메뉴 건너뛰기




Volumn 57, Issue 7, 2014, Pages 1420-1427

IL-6-dependent proliferation of alpha cells in mice with partial pancreatic-duct ligation

Author keywords

Alpha cell; Beta cell; Diabetes; Glucagon; IL 6; Islet; Neogenesis; Partial duct ligation; Proliferation; Reprogramming

Indexed keywords

GLUCAGON; GLUCOSE; INTERLEUKIN 6; MONOCLONAL ANTIBODY KI 67;

EID: 84903447132     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3242-8     Document Type: Article
Times cited : (11)

References (29)
  • 1
    • 2342510386 scopus 로고    scopus 로고
    • Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
    • DOI 10.1038/nature02520
    • Dor Y, Brown J, Martinez OI, Melton DA (2004) Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429:41-46 (Pubitemid 38620543)
    • (2004) Nature , vol.429 , Issue.6987 , pp. 41-46
    • Dor, Y.1    Brown, J.2    Martinez, O.I.3    Melton, D.A.4
  • 2
    • 34848887156 scopus 로고    scopus 로고
    • Recovery from diabetes in mice by β cell regeneration
    • DOI 10.1172/JCI32959
    • Nir T, Melton DA, Dor Y (2007) Recovery from diabetes in mice by β cell regeneration. J Clin Invest 117:2553-2561 (Pubitemid 47494356)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.9 , pp. 2553-2561
    • Nir, T.1    Melton, D.A.2    Dor, Y.3
  • 3
    • 34247644369 scopus 로고    scopus 로고
    • Growth and Regeneration of Adult β Cells Does Not Involve Specialized Progenitors
    • DOI 10.1016/j.devcel.2007.04.011, PII S153458070700158X
    • Teta M, Rankin MM, Long SY et al (2007) Growth and regeneration of adult β cells does not involve specialized progenitors. Dev Cell 12: 817-826 (Pubitemid 46667754)
    • (2007) Developmental Cell , vol.12 , Issue.5 , pp. 817-826
    • Teta, M.1    Rankin, M.M.2    Long, S.Y.3    Stein, G.M.4    Kushner, J.A.5
  • 4
    • 53349178722 scopus 로고    scopus 로고
    • In vivo reprogramming of adult pancreatic exocrine cells to β-cells
    • Zhou Q, Brown J, Kanarek A et al (2008) In vivo reprogramming of adult pancreatic exocrine cells to β-cells. Nature 455:627-632
    • (2008) Nature , vol.455 , pp. 627-632
    • Zhou, Q.1    Brown, J.2    Kanarek, A.3
  • 6
    • 84873111871 scopus 로고    scopus 로고
    • Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration
    • Pan FC, Bankaitis ED, Boyer D et al (2013) Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration. Development 140:751-764
    • (2013) Development , vol.140 , pp. 751-764
    • Pan, F.C.1    Bankaitis, E.D.2    Boyer, D.3
  • 7
    • 68149162957 scopus 로고    scopus 로고
    • The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha- and subsequently beta cells
    • Collombat P, Xu X, Ravassard P et al (2009) The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha- and subsequently beta cells. Cell 138:449-462
    • (2009) Cell , vol.138 , pp. 449-462
    • Collombat, P.1    Xu, X.2    Ravassard, P.3
  • 8
    • 84880506680 scopus 로고    scopus 로고
    • Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes
    • Al-Hasani K, Pfeifer A, Courtney M et al (2013) Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes. Dev Cell 26:86-100
    • (2013) Dev Cell , vol.26 , pp. 86-100
    • Al-Hasani, K.1    Pfeifer, A.2    Courtney, M.3
  • 9
    • 77951611220 scopus 로고    scopus 로고
    • Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss
    • Thorel F, Népote V, Avril I et al (2010) Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss. Nature 464:1149-1154
    • (2010) Nature , vol.464 , pp. 1149-1154
    • Thorel, F.1    Népote, V.2    Avril, I.3
  • 10
    • 84864401274 scopus 로고    scopus 로고
    • α-Cell role in β-cell generation and regeneration
    • Habener JF, Stanojevic V (2012) α-Cell role in β-cell generation and regeneration. Islets 4:188-198
    • (2012) Islets , vol.4 , pp. 188-198
    • Habener, J.F.1    Stanojevic, V.2
  • 12
    • 84875910312 scopus 로고    scopus 로고
    • Neurogenin 3(+) cells contribute to β-cell neogenesis and proliferation in injured adult mouse pancreas
    • Van de Casteele M, Leuckx G, Baeyens L et al (2013) Neurogenin 3(+) cells contribute to β-cell neogenesis and proliferation in injured adult mouse pancreas. Cell Death Dis 4:e523
    • (2013) Cell Death Dis , vol.4
    • Van De Casteele, M.1    Leuckx, G.2    Baeyens, L.3
  • 13
    • 78651228289 scopus 로고    scopus 로고
    • Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
    • Furuyama K, Kawaguchi Y, Akiyama H et al (2010) Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet 43:34-41
    • (2010) Nat Genet , vol.43 , pp. 34-41
    • Furuyama, K.1    Kawaguchi, Y.2    Akiyama, H.3
  • 14
    • 0028793314 scopus 로고
    • Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats
    • Wang RN, Klöppel G, Bouwens L (1995) Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats. Diabetologia 38:1405-1411
    • (1995) Diabetologia , vol.38 , pp. 1405-1411
    • Wang, R.N.1    Klöppel, G.2    Bouwens, L.3
  • 15
    • 84876579681 scopus 로고    scopus 로고
    • Beta cells are not generated in pancreatic duct ligation induced injury in adult mice
    • Rankin MM, Wilbur CJ, Rak K et al (2013) Beta cells are not generated in pancreatic duct ligation induced injury in adult mice. Diabetes 62:1634-1645
    • (2013) Diabetes , vol.62 , pp. 1634-1645
    • Rankin, M.M.1    Wilbur, C.J.2    Rak, K.3
  • 16
    • 84875452820 scopus 로고    scopus 로고
    • No evidence for β cell neogenesis in murine adult pancreas
    • Xiao X, Chen Z, Shiota C et al (2013) No evidence for β cell neogenesis in murine adult pancreas. J Clin Invest 123:2207-2217
    • (2013) J Clin Invest , vol.123 , pp. 2207-2217
    • Xiao, X.1    Chen, Z.2    Shiota, C.3
  • 18
    • 51349133256 scopus 로고    scopus 로고
    • Interleukin-6 regulates pancreatic alpha-cell mass expansion
    • Ellingsgaard H, Ehses JA, Hammar EB et al (2008) Interleukin-6 regulates pancreatic alpha-cell mass expansion. Proc Natl Acad Sci U S A 105:13163-13168
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 13163-13168
    • Ellingsgaard, H.1    Ehses, J.A.2    Hammar, E.B.3
  • 19
    • 77953212007 scopus 로고    scopus 로고
    • Ectopic expression of E2F1 stimulates beta-cell proliferation and function
    • Grouwels G, Cai Y, Hoebeke I et al (2010) Ectopic expression of E2F1 stimulates beta-cell proliferation and function. Diabetes 59: 1435-1444
    • (2010) Diabetes , vol.59 , pp. 1435-1444
    • Grouwels, G.1    Cai, Y.2    Hoebeke, I.3
  • 20
    • 0025610846 scopus 로고
    • Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice
    • Starnes HF, Pearce MK, Tewari A et al (1990) Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice. J Immunol 145:4185-4191
    • (1990) J Immunol , vol.145 , pp. 4185-4191
    • Starnes, H.F.1    Pearce, M.K.2    Tewari, A.3
  • 21
    • 3042856262 scopus 로고    scopus 로고
    • Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
    • Srinivas S, Watanabe T, Lin CS et al (2001) Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol 1:4
    • (2001) BMC Dev Biol , vol.1 , pp. 4
    • Srinivas, S.1    Watanabe, T.2    Lin, C.S.3
  • 22
    • 0031898957 scopus 로고    scopus 로고
    • Mouse pancreatic beta-cells exhibit preserved glucose competence after disruption of the glucagon-like peptide-1 receptor gene
    • DOI 10.2337/diabetes.47.4.646
    • Flamez D, Van Breusegem A, Scrocchi LA et al (1998) Mouse pancreatic beta-cells exhibit preserved glucose competence after disruption of the glucagon-like peptide-1 receptor gene. Diabetes 47:646-652 (Pubitemid 28160457)
    • (1998) Diabetes , vol.47 , Issue.4 , pp. 646-652
    • Flamez, D.1    Van Breusegem, A.2    Scrocchi, L.A.3    Quartier, E.4    Pipeleers, D.5    Drucker, D.J.6    Schuit, F.7
  • 23
    • 0033710733 scopus 로고    scopus 로고
    • p53-dependent acinar cell apoptosis triggers epithelial proliferation in duct-ligated murine pancreas
    • Scoggins CR, Meszoely IM, Wada M et al (2000) p53-dependent acinar cell apoptosis triggers epithelial proliferation in duct-ligated murine pancreas. Am J Physiol Gastrointest Liver Physiol 279: G827-G836
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.279
    • Scoggins, C.R.1    Meszoely, I.M.2    Wada, M.3
  • 24
    • 84866389264 scopus 로고    scopus 로고
    • Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure
    • Talchai C, Xuan S, Lin HV et al (2012) Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure. Cell 150:1223-1234
    • (2012) Cell , vol.150 , pp. 1223-1234
    • Talchai, C.1    Xuan, S.2    Lin, H.V.3
  • 25
    • 72449156523 scopus 로고    scopus 로고
    • Single pancreatic beta cells co-express multiple islet hormone genes in mice
    • Katsuta H, Akashi T, Katsuta R et al (2009) Single pancreatic beta cells co-express multiple islet hormone genes in mice. Diabetologia 53:128-138
    • (2009) Diabetologia , vol.53 , pp. 128-138
    • Katsuta, H.1    Akashi, T.2    Katsuta, R.3
  • 27
    • 84883722508 scopus 로고    scopus 로고
    • Conversion of mature human β-cells into glucagon-producing α-cells
    • Spijker HS, Ravelli RBG, Mommaas-Kienhuis AM et al (2013) Conversion of mature human β-cells into glucagon-producing α-cells. Diabetes 62:2471-2480
    • (2013) Diabetes , vol.62 , pp. 2471-2480
    • Spijker, H.S.1    Ravelli, R.B.G.2    Mommaas-Kienhuis, A.M.3
  • 28
    • 84875479006 scopus 로고    scopus 로고
    • TGFβ receptor signaling is essential for inflammation-induced but not β-cell workload-induced β-cell proliferation
    • Xiao X, Wiersch J, El-Gohary Y et al (2012) TGFβ receptor signaling is essential for inflammation-induced but not β-cell workload-induced β-cell proliferation. Diabetes 62:1217-1226
    • (2012) Diabetes , vol.62 , pp. 1217-1226
    • Xiao, X.1    Wiersch, J.2    El-Gohary, Y.3
  • 29
    • 81255157471 scopus 로고    scopus 로고
    • Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
    • Ellingsgaard H, Hauselmann I, Schuler B et al (2011) Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat Med 17:1481-1489
    • (2011) Nat Med , vol.17 , pp. 1481-1489
    • Ellingsgaard, H.1    Hauselmann, I.2    Schuler, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.