION; NEUROPROTECTION; NONHUMAN; PHAGOCYTOSIS; PHAGOSOME; PHOTORECEPTOR OUTER SEGMENT; PRIORITY JOURNAL; RAT; RETINA DEGENERATION; RETINA INNER PLEXIFORM LAYER; SYNAPSE;

ELECTRON MICROSCOPY; PHAGOCYTOSIS; RETINAL DEGENERATION; SYNAPTIC CONTACTS; THERAPY; TRANSPLANT;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; NEURAL STEM CELLS; PHAGOCYTOSIS; RATS; RETINAL DEGENERATION; RETINAL PHOTORECEPTOR CELL OUTER SEGMENT; STEM CELL TRANSPLANTATION;

EID: 84885663335     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.13-12860     Document Type: Article

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