Pulmonary fibrosis, bone marrow failure, and telomerase mutation

New England Journal of Medicine

Volumn 366, Issue 16, 2012, Pages 1551-1553

  Gansner, John M ^a   Rosas, Ivan O ^a   Ebert, Benjamin L ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AMINO ACID SUBSTITUTION; BONE MARROW DEPRESSION; CASE REPORT; FAMILY HISTORY; FIBROSING ALVEOLITIS; GENE SEQUENCE; GENETIC ASSOCIATION; HUMAN; LETTER; LUNG FIBROSIS; MALE; MUTATIONAL ANALYSIS; MUTATOR GENE; PRIORITY JOURNAL; TELOMERASE REVERSE TRANSCRIPTASE GENE; TELOMERE;

EID: 84859876918     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc1200999     Document Type: Letter

References (4)

1. Calado RT, Young NS. Telomere maintenance and human bone marrow failure. Blood 2008;111:4446-55.
2. Armanios M. Syndromes of telomere shortening. Annu Rev Genomics Hum Genet 2009;10:45-61.
3. Alder JK, Chen JJ, Lancaster L, et al. Short telomeres are a risk factor for idiopathic pulmonary fibrosis. Proc Natl Acad Sci U S A 2008;105:13051-6.
4. Arai K, Masutomi K, Khurts S, Kaneko S, Kobayashi K, Murakami S. Two independent regions of human telomerase reverse transcriptase are important for its oligomerization and telomerase activity. J Biol Chem 2002;277:8538-44. (Pubitemid 34968317)