Lipid based nanocarrier system for the potential oral delivery of decitabine: Formulation design, characterization, ex vivo, and in vivo assessment

International Journal of Pharmaceutics

Volumn 477, Issue 1-2, 2014, Pages 601-612

  Neupane, Yub Raj ^a   Srivastava, Manish ^a   Ahmad, Nafees ^a   Kumar, Neeraj ^b   Bhatnagar, Aseem ^b   Kohli, Kanchan ^a  

^a HAMDARD UNIVERSITY   (India)

^b INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

Author keywords

Atomic force microscopy; Decitabine; Lipid based nanocarrier; Oral drug delivery; Scintigraphy

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; NANOCARRIER; NANOSTRUCTURED LIPID CARRIER; TECHNETIUM 99M; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ATOMIC FORCE MICROSCOPY; CANCER CELL; CELL SURVIVAL; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG RELEASE; DRUG STABILITY; EHRLICH ASCITES TUMOR; EX VIVO STUDY; GAMMA SCINTIGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; MALE; NON SMALL CELL LUNG CANCER; NONHUMAN; PARTICLE SIZE; RAT; RESPONSE SURFACE METHOD; SUSTAINED DRUG RELEASE; THIN LAYER CHROMATOGRAPHY; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION; ZETA POTENTIAL;

EID: 84910012961     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.11.001     Document Type: Article

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