Deficiency in TR4 nuclear receptor abrogates Gadd45a expression and increases cytotoxicity induced by ionizing radiation

Cellular and Molecular Biology Letters

Volumn 17, Issue 2, 2012, Pages 309-322

  Yan, Shian Jang ^a   Lee, Yi Fen ^a   Ting, Huei Ju ^a   Liu, Ning Chun ^a   Liu, Su ^a   Lin, Shin Jen ^a   Yeh, Shauh Der ^b   Li, Gonghui ^a   Chang, Chawnshang ^a,c  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

GADD45A; Genotoxic stress; Ionizing radiation; Mouse embryonic fibroblast; TR4; TR4 response element

Indexed keywords

NUCLEAR RECEPTOR NR2C2; CELL CYCLE PROTEIN; GADD45A PROTEIN, MOUSE; NUCLEAR PROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL GROWTH; CELL PROTECTION; CELL STRESS; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOTOXICITY; DNA REPAIR; EMBRYO; EXON; GENE; GENE EXPRESSION REGULATION; GENOTOXICITY; GROWTH ARREST AND DNA DAMAGE INDUCIBLE 45 ALPHA GENE; INTRON; IONIZING RADIATION; MALE; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIATION EXPOSURE; TRANSCRIPTION REGULATION; ANIMAL; APOPTOSIS; CELL CULTURE; CELL CYCLE CHECKPOINT; DRUG ANTAGONISM; FIBROBLAST; GENETICS; METABOLISM; MOUSE MUTANT; RNA INTERFERENCE; UPREGULATION;

MUS;

ANIMALS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; DNA REPAIR; EXONS; FIBROBLASTS; INTRONS; MICE; MICE, KNOCKOUT; NUCLEAR PROTEINS; NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 2; PROMOTER REGIONS, GENETIC; RADIATION, IONIZING; RNA INTERFERENCE; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 84864630951     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-012-0012-9     Document Type: Article

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