Evaluation of the versatile character of a nanoemulsion formulation

International Journal of Pharmaceutics

Volumn 498, Issue 1-2, 2016, Pages 49-65

  Gue E ^a,b   Since, M ^a,b   Ropars, S ^a,b   Herbinet, R ^a   Le Pluart, L ^a   Malzert Freon A ^a,b  

^a UNIVERSITÉ DE CAEN   (France)

^b CENTRE D ETUDES ET DE RECHERCHE SUR LE MÉDICAMENT DE NORMANDIE   (France)

Author keywords

Apparent solubility; Labrasol ; Nanoemulsion; Parenteral administration; Self emulsification

Indexed keywords

AMIODARONE; CIPROFLOXACIN; EXCIPIENT; FENOFIBRATE; IBUPROFEN; NONIONIC SURFACTANT; PARACETAMOL; PHOSPHATE; RANITIDINE; TRIACYLGLYCEROL; ACYLGLYCEROL; EMULSION; LABRASOL; NANOPARTICLE; SURFACTANT;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; NANOEMULSION; OSMOLARITY; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; ROOM TEMPERATURE; ZETA POTENTIAL; CHEMISTRY; EMULSION; MEDICINAL CHEMISTRY; METABOLISM; PRECLINICAL STUDY; PROCEDURES;

CHEMISTRY, PHARMACEUTICAL; DRUG EVALUATION, PRECLINICAL; EMULSIONS; GLYCERIDES; NANOPARTICLES; SURFACE-ACTIVE AGENTS;

EID: 84950150811     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.12.010     Document Type: Article

References (69)

1. M. Allwood, and H. Martin Factors influencing the stability of ranitidine in TPN mixtures Clin. Nutr. 14 1995 171 176
2. G.L. Amidon, H. Lennernäs, V.P. Shah, and J.R. Crison A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability Pharm. Res. 12 1995 413 420
3. N. Anton, and T.F. Vandamme The universality of low-energy nano-emulsification Int. J. Pharm. 377 2009 142 147
4. N. Anton, and T. Vandamme Nano-emulsions and micro-emulsions: clarifications of the critical differences Pharm. Res. 28 2011 978 985
5. N. Anton, J.P. Benoit, and P. Saulnier Design and production of nanoparticles formulated from nano-emulsion templates-a review J. Controlled Release 128 2008 185 199
6. A. Avdeef Absorption and Drug Development: Solubility, Permeability, and Charge State 2012 John Wiley & Sons ed.
7. C.Y. Botté, F. Dubar, G.I. McFadden, E. Maréchal, and C. Biot Plasmodium falciparum apicoplast drugs: targets or off-targets? Chem. Rev. 112 2011 1269 1283
8. Y. Bouligand, F. Boury, J.M. Devoisselle, R. Fortune, J.C. Gautier, D. Girard, H. Maillol, and J.E. Proust Liquid crystals and colloids in water-amiodarone systems Langmuir 14 1998 542 546
9. F. Boury, J.C. Gautier, Y. Bouligand, and J.E. Proust Interfacial properties of amiodarone: the stabilizing effect of phosphate anions Colloids Surf. B 20 2001 219 227
10. Y. Chang, L. McLandsborough, and D.J. McClements Physicochemical properties and antimicrobial efficacy of carvacrol nanoemulsions formed by spontaneous emulsification J. Agric. Food Chem. 61 2013 8906 8913
11. X.Q. Chen, O.S. Gudmundsson, and M.J. Hageman Application of lipid-based formulations in drug discovery J. Med. Chem. 55 2012 7945 7956
12. H. Choudhury, B. Gorain, S. Karmakar, E. Biswas, G. Dey, R. Barik, M. Mandal, and T.K. Pal Improvement of cellular uptake, in vitro antitumor activity and sustained release profile with increased bioavailability from a nanoemulsion platform Int. J. Pharm. 460 2014 131 143
13. P.P. Constantinides, M.V. Chaubal, and R. Shorr Advances in lipid nanodispersions for parenteral drug delivery and targeting Adv. Drug Deliv. Rev. 60 2008 757 767
14. W.G. Dai, L.C. Dong, S. Li, C. Pollock-Dove, J. Chen, P. Mansky, and G. Eichenbaum Parallel screening approach to identify solubility-enhancing formulations for improved bioavailability of a poorly water-soluble compound using milligram quantities of material Int. J. Pharm. 336 2007 1 11
15. S. Davis, L. Ilium, S. Moghimi, M. Davies, C. Porter, I. Muir, A. Brindley, N. Christy, M. Norman, and P. Williams Microspheres for targeting drugs to specific body sites J. Controlled Release 24 1993 157 163
16. M.M. de Villiers, P. Aramwit, G.S. Kwon, J.P. Fast, and S. Mecozzi Nanoemulsions for Intravenous Drug Delivery, Nanotechnology in Drug Delivery 2009 Springer New York 461 489
17. L. Djekic, M. Primorac, S. Filipic, and D. Agbaba Investigation of surfactant/cosurfactant synergism impact on ibuprofen solubilization capacity and drug release characteristics of nonionic microemulsions Int. J. Pharm. 433 2012 25 33
18. A. Elgart, I. Cherniakov, Y. Aldouby, A.J. Domb, and A. Hoffman Improved oral bioavailability of BCS class 2 compounds by self nano-emulsifying drug delivery systems (SNEDDS): the underlying mechanisms for amiodarone and talinolol Pharm. Res. 30 2013 3029 3044
19. European Pharmacopeia, 8th ed., 2016.
20. A. Forgiarini, J. Esquena, C. Gonzalez, and C. Solans Formation of nano-emulsions by low-energy emulsification methods at constant temperature Langmuir 17 2001 2076 2083
21. G. Fricker, T. Kromp, A. Wendel, A. Blume, J. Zirkel, H. Rebmann, C. Setzer, R.-O. Quinkert, F. Martin, and C. Müller-Goymann Phospholipids and lipid-based formulations in oral drug delivery Pharm. Res. 27 2010 1469 1486
22. M. Gallarate, D. Chirio, R. Bussano, E. Peira, L. Battaglia, F. Baratta, and M. Trotta Development of O/W nanoemulsions for ophthalmic administration of timolol Int. J. Pharm. 440 2013 126 134
23. L.C. Garzón, and F. Martínez Temperature dependence of solubility for ibuprofen in some organic and aqueous solvents J. Solution Chem. 33 2004 1379 1395
24. B.T. Griffin, M. Kuentz, M. Vertzoni, E.S. Kostewicz, Y. Fei, W. Faisal, C. Stillhart, C.M. O'Driscoll, C. Reppas, and J.B. Dressman Comparison of in vitro tests at various levels of complexity for the prediction of in vivo performance of lipid-based formulations: case studies with fenofibrate Eur. J. Pharm. Biopharm. 86 2014 427 437
25. E. Gue, J.F. Willart, S. Muschert, F. Danede, E. Delcourt, M. Descamps, and J. Siepmann Accelerated ketoprofen release from polymeric matrices: importance of the homogeneity/heterogeneity of excipient distribution Int. J. Pharm. 457 2013 298 307
26. F. Hallouard, S. Briançon, N. Anton, X. Li, T. Vandamme, and H. Fessi Iodinated nano-emulsions as contrast agents for preclinical X-ray imaging: impact of the free surfactants on the pharmacokinetics Eur. J. Pharm. Biopharm. 83 2013 54 62
27. L. Kalantzi, C. Reppas, J. Dressman, G. Amidon, H. Junginger, K. Midha, V. Shah, S. Stavchansky, and D.M. Barends Biowaiver monographs for immediate release solid oral dosage forms: acetaminophen (paracetamol) J. Pharm. Sci. 95 2006 4 14
28. R.G. Kelmann, G. Kuminek, H.F. Teixeira, and L.S. Koester Carbamazepine parenteral nanoemulsions prepared by spontaneous emulsification process Int. J. Pharm. 342 2007 231 239
29. H. Kortejärvi, M. Yliperttula, J. Dressman, H. Junginger, K. Midha, V. Shah, and D. Barends Biowaiver monographs for immediate release solid oral dosage forms: ranitidine hydrochloride J. Pharm. Sci. 94 2005 1617 1625
30. S. Kotta, A.W. Khan, S.H. Ansari, R.K. Sharma, and J. Ali Anti HIV nanoemulsion formulation: optimization and in vitro-in vivo evaluation Int. J. Pharm. 462 2014 129 134
31. M. Kreilgaard, E.J. Pedersen, and J.W. Jaroszewski NMR characterisation and transdermal drug delivery potential of microemulsion systems J. Controlled Release 69 2000 421 433
32. J. Kreuter Chapter 5 - Nanoparticles J. Kreuter, Colloidal Drug Delivery Systems 1994 Marcel Dekker, Inc. 219 342
33. M. Kumar, A. Misra, A. Babbar, A. Mishra, P. Mishra, and K. Pathak Intranasal nanoemulsion based brain targeting drug delivery system of risperidone Int. J. Pharm. 358 2008 285 291
34. S.V. Kurkov, and T. Loftsson Cyclodextrins Int. J. Pharm. 453 2013 167 180
35. A. Lamprecht, Y. Bouligand, and J.P. Benoit New lipid nanocapsules exhibit sustained release properties for amiodarone J. Controlled Release 84 2002 59 68
36. M.J. Lawrence, and G.D. Rees Microemulsion-based media as novel drug delivery systems Adv. Drug Delivery Rev. 45 2000 89 121
37. P. Li, and L. Zhao Developing early formulations: practice and perspective Int. J. Pharm. 341 2007 1 19
38. D.B. Mahmoud, M.H. Shukr, and E.R. Bendas In vitro and in vivo evaluation of self-nanoemulsifying drug delivery systems of cilostazol for oral and parenteral administration Int. J. Pharm. 476 2014 60 69
39. A. Malzert-Fréon, S. Vrignaud, P. Saulnier, V. Lisowski, J.P. Benoit, and S. Rault Formulation of sustained release nanoparticles loaded with a tripentone, a new anticancer agent Int. J. Pharm. 320 2006 157 164
40. A. Malzert-Fréon, G. Saint-Lorant, D. Hennequin, P. Gauduchon, L. Poulain, and S. Rault Influence of the introduction of a solubility enhancer on the formulation of lipidic nanoparticles with improved drug loading rates Eur. J. Pharm. Biopharm. 75 2010 117 127
41. D. Morales, J.M. Gutiérrez, M. Garcia-Celma, and Y. Solans A study of the relation between bicontinuous microemulsions and oil/water nano-emulsion formation Langmuir 19 2003 7196 7200
42. L. Mu, T. Elbayoumi, and V. Torchilin Mixed micelles made of poly (ethylene glycol)-phosphatidylethanolamine conjugate and d-α-tocopheryl polyethylene glycol 1000 succinate as pharmaceutical nanocarriers for camptothecin Int. J. Pharm. 306 2005 142 149
43. H. Mu, R. Holm, and A. Müllertz Lipid-based formulations for oral administration of poorly water-soluble drugs Int. J. Pharm. 453 2013 215 224
44. M. Nasr, S. Nawaz, and A. Elhissi Amphotericin B lipid nanoemulsion aerosols for targeting peripheral respiratory airways via nebulization Int. J. Pharm. 436 2012 611 616
45. Y.R. Neupane, M. Srivastava, N. Ahmad, N. Kumar, A. Bhatnagar, and K. Kohli Lipid based nanocarrier system for the potential oral delivery of decitabine: formulation design, characterization, ex vivo, and in vivo assessment Int. J. Pharm. 477 2014 601 612
46. C. O'driscoll, and B. Griffin Biopharmaceutical challenges associated with drugs with low aqueous solubility - the potential impact of lipid-based formulations Adv. Drug Delivery Rev. 60 2008 617 624
47. M. Olivera, R. Manzo, H. Junginger, K. Midha, V. Shah, S. Stavchansky, J. Dressman, and D. Barends Biowaiver monographs for immediate release solid oral dosage forms: ciprofloxacin hydrochloride J. Pharm. Sci. 100 2011 22 33
48. K.M. Park, and C.K. Kim Preparation and evaluation of flurbiprofen-loaded microemulsion for parenteral delivery Int. J. Pharm. 181 1999 173 179
49. A.R. Patel, and P.R. Vavia Preparation and in vivo evaluation of SMEDDS (self-microemulsifying drug delivery system) containing fenofibrate AAPS J. 9 2007 E344 E352
50. C.H. Porter, H. Williams, and N. Trevaskis Recent advances in lipid-based formulation technology Pharm. Res. 30 2013 2971 2975
51. H. Potthast, J. Dressman, H. Junginger, K. Midha, H. Oeser, V. Shah, H. Vogelpoel, and D. Barends Biowaiver monographs for immediate release solid oral dosage forms: Ibuprofen J. Pharm. Sci. 94 2005 2121 2131
52. C.W. Pouton Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and 'self-microemulsifying'drug delivery systems Eur. J. Pharm. Sci. 11 2000 S93 S98
53. C.W. Pouton, and C.J. Porter Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies Adv. Drug Delivery Rev. 60 2008 625 637
54. H. Ragelle, S. Crauste-Manciet, J. Seguin, D. Brossard, D. Scherman, P. Arnaud, and G.G. Chabot Nanoemulsion formulation of fisetin improves bioavailability and antitumour activity in mice Int. J. Pharm. 427 2012 452 459
55. S.S. Rane, and B.D. Anderson What determines drug solubility in lipid vehicles: is it predictable? Adv. Drug Delivery Rev. 60 2008 638 656
56. K. Roger, B. Cabane, and U. Olsson Emulsification through surfactant hydration: the PIC process revisited Langmuir 27 2011 604 611
57. L. Schiller, M. Emmett, C. Santa Ana, and J. Fordtran Osmotic effects of polyethylene glycol Gastroenterology 94 1988 933
58. J.C. Schwarz, V. Klang, S. Karall, D. Mahrhauser, G.P. Resch, and C. Valenta Optimisation of multiple W/O/W nanoemulsions for dermal delivery of aciclovir Int. J. Pharm. 435 2012 69 75
59. F. Shakeel, F.K. Alanazi, I.A. Alsarra, and N. Haq Solubilization behavior of paracetamol in transcutol-water mixtures at (298.15 to 333.15) K J. Chem. Eng. Data 58 2013 3551 3556
60. J. Siepmann, and N.A. Peppas Higuchi equation: derivation, applications, use and misuse Int. J. Pharm. 418 2011 6 12
61. R.G. Strickley Solubilizing excipients in oral and injectable formulations Pharm. Res. 21 2004 201 230
62. T. Tadros, P. Izquierdo, J. Esquena, and C. Solans Formation and stability of nano-emulsions Adv. Colloid Interface Sci. 108 2004 303 318
63. T.D. Thi, M. Van Speybroeck, V. Barillaro, J. Martens, P. Annaert, P. Augustijns, J. Van Humbeeck, J. Vermant, and G. Van den Mooter Formulate-ability of ten compounds with different physicochemical profiles in SMEDDS Eur. J. Pharm. Sci. 38 2009 479 488
64. V.P. Torchilin Structure and design of polymeric surfactant-based drug delivery systems J. Controlled Release 73 2001 137 172
65. G. Van den Mooter The use of amorphous solid dispersions: a formulation strategy to overcome poor solubility and dissolution rate Drug Discovery Today Technol. 9 2012 e79 e85
66. M. Vogt, K. Kunath, and J.B. Dressman Dissolution enhancement of fenofibrate by micronization, cogrinding and spray-drying: comparison with commercial preparations Eur. J. Pharm. Biopharm. 68 2008 283 288
67. L. Wang, J. Dong, J. Chen, J. Eastoe, and X. Li Design and optimization of a new self-nanoemulsifying drug delivery system J. Colloid Interface Sci. 330 2009 443 448
68. W. Xu, J. Riikonen, and V.P. Lehto Mesoporous systems for poorly soluble drugs Int. J. Pharm. 453 2013 181 197
69. X. Zhao, D. Chen, P. Gao, P. Ding, and K. Li Synthesis of ibuprofen eugenol ester and its microemulsion formulation for parenteral delivery Chem. Pharm. Bull. 53 2005 1246 1250