Importance of bleomycin in combination chemotherapy for good-prognosis testicular nonseminoma: A randomized study of the European Organization for Research and Treatment of Cancer Genitourinary Tract Cancer Cooperative Group

Journal of Clinical Oncology

Volumn 15, Issue 5, 1997, Pages 1837-1843

  de Wit, R ^a   Stoter, G ^a   Kaye, S B ^a   Sleijfer, D T ^a   Jones, W G ^a   ten Bokkel Huinink, W W ^a   Rea, L A ^a   Collette, L ^a   Sylvester, R ^a  

^a ERASMUS MC CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; CISPLATIN; ETOPOSIDE;

ADOLESCENT; ADULT; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISSEMINATED CANCER; DRUG EFFICACY; HUMAN; LUNG TOXICITY; MAJOR CLINICAL STUDY; MALE; NEUROTOXICITY; NON SEMINOMATOUS GERMINOMA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RAYNAUD PHENOMENON; SECOND CANCER; TESTIS TUMOR;

EID: 0031005803     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1997.15.5.1837     Document Type: Article

References (20)

1. Einhorn LH: Testicular cancer as a model for a curable neoplasm: The Richard and Hinda Rosenthal Foundation award lecture. Cancer Res 41:3275-3280, 1981
2. Stoter G, Koopman A, Vendrik CPJ, et al: Ten-year survival and late sequelae in testicular cancer patients treated with cisplatin, vinblastine and bleomycin. J Clin Oncol 7:1099-1104, 1989
3. Medical Research Council Working Party Report on Testicular Tumours: Prognostic factors in advanced non seminomatous germ cell testicular tumours: Results of a multicentre study. Lancet 1:8-11, 1985
4. Bosl GJ, Geller NL, Cirrincione C, et al: Multivariate analysis of prognostic variables in patients with metastatic testicular cancer. Cancer Res 43:3403-3407, 1983
5. Birch R, Williams S, Cone A, et al: Prognostic factors for favorable outcome in disseminated germ cell tumors. J Clin Oncol 4:400-407, 1986
6. Stoter G, Sylvester R, Sleijfer DT, et al: Multivariate analysis of prognostic variables in patients with disseminated non-seminomatous testicular cancer: Results from an EORTC multi-institutional study. Cancer Res 47:2714-2718, 1987
7. Bajorin D, Katz A, Chan E, et al: Comparison of criteria for assigning germ cell tumor patients to "good risk" and "poor risk" studies. J Clin Oncol 6:786-792, 1988
8. Mead GM, Stenning SP, Parkinson MC: The second Medical Research Council study of prognostic factors in nonseminomatous germ cell tumors. J Clin Oncol 10:85-94, 1992
9. Stoter G, Sleijfer DT, Bokkel Huinink ten WW: High-dose versus low-dose vinblastine in cisplatin-vinblastine-bleomycin combination chemotherapy of non-seminomatous testicular cancer: A randomized study of the EORTC Genitourinary Tract Cancer Cooperative Group. J Clin Oncol 4:1199-1206, 1986
10. Breslow N: Comparison of survival rates, in Buyse ME, Staquet MJ, Sylvester RJ (eds): Cancer Clinical Trials, Methods and Practice. Oxford, United Kingdom, Oxford University Press, 1984, pp 381-406
11. Pugh RCP: Testicular tumours - Introduction, in Pugh RCP (ed): Pathology of the Testis. Oxford, United Kingdom, Blackwell, 1976, pp 139-163
12. Birch R, Williams S, Cone A, et al: Prognostic factors for favorable outcome in disseminated germ cell tumors. J Clin Oncol 4:400-407, 1986
13. Newlands ES, Rustin GJS, Begent RHJ, et al: Further advances in the management of malignant teratomas of the testis and other sites. Lancet 1:948-951, 1983
14. Loehrer PJ, Einhorn LJ, Williams SD: VP-16 plus ifosfamide plus cisplatin as salvage therapy in refractory germ cell cancer. J Clin Oncol 4:528-536, 1986
15. Levi JA, Raghaven D, Harvey V, et al: The importance of bleomycin in combination chemotherapy for good-prognosis germ cell carcinoma. J Clin Oncol 11:1300-1305, 1993
16. Loehrer PJ, Johnson D, Elson P, et al: Importance of bleomycin in favorable-prognosis disseminated germ cell tumors: An Eastern Cooperative Oncology Group trial. J Clin Oncol 13:470-476, 1995
17. Levi JA, Thomson D, Sandeman T, et al: A prospective study of cisplatin-based combination chemotherapy in advanced germ cell malignancy: Role of maintenance and long-term follow-up. J Clin Oncol 6:1154-1160, 1988
18. International Germ Cell Classification: A prognostic factor-based staging system for metastatic germ cell cancers. J Clin Oncol 15:594-603, 1997
19. Comis RL: Bleomycin pulmonary toxicity: Current status and future directions. Semin Oncol 19:64-70, 1992
20. Osanto S, Bukman A, Van Hoek F, et al: Long-term effects of chemotherapy in patients with testicular cancer. J Clin Oncol 10:574-579, 1992