Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway

Genes and Development

Volumn 27, Issue 24, 2013, Pages 2642-2647

  Lee, Kyu Sun ^a,b   Wu, Zhihao ^a   Song, Yan ^a,c   Mitra, Siddhartha S ^a   Feroze, Abdullah H ^a   Cheshier, Samuel H ^a   Lu, Bingwei ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c PEKING UNIVERSITY   (China)

Author keywords

Cancer stem cells; Mitochondria; mTORC2 AKT signaling; Neural stem cells; Notch; PINK1

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PTEN INDUCED KINASE 1; UNCLASSIFIED DRUG;

ARTICLE; BRAIN TUMOR; CANCER STEM CELL; DROSOPHILA; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; STEM CELL;

CANCER STEM CELLS; MITOCHONDRIA; MTORC2/AKT SIGNALING; NEURAL STEM CELLS; NOTCH; PINK1;

ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MULTIPROTEIN COMPLEXES; MUTATION; NEOPLASTIC STEM CELLS; PROTEIN KINASES; RECEPTORS, NOTCH; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84890718769     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.225169.113     Document Type: Article

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