메뉴 건너뛰기




Volumn 45, Issue 6, 2015, Pages 692-701

NUT midline carcinoma: Morphoproteomic characterization with genomic and therapeutic correlates

Author keywords

Biomedical analytics; C Myc; EZH2; Morphoproteomic; MTORC2 pathway; NUT midline carcinoma; Sirt1

Indexed keywords

ANTIBODY; CURCUMIN; HISTONE METHYLTRANSFERASE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MELATONIN; METFORMIN; SIRTUIN 1; SOMATOMEDIN C RECEPTOR; SULFORAPHANE; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR SOX2; VORINOSTAT; EZH2 PROTEIN, HUMAN; ISOTHIOCYANIC ACID DERIVATIVE; MTOR PROTEIN, HUMAN; NUCLEAR PROTEIN; NUT PROTEIN, HUMAN; ONCOPROTEIN; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN KINASE B; SIRT1 PROTEIN, HUMAN; SULFORAFAN; TARGET OF RAPAMYCIN KINASE;

EID: 84950249972     PISSN: 00917370     EISSN: 15508080     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (9)

References (51)
  • 5
    • 79951515876 scopus 로고    scopus 로고
    • A review of NUT midline carcinoma
    • Stelow EB. A review of NUT midline carcinoma. Head Neck Pathol 2011;5:31-35.
    • (2011) Head Neck Pathol , vol.5 , pp. 31-35
    • Stelow, E.B.1
  • 7
    • 84874973263 scopus 로고    scopus 로고
    • The importance of diagnosing NUT midline carcinoma
    • French CA. The importance of diagnosing NUT midline carcinoma. Head Neck Pathol 2013;7:11-16.
    • (2013) Head Neck Pathol , vol.7 , pp. 11-16
    • French, C.A.1
  • 10
    • 84856857218 scopus 로고    scopus 로고
    • Pathogenesis of NUT midline carcinoma
    • French CA. Pathogenesis of NUT midline carcinoma. Annu Rev Pathol 2012;7:247-265.
    • (2012) Annu Rev Pathol , vol.7 , pp. 247-265
    • French, C.A.1
  • 12
    • 0041806599 scopus 로고    scopus 로고
    • The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis
    • Dey A, Chitsaz F, Abbasi A, Misteli T, Ozato K. The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis. Proc Natl Acad Sci U S A 2003;100:8758-8763.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8758-8763
    • Dey, A.1    Chitsaz, F.2    Abbasi, A.3    Misteli, T.4    Ozato, K.5
  • 16
    • 20544477463 scopus 로고    scopus 로고
    • Morphoproteomics: exposing protein circuitries in tumors to identify potential therapeutic targets in cancer patients
    • Brown RE. Morphoproteomics: exposing protein circuitries in tumors to identify potential therapeutic targets in cancer patients. Expert Rev Proteomics 2005;2:337-348.
    • (2005) Expert Rev Proteomics , vol.2 , pp. 337-348
    • Brown, R.E.1
  • 17
    • 64849109415 scopus 로고    scopus 로고
    • Morphogenomics and morphoproteomics: a role for anatomic pathology in personalized medicine
    • Brown RE. Morphogenomics and morphoproteomics: a role for anatomic pathology in personalized medicine. Arch Pathol Lab Med 2009;133:568-579.
    • (2009) Arch Pathol Lab Med , vol.133 , pp. 568-579
    • Brown, R.E.1
  • 18
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • Wullschleger S, Loewith R, Hall MN. TOR signaling in growth and metabolism. Cell 2006;124:471-484.
    • (2006) Cell , vol.124 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 19
    • 34047095297 scopus 로고    scopus 로고
    • The two TORCs and Akt
    • Bhaskar PT, Hay N. The two TORCs and Akt. Dev Cell 2007;12:487-502.
    • (2007) Dev Cell , vol.12 , pp. 487-502
    • Bhaskar, P.T.1    Hay, N.2
  • 20
    • 34347220473 scopus 로고    scopus 로고
    • Defining the role of mTOR in cancer
    • Guertin DA, Sabatini DM. Defining the role of mTOR in cancer. Cancer Cell 2007;12:9-22.
    • (2007) Cancer Cell , vol.12 , pp. 9-22
    • Guertin, D.A.1    Sabatini, D.M.2
  • 21
    • 84896700981 scopus 로고    scopus 로고
    • Branched chain amino acid suppresses hepatocellular cancer stem cells through the activation of mammalian target of rapamycin
    • Nishitani S, Horie M, Ishizaki S, Yano H. Branched chain amino acid suppresses hepatocellular cancer stem cells through the activation of mammalian target of rapamycin. PLoS One 2013;8:e82346.
    • (2013) PLoS One , vol.8
    • Nishitani, S.1    Horie, M.2    Ishizaki, S.3    Yano, H.4
  • 22
    • 84890152601 scopus 로고    scopus 로고
    • Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1
    • Francipane MG, Lagasse E. Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1. Oncotarget 2013;4:1948-1962.
    • (2013) Oncotarget , vol.4 , pp. 1948-1962
    • Francipane, M.G.1    Lagasse, E.2
  • 23
    • 84890718769 scopus 로고    scopus 로고
    • Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway
    • Lee KS, Wu Z, Song Y, Mitra SS, Feroze AH, Cheshier SH, Lu B. Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway. Genes Dev 2013;27:2642-2647.
    • (2013) Genes Dev , vol.27 , pp. 2642-2647
    • Lee, K.S.1    Wu, Z.2    Song, Y.3    Mitra, S.S.4    Feroze, A.H.5    Cheshier, S.H.6    Lu, B.7
  • 25
    • 52949137425 scopus 로고    scopus 로고
    • Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1
    • Rosner M, Hengstschläger M. Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1. Hum Mol Genet. 2008;17:2934-2948.
    • (2008) Hum Mol Genet , vol.17 , pp. 2934-2948
    • Rosner, M.1    Hengstschläger, M.2
  • 26
    • 28844434558 scopus 로고    scopus 로고
    • mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes
    • Hresko RC, Mueckler M. mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes. J Biol Chem. 2005;280:40406-40416.
    • (2005) J Biol Chem , vol.280 , pp. 40406-40416
    • Hresko, R.C.1    Mueckler, M.2
  • 27
    • 77955770568 scopus 로고    scopus 로고
    • Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells
    • Zakikhani M, Blouin MJ, Piura E, Pollak MN. Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells. Breast Cancer Res Treat. 2010;123:271-279.
    • (2010) Breast Cancer Res Treat , vol.123 , pp. 271-279
    • Zakikhani, M.1    Blouin, M.J.2    Piura, E.3    Pollak, M.N.4
  • 28
    • 80054782483 scopus 로고    scopus 로고
    • The dual role of sirtuins in cancer
    • Bosch-Presegué L, Vaquero A. The dual role of sirtuins in cancer. Genes Cancer 2011;2:648-662.
    • (2011) Genes Cancer , vol.2 , pp. 648-662
    • Bosch-Presegué, L.1    Vaquero, A.2
  • 30
    • 84867380741 scopus 로고    scopus 로고
    • Janus-faced role of SIRT1 in tumorigenesis
    • Song NY, Surh YJ. Janus-faced role of SIRT1 in tumorigenesis. Ann N Y Acad Sci 2012;1271:10-19.
    • (2012) Ann N Y Acad Sci , vol.1271 , pp. 10-19
    • Song, N.Y.1    Surh, Y.J.2
  • 34
    • 84856466661 scopus 로고    scopus 로고
    • The role of EZH2 in tumour progression
    • Chang CJ, Hung MC. The role of EZH2 in tumour progression. Br J Cancer 2012;106:243-247.
    • (2012) Br J Cancer , vol.106 , pp. 243-247
    • Chang, C.J.1    Hung, M.C.2
  • 37
    • 15444377466 scopus 로고    scopus 로고
    • SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain
    • Bouras T, Fu M, Sauve AA, Wang F, Quong AA, Perkins ND, Hay RT, Gu W, Pestell RG. SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain.J Biol Chem 2005;280:10264-10276.
    • (2005) J Biol Chem , vol.280 , pp. 10264-10276
    • Bouras, T.1    Fu, M.2    Sauve, A.A.3    Wang, F.4    Quong, A.A.5    Perkins, N.D.6    Hay, R.T.7    Gu, W.8    Pestell, R.G.9
  • 44
    • 79960391940 scopus 로고    scopus 로고
    • miR-200a regulates SIRT1 expression and epithelial to mesenchymal transition (EMT)-like transformation in mammary epithelial cells
    • Eades G, Yao Y, Yang M, Zhang Y, Chumsri S, Zhou Q. miR-200a regulates SIRT1 expression and epithelial to mesenchymal transition (EMT)-like transformation in mammary epithelial cells. J Biol Chem. 2011;286(29):25992-26002.
    • (2011) J Biol Chem , vol.286 , Issue.29 , pp. 25992-26002
    • Eades, G.1    Yao, Y.2    Yang, M.3    Zhang, Y.4    Chumsri, S.5    Zhou, Q.6
  • 45
    • 84877267617 scopus 로고    scopus 로고
    • Defining the role of histone deacetylases in the inhibition of mammary carcinogenesis by dietary energy restriction (DER): effects of suberoylanilide hydroxamic acid (SAHA) and DER in a rat model
    • Zhu Z, Jiang W, McGinley JN, Thompson HJ. Defining the role of histone deacetylases in the inhibition of mammary carcinogenesis by dietary energy restriction (DER): effects of suberoylanilide hydroxamic acid (SAHA) and DER in a rat model. Cancer Prev Res (Phila). 2013;6:290-298.
    • (2013) Cancer Prev Res (Phila) , vol.6 , pp. 290-298
    • Zhu, Z.1    Jiang, W.2    McGinley, J.N.3    Thompson, H.J.4
  • 46
    • 21644464967 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor suberoylanilide hydroxamic acid downregulates expression levels of Bcr-abl, c-Myc and HDAC3 in chronic myeloid leukemia cell lines
    • Xu Y, Voelter-Mahlknecht S, Mahlknecht U. The histone deacetylase inhibitor suberoylanilide hydroxamic acid downregulates expression levels of Bcr-abl, c-Myc and HDAC3 in chronic myeloid leukemia cell lines. Int J Mol Med. 2005;15:169-172.
    • (2005) Int J Mol Med , vol.15 , pp. 169-172
    • Xu, Y.1    Voelter-Mahlknecht, S.2    Mahlknecht, U.3
  • 47
    • 84872172430 scopus 로고    scopus 로고
    • Vorinostat induces apoptosis and differentiation in myeloid malignancies: genetic and molecular mechanisms
    • Silva G, Cardoso BA, Belo H, Almeida AM. Vorinostat induces apoptosis and differentiation in myeloid malignancies: genetic and molecular mechanisms. PLoS One. 2013;8:e53766.
    • (2013) PLoS One , vol.8
    • Silva, G.1    Cardoso, B.A.2    Belo, H.3    Almeida, A.M.4
  • 50
    • 80052527908 scopus 로고    scopus 로고
    • The mechanism of action of the histone deacetylase inhibitor vorinostat involves interaction with the insulin-like growth factor signaling pathway
    • Sarfstein R, Bruchim I, Fishman A, Werner H. The mechanism of action of the histone deacetylase inhibitor vorinostat involves interaction with the insulin-like growth factor signaling pathway. PLoS One 2011;6:e24468.
    • (2011) PLoS One , vol.6
    • Sarfstein, R.1    Bruchim, I.2    Fishman, A.3    Werner, H.4
  • 51
    • 84871822817 scopus 로고    scopus 로고
    • Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model
    • Kurundkar D, Srivastava RK, Chaudhary SC, Ballestas ME, Kopelovich L, Elmets CA, Athar M. Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model. Toxicol Appl Pharmacol 2013;266:233-244.
    • (2013) Toxicol Appl Pharmacol , vol.266 , pp. 233-244
    • Kurundkar, D.1    Srivastava, R.K.2    Chaudhary, S.C.3    Ballestas, M.E.4    Kopelovich, L.5    Elmets, C.A.6    Athar, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.