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Volumn 5, Issue , 2015, Pages

System-wide assembly of pathways and modules hierarchically reveal metabolic mechanism of cerebral ischemia

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BIOLOGICAL MARKER;

EID: 84949293649     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep17068     Document Type: Article
Times cited : (22)

References (66)
  • 1
    • 84873743056 scopus 로고    scopus 로고
    • Homocysteine, heat shock proteins, genistein and vitamins in ischemic stroke-pathogenic and therapeutic implications
    • Banecka, M. Z. et al. Homocysteine, heat shock proteins, genistein and vitamins in ischemic stroke-pathogenic and therapeutic implications. Acta. Biochim. Pol. 59, 495-499 (2012).
    • (2012) Acta. Biochim. Pol , vol.59 , pp. 495-499
    • Banecka, M.Z.1
  • 2
    • 0023770125 scopus 로고
    • Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction
    • Saikku, P. et al. Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction. Lancet 2, 983-985 (1988).
    • (1988) Lancet , vol.2 , pp. 983-985
    • Saikku, P.1
  • 3
    • 0035657709 scopus 로고    scopus 로고
    • Atherosclerosis as an auto-immune disease: An update
    • Wick, G., Perschinka, H., Millonig, G. Atherosclerosis as an auto-immune disease: an update. Trends Immunol. 22, 665-669 (2001).
    • (2001) Trends Immunol , vol.22 , pp. 665-669
    • Wick, G.1    Perschinka, H.2    Millonig, G.3
  • 4
    • 57349170749 scopus 로고    scopus 로고
    • Melatonin attenuates the cerebral ischemic injury via the MEK/ERK/p90RSK/bad signaling cascade
    • Koh, P. O. Melatonin attenuates the cerebral ischemic injury via the MEK/ERK/p90RSK/bad signaling cascade. J. Vet. Med. Sci. 70, 1219-1223 (2008).
    • (2008) J. Vet. Med. Sci , vol.70 , pp. 1219-1223
    • Koh, P.O.1
  • 5
    • 0033028971 scopus 로고    scopus 로고
    • Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning
    • Shamloo, M., Rytter, A., Wieloch, T. Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning. Neuroscience 93, 81-88 (1999).
    • (1999) Neuroscience , vol.93 , pp. 81-88
    • Shamloo, M.1    Rytter, A.2    Wieloch, T.3
  • 6
    • 58149402446 scopus 로고    scopus 로고
    • Hsp27 protects against ischemic brain injury via attenuation of a novel stress-response cascade upstream of mitochondrial cell death signaling
    • Stetler, R. A. et al. Hsp27 protects against ischemic brain injury via attenuation of a novel stress-response cascade upstream of mitochondrial cell death signaling. J. Neurosci. 28, 13038-13055 (2008).
    • (2008) J. Neurosci , vol.28 , pp. 13038-13055
    • Stetler, R.A.1
  • 7
    • 84863083233 scopus 로고    scopus 로고
    • Nicotinamide prevents the down-regulation of MEK/ERK/p90RSK signaling cascade in brain ischemic injury
    • Sung, J. H., Kim, M. O., Koh, P. O. Nicotinamide prevents the down-regulation of MEK/ERK/p90RSK signaling cascade in brain ischemic injury. J. Vet. Med. Sci. 74, 35-41 (2012).
    • (2012) J. Vet. Med. Sci , vol.74 , pp. 35-41
    • Sung, J.H.1    Kim, M.O.2    Koh, P.O.3
  • 8
    • 33845990232 scopus 로고    scopus 로고
    • Neuroprotection of selenite against ischemic brain injury through negatively regulating early activation of ASK1/JNK cascade via activation of PI3K/AKT pathway
    • Wang, Q., Zhang, Q. G., Wu, D. N., Yin, X. H., Zhang, G. Y. Neuroprotection of selenite against ischemic brain injury through negatively regulating early activation of ASK1/JNK cascade via activation of PI3K/AKT pathway. Acta. Pharmacol. Sin. 28, 19-27 (2007).
    • (2007) Acta. Pharmacol. Sin , vol.28 , pp. 19-27
    • Wang, Q.1    Zhang, Q.G.2    Wu, D.N.3    Yin, X.H.4    Zhang, G.Y.5
  • 9
    • 42749097879 scopus 로고    scopus 로고
    • Additive neuroprotection of GABA A and GABA B receptor agonists in cerebral ischemic injury via PI-3K/Akt pathway inhibiting the ASK1-JNK cascade
    • Xu, J., Li, C., Yin, X. H., Zhang, G. Y. Additive neuroprotection of GABA A and GABA B receptor agonists in cerebral ischemic injury via PI-3K/Akt pathway inhibiting the ASK1-JNK cascade. Neuropharmacology. 54, 1029-1040 (2008).
    • (2008) Neuropharmacology , vol.54 , pp. 1029-1040
    • Xu, J.1    Li, C.2    Yin, X.H.3    Zhang, G.Y.4
  • 10
    • 33847041818 scopus 로고    scopus 로고
    • Down-regulation Cdc42 attenuates neuronal apoptosis through inhibiting MLK3/JNK3 cascade during ischemic reperfusion in rat hippocampus
    • Zhao, J., Pei, D. S., Zhang, Q. G., Zhang, G. Y. Down-regulation Cdc42 attenuates neuronal apoptosis through inhibiting MLK3/JNK3 cascade during ischemic reperfusion in rat hippocampus. Cell Signal 19, 831-843 (2007).
    • (2007) Cell Signal , vol.19 , pp. 831-843
    • Zhao, J.1    Pei, D.S.2    Zhang, Q.G.3    Zhang, G.Y.4
  • 11
    • 73949132592 scopus 로고    scopus 로고
    • A possible new diagnostic biomarker in early diagnosis of Alzheimer's disease
    • Kork, F. et al. A possible new diagnostic biomarker in early diagnosis of Alzheimer's disease. Curr. Alzheimer Res. 6, 519-524 (2009).
    • (2009) Curr. Alzheimer Res , vol.6 , pp. 519-524
    • Kork, F.1
  • 12
    • 77956276702 scopus 로고    scopus 로고
    • Quantitative metabolomics by H-NMR and LC-MS/MS confirms altered metabolic pathways in diabetes
    • Lanza, I. R. et al. Quantitative metabolomics by H-NMR and LC-MS/MS confirms altered metabolic pathways in diabetes. PLos One 5, e10538 (2010).
    • (2010) PLos One , vol.5 , pp. e10538
    • Lanza, I.R.1
  • 13
    • 65249113837 scopus 로고    scopus 로고
    • Metabonomic variations in the drug-treated type 2 diabetes mellitus patients and healthy volunteers
    • Bao, Y. et al. Metabonomic variations in the drug-treated type 2 diabetes mellitus patients and healthy volunteers. J. Proteome Res. 8, 1623-1630 (2009).
    • (2009) J. Proteome Res , vol.8 , pp. 1623-1630
    • Bao, Y.1
  • 14
    • 33646198860 scopus 로고    scopus 로고
    • Pharmaco-metabonomic phenotyping and personalized drug treatment
    • Clayton, T. A. et al. Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature 440, 1073-1077 (2006).
    • (2006) Nature , vol.440 , pp. 1073-1077
    • Clayton, T.A.1
  • 15
    • 84907023545 scopus 로고    scopus 로고
    • A metabonomic analysis of the effect of quercetin on toxicity induced by chronic exposure to low-level dichlorvos in rat plasma
    • Zeng Y. et al. A metabonomic analysis of the effect of quercetin on toxicity induced by chronic exposure to low-level dichlorvos in rat plasma. Mol. Biosyst. 10, 2643-2653 (2014).
    • (2014) Mol. Biosyst , vol.10 , pp. 2643-2653
    • Zeng, Y.1
  • 16
    • 84855951360 scopus 로고    scopus 로고
    • NMR analysis of the rat neurochemical changes induced by middle cerebral artery occlusion
    • Mingxing Y. et al. NMR analysis of the rat neurochemical changes induced by middle cerebral artery occlusion. Talanta 88, 136-144 (2012).
    • (2012) Talanta , vol.88 , pp. 136-144
    • Mingxing, Y.1
  • 17
    • 79955465283 scopus 로고    scopus 로고
    • 1H-NMR-based metabolomics study ofcerebralinfarction
    • Jung J. Y. et al. 1H-NMR-based metabolomics study ofcerebralinfarction. Stroke 42, 1282-1288 (2011).
    • (2011) Stroke , vol.42 , pp. 1282-1288
    • Jung, J.Y.1
  • 18
    • 84897132986 scopus 로고    scopus 로고
    • A Network Pharmacology Approach to Understanding the Mechanisms of Action of Traditional Medicine: Bushenhuoxue Formula for Treatment of Chronic Kidney Disease
    • Shi S. H. et al. A Network Pharmacology Approach to Understanding the Mechanisms of Action of Traditional Medicine: Bushenhuoxue Formula for Treatment of Chronic Kidney Disease. PLoS One 9(3), e89123. doi: 10.1371/journal.pone.0089123
    • PLoS One , vol.9 , Issue.3 , pp. e89123
    • Shi, S.H.1
  • 19
    • 84864357761 scopus 로고    scopus 로고
    • Modular pharmacology: The next paradigm in 234 drug discovery
    • Zhong, W. et al. Modular pharmacology: the next paradigm in 234 drug discovery. Expert Opin. Drug Discov. 7, 667-677 (2012).
    • (2012) Expert Opin. Drug Discov , vol.7 , pp. 667-677
    • Zhong, W.1
  • 20
    • 84879713785 scopus 로고    scopus 로고
    • Navigating personalized medicine dependent on modular flexibility
    • Zhong, W., Yong-yan, W. Navigating personalized medicine dependent on modular flexibility. Trends Mol. Med. 19, 393-395 (2013).
    • (2013) Trends Mol. Med , vol.19 , pp. 393-395
    • Zhong, W.1    Yong-Yan, W.2
  • 21
    • 77951969442 scopus 로고    scopus 로고
    • Metscape: A Cytoscape plug-in for visualizing and interpreting metabolomic data in the context of human metabolic networks
    • Gao, J. et al. Metscape: a Cytoscape plug-in for visualizing and interpreting metabolomic data in the context of human metabolic networks. Bioinformatics 26, 971-973 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 971-973
    • Gao, J.1
  • 22
    • 34247622363 scopus 로고    scopus 로고
    • The importance of bottlenecks in protein networks: Correlation with gene essentiality and expression dynamics
    • Yu, H., Kim, P. M., Sprecher, E., Trifonov, V., Gerstein, M. The importance of bottlenecks in protein networks: correlation with gene essentiality and expression dynamics. PLoS Comput. Biol. 3, e59 (2007).
    • (2007) PLoS Comput. Biol , vol.3 , pp. e59
    • Yu, H.1    Kim, P.M.2    Sprecher, E.3    Trifonov, V.4    Gerstein, M.5
  • 23
    • 0041915878 scopus 로고    scopus 로고
    • Vectorial angle method for evaluating the similarity between two chromatographic fingerprints of Chinese herb
    • Wang, L. X., Xiao, H. B., Liang, X. M., Bi, K. S. Vectorial angle method for evaluating the similarity between two chromatographic fingerprints of Chinese herb. Yao Xue Xue Bao. 37, 713-717 (2002).
    • (2002) Yao Xue Xue Bao , vol.37 , pp. 713-717
    • Wang, L.X.1    Xiao, H.B.2    Liang, X.M.3    Bi, K.S.4
  • 24
    • 84877580262 scopus 로고    scopus 로고
    • Structure and dynamics of molecular networks: A novel paradigm of drug discovery (A comprehensive review), Pharmacol
    • Peter, C. et al. Structure and dynamics of molecular networks: A novel paradigm of drug discovery (A comprehensive review), Pharmacol. Therapeut. 138, 333-408 (2013).
    • (2013) Therapeut , vol.138 , pp. 333-408
    • Peter, C.1
  • 25
    • 0034019505 scopus 로고    scopus 로고
    • Neuroprotection and the ischemic cascade
    • Felberg, R. A., Burgin, W. S., Grotta, J. C. Neuroprotection and the ischemic cascade. CNS Spectr. 5, 52-58 (2000).
    • (2000) CNS Spectr , vol.5 , pp. 52-58
    • Felberg, R.A.1    Burgin, W.S.2    Grotta, J.C.3
  • 26
    • 0023132629 scopus 로고
    • The ischemic cascade: Temporal sequence of hemodynamic, electrocardiographic and symptomatic expressions of ischemia
    • Nesto, R. W., Kowalchuk, G. J. The ischemic cascade: temporal sequence of hemodynamic, electrocardiographic and symptomatic expressions of ischemia. Am. J. Cardiol. 59, 23C-30C (1987).
    • (1987) Am. J. Cardiol , vol.59 , pp. 23C-30C
    • Nesto, R.W.1    Kowalchuk, G.J.2
  • 28
    • 84873987487 scopus 로고    scopus 로고
    • Therapeutic use of creatine in brain or heart ischemia: Available data and future perspectives
    • Perasso, L. et al. Therapeutic use of creatine in brain or heart ischemia: available data and future perspectives. Med. Res. Rev. 33, 336-363 (2013).
    • (2013) Med. Res. Rev , vol.33 , pp. 336-363
    • Perasso, L.1
  • 29
    • 41549130338 scopus 로고    scopus 로고
    • The neuroprotective role of creatine
    • Klein, A. M., Ferrante, R. J. The neuroprotective role of creatine. Subcell Biochem. 46, 205-243 (2007).
    • (2007) Subcell Biochem , vol.46 , pp. 205-243
    • Klein, A.M.1    Ferrante, R.J.2
  • 30
    • 84905769382 scopus 로고    scopus 로고
    • Association between serum uric acid and short-term clinical outcome among patients with acute stroke
    • Zhang, X. L., Zhang, T., Peng, Y., Xu, Y., Zhang, Y. H. Association between serum uric acid and short-term clinical outcome among patients with acute stroke. Zhonghua Liu Xing Bing Xue Za Zhi. 33, 529-533 (2012).
    • (2012) Zhonghua Liu Xing Bing Xue Za Zhi , vol.33 , pp. 529-533
    • Zhang, X.L.1    Zhang, T.2    Peng, Y.3    Xu, Y.4    Zhang, Y.H.5
  • 31
    • 77956657765 scopus 로고    scopus 로고
    • High levels of serum uric acid are associated with silent brain infarction
    • Heo, S. H., Lee, S. H. High levels of serum uric acid are associated with silent brain infarction. J. Neurol. Sci. 297, 6-10 (2010).
    • (2010) J. Neurol. Sci , vol.297 , pp. 6-10
    • Heo, S.H.1    Lee, S.H.2
  • 32
    • 77249165739 scopus 로고    scopus 로고
    • Decrease in uric acid in acute ischemic stroke correlates with stroke severity, evolution and outcome
    • Brouns, R. et al. Decrease in uric acid in acute ischemic stroke correlates with stroke severity, evolution and outcome. Clin. Chem. Lab. Med. 48, 383-390 (2010).
    • (2010) Clin. Chem. Lab. Med , vol.48 , pp. 383-390
    • Brouns, R.1
  • 33
    • 18844481589 scopus 로고
    • Prosopinine an alkaloid from Prosopis africana (Legumineous) Its effects on the central and autonomic nervous systems
    • Bourrinet, P., Quevauviller, A. Prosopinine, an alkaloid from Prosopis africana (Legumineous). Its effects on the central and autonomic nervous systems. C. R. Seances Soc. Biol. Fil. 162, 1138-1140 (1968).
    • (1968) C. R. Seances Soc. Biol. Fil , vol.162 , pp. 1138-1140
    • Bourrinet, P.1    Quevauviller, A.2
  • 34
    • 84864365428 scopus 로고    scopus 로고
    • Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes
    • Barber, M. N. et al. Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes. PLoS One. 7, e41456 (2012).
    • (2012) PLoS One , vol.7 , pp. e41456
    • Barber, M.N.1
  • 35
    • 77957032598 scopus 로고    scopus 로고
    • Superoxide is a potential culprit of caspase-3 dependent endothelial cell death induced by lysophosphatidylcholine
    • Park, S., Kim, J. A., Choi, S., Suh, S. H. Superoxide is a potential culprit of caspase-3 dependent endothelial cell death induced by lysophosphatidylcholine. J. Physiol. Pharmacol. 61, 375-381 (2010).
    • (2010) J. Physiol. Pharmacol , vol.61 , pp. 375-381
    • Park, S.1    Kim, J.A.2    Choi, S.3    Suh, S.H.4
  • 36
    • 77950210766 scopus 로고    scopus 로고
    • Luteolin inhibits lysophosphatidylcholine-induced apoptosis in endothelial cells by a calcium/mitocondrion/caspases-dependent pathway
    • Song, J. et al. Luteolin inhibits lysophosphatidylcholine-induced apoptosis in endothelial cells by a calcium/mitocondrion/caspases-dependent pathway. Planta Med. 76, 433-438 (2010).
    • (2010) Planta Med , vol.76 , pp. 433-438
    • Song, J.1
  • 37
    • 84861528131 scopus 로고    scopus 로고
    • Evidence supporting a key role of Lp-PLA2-generated lysophosphatidylcholine in human atherosclerotic plaque inflammation
    • Goncąlves, I. et al. Evidence supporting a key role of Lp-PLA2-generated lysophosphatidylcholine in human atherosclerotic plaque inflammation. Arterioscler. Thromb. Vasc. Biol. 32, 1505-1512 (2012).
    • (2012) Arterioscler. Thromb. Vasc. Biol , vol.32 , pp. 1505-1512
    • Goncąlves, I.1
  • 38
    • 84857659914 scopus 로고    scopus 로고
    • Acetyl-L-carnitine-mediated neuroprotection during hypoxia is attributed to ERK1/2-Nrf2-regulated mitochondrial biosynthesis
    • Hota, K. B., Hota, S. K., Chaurasia, O. P., Singh, S. B. Acetyl-L-carnitine-mediated neuroprotection during hypoxia is attributed to ERK1/2-Nrf2-regulated mitochondrial biosynthesis. Hippocampus 22, 723-736 (2012).
    • (2012) Hippocampus , vol.22 , pp. 723-736
    • Hota, K.B.1    Hota, S.K.2    Chaurasia, O.P.3    Singh, S.B.4
  • 39
    • 77953992146 scopus 로고    scopus 로고
    • Acetyl-L-carnitine reduces the infarct size and striatal glutamate outflow following focal cerebral ischemia in rats
    • Jalal, F. Y., Böhlke, M., Maher, T. J. Acetyl-L-carnitine reduces the infarct size and striatal glutamate outflow following focal cerebral ischemia in rats. Ann. N. Y. Acad. Sci. 1199, 95-104 (2010).
    • (2010) Ann. N. Y. Acad. Sci , vol.1199 , pp. 95-104
    • Jalal, F.Y.1    Böhlke, M.2    Maher, T.J.3
  • 40
    • 0030908696 scopus 로고    scopus 로고
    • Neuroprotective effects of acetyl-L-carnitine after stroke in rats
    • Lolic, M. M., Fiskum, G., Rosenthal, R. E. Neuroprotective effects of acetyl-L-carnitine after stroke in rats. Ann. Emerg. Med. 29, 758-765 (1997).
    • (1997) Ann. Emerg. Med , vol.29 , pp. 758-765
    • Lolic, M.M.1    Fiskum, G.2    Rosenthal, R.E.3
  • 41
    • 61349192173 scopus 로고    scopus 로고
    • Gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia K562 cells
    • Ge, H. et al. Gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia K562 cells. Cell Biol. Int. 33, 402-410 (2009).
    • (2009) Cell Biol. Int , vol.33 , pp. 402-410
    • Ge, H.1
  • 42
    • 33845889736 scopus 로고    scopus 로고
    • Gamma linolenic acid: An antiinflammatory omega-6 fatty acid
    • Kapoor, R., Huang, Y. S. Gamma linolenic acid: an antiinflammatory omega-6 fatty acid. Curr. Pharm. Biotechnol. 7, 531-534 (2006).
    • (2006) Curr. Pharm. Biotechnol , vol.7 , pp. 531-534
    • Kapoor, R.1    Huang, Y.S.2
  • 43
    • 0036163526 scopus 로고    scopus 로고
    • Effects of Hypothermia on excitatory amino acids and metabolism in stroke patients : A microdialysis study
    • Christian, B. et al. Effects of Hypothermia on Excitatory Amino Acids and Metabolism in Stroke Patients : A Microdialysis Study. Stroke 33, 519-524 (2002).
    • (2002) Stroke , vol.33 , pp. 519-524
    • Christian, B.1
  • 44
    • 0022293204 scopus 로고
    • Prostaglandins thromboxane, leukotrienes and the cerebral circulation in health and disease
    • Walker, V., Pickard, J. D. Prostaglandins, thromboxane, leukotrienes and the cerebral circulation in health and disease. Adv. Tech. Stand. Neurosurg. 12, 3-90 (1985).
    • (1985) Adv. Tech. Stand. Neurosurg , vol.12 , pp. 3-90
    • Walker, V.1    Pickard, J.D.2
  • 45
    • 0022372919 scopus 로고
    • Eicosanoids in the central nervous system
    • Leslie, J. B., Watkins, W. D. Eicosanoids in the central nervous system. J. Neurosurg. 63, 659-668 (1985).
    • (1985) J. Neurosurg , vol.63 , pp. 659-668
    • Leslie, J.B.1    Watkins, W.D.2
  • 46
    • 0019775784 scopus 로고
    • Role of prostaglandins and arachidonic acid derivatives in the coupling of cerebral blood flow to cerebral metabolism
    • Pickard, J. D. Role of prostaglandins and arachidonic acid derivatives in the coupling of cerebral blood flow to cerebral metabolism. J. Cereb. Blood Flow Metab. l, 361-384 (1981).
    • (1981) J. Cereb. Blood Flow Metab , vol.1 , pp. 361-384
    • Pickard, J.D.1
  • 47
    • 0021944258 scopus 로고
    • Modulatory effects of prostaglandin D2 E2 F2a on the postsynaptic actions of inhibitory and excitatory amino acids in cerebellar Purkinje cell dendrites in vitro
    • Kimura, H., Okamoto, K. & Sakai, Y. Modulatory effects of prostaglandin D2, E2, F2a on the postsynaptic actions of inhibitory and excitatory amino acids in cerebellar Purkinje cell dendrites "in vitro". Brain Res. 330, 235-244 (1985).
    • (1985) Brain Res , vol.330 , pp. 235-244
    • Kimura, H.1    Okamoto, K.2    Sakai, Y.3
  • 48
    • 0019964717 scopus 로고
    • The effect of incomplete cerebral ischemia on prostaglandin levels in rat brain
    • Shoami, E., Rosenthal, J., Lavy, S. The effect of incomplete cerebral ischemia on prostaglandin levels in rat brain. Stroke 13, 494-499 (1982).
    • (1982) Stroke , vol.13 , pp. 494-499
    • Shoami, E.1    Rosenthal, J.2    Lavy, S.3
  • 50
    • 0021192575 scopus 로고
    • Prostaglandin synthesis and edema formation during reperfusion following experimental brain ischemia
    • Bhakoo, K. K., Crockard, H. A., Lascelles, P. C., Avery, S. F. Prostaglandin synthesis and edema formation during reperfusion following experimental brain ischemia. Stroke 15, 891-895 (1984).
    • (1984) Stroke , vol.15 , pp. 891-895
    • Bhakoo, K.K.1    Crockard, H.A.2    Lascelles, P.C.3    Avery, S.F.4
  • 51
    • 0019194785 scopus 로고
    • Effect of unilateral common carotid artery occlusion on levels of prostaglandins D2 F2 and 6-ketoprostaglandin Fla in gerbil brain
    • Gaudet, R. J., Levine, L. Effect of unilateral common carotid artery occlusion on levels of prostaglandins D2, F2 and 6-ketoprostaglandin Fla in gerbil brain. Stroke 11, 648-652 (1980).
    • (1980) Stroke , vol.11 , pp. 648-652
    • Gaudet, R.J.1    Levine, L.2
  • 52
    • 79954601400 scopus 로고    scopus 로고
    • Significance of Brain Tissue Oxygenation and the Arachidonic Acid Cascade in Stroke
    • Cameron, R., Savita, K. Significance of Brain Tissue Oxygenation and the Arachidonic Acid Cascade in Stroke. Antioxid. Redox. Signal. 14, 1889-1903 (2011). doi: 10.1089/ars.2010.3474.
    • (2011) Antioxid. Redox. Signal , vol.14 , pp. 1889-1903
    • Cameron, R.1    Savita, K.2
  • 53
    • 0019180368 scopus 로고
    • The composition of the Eskimo food in north-western Greenland
    • Bang, H. O., Dyerberg, J., Sinclair, H. M. The composition of the Eskimo food in north-western Greenland. Am. J. Clin. Nutr. 33, 2657-2661 (1980).
    • (1980) Am. J. Clin. Nutr , vol.33 , pp. 2657-2661
    • Bang, H.O.1    Dyerberg, J.2    Sinclair, H.M.3
  • 54
    • 0018152134 scopus 로고
    • Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis
    • Dyerberg, J., Bang, H. O., Stoffersen, E., Moncada, S., Vane, J. R. Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis Lancet 2, 117-119 (1978).
    • (1978) Lancet , vol.2 , pp. 117-119
    • Dyerberg, J.1    Bang, H.O.2    Stoffersen, E.3    Moncada, S.4    Vane, J.R.5
  • 56
    • 79955465283 scopus 로고    scopus 로고
    • 1H-NMR-based metabolomics study of cerebral infarction
    • Jung, J. et al. 1H-NMR-based metabolomics study of cerebral infarction. Stroke 42, 1282-1288 (2011).
    • (2011) Stroke , vol.42 , pp. 1282-1288
    • Jung, J.1
  • 57
    • 0036451194 scopus 로고    scopus 로고
    • Interactions between taurine and ethanol in the central nervous system
    • Olive, M. F. Interactions between taurine and ethanol in the central nervous system. Amino Acids 23 (4), 345-357 (2002).
    • (2002) Amino Acids , vol.23 , Issue.4 , pp. 345-357
    • Olive, M.F.1
  • 58
    • 84906270831 scopus 로고    scopus 로고
    • Dynamic metabolites profile of cerebral ischemia/reperfusion revealed by 1H NMR-based metabolomics contributes to potential biomarkers
    • Wang Y., Wang Y. G., Ma T. F., Li M., Gu S. L. Dynamic metabolites profile of cerebral ischemia/reperfusion revealed by 1H NMR-based metabolomics contributes to potential biomarkers. Int. J. Clin. Exp. Pathol. 7(7), 4067-4075 (2014).
    • (2014) Int. J. Clin. Exp. Pathol , vol.7 , Issue.7 , pp. 4067-4075
    • Wang, Y.1    Wang, Y.G.2    Ma, T.F.3    Li, M.4    Gu, S.L.5
  • 59
    • 0030814276 scopus 로고    scopus 로고
    • Network theory of aging
    • Kirkwood, T. L. et al. Network theory of aging. Exp.Gerontol. 32, 395-399 (1997).
    • (1997) Exp.Gerontol , vol.32 , pp. 395-399
    • Kirkwood, T.L.1
  • 60
    • 32044451325 scopus 로고    scopus 로고
    • Cancer: A Systems Biology disease
    • Hornberg, J. J. et al. Cancer: a Systems Biology disease. Biosystems 83, 81-90 (2006).
    • (2006) Biosystems , vol.83 , pp. 81-90
    • Hornberg, J.J.1
  • 62
    • 84878853330 scopus 로고    scopus 로고
    • Modular pharmacology: Deciphering the interacting structural organization of the targeted networks
    • Wang, Z., Wang, Y. Y. Modular pharmacology: deciphering the interacting structural organization of the targeted networks. Drug Discov. Today. 18, 560-566 (2013).
    • (2013) Drug Discov. Today , vol.18 , pp. 560-566
    • Wang, Z.1    Wang, Y.Y.2
  • 63
    • 0037308505 scopus 로고    scopus 로고
    • Two approaches for metabolic pathway analysis
    • Steffen, K., Jörg, S. Two approaches for metabolic pathway analysis Trends Biotechnol. 21, 64-69 (2003).
    • (2003) Trends Biotechnol , vol.21 , pp. 64-69
    • Steffen, K.1    Jörg, S.2
  • 64
    • 51849151946 scopus 로고    scopus 로고
    • Global Self-Organization of the cellular metabolic structure
    • De La Fuente, I. M. et al. Global self-organization of the cellular metabolic structure. PLoS One. 3, e3100 (2008).
    • (2008) PLoS One , vol.3 , pp. e3100
    • De La Fuente, I.M.1
  • 65
    • 68749118345 scopus 로고    scopus 로고
    • Defining network topologies that can achieve biochemical adaptation
    • Ma, W. et al. Defining network topologies that can achieve biochemical adaptation. Cell 138, 760-773 (2009).
    • (2009) Cell , vol.138 , pp. 760-773
    • Ma, W.1
  • 66
    • 77950983497 scopus 로고    scopus 로고
    • Regulatory crosstalk of the metabolic network
    • Nana-Maria, G., Hans, L., Markus, R. Regulatory crosstalk of the metabolic network. Trends Biochem. Sci. 35, 220-227 (2010).
    • (2010) Trends Biochem. Sci , vol.35 , pp. 220-227
    • Nana-Maria, G.1    Hans, L.2    Markus, R.3


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