Accelerated ketoprofen release from polymeric matrices: Importance of the homogeneity/heterogeneity of excipient distribution

International Journal of Pharmaceutics

Volumn 457, Issue 1, 2013, Pages 298-307

  Gue, E ^a,b   Willart, J F ^a,c   Muschert, S ^a,b   Danede, F ^a,c   Delcourt, E ^b   Descamps, M ^a,c   Siepmann, J ^a,b  

^a UNIV LILLE   (France)

^b CHU de Lille   (France)

^c UNIVERSITÉ LILLE 1   (France)

Author keywords

Eudragit E; Hot melt extrusion; Ketoprofen; Poorly soluble drugs; Spray drying

Indexed keywords

EUDRAGIT; EXCIPIENT; KETOPROFEN;

ARTICLE; DISSOLUTION; DRUG DIFFUSION; DRUG RELEASE; KINETICS; MEASUREMENT; MICROSCOPY; PARTICLE SIZE; POLYMERIZATION; POWDER; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; X RAY DIFFRACTION;

HOT-MELT EXTRUSION; KETOPROFEN, EUDRAGIT(®) E; POORLY SOLUBLE DRUGS; SPRAY-DRYING;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DRUG COMPOUNDING; EXCIPIENTS; KETOPROFEN; POLYMERS; SOLUBILITY;

EID: 84888345196     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.09.023     Document Type: Article

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