Purification, partial characterization and antitumor effect of an exopolysaccharide from Rhizopus nigricans

International Journal of Biological Macromolecules

Volumn 82, Issue , 2016, Pages 299-307

  Yu, Wenqian ^a,b   Chen, Guochuang ^a   Zhang, Pengying ^a   Chen, Kaoshan ^a  

^a SHANDONG UNIVERSITY   (China)

^b JINAN MILITARY GENERAL HOSPITAL   (China)

Author keywords

Apoptosis; Exopolysaccharide; Human colorectal cancer cell; Rhizopus nigricans; S phase cell cycle arrest

Indexed keywords

EXOPOLYSACCHARIDE; EXOPOLYSACCHARIDE 1 1; FRUCTOSE; GALACTOSE; GLUCOSE; MANNOSE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; FUNGAL POLYSACCHARIDE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CARBOHYDRATE ANALYSIS; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL STRUCTURE; CHEMICAL COMPOSITION; COLORECTAL CARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG ISOLATION; DRUG PURIFICATION; FERMENTATION MEDIUM; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HCT116 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR WEIGHT; NONHUMAN; OXIDATIVE STRESS; PHYSICAL CHEMISTRY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHIZOPUS STOLONIFER; S PHASE CELL CYCLE CHECKPOINT; UPREGULATION; CELL CYCLE CHECKPOINT; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; GENETICS; HCT 116 CELL LINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METABOLISM; RHIZOPUS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FUNGAL POLYSACCHARIDES; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MOLECULAR WEIGHT; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; RHIZOPUS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84951829412     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2015.10.005     Document Type: Article

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