Influence of the introduction of a solubility enhancer on the formulation of lipidic nanoparticles with improved drug loading rates

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 75, Issue 2, 2010, Pages 117-127

  Malzert Freon A ^a   Saint Lorant, G ^a,b   Hennequin, D ^c   Gauduchon, P ^b   Poulain, L ^b   Rault, S ^a  

^a CENTRE D ETUDES ET DE RECHERCHE SUR LE MÉDICAMENT DE NORMANDIE   (France)

^b Biologie des Thérapies Innovantes des Cancers Localement Agressifs BioTICLA EA 4656   (France)

^c UNIVERSITÉ DE CAEN   (France)

Author keywords

Labrasol; Nanoparticles; Partial least square; Phase inversion; Tripentone

Indexed keywords

ANTINEOPLASTIC AGENT; GLYCEROL; LABRASOL; MIGLYOL; NANOCARRIER; SOLID LIPID NANOPARTICLE; TRIPENTONE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SOLUBILITY; ELECTRIC CONDUCTIVITY; ENCAPSULATION; FEASIBILITY STUDY; LIGHT SCATTERING; MICROEMULSION; MOLECULAR DYNAMICS; SOLVENT EFFECT; TEMPERATURE SENSITIVITY; TRANSMISSION ELECTRON MICROSCOPY;

ANTINEOPLASTIC AGENTS; DRUG STABILITY; EMULSIONS; EXCIPIENTS; LEAST-SQUARES ANALYSIS; LIPIDS; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; ORGANIC CHEMICALS; PARTICLE SIZE; PYRROLIZIDINE ALKALOIDS; SOLUBILITY; TEMPERATURE;

EID: 77952956199     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.02.003     Document Type: Article

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