-
1
-
-
0034524938
-
Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus
-
Shah P, et al. (2000) Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus. J Clin Endocrinol Metab 85(11):4053-4059.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, Issue.11
, pp. 4053-4059
-
-
Shah, P.1
-
2
-
-
85019302509
-
Comparison of the fatty acid composition of the serum phospholipids of controls, prediabetics and adults with type 2 diabetes
-
Chuang LT, et al. (2012) Comparison of the fatty acid composition of the serum phospholipids of controls, prediabetics and adults with type 2 diabetes. J Diabetes Mellitus 2(4):393-401.
-
(2012)
J Diabetes Mellitus
, vol.2
, Issue.4
, pp. 393-401
-
-
Chuang, L.T.1
-
3
-
-
84920605320
-
A new biology of diabetes revealed by leptin
-
Unger RH, Roth MG (2015) A new biology of diabetes revealed by leptin. Cell Metab 21(1):15-20.
-
(2015)
Cell Metab
, vol.21
, Issue.1
, pp. 15-20
-
-
Unger, R.H.1
Roth, M.G.2
-
4
-
-
79961187183
-
The role of dysregulated glucagon secretion in type 2 diabetes
-
D'Alessio D (2011) The role of dysregulated glucagon secretion in type 2 diabetes. Diabetes Obes Metab 13(Suppl 1):126-132.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 126-132
-
-
D'Alessio, D.1
-
5
-
-
0038707331
-
Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea
-
Yoon KH, et al. (2003) Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea. J Clin Endocrinol Metab 88(5):2300-2308.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.5
, pp. 2300-2308
-
-
Yoon, K.H.1
-
6
-
-
0020623615
-
Cellular composition of the human diabetic pancreas
-
Rahier J, Goebbels RM, Henquin JC (1983) Cellular composition of the human diabetic pancreas. Diabetologia 24(5):366-371.
-
(1983)
Diabetologia
, vol.24
, Issue.5
, pp. 366-371
-
-
Rahier, J.1
Goebbels, R.M.2
Henquin, J.C.3
-
7
-
-
10744222060
-
Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects
-
Deng S, et al. (2004) Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects. Diabetes 53(3):624-632.
-
(2004)
Diabetes
, vol.53
, Issue.3
, pp. 624-632
-
-
Deng, S.1
-
8
-
-
79551600048
-
Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice
-
Lee Y, Wang MY, Du XQ, Charron MJ, Unger RH (2011) Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice. Diabetes 60(2):391-397.
-
(2011)
Diabetes
, vol.60
, Issue.2
, pp. 391-397
-
-
Lee, Y.1
Wang, M.Y.2
Du, X.Q.3
Charron, M.J.4
Unger, R.H.5
-
9
-
-
84866299596
-
Metabolic manifestations of insulin deficiency do not occur without glucagon action
-
Lee Y, et al. (2012) Metabolic manifestations of insulin deficiency do not occur without glucagon action. Proc Natl Acad Sci USA 109(37):14972-14976.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.37
, pp. 14972-14976
-
-
Lee, Y.1
-
10
-
-
84855459920
-
Glucagonocentric restructuring of diabetes: A pathophysiologic and therapeutic makeover
-
Unger RH, Cherrington AD (2012) Glucagonocentric restructuring of diabetes: A pathophysiologic and therapeutic makeover. J Clin Invest 122(1):4-12.
-
(2012)
J Clin Invest
, vol.122
, Issue.1
, pp. 4-12
-
-
Unger, R.H.1
Cherrington, A.D.2
-
11
-
-
84910156142
-
Glucagon and type 2 diabetes: The return of the alpha cell
-
Lund A, Bagger JI, Christensen M, Knop FK, Vilsbøll T (2014) Glucagon and type 2 diabetes: The return of the alpha cell. Curr Diab Rep 14(12):555.
-
(2014)
Curr Diab Rep
, vol.14
, Issue.12
, pp. 555
-
-
Lund, A.1
Bagger, J.I.2
Christensen, M.3
Knop, F.K.4
Vilsbøll, T.5
-
12
-
-
63449087896
-
Insulin signaling in alpha cells modulates glucagon secretion in vivo
-
Kawamori D, et al. (2009) Insulin signaling in alpha cells modulates glucagon secretion in vivo. Cell Metab 9(4):350-361.
-
(2009)
Cell Metab
, vol.9
, Issue.4
, pp. 350-361
-
-
Kawamori, D.1
-
13
-
-
84929954732
-
First proof of pharmacology in humans of a novel glucagon receptor antisense drug
-
van Dongen MG, et al. (2014) First proof of pharmacology in humans of a novel glucagon receptor antisense drug. J Clin Pharmacol 55 (3).
-
(2014)
J Clin Pharmacol
, vol.55
, Issue.3
-
-
Van Dongen, M.G.1
-
14
-
-
84906831104
-
Ablation of glucagon receptor signaling by peptide-based glucagon antagonists improves glucose tolerance in high fat fed mice
-
McShane LM, Franklin ZJ, O'Harte FP, Irwin N (2014) Ablation of glucagon receptor signaling by peptide-based glucagon antagonists improves glucose tolerance in high fat fed mice. Peptides 60:95-101.
-
(2014)
Peptides
, vol.60
, pp. 95-101
-
-
McShane, L.M.1
Franklin, Z.J.2
O'Harte, F.P.3
Irwin, N.4
-
15
-
-
84869805184
-
Anti-diabetic efficacy and impact on amino acid metabolism of GRA1, a novel small-molecule glucagon receptor antagonist
-
Mu J, et al. (2012) Anti-diabetic efficacy and impact on amino acid metabolism of GRA1, a novel small-molecule glucagon receptor antagonist. PLoS One 7(11):e49572.
-
(2012)
PLoS One
, vol.7
, Issue.11
, pp. e49572
-
-
Mu, J.1
-
16
-
-
0037417984
-
Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice
-
Gelling RW, et al. (2003) Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice. Proc Natl Acad Sci USA 100(3):1438-1443.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.3
, pp. 1438-1443
-
-
Gelling, R.W.1
-
17
-
-
70350666371
-
Homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, alpha cell hyperplasia, and islet cell tumor
-
Zhou C, Dhall D, Nissen NN, Chen CR, Yu R (2009) Homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, alpha cell hyperplasia, and islet cell tumor. Pancreas 38(8):941-946.
-
(2009)
Pancreas
, vol.38
, Issue.8
, pp. 941-946
-
-
Zhou, C.1
Dhall, D.2
Nissen, N.N.3
Chen, C.R.4
Yu, R.5
-
18
-
-
80755168891
-
Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice
-
Thorel F, et al. (2011) Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice. Diabetes 60(11):2872-2882.
-
(2011)
Diabetes
, vol.60
, Issue.11
, pp. 2872-2882
-
-
Thorel, F.1
-
19
-
-
84865601606
-
Glucose metabolism: Key endogenous regulator of β-cell replication and survival
-
Dadon D, et al. (2012) Glucose metabolism: Key endogenous regulator of β-cell replication and survival. Diabetes Obes Metab 14(Suppl 3):101-108.
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 101-108
-
-
Dadon, D.1
-
20
-
-
84943253417
-
Insulin demand regulates β cell number via the unfolded protein response
-
Sharma RB, et al. (2015) Insulin demand regulates β cell number via the unfolded protein response. J Clin Invest 125(10):3831-3846.
-
(2015)
J Clin Invest
, vol.125
, Issue.10
, pp. 3831-3846
-
-
Sharma, R.B.1
-
21
-
-
84937514372
-
Glucagon couples hepatic amino acid catabolism to mTOR-dependent regulation of α-cell mass
-
Solloway MJ, et al. (2015) Glucagon couples hepatic amino acid catabolism to mTOR-dependent regulation of α-cell mass. Cell Rep 12(3):495-510.
-
(2015)
Cell Rep
, vol.12
, Issue.3
, pp. 495-510
-
-
Solloway, M.J.1
-
22
-
-
84859450817
-
Angiopoietin-like 4: A decade of research
-
Zhu P, Goh YY, Chin HF, Kersten S, Tan NS (2012) Angiopoietin-like 4: A decade of research. Biosci Rep 32(3):211-219.
-
(2012)
Biosci Rep
, vol.32
, Issue.3
, pp. 211-219
-
-
Zhu, P.1
Goh, Y.Y.2
Chin, H.F.3
Kersten, S.4
Tan, N.S.5
-
23
-
-
33751213896
-
Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue
-
Sukonina V, Lookene A, Olivecrona T, Olivecrona G (2006) Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue. Proc Natl Acad Sci USA 103(46):17450-17455.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.46
, pp. 17450-17455
-
-
Sukonina, V.1
Lookene, A.2
Olivecrona, T.3
Olivecrona, G.4
-
24
-
-
4544274752
-
The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment
-
Mandard S, et al. (2004) The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment. J Biol Chem 279(33):34411-34420.
-
(2004)
J Biol Chem
, vol.279
, Issue.33
, pp. 34411-34420
-
-
Mandard, S.1
-
25
-
-
70350008227
-
Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoidregulated triglyceride metabolism
-
Koliwad SK, et al. (2009) Angiopoietin-like 4(ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoidregulated triglyceride metabolism. J Biol Chem 284(38):25593-25601.
-
(2009)
J Biol Chem
, vol.284
, Issue.38
, pp. 25593-25601
-
-
Koliwad, S.K.1
-
26
-
-
0034666157
-
Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene
-
Kersten S, et al. (2000) Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene. J Biol Chem 275(37):28488-28493.
-
(2000)
J Biol Chem
, vol.275
, Issue.37
, pp. 28488-28493
-
-
Kersten, S.1
-
27
-
-
84896532233
-
Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise
-
Catoire M, et al. (2014) Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise. Proc Natl Acad Sci USA 111(11):E1043-E1052.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.11
, pp. E1043-E1052
-
-
Catoire, M.1
-
28
-
-
13444250891
-
Inhibition of cardiac lipoprotein utilization by transgenic overexpression of Angptl4 in the heart
-
Yu X, et al. (2005) Inhibition of cardiac lipoprotein utilization by transgenic overexpression of Angptl4 in the heart. Proc Natl Acad Sci USA 102(5):1767-1772.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.5
, pp. 1767-1772
-
-
Yu, X.1
-
29
-
-
66349098389
-
Caloric restriction and exercise increase plasma ANGPTL4 levels in humans via elevated free fatty acids
-
Kersten S, et al. (2009) Caloric restriction and exercise increase plasma ANGPTL4 levels in humans via elevated free fatty acids. Arterioscler Thromb Vasc Biol 29(6):969-974.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, Issue.6
, pp. 969-974
-
-
Kersten, S.1
-
30
-
-
84950323666
-
ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure
-
Dijk W, et al. (2015) ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure. eLife 4:4.
-
(2015)
ELife
, vol.4
, pp. 4
-
-
Dijk, W.1
-
31
-
-
26844540456
-
Transgenic angiopoietin-like (angptl) 4 overexpression and targeted disruption of angptl4 and angptl3: Regulation of triglyceride metabolism
-
Köster A, et al. (2005) Transgenic angiopoietin-like (angptl) 4 overexpression and targeted disruption of angptl4 and angptl3: Regulation of triglyceride metabolism. Endocrinology 146(11):4943-4950.
-
(2005)
Endocrinology
, vol.146
, Issue.11
, pp. 4943-4950
-
-
Köster, A.1
-
32
-
-
61749090233
-
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans
-
Romeo S, et al. (2009) Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. J Clin Invest 119(1):70-79.
-
(2009)
J Clin Invest
, vol.119
, Issue.1
, pp. 70-79
-
-
Romeo, S.1
-
33
-
-
0027516035
-
Mechanism of action of des-His1-[Glu9]glucagon amide, a peptide antagonist of the glucagon receptor system
-
Post SR, Rubinstein PG, Tager HS (1993) Mechanism of action of des-His1-[Glu9]glucagon amide, a peptide antagonist of the glucagon receptor system. Proc Natl Acad Sci USA 90(5):1662-1666.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.5
, pp. 1662-1666
-
-
Post, S.R.1
Rubinstein, P.G.2
Tager, H.S.3
-
34
-
-
0024842752
-
Biological activities of des-His1[Glu9] glucagon amide, a glucagon antagonist
-
Unson CG, Gurzenda EM, Merrifield RB (1989) Biological activities of des-His1[Glu9] glucagon amide, a glucagon antagonist. Peptides 10(6):1171-1177.
-
(1989)
Peptides
, vol.10
, Issue.6
, pp. 1171-1177
-
-
Unson, C.G.1
Gurzenda, E.M.2
Merrifield, R.B.3
-
35
-
-
84862746869
-
Regulation of mouse intestinal L cell progenitors proliferation by the glucagon family of peptides
-
Grigoryan M, Kedees MH, Charron MJ, Guz Y, Teitelman G (2012) Regulation of mouse intestinal L cell progenitors proliferation by the glucagon family of peptides. Endocrinology 153(7):3076-3088.
-
(2012)
Endocrinology
, vol.153
, Issue.7
, pp. 3076-3088
-
-
Grigoryan, M.1
Kedees, M.H.2
Charron, M.J.3
Guz, Y.4
Teitelman, G.5
-
36
-
-
51349133256
-
Interleukin-6 regulates pancreatic alpha-cell mass expansion
-
Ellingsgaard H, et al. (2008) Interleukin-6 regulates pancreatic alpha-cell mass expansion. Proc Natl Acad Sci USA 105(35):13163-13168.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.35
, pp. 13163-13168
-
-
Ellingsgaard, H.1
-
37
-
-
84903447132
-
IL-6-dependent proliferation of alpha cells in mice with partial pancreatic-duct ligation
-
Cai Y, et al. (2014) IL-6-dependent proliferation of alpha cells in mice with partial pancreatic-duct ligation. Diabetologia 57(7):1420-1427.
-
(2014)
Diabetologia
, vol.57
, Issue.7
, pp. 1420-1427
-
-
Cai, Y.1
-
38
-
-
54849431792
-
The glucagon receptor is required for the adaptive metabolic response to fasting
-
Longuet C, et al. (2008) The glucagon receptor is required for the adaptive metabolic response to fasting. Cell Metab 8(5):359-371.
-
(2008)
Cell Metab
, vol.8
, Issue.5
, pp. 359-371
-
-
Longuet, C.1
-
39
-
-
79957641481
-
Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: Implications on anti-glucagon therapies for diabetes
-
Yang J, et al. (2011) Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: Implications on anti-glucagon therapies for diabetes. BMC Genomics 12:281.
-
(2011)
BMC Genomics
, vol.12
, pp. 281
-
-
Yang, J.1
-
40
-
-
84901788541
-
COMPARTMENTS: Unification and visualization of protein subcellular localization evidence
-
Binder JX, et al. (2014) COMPARTMENTS: Unification and visualization of protein subcellular localization evidence. Database (Oxford) 2014: bau012.
-
(2014)
Database (Oxford)
, vol.2014
, pp. bau012
-
-
Binder, J.X.1
-
41
-
-
84877707122
-
Betatrophin: A hormone that controls pancreatic β cell proliferation
-
Yi P, Park JS, Melton DA (2013) Betatrophin: A hormone that controls pancreatic β cell proliferation. Cell 153(4):747-758.
-
(2013)
Cell
, vol.153
, Issue.4
, pp. 747-758
-
-
Yi, P.1
Park, J.S.2
Melton, D.A.3
-
42
-
-
0028987251
-
Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model
-
Finegood DT, Scaglia L, Bonner-Weir S (1995) Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model. Diabetes 44(3):249-256.
-
(1995)
Diabetes
, vol.44
, Issue.3
, pp. 249-256
-
-
Finegood, D.T.1
Scaglia, L.2
Bonner-Weir, S.3
-
43
-
-
24144473869
-
Very slow turnover of beta-cells in aged adult mice
-
Teta M, Long SY, Wartschow LM, Rankin MM, Kushner JA (2005) Very slow turnover of beta-cells in aged adult mice. Diabetes 54(9):2557-2567.
-
(2005)
Diabetes
, vol.54
, Issue.9
, pp. 2557-2567
-
-
Teta, M.1
Long, S.Y.2
Wartschow, L.M.3
Rankin, M.M.4
Kushner, J.A.5
-
44
-
-
43849096860
-
Beneficial effects of lipids and prolactin on insulin secretion and beta-cell proliferation: A role for lipids in the adaptation of islets to pregnancy
-
Brelje TC, Bhagroo NV, Stout LE, Sorenson RL (2008) Beneficial effects of lipids and prolactin on insulin secretion and beta-cell proliferation: A role for lipids in the adaptation of islets to pregnancy. J Endocrinol 197(2):265-276.
-
(2008)
J Endocrinol
, vol.197
, Issue.2
, pp. 265-276
-
-
Brelje, T.C.1
Bhagroo, N.V.2
Stout, L.E.3
Sorenson, R.L.4
-
45
-
-
8144226856
-
The gut microbiota as an environmental factor that regulates fat storage
-
Bäckhed F, et al. (2004) The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci USA 101(44):15718-15723.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.44
, pp. 15718-15723
-
-
Bäckhed, F.1
-
46
-
-
78649499036
-
Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages
-
Lichtenstein L, et al. (2010) Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages. Cell Metab 12(6):580-592.
-
(2010)
Cell Metab
, vol.12
, Issue.6
, pp. 580-592
-
-
Lichtenstein, L.1
-
47
-
-
84865029204
-
Pancreatic beta cells in very old mice retain capacity for compensatory proliferation
-
Stolovich-Rain M, Hija A, Grimsby J, Glaser B, Dor Y (2012) Pancreatic beta cells in very old mice retain capacity for compensatory proliferation. J Biol Chem 287(33):27407-27414.
-
(2012)
J Biol Chem
, vol.287
, Issue.33
, pp. 27407-27414
-
-
Stolovich-Rain, M.1
Hija, A.2
Grimsby, J.3
Glaser, B.4
Dor, Y.5
-
48
-
-
10744230106
-
GLP-1 derivative liraglutide in rats with beta-cell deficiencies: Influence of metabolic state on beta-cell mass dynamics
-
Sturis J, et al. (2003) GLP-1 derivative liraglutide in rats with beta-cell deficiencies: Influence of metabolic state on beta-cell mass dynamics. Br J Pharmacol 140(1):123-132.
-
(2003)
Br J Pharmacol
, vol.140
, Issue.1
, pp. 123-132
-
-
Sturis, J.1
-
49
-
-
84908374200
-
Perspectives on the activities of ANGPTL8/betatrophin
-
Yi P, Park JS, Melton DA (2014) Perspectives on the activities of ANGPTL8/betatrophin. Cell 159(3):467-468.
-
(2014)
Cell
, vol.159
, Issue.3
, pp. 467-468
-
-
Yi, P.1
Park, J.S.2
Melton, D.A.3
-
50
-
-
84937525306
-
The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice
-
Spaeth JM, et al. (2015) The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice. Diabetologia 58(8):1836-1844.
-
(2015)
Diabetologia
, vol.58
, Issue.8
, pp. 1836-1844
-
-
Spaeth, J.M.1
-
51
-
-
79551532051
-
Insulin and glucagon regulate pancreatic α-cell proliferation
-
Liu Z, et al. (2011) Insulin and glucagon regulate pancreatic α-cell proliferation. PLoS One 6(1):e16096.
-
(2011)
PLoS One
, vol.6
, Issue.1
, pp. e16096
-
-
Liu, Z.1
-
52
-
-
20944447890
-
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice
-
Xu A, et al. (2005) Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. Proc Natl Acad Sci USA 102(17):6086-6091.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.17
, pp. 6086-6091
-
-
Xu, A.1
-
53
-
-
84863281947
-
Angiopoietin-like 4 (Angptl4) protein is a physiological mediator of intracellular lipolysis in murine adipocytes
-
Gray NE, et al. (2012) Angiopoietin-like 4(Angptl4) protein is a physiological mediator of intracellular lipolysis in murine adipocytes. J Biol Chem 287(11):8444-8456.
-
(2012)
J Biol Chem
, vol.287
, Issue.11
, pp. 8444-8456
-
-
Gray, N.E.1
-
54
-
-
84875478761
-
Liver-specific disruption of the murine glucagon receptor produces α-cell hyperplasia: Evidence for a circulating α-cell growth factor
-
Longuet C, et al. (2013) Liver-specific disruption of the murine glucagon receptor produces α-cell hyperplasia: Evidence for a circulating α-cell growth factor. Diabetes 62(4):1196-1205.
-
(2013)
Diabetes
, vol.62
, Issue.4
, pp. 1196-1205
-
-
Longuet, C.1
-
56
-
-
84924787149
-
Lack of glucagon receptor signaling and its implications beyond glucose homeostasis
-
Charron MJ, Vuguin PM (2015) Lack of glucagon receptor signaling and its implications beyond glucose homeostasis. J Endocrinol 224(3):R123-R130.
-
(2015)
J Endocrinol
, vol.224
, Issue.3
, pp. R123-R130
-
-
Charron, M.J.1
Vuguin, P.M.2
-
57
-
-
84939984905
-
In vivo targeted delivery of ANGPTL8 gene for beta cell regeneration in rats
-
Chen J, et al. (2015) In vivo targeted delivery of ANGPTL8 gene for beta cell regeneration in rats. Diabetologia 58(5):1036-1044.
-
(2015)
Diabetologia
, vol.58
, Issue.5
, pp. 1036-1044
-
-
Chen, J.1
-
58
-
-
84908331466
-
ANGPTL8/betatrophin does not control pancreatic beta cell expansion
-
Gusarova V, et al. (2014) ANGPTL8/betatrophin does not control pancreatic beta cell expansion. Cell 159(3):691-696.
-
(2014)
Cell
, vol.159
, Issue.3
, pp. 691-696
-
-
Gusarova, V.1
-
59
-
-
84885044818
-
Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis
-
Wang Y, et al. (2013) Mice lacking ANGPTL8(Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis. Proc Natl Acad Sci USA 110(40):16109-16114.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.40
, pp. 16109-16114
-
-
Wang, Y.1
-
60
-
-
84931566375
-
Angiopoietin-like protein 8 (ANGPTL8)/betatrophin overexpression does not increase beta cell proliferation in mice
-
Cox AR, et al. (2015) Angiopoietin-like protein 8(ANGPTL8)/betatrophin overexpression does not increase beta cell proliferation in mice. Diabetologia 58(7):1523-1531.
-
(2015)
Diabetologia
, vol.58
, Issue.7
, pp. 1523-1531
-
-
Cox, A.R.1
-
61
-
-
84864809680
-
Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels
-
Zhang R (2012) Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels. Biochem Biophys Res Commun 424(4):786-792.
-
(2012)
Biochem Biophys Res Commun
, vol.424
, Issue.4
, pp. 786-792
-
-
Zhang, R.1
-
62
-
-
84864501914
-
Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism
-
Ren G, Kim JY, Smas CM (2012) Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism. Am J Physiol Endocrinol Metab 303(3):E334-E351.
-
(2012)
Am J Physiol Endocrinol Metab
, vol.303
, Issue.3
, pp. E334-E351
-
-
Ren, G.1
Kim, J.Y.2
Smas, C.M.3
-
63
-
-
84859161516
-
Regulation of triglyceride metabolism by Angiopoietinlike proteins
-
Mattijssen F, Kersten S (2012) Regulation of triglyceride metabolism by Angiopoietinlike proteins. Biochim Biophys Acta 1821(5):782-789.
-
(2012)
Biochim Biophys Acta
, vol.1821
, Issue.5
, pp. 782-789
-
-
Mattijssen, F.1
Kersten, S.2
-
64
-
-
0036847133
-
Angiopoietin-like protein 4 is a potent hyperlipidemia-inducing factor in mice and inhibitor of lipoprotein lipase
-
Yoshida K, Shimizugawa T, Ono M, Furukawa H (2002) Angiopoietin-like protein 4 is a potent hyperlipidemia-inducing factor in mice and inhibitor of lipoprotein lipase. J Lipid Res 43(11):1770-1772.
-
(2002)
J Lipid Res
, vol.43
, Issue.11
, pp. 1770-1772
-
-
Yoshida, K.1
Shimizugawa, T.2
Ono, M.3
Furukawa, H.4
-
65
-
-
66449084528
-
A highly conserved motif within the NH2-terminal coiled-coil domain of angiopoietin-like protein 4 confers its inhibitory effects on lipoprotein lipase by disrupting the enzyme dimerization
-
Yau MH, et al. (2009) A highly conserved motif within the NH2-terminal coiled-coil domain of angiopoietin-like protein 4 confers its inhibitory effects on lipoprotein lipase by disrupting the enzyme dimerization. J Biol Chem 284(18):11942-11952.
-
(2009)
J Biol Chem
, vol.284
, Issue.18
, pp. 11942-11952
-
-
Yau, M.H.1
-
66
-
-
84857435669
-
Free fatty acids block glucose-induced β-cell proliferation in mice by inducing cell cycle inhibitors p16 and p18
-
Pascoe J, et al. (2012) Free fatty acids block glucose-induced β-cell proliferation in mice by inducing cell cycle inhibitors p16 and p18. Diabetes 61(3):632-641.
-
(2012)
Diabetes
, vol.61
, Issue.3
, pp. 632-641
-
-
Pascoe, J.1
-
67
-
-
0030759095
-
The role of non-esterified fatty acids in the deterioration of glucose tolerance in Caucasian subjects: Results of the Paris Prospective Study
-
Charles MA, et al. (1997) The role of non-esterified fatty acids in the deterioration of glucose tolerance in Caucasian subjects: Results of the Paris Prospective Study. Diabetologia 40(9):1101-1106.
-
(1997)
Diabetologia
, vol.40
, Issue.9
, pp. 1101-1106
-
-
Charles, M.A.1
-
68
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen H, et al. (1996) Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice. Cell 84(3):491-495.
-
(1996)
Cell
, vol.84
, Issue.3
, pp. 491-495
-
-
Chen, H.1
-
69
-
-
85003341559
-
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway
-
Blum B, et al. (2014) Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway. eLife 3:e02809.
-
(2014)
ELife
, vol.3
, pp. e02809
-
-
Blum, B.1
|