Investigation of surfactant/cosurfactant synergism impact on ibuprofen solubilization capacity and drug release characteristics of nonionic microemulsions

International Journal of Pharmaceutics

Volumn 433, Issue 1-2, 2012, Pages 25-33

  Djekic, Ljiljana ^a   Primorac, Marija ^a   Filipic, Slavica ^a   Agbaba, Danica ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Drug solubilization capacity; Ibuprofen; In vitro release testing (IVRT); Microemulsions; Surfactant cosurfactant synergism

Indexed keywords

COSURFACTANT; DEEP RELIEF; EXCIPIENT; HYDROGENATED CASTOR OIL; IBUPROFEN; LABRASOL; MYRISTIC ACID ISOPROPYL ESTER; SOLUBILISANT GAMMA 2421; SOLUBILISANT GAMMA 2429; SURFACTANT; UNCLASSIFIED DRUG;

ARTICLE; CONDUCTANCE; DRUG FORMULATION; DRUG POTENTIATION; DRUG RELEASE; DRUG RESEARCH; DRUG SCREENING; DRUG SOLUBILITY; DRUG SYNTHESIS; FLOW KINETICS; HYDROGEL; IN VITRO STUDY; MICROEMULSION; MICROSCOPY; PH; PRIORITY JOURNAL;

ADMINISTRATION, TOPICAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CASTOR OIL; DRUG SYNERGISM; EMULSIONS; EXCIPIENTS; HYDROGELS; HYDROGEN-ION CONCENTRATION; IBUPROFEN; KINETICS; MODELS, THEORETICAL; OCTOXYNOL; ORGANIC CHEMICALS; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYSORBATES; RHEOLOGY; SOLUBILITY; SURFACE-ACTIVE AGENTS; VISCOSITY;

EID: 84862848717     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.04.070     Document Type: Article

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