Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression

Journal of Pathology

Volumn 187, Issue 4, 1999, Pages 433-438

  Al Mulla, Fahd ^a   Milner White, E James ^b   Going, James J ^c   Birnie, George D ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Oncogenic signal; Ras mutants; Ras structure; Signal transduction; Tumour aggression

Indexed keywords

ASPARTIC ACID; RAS PROTEIN; VALINE;

ARTICLE; BINDING AFFINITY; CANCER INVASION; CARCINOGENIC ACTIVITY; HUMAN; MALIGNANT NEOPLASTIC DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN STRUCTURE;

ASPARTIC ACID; CRYSTALLOGRAPHY; HUMANS; MUTATION; NEOPLASM INVASIVENESS; PHOSPHATES; PROTO-ONCOGENE PROTEINS P21(RAS); SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; VALINE;

EID: 0033052966     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199903)187:4<433::AID-PATH273>3.0.CO;2-E     Document Type: Article

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