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Volumn 5, Issue 2, 2014, Pages

MicroRNA-21 regulates T-cell apoptosis by directly targeting the tumor suppressor gene Tipe2

Author keywords

apoptosis; MiR 21; NF B; Tipe2; TNFAIP8

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA 21; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA INDUCED PROTEIN 8 LIKE 2; UNCLASSIFIED DRUG;

EID: 84896757119     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.47     Document Type: Article
Times cited : (79)

References (59)
  • 2
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6: 857-866.
    • (2006) Nat Rev Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 3
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • He L, Hannon GJ. MicroRNAs: Small RNAs with a big role in gene regulation. Nat Rev Genet 2004; 5: 522-531.
    • (2004) Nat Rev Genet , vol.5 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 5
    • 40449098091 scopus 로고    scopus 로고
    • MicroRNAs and immunity: Novel players in the regulation of normal immune function and inflammation
    • Sonkoly E, Stahle M, Pivarcsi A. MicroRNAs and immunity: Novel players in the regulation of normal immune function and inflammation. Semin Cancer Biol 2008; 18: 131-140.
    • (2008) Semin Cancer Biol , vol.18 , pp. 131-140
    • Sonkoly, E.1    Stahle, M.2    Pivarcsi, A.3
  • 6
    • 58149085504 scopus 로고    scopus 로고
    • MicroRNA control in the immune system: Basic principles
    • Xiao C, Rajewsky K. MicroRNA control in the immune system: Basic principles. Cell 2009; 136: 26-36.
    • (2009) Cell , vol.136 , pp. 26-36
    • Xiao, C.1    Rajewsky, K.2
  • 7
    • 84856758666 scopus 로고    scopus 로고
    • MicroRNAs in acute leukemia: From biological players to clinical contributors
    • Schotte D, Pieters R, Den Boer ML. MicroRNAs in acute leukemia: From biological players to clinical contributors. Leukemia 2012; 26: 1-12.
    • (2012) Leukemia , vol.26 , pp. 1-12
    • Schotte, D.1    Pieters, R.2    Den Boer, M.L.3
  • 8
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. MicroRNAs: Target recognition and regulatory functions. Cell 2009; 136: 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 10
    • 69249099366 scopus 로고    scopus 로고
    • Helicobacter pylori and gastric cancer: Possible role of microRNAs in this intimate relationship
    • Belair C, Darfeuille F, Staedel C. Helicobacter pylori and gastric cancer: Possible role of microRNAs in this intimate relationship. Clin Microbiol Infect 2009; 15: 806-812.
    • (2009) Clin Microbiol Infect , vol.15 , pp. 806-812
    • Belair, C.1    Darfeuille, F.2    Staedel, C.3
  • 11
    • 36649025655 scopus 로고    scopus 로고
    • OncomiRs: The discovery and progress of microRNAs in cancers
    • Cho WC. OncomiRs: The discovery and progress of microRNAs in cancers. Mol Cancer 2007; 6: 60.
    • (2007) Mol Cancer , vol.6 , pp. 60
    • Cho, W.C.1
  • 14
    • 58649107855 scopus 로고    scopus 로고
    • MicroRNA and cancer-focus on apoptosis
    • Wang Y, Lee CG. MicroRNA and cancer-focus on apoptosis. J Cell Mol Med 2009; 13: 12-23.
    • (2009) J Cell Mol Med , vol.13 , pp. 12-23
    • Wang, Y.1    Lee, C.G.2
  • 15
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 2005; 65: 6029-6033.
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 18
  • 19
    • 78049450833 scopus 로고    scopus 로고
    • The magic and mystery of miR-21
    • Morrisey EE. The magic and mystery of miR-21. J Clin Invest 2010; 120: 3817-3819.
    • (2010) J Clin Invest , vol.120 , pp. 3817-3819
    • Morrisey, E.E.1
  • 22
    • 55249119513 scopus 로고    scopus 로고
    • MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha
    • Wu F, Zikusoka M, Trindade A, Dassopoulos T, Harris ML, Bayless TM et al. MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha. Gastroenterology 2008; 135: 1624-1635.
    • (2008) Gastroenterology , vol.135 , pp. 1624-1635
    • Wu, F.1    Zikusoka, M.2    Trindade, A.3    Dassopoulos, T.4    Harris, M.L.5    Bayless, T.M.6
  • 24
    • 75949106927 scopus 로고    scopus 로고
    • Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status
    • Zhou X, Ren Y, Moore L, Mei M, You Y, Xu P et al. Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status. Lab Invest 2010; 90: 144-155.
    • (2010) Lab Invest , vol.90 , pp. 144-155
    • Zhou, X.1    Ren, Y.2    Moore, L.3    Mei, M.4    You, Y.5    Xu, P.6
  • 25
    • 80053074068 scopus 로고    scopus 로고
    • MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-Type hypersensitivity
    • Lu TX, Hartner J, Lim EJ, Fabry V, Mingler MK, Cole ET et al. MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-Type hypersensitivity. J Immunol 2011; 187: 3362-3373.
    • (2011) J Immunol , vol.187 , pp. 3362-3373
    • Lu, T.X.1    Hartner, J.2    Lim, E.J.3    Fabry, V.4    Mingler, M.K.5    Cole, E.T.6
  • 26
    • 84858397752 scopus 로고    scopus 로고
    • MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis
    • Meisgen F, Xu N, Wei T, Janson PC, Obad S, Broom O et al. MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis. Exp Dermatol 2012; 21: 312-314.
    • (2012) Exp Dermatol , vol.21 , pp. 312-314
    • Meisgen, F.1    Xu, N.2    Wei, T.3    Janson, P.C.4    Obad, S.5    Broom, O.6
  • 27
    • 84855353486 scopus 로고    scopus 로고
    • MiR-21 functionally interacts with the 3'UTR of chemokine CCL20 and down-regulates CCL20 expression in miR-21 transfected colorectal cancer cells
    • Vicinus B, Rubie C, Faust SK, Frick VO, Ghadjar P, Wagner M et al. miR-21 functionally interacts with the 3'UTR of chemokine CCL20 and down-regulates CCL20 expression in miR-21 transfected colorectal cancer cells. Cancer Lett 2012; 316: 105-112.
    • (2012) Cancer Lett , vol.316 , pp. 105-112
    • Vicinus, B.1    Rubie, C.2    Faust, S.K.3    Frick, V.O.4    Ghadjar, P.5    Wagner, M.6
  • 28
    • 79951516643 scopus 로고    scopus 로고
    • MicroRNA-21 expression in CD4+ T cells is regulated by STAT3 and is pathologically involved in Sezary syndrome
    • van der Fits L, van Kester MS, Qin Y, Out-Luiting JJ, Smit F, Zoutman WH et al. MicroRNA-21 expression in CD4+ T cells is regulated by STAT3 and is pathologically involved in Sezary syndrome. J Invest Dermatol 2011; 131: 762-768.
    • (2011) J Invest Dermatol , vol.131 , pp. 762-768
    • Van Der Fits, L.1    Van Kester, M.S.2    Qin, Y.3    Out-Luiting, J.J.4    Smit, F.5    Zoutman, W.H.6
  • 30
    • 0033007321 scopus 로고    scopus 로고
    • Mature T lymphocyte apoptosis-immune regulation in a dynamic and unpredictable antigenic environment
    • Lenardo M, Chan KM, Hornung F, McFarland H, Siegel R, Wang J et al. Mature T lymphocyte apoptosis-immune regulation in a dynamic and unpredictable antigenic environment. Annu Rev Immunol 1999; 17: 221-253.
    • (1999) Annu Rev Immunol , vol.17 , pp. 221-253
    • Lenardo, M.1    Chan, K.M.2    Hornung, F.3    McFarland, H.4    Siegel, R.5    Wang, J.6
  • 31
    • 0026458406 scopus 로고
    • TNF activates nfkappa b by phosphatidylcholine-specific phospholipase c-induced acidic" sphingomyelin breakdown
    • Schü tze S, Potthoff K, Machleidt T, Berkovic D, Wiegmann K, Krönke M. TNF activates NFkappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. Cell 1992; 71: 765-776.
    • (1992) Cell , vol.71 , pp. 765-776
    • Schütze, S.1    Potthoff, K.2    Machleidt, T.3    Berkovic, D.4    Wiegmann, K.5    Krönke, M.6
  • 32
    • 0033596127 scopus 로고    scopus 로고
    • Control of apoptosis by Rel/NF-kappaB transcription factors
    • Barkett M, Gilmore TD. Control of apoptosis by Rel/NF-kappaB transcription factors. Oncogene 1999; 18: 6910-6924.
    • (1999) Oncogene , vol.18 , pp. 6910-6924
    • Barkett, M.1    Gilmore, T.D.2
  • 33
    • 0344406188 scopus 로고    scopus 로고
    • Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo function
    • Zheng Y, Vig M, Lyons J, Van Parijs L, Beg AA. Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo function. J Exp Med 2003; 197: 861-874.
    • (2003) J Exp Med , vol.197 , pp. 861-874
    • Zheng, Y.1    Vig, M.2    Lyons, J.3    Van Parijs, L.4    Beg, A.A.5
  • 34
    • 77955511571 scopus 로고    scopus 로고
    • Tissue-specific expression of TIPE2 provides insights into its function
    • Zhang G, Hao C, Lou Y, Xi W, Wang X, Wang Y et al. Tissue-specific expression of TIPE2 provides insights into its function. Mol Immunol 2010; 47: 2435-2442.
    • (2010) Mol Immunol , vol.47 , pp. 2435-2442
    • Zhang, G.1    Hao, C.2    Lou, Y.3    Xi, W.4    Wang, X.5    Wang, Y.6
  • 35
    • 79954601991 scopus 로고    scopus 로고
    • The unique expression profile of human TIPE2 suggests new functions beyond its role in immune regulation
    • Zhang L, Shi Y, Wang Y, Zhu F, Wang Q, Ma C et al. The unique expression profile of human TIPE2 suggests new functions beyond its role in immune regulation. Mol Immunol 2011; 48: 1209-1215.
    • (2011) Mol Immunol , vol.48 , pp. 1209-1215
    • Zhang, L.1    Shi, Y.2    Wang, Y.3    Zhu, F.4    Wang, Q.5    Ma, C.6
  • 36
    • 70350576616 scopus 로고    scopus 로고
    • Down-regulation of TIPE2 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
    • Li D, Song L, Fan Y, Li X, Li Y, Chen J et al. Down-regulation of TIPE2 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. Clin Immunol 2009; 133: 422-427.
    • (2009) Clin Immunol , vol.133 , pp. 422-427
    • Li, D.1    Song, L.2    Fan, Y.3    Li, X.4    Li, Y.5    Chen, J.6
  • 37
    • 42949098526 scopus 로고    scopus 로고
    • TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis
    • Sun H, Gong S, Carmody RJ, Hilliard A, Li L, Sun J et al. TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis. Cell 2008; 133: 415-426.
    • (2008) Cell , vol.133 , pp. 415-426
    • Sun, H.1    Gong, S.2    Carmody, R.J.3    Hilliard, A.4    Li, L.5    Sun, J.6
  • 38
  • 39
    • 84862689246 scopus 로고    scopus 로고
    • DNA damage induces NF-kappaBdependent microRNA-21 up-regulation and promotes breast cancer cell invasion
    • Niu J, Shi Y, Tan G, Yang CH, Fan M, Pfeffer LM et al. DNA damage induces NF-kappaBdependent microRNA-21 up-regulation and promotes breast cancer cell invasion. J Biol Chem 2012; 287: 21783-21795.
    • (2012) J Biol Chem , vol.287 , pp. 21783-21795
    • Niu, J.1    Shi, Y.2    Tan, G.3    Yang, C.H.4    Fan, M.5    Pfeffer, L.M.6
  • 40
    • 77953530401 scopus 로고    scopus 로고
    • The transcriptional regulation of miR-21, its multiple transcripts, and their implication in prostate cancer
    • Ribas J, Lupold SE. The transcriptional regulation of miR-21, its multiple transcripts, and their implication in prostate cancer. Cell Cycle 2010; 9: 923-929.
    • (2010) Cell Cycle , vol.9 , pp. 923-929
    • Ribas, J.1    Lupold, S.E.2
  • 41
    • 79251584345 scopus 로고    scopus 로고
    • NF-kappaB targets miR-16 and miR-21 in gastric cancer: Involvement of prostaglandin E receptors
    • Shin VY, Jin H, Ng EK, Cheng AS, Chong WW, Wong CY et al. NF-kappaB targets miR-16 and miR-21 in gastric cancer: Involvement of prostaglandin E receptors. Carcinogenesis 2011; 32: 240-245.
    • (2011) Carcinogenesis , vol.32 , pp. 240-245
    • Shin, V.Y.1    Jin, H.2    Ng, E.K.3    Cheng, A.S.4    Chong, W.W.5    Wong, C.Y.6
  • 42
    • 42249090353 scopus 로고    scopus 로고
    • MiR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism
    • Fujita S, Ito T, Mizutani T, Minoguchi S, Yamamichi N, Sakurai K et al. miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism. J Mol Biol 2008; 378: 492-504.
    • (2008) J Mol Biol , vol.378 , pp. 492-504
    • Fujita, S.1    Ito, T.2    Mizutani, T.3    Minoguchi, S.4    Yamamichi, N.5    Sakurai, K.6
  • 43
    • 77955992756 scopus 로고    scopus 로고
    • STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer
    • Iliopoulos D, Jaeger SA, Hirsch HA, Bulyk ML, Struhl K. STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Mol Cell 2010; 39: 493-506.
    • (2010) Mol Cell , vol.39 , pp. 493-506
    • Iliopoulos, D.1    Jaeger, S.A.2    Hirsch, H.A.3    Bulyk, M.L.4    Struhl, K.5
  • 44
    • 79951469197 scopus 로고    scopus 로고
    • AP-1-Dependent miR-21 expression contributes to chemoresistance in cancer stem cell-like SP cells
    • Misawa A, Katayama R, Koike S, Tomida A, Watanabe T, Fujita N. AP-1-Dependent miR-21 expression contributes to chemoresistance in cancer stem cell-like SP cells. Oncol Res 2010; 19: 23-33.
    • (2010) Oncol Res , vol.19 , pp. 23-33
    • Misawa, A.1    Katayama, R.2    Koike, S.3    Tomida, A.4    Watanabe, T.5    Fujita, N.6
  • 45
    • 84878351462 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription (STAT)-3 regulates microRNA gene expression in chronic lymphocytic leukemia cells
    • Rozovski U, Calin GA, Setoyama T, D'Abundo L, Harris DM, Li P et al. Signal transducer and activator of transcription (STAT)-3 regulates microRNA gene expression in chronic lymphocytic leukemia cells. Mol Cancer 2013; 12: 50.
    • (2013) Mol Cancer , vol.12 , pp. 50
    • Rozovski, U.1    Calin, G.A.2    Setoyama, T.3    D'Abundo, L.4    Harris, D.M.5    Li, P.6
  • 46
    • 81255205360 scopus 로고    scopus 로고
    • Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis
    • Darido C, Georgy SR, Wilanowski T, Dworkin S, Auden A, Zhao Q et al. Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell 2011; 20: 635-648.
    • (2011) Cancer Cell , vol.20 , pp. 635-648
    • Darido, C.1    Georgy, S.R.2    Wilanowski, T.3    Dworkin, S.4    Auden, A.5    Zhao, Q.6
  • 47
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    • Frankel LB, Christoffersen NR, Jacobsen A, Lindow M, Krogh A, Lund AH. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 2008; 283: 1026-1033.
    • (2008) J Biol Chem , vol.283 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 48
    • 78751517914 scopus 로고    scopus 로고
    • Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty
    • Frey MR, Carraro G, Batra RK, Polk DB, Warburton D. Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty. Cancer Biol Ther 2011; 11: 122-124.
    • (2011) Cancer Biol Ther , vol.11 , pp. 122-124
    • Frey, M.R.1    Carraro, G.2    Batra, R.K.3    Polk, D.B.4    Warburton, D.5
  • 49
    • 79957611696 scopus 로고    scopus 로고
    • Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas
    • Kwak HJ, Kim YJ, Chun KR, Woo YM, Park SJ, Jeong JA et al. Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas. Oncogene 2011; 30: 2433-2442.
    • (2011) Oncogene , vol.30 , pp. 2433-2442
    • Kwak, H.J.1    Kim, Y.J.2    Chun, K.R.3    Woo, Y.M.4    Park, S.J.5    Jeong, J.A.6
  • 50
    • 68149137764 scopus 로고    scopus 로고
    • Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma
    • Liu M, Wu H, Liu T, Li Y, Wang F, Wan H et al. Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma. Cell Res 2009; 19: 828-837.
    • (2009) Cell Res , vol.19 , pp. 828-837
    • Liu, M.1    Wu, H.2    Liu, T.3    Li, Y.4    Wang, F.5    Wan, H.6
  • 52
    • 79951803234 scopus 로고    scopus 로고
    • MiR-21 downregulates the tumor suppressor P12 CDK2AP1 and stimulates cell proliferation and invasion
    • Zheng J, Xue H, Wang T, Jiang Y, Liu B, Li J et al. miR-21 downregulates the tumor suppressor P12 CDK2AP1 and stimulates cell proliferation and invasion. J Cell Biochem 2011; 112: 872-880.
    • (2011) J Cell Biochem , vol.112 , pp. 872-880
    • Zheng, J.1    Xue, H.2    Wang, T.3    Jiang, Y.4    Liu, B.5    Li, J.6
  • 53
    • 79955527292 scopus 로고    scopus 로고
    • MiR-21 plays an important role in radiation induced carcinogenesis in BALB/c mice by directly targeting the tumor suppressor gene Big-h3
    • Liu C, Li B, Cheng Y, Lin J, Hao J, Zhang S et al. MiR-21 plays an important role in radiation induced carcinogenesis in BALB/c mice by directly targeting the tumor suppressor gene Big-h3. Int J Biol Sci 2011; 7: 347-363.
    • (2011) Int J Biol Sci , vol.7 , pp. 347-363
    • Liu, C.1    Li, B.2    Cheng, Y.3    Lin, J.4    Hao, J.5    Zhang, S.6
  • 54
    • 80053272794 scopus 로고    scopus 로고
    • MiR-21 targets the tumor suppressor RhoB and regulates proliferation, invasion and apoptosis in colorectal cancer cells
    • Liu M, Tang Q, Qiu M, Lang N, Li M, Zheng Y et al. miR-21 targets the tumor suppressor RhoB and regulates proliferation, invasion and apoptosis in colorectal cancer cells. FEBS Lett 2011; 585: 2998-3005.
    • (2011) FEBS Lett , vol.585 , pp. 2998-3005
    • Liu, M.1    Tang, Q.2    Qiu, M.3    Lang, N.4    Li, M.5    Zheng, Y.6
  • 55
    • 80054764011 scopus 로고    scopus 로고
    • PPARalpha is regulated by miR-21 and miR-27b in human liver
    • Kida K, Nakajima M, Mohri T, Oda Y, Takagi S, Fukami T et al. PPARalpha is regulated by miR-21 and miR-27b in human liver. Pharm Res 2011; 28: 2467-2476.
    • (2011) Pharm Res , vol.28 , pp. 2467-2476
    • Kida, K.1    Nakajima, M.2    Mohri, T.3    Oda, Y.4    Takagi, S.5    Fukami, T.6
  • 56
    • 77953563697 scopus 로고    scopus 로고
    • The code within the code: MicroRNAs target coding regions
    • Forman JJ, Coller HA. The code within the code: MicroRNAs target coding regions. Cell Cycle 2010; 9: 1533-1541.
    • (2010) Cell Cycle , vol.9 , pp. 1533-1541
    • Forman, J.J.1    Coller, H.A.2
  • 57
    • 78651302621 scopus 로고    scopus 로고
    • MicroRNA-181a modulates gene expression of zinc finger family members by directly targeting their coding regions
    • Huang S, Wu S, Ding J, Lin J, Wei L, Gu J et al. MicroRNA-181a modulates gene expression of zinc finger family members by directly targeting their coding regions. Nucleic Acids Res 2010; 38: 7211-7218.
    • (2010) Nucleic Acids Res , vol.38 , pp. 7211-7218
    • Huang, S.1    Wu, S.2    Ding, J.3    Lin, J.4    Wei, L.5    Gu, J.6
  • 58
    • 77953225584 scopus 로고    scopus 로고
    • Antisense oligonucleotide against miR-21 inhibits migration and induces apoptosis in leukemic K562 cells
    • Hu H, Li Y, Gu J, Zhu X, Dong D, Yao J et al. Antisense oligonucleotide against miR-21 inhibits migration and induces apoptosis in leukemic K562 cells. Leuk Lymphoma 2010; 51: 694-701.
    • (2010) Leuk Lymphoma , vol.51 , pp. 694-701
    • Hu, H.1    Li, Y.2    Gu, J.3    Zhu, X.4    Dong, D.5    Yao, J.6
  • 59
    • 77957270582 scopus 로고    scopus 로고
    • Anti-miR-21 oligonucleotide sensitizes leukemic K562 cells to arsenic trioxide by inducing apoptosis
    • Li Y, Zhu X, Gu J, Dong D, Yao J, Lin C et al. Anti-miR-21 oligonucleotide sensitizes leukemic K562 cells to arsenic trioxide by inducing apoptosis. Cancer Sci 2010; 101: 948-954.
    • (2010) Cancer Sci , vol.101 , pp. 948-954
    • Li, Y.1    Zhu, X.2    Gu, J.3    Dong, D.4    Yao, J.5    Lin, C.6


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