-
1
-
-
0141705369
-
AMPA receptormediated neurotoxicity: Role of Ca2+ and desensitization
-
Frandsen, A. & A. Schousboe. 2003. AMPA receptormediated neurotoxicity: role of Ca2+ and desensitization. Neurochem. Res. 28: 1495-1499.
-
(2003)
Neurochem. Res.
, vol.28
, pp. 1495-1499
-
-
Frandsen, A.1
Schousboe, A.2
-
3
-
-
33746531118
-
Reversed actrocytic GLT-1 during ischemia is crucial to excitotoxic death of neurons, but contributes to the survival of astrocytes themselves
-
Kosugi, T. & K. Kawahara. 2006. Reversed actrocytic GLT-1 during ischemia is crucial to excitotoxic death of neurons, but contributes to the survival of astrocytes themselves. Neurochem. Res. 31: 933-943.
-
(2006)
Neurochem. Res.
, vol.31
, pp. 933-943
-
-
Kosugi, T.1
Kawahara, K.2
-
4
-
-
0026523852
-
Differing neurochemical and morphological sequelae of global ischemia: Comparison of single-and multipleinsult paradigms
-
Lin, B., M.Y. Globus, W.D. Dietrich, et al. 1992. Differing neurochemical and morphological sequelae of global ischemia: comparison of single-and multipleinsult paradigms. J. Neurochem. 59: 2213-2223.
-
(1992)
J. Neurochem.
, vol.59
, pp. 2213-2223
-
-
Lin, B.1
Globus, M.Y.2
Dietrich, W.D.3
-
5
-
-
0036914129
-
Acetyl-L-carnitine inducesmuscarinic antinocieption in mice and rats
-
Ghelardini, C., N. Galeotti, M. Calvani, et al. 2002. Acetyl-L-carnitine inducesmuscarinic antinocieption in mice and rats. Neuropharmacology 43: 1180-1187.
-
(2002)
Neuropharmacology
, vol.43
, pp. 1180-1187
-
-
Ghelardini, C.1
Galeotti, N.2
Calvani, M.3
-
6
-
-
4444225469
-
Acetyl-Lcarnitine induces a sustained potentiation of the afterhyperpolarization
-
Lombardo, P., R. Scuri, E. Cataldo, et al. 2004. Acetyl-Lcarnitine induces a sustained potentiation of the afterhyperpolarization. Neuroscience 128: 293-303.
-
(2004)
Neuroscience
, vol.128
, pp. 293-303
-
-
Lombardo, P.1
Scuri, R.2
Cataldo, E.3
-
7
-
-
0028288688
-
Effect of the chronic treatment with L-acetylcarnitine in Down's syndrome
-
De Falco, F.A., E. D'Angelo, G. Grimaldi, et al. 1994. Effect of the chronic treatment with L-acetylcarnitine in Down's syndrome. Clin. Ter. 144: 123-127.
-
(1994)
Clin. Ter.
, vol.144
, pp. 123-127
-
-
De Falco, F.A.1
D'Angelo, E.2
Grimaldi, G.3
-
8
-
-
0023759547
-
Nerve growth factor binding in aged rat central nervous system: Effect of acetyl-L-carnitine
-
Angelucci, L., M.T. Ramacci, G. Taglialatela, et al. 1988. Nerve growth factor binding in aged rat central nervous system: effect of acetyl-L-carnitine. J. Neurosci. Res. 20: 491-496.
-
(1988)
J. Neurosci. Res.
, vol.20
, pp. 491-496
-
-
Angelucci, L.1
Ramacci, M.T.2
Taglialatela, G.3
-
9
-
-
0028049766
-
Dynamic morphology of the synaptic junctional areas during aging: The effect of chronic acetyl-L-carnitine administration
-
Bertoni-Freddari, C., P. Fattoretti, T. Casoli, et al. 1994. Dynamic morphology of the synaptic junctional areas during aging: the effect of chronic acetyl-L-carnitine administration. Brain Res. 656: 359-366.
-
(1994)
Brain Res.
, vol.656
, pp. 359-366
-
-
Bertoni-Freddari, C.1
Fattoretti, P.2
Casoli, T.3
-
11
-
-
0026002366
-
Longtermacetyl-L-carnitine treatment inAlzheimer's disease
-
Spagnoli, A., U. Lucca, G. Menasce, et al. 1991. Longtermacetyl-L- carnitine treatment inAlzheimer's disease. Neurology 41: 1726-1732.
-
(1991)
Neurology
, vol.41
, pp. 1726-1732
-
-
Spagnoli, A.1
Lucca, U.2
Menasce, G.3
-
12
-
-
0026667916
-
Prevention of postischemic canine neurological injury through potentiation of brain energy metabolism by acetyl-L-carnitine
-
discussion 1317-1318
-
Rosenthal, R.E., R. Williams, Y.E. Bogaert, et al. 1992. Prevention of postischemic canine neurological injury through potentiation of brain energy metabolism by acetyl-L-carnitine. Stroke 23: 1312-1317; discussion 1317-1318.
-
(1992)
Stroke
, vol.23
, pp. 1312-1317
-
-
Rosenthal, R.E.1
Williams, R.2
Bogaert, Y.E.3
-
13
-
-
0029986949
-
Primary preventive and secondary interventionary effects of acetyl-L-carnitine on diabetic neuropathy in the bio-breeding Worcester rat
-
Sima, A.A., H. Ristic, A.Merry, et al. 1996. Primary preventive and secondary interventionary effects of acetyl-L-carnitine on diabetic neuropathy in the bio-breeding Worcester rat. J. Clin. Invest. 97: 1900-1907.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1900-1907
-
-
Sima, A.A.1
Ristic, H.2
Merry, A.3
-
14
-
-
29744452133
-
Mechanisms of ischemic neuroprotection by acetyl-Lcarnitine
-
Zanelli, S.A., N.J. Solenski, R.E. Rosenthal, et al. 2005. Mechanisms of ischemic neuroprotection by acetyl-Lcarnitine. Ann. N.Y. Acad. Sci. 1053: 153-161.
-
(2005)
Ann. N.Y. Acad. Sci.
, vol.1053
, pp. 153-161
-
-
Zanelli, S.A.1
Solenski, N.J.2
Rosenthal, R.E.3
-
15
-
-
0028874731
-
Acetyl-L-carnitine attenuates neuronal damage in gerbils with transient forebrain ischemia only when given before the insult
-
Shuaib, A., T. Waqaar, T. Wishart, et al. 1995. Acetyl-L-carnitine attenuates neuronal damage in gerbils with transient forebrain ischemia only when given before the insult. Neurochem. Res. 20: 1021-1025.
-
(1995)
Neurochem. Res.
, vol.20
, pp. 1021-1025
-
-
Shuaib, A.1
Waqaar, T.2
Wishart, T.3
-
16
-
-
0022545394
-
Amodel of focal ischemic stroke in the rat: Reproducible extensive cortical infarction
-
Chen, S.T., C.Y. Hsu, E.L. Hogan, et al. 1986. Amodel of focal ischemic stroke in the rat: reproducible extensive cortical infarction. Stroke 17: 738-743.
-
(1986)
Stroke
, vol.17
, pp. 738-743
-
-
Chen, S.T.1
Hsu, C.Y.2
Hogan, E.L.3
-
17
-
-
0019868418
-
Focal cerebral ischaemia in the rat: I. Description of technique and early neuropathological consequences following middle cerebral artery occlusion
-
Tamura, A., D.I. Graham, J. McCulloch, et al. 1981. Focal cerebral ischaemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J. Cereb. Blood Flow Metab. 1: 53-60. (Pubitemid 12230166)
-
(1981)
Journal of Cerebral Blood Flow and Metabolism
, vol.1
, Issue.1
, pp. 53-60
-
-
Tamura, A.1
Graham, D.I.2
McCulloch, J.3
Teasdale, G.M.4
-
18
-
-
0024494427
-
Reversible middle cerebral artery occlusion without craniectomy in rats
-
Longa, E.Z., P.R. Weinstein, S. Carlson, et al. 1989. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20: 84-91.
-
(1989)
Stroke
, vol.20
, pp. 84-91
-
-
Longa, E.Z.1
Weinstein, P.R.2
Carlson, S.3
-
20
-
-
33947317286
-
Modulation of cardiovascular responses and neurotransmission during peripheral nociception following nNOS antagonism within the periaqueductal gray
-
Karlsson, G.A., K.A. Chaitoff, S. Hossain, et al. 2007. Modulation of cardiovascular responses and neurotransmission during peripheral nociception following nNOS antagonism within the periaqueductal gray. Brain Res. 1143: 150-160.
-
(2007)
Brain Res.
, vol.1143
, pp. 150-160
-
-
Karlsson, G.A.1
Chaitoff, K.A.2
Hossain, S.3
-
21
-
-
34249852075
-
Acute ischemic stroke: Overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia
-
Durukan, A. & T. Tatlisumak. 2007. Acute ischemic stroke: overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia. Pharmacol. Biochem. Behav. 87: 179-197.
-
(2007)
Pharmacol. Biochem. Behav.
, vol.87
, pp. 179-197
-
-
Durukan, A.1
Tatlisumak, T.2
-
22
-
-
0030908696
-
Neuroprotective effects of acetyl-L-carnitine after stroke in rats
-
Lolic, M.M., G. Fiskum & R.E. Rosenthal. 1997. Neuroprotective effects of acetyl-L-carnitine after stroke in rats. Ann. Emerg. Med. 29: 758-765.
-
(1997)
Ann. Emerg. Med.
, vol.29
, pp. 758-765
-
-
Lolic, M.M.1
Fiskum, G.2
Rosenthal, R.E.3
-
23
-
-
26844435654
-
Rodent models of focal stroke: Size, mechanism, and purpose
-
Carmichael, S.T. 2005. Rodent models of focal stroke: size, mechanism, and purpose. NeuroRx 2: 396-409.
-
(2005)
NeuroRx
, vol.2
, pp. 396-409
-
-
Carmichael, S.T.1
-
25
-
-
0027196253
-
Changes in amino acid neurotransmitters and cerebral blood flow in the ischemic penumbral region following middle cerebral artery occlusion in the rat: Correlation with histopathology
-
Takagi, K., M.D. Ginsberg, M.Y. Globus, et al. 1993. Changes in amino acid neurotransmitters and cerebral blood flow in the ischemic penumbral region following middle cerebral artery occlusion in the rat: correlation with histopathology. J.Cereb. Blood FlowMetab. 13: 575-585.
-
(1993)
J.Cereb. Blood FlowMetab.
, vol.13
, pp. 575-585
-
-
Takagi, K.1
Ginsberg, M.D.2
Globus, M.Y.3
-
26
-
-
19544365764
-
The AMPAantagonist talampanel is neuroprotective in rodentmodels of focal cerebral ischemia
-
Erdo, F., P. Berzsenyi & F. Andrasi. 2005. The AMPAantagonist talampanel is neuroprotective in rodentmodels of focal cerebral ischemia. Brain Res. Bull. 66: 43-49.
-
(2005)
Brain Res. Bull.
, vol.66
, pp. 43-49
-
-
Erdo, F.1
Berzsenyi, P.2
Andrasi, F.3
-
27
-
-
0028947743
-
Neuronal necrosis after middle cerebral artery occlusion inWistar rats progresses at different time intervals in the caudoputamen and the cortex
-
discussion 643
-
Garcia, J.H., K.F. Liu & K.L.Ho. 1995.Neuronal necrosis after middle cerebral artery occlusion inWistar rats progresses at different time intervals in the caudoputamen and the cortex. Stroke 26: 636-642; discussion 643.
-
(1995)
Stroke
, vol.26
, pp. 636-642
-
-
Garcia, J.H.1
Liu, K.F.2
Ho, K.L.3
-
28
-
-
0032704063
-
Striatal outflow of adenosine, excitatory amino acids, gammaaminobutyric acid, and taurine in awake freely moving rats after middle cerebral artery occlusion: Correlations with neurological deficit and histopathological damage
-
discussion 2455
-
Melani, A., L. Pantoni, C. Corsi, et al. 1999. Striatal outflow of adenosine, excitatory amino acids, gammaaminobutyric acid, and taurine in awake freely moving rats after middle cerebral artery occlusion: correlations with neurological deficit and histopathological damage. Stroke 30: 2448-2454; discussion 2455.
-
(1999)
Stroke
, vol.30
, pp. 2448-2454
-
-
Melani, A.1
Pantoni, L.2
Corsi, C.3
-
29
-
-
0028959038
-
Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats, Statistical validation
-
discussion 635
-
Garcia, J.H., S. Wagner, K.F. Liu, et al. 1995. Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation. Stroke 26: 627-634; discussion 635.
-
(1995)
Stroke
, vol.26
, pp. 627-634
-
-
Garcia, J.H.1
Wagner, S.2
Liu, K.F.3
-
30
-
-
3242669822
-
Estrogen attenuates neuronal excitability in the insular cortex following middle cerebral artery occlusion
-
Saleh, T.M., B.J. Connell, C. Legge, et al. 2004. Estrogen attenuates neuronal excitability in the insular cortex following middle cerebral artery occlusion. Brain Res. 1018: 119-129.
-
(2004)
Brain Res.
, vol.1018
, pp. 119-129
-
-
Saleh, T.M.1
Connell, B.J.2
Legge, C.3
-
31
-
-
0025774025
-
Calcium-dependent glutamate release concomitant with massive potassium flux during cerebral ischemia in vivo
-
Katayama, Y., T. Kawamata, T. Tamura, et al. 1991. Calcium-dependent glutamate release concomitant with massive potassium flux during cerebral ischemia in vivo. Brain Res. 558: 136-140.
-
(1991)
Brain Res.
, vol.558
, pp. 136-140
-
-
Katayama, Y.1
Kawamata, T.2
Tamura, T.3
-
32
-
-
0032957182
-
Inhibition of ischemia-induced glutamate release in rat striatum by dihydrokinate and an anion channel blocker
-
Seki, Y., P.J. Feustel, R.W.Keller, Jr., et al. 1999. Inhibition of ischemia-induced glutamate release in rat striatum by dihydrokinate and an anion channel blocker. Stroke 30: 433-440.
-
(1999)
Stroke
, vol.30
, pp. 433-440
-
-
Seki, Y.1
Feustel, P.J.2
Keller Jr., R.W.3
-
33
-
-
0034674519
-
Transporter reversal as a mechanism of glutamate release from the ischemic rat cerebral cortex: Studieswithdl-threo-betabenzyloxyaspartate
-
Phillis, J.W., J. Ren & M.H. O'Regan. 2000. Transporter reversal as a mechanism of glutamate release from the ischemic rat cerebral cortex: studieswithDL-threo-betabenzyloxyaspartate. Brain Res. 868: 105-112.
-
(2000)
Brain Res.
, vol.868
, pp. 105-112
-
-
Phillis, J.W.1
Ren, J.2
O'Regan, M.H.3
-
34
-
-
28444491492
-
Role of glutamate transporters in the clearance and release of glutamate during ischemia and its relation to neuronal death
-
Camacho, A.&L.Massieu. 2006.Role of glutamate transporters in the clearance and release of glutamate during ischemia and its relation to neuronal death. Arch. Med. Res. 37: 11-18.
-
(2006)
Arch. Med. Res.
, vol.37
, pp. 11-18
-
-
Camacho, A.1
Massieu, L.2
-
35
-
-
0034688312
-
Glutamate release in severe brain ischaemia is mainly by reversed uptake
-
Rossi, D.J., T. Oshima & D. Attwell. 2000. Glutamate release in severe brain ischaemia is mainly by reversed uptake. Nature 403: 316-321.
-
(2000)
Nature
, vol.403
, pp. 316-321
-
-
Rossi, D.J.1
Oshima, T.2
Attwell, D.3
-
36
-
-
0021829328
-
Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro
-
Drejer, J., H. Benveniste, N.H. Diemer, et al. 1985. Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro. J. Neurochem. 45: 145-151.
-
(1985)
J. Neurochem.
, vol.45
, pp. 145-151
-
-
Drejer, J.1
Benveniste, H.2
Diemer, N.H.3
-
37
-
-
0022980566
-
Effects of ischemia-like conditions on cultured neurons: Protection by low Na+, lowCa2+ solutions
-
Goldberg, W.J., R.M. Kadingo & J.N. Barrett. 1986. Effects of ischemia-like conditions on cultured neurons: protection by low Na+, lowCa2+ solutions. J. Neurosci. 6: 3144-3151.
-
(1986)
J. Neurosci.
, vol.6
, pp. 3144-3151
-
-
Goldberg, W.J.1
Kadingo, R.M.2
Barrett, J.N.3
-
38
-
-
0026482507
-
Astrocyte glutamate uptake during chemical hypoxia in vitro
-
Swanson, R.A. 1992. Astrocyte glutamate uptake during chemical hypoxia in vitro. Neurosci. Lett. 147: 143-146.
-
(1992)
Neurosci. Lett.
, vol.147
, pp. 143-146
-
-
Swanson, R.A.1
-
39
-
-
13344286293
-
Knockout of glutamate transporters reveals a major role for astroglial transport inexcitotoxicity andclearance of glutamate
-
Rothstein, J.D., M. Dykes-Hoberg, C.A. Pardo, et al. 1996. Knockout of glutamate transporters reveals a major role for astroglial transport inexcitotoxicity andclearance of glutamate. Neuron 16: 675-686.
-
(1996)
Neuron
, vol.16
, pp. 675-686
-
-
Rothstein, J.D.1
Dykes-Hoberg, M.2
Pardo, C.A.3
-
40
-
-
33847235392
-
Role of astrocytes in grey matter during stroke: A modelling approach
-
Dronne, M.A., E. Grenier, T. Dumont, et al. 2007. Role of astrocytes in grey matter during stroke: a modelling approach. Brain Res. 1138: 231-242.
-
(2007)
Brain Res.
, vol.1138
, pp. 231-242
-
-
Dronne, M.A.1
Grenier, E.2
Dumont, T.3
-
41
-
-
0028896256
-
Excitatory amino acid release from astrocytes during energy failure by reversal of sodium-dependent uptake
-
Longuemare, M.C. & R.A. Swanson. 1995. Excitatory amino acid release from astrocytes during energy failure by reversal of sodium-dependent uptake. J.Neurosci. Res. 40: 379-386.
-
(1995)
J.Neurosci. Res.
, vol.40
, pp. 379-386
-
-
Longuemare, M.C.1
Swanson, R.A.2
-
42
-
-
19944428649
-
Betalactam antibiotics offer neuroprotection by increasing glutamate transporter expression
-
Rothstein, J.D., S. Patel, M.R. Regan, et al. 2005. Betalactam antibiotics offer neuroprotection by increasing glutamate transporter expression. Nature 433: 73-77.
-
(2005)
Nature
, vol.433
, pp. 73-77
-
-
Rothstein, J.D.1
Patel, S.2
Regan, M.R.3
-
43
-
-
33845932770
-
Pharmacological induction of ischemic tolerance by glutamate transporter-1 (EAAT2) upregulation
-
Chu, K., S.T. Lee, D.I. Sinn, et al. 2007. Pharmacological induction of ischemic tolerance by glutamate transporter-1 (EAAT2) upregulation. Stroke 38: 177-182.
-
(2007)
Stroke
, vol.38
, pp. 177-182
-
-
Chu, K.1
Lee, S.T.2
Sinn, D.I.3
-
44
-
-
0032978522
-
Reduction in the MK-801 binding sites of the NMDA sub-type of glutamate receptor in amouse model of congenital hyperammonemia: Prevention by acetyl-L-carnitine
-
Rao, K.V. & I.A. Qureshi. 1999. Reduction in the MK-801 binding sites of the NMDA sub-type of glutamate receptor in amouse model of congenital hyperammonemia: prevention by acetyl-L-carnitine. Neuropharmacology 38: 383-394.
-
(1999)
Neuropharmacology
, vol.38
, pp. 383-394
-
-
Rao, K.V.1
Qureshi, I.A.2
-
45
-
-
0028107682
-
Neuroprotective activity of acetyl-L-carnitine: Studies in vitro
-
Forloni, G., N. Angeretti & S. Smiroldo. 1994. Neuroprotective activity of acetyl-L-carnitine: studies in vitro. J. Neurosci. Res. 37: 92-96.
-
(1994)
J. Neurosci. Res.
, vol.37
, pp. 92-96
-
-
Forloni, G.1
Angeretti, N.2
Smiroldo, S.3
-
46
-
-
0031942539
-
Increased formation of reactive oxygen species after permanent and reversible middle cerebral artery occlusion in the rat
-
Peters, O., T. Back, U. Lindauer, et al. 1998. Increased formation of reactive oxygen species after permanent and reversible middle cerebral artery occlusion in the rat. J. Cereb. Blood Flow Metab. 18: 196-205.
-
(1998)
J. Cereb. Blood Flow Metab.
, vol.18
, pp. 196-205
-
-
Peters, O.1
Back, T.2
Lindauer, U.3
-
47
-
-
0032145886
-
Glutamate transporters are oxidant-vulnerable: A molecular link between oxidative and excitotoxic neurodegeneration?
-
Trotti, D., N.C. Danbolt & A. Volterra. 1998. Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol. Sci. 19: 328-334.
-
(1998)
Trends Pharmacol. Sci.
, vol.19
, pp. 328-334
-
-
Trotti, D.1
Danbolt, N.C.2
Volterra, A.3
-
48
-
-
0345269737
-
Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons
-
Rao, S.D.,H.Z. Yin&J.H.Weiss. 2003. Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons. J. Neurosci. 23: 2627-2633.
-
(2003)
J. Neurosci.
, vol.23
, pp. 2627-2633
-
-
Rao, S.D.1
Yin, H.Z.2
Weiss, J.H.3
-
49
-
-
0023747172
-
Systemic acetyl-L-carnitine elevates nigral levels of glutathione and GABA
-
Fariello, R.G., T.N. Ferraro, G.T. Golden, et al. 1988. Systemic acetyl-L-carnitine elevates nigral levels of glutathione and GABA. Life Sci. 43: 289-292.
-
(1988)
Life Sci.
, vol.43
, pp. 289-292
-
-
Fariello, R.G.1
Ferraro, T.N.2
Golden, G.T.3
-
50
-
-
0034009227
-
Neuronal subclass-selective loss of pyruvate dehydrogenase immunoreactivity following canine cardiac arrest and resuscitation
-
Bogaert, Y.E., K.F. Sheu, P.R. Hof, et al. 2000. Neuronal subclass-selective loss of pyruvate dehydrogenase immunoreactivity following canine cardiac arrest and resuscitation. Exp. Neurol. 161: 115-126.
-
(2000)
Exp. Neurol.
, vol.161
, pp. 115-126
-
-
Bogaert, Y.E.1
Sheu, K.F.2
Hof, P.R.3
-
51
-
-
0027517089
-
Inhibition of postcardiac arrest brain protein oxidation by acetyl-L-carnitine
-
Liu, Y., R.E. Rosenthal, P. Starke-Reed, et al. 1993. Inhibition of postcardiac arrest brain protein oxidation by acetyl-L-carnitine. Free Radic. Biol. Med. 15: 667-670.
-
(1993)
Free Radic. Biol. Med.
, vol.15
, pp. 667-670
-
-
Liu, Y.1
Rosenthal, R.E.2
Starke-Reed, P.3
-
52
-
-
14844339380
-
Delayed therapy of experimental global cerebral ischemia with acetyl-L-carnitine in dogs
-
Rosenthal,R.E., Y.E. Bogaert&G. Fiskum. 2005. Delayed therapy of experimental global cerebral ischemia with acetyl-L-carnitine in dogs. Neurosci. Lett. 378: 82-87.
-
(2005)
Neurosci. Lett.
, vol.378
, pp. 82-87
-
-
Rosenthal, R.E.1
Bogaert, Y.E.2
Fiskum, G.3
|