Telomerase deficiency causes alveolar stem cell senescence-associated low-grade inflammation in lungs

Journal of Biological Chemistry

Volumn 290, Issue 52, 2015, Pages 30813-30829

  Chen, Ruping ^a,b   Zhang, Kexiong ^b   Chen, Hao ^b   Zhao, Xiaoyin ^b   Wang, Jianqiu ^b   Li, Li ^b   Cong, Yusheng ^b   Ju, Zhenyu ^b   Xu, Dakang ^b,c,d   Williams, Bryan R G ^b,c   Jia, Jihui ^a   Liu, Jun Ping ^a,b,c,d,e  

^a SHANDONG UNIVERSITY   (China)

^b HANGZHOU NORMAL UNIVERSITY   (China)

^c HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d MONASH UNIVERSITY   (Australia)

^e MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CELL CULTURE; CELL PROLIFERATION; GENE EXPRESSION; MUSCLE; PATHOLOGY; PATTERN RECOGNITION; PROTEINS;

BRONCHOALVEOLAR LAVAGE FLUID; CELLULAR INFILTRATION; MONOCYTE CHEMOTACTIC PROTEIN-1; PATTERN RECOGNITION RECEPTORS; PRO-INFLAMMATORY CYTOKINES; REPLICATIVE SENESCENCE; SMOOTH MUSCLE ACTINS; TELOMERASE REVERSE TRANSCRIPTASE;

STEM CELLS;

ALPHA SMOOTH MUSCLE ACTIN; CD11B ANTIGEN; CD16 ANTIGEN; CD45 ANTIGEN; COLLAGEN TYPE 1; FC RECEPTOR IIA; FC RECEPTOR IIB; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; TELOMERASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; RNA; TELOMERASE RNA; TERT PROTEIN, MOUSE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRONCHOALVEOLAR LAVAGE FLUID; CELL DIFFERENTIATION; CELL INFILTRATION; CELL POPULATION; CELL SELECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; ENZYME DEFICIENCY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; HETEROZYGOSITY; HOMOZYGOSITY; IMMUNOREACTIVITY; INNATE IMMUNITY; KNOCKOUT GENE; LUNG ALVEOLUS CELL; MALE; MONONUCLEAR CELL; MOUSE; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PNEUMONIA; PREMATURE AGING; PRIORITY JOURNAL; SENESCENCE; STEM CELL; TELOMERASE DEFICIENCY; TERC GENE; TERT GENE; ANIMAL; C57BL MOUSE; CELL AGING; CYTOLOGY; DEFICIENCY; ENZYMOLOGY; GENETICS; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; LUNG; LUNG ALVEOLUS; LUNG DISEASE; PATHOPHYSIOLOGY;

ANIMALS; CELL AGING; FEMALE; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; LUNG; LUNG DISEASES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PULMONARY ALVEOLI; RNA; STEM CELLS; TELOMERASE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84951797366     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.681619     Document Type: Article

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