Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 26, 2015, Pages 7996-8001

  Nan, Xiaolin ^a,b,c   Tamgüney, Tanja M ^d   Collisson, Eric A ^b,d   Lin, Li Jung ^c   Pitt, Cameron ^d   Galeas, Jacqueline ^d   Lewis, Sophia ^b   Gray, Joe W ^b,c,d   McCormick, Frank ^d   Chu, Steven ^e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c Oregon Health and Science University Department of Biomedical Engineering   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e STANFORD UNIVERSITY   (United States)

Author keywords

Cancer; MAPK signaling; Ras dimer; Single molecule imaging; Superresolution microscopy

Indexed keywords

GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; GUANOSINE TRIPHOSPHATE; RAS PROTEIN;

ARTICLE; CELL MEMBRANE; DIMERIZATION; FLUORESCENCE MICROSCOPY; HUMAN; MICROSCOPY; PHOTOACTIVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROCESSING; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CELL LINE; ENZYME ACTIVATION; HAMSTER; METABOLISM;

RATTUS;

ANIMALS; CELL LINE; CRICETINAE; DIMERIZATION; ENZYME ACTIVATION; GUANOSINE TRIPHOSPHATE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; RAS PROTEINS;

EID: 84937957816     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1509123112     Document Type: Article

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