메뉴 건너뛰기




Volumn 292, Issue 1, 2007, Pages

Iron absorption and hepatic iron uptake are increased in a transferrin receptor 2 (Y245X) mutant mouse model of hemochromatosis type 3

Author keywords

Hepcidin; Hereditary hemochromatosis; Iron metabolism; Liver iron overload and transferrin receptor 2

Indexed keywords

HEPCIDIN; IRON; TRANSFERRIN RECEPTOR 2;

EID: 33846164453     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00278.2006     Document Type: Article
Times cited : (45)

References (40)
  • 2
    • 0037103357 scopus 로고    scopus 로고
    • Regulation of iron absorption in Hfe mutant mice
    • Ajioka RS, Levy JE, Andrews NC, Kushner JP. Regulation of iron absorption in Hfe mutant mice. Blood 100: 1465-1469, 2002.
    • (2002) Blood , vol.100 , pp. 1465-1469
    • Ajioka, R.S.1    Levy, J.E.2    Andrews, N.C.3    Kushner, J.P.4
  • 3
    • 0344514886 scopus 로고    scopus 로고
    • Identification of new mutations of the HFE, hepcidin, and transferrin receptor 2 genes by denaturing HPLC analysis of individuals with biochemical indications of iron overload
    • Biasiotto G, Belloli S, Ruggeri G, Zanella I, Gerardi G, Corrado M, Gobbi E, Albertini A, Arosio P. Identification of new mutations of the HFE, hepcidin, and transferrin receptor 2 genes by denaturing HPLC analysis of individuals with biochemical indications of iron overload. Clin Chem 49: 1981-1988, 2003.
    • (2003) Clin Chem , vol.49 , pp. 1981-1988
    • Biasiotto, G.1    Belloli, S.2    Ruggeri, G.3    Zanella, I.4    Gerardi, G.5    Corrado, M.6    Gobbi, E.7    Albertini, A.8    Arosio, P.9
  • 4
    • 0022345593 scopus 로고
    • Efficient clearance of non-transferrin-bound iron by rat liver. Implications for hepatic iron loading in iron overload states
    • Brissot P, Wright TL, Ma WL, Weisiger RA. Efficient clearance of non-transferrin-bound iron by rat liver. Implications for hepatic iron loading in iron overload states. J Clin Invest 76: 1463-1470, 1985.
    • (1985) J Clin Invest , vol.76 , pp. 1463-1470
    • Brissot, P.1    Wright, T.L.2    Ma, W.L.3    Weisiger, R.A.4
  • 6
    • 28444466958 scopus 로고    scopus 로고
    • Understanding iron homeostasis through genetic analysis of hemochromatosis and related disorders
    • Camaschella C. Understanding iron homeostasis through genetic analysis of hemochromatosis and related disorders. Blood 106: 3710-3717, 2005.
    • (2005) Blood , vol.106 , pp. 3710-3717
    • Camaschella, C.1
  • 7
    • 28844506080 scopus 로고    scopus 로고
    • Limited iron export by hepatocytes contributes to hepatic iron loading in the Hfe knockout mice
    • Chua ACG, Drake SF, Herbison CE, Olynyk JK, Leedman PJ, Trinder D. Limited iron export by hepatocytes contributes to hepatic iron loading in the Hfe knockout mice. J Hepatol 44: 176-182, 2006.
    • (2006) J Hepatol , vol.44 , pp. 176-182
    • Chua, A.C.G.1    Drake, S.F.2    Herbison, C.E.3    Olynyk, J.K.4    Leedman, P.J.5    Trinder, D.6
  • 8
    • 4444226451 scopus 로고    scopus 로고
    • Nontransferrin bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis
    • Chua ACG, Olynyk JK, Leedman PJ, Trinder D. Nontransferrin bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis. Blood 104: 1519-1525, 2004.
    • (2004) Blood , vol.104 , pp. 1519-1525
    • Chua, A.C.G.1    Olynyk, J.K.2    Leedman, P.J.3    Trinder, D.4
  • 10
    • 0002560546 scopus 로고
    • Serum iron and iron binding capacity
    • edited by Cook JD. New York: Churchill Livingstone
    • Fielding J. Serum iron and iron binding capacity. In: Methods in Hematology Iron, edited by Cook JD. New York: Churchill Livingstone, 1980.
    • (1980) Methods in Hematology Iron
    • Fielding, J.1
  • 17
    • 10244265904 scopus 로고    scopus 로고
    • Diferric transferrin regulates transferrin receptor 2 protein stability
    • Johnson MB, Enns CA. Diferric transferrin regulates transferrin receptor 2 protein stability. Blood 104: 4287-4293, 2004.
    • (2004) Blood , vol.104 , pp. 4287-4293
    • Johnson, M.B.1    Enns, C.A.2
  • 18
    • 0013667111 scopus 로고
    • Studies on intermediary iron metabolism. V. The measurement of non-haemoglobin tissue iron
    • Kaldor I. Studies on intermediary iron metabolism. V. The measurement of non-haemoglobin tissue iron. Aust J Exp Biol Med Sci 32: 795-800, 1954.
    • (1954) Aust J Exp Biol Med Sci , vol.32 , pp. 795-800
    • Kaldor, I.1
  • 20
    • 0034595856 scopus 로고    scopus 로고
    • Transferrin receptor 2-α supports cell growth both in iron-chelated cultured cells and in vivo
    • Kawabata H, Germain RS, Vuong PT, Nakamaki T, Said JW, Koeffler HP. Transferrin receptor 2-α supports cell growth both in iron-chelated cultured cells and in vivo. J Biol Chem 275: 16618-16625, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 16618-16625
    • Kawabata, H.1    Germain, R.S.2    Vuong, P.T.3    Nakamaki, T.4    Said, J.W.5    Koeffler, H.P.6
  • 22
    • 0033597780 scopus 로고    scopus 로고
    • Molecular cloning of transferrin receptor. 2. A new member of the transferrin receptor-like family
    • Kawabata H, Yang R, Hirama T, Vuong PT, Kawano S, Gombart AF, Koeffler HP. Molecular cloning of transferrin receptor. 2. A new member of the transferrin receptor-like family. J Biol Chem 274: 20826-20832, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 20826-20832
    • Kawabata, H.1    Yang, R.2    Hirama, T.3    Vuong, P.T.4    Kawano, S.5    Gombart, A.F.6    Koeffler, H.P.7
  • 25
    • 2942582341 scopus 로고    scopus 로고
    • Early onset hereditary hemochromatosis resulting from a novel TFR2 gene nonsense mutation (R105X) in two siblings of north French descent
    • Le Gac G, Mons F, Jacolot S, Scotet V, Ferec C, Frebourg T. Early onset hereditary hemochromatosis resulting from a novel TFR2 gene nonsense mutation (R105X) in two siblings of north French descent. Br J Haematol 125: 674-8, 2004.
    • (2004) Br J Haematol , vol.125 , pp. 674-678
    • Le Gac, G.1    Mons, F.2    Jacolot, S.3    Scotet, V.4    Ferec, C.5    Frebourg, T.6
  • 26
    • 0141866926 scopus 로고    scopus 로고
    • Effects of cell proliferation on the uptake of transferrin-bound iron by human hepatoma cells
    • Lee AW, Oates PS, Trinder D. Effects of cell proliferation on the uptake of transferrin-bound iron by human hepatoma cells. Hepatology 38: 967-977, 2003.
    • (2003) Hepatology , vol.38 , pp. 967-977
    • Lee, A.W.1    Oates, P.S.2    Trinder, D.3
  • 27
    • 0342264467 scopus 로고    scopus 로고
    • Determination of non-transferrin-bound iron in genetic hemochromatosis using a new HPLC-based method
    • Loreal O, Gosriwatana I, Guyader D, Porter J, Brissot P, Hider RC. Determination of non-transferrin-bound iron in genetic hemochromatosis using a new HPLC-based method. J Hepatol 32: 727-733, 2000.
    • (2000) J Hepatol , vol.32 , pp. 727-733
    • Loreal, O.1    Gosriwatana, I.2    Guyader, D.3    Porter, J.4    Brissot, P.5    Hider, R.C.6
  • 31
  • 32
    • 0033922680 scopus 로고    scopus 로고
    • Gastrointestinal function, divalent metal transporter-1 expression and intestinal iron absorption
    • Oates PS, Trinder D, Morgan EH. Gastrointestinal function, divalent metal transporter-1 expression and intestinal iron absorption. Pflügers Arch 440: 496-502, 2000.
    • (2000) Pflügers Arch , vol.440 , pp. 496-502
    • Oates, P.S.1    Trinder, D.2    Morgan, E.H.3
  • 35
    • 10244255021 scopus 로고    scopus 로고
    • Regulation of transferrin receptor 2 protein levels by transferrin
    • Robb A and Wessling-Resnick M. Regulation of transferrin receptor 2 protein levels by transferrin. Blood 104: 4294-4299, 2004.
    • (2004) Blood , vol.104 , pp. 4294-4299
    • Robb, A.1    Wessling-Resnick, M.2
  • 36
    • 8644221378 scopus 로고    scopus 로고
    • Transferrin receptor 2 mediates a biphasic pattern of transferrin uptake associated with ligand delivery to multivesicular bodies
    • Robb A, Ericsson M, and Wessling-Resnick M. Transferrin receptor 2 mediates a biphasic pattern of transferrin uptake associated with ligand delivery to multivesicular bodies. Am J Physiol Cell Physiol 287: C1769-C1775, 2004.
    • (2004) Am J Physiol Cell Physiol , vol.287
    • Robb, A.1    Ericsson, M.2    Wessling-Resnick, M.3
  • 39
    • 21044434748 scopus 로고    scopus 로고
    • First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin
    • Wallace DF, Summerville L, Lusby PE, Subramaniam VN. First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin. Gut 54: 980-986, 2005.
    • (2005) Gut , vol.54 , pp. 980-986
    • Wallace, D.F.1    Summerville, L.2    Lusby, P.E.3    Subramaniam, V.N.4
  • 40
    • 0034623930 scopus 로고    scopus 로고
    • Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE
    • West AP Jr, Bennett MJ, Sellers VM, Andrews NC, Enns CA, Bjorkman PJ. Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE. J Biol Chem 275: 38135-38138, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 38135-38138
    • West Jr, A.P.1    Bennett, M.J.2    Sellers, V.M.3    Andrews, N.C.4    Enns, C.A.5    Bjorkman, P.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.