-
1
-
-
39349096526
-
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
-
DOI 10.1016/j.cell.2008.01.025, PII S0092867408001256
-
Orkin SH, Zon LI. Hematopoiesis: an evolving paradigm for stem cell biology. Cell. 2008;132(4):631-644. (Pubitemid 351260057)
-
(2008)
Cell
, vol.132
, Issue.4
, pp. 631-644
-
-
Orkin, S.H.1
Zon, L.I.2
-
2
-
-
79952003900
-
DNA damage response in adult stem cells: Pathways and consequences
-
Mandal PK, Blanpain C, Rossi DJ. DNA damage response in adult stem cells: pathways and consequences. Nat Rev Mol Cell Biol. 2011;12(3):198-202.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, Issue.3
, pp. 198-202
-
-
Mandal, P.K.1
Blanpain, C.2
Rossi, D.J.3
-
3
-
-
34250007142
-
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
-
DOI 10.1038/nature05862, PII NATURE05862
-
Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature. 2007;447(7145):725-729. (Pubitemid 46889729)
-
(2007)
Nature
, vol.447
, Issue.7145
, pp. 725-729
-
-
Rossi, D.J.1
Bryder, D.2
Seita, J.3
Nussenzweig, A.4
Hoeijmakers, J.5
Weissman, I.L.6
-
4
-
-
38349132624
-
Deconstructing stem cell self-renewal: Genetic insights into cell-cycle regulation
-
Orford KW, Scadden DT. Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation. Nat Rev Genet. 2008;9(2):115-128.
-
(2008)
Nat Rev Genet
, vol.9
, Issue.2
, pp. 115-128
-
-
Orford, K.W.1
Scadden, D.T.2
-
5
-
-
56549128268
-
Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
-
Wilson A, Laurenti E, Oser G, et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell. 2008;135(6):1118-1129.
-
(2008)
Cell
, vol.135
, Issue.6
, pp. 1118-1129
-
-
Wilson, A.1
Laurenti, E.2
Oser, G.3
-
6
-
-
7244250309
-
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
-
DOI 10.1038/nature02989
-
Ito K, Hirao A, Arai F, et al. Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature. 2004;431(7011):997-1002. (Pubitemid 39434422)
-
(2004)
Nature
, vol.431
, Issue.7011
, pp. 997-1002
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Matsuoka, S.4
Takubo, K.5
Hamaguchi, I.6
Nomiyama, K.7
Hosokawa, K.8
Sakurada, K.9
Nakagata, N.10
Ikeda, Y.11
Mak, T.W.12
Suda, T.13
-
7
-
-
33846419112
-
FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress
-
DOI 10.1016/j.cell.2007.01.003, PII S0092867407000505
-
Tothova Z, Kollipara R, Huntly BJ, et al. FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell. 2007;128(2):325-339. (Pubitemid 46137992)
-
(2007)
Cell
, vol.128
, Issue.2
, pp. 325-339
-
-
Tothova, Z.1
Kollipara, R.2
Huntly, B.J.3
Lee, B.H.4
Castrillon, D.H.5
Cullen, D.E.6
McDowell, E.P.7
Lazo-Kallanian, S.8
Williams, I.R.9
Sears, C.10
Armstrong, S.A.11
Passegue, E.12
DePinho, R.A.13
Gilliland, D.G.14
-
8
-
-
33646351002
-
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
-
DOI 10.1038/nature04747, PII NATURE04747
-
Zhang J, Grindley JC, Yin T, et al. PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature. 2006;441(7092):518-522. (Pubitemid 44050154)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 518-522
-
-
Zhang, J.1
Grindley, J.C.2
Yin, T.3
Jayasinghe, S.4
He, X.C.5
Ross, J.T.6
Haug, J.S.7
Rupp, D.8
Porter-Westpfahl, K.S.9
Wiedemann, L.M.10
Wu, H.11
Li, L.12
-
9
-
-
84860528235
-
The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells
-
Maryanovich M, Oberkovitz G, Niv H, et al. The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells. Nat Cell Biol. 2012;14(5):535-541.
-
(2012)
Nat Cell Biol
, vol.14
, Issue.5
, pp. 535-541
-
-
Maryanovich, M.1
Oberkovitz, G.2
Niv, H.3
-
10
-
-
34250363611
-
Rb Regulates Interactions between Hematopoietic Stem Cells and Their Bone Marrow Microenvironment
-
DOI 10.1016/j.cell.2007.03.055, PII S0092867407005363
-
Walkley CR, Shea JM, Sims NA, Purton LE, Orkin SH. Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment. Cell. 2007;129(6):1081-1095. (Pubitemid 46908695)
-
(2007)
Cell
, vol.129
, Issue.6
, pp. 1081-1095
-
-
Walkley, C.R.1
Shea, J.M.2
Sims, N.A.3
Purton, L.E.4
Orkin, S.H.5
-
11
-
-
58049216794
-
p53 regulates hematopoietic stem cell quiescence
-
Liu Y, Elf SE, Miyata Y, et al. p53 regulates hematopoietic stem cell quiescence. Cell Stem Cell. 2009;4(1):37-48.
-
(2009)
Cell Stem Cell
, vol.4
, Issue.1
, pp. 37-48
-
-
Liu, Y.1
Elf, S.E.2
Miyata, Y.3
-
12
-
-
33749172559
-
INK4a
-
DOI 10.1038/nature05159, PII NATURE05159
-
Janzen V, Forkert R, Fleming HE, et al. Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a. Nature. 2006;443(7110):421-426. (Pubitemid 44477274)
-
(2006)
Nature
, vol.443
, Issue.7110
, pp. 421-426
-
-
Janzen, V.1
Forkert, R.2
Fleming, H.E.3
Saito, Y.4
Waring, M.T.5
Dombkowski, D.M.6
Cheng, T.7
DePinho, R.A.8
Sharpless, N.E.9
Scadden, D.T.10
-
13
-
-
31544463261
-
Cip1/Waf1 in opposite manners
-
DOI 10.1182/blood-2005-02-0685
-
Yu H, Yuan Y, Shen H, Cheng T. Hematopoietic stem cell exhaustion impacted by p18 INK4C and p21 Cip1/Waf1 in opposite manners. Blood. 2006;107(3):1200-1206. (Pubitemid 43156324)
-
(2006)
Blood
, vol.107
, Issue.3
, pp. 1200-1206
-
-
Yu, H.1
Yuan, Y.2
Shen, H.3
Cheng, T.4
-
14
-
-
0034629129
-
Hematopoietic stem cell quiescence maintained by p21cip1/waf1
-
Cheng T, Rodrigues N, Shen H, et al. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science. 2000;287(5459):1804-1808.
-
(2000)
Science
, vol.287
, Issue.5459
, pp. 1804-1808
-
-
Cheng, T.1
Rodrigues, N.2
Shen, H.3
-
15
-
-
80052281899
-
p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70
-
Zou P, Yoshihara H, Hosokawa K, et al. p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70. Cell Stem Cell. 2011;9(3):247-261.
-
(2011)
Cell Stem Cell
, vol.9
, Issue.3
, pp. 247-261
-
-
Zou, P.1
Yoshihara, H.2
Hosokawa, K.3
-
16
-
-
10444235646
-
Gadd45a, a p53- and BRCA1-regulated stress protein, in cellular response to DNA damage
-
DOI 10.1016/j.mrfmmm.2004.06.055, PII S0027510704003781, Stress Responses
-
Zhan Q. Gadd45a, a p53- and BRCA1-regulated stress protein, in cellular response to DNA damage. Mutat Res. 2005;569(1-2):133-143. (Pubitemid 39643263)
-
(2005)
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
, vol.569
, Issue.1-2
, pp. 133-143
-
-
Zhan, Q.1
-
17
-
-
83855164048
-
Gadd45 proteins: Relevance to aging, longevity and age-related pathologies
-
Moskalev AA, Smit-McBride Z, Shaposhnikov MV, et al. Gadd45 proteins: relevance to aging, longevity and age-related pathologies. Ageing Res Rev. 2012;11(1):51-66.
-
(2012)
Ageing Res Rev
, vol.11
, Issue.1
, pp. 51-66
-
-
Moskalev, A.A.1
Smit-McBride, Z.2
Shaposhnikov, M.V.3
-
18
-
-
60549108922
-
Methylation-mediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target
-
Ramachandran K, Gopisetty G, Gordian E, et al. Methylation-mediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target. Cancer Res. 2009;69(4):1527-1535.
-
(2009)
Cancer Res
, vol.69
, Issue.4
, pp. 1527-1535
-
-
Ramachandran, K.1
Gopisetty, G.2
Gordian, E.3
-
19
-
-
17844395749
-
Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer
-
DOI 10.1038/sj.onc.1208464
-
Wang W, Huper G, Guo Y, Murphy SK, Olson JA Jr, Marks JR. Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer. Oncogene. 2005;24(16):2705-2714. (Pubitemid 40593098)
-
(2005)
Oncogene
, vol.24
, Issue.16
, pp. 2705-2714
-
-
Wang, W.1
Huper, G.2
Guo, Y.3
Murphy, S.K.4
Olson Jr., J.A.5
Marks, J.R.6
-
20
-
-
84880312982
-
GADD45A methylation predicts poor overall survival in acute myeloid leukemia and is associated with IDH1/2 and DNMT3A mutations
-
Perugini M, Iarossi DG, Kok CH, et al. GADD45A methylation predicts poor overall survival in acute myeloid leukemia and is associated with IDH1/2 and DNMT3A mutations. Leukemia. 2013;27(7):1588-1592.
-
(2013)
Leukemia
, vol.27
, Issue.7
, pp. 1588-1592
-
-
Perugini, M.1
Iarossi, D.G.2
Kok, C.H.3
-
21
-
-
27944502181
-
Hematopoietic cells from Gadd45a- and Gadd45b-deficient mice are sensitized to genotoxic-stress-induced apoptosis
-
DOI 10.1038/sj.onc.1208847, PII 1208847
-
Gupta M, Gupta SK, Balliet AG, et al. Hematopoietic cells from Gadd45a- and Gadd45b-deficient mice are sensitized to genotoxic-stress-induced apoptosis. Oncogene. 2005;24(48):7170-7179. (Pubitemid 41679279)
-
(2005)
Oncogene
, vol.24
, Issue.48
, pp. 7170-7179
-
-
Gupta, M.1
Gupta, S.K.2
Balliet, A.G.3
Hollander, M.C.4
Fornace Jr., A.J.5
Hoffman, B.6
Liebermann, D.A.7
-
22
-
-
34250654965
-
The comet assay: A method to measure DNA damage in individual cells
-
Olive PL, Banáth JP. The comet assay: a method to measure DNA damage in individual cells. Nat Protoc. 2006;1(1):23-29.
-
(2006)
Nat Protoc
, vol.1
, Issue.1
, pp. 23-29
-
-
Olive, P.L.1
Banáth, J.P.2
-
23
-
-
33646479480
-
Lentiviral vectors pseudotyped with murine ecotropic envelope: Increased biosafety and convenience in preclinical research
-
Schambach A, Galla M, Modlich U, et al. Lentiviral vectors pseudotyped with murine ecotropic envelope: increased biosafety and convenience in preclinical research. Exp Hematol. 2006;34(5):588-592.
-
(2006)
Exp Hematol
, vol.34
, Issue.5
, pp. 588-592
-
-
Schambach, A.1
Galla, M.2
Modlich, U.3
-
24
-
-
21044444012
-
Gadd45a expression induces bim dissociation from the cytoskeleton and translocation to mitochondria
-
DOI 10.1128/MCB.25.11.4488-4500.2005
-
Tong T, Ji J, Jin S, et al. Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria. Mol Cell Biol. 2005;25(11):4488-4500. (Pubitemid 40705755)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.11
, pp. 4488-4500
-
-
Tong, T.1
Ji, J.2
Jin, S.3
Li, X.4
Fan, W.5
Song, Y.6
Wang, M.7
Liu, Z.8
Wu, M.9
Zhan, Q.10
-
25
-
-
77956233247
-
A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal
-
Milyavsky M, Gan OI, Trottier M, et al. A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal. Cell Stem Cell. 2010;7(2):186-197.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.2
, pp. 186-197
-
-
Milyavsky, M.1
Gan, O.I.2
Trottier, M.3
-
26
-
-
77956251480
-
Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis
-
Mohrin M, Bourke E, Alexander D, et al. Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis. Cell Stem Cell. 2010;7(2):174-185.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.2
, pp. 174-185
-
-
Mohrin, M.1
Bourke, E.2
Alexander, D.3
-
27
-
-
84874611142
-
DNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisions
-
Insinga A, Cicalese A, Faretta M, et al. DNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisions. Proc Natl Acad Sci U S A. 2013;110(10):3931-3936.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.10
, pp. 3931-3936
-
-
Insinga, A.1
Cicalese, A.2
Faretta, M.3
-
28
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
DOI 10.1038/35102167
-
Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature. 2001;414(6859):105-111. (Pubitemid 33041634)
-
(2001)
Nature
, vol.414
, Issue.6859
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
|