Atherosclerosis as an autoimmune disease: An update

Trends in Immunology

Volumn 22, Issue 12, 2001, Pages 665-669

  Wick, Georg ^a   Perschinka, Hannes ^a   Millonig, Gunda ^b  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^b UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; HEAT SHOCK PROTEIN 60; LOW DENSITY LIPOPROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; METALLOPROTEINASE;

ANTIGENICITY; ARTERY WALL; ATHEROGENESIS; ATHEROSCLEROSIS; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BACTERIUM; CELL ADHESION; CELLULAR IMMUNITY; CROSS REACTION; ENDOTHELIUM CELL; HUMAN; HUMORAL IMMUNITY; INFLAMMATION; MECHANICAL STRESS; MOLECULAR DYNAMICS; NONHUMAN; PARASITE; PATHOGENESIS; PHYLOGENY; PROTEIN BINDING; PROTEIN EXPRESSION; REVIEW; SEQUENCE HOMOLOGY; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, BACTERIAL; ARTERIOSCLEROSIS; AUTOIMMUNE DISEASES; BACTERIAL PROTEINS; CHAPERONIN 60; HUMANS; MOLECULAR SEQUENCE DATA;

EID: 0035657709     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4906(01)02089-0     Document Type: Review

References (46)

1. Is atherosclerosis an immunologically mediated disease?
2. Atherosclerosis, autoimmunity and vascular-associated lymphoid tissue
3. Atherosclerosis - An autoimmune disease
4. Supervising the fold: Functional principles of molecular chaperones
5. Increased expression of HDJ-2 (hsp40) in carotid artery atherosclerosis: A novel heat-shock protein associated with lumenal stenosis and plaque ulceration
6. Balloon angioplasty induces heat-shock protein 70 in human blood vessels
7. Differential distribution of 70 kD heat-shock protein in atherosclerosis. Its potential role in arterial SMC survival
8. Anti-heat-shock-protein 70 kDa antibodies in vascular patients
9. Induction of arteriosclerosis in normocholesterolemic rabbits by immunization with heat-shock protein 65
10. Regression of arteriosclerotic lesions induced by immunization with heat-shock-protein-65-containing material in normocholesterolemic, but not hypercholesterolemic, rabbits
11. Enhanced fatty-streak formation in C57BL/6J mice by immunization with heat-shock protein 65
12. Hyperimmunization of apo-E-deficient mice with homologous malon-dialdehyde low-density lipoprotein suppresses early atherogenesis
13. Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis
14. Endothelial cytotoxicity mediated by serum antibodies to heat-shock proteins of Escherichia coli and Chlamydia pneumoniae: Immune reactions to heat-shock proteins as a possible link between infection and atherosclerosis
15. Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis: Clinical significance determined in a follow-up study
16. Role of infections in atherosclerosis
17. Atherogenic effects of chronic infections: The role of heat-shock protein 60 in autoimmunity
18. Chronic infections and the risk of carotid atherosclerosis: Prospective results from a large population study
19. Chlamydia pneumoniae and atherosclerosis - An update
20. Chlamydial heat-shock protein 60 localizes in human atheroma and regulates macrophage tumor necrosis factor α and matrix metalloproteinase expression
21. Cutting edge: Heat-shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells
22. Comparative study on antibodies to human and bacterial 60 kDa heat-shock proteins in a large cohort of patients with coronary heart disease and healthy subjects
23. T-lymphocyte lines isolated from atheromatous plaque contain cells capable of responding to Chlamydia antigens
24. Increased expression of heat-shock protein 65 coincides with a population of infiltrating T lymphocytes in atherosclerotic lesions of rabbits specifically responding to heat-shock protein 65
25. Co-expression of ICAM-1, VCAM-1, ELAM-1 and Hsp60 in human arterial and venous endothelial cells in response to cytokines and oxidized low-density lipoproteins
26. Fluid shear stress induces heat-shock protein 60 expression in endothelial cells in vitro and in vivo
27. Surface staining and cytotoxic activity of heat-shock protein 60 antibody in stressed aortic endothelial cells
28. Cell-surface localization of the 60 kDa heat-shock chaperonin protein (hsp60) in mammalian cells
29. Autoantibodies against heat-shock protein 60 mediate endothelial cytotoxicity
30. Macrophage-lysis mediated by autoantibodies to heat-shock protein 65/60
31. Suppressive effects of anti-inflammatory agents on human endothelial-cell activation and induction of heat-shock proteins
32. Quantitative determinations of immunoglobulins and complement components in human aortic atherosclerotic wall
33. Complement receptors and regulatory proteins in human atherosclerotic lesions
34. Lipid and macrophage accumulations in arteries of children and the development of atherosclerosis
35. The sequence of cell and matrix changes in atherosclerotic lesions of coronary arteries in the first forty years of life
36. Immunology of atherosclerosis: Cellular composition and major histocompatibility complex class II antigen expression in aortic intima, fatty streaks and atherosclerotic plaques in young and aged human specimens
37. A previously unrecognized site of local accumulation of mononuclear cells. The vascular-associated lymphoid tissue
38. Polyclonal origin of T lymphocytes in human atherosclerotic plaques
39. In vivo down-regulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein-E-knockout mice
40. Analysis of the cellular composition of the arterial intima with modified en face techniques
41. Network of vascular-associated dendritic cells in intima of healthy young individuals
42. Immunology of atherosclerosis. Demonstration of heat-shock protein 60 expression and T lymphocytes bearing αβ or γδ receptor in human atherosclerotic lesions
43. Recognition of heat-shock proteins and γδ-cell function
44. Heat-shock protein Hsp60-reactive γδ cells: A large, diversified T-lymphocyte subset with highly focused specificity
45. Murine γδ T-lymphocyte recognition of HSP-60: A possible source for bacterial immunity or autoimmunity
46. The multi-factorial pathogenesis of autoimmune disease