MicroRNA-21 deficiency protects from lupus-like autoimmunity in the chronic graft-versus-host disease model of systemic lupus erythematosus

Clinical Immunology

Volumn 162, Issue , 2016, Pages 100-106

  Garchow, Barry ^a   Kiriakidou, Marianthi ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Autoantibodies; Autoimmunity; B cells; CGVHD; Co stimulatory pathways; Cytokines; IL 17; Lupus; Lupus nephritis; MicroRNA; MiR 21; SLE; Splenomegaly; T cells; Th17; Tregs

Indexed keywords

AUTOANTIBODY; DOUBLE STRANDED DNA; INTERLEUKIN 17; MICRORNA 21; TRANSCRIPTION FACTOR FOXP3; MICRORNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE ACTIVATION; CD4+ CD25+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL EXPANSION; CELL INTERACTION; CELL POPULATION; CHRONIC GRAFT VERSUS HOST DISEASE; CONTROLLED STUDY; FEMALE; LUPUS LIKE SYNDROME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN URINE LEVEL; PROTEINURIA; REGULATORY T LYMPHOCYTE; SPLENOMEGALY; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE ACTIVATION; TH17 CELL; ANIMAL; COMPLICATION; DISEASE MODEL; FLOW CYTOMETRY; GENETICS; GRAFT VERSUS HOST REACTION; HUMAN; IMMUNOLOGY;

ANIMALS; AUTOIMMUNITY; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; GRAFT VS HOST DISEASE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; MICRORNAS;

EID: 84949294289     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2015.11.010     Document Type: Article

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