The disordered hypervariable region and the folded catalytic domain of oncogenic K-Ras4B partner in phospholipid binding

Current Opinion in Structural Biology

Volumn 36, Issue , 2016, Pages 10-17

  Banerjee, Avik ^a   Jang, Hyunbum ^b   Nussinov, Ruth ^b,c   Gaponenko, Vadim ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CALMODULIN; GLYCINE; GUANOSINE TRIPHOSPHATE; K RAS PROTEIN; K RAS4B PROTEIN; ONCOPROTEIN; PHOSPHATIDIC ACID; PHOSPHOLIPID; UNCLASSIFIED DRUG; VALINE; ISOPROTEIN; K-RAS4B PROTEIN, HUMAN; PROTEIN BINDING; PROTEIN P21;

BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL MEMBRANE; ENZYME REGULATION; GENE MUTATION; HUMAN; MALIGNANT NEOPLASTIC DISEASE; MEMBRANE STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEFECT; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; REVIEW; ANIMAL; CHEMISTRY; ENZYME ACTIVE SITE; GENE EXPRESSION REGULATION; GENETIC VARIATION; GENETICS; METABOLISM; MUTATION; NEOPLASM; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALS; CATALYTIC DOMAIN; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VARIATION; HUMANS; MEMBRANE MICRODOMAINS; MUTATION; NEOPLASMS; PHOSPHOLIPIDS; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN ISOFORMS; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS P21(RAS); SIGNAL TRANSDUCTION;

EID: 84949981160     PISSN: 0959440X     EISSN: 1879033X     Source Type: Journal    
DOI: 10.1016/j.sbi.2015.11.010     Document Type: Review

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