Khz-cp (crude polysaccharide extract obtained from the fusion of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis by increasing intracellular calcium levels and activating P38 and NADPH oxidase-dependent generation of reactive oxygen species in SNU-1 cells

BMC Complementary and Alternative Medicine

Volumn 14, Issue , 2014, Pages

  Kim, Tae H ^a   Kim, Ju S ^b   Kim, Zoo H ^c   Huang, Ren B ^a   Chae, Young L ^d   Wang, Ren S ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c NAGOYA UNIVERSITY   (Japan)

^d Korea Inst of Sci and Engineering   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CALCIUM; CYTOCHROME C; FUNGAL POLYSACCHARIDE; KHZ CP; PROTEIN BCL 2; PROTEIN P47; PROTEIN P67; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CANCER INHIBITION; CELL MEMBRANE; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ISOLATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME SUBUNIT; FLOW CYTOMETRY; GANODERMA LUCIDUM; GASTRIC CANCER CELL LINE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; MYCELIUM; OXIDATIVE STRESS; POLYPORUS UMBELLATUS; PROTEIN PHOSPHORYLATION; TRANSFORMED CELL; WESTERN BLOTTING;

APOPTOSIS; CALCIUM; CELL LINE, TUMOR; ENZYME ACTIVATION; FUNGAL POLYSACCHARIDES; HUMANS; NADPH OXIDASE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; POLYPORUS; REACTIVE OXYGEN SPECIES; REISHI; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TISSUE EXTRACTS;

EID: 84903869466     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-236     Document Type: Article

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