Epithelial pten controls acute lung injury and fibrosis by regulating alveolar epithelial cell integrity

American Journal of Respiratory and Critical Care Medicine

Volumn 187, Issue 3, 2013, Pages 262-275

  Miyoshi, Kahori ^a,b   Yanagi, Shigehisa ^a,b,c   Kawahara, Kohichi ^c   Nishio, Miki ^c   Tsubouchi, Hironobu ^a   Imazu, Yoshifumi ^a   Koshida, Ryusuke ^a   Matsumoto, Nobuhiro ^a   Taguchi, Akiko ^a   Yamashita, Shu Ichi ^c   Suzuki, Akira ^b,c   Nakazato, Masamitsu ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b AKITA UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

Acute lung injury; Lung epithelium; Organ fibrosis; Pten; Tight junctions

Indexed keywords

BLEOMYCIN; CLAUDIN 4; LAMININ; LAMININ BETA1; MATRIX METALLOPROTEINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; S6 KINASE; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UVOMORULIN;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; ENZYME INACTIVATION; EPITHELIUM CELL; GENE; GENE INDUCTION; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PTEN GENE; SURVIVAL RATE; TIGHT JUNCTION;

ACUTE LUNG INJURY; ANIMALS; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; HUMANS; MICE; MICE, KNOCKOUT; PTEN PHOSPHOHYDROLASE; PULMONARY ALVEOLI; PULMONARY FIBROSIS; TIGHT JUNCTIONS;

EID: 84873338159     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201205-0851OC     Document Type: Article

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