-
1
-
-
33745716919
-
Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease)
-
DOI 10.1136/jmg.2005.038315
-
Abrera-Abeleda MA, Nishimura C, Smith JL, Sethi S, McRae JL, Murphy BF, Silvestri G, Skerka C, Jozsi M, Zipfel PF, Hageman GS, Smith RJ (2006) Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease). J Med Genet 43(7):582-589 (Pubitemid 44048765)
-
(2006)
Journal of Medical Genetics
, vol.43
, Issue.7
, pp. 582-589
-
-
Abrera-Abeleda, M.A.1
Nishimura, C.2
Smith, J.L.H.3
Sethi, S.4
McRae, J.L.5
Murphy, B.F.6
Silvestri, G.7
Skerka, C.8
Jozsi, M.9
Zipfel, P.F.10
Hageman, G.S.11
Smith, R.J.H.12
-
2
-
-
0036741098
-
A role for local inflammation in the formation of drusen in the aging eye
-
Anderson DH, Mullins RF, Hageman GS, Johnson LV (2002) A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol 134(3):411-431
-
(2002)
Am J Ophthalmol
, vol.134
, Issue.3
, pp. 411-431
-
-
Anderson, D.H.1
Mullins, R.F.2
Hageman, G.S.3
Johnson, L.V.4
-
3
-
-
23944468114
-
Membranoproliferative glomerulonephritis type II (dense deposit disease): An update
-
DOI 10.1681/ASN.2005010078
-
Appel GB, Cook HT, Hageman G, Jennette JC, Kashgarian M, Kirschfink M, Lambris JD, Lanning L, Lutz HU, Meri S, Rose NR, Salant DJ, Sethi S, Smith RJ, Smoyer W, Tully HF, Tully SP, Walker P, Welsh M, Wurzner R, Zipfel PF (2005) Membranoproliferative glomerulonephritis type II (dense deposit disease): an update. J Am Soc Nephrol 16(5):1392-1403 (Pubitemid 41716523)
-
(2005)
Journal of the American Society of Nephrology
, vol.16
, Issue.5
, pp. 1392-1403
-
-
Appel, G.B.1
Cook, H.T.2
Hageman, G.3
Jennette, J.C.4
Kashgarian, M.5
Kirschfink, M.6
Lambris, J.D.7
Lanning, L.8
Lutz, H.U.9
Meri, S.10
Rose, N.R.11
Salant, D.J.12
Sethi, S.13
Smith, R.J.H.14
Smoyer, W.15
Tully, H.F.16
Tully, S.P.17
Walker, P.18
Welsh, M.19
Wurzner, R.20
Zipfel, P.F.21
more..
-
4
-
-
0028934221
-
An international classification and grading system for agerelated maculopathy and age-related macular degeneration. The international ARM epidemiological study group
-
Bird AC, Bressler NM, Bressler SB, Chisholm IH, Coscas G, Davis MD, de Jong PT, Klaver CC, Klein BE, Klein R et al (1995) An international classification and grading system for agerelated maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv Ophthalmol 39(5):367-374
-
(1995)
Surv Ophthalmol
, vol.39
, Issue.5
, pp. 367-374
-
-
Bird, A.C.1
Bressler, N.M.2
Bressler, S.B.3
Chisholm, I.H.4
Coscas, G.5
Davis, M.D.6
De Jong, P.T.7
Klaver, C.C.8
Klein, B.E.9
Klein, R.10
-
5
-
-
0025059813
-
Molecular basis of polymorphisms of human complement component C3
-
Botto M, Fong KY, So AK, Koch C, Walport MJ (1990) Molecular basis of polymorphisms of human complement component C3. J Exp Med 172(4):1011-1017 (Pubitemid 20343199)
-
(1990)
Journal of Experimental Medicine
, vol.172
, Issue.4
, pp. 1011-1017
-
-
Botto, M.1
Yong Fong, K.2
So, A.K.3
Koch, C.4
Walport, M.J.5
-
6
-
-
33646486869
-
Influence of donor C3 allotype on late renal-transplantation outcome
-
Brown KM, Kondeatis E, Vaughan RW, Kon SP, Farmer CK, Taylor JD, He X, Johnston A, Horsfield C, Janssen BJ, Gros P, Zhou W, Sacks SH, Sheerin NS (2006) Influence of donor C3 allotype on late renal-transplantation outcome. N Engl J Med 354(19):2014-2023
-
(2006)
N Engl J Med
, vol.354
, Issue.19
, pp. 2014-2023
-
-
Brown, K.M.1
Kondeatis, E.2
Vaughan, R.W.3
Kon, S.P.4
Farmer, C.K.5
Taylor, J.D.6
He, X.7
Johnston, A.8
Horsfield, C.9
Janssen, B.J.10
Gros, P.11
Zhou, W.12
Sacks, S.H.13
Sheerin, N.S.14
-
7
-
-
51649092992
-
C-reactive protein and coronary heart disease: A critical review
-
Casas JP, Shah T, Hingorani AD, Danesh J, Pepys MB (2008) C-reactive protein and coronary heart disease: a critical review. J Intern Med 264(4):295-314
-
(2008)
J Intern Med
, vol.264
, Issue.4
, pp. 295-314
-
-
Casas, J.P.1
Shah, T.2
Hingorani, A.D.3
Danesh, J.4
Pepys, M.B.5
-
8
-
-
33845953595
-
Association of complement factor H polymorphisms with exudative age-related macular degeneration
-
Chen LJ, Liu DT, Tam PO, Chan WM, Liu K, Chong KK, Lam DS, Pang CP (2006) Association of complement factor H polymorphisms with exudative age-related macular degeneration. Mol Vis 12:1536-1542 (Pubitemid 46029772)
-
(2006)
Molecular Vision
, vol.12
, pp. 1536-1542
-
-
Chen, L.J.1
Liu, D.T.L.2
Tam, P.O.S.3
Chan, W.M.4
Liu, K.5
Chong, K.K.L.6
Lam, D.S.C.7
Pang, C.P.8
-
9
-
-
33747700932
-
His-384 allotypic variant of factor H associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form
-
DOI 10.1074/jbc.M605083200
-
Clark SJ, Higman VA, Mulloy B, Perkins SJ, Lea SM, Sim RB, Day AJ (2006) His-384 allotypic variant of factor H associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form. J Biol Chem 281(34):24713-24720 (Pubitemid 44274245)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.34
, pp. 24713-24720
-
-
Clark, S.J.1
Higman, V.A.2
Mulloy, B.3
Perkins, S.J.4
Lea, S.M.5
Sim, R.B.6
Day, A.J.7
-
10
-
-
1842530296
-
Causes and Prevalence of Visual Impairment among Adults in the United States
-
DOI 10.1001/archopht.122.4.477
-
Congdon N, O'Colmain B, Klaver CC, Klein R, Munoz B, Friedman DS, Kempen J, Taylor HR, Mitchell P (2004) Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol 122(4):477-485 (Pubitemid 38456282)
-
(2004)
Archives of Ophthalmology
, vol.122
, Issue.4
, pp. 477-485
-
-
Congdon, N.1
-
11
-
-
11144258543
-
Drusen proteome analysis: An approach to the etiology of age-related macular degeneration
-
DOI 10.1073/pnas.222551899
-
Crabb JW, Miyagi M, Gu X, Shadrach K, West KA, Sakaguchi H, Kamei M, Hasan A, Yan L, Rayborn ME, Salomon RG, Hollyfield JG (2002) Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. Proc Natl Acad Sci U S A 99(23):14682-14687 (Pubitemid 35334544)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.23
, pp. 14682-14687
-
-
Crabb, J.W.1
Miyagi, M.2
Gu, X.3
Shadrach, K.4
West, K.A.5
Sakaguchi, H.6
Kamei, M.7
Hasan, A.8
Yan, L.9
Rayborn, M.E.10
Salomon, R.G.11
Hollyfield, J.G.12
-
12
-
-
33749440219
-
Age-related macular degeneration
-
DOI 10.1056/NEJMra062326
-
de Jong PT (2006) Age-related macular degeneration. N Engl J Med 355(14):1474-1485 (Pubitemid 44511562)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.14
, pp. 1474-1485
-
-
De Jong, P.T.V.M.1
-
13
-
-
33751011889
-
HTRA1 promoter polymorphism in wet age-related macular degeneration
-
DOI 10.1126/science.1133807
-
Dewan A, Liu M, Hartman S, Zhang SS, Liu DT, Zhao C, Tam PO, Chan WM, Lam DS, Snyder M, Barnstable C, Pang CP, Hoh J (2006) HTRA1 promoter polymorphism in wet age-related macular degeneration. Science 314(5801):989-992 (Pubitemid 44749943)
-
(2006)
Science
, vol.314
, Issue.5801
, pp. 989-992
-
-
DeWan, A.1
Liu, M.2
Hartman, S.3
Zhang, S.S.-M.4
Liu, D.T.L.5
Zhao, C.6
Tam, P.O.S.7
Chan, W.M.8
Lam, D.S.C.9
Snyder, M.10
Barnstable, C.11
Pang, C.P.12
Hoh, J.13
-
14
-
-
33144459399
-
The role of inflammation in the pathogenesis of age-related macular degeneration
-
DOI 10.1016/j.survophthal.2005.12.001, PII S0039625705002067
-
Donoso LA, Kim D, Frost A, Callahan A, Hageman G (2006) The role of inflammation in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 51(2):137-152 (Pubitemid 43269939)
-
(2006)
Survey of Ophthalmology
, vol.51
, Issue.2
, pp. 137-152
-
-
Donoso, L.A.1
Kim, D.2
Frost, A.3
Callahan, A.4
Hageman, G.5
-
15
-
-
17244379811
-
Complement factor H polymorphism and age-related macular degeneration
-
DOI 10.1126/science.1110189
-
Edwards AO, Ritter R 3rd, Abel KJ, Manning A, Panhuysen C, Farrer LA (2005) Complement factor H polymorphism and age-related macular degeneration. Science 308(5720):421-424 (Pubitemid 40530082)
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 421-424
-
-
Edwards, A.O.1
Ritter III, R.2
Abel, K.J.3
Manning, A.4
Panhuysen, C.5
Farrer, L.A.6
-
16
-
-
11144354339
-
Prevalence of Age-Related Macular Degeneration in the United States
-
DOI 10.1001/archopht.122.4.564
-
Friedman DS, O'Colmain BJ, Munoz B, Tomany SC, McCarty C, de Jong PT, Nemesure B, Mitchell P, Kempen J (2004) Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 122(4):564-572 (Pubitemid 38456293)
-
(2004)
Archives of Ophthalmology
, vol.122
, Issue.4
, pp. 564-572
-
-
Friedman, D.S.1
O'Colmain, B.J.2
Munoz, B.3
Tomany, S.C.4
McCarty, C.5
DeJong, P.T.V.M.6
Nemesure, B.7
Mitchell, P.8
Kempen, J.9
Congdon, N.10
-
17
-
-
46249098503
-
Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA
-
DOI 10.1038/ng.170, PII NG170
-
Fritsche LG, Loenhardt T, Janssen A, Fisher SA, Rivera A, Keilhauer CN, Weber BH (2008) Agerelated macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA. Nat Genet 40(7):892-896 (Pubitemid 351913654)
-
(2008)
Nature Genetics
, vol.40
, Issue.7
, pp. 892-896
-
-
Fritsche, L.G.1
Loenhardt, T.2
Janssen, A.3
Fisher, S.A.4
Rivera, A.5
Keilhauer, C.N.6
Weber, B.H.F.7
-
18
-
-
0034613686
-
C-Reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an anti-inflammatory innate immune response: Implications for systemic autoimmunity
-
Gershov D, Kim S, Brot N, Elkon KB (2000) C-Reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an anti-inflammatory innate immune response: implications for systemic autoimmunity. J Exp Med 192(9):1353-1364
-
(2000)
J Exp Med
, vol.192
, Issue.9
, pp. 1353-1364
-
-
Gershov, D.1
Kim, S.2
Brot, N.3
Elkon, K.B.4
-
19
-
-
0038068044
-
A common site within factor H SCR 7 responsible for binding heparin, C-reactive protein and streptococcal M protein
-
DOI 10.1002/eji.200323541
-
Giannakis E, Jokiranta TS, Male DA, Ranganathan S, Ormsby RJ, Fischetti VA, Mold C, Gordon DL (2003) A common site within factor H SCR 7 responsible for binding heparin, C-reactive protein and streptococcal M protein. Eur J Immunol 33(4):962-969 (Pubitemid 36546684)
-
(2003)
European Journal of Immunology
, vol.33
, Issue.4
, pp. 962-969
-
-
Giannakis, E.1
Jokiranta, T.S.2
Male, D.A.3
Ranganathan, S.4
Ormsby, R.J.5
Fischetti, V.A.6
Mold, C.7
Gordon, D.L.8
-
20
-
-
33645419787
-
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
-
Gold B, Merriam JE, Zernant J, Hancox LS, Taiber AJ, Gehrs K, Cramer K, Neel J, Bergeron J, Barile GR, Smith RT, Hageman GS, Dean M, Allikmets R (2006) Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat Genet 38(4):458-462
-
(2006)
Nat Genet
, vol.38
, Issue.4
, pp. 458-462
-
-
Gold, B.1
Merriam, J.E.2
Zernant, J.3
Hancox, L.S.4
Taiber, A.J.5
Gehrs, K.6
Cramer, K.7
Neel, J.8
Bergeron, J.9
Barile, G.R.10
Smith, R.T.11
Hageman, G.S.12
Dean, M.13
Allikmets, R.14
-
21
-
-
33646581758
-
The role of human HtrA1 in arthritic disease
-
DOI 10.1074/jbc.M500361200
-
Grau S, Richards PJ, Kerr B, Hughes C, Caterson B, Williams AS, Junker U, Jones SA, Clausen T, Ehrmann M (2006) The role of human HtrA1 in arthritic disease. J Biol Chem 281(10):6124-6129 (Pubitemid 43847541)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.10
, pp. 6124-6129
-
-
Grau, S.1
Richards, P.J.2
Kerr, B.3
Hughes, C.4
Caterson, B.5
Williams, A.S.6
Junker, U.7
Jones, S.A.8
Clausen, T.9
Ehrmann, M.10
-
22
-
-
33847153137
-
Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: Characterization, ethnic distribution and evolutionary implications
-
DOI 10.1080/07853890601097030, PII 768564693
-
Hageman GS, Hancox LS, Taiber AJ, Gehrs KM, Anderson DH, Johnson LV, Radeke MJ, Kavanagh D, Richards A, Atkinson J, Meri S, Bergeron J, Zernant J, Merriam J, Gold B, Allikmets R, Dean M (2006) Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications. Ann Med 38(8):592-604 (Pubitemid 46292019)
-
(2006)
Annals of Medicine
, vol.38
, Issue.8
, pp. 592-604
-
-
Hageman, G.S.1
Hancox, L.S.2
Taiber, A.J.3
Gehrs, K.M.4
Anderson, D.H.5
Johnson, L.V.6
Radeke, M.J.7
Kavanagh, D.8
Richards, A.9
Atkinson, J.10
Meri, S.11
Bergeron, J.12
Zernant, J.13
Merriam, J.14
Gold, B.15
Allikmets, R.16
Dean, M.17
Hageman, J.18
Hoballah, J.19
Stockman, H.20
Immonen, I.21
Laine, M.22
Jarva, H.23
Jarvela, I.24
Seitsonen, S.25
Barile, G.26
Chang, S.27
Merriam, J.C.28
Smith, R.T.29
Yannuzzi, L.A.30
more..
-
23
-
-
0034832029
-
An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration
-
DOI 10.1016/S1350-9462(01)00010-6, PII S1350946201000106
-
Hageman GS, Luthert PJ, Victor Chong NH, Johnson LV, Anderson DH, Mullins RF (2001) An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res 20(6):705-732 (Pubitemid 32918285)
-
(2001)
Progress in Retinal and Eye Research
, vol.20
, Issue.6
, pp. 705-732
-
-
Hageman, G.S.1
Luthert, P.J.2
Victor Chong, N.H.3
Johnson, L.V.4
Anderson, D.H.5
Mullins, R.F.6
-
24
-
-
20244388812
-
Complement factor H variant increases the risk of age-related macular degeneration
-
DOI 10.1126/science.1110359
-
Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P, Spencer KL, Kwan SY, Noureddine M, Gilbert JR, Schnetz-Boutaud N, Agarwal A, Postel EA, Pericak-Vance MA (2005) Complement factor H variant increases the risk of age-related macular degeneration. Science 308(5720):419-421 (Pubitemid 40530081)
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 419-421
-
-
Haines, J.L.1
Hauser, M.A.2
Schmidt, S.3
Scott, W.K.4
Olson, L.M.5
Gallins, P.6
Spencer, K.L.7
Shu, Y.K.8
Noureddine, M.9
Gilbert, J.R.10
Schnetz-Boutaud, N.11
Agarwal, A.12
Postel, E.A.13
Pericak-Vance, M.A.14
-
25
-
-
0036211136
-
Genetic influence on early age-related maculopathy: A twin study
-
DOI 10.1016/S0161-6420(01)01049-1, PII S0161642001010491
-
Hammond CJ, Webster AR, Snieder H, Bird AC, Gilbert CE, Spector TD (2002) Genetic influence on early age-related maculopathy: a twin study. Ophthalmology 109(4):730-736 (Pubitemid 34272274)
-
(2002)
Ophthalmology
, vol.109
, Issue.4
, pp. 730-736
-
-
Hammond, C.J.1
Webster, A.R.2
Snieder, H.3
Bird, A.C.4
Gilbert, C.E.5
Spector, T.D.6
-
26
-
-
70349441306
-
Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation
-
Heinen S, Hartmann A, Lauer N, Wiehl U, Dahse HM, Schirmer S, Gropp K, Enghardt T, Wallich R, Halbich S, Mihlan M, Schlotzer-Schrehardt U, Zipfel PF, Skerka C (2009) Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation. Blood 114(12):2439-2447
-
(2009)
Blood
, vol.114
, Issue.12
, pp. 2439-2447
-
-
Heinen, S.1
Hartmann, A.2
Lauer, N.3
Wiehl, U.4
Dahse, H.M.5
Schirmer, S.6
Gropp, K.7
Enghardt, T.8
Wallich, R.9
Halbich, S.10
Mihlan, M.11
Schlotzer-Schrehardt, U.12
Zipfel, P.F.13
Skerka, C.14
-
27
-
-
0032742373
-
Functional properties of complement factor H-related proteins FHR-3 and FHR-4: Binding to the C3d region of C3b and differential regulation by heparin
-
Hellwage J, Jokiranta TS, Koistinen V, Vaarala O, Meri S, Zipfel PF (1999) Functional properties of complement factor H-related proteins FHR-3 and FHR-4: binding to the C3d region of C3b and differential regulation by heparin. FEBS Lett 462(3):345-352
-
(1999)
FEBS Lett
, vol.462
, Issue.3
, pp. 345-352
-
-
Hellwage, J.1
Jokiranta, T.S.2
Koistinen, V.3
Vaarala, O.4
Meri, S.5
Zipfel, P.F.6
-
28
-
-
34547102526
-
Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism
-
DOI 10.1074/jbc.M609636200
-
Herbert AP, Deakin JA, Schmidt CQ, Blaum BS, Egan C, Ferreira VP, Pangburn MK, Lyon M, Uhrin D, Barlow PN (2007) Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism. J Biol Chem 282(26):18960-18968 (Pubitemid 47100149)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.26
, pp. 18960-18968
-
-
Herbert, A.P.1
Deakin, J.A.2
Schmidt, C.Q.3
Blaum, B.S.4
Egan, C.5
Ferreira, V.P.6
Pangburn, M.K.7
Lyon, M.8
Uhrin, D.9
Barlow, P.N.10
-
29
-
-
44049086967
-
Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations
-
Hocking HG, Herbert AP, Kavanagh D, Soares DC, Ferreira VP, Pangburn MK, Uhrin D, Barlow PN (2008) Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations. J Biol Chem 283(14):9475-9487
-
(2008)
J Biol Chem
, vol.283
, Issue.14
, pp. 9475-9487
-
-
Hocking, H.G.1
Herbert, A.P.2
Kavanagh, D.3
Soares, D.C.4
Ferreira, V.P.5
Pangburn, M.K.6
Uhrin, D.7
Barlow, P.N.8
-
30
-
-
33749123246
-
A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration
-
DOI 10.1038/ng1890, PII NG1890
-
Hughes AE, Orr N, Esfandiary H, Diaz-Torres M, Goodship T, Chakravarthy U (2006) A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of agerelated macular degeneration. Nat Genet 38(10):1173-1177 (Pubitemid 44470363)
-
(2006)
Nature Genetics
, vol.38
, Issue.10
, pp. 1173-1177
-
-
Hughes, A.E.1
Orr, N.2
Esfandiary, H.3
Diaz-Torres, M.4
Goodship, T.5
Chakravarthy, U.6
-
31
-
-
23944465880
-
Susceptibility genes for age-related maculopathy on chromosome 10q26
-
DOI 10.1086/444437
-
Jakobsdottir J, Conley YP, Weeks DE, Mah TS, Ferrell RE, Gorin MB (2005) Susceptibility genes for age-related maculopathy on chromosome 10q26. Am J Hum Genet 77(3):389-407 (Pubitemid 41192646)
-
(2005)
American Journal of Human Genetics
, vol.77
, Issue.3
, pp. 389-407
-
-
Jakobsdottir, J.1
Conley, Y.P.2
Weeks, D.E.3
Mah, T.S.4
Ferrell, R.E.5
Gorin, M.B.6
-
32
-
-
33750859976
-
Structure of C3b reveals conformational changes that underlie complement activity
-
DOI 10.1038/nature05172, PII NATURE05172
-
Janssen BJ, Christodoulidou A, McCarthy A, Lambris JD, Gros P (2006) Structure of C3b reveals conformational changes that underlie complement activity. Nature 444(7116):213-216 (Pubitemid 44722062)
-
(2006)
Nature
, vol.444
, Issue.7116
, pp. 213-216
-
-
Janssen, B.J.C.1
Christodoulidou, A.2
McCarthy, A.3
Lambris, J.D.4
Gros, P.5
-
33
-
-
0033214998
-
Regulation of complement activation by C-reactive protein: Targeting the complement inhibitory activity of factor H by an interaction with short consensus repeat domains 7 and 8-11
-
Jarva H, Jokiranta TS, Hellwage J, Zipfel PF, Meri S (1999) Regulation of complement activation by C-reactive protein: targeting the complement inhibitory activity of factor H by an interaction with short consensus repeat domains 7 and 8-11. J Immunol 163(7):3957-3962 (Pubitemid 29450924)
-
(1999)
Journal of Immunology
, vol.163
, Issue.7
, pp. 3957-3962
-
-
Jarva, H.1
Jokiranta, T.S.2
Hellwage, J.3
Zipfel, P.F.4
Meri, S.5
-
34
-
-
33646681859
-
Effect of modified C-reactive protein on complement activation: A possible complement regulatory role of modified or monomeric C-reactive protein in atherosclerotic lesions
-
Ji SR, Wu Y, Potempa LA, Liang YH, Zhao J (2006a) Effect of modified C-reactive protein on complement activation: a possible complement regulatory role of modified or monomeric C-reactive protein in atherosclerotic lesions. Arterioscler Thromb Vasc Biol 26(4):935-941
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, Issue.4
, pp. 935-941
-
-
Ji, S.R.1
Wu, Y.2
Potempa, L.A.3
Liang, Y.H.4
Zhao, J.5
-
35
-
-
30944445008
-
Interactions of C-reactive protein with low-density lipoproteins: Implications for an active role of modified C-reactive protein in atherosclerosis
-
DOI 10.1016/j.biocel.2005.11.004, PII S1357272505003845
-
Ji SR, Wu Y, Potempa LA, Qiu Q, Zhao J (2006b) Interactions of C-reactive protein with lowdensity lipoproteins: implications for an active role of modified C-reactive protein in atherosclerosis. Int J Biochem Cell Biol 38(4):648-661 (Pubitemid 43117588)
-
(2006)
International Journal of Biochemistry and Cell Biology
, vol.38
, Issue.4
, pp. 648-661
-
-
Ji, S.-R.1
Wu, Y.2
Potempa, L.A.3
Qiu, Q.4
Zhao, J.5
-
36
-
-
33846001313
-
m
-
DOI 10.1096/fj.06-6722com
-
Ji SR, Wu Y, Zhu L, Potempa LA, Sheng FL, Lu W, Zhao J (2007) Cell membranes and liposomes dissociate C-reactive protein (CRP) to form a new, biologically active structural intermediate: mCRP(m). FASEB J 21(1):284-294 (Pubitemid 46052567)
-
(2007)
FASEB Journal
, vol.21
, Issue.1
, pp. 284-294
-
-
Ji, S.-R.1
Wu, Y.2
Zhu, L.3
Potempa, L.A.4
Sheng, F.-L.5
Lu, W.6
Zhao, J.7
-
37
-
-
0035699547
-
Complement activation and inflammatory processes in drusen formation and age related macular degeneration
-
DOI 10.1006/exer.2001.1094
-
Johnson LV, Leitner WP, Staples MK, Anderson DH (2001) Complement activation and inflammatory processes in Drusen formation and age related macular degeneration. Exp Eye Res 73(6):887-896 (Pubitemid 34112114)
-
(2001)
Experimental Eye Research
, vol.73
, Issue.6
, pp. 887-896
-
-
Johnson, L.V.1
Leitner, W.P.2
Staples, M.K.3
Anderson, D.H.4
-
38
-
-
33751243644
-
Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid
-
DOI 10.1073/pnas.0606234103
-
Johnson PT, Betts KE, Radeke MJ, Hageman GS, Anderson DH, Johnson LV (2006) Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid. Proc Natl Acad Sci U S A 103(46):17456-17461 (Pubitemid 44788990)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.46
, pp. 17456-17461
-
-
Johnson, P.T.1
Betts, K.E.2
Radeke, M.J.3
Hageman, G.S.4
Anderson, D.H.5
Johnson, L.V.6
-
39
-
-
47749126514
-
Factor H family proteins and human diseases
-
Jozsi M, Zipfel PF (2008) Factor H family proteins and human diseases. Trends Immunol 29(8):380-387
-
(2008)
Trends Immunol
, vol.29
, Issue.8
, pp. 380-387
-
-
Jozsi, M.1
Zipfel, P.F.2
-
40
-
-
36049042661
-
A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration
-
DOI 10.1073/pnas.0703933104
-
Kanda A, Chen W, Othman M, Branham KE, Brooks M, Khanna R, He S, Lyons R, Abecasis GR, Swaroop A (2007) A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. Proc Natl Acad Sci U S A 104(41):16227-16232 (Pubitemid 350099389)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.41
, pp. 16227-16232
-
-
Kanda, A.1
Chen, W.2
Othman, M.3
Branham, K.E.H.4
Brooks, M.5
Khanna, R.6
He, S.7
Lyons, R.8
Abecasis, G.R.9
Swaroop, A.10
-
41
-
-
1542297335
-
The epidemiology of age-related macular degeneration
-
DOI 10.1016/j.ajo.2003.11.069, PII S0002939403015095
-
Klein R, Peto T, Bird A, Vannewkirk MR (2004) The epidemiology of age-related macular degeneration. Am J Ophthalmol 137(3):486-495 (Pubitemid 38328641)
-
(2004)
American Journal of Ophthalmology
, vol.137
, Issue.3
, pp. 486-495
-
-
Klein, R.1
Peto, T.2
Bird, A.3
Vannewkirk, M.R.4
-
42
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
DOI 10.1126/science.1109557
-
Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferris FL, Ott J, Barnstable C, Hoh J (2005) Complement factor H polymorphism in age-related macular degeneration. Science 308(5720):385-389 (Pubitemid 40530070)
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
Tsai, J.-Y.4
Sackler, R.S.5
Haynes, C.6
Henning, A.K.7
SanGiovanni, J.P.8
Mane, S.M.9
Mayne, S.T.10
Bracken, M.B.11
Ferris, F.L.12
Ott, J.13
Barnstable, C.14
Hoh, J.15
-
43
-
-
0029850245
-
Mapping of the domains required for decay acceleration activity of the human factor H-like protein 1 and factor H
-
DOI 10.1002/eji.1830261017
-
Kuhn S, Zipfel PF (1996) Mapping of the domains required for decay acceleration activity of the human factor H-like protein 1 and factor H. Eur J Immunol 26(10):2383-2387 (Pubitemid 26340939)
-
(1996)
European Journal of Immunology
, vol.26
, Issue.10
, pp. 2383-2387
-
-
Kuhn, S.1
Zipfel, P.F.2
-
44
-
-
33947214392
-
Y402H polymorphism of complement factor H affects binding affinity to C-reactive protein
-
Laine M, Jarva H, Seitsonen S, Haapasalo K, Lehtinen MJ, Lindeman N, Anderson DH, Johnson PT, Jarvela I, Jokiranta TS, Hageman GS, Immonen I, Meri S (2007) Y402H polymorphismof complement factor H affects binding affinity to C-reactive protein. J Immunol 178(6):3831-3836 (Pubitemid 46417652)
-
(2007)
Journal of Immunology
, vol.178
, Issue.6
, pp. 3831-3836
-
-
Laine, M.1
Jarva, H.2
Seitsonen, S.3
Haapasalo, K.4
Lehtinen, M.J.5
Lindeman, N.6
Andersen, D.H.7
Johnson, P.T.8
Jarvela, I.9
Jokiranta, T.S.10
Hageman, G.S.11
Inanionen, I.12
Meri, S.13
-
45
-
-
33746551720
-
Apolipoprotein localization in isolated drusen and retinal apolipoprotein gene expression
-
DOI 10.1167/iovs.05-1446
-
Li CM, Clark ME, Chimento MF, Curcio CA (2006a) Apolipoprotein localization in isolated drusen and retinal apolipoprotein gene expression. Invest Ophthalmol Vis Sci 47(7):3119-3128 (Pubitemid 351639791)
-
(2006)
Investigative Ophthalmology and Visual Science
, vol.47
, Issue.7
, pp. 3119-3128
-
-
Li, C.-M.1
Clark, M.E.2
Chimento, M.F.3
Curcio, C.A.4
-
46
-
-
33748325757
-
CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration
-
DOI 10.1038/ng1871, PII NG1871
-
Li M, Atmaca-Sonmez P, Othman M, Branham KE, Khanna R, Wade MS, Li Y, Liang L, Zareparsi S, Swaroop A, Abecasis GR (2006b) CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration. Nat Genet 38(9):1049-1054 (Pubitemid 44325931)
-
(2006)
Nature Genetics
, vol.38
, Issue.9
, pp. 1049-1054
-
-
Li, M.1
Atmaca-Sonmez, P.2
Othman, M.3
Branham, K.E.H.4
Khanna, R.5
Wade, M.S.6
Li, Y.7
Liang, L.8
Zareparsi, S.9
Swaroop, A.10
Abecasis, G.R.11
-
47
-
-
0026044026
-
Allelic differences in hemolytic activity and protein concentration of BF molecules are found in association with particular HLA haplotypes
-
Lokki ML, Koskimies SA (1991) Allelic differences in hemolytic activity and protein concentration of BF molecules are found in association with particular HLA haplotypes. Immunogenetics 34(4):242-246
-
(1991)
Immunogenetics
, vol.34
, Issue.4
, pp. 242-246
-
-
Lokki, M.L.1
Koskimies, S.A.2
-
48
-
-
32044474231
-
CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD
-
Magnusson KP, Duan S, Sigurdsson H, Petursson H, Yang Z, Zhao Y, Bernstein PS, Ge J, Jonasson F, Stefansson E, Helgadottir G, Zabriskie NA, Jonsson T, Bjornsson A, Thorlacius T, Jonsson PV, Thorleifsson G, Kong A, Stefansson H, Zhang K, Stefansson K, Gulcher JR (2006) CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD. PLoS Med 3(1):e5
-
(2006)
PLoS Med
, vol.3
, Issue.1
-
-
Magnusson, K.P.1
Duan, S.2
Sigurdsson, H.3
Petursson, H.4
Yang, Z.5
Zhao, Y.6
Bernstein, P.S.7
Ge, J.8
Jonasson, F.9
Stefansson, E.10
Helgadottir, G.11
Zabriskie, N.A.12
Jonsson, T.13
Bjornsson, A.14
Thorlacius, T.15
Jonsson, P.V.16
Thorleifsson, G.17
Kong, A.18
Stefansson, H.19
Zhang, K.20
Stefansson, K.21
Gulcher, J.R.22
more..
-
49
-
-
70449724676
-
Monomeric CRP contributes to complement control in fluid phase and on cellular surfaces and increases phagocytosis by recruiting factor H
-
Mihlan M, Stippa S, Jozsi M, Zipfel PF (2009) Monomeric CRP contributes to complement control in fluid phase and on cellular surfaces and increases phagocytosis by recruiting factor H. Cell Death Differ 16:1630-1640
-
(2009)
Cell Death Differ
, vol.16
, pp. 1630-1640
-
-
Mihlan, M.1
Stippa, S.2
Jozsi, M.3
Zipfel, P.F.4
-
50
-
-
0024440772
-
Human complement factor H: An additional gene product of 43 kDa isolated from human plasma shows cofactor activity for the cleavage of the third component of complement
-
Misasi R, Huemer HP, Schwaeble W, Solder E, Larcher C, Dierich MP (1989) Human complement factor H: an additional gene product of 43 kDa isolated from human plasma shows cofactor activity for the cleavage of the third component of complement. Eur J Immunol 19(9):1765-1768 (Pubitemid 19243900)
-
(1989)
European Journal of Immunology
, vol.19
, Issue.9
, pp. 1765-1768
-
-
Misasi, R.1
Huemer, H.P.2
Schwaeble, W.3
Solder, E.4
Larcher, C.5
Dierich, M.P.6
-
51
-
-
33144488589
-
Drusen complement components C3a and C5a promote choroidal neovascularization
-
DOI 10.1073/pnas.0408835103
-
Nozaki M, Raisler BJ, Sakurai E, Sarma JV, Barnum SR, Lambris JD, Chen Y, Zhang K, Ambati BK, Baffi JZ, Ambati J (2006) Drusen complement components C3a and C5a promote choroidal neovascularization. Proc Natl Acad Sci U S A 103(7):2328-2333 (Pubitemid 43271669)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.7
, pp. 2328-2333
-
-
Nozaki, M.1
Raisler, B.J.2
Sakurai, E.3
Sarma, J.V.4
Barnum, S.R.5
Lambris, J.D.6
Chen, Y.7
Zhang, K.8
Ambati, B.K.9
Baffi, J.Z.10
Ambati, J.11
-
52
-
-
12144291128
-
HtrA1 serine protease inhibits signaling mediated by Tgfβ family proteins
-
DOI 10.1242/dev.00999
-
Oka C, Tsujimoto R, Kajikawa M, Koshiba-Takeuchi K, Ina J, Yano M, Tsuchiya A, Ueta Y, Soma A, Kanda H, Matsumoto M, Kawaichi M (2004) HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins. Development 131(5):1041-1053 (Pubitemid 38380458)
-
(2004)
Development
, vol.131
, Issue.5
, pp. 1041-1053
-
-
Oka, C.1
Tsujimoto, R.2
Kajikawa, M.3
Koshiba-Takeuchi, K.4
Ina, J.5
Yano, M.6
Tsuchiya, A.7
Ueta, Y.8
Soma, A.9
Kanda, H.10
Matsumoto, M.11
Kawaichi, M.12
-
53
-
-
33644676878
-
Complement factor H polymorphisms in Japanese population with age-related macular degeneration
-
Okamoto H, Umeda S, Obazawa M, Minami M, Noda T, Mizota A, Honda M, Tanaka M, Koyama R, Takagi I, Sakamoto Y, Saito Y, Miyake Y, Iwata T (2006) Complement factor H polymorphisms in Japanese population with age-related macular degeneration. Mol Vis 12:156-158 (Pubitemid 43329568)
-
(2006)
Molecular Vision
, vol.12
, pp. 156-158
-
-
Okamoto, H.1
Umeda, S.2
Obazawa, M.3
Minami, M.4
Noda, T.5
Mizota, A.6
Honda, M.7
Tanaka, M.8
Koyama, R.9
Takagi, I.10
Sakamoto, Y.11
Saito, Y.12
Miyake, Y.13
Iwata, T.14
-
54
-
-
44649138189
-
Functional and structural implications of the complement factor H Y402H polymorphism associated with age-related macular degeneration
-
Ormsby RJ, Ranganathan S, Tong JC, Griggs KM, Dimasi DP, Hewitt AW, Burdon KP, Craig JE, Hoh J, Gordon DL (2008) Functional and structural implications of the complement factor H Y402H polymorphism associated with age-related macular degeneration. Invest Ophthalmol Vis Sci 49(5):1763-1770
-
(2008)
Invest Ophthalmol Vis Sci
, vol.49
, Issue.5
, pp. 1763-1770
-
-
Ormsby, R.J.1
Ranganathan, S.2
Tong, J.C.3
Griggs, K.M.4
Dimasi, D.P.5
Hewitt, A.W.6
Burdon, K.P.7
Craig, J.E.8
Hoh, J.9
Gordon, D.L.10
-
55
-
-
0017704496
-
Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein β1H for cleavage of C3b and C4b in solution
-
Pangburn MK, Schreiber RD, Muller-Eberhard HJ (1977) Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution. J Exp Med 146(1):257-270 (Pubitemid 8139507)
-
(1977)
Journal of Experimental Medicine
, vol.146
, Issue.1
, pp. 257-270
-
-
Pangburn, M.K.1
Schreiber, R.D.2
Muller Eberhard, H.J.3
-
56
-
-
1942500141
-
2002 Global update of available data on visual impairment: A compilation of population-based prevalence studies
-
DOI 10.1076/opep.11.2.67.28158
-
Pascolini D, Mariotti SP, Pokharel GP, Pararajasegaram R, Etya'ale D, Negrel AD, Resnikoff S (2004) 2002 global update of available data on visual impairment: a compilation of populationbased prevalence studies. Ophthalmic Epidemiol 11(2):67-115 (Pubitemid 38530465)
-
(2004)
Ophthalmic Epidemiology
, vol.11
, Issue.2
, pp. 67-115
-
-
Pascolini, D.1
Mariotti, S.P.2
Pokharel, G.P.3
Pararajasegaram, R.4
Etya'ale, D.5
Negrel, A.-D.6
Resnikoff, S.7
-
58
-
-
0035121908
-
Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome
-
DOI 10.1086/318201
-
Perez-Caballero D, Gonzalez-Rubio C, Gallardo ME, Vera M, Lopez-Trascasa M, Rodriguez de Cordoba S, Sanchez-Corral P (2001) Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome. Am J Hum Genet 68(2):478-484 (Pubitemid 32147816)
-
(2001)
American Journal of Human Genetics
, vol.68
, Issue.2
, pp. 478-484
-
-
Perez-Caballero, D.1
Gonzalez-Rubio, C.2
Esther Gallardo, M.3
Vera, M.4
Lopez-Trascasa, M.5
Rodriguez De Cordoba, S.6
Sanchez-Corral, P.7
-
59
-
-
0023273456
-
Expression, detection and assay of a neoantigen (Neo-CRP) associated with a free, human C-reactive protein subunit
-
DOI 10.1016/0161-5890(87)90028-9
-
Potempa LA, Siegel JN, Fiedel BA, Potempa RT, Gewurz H (1987) Expression, detection and assay of a neoantigen (Neo-CRP) associated with a free, human C-reactive protein subunit. Mol Immunol 24(5):531-541 (Pubitemid 17062643)
-
(1987)
Molecular Immunology
, vol.24
, Issue.5
, pp. 531-541
-
-
Potempa, L.A.1
Siegel, J.N.2
Fiedel, B.A.3
-
60
-
-
34948910047
-
Structural basis for complement factor H-linked age-related macular degeneration
-
DOI 10.1084/jem.20071069
-
Prosser BE, Johnson S, Roversi P, Herbert AP, Blaum BS, Tyrrell J, Jowitt TA, Clark SJ, Tarelli E, Uhrin D, Barlow PN, Sim RB, Day AJ, Lea SM (2007) Structural basis for complement factor H linked age-related macular degeneration. J Exp Med 204(10):2277-2283 (Pubitemid 47529315)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.10
, pp. 2277-2283
-
-
Prosser, B.E.1
Johnson, S.2
Roversi, P.3
Herbert, A.P.4
Blaum, B.S.5
Tyrrell, J.6
Jowitt, T.A.7
Clark, S.J.8
Tarelli, E.9
Uhrin, D.10
Barlow, P.N.11
Sim, R.B.12
Day, A.J.13
Lea, S.M.14
-
61
-
-
27744462212
-
Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
-
DOI 10.1093/hmg/ddi353
-
Rivera A, Fisher SA, Fritsche LG, Keilhauer CN, Lichtner P, Meitinger T, Weber BH (2005) Hypothetical LOC387715 is a second major susceptibility gene for age-related maculardegeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet 14(21):3227-3236 (Pubitemid 41631297)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.21
, pp. 3227-3236
-
-
Rivera, A.1
Fisher, S.A.2
Fritsche, L.G.3
Keilhauer, C.N.4
Lichtner, P.5
Meitinger, T.6
Weber, B.H.F.7
-
62
-
-
2442433542
-
The human complement factor H: Functional roles, genetic variations and disease associations
-
DOI 10.1016/j.molimm.2004.02.005, PII S0161589004000501
-
Rodriguez de Cordoba S, Esparza-Gordillo J, Goicoechea de Jorge E, Lopez-Trascasa M, Sanchez-Corral P (2004) The human complement factor H: functional roles, genetic variations and disease associations. Mol Immunol 41(4):355-367 (Pubitemid 38639887)
-
(2004)
Molecular Immunology
, vol.41
, Issue.4
, pp. 355-367
-
-
Rodriguez De Cordoba, S.1
Esparza-Gordillo, J.2
Goicoechea De Jorge, E.3
Lopez-Trascasa, M.4
Sanchez-Corral, P.5
-
63
-
-
41149129090
-
Genetic markers and biomarkers for age-related macular degeneration
-
Ross RJ, Verma V, Rosenberg KI, Chan CC, Tuo J (2007) Genetic markers and biomarkers for age-related macular degeneration. Expert Rev Ophthalmol 2(3):443-457
-
(2007)
Expert Rev Ophthalmol
, vol.2
, Issue.3
, pp. 443-457
-
-
Ross, R.J.1
Verma, V.2
Rosenberg, K.I.3
Chan, C.C.4
Tuo, J.5
-
64
-
-
73949086785
-
Contribution of copy number variation in the regulation of complement activation locus to development of age-related macular degeneration
-
Schmid-Kubista KE, Tosakulwong N, Wu Y, Ryu E, Hecker LA, Baratz KH, Brown WL, Edwards AO (2009) Contribution of copy number variation in the regulation of complement activation locus to development of age-related macular degeneration. Invest Ophthalmol Vis Sci 50(11):5070-5079
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, Issue.11
, pp. 5070-5079
-
-
Schmid-Kubista, K.E.1
Tosakulwong, N.2
Wu, Y.3
Ryu, E.4
Hecker, L.A.5
Baratz, K.H.6
Brown, W.L.7
Edwards, A.O.8
-
65
-
-
49749150467
-
Systemic complement activation in age-related macular degeneration
-
Scholl HP, Charbel Issa P, Walier M, Janzer S, Pollok-Kopp B, Borncke F, Fritsche LG, Chong NV, Fimmers R, Wienker T, Holz FG, Weber BH, Oppermann M (2008) Systemic complement activation in age-related macular degeneration. PLoS ONE 3(7):e2593
-
(2008)
PLoS ONE
, vol.3
, Issue.7
-
-
Scholl, H.P.1
Charbel Issa, P.2
Walier, M.3
Janzer, S.4
Pollok-Kopp, B.5
Borncke, F.6
Fritsche, L.G.7
Chong, N.V.8
Fimmers, R.9
Wienker, T.10
Holz, F.G.11
Weber, B.H.12
Oppermann, M.13
-
67
-
-
14944364782
-
The US twin study of age-related macular degeneration: Relative roles of genetic and environmental influences
-
DOI 10.1001/archopht.123.3.321
-
Seddon JM, Cote J, Page WF, Aggen SH, Neale MC (2005) The US twin study of age-related macular degeneration: relative roles of genetic and environmental influences. Arch Ophthalmol 123(3):321-327 (Pubitemid 41007575)
-
(2005)
Archives of Ophthalmology
, vol.123
, Issue.3
, pp. 321-327
-
-
Seddon, J.M.1
Cote, J.2
Page, W.F.3
Aggen, S.H.4
Neale, M.C.5
-
68
-
-
33746382236
-
Analysis of variants in the complement factor H, the elongation of very long chain fatty acids-like 4 and the hemicentin 1 genes of age-related macular degeneration in the Finnish population
-
Seitsonen S, Lemmela S, Holopainen J, Tommila P, Ranta P, Kotamies A, Moilanen J, Palosaari T, Kaarniranta K, Meri S, Immonen I, Jarvela I (2006) Analysis of variants in the complement factor H, the elongation of very long chain fatty acids-like 4 and the hemicentin 1 genes of age-related macular degeneration in the Finnish population. Mol Vis 12:796-801 (Pubitemid 44111652)
-
(2006)
Molecular Vision
, vol.12
, pp. 796-801
-
-
Seitsonen, S.1
Lemmela, S.2
Holopainen, J.3
Tommila, P.4
Ranta, P.5
Kotamies, A.6
Moilanen, J.7
Palosaari, T.8
Kaarniranta, K.9
Meri, S.10
Immonen, I.11
Jarvela, I.12
-
69
-
-
33748474568
-
Polymorphism p.402Y>H in the complement factor H protein is a risk factor for age related macular degeneration in an Italian population
-
DOI 10.1136/bjo.2006.096487
-
Simonelli F, Frisso G, Testa F, di Fiore R, Vitale DF, Manitto MP, Brancato R, Rinaldi E, Sacchetti L (2006) Polymorphism p. 402Y > H in the complement factor H protein is a risk factor for age related macular degeneration in an Italian population. Br J Ophthalmol 90(9):1142-1145 (Pubitemid 44351146)
-
(2006)
British Journal of Ophthalmology
, vol.90
, Issue.9
, pp. 1142-1145
-
-
Simonelli, F.1
Frisso, G.2
Testa, F.3
Di Fiore, R.4
Vitale, D.F.5
Manitto, M.P.6
Brancato, R.7
Rinaldi, E.8
Sacchetti, L.9
-
70
-
-
34249740145
-
The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells
-
DOI 10.1074/jbc.M610256200
-
Sjoberg AP, Trouw LA, Clark SJ, Sjolander J, Heinegard D, Sim RB, Day AJ, Blom AM (2007) The factor H variant associated with age-related macular degeneration (His-384) and the nondisease- associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells. J Biol Chem 282(15):10894-10900 (Pubitemid 47100772)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.15
, pp. 10894-10900
-
-
Sjoberg, A.P.1
Trouw, L.A.2
Clark, S.J.3
Sjolander, J.4
Heinegard, D.5
Sim, R.B.6
Day, A.J.7
Blom, A.M.8
-
71
-
-
0026047501
-
Molecular cloning of a human serum protein structurally related to complement factor H
-
Skerka C, Horstmann RD, Zipfel PF (1991) Molecular cloning of a human serum protein structurally related to complement factor H. J Biol Chem 266(18):12015-12020 (Pubitemid 21907050)
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.18
, pp. 12015-12020
-
-
Skerka, C.1
Horstmann, R.D.2
Zipfel, P.F.3
-
72
-
-
34247573496
-
Defective complement control of Factor H (Y402H) and FHL-1 in age-related macular degeneration
-
DOI 10.1016/j.molimm.2007.02.012, PII S0161589007000855
-
Skerka C, Lauer N, Weinberger AA, Keilhauer CN, Suhnel J, Smith R, Schlotzer-Schrehardt U, Fritsche L, Heinen S, Hartmann A, Weber BH, Zipfel PF (2007) Defective complement control of factor H (Y402H) and FHL-1 in age-related macular degeneration. Mol Immunol 44(13):3398-3406 (Pubitemid 46678196)
-
(2007)
Molecular Immunology
, vol.44
, Issue.13
, pp. 3398-3406
-
-
Skerka, C.1
Lauer, N.2
Weinberger, A.A.W.A.3
Keilhauer, C.N.4
Suhnel, J.5
Smith, R.6
Schlotzer-Schrehardt, U.7
Fritsche, L.8
Heinen, S.9
Hartmann, A.10
Weber, B.H.F.11
Zipfel, P.F.12
-
73
-
-
57649230771
-
Complement factor H related proteins in immune diseases
-
Skerka C, Zipfel PF (2008) Complement factor H related proteins in immune diseases. Vaccine 26(Suppl 8):19-14
-
(2008)
Vaccine
, vol.26
, Issue.SUPPL. 8
, pp. 19-14
-
-
Skerka, C.1
Zipfel, P.F.2
-
74
-
-
29944437979
-
Y402H complement factor H polymorphism associated with exudative age-related macular degeneration in the French population
-
Souied EH, Leveziel N, Richard F, Dragon-Durey MA, Coscas G, Soubrane G, Benlian P, Fremeaux-Bacchi V (2005) Y402H complement factor H polymorphism associated with exudative age-related macular degeneration in the French population. Mol Vis 11:1135-1140 (Pubitemid 43040543)
-
(2005)
Molecular Vision
, vol.11
, pp. 1135-1140
-
-
Souied, E.H.1
Leveziel, N.2
Richard, F.3
Dragon-Durey, M.-A.4
Coscas, G.5
Soubrane, G.6
Benlian, P.7
Fremeaux-Bacchi, V.8
-
75
-
-
41149171882
-
Deletion of CFHR3 and CFHR1 genes in age-related macular degeneration
-
DOI 10.1093/hmg/ddm369
-
Spencer KL, Hauser MA, Olson LM, Schmidt S, Scott WK, Gallins P, Agarwal A, Postel EA, Pericak-Vance MA, Haines JL (2008a) Deletion of CFHR3 and CFHR1 genes in age-related macular degeneration. Hum Mol Genet 17(7):971-977 (Pubitemid 351426031)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.7
, pp. 971-977
-
-
Spencer, K.L.1
Hauser, M.A.2
Olson, L.M.3
Schmidt, S.4
Scott, W.K.5
Gallins, P.6
Agarwal, A.7
Postel, E.A.8
Pericak-Vance, M.A.9
Haines, J.L.10
-
76
-
-
44849088405
-
C3 R102G polymorphism increases risk of age-related macular degeneration
-
DOI 10.1093/hmg/ddn075
-
Spencer KL, Olson LM, Anderson BM, Schnetz-Boutaud N, Scott WK, Gallins P, Agarwal A, Postel EA, Pericak-Vance MA, Haines JL (2008b) C3 R102G polymorphism increases risk of age-related macular degeneration. Hum Mol Genet 17(12):1821-1824 (Pubitemid 351791509)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.12
, pp. 1821-1824
-
-
Spencer, K.L.1
Olson, L.M.2
Anderson, B.M.3
Schnetz-Boutaud, N.4
Scott, W.K.5
Gallins, P.6
Agarwal, A.7
Postel, E.A.8
Pericak-Vance, M.A.9
Haines, J.L.10
-
77
-
-
31144460785
-
The central role of the alternative complement pathway in human disease
-
Thurman JM, Holers VM (2006) The central role of the alternative complement pathway in human disease. J Immunol 176(3):1305-1310 (Pubitemid 43134269)
-
(2006)
Journal of Immunology
, vol.176
, Issue.3
, pp. 1305-1310
-
-
Thurman, J.M.1
Holers, V.M.2
-
78
-
-
69449090499
-
The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity
-
Tortajada A, Montes T, Martinez-Barricarte R, Morgan BP, Harris CL, de Cordoba SR (2009) The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity. Hum Mol Genet 18(18):3452-3461
-
(2009)
Hum Mol Genet
, vol.18
, Issue.18
, pp. 3452-3461
-
-
Tortajada, A.1
Montes, T.2
Martinez-Barricarte, R.3
Morgan, B.P.4
Harris, C.L.5
De Cordoba, S.R.6
-
79
-
-
0029549508
-
Epidemiology of age-related maculopathy
-
Vingerling JR, Klaver CC, Hofman A, de Jong PT (1995) Epidemiology of age-related maculopathy. Epidemiol Rev 17(2):347-360 (Pubitemid 26096879)
-
(1995)
Epidemiologic Reviews
, vol.17
, Issue.2
, pp. 347-360
-
-
Vingerling, J.R.1
Klaver, C.C.W.2
Hofman, A.3
De Jong, P.T.V.M.4
-
80
-
-
0034869253
-
Human C-reactive protein: Expression, structure, and function
-
DOI 10.1016/S0161-5890(01)00042-6, PII S0161589001000426
-
Volanakis JE (2001) Human C-reactive protein: expression, structure, and function. Mol Immunol 38(2-3):189-197 (Pubitemid 32786776)
-
(2001)
Molecular Immunology
, vol.38
, Issue.2-3
, pp. 189-197
-
-
Volanakis, J.E.1
-
81
-
-
67649998898
-
Localization of age-related macular degeneration-associated ARMS2 in cytosol, not mitochondria
-
Wang G, Spencer KL, Court BL, Olson LM, Scott WK, Haines JL, Pericak-Vance MA (2009) Localization of age-related macular degeneration- associated ARMS2 in cytosol, not mitochondria. Invest Ophthalmol Vis Sci 50(7):3084-3090
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, Issue.7
, pp. 3084-3090
-
-
Wang, G.1
Spencer, K.L.2
Court, B.L.3
Olson, L.M.4
Scott, W.K.5
Haines, J.L.6
Pericak-Vance, M.A.7
-
82
-
-
67649230210
-
Structure of complement fragment C3b-factor H and implications for host protection by complement regulators
-
Wu J, Wu YQ, Ricklin D, Janssen BJ, Lambris JD, Gros P (2009) Structure of complement fragment C3b-factor H and implications for host protection by complement regulators. Nat Immunol 10(7):728-733
-
(2009)
Nat Immunol
, vol.10
, Issue.7
, pp. 728-733
-
-
Wu, J.1
Wu, Y.Q.2
Ricklin, D.3
Janssen, B.J.4
Lambris, J.D.5
Gros, P.6
-
84
-
-
33751004690
-
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration
-
DOI 10.1126/science.1133811
-
Yang Z, Camp NJ, Sun H, Tong Z, Gibbs D, Cameron DJ, Chen H, Zhao Y, Pearson E, Li X, Chien J, Dewan A, Harmon J, Bernstein PS, Shridhar V, Zabriskie NA, Hoh J, Howes K, Zhang K (2006) A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science 314(5801):992-993 (Pubitemid 44749944)
-
(2006)
Science
, vol.314
, Issue.5801
, pp. 992-993
-
-
Yang, Z.1
Camp, N.J.2
Sun, H.3
Tong, Z.4
Gibbs, D.5
Cameron, D.J.6
Chen, H.7
Zhao, Y.8
Pearson, E.9
Li, X.10
Chien, J.11
DeWan, A.12
Harmon, J.13
Bernstein, P.S.14
Shridhar, V.15
Zabriskie, N.A.16
Hoh, J.17
Howes, K.18
Zhang, K.19
-
85
-
-
34547764305
-
Complement C3 variant and the risk of age-related macular degeneration
-
DOI 10.1056/NEJMoa072618
-
Yates JR, Sepp T, Matharu BK, Khan JC, Thurlby DA, Shahid H, Clayton DG, Hayward C, Morgan J, Wright AF, Armbrecht AM, Dhillon B, Deary IJ, Redmond E, Bird AC, Moore AT (2007) Complement C3 variant and the risk of age-related macular degeneration. N Engl J Med 357(6):553-561 (Pubitemid 47236280)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.6
, pp. 553-561
-
-
Yates, J.R.W.1
Sepp, T.2
Matharu, B.K.3
Khan, J.C.4
Thurlby, D.A.5
Shahid, H.6
Clayton, D.G.7
Hayward, C.8
Morgan, J.9
Wright, A.F.10
Armbrecht, A.M.11
Dhillon, B.12
Deary, I.J.13
Redmond, E.14
Bird, A.C.15
Moore, A.T.16
-
86
-
-
34447581121
-
Biochemical analysis of a common human polymorphism associated with age-related macular degeneration
-
DOI 10.1021/bi700459a
-
Yu J, Wiita P, Kawaguchi R, Honda J, Jorgensen A, Zhang K, Fischetti VA, Sun H (2007) Biochemical analysis of a common human polymorphism associated with age-related macular degeneration. Biochemistry 46(28):8451-8461 (Pubitemid 47075982)
-
(2007)
Biochemistry
, vol.46
, Issue.28
, pp. 8451-8461
-
-
Yu, J.1
Wiita, P.2
Kawaguchi, R.3
Honda, J.4
Jorgensen, A.5
Zhang, K.6
Fischetti, V.A.7
Sun, H.8
-
87
-
-
0032448463
-
Age-related macular degeneration: Review of pathogenesis
-
Zarbin MA (1998) Age-related macular degeneration: review of pathogenesis. Eur J Ophthalmol 8(4):199-206 (Pubitemid 29049380)
-
(1998)
European Journal of Ophthalmology
, vol.8
, Issue.4
, pp. 199-206
-
-
Zarbin, M.A.1
-
88
-
-
70249115440
-
Complement and immune defense: From innate immunity to human diseases
-
Zipfel PF (2009) Complement and immune defense: from innate immunity to human diseases. Immunol Lett 126(1-2):1-7
-
(2009)
Immunol Lett
, vol.126
, Issue.1-2
, pp. 1-7
-
-
Zipfel, P.F.1
-
89
-
-
34047200899
-
Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome
-
Zipfel PF, Edey M, Heinen S, Jozsi M, Richter H, Misselwitz J, Hoppe B, Routledge D, Strain L, Hughes AE, Goodship JA, Licht C, Goodship TH, Skerka C (2007) Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome. PLoS Genet 3(3):e41
-
(2007)
PLoS Genet
, vol.3
, Issue.3
-
-
Zipfel, P.F.1
Edey, M.2
Heinen, S.3
Jozsi, M.4
Richter, H.5
Misselwitz, J.6
Hoppe, B.7
Routledge, D.8
Strain, L.9
Hughes, A.E.10
Goodship, J.A.11
Licht, C.12
Goodship, T.H.13
Skerka, C.14
-
90
-
-
22544431912
-
Complement and diseases: Defective alternative pathway control results in kidney and eye diseases
-
DOI 10.1016/j.molimm.2005.06.015, PII S0161589005002063, 10th Meeting on Complement in Human Disease
-
Zipfel PF, Heinen S, Jozsi M, Skerka C (2006) Complement and diseases: defective alternative pathway control results in kidney and eye diseases. Mol Immunol 43(1-2):97-106 (Pubitemid 41021526)
-
(2006)
Molecular Immunology
, vol.43
, Issue.1-2
, pp. 97-106
-
-
Zipfel, P.F.1
Heinen, S.2
Jozsi, M.3
Skerka, C.4
-
91
-
-
0033033505
-
FHL-1/reconectin: A human complement and immune regulator with cell- adhesive function
-
DOI 10.1016/S0167-5699(98)01432-7, PII S0167569998014327
-
Zipfel PF, Skerka C (1999) FHL-1/reconectin: a human complement and immune regulator with cell-adhesive function. Immunol Today 20(3):135-140 (Pubitemid 29130343)
-
(1999)
Immunology Today
, vol.20
, Issue.3
, pp. 135-140
-
-
Zipfel, P.F.1
Skerka, C.2
-
92
-
-
70349437186
-
Complement regulators and inhibitory proteins
-
Zipfel PF, Skerka C (2009) Complement regulators and inhibitory proteins. Nat Rev Immunol 9(10):729-740
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.10
, pp. 729-740
-
-
Zipfel, P.F.1
Skerka, C.2
|