-
1
-
-
84863980709
-
Genetic architectures of psychiatric disorders: the emerging picture and its implications
-
Sullivan P.F., Daly M.J., O'Donovan M. Genetic architectures of psychiatric disorders: the emerging picture and its implications. Nat Rev Genet 2012, 13:537-551.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 537-551
-
-
Sullivan, P.F.1
Daly, M.J.2
O'Donovan, M.3
-
2
-
-
67650732715
-
Advances in autism
-
Geschwind D.H. Advances in autism. Annu Rev Med 2009, 60:367-380.
-
(2009)
Annu Rev Med
, vol.60
, pp. 367-380
-
-
Geschwind, D.H.1
-
3
-
-
12344326514
-
Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs
-
Miyamoto S., Duncan G.E., Marx C.E., Lieberman J.A. Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs. Mol Psychiatry 2005, 10:79-104.
-
(2005)
Mol Psychiatry
, vol.10
, pp. 79-104
-
-
Miyamoto, S.1
Duncan, G.E.2
Marx, C.E.3
Lieberman, J.A.4
-
4
-
-
84870360228
-
Treatment-resistant depression: therapeutic trends, challenges, and future directions
-
Al-Harbi K.S. Treatment-resistant depression: therapeutic trends, challenges, and future directions. Patient Prefer Adherence 2012, 6:369-388.
-
(2012)
Patient Prefer Adherence
, vol.6
, pp. 369-388
-
-
Al-Harbi, K.S.1
-
5
-
-
77957273984
-
Animal models of neuropsychiatric disorders
-
Nestler E.J., Hyman S.E. Animal models of neuropsychiatric disorders. Nat Neurosci 2010, 13:1161-1169.
-
(2010)
Nat Neurosci
, vol.13
, pp. 1161-1169
-
-
Nestler, E.J.1
Hyman, S.E.2
-
6
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
7
-
-
84861441557
-
Application of reprogrammed patient cells to investigate the etiology of neurological and psychiatric disorders
-
Christian K., Song H., Ming G. Application of reprogrammed patient cells to investigate the etiology of neurological and psychiatric disorders. Frontiers Biol 2012, 7:179-188.
-
(2012)
Frontiers Biol
, vol.7
, pp. 179-188
-
-
Christian, K.1
Song, H.2
Ming, G.3
-
8
-
-
84901608878
-
Large-scale genomics unveils the genetic architecture of psychiatric disorders
-
Gratten J., Wray N.R., Keller M.C., Visscher P.M. Large-scale genomics unveils the genetic architecture of psychiatric disorders. Nat Neurosci 2014, 17:782-790.
-
(2014)
Nat Neurosci
, vol.17
, pp. 782-790
-
-
Gratten, J.1
Wray, N.R.2
Keller, M.C.3
Visscher, P.M.4
-
9
-
-
84904804929
-
Biological insights from 108 schizophrenia-associated genetic loci
-
Schizophrenia Working Group of the Psychiatric Genomics C. Biological insights from 108 schizophrenia-associated genetic loci. Nature 2014, 511:421-427.
-
(2014)
Nature
, vol.511
, pp. 421-427
-
-
-
10
-
-
68449086236
-
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
-
International Schizophrenia C., Purcell S.M., Wray N.R., Stone J.L., Visscher P.M., O'Donovan M.C., Sullivan P.F., Sklar P. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009, 460:748-752.
-
(2009)
Nature
, vol.460
, pp. 748-752
-
-
International Schizophrenia, C.1
Purcell, S.M.2
Wray, N.R.3
Stone, J.L.4
Visscher, P.M.5
O'Donovan, M.C.6
Sullivan, P.F.7
Sklar, P.8
-
11
-
-
84855954394
-
DISC1 at 10: connecting psychiatric genetics and neuroscience
-
Porteous D.J., Millar J.K., Brandon N.J., Sawa A. DISC1 at 10: connecting psychiatric genetics and neuroscience. Trends Mol Med 2011, 17:699-706.
-
(2011)
Trends Mol Med
, vol.17
, pp. 699-706
-
-
Porteous, D.J.1
Millar, J.K.2
Brandon, N.J.3
Sawa, A.4
-
12
-
-
23744517093
-
A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder
-
Sachs N.A., Sawa A., Holmes S.E., Ross C.A., DeLisi L.E., Margolis R.L. A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder. Mol Psychiatry 2005, 10:758-764.
-
(2005)
Mol Psychiatry
, vol.10
, pp. 758-764
-
-
Sachs, N.A.1
Sawa, A.2
Holmes, S.E.3
Ross, C.A.4
DeLisi, L.E.5
Margolis, R.L.6
-
13
-
-
84911360325
-
Synaptic dysregulation in a human iPS cell model of mental disorders
-
Wen Z., Nguyen H.N., Guo Z., Lalli M.A., Wang X., Su Y., Kim N.S., Yoon K.J., Shin J., Zhang C., et al. Synaptic dysregulation in a human iPS cell model of mental disorders. Nature 2014, 515:414-418.
-
(2014)
Nature
, vol.515
, pp. 414-418
-
-
Wen, Z.1
Nguyen, H.N.2
Guo, Z.3
Lalli, M.A.4
Wang, X.5
Su, Y.6
Kim, N.S.7
Yoon, K.J.8
Shin, J.9
Zhang, C.10
-
14
-
-
78549247463
-
L1 retrotransposition in neurons is modulated by MeCP2
-
Muotri A.R., Marchetto M.C., Coufal N.G., Oefner R., Yeo G., Nakashima K., Gage F.H. L1 retrotransposition in neurons is modulated by MeCP2. Nature 2010, 468:443-446.
-
(2010)
Nature
, vol.468
, pp. 443-446
-
-
Muotri, A.R.1
Marchetto, M.C.2
Coufal, N.G.3
Oefner, R.4
Yeo, G.5
Nakashima, K.6
Gage, F.H.7
-
15
-
-
78149488365
-
A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells
-
Marchetto M.C., Carromeu C., Acab A., Yu D., Yeo G.W., Mu Y., Chen G., Gage F.H., Muotri A.R. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell 2010, 143:527-539.
-
(2010)
Cell
, vol.143
, pp. 527-539
-
-
Marchetto, M.C.1
Carromeu, C.2
Acab, A.3
Yu, D.4
Yeo, G.W.5
Mu, Y.6
Chen, G.7
Gage, F.H.8
Muotri, A.R.9
-
16
-
-
79955602167
-
Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation
-
Cheung A.Y., Horvath L.M., Grafodatskaya D., Pasceri P., Weksberg R., Hotta A., Carrel L., Ellis J. Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation. Hum Mol Genet 2011, 20:2103-2115.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 2103-2115
-
-
Cheung, A.Y.1
Horvath, L.M.2
Grafodatskaya, D.3
Pasceri, P.4
Weksberg, R.5
Hotta, A.6
Carrel, L.7
Ellis, J.8
-
17
-
-
80053143413
-
Isogenic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease model
-
Ananiev G., Williams E.C., Li H., Chang Q. Isogenic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease model. PLoS One 2011, 6:e25255.
-
(2011)
PLoS One
, vol.6
, pp. e25255
-
-
Ananiev, G.1
Williams, E.C.2
Li, H.3
Chang, Q.4
-
18
-
-
84865773360
-
CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons
-
Ricciardi S., Ungaro F., Hambrock M., Rademacher N., Stefanelli G., Brambilla D., Sessa A., Magagnotti C., Bachi A., Giarda E., et al. CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons. Nat Cell Biol 2012, 14:911-923.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 911-923
-
-
Ricciardi, S.1
Ungaro, F.2
Hambrock, M.3
Rademacher, N.4
Stefanelli, G.5
Brambilla, D.6
Sessa, A.7
Magagnotti, C.8
Bachi, A.9
Giarda, E.10
-
19
-
-
84892789989
-
Increased l1 retrotransposition in the neuronal genome in schizophrenia
-
Bundo M., Toyoshima M., Okada Y., Akamatsu W., Ueda J., Nemoto-Miyauchi T., Sunaga F., Toritsuka M., Ikawa D., Kakita A., et al. Increased l1 retrotransposition in the neuronal genome in schizophrenia. Neuron 2014, 81:306-313.
-
(2014)
Neuron
, vol.81
, pp. 306-313
-
-
Bundo, M.1
Toyoshima, M.2
Okada, Y.3
Akamatsu, W.4
Ueda, J.5
Nemoto-Miyauchi, T.6
Sunaga, F.7
Toritsuka, M.8
Ikawa, D.9
Kakita, A.10
-
20
-
-
84946489377
-
Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons
-
Griesi-Oliveira K., Acab A., Gupta A.R., Sunaga D.Y., Chailangkarn T., Nicol X., Nunez Y., Walker M.F., Murdoch J.D., Sanders S.J., et al. Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Mol Psychiatry 2014, 20:1350-1365.
-
(2014)
Mol Psychiatry
, vol.20
, pp. 1350-1365
-
-
Griesi-Oliveira, K.1
Acab, A.2
Gupta, A.R.3
Sunaga, D.Y.4
Chailangkarn, T.5
Nicol, X.6
Nunez, Y.7
Walker, M.F.8
Murdoch, J.D.9
Sanders, S.J.10
-
21
-
-
5344223383
-
Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
-
Splawski I., Timothy K.W., Sharpe L.M., Decher N., Kumar P., Bloise R., Napolitano C., Schwartz P.J., Joseph R.M., Condouris K., et al. Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism. Cell 2004, 119:19-31.
-
(2004)
Cell
, vol.119
, pp. 19-31
-
-
Splawski, I.1
Timothy, K.W.2
Sharpe, L.M.3
Decher, N.4
Kumar, P.5
Bloise, R.6
Napolitano, C.7
Schwartz, P.J.8
Joseph, R.M.9
Condouris, K.10
-
22
-
-
84856088804
-
Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome
-
Pasca S.P., Portmann T., Voineagu I., Yazawa M., Shcheglovitov A., Pasca A.M., Cord B., Palmer T.D., Chikahisa S., Nishino S., et al. Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome. Nat Med 2011, 17:1657-1662.
-
(2011)
Nat Med
, vol.17
, pp. 1657-1662
-
-
Pasca, S.P.1
Portmann, T.2
Voineagu, I.3
Yazawa, M.4
Shcheglovitov, A.5
Pasca, A.M.6
Cord, B.7
Palmer, T.D.8
Chikahisa, S.9
Nishino, S.10
-
23
-
-
84927922272
-
Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome
-
Tian Y., Voineagu I., Pasca S.P., Won H., Chandran V., Horvath S., Dolmetsch R.E., Geschwind D.H. Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome. Genome Med 2014, 6:75.
-
(2014)
Genome Med
, vol.6
, pp. 75
-
-
Tian, Y.1
Voineagu, I.2
Pasca, S.P.3
Won, H.4
Chandran, V.5
Horvath, S.6
Dolmetsch, R.E.7
Geschwind, D.H.8
-
24
-
-
84858434210
-
CNVs: harbingers of a rare variant revolution in psychiatric genetics
-
Malhotra D., Sebat J. CNVs: harbingers of a rare variant revolution in psychiatric genetics. Cell 2012, 148:1223-1241.
-
(2012)
Cell
, vol.148
, pp. 1223-1241
-
-
Malhotra, D.1
Sebat, J.2
-
25
-
-
84922900619
-
The 15q11.2 BP1-BP2 microdeletion syndrome: a review
-
Cox D.M., Butler M.G. The 15q11.2 BP1-BP2 microdeletion syndrome: a review. Int J Mol Sci 2015, 16:4068-4082.
-
(2015)
Int J Mol Sci
, vol.16
, pp. 4068-4082
-
-
Cox, D.M.1
Butler, M.G.2
-
26
-
-
84904001347
-
Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity
-
Yoon K.J., Nguyen H.N., Ursini G., Zhang F., Kim N.S., Wen Z., Makri G., Nauen D., Shin J.H., Park Y., et al. Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity. Cell Stem Cell 2014, 15:79-91.
-
(2014)
Cell Stem Cell
, vol.15
, pp. 79-91
-
-
Yoon, K.J.1
Nguyen, H.N.2
Ursini, G.3
Zhang, F.4
Kim, N.S.5
Wen, Z.6
Makri, G.7
Nauen, D.8
Shin, J.H.9
Park, Y.10
-
27
-
-
84965113064
-
7q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages
-
Adamo A., Atashpaz S., Germain P.L., Zanella M., D'Agostino G., Albertin V., Chenoweth J., Micale L., Fusco C., Unger C., et al. 7q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages. Nat Genet 2015, 47:132-141.
-
(2015)
Nat Genet
, vol.47
, pp. 132-141
-
-
Adamo, A.1
Atashpaz, S.2
Germain, P.L.3
Zanella, M.4
D'Agostino, G.5
Albertin, V.6
Chenoweth, J.7
Micale, L.8
Fusco, C.9
Unger, C.10
-
28
-
-
77952738956
-
22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia
-
Karayiorgou M., Simon T.J., Gogos J.A. 22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia. Nat Rev Neurosci 2010, 11:402-416.
-
(2010)
Nat Rev Neurosci
, vol.11
, pp. 402-416
-
-
Karayiorgou, M.1
Simon, T.J.2
Gogos, J.A.3
-
29
-
-
84887627330
-
SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients
-
Shcheglovitov A., Shcheglovitova O., Yazawa M., Portmann T., Shu R., Sebastiano V., Krawisz A., Froehlich W., Bernstein J.A., Hallmayer J.F., et al. SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients. Nature 2013, 503:267-271.
-
(2013)
Nature
, vol.503
, pp. 267-271
-
-
Shcheglovitov, A.1
Shcheglovitova, O.2
Yazawa, M.3
Portmann, T.4
Shu, R.5
Sebastiano, V.6
Krawisz, A.7
Froehlich, W.8
Bernstein, J.A.9
Hallmayer, J.F.10
-
30
-
-
84862777863
-
Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs
-
Lee S.H., DeCandia T.R., Ripke S., Yang J., Schizophrenia Psychiatric Genome-Wide Association Study C, International Schizophrenia C, Molecular Genetics of Schizophrenia C, Sullivan P.F., Goddard M.E., Keller M.C., et al. Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs. Nat Genet 2012, 44:247-250.
-
(2012)
Nat Genet
, vol.44
, pp. 247-250
-
-
Lee, S.H.1
DeCandia, T.R.2
Ripke, S.3
Yang, J.4
Sullivan, P.F.5
Goddard, M.E.6
Keller, M.C.7
-
31
-
-
70349956425
-
A genome-wide linkage and association scan reveals novel loci for autism
-
Weiss L.A., Arking D.E., Gene Discovery Project of Johns H, the Autism C, Daly M.J., Chakravarti A. A genome-wide linkage and association scan reveals novel loci for autism. Nature 2009, 461:802-808.
-
(2009)
Nature
, vol.461
, pp. 802-808
-
-
Weiss, L.A.1
Arking, D.E.2
Johns, H.3
Autism, C.4
Daly, M.J.5
Chakravarti, A.6
-
33
-
-
84940978728
-
Human neuropsychiatric disease modeling using conditional deletion reveals synaptic transmission defects caused by heterozygous mutations in NRXN1
-
Pak C., Danko T., Zhang Y., Aoto J., Anderson G., Maxeiner S., Yi F., Wernig M., Sudhof T.C. Human neuropsychiatric disease modeling using conditional deletion reveals synaptic transmission defects caused by heterozygous mutations in NRXN1. Cell Stem Cell 2015, 17:316-328.
-
(2015)
Cell Stem Cell
, vol.17
, pp. 316-328
-
-
Pak, C.1
Danko, T.2
Zhang, Y.3
Aoto, J.4
Anderson, G.5
Maxeiner, S.6
Yi, F.7
Wernig, M.8
Sudhof, T.C.9
-
34
-
-
84941710463
-
Analysis of conditional heterozygous STXBP1 mutations in human neurons
-
Patzke C., Han Y., Covy J., Yi F., Maxeiner S., Wernig M., Sudhof T.C. Analysis of conditional heterozygous STXBP1 mutations in human neurons. J Clin Invest 2015, 125:3560-3571.
-
(2015)
J Clin Invest
, vol.125
, pp. 3560-3571
-
-
Patzke, C.1
Han, Y.2
Covy, J.3
Yi, F.4
Maxeiner, S.5
Wernig, M.6
Sudhof, T.C.7
-
35
-
-
84940787011
-
Genomic DISC1 disruption in hiPSCs alters Wnt signaling and neural cell fate
-
Srikanth P., Han K., Callahan D.G., Makovkina E., Muratore C.R., Lalli M.A., Zhou H., Boyd J.D., Kosik K.S., Selkoe D.J., et al. Genomic DISC1 disruption in hiPSCs alters Wnt signaling and neural cell fate. Cell Rep 2015, 12:1414-1429.
-
(2015)
Cell Rep
, vol.12
, pp. 1414-1429
-
-
Srikanth, P.1
Han, K.2
Callahan, D.G.3
Makovkina, E.4
Muratore, C.R.5
Lalli, M.A.6
Zhou, H.7
Boyd, J.D.8
Kosik, K.S.9
Selkoe, D.J.10
-
36
-
-
84868582029
-
Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient
-
Paulsen Bda S., de Moraes Maciel R., Galina A., Souza da Silveira M., dos Santos Souza C., Drummond H., Nascimento Pozzatto E., Silva H., Chicaybam L., Massuda R., et al. Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient. Cell Transplant 2012, 21:1547-1559.
-
(2012)
Cell Transplant
, vol.21
, pp. 1547-1559
-
-
Paulsen Bda, S.1
de Moraes Maciel, R.2
Galina, A.3
Souza da Silveira, M.4
dos Santos Souza, C.5
Drummond, H.6
Nascimento Pozzatto, E.7
Silva, H.8
Chicaybam, L.9
Massuda, R.10
-
37
-
-
84931268404
-
Genome engineering of isogenic human ES cells to model autism disorders
-
Martinez R.A., Stein J.L., Krostag A.R., Nelson A.M., Marken J.S., Menon V., May R.C., Yao Z., Kaykas A., Geschwind D.H., et al. Genome engineering of isogenic human ES cells to model autism disorders. Nucleic Acids Res 2015, 43:e65.
-
(2015)
Nucleic Acids Res
, vol.43
, pp. e65
-
-
Martinez, R.A.1
Stein, J.L.2
Krostag, A.R.3
Nelson, A.M.4
Marken, J.S.5
Menon, V.6
May, R.C.7
Yao, Z.8
Kaykas, A.9
Geschwind, D.H.10
-
38
-
-
79955884485
-
Modelling schizophrenia using human induced pluripotent stem cells
-
Brennand K.J., Simone A., Jou J., Gelboin-Burkhart C., Tran N., Sangar S., Li Y., Mu Y., Chen G., Yu D., et al. Modelling schizophrenia using human induced pluripotent stem cells. Nature 2011, 473:221-225.
-
(2011)
Nature
, vol.473
, pp. 221-225
-
-
Brennand, K.J.1
Simone, A.2
Jou, J.3
Gelboin-Burkhart, C.4
Tran, N.5
Sangar, S.6
Li, Y.7
Mu, Y.8
Chen, G.9
Yu, D.10
-
39
-
-
84884669370
-
Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients
-
Robicsek O., Karry R., Petit I., Salman-Kesner N., Muller F.J., Klein E., Aberdam D., Ben-Shachar D. Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients. Mol Psychiatry 2013, 18:1067-1076.
-
(2013)
Mol Psychiatry
, vol.18
, pp. 1067-1076
-
-
Robicsek, O.1
Karry, R.2
Petit, I.3
Salman-Kesner, N.4
Muller, F.J.5
Klein, E.6
Aberdam, D.7
Ben-Shachar, D.8
-
40
-
-
84899930065
-
Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders
-
Hashimoto-Torii K., Torii M., Fujimoto M., Nakai A., El Fatimy R., Mezger V., Ju M.J., Ishii S., Chao S.H., Brennand K.J., et al. Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders. Neuron 2014, 82:560-572.
-
(2014)
Neuron
, vol.82
, pp. 560-572
-
-
Hashimoto-Torii, K.1
Torii, M.2
Fujimoto, M.3
Nakai, A.4
El Fatimy, R.5
Mezger, V.6
Ju, M.J.7
Ishii, S.8
Chao, S.H.9
Brennand, K.J.10
-
41
-
-
84896083027
-
Modeling hippocampal neurogenesis using human pluripotent stem cells
-
Yu D.X., Di Giorgio F.P., Yao J., Marchetto M.C., Brennand K., Wright R., Mei A., McHenry L., Lisuk D., Grasmick J.M., et al. Modeling hippocampal neurogenesis using human pluripotent stem cells. Stem Cell Reports 2014, 2:295-310.
-
(2014)
Stem Cell Reports
, vol.2
, pp. 295-310
-
-
Yu, D.X.1
Di Giorgio, F.P.2
Yao, J.3
Marchetto, M.C.4
Brennand, K.5
Wright, R.6
Mei, A.7
McHenry, L.8
Lisuk, D.9
Grasmick, J.M.10
-
42
-
-
84929944337
-
Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities
-
Madison J.M., Zhou F., Nigam A., Hussain A., Barker D.D., Nehme R., van der Ven K., Hsu J., Wolf P., Fleishman M., et al. Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities. Mol Psychiatry 2015, 20:703-717.
-
(2015)
Mol Psychiatry
, vol.20
, pp. 703-717
-
-
Madison, J.M.1
Zhou, F.2
Nigam, A.3
Hussain, A.4
Barker, D.D.5
Nehme, R.6
van der Ven, K.7
Hsu, J.8
Wolf, P.9
Fleishman, M.10
-
43
-
-
84902508571
-
Transcripts involved in calcium signaling and telencephalic neuronal fate are altered in induced pluripotent stem cells from bipolar disorder patients
-
Chen H.M., DeLong C.J., Bame M., Rajapakse I., Herron T.J., McInnis M.G., O'Shea K.S. Transcripts involved in calcium signaling and telencephalic neuronal fate are altered in induced pluripotent stem cells from bipolar disorder patients. Transl Psychiatry 2014, 4:e375.
-
(2014)
Transl Psychiatry
, vol.4
, pp. e375
-
-
Chen, H.M.1
DeLong, C.J.2
Bame, M.3
Rajapakse, I.4
Herron, T.J.5
McInnis, M.G.6
O'Shea, K.S.7
-
44
-
-
84899506022
-
Genomic insights into the overlap between psychiatric disorders: implications for research and clinical practice
-
Doherty J.L., Owen M.J. Genomic insights into the overlap between psychiatric disorders: implications for research and clinical practice. Genome Med 2014, 6:29.
-
(2014)
Genome Med
, vol.6
, pp. 29
-
-
Doherty, J.L.1
Owen, M.J.2
-
45
-
-
84946239187
-
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
-
Mertens J., Wang Q.W., Kim Y., Yu D.X., Pham S., Yang B., Zheng Y., Diffenderfer K.E., Zhang J., Soltani S., et al. Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder. Nature 2015, 527:95-99.
-
(2015)
Nature
, vol.527
, pp. 95-99
-
-
Mertens, J.1
Wang, Q.W.2
Kim, Y.3
Yu, D.X.4
Pham, S.5
Yang, B.6
Zheng, Y.7
Diffenderfer, K.E.8
Zhang, J.9
Soltani, S.10
-
46
-
-
0023082787
-
Negative schizophrenic symptomatology and the PCP (phencyclidine) model of schizophrenia
-
Javitt D.C. Negative schizophrenic symptomatology and the PCP (phencyclidine) model of schizophrenia. Hillside J Clin Psychiatry 1987, 9:12-35.
-
(1987)
Hillside J Clin Psychiatry
, vol.9
, pp. 12-35
-
-
Javitt, D.C.1
-
47
-
-
77953188782
-
Glutamatergic theories of schizophrenia
-
Javitt D.C. Glutamatergic theories of schizophrenia. Isr J Psychiatry Relat Sci 2010, 47:4-16.
-
(2010)
Isr J Psychiatry Relat Sci
, vol.47
, pp. 4-16
-
-
Javitt, D.C.1
-
48
-
-
84873282055
-
Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo
-
Espuny-Camacho I., Michelsen K.A., Gall D., Linaro D., Hasche A., Bonnefont J., Bali C., Orduz D., Bilheu A., Herpoel A., et al. Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo. Neuron 2013, 77:440-456.
-
(2013)
Neuron
, vol.77
, pp. 440-456
-
-
Espuny-Camacho, I.1
Michelsen, K.A.2
Gall, D.3
Linaro, D.4
Hasche, A.5
Bonnefont, J.6
Bali, C.7
Orduz, D.8
Bilheu, A.9
Herpoel, A.10
-
49
-
-
70450159769
-
Coordination of sonic hedgehog and Wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells
-
Li X.J., Zhang X., Johnson M.A., Wang Z.B., Lavaute T., Zhang S.C. Coordination of sonic hedgehog and Wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells. Development 2009, 136:4055-4063.
-
(2009)
Development
, vol.136
, pp. 4055-4063
-
-
Li, X.J.1
Zhang, X.2
Johnson, M.A.3
Wang, Z.B.4
Lavaute, T.5
Zhang, S.C.6
-
50
-
-
84870030633
-
Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks
-
Shi Y., Kirwan P., Livesey F.J. Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks. Nat Protoc 2012, 7:1836-1846.
-
(2012)
Nat Protoc
, vol.7
, pp. 1836-1846
-
-
Shi, Y.1
Kirwan, P.2
Livesey, F.J.3
-
51
-
-
84862778046
-
Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses
-
S471
-
Shi Y., Kirwan P., Smith J., Robinson H.P., Livesey F.J. Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nat Neurosci 2012, 15:477-486. S471.
-
(2012)
Nat Neurosci
, vol.15
, pp. 477-486
-
-
Shi, Y.1
Kirwan, P.2
Smith, J.3
Robinson, H.P.4
Livesey, F.J.5
-
52
-
-
84865599035
-
GABA system dysfunction in autism and related disorders: from synapse to symptoms
-
Coghlan S., Horder J., Inkster B., Mendez M.A., Murphy D.G., Nutt D.J. GABA system dysfunction in autism and related disorders: from synapse to symptoms. Neurosci Biobehav Rev 2012, 36:2044-2055.
-
(2012)
Neurosci Biobehav Rev
, vol.36
, pp. 2044-2055
-
-
Coghlan, S.1
Horder, J.2
Inkster, B.3
Mendez, M.A.4
Murphy, D.G.5
Nutt, D.J.6
-
54
-
-
84856046439
-
Interneuron dysfunction in psychiatric disorders
-
Marin O. Interneuron dysfunction in psychiatric disorders. Nat Rev Neurosci 2012, 13:107-120.
-
(2012)
Nat Rev Neurosci
, vol.13
, pp. 107-120
-
-
Marin, O.1
-
55
-
-
80052672692
-
Alterations of GABAergic signaling in autism spectrum disorders
-
Pizzarelli R., Cherubini E. Alterations of GABAergic signaling in autism spectrum disorders. Neural Plast 2011, 2011:297153.
-
(2011)
Neural Plast
, vol.2011
, pp. 297153
-
-
Pizzarelli, R.1
Cherubini, E.2
-
56
-
-
78149431869
-
Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes
-
Chao H.T., Chen H., Samaco R.C., Xue M., Chahrour M., Yoo J., Neul J.L., Gong S., Lu H.C., Heintz N., et al. Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature 2010, 468:263-269.
-
(2010)
Nature
, vol.468
, pp. 263-269
-
-
Chao, H.T.1
Chen, H.2
Samaco, R.C.3
Xue, M.4
Chahrour, M.5
Yoo, J.6
Neul, J.L.7
Gong, S.8
Lu, H.C.9
Heintz, N.10
-
57
-
-
84883387241
-
Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells
-
Liu Y., Liu H., Sauvey C., Yao L., Zarnowska E.D., Zhang S.C. Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells. Nat Protoc 2013, 8:1670-1679.
-
(2013)
Nat Protoc
, vol.8
, pp. 1670-1679
-
-
Liu, Y.1
Liu, H.2
Sauvey, C.3
Yao, L.4
Zarnowska, E.D.5
Zhang, S.C.6
-
58
-
-
84877342649
-
Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits
-
Liu Y., Weick J.P., Liu H., Krencik R., Zhang X., Ma L., Zhou G.M., Ayala M., Zhang S.C. Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits. Nat Biotechnol 2013, 31:440-447.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 440-447
-
-
Liu, Y.1
Weick, J.P.2
Liu, H.3
Krencik, R.4
Zhang, X.5
Ma, L.6
Zhou, G.M.7
Ayala, M.8
Zhang, S.C.9
-
59
-
-
84877271854
-
Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells
-
Maroof A.M., Keros S., Tyson J.A., Ying S.W., Ganat Y.M., Merkle F.T., Liu B., Goulburn A., Stanley E.G., Elefanty A.G., et al. Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell Stem Cell 2013, 12:559-572.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 559-572
-
-
Maroof, A.M.1
Keros, S.2
Tyson, J.A.3
Ying, S.W.4
Ganat, Y.M.5
Merkle, F.T.6
Liu, B.7
Goulburn, A.8
Stanley, E.G.9
Elefanty, A.G.10
-
60
-
-
84877301288
-
Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development
-
Nicholas C.R., Chen J., Tang Y., Southwell D.G., Chalmers N., Vogt D., Arnold C.M., Chen Y.J., Stanley E.G., Elefanty A.G., et al. Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development. Cell Stem Cell 2013, 12:573-586.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 573-586
-
-
Nicholas, C.R.1
Chen, J.2
Tang, Y.3
Southwell, D.G.4
Chalmers, N.5
Vogt, D.6
Arnold, C.M.7
Chen, Y.J.8
Stanley, E.G.9
Elefanty, A.G.10
-
61
-
-
84881259785
-
The dynamics of autism spectrum disorders: how neurotoxic compounds and neurotransmitters interact
-
Quaak I., Brouns M.R., Van de Bor M. The dynamics of autism spectrum disorders: how neurotoxic compounds and neurotransmitters interact. Int J Environ Res Public Health 2013, 10:3384-3408.
-
(2013)
Int J Environ Res Public Health
, vol.10
, pp. 3384-3408
-
-
Quaak, I.1
Brouns, M.R.2
Van de Bor, M.3
-
62
-
-
84916630503
-
Reward processing dysfunction in major depression, bipolar disorder and schizophrenia
-
Whitton A.E., Treadway M.T., Pizzagalli D.A. Reward processing dysfunction in major depression, bipolar disorder and schizophrenia. Curr Opin Psychiatry 2015, 28:7-12.
-
(2015)
Curr Opin Psychiatry
, vol.28
, pp. 7-12
-
-
Whitton, A.E.1
Treadway, M.T.2
Pizzagalli, D.A.3
-
63
-
-
84926415997
-
Schizophrenia: overview and dopamine dysfunction
-
Abi-Dargham A. Schizophrenia: overview and dopamine dysfunction. J Clin Psychiatry 2014, 75:e31.
-
(2014)
J Clin Psychiatry
, vol.75
, pp. e31
-
-
Abi-Dargham, A.1
-
64
-
-
0026070134
-
Dopamine in schizophrenia: a review and reconceptualization
-
Davis K.L., Kahn R.S., Ko G., Davidson M. Dopamine in schizophrenia: a review and reconceptualization. Am J Psychiatry 1991, 148:1474-1486.
-
(1991)
Am J Psychiatry
, vol.148
, pp. 1474-1486
-
-
Davis, K.L.1
Kahn, R.S.2
Ko, G.3
Davidson, M.4
-
65
-
-
0023215296
-
Implications of normal brain development for the pathogenesis of schizophrenia
-
Weinberger D.R. Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry 1987, 44:660-669.
-
(1987)
Arch Gen Psychiatry
, vol.44
, pp. 660-669
-
-
Weinberger, D.R.1
-
66
-
-
62149125434
-
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
-
Chambers S.M., Fasano C.A., Papapetrou E.P., Tomishima M., Sadelain M., Studer L. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotechnol 2009, 27:275-280.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 275-280
-
-
Chambers, S.M.1
Fasano, C.A.2
Papapetrou, E.P.3
Tomishima, M.4
Sadelain, M.5
Studer, L.6
-
67
-
-
84355166561
-
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease
-
Kriks S., Shim J.W., Piao J., Ganat Y.M., Wakeman D.R., Xie Z., Carrillo-Reid L., Auyeung G., Antonacci C., Buch A., et al. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 2011, 480:547-551.
-
(2011)
Nature
, vol.480
, pp. 547-551
-
-
Kriks, S.1
Shim, J.W.2
Piao, J.3
Ganat, Y.M.4
Wakeman, D.R.5
Xie, Z.6
Carrillo-Reid, L.7
Auyeung, G.8
Antonacci, C.9
Buch, A.10
-
68
-
-
78149302874
-
Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions
-
Swistowski A., Peng J., Liu Q., Mali P., Rao M.S., Cheng L., Zeng X. Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. Stem Cells 2010, 28:1893-1904.
-
(2010)
Stem Cells
, vol.28
, pp. 1893-1904
-
-
Swistowski, A.1
Peng, J.2
Liu, Q.3
Mali, P.4
Rao, M.S.5
Cheng, L.6
Zeng, X.7
-
69
-
-
80054757204
-
Directed differentiation of dopamine neurons from human pluripotent stem cells
-
Ma L., Liu Y., Zhang S.C. Directed differentiation of dopamine neurons from human pluripotent stem cells. Methods Mol Biol 2011, 767:411-418.
-
(2011)
Methods Mol Biol
, vol.767
, pp. 411-418
-
-
Ma, L.1
Liu, Y.2
Zhang, S.C.3
-
70
-
-
84861203696
-
Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells
-
Juopperi T.A., Kim W.R., Chiang C.H., Yu H., Margolis R.L., Ross C.A., Ming G.L., Song H. Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells. Mol Brain 2012, 5:17.
-
(2012)
Mol Brain
, vol.5
, pp. 17
-
-
Juopperi, T.A.1
Kim, W.R.2
Chiang, C.H.3
Yu, H.4
Margolis, R.L.5
Ross, C.A.6
Ming, G.L.7
Song, H.8
-
71
-
-
56549115885
-
Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells
-
Marchetto M.C., Muotri A.R., Mu Y., Smith A.M., Cezar G.G., Gage F.H. Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells. Cell Stem Cell 2008, 3:649-657.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 649-657
-
-
Marchetto, M.C.1
Muotri, A.R.2
Mu, Y.3
Smith, A.M.4
Cezar, G.G.5
Gage, F.H.6
-
72
-
-
80054798510
-
Directed differentiation of functional astroglial subtypes from human pluripotent stem cells
-
Krencik R., Zhang S.C. Directed differentiation of functional astroglial subtypes from human pluripotent stem cells. Nat Protoc 2011, 6:1710-1717.
-
(2011)
Nat Protoc
, vol.6
, pp. 1710-1717
-
-
Krencik, R.1
Zhang, S.C.2
-
73
-
-
82255175070
-
Specification of neuronal and glial subtypes from human pluripotent stem cells
-
Liu H., Zhang S.C. Specification of neuronal and glial subtypes from human pluripotent stem cells. Cell Mol Life Sci 2011, 68:3995-4008.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 3995-4008
-
-
Liu, H.1
Zhang, S.C.2
-
74
-
-
84943581853
-
Pluripotent stem cell-derived radial glia-like cells as stable intermediate for efficient generation of human oligodendrocytes
-
Gorris R., Fischer J., Erwes K.L., Kesavan J., Peterson D.A., Alexander M., Nothen M.M., Peitz M., Quandel T., Karus M., et al. Pluripotent stem cell-derived radial glia-like cells as stable intermediate for efficient generation of human oligodendrocytes. Glia 2015, 63:2152-2167.
-
(2015)
Glia
, vol.63
, pp. 2152-2167
-
-
Gorris, R.1
Fischer, J.2
Erwes, K.L.3
Kesavan, J.4
Peterson, D.A.5
Alexander, M.6
Nothen, M.M.7
Peitz, M.8
Quandel, T.9
Karus, M.10
-
75
-
-
73949130191
-
Differentiation of human oligodendrocytes from pluripotent stem cells
-
Hu B.Y., Du Z.W., Zhang S.C. Differentiation of human oligodendrocytes from pluripotent stem cells. Nat Protoc 2009, 4:1614-1622.
-
(2009)
Nat Protoc
, vol.4
, pp. 1614-1622
-
-
Hu, B.Y.1
Du, Z.W.2
Zhang, S.C.3
-
76
-
-
84861585681
-
Insights into cortical oscillations arising from optogenetic studies
-
Sohal V.S. Insights into cortical oscillations arising from optogenetic studies. Biol Psychiatry 2012, 71:1039-1045.
-
(2012)
Biol Psychiatry
, vol.71
, pp. 1039-1045
-
-
Sohal, V.S.1
-
77
-
-
84929697246
-
Alterations in cortical network oscillations and parvalbumin neurons in schizophrenia
-
Gonzalez-Burgos G., Cho R.Y., Lewis D.A. Alterations in cortical network oscillations and parvalbumin neurons in schizophrenia. Biol Psychiatry 2015, 77:1031-1040.
-
(2015)
Biol Psychiatry
, vol.77
, pp. 1031-1040
-
-
Gonzalez-Burgos, G.1
Cho, R.Y.2
Lewis, D.A.3
-
78
-
-
84864880991
-
Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
-
Ramskold D., Luo S., Wang Y.C., Li R., Deng Q., Faridani O.R., Daniels G.A., Khrebtukova I., Loring J.F., Laurent L.C., et al. Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells. Nat Biotechnol 2012, 30:777-782.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 777-782
-
-
Ramskold, D.1
Luo, S.2
Wang, Y.C.3
Li, R.4
Deng, Q.5
Faridani, O.R.6
Daniels, G.A.7
Khrebtukova, I.8
Loring, J.F.9
Laurent, L.C.10
-
79
-
-
79955666627
-
Modeling neurological diseases using patient-derived induced pluripotent stem cells
-
Juopperi T.A., Song H., Ming G.L. Modeling neurological diseases using patient-derived induced pluripotent stem cells. Future Neurol 2011, 6:363-373.
-
(2011)
Future Neurol
, vol.6
, pp. 363-373
-
-
Juopperi, T.A.1
Song, H.2
Ming, G.L.3
-
80
-
-
84904396621
-
Organogenesis in a dish: modeling development and disease using organoid technologies
-
Lancaster M.A., Knoblich J.A. Organogenesis in a dish: modeling development and disease using organoid technologies. Science 2014, 345:1247125.
-
(2014)
Science
, vol.345
, pp. 1247125
-
-
Lancaster, M.A.1
Knoblich, J.A.2
-
81
-
-
84878760040
-
Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications
-
Sato T., Clevers H. Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science 2013, 340:1190-1194.
-
(2013)
Science
, vol.340
, pp. 1190-1194
-
-
Sato, T.1
Clevers, H.2
-
82
-
-
84877275352
-
Next-generation regenerative medicine: organogenesis from stem cells in 3D culture
-
Sasai Y. Next-generation regenerative medicine: organogenesis from stem cells in 3D culture. Cell Stem Cell 2013, 12:520-530.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 520-530
-
-
Sasai, Y.1
-
83
-
-
79959924122
-
Development and evolution of the human neocortex
-
Lui J.H., Hansen D.V., Kriegstein A.R. Development and evolution of the human neocortex. Cell 2011, 146:18-36.
-
(2011)
Cell
, vol.146
, pp. 18-36
-
-
Lui, J.H.1
Hansen, D.V.2
Kriegstein, A.R.3
-
84
-
-
84890282623
-
Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex
-
Kadoshima T., Sakaguchi H., Nakano T., Soen M., Ando S., Eiraku M., Sasai Y. Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex. Proc Natl Acad Sci U S A 2013, 110:20284-20289.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 20284-20289
-
-
Kadoshima, T.1
Sakaguchi, H.2
Nakano, T.3
Soen, M.4
Ando, S.5
Eiraku, M.6
Sasai, Y.7
-
85
-
-
84937212591
-
FOXG1-dependent dysregulation of GABA/glutamate neuron differentiation in Autism Spectrum Disorders
-
Mariani J., Coppola G., Zhang P., Abyzov A., Provini L., Tomasini L., Amenduni M., Szekely A., Palejev D., Wilson M., et al. FOXG1-dependent dysregulation of GABA/glutamate neuron differentiation in Autism Spectrum Disorders. Cell 2015, 162:375-390.
-
(2015)
Cell
, vol.162
, pp. 375-390
-
-
Mariani, J.1
Coppola, G.2
Zhang, P.3
Abyzov, A.4
Provini, L.5
Tomasini, L.6
Amenduni, M.7
Szekely, A.8
Palejev, D.9
Wilson, M.10
-
86
-
-
84934442315
-
Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
-
Pasca A.M., Sloan S.A., Clarke L.E., Tian Y., Makinson C.D., Huber N., Kim C.H., Park J.Y., O'Rourke N.A., Nguyen K.D., et al. Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture. Nat Methods 2015, 12:671-678.
-
(2015)
Nat Methods
, vol.12
, pp. 671-678
-
-
Pasca, A.M.1
Sloan, S.A.2
Clarke, L.E.3
Tian, Y.4
Makinson, C.D.5
Huber, N.6
Kim, C.H.7
Park, J.Y.8
O'Rourke, N.A.9
Nguyen, K.D.10
-
87
-
-
84884414984
-
Cerebral organoids model human brain development and microcephaly
-
Lancaster M.A., Renner M., Martin C.A., Wenzel D., Bicknell L.S., Hurles M.E., Homfray T., Penninger J.M., Jackson A.P., Knoblich J.A. Cerebral organoids model human brain development and microcephaly. Nature 2013, 501:373-379.
-
(2013)
Nature
, vol.501
, pp. 373-379
-
-
Lancaster, M.A.1
Renner, M.2
Martin, C.A.3
Wenzel, D.4
Bicknell, L.S.5
Hurles, M.E.6
Homfray, T.7
Penninger, J.M.8
Jackson, A.P.9
Knoblich, J.A.10
-
88
-
-
70349301819
-
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
-
Lee G., Papapetrou E.P., Kim H., Chambers S.M., Tomishima M.J., Fasano C.A., Ganat Y.M., Menon J., Shimizu F., Viale A., et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 2009, 461:402-406.
-
(2009)
Nature
, vol.461
, pp. 402-406
-
-
Lee, G.1
Papapetrou, E.P.2
Kim, H.3
Chambers, S.M.4
Tomishima, M.J.5
Fasano, C.A.6
Ganat, Y.M.7
Menon, J.8
Shimizu, F.9
Viale, A.10
-
89
-
-
84866398196
-
A high-throughput screen for Wnt/beta-catenin signaling pathway modulators in human iPSC-derived neural progenitors
-
Zhao W.N., Cheng C., Theriault K.M., Sheridan S.D., Tsai L.H., Haggarty S.J. A high-throughput screen for Wnt/beta-catenin signaling pathway modulators in human iPSC-derived neural progenitors. J Biomol Screen 2012, 17:1252-1263.
-
(2012)
J Biomol Screen
, vol.17
, pp. 1252-1263
-
-
Zhao, W.N.1
Cheng, C.2
Theriault, K.M.3
Sheridan, S.D.4
Tsai, L.H.5
Haggarty, S.J.6
-
90
-
-
84863376218
-
Versatile pathway-centric approach based on high-throughput sequencing to anticancer drug discovery
-
Li H., Zhou H., Wang D., Qiu J., Zhou Y., Li X., Rosenfeld M.G., Ding S., Fu X.D. Versatile pathway-centric approach based on high-throughput sequencing to anticancer drug discovery. Proc Natl Acad Sci U S A 2012, 109:4609-4614.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 4609-4614
-
-
Li, H.1
Zhou, H.2
Wang, D.3
Qiu, J.4
Zhou, Y.5
Li, X.6
Rosenfeld, M.G.7
Ding, S.8
Fu, X.D.9
-
91
-
-
84924721164
-
Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia
-
Brennand K., Savas J.N., Kim Y., Tran N., Simone A., Hashimoto-Torii K., Beaumont K.G., Kim H.J., Topol A., Ladran I., et al. Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia. Mol Psychiatry 2015, 20:361-368.
-
(2015)
Mol Psychiatry
, vol.20
, pp. 361-368
-
-
Brennand, K.1
Savas, J.N.2
Kim, Y.3
Tran, N.4
Simone, A.5
Hashimoto-Torii, K.6
Beaumont, K.G.7
Kim, H.J.8
Topol, A.9
Ladran, I.10
-
92
-
-
84929128315
-
Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder
-
Bavamian S., Mellios N., Lalonde J., Fass D.M., Wang J., Sheridan S.D., Madison J.M., Zhou F., Rueckert E.H., Barker D., et al. Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder. Mol Psychiatry 2015.
-
(2015)
Mol Psychiatry
-
-
Bavamian, S.1
Mellios, N.2
Lalonde, J.3
Fass, D.M.4
Wang, J.5
Sheridan, S.D.6
Madison, J.M.7
Zhou, F.8
Rueckert, E.H.9
Barker, D.10
|