메뉴 건너뛰기




Volumn 309, Issue 12, 2015, Pages L1420-L1429

Role of gadd45a in murine models of radiation- and bleomycin-induced lung injury

Author keywords

Akt; Bleomycin; GADD45a; Lung fibrosis; Lung injury; Radiation pneumonitis

Indexed keywords

ALBUMIN; BLEOMYCIN; COLLAGEN; CYTOKINE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45 ALPHA; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; GADD45A PROTEIN, MOUSE; NUCLEAR PROTEIN;

EID: 84951007601     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00146.2014     Document Type: Article
Times cited : (13)

References (40)
  • 3
    • 42549131009 scopus 로고    scopus 로고
    • Microarray analysis of p53-dependent gene expression in response to hypoxia and DNA damage
    • Corn PG, El-Deiry WS. Microarray analysis of p53-dependent gene expression in response to hypoxia and DNA damage. Cancer Biol Ther 6: 1858-1866, 2007
    • (2007) Cancer Biol Ther , vol.6 , pp. 1858-1866
    • Corn, P.G.1    El-Deiry, W.S.2
  • 4
    • 38649104783 scopus 로고    scopus 로고
    • Randomized trial comparing, bleomycin/etoposide/ cisplatin with alternating cisplatin/cyclophosphamide/doxorubicin and vinblastine/bleomycin regimens of chemotherapy for patients with intermediate- and poor-risk metastatic nonseminomatous germ cell tumors: Genito-Urinary Group of the French Federation of Cancer Centers Trial T93MP
    • Culine S, Kramar A, Theodore C, Geoffrois L, Chevreau C, Biron P, Nguyen BB, Heron JF, Kerbrat P, Caty A, Delva R, Fargeot P, Fizazi K, Bouzy J, Droz JP. Randomized trial comparing, bleomycin/etoposide/ cisplatin with alternating cisplatin/cyclophosphamide/doxorubicin and vinblastine/bleomycin regimens of chemotherapy for patients with intermediate- and poor-risk metastatic nonseminomatous germ cell tumors: Genito-Urinary Group of the French Federation of Cancer Centers Trial T93MP. J Clin Oncol 26: 421-427, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 421-427
    • Culine, S.1    Kramar, A.2    Theodore, C.3    Geoffrois, L.4    Chevreau, C.5    Biron, P.6    Nguyen, B.B.7    Heron, J.F.8    Kerbrat, P.9    Caty, A.10    Delva, R.11    Fargeot, P.12    Fizazi, K.13    Bouzy, J.14    Droz, J.P.15
  • 5
    • 0035868896 scopus 로고    scopus 로고
    • Equivalence of three or four cycles of bleomycin, etoposide, and cisplatin chemotherapy and of a 3- or 5-day schedule in good-prognosis germ cell cancer: A randomized study of the European Organization for Research and Treatment of Cancer Genitourinary Tract Cancer Cooperative Group and the Medical Research Council
    • de Wit R, Roberts JT, Wilkinson PM, de Mulder PH, Mead GM, Fossa SD, Cook P, de Prijck L, Stenning S, Collette L. Equivalence of three or four cycles of bleomycin, etoposide, and cisplatin chemotherapy and of a 3- or 5-day schedule in good-prognosis germ cell cancer: a randomized study of the European Organization for Research and Treatment of Cancer Genitourinary Tract Cancer Cooperative Group and the Medical Research Council. J Clin Oncol 19: 1629-1640, 2001
    • (2001) J Clin Oncol , vol.19 , pp. 1629-1640
    • De Wit, R.1    Roberts, J.T.2    Wilkinson, P.M.3    De Mulder, P.H.4    Mead, G.M.5    Fossa, S.D.6    Cook, P.7    De Prijck, L.8    Stenning, S.9    Collette, L.10
  • 6
    • 0031005803 scopus 로고    scopus 로고
    • Importance of bleomycin in combination chemotherapy for good-prognosis testicular nonseminoma: A randomized study of the European Organization for Research and Treatment of Cancer Genitourinary Tract Cancer Cooperative Group
    • de Wit R, Stoter G, Kaye SB, Sleijfer DT, Jones WG, ten Bokkel Huinink WW, Rea LA, Collette L, Sylvester R. Importance of bleomycin in combination chemotherapy for good-prognosis testicular nonseminoma: a randomized study of the European Organization for Research and Treatment of Cancer Genitourinary Tract Cancer Cooperative Group. J Clin Oncol 15: 1837-1843, 1997
    • (1997) J Clin Oncol , vol.15 , pp. 1837-1843
    • De Wit, R.1    Stoter, G.2    Kaye, S.B.3    Sleijfer, D.T.4    Jones, W.G.5    Ten Bokkel Huinink, W.W.6    Rea, L.A.7    Collette, L.8    Sylvester, R.9
  • 7
    • 80051923056 scopus 로고    scopus 로고
    • TGFbeta- and bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (MTOR)
    • Goc A, Choudhary M, Byzova TV, Somanath PR. TGFbeta- and bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (mTOR). J Cell Physiol 226: 3004-3013, 2013
    • (2013) J Cell Physiol , vol.226 , pp. 3004-3013
    • Goc, A.1    Choudhary, M.2    Byzova, T.V.3    Somanath, P.R.4
  • 10
    • 1842429927 scopus 로고    scopus 로고
    • Gadd45a regulates matrix metalloproteinases by suppressing DeltaNp63alpha and beta-catenin via p38 MAP kinase and APC complex activation
    • Hildesheim J, Belova GI, Tyner SD, Zhou X, Vardanian L, Fornace AJ Jr. Gadd45a regulates matrix metalloproteinases by suppressing DeltaNp63alpha and beta-catenin via p38 MAP kinase and APC complex activation. Oncogene 23: 1829-1837, 2004
    • (2004) Oncogene , vol.23 , pp. 1829-1837
    • Hildesheim, J.1    Belova, G.I.2    Tyner, S.D.3    Zhou, X.4    Vardanian, L.5    Fornace, A.J.6
  • 12
    • 0037048302 scopus 로고    scopus 로고
    • Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a
    • Hollander MC, Fornace AJ Jr. Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a. Oncogene 21: 6228-6233, 2002
    • (2002) Oncogene , vol.21 , pp. 6228-6233
    • Hollander, M.C.1    Fornace, A.J.2
  • 17
    • 0037784056 scopus 로고    scopus 로고
    • Hyperoxia induces Egr-1 expression through activation of extracellular signal-regulated kinase 1/2 pathway
    • Jones N, Agani FH. Hyperoxia induces Egr-1 expression through activation of extracellular signal-regulated kinase 1/2 pathway. J Cell Physiol 196: 326-333, 2003
    • (2003) J Cell Physiol , vol.196 , pp. 326-333
    • Jones, N.1    Agani, F.H.2
  • 18
    • 0025215373 scopus 로고
    • Bleomycin-induced pulmonary toxicity
    • Jules-Elysee K, White DA. Bleomycin-induced pulmonary toxicity. Clin Chest Med 11: 1-20, 1990
    • (1990) Clin Chest Med , vol.11 , pp. 1-20
    • Jules-Elysee, K.1    White, D.A.2
  • 20
    • 0028860147 scopus 로고
    • Importance of bleomycin in favorable-prognosis disseminated germ cell tumors: An Eastern Cooperative Oncology Group trial
    • Loehrer PJ Sr, Johnson D, Elson P, Einhorn LH, Trump D. Importance of bleomycin in favorable-prognosis disseminated germ cell tumors: an Eastern Cooperative Oncology Group trial. J Clin Oncol 13: 470-476, 1995
    • (1995) J Clin Oncol , vol.13 , pp. 470-476
    • Loehrer, P.J.1    Johnson, D.2    Elson, P.3    Einhorn, L.H.4    Trump, D.5
  • 21
    • 0035910750 scopus 로고    scopus 로고
    • Activated Akt protects the lung from oxidant-induced injury and delays death of mice
    • Lu Y, Parkyn L, Otterbein LE, Kureishi Y, Walsh K, Ray A, Ray P. Activated Akt protects the lung from oxidant-induced injury and delays death of mice. J Exp Med 193: 545-549, 2001
    • (2001) J Exp Med , vol.193 , pp. 545-549
    • Lu, Y.1    Parkyn, L.2    Otterbein, L.E.3    Kureishi, Y.4    Walsh, K.5    Ray, A.6    Ray, P.7
  • 27
    • 39149103740 scopus 로고    scopus 로고
    • The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?
    • Moeller A, Ask K, Warburton D, Gauldie J, Kolb M. The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis? Int J Biochem Cell Biol 40: 362-382, 2008
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 362-382
    • Moeller, A.1    Ask, K.2    Warburton, D.3    Gauldie, J.4    Kolb, M.5
  • 28
    • 34147145253 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/ protein kinase Akt negatively regulates plasminogen activator inhibitor type 1 expression in vascular endothelial cells
    • Mukai Y, Wang CY, Rikitake Y, Liao JK. Phosphatidylinositol 3-kinase/ protein kinase Akt negatively regulates plasminogen activator inhibitor type 1 expression in vascular endothelial cells. Am J Physiol Heart Circ Physiol 292: H1937-H1942, 2007
    • (2007) Am J Physiol Heart Circ Physiol , vol.292 , pp. H1937-H1942
    • Mukai, Y.1    Wang, C.Y.2    Rikitake, Y.3    Liao, J.K.4
  • 29
    • 0032867571 scopus 로고    scopus 로고
    • The role of p53 in bleomycin-induced DNA damage in the lung. A comparative study with the small intestine
    • Okudela K, Ito T, Mitsui H, Hayashi H, Udaka N, Kanisawa M, Kitamura H. The role of p53 in bleomycin-induced DNA damage in the lung. A comparative study with the small intestine. Am J Pathol 155: 1341-1351, 1999
    • (1999) Am J Pathol , vol.155 , pp. 1341-1351
    • Okudela, K.1    Ito, T.2    Mitsui, H.3    Hayashi, H.4    Udaka, N.5    Kanisawa, M.6    Kitamura, H.7
  • 33
    • 16844366591 scopus 로고    scopus 로고
    • The autoimmune suppressor Gadd45alpha inhibits the T cell alternative p38 activation pathway
    • Salvador JM, Mittelstadt PR, Belova GI, Fornace AJ Jr, Ashwell JD. The autoimmune suppressor Gadd45alpha inhibits the T cell alternative p38 activation pathway. Nat Immunol 6: 396-402, 2005
    • (2005) Nat Immunol , vol.6 , pp. 396-402
    • Salvador, J.M.1    Mittelstadt, P.R.2    Belova, G.I.3    Fornace, A.J.4    Ashwell, J.D.5
  • 34
    • 59649103079 scopus 로고    scopus 로고
    • Growth arrest and DNA damage-45 alpha (GADD45alpha)
    • Siafakas AR, Richardson DR. Growth arrest and DNA damage-45 alpha (GADD45alpha). Int J Biochem Cell Biol 41: 986-989, 2009
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 986-989
    • Siafakas, A.R.1    Richardson, D.R.2
  • 35
    • 0034827655 scopus 로고    scopus 로고
    • Bleomycin-induced pneumonitis
    • Sleijfer S. Bleomycin-induced pneumonitis. Chest 120: 617-624, 2001
    • (2001) Chest , vol.120 , pp. 617-624
    • Sleijfer, S.1
  • 36
    • 0033784887 scopus 로고    scopus 로고
    • The physical parameters and molecular events associated with radiation-induced lung toxicity
    • Vujaskovic Z, Marks LB, Anscher MS. The physical parameters and molecular events associated with radiation-induced lung toxicity. Semin Radiat Oncol 10: 296-307, 2000
    • (2000) Semin Radiat Oncol , vol.10 , pp. 296-307
    • Vujaskovic, Z.1    Marks, L.B.2    Anscher, M.S.3
  • 37
    • 79957916527 scopus 로고    scopus 로고
    • Effectiveness of tyrosine kinase inhibitors on “uncommon” epidermal growth factor receptor mutations of unknown clinical significance in non-small cell lung cancer
    • Wu JY, Yu CJ, Chang YC, Yang CH, Shih JY, Yang PC. Effectiveness of tyrosine kinase inhibitors on “uncommon” epidermal growth factor receptor mutations of unknown clinical significance in non-small cell lung cancer. Clin Cancer Res 17: 3812-3821, 2011
    • (2011) Clin Cancer Res , vol.17 , pp. 3812-3821
    • Wu, J.Y.1    Yu, C.J.2    Chang, Y.C.3    Yang, C.H.4    Shih, J.Y.5    Yang, P.C.6
  • 38
    • 84864630951 scopus 로고    scopus 로고
    • Deficiency in TR4 nuclear receptor abrogates Gadd45a expression and increases cytotoxicity induced by ionizing radiation
    • Yan SJ, Lee YF, Ting HJ, Liu NC, Liu S, Lin SJ, Yeh SD, Li G, Chang C. Deficiency in TR4 nuclear receptor abrogates Gadd45a expression and increases cytotoxicity induced by ionizing radiation. Cell Mol Biol Lett 17: 309-322, 2012
    • (2012) Cell Mol Biol Lett , vol.17 , pp. 309-322
    • Yan, S.J.1    Lee, Y.F.2    Ting, H.J.3    Liu, N.C.4    Liu, S.5    Lin, S.J.6    Yeh, S.D.7    Li, G.8    Chang, C.9
  • 40
    • 84890451672 scopus 로고    scopus 로고
    • Atorvastatin attenuates bleomycininduced pulmonary fibrosis via suppressing iNOS expression and the CTGF (CCN2)/ERK signaling pathway
    • Zhu B, Ma AQ, Yang L, Dang XM. Atorvastatin attenuates bleomycininduced pulmonary fibrosis via suppressing iNOS expression and the CTGF (CCN2)/ERK signaling pathway. Int J Mol Sci 14: 24476-24491, 2013.
    • (2013) Int J Mol Sci , vol.14 , pp. 24476-24491
    • Zhu, B.1    Ma, A.Q.2    Yang, L.3    Dang, X.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.