메뉴 건너뛰기




Volumn 9781461414001, Issue , 2012, Pages 901-929

Cell-based screening in antibacterial discovery

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84949178337     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4614-1400-1_28     Document Type: Chapter
Times cited : (8)

References (85)
  • 1
    • 0000378637 scopus 로고
    • On the antibacterial action of cultures of a penicillium, with special reference to their use in the isolation of B. influenzae
    • Fleming A (1929) On the antibacterial action of cultures of a penicillium, with special reference to their use in the isolation of B. influenzae. Brit J Exper Pathol 10:226-236
    • (1929) Brit J Exper Pathol , vol.10 , pp. 226-236
    • Fleming, A.1
  • 2
    • 26444526660 scopus 로고
    • The soil as a source of microorganisms antagonistic to disease-producing bacteria
    • Waksman SA, Woodruff HB (1940) The soil as a source of microorganisms antagonistic to disease-producing bacteria. J Bacteriol 40:581-600
    • (1940) J Bacteriol , vol.40 , pp. 581-600
    • Waksman, S.A.1    Woodruff, H.B.2
  • 4
    • 0033585711 scopus 로고    scopus 로고
    • The Nobel chronicles. 1939: Gerhard Domagk (1895-1964)
    • Raju T (1999) The Nobel chronicles. 1939: Gerhard Domagk (1895-1964). Lancet 353:681
    • (1999) Lancet , vol.353 , pp. 681
    • Raju, T.1
  • 5
    • 53249128854 scopus 로고    scopus 로고
    • 80th Anniversary of the discovery of penicillin: An appreciation of Sir Alexander Fleming
    • Geddes A (2008) 80th Anniversary of the discovery of penicillin: an appreciation of Sir Alexander Fleming. Int J Antimicrob Agents 32:373
    • (2008) Int J Antimicrob Agents , vol.32 , pp. 373
    • Geddes, A.1
  • 6
    • 0013650593 scopus 로고
    • Penicillin: IX. The laboratory scale production of penicillin in submerged cultures by Penicillium notatum Westling (NRRL 832)
    • Moyer AJ, Goghill RD (1946) Penicillin: IX. The laboratory scale production of penicillin in submerged cultures by Penicillium notatum Westling (NRRL 832). J Bacteriol 51:79-93
    • (1946) J Bacteriol , vol.51 , pp. 79-93
    • Moyer, A.J.1    Goghill, R.D.2
  • 7
    • 84964134387 scopus 로고
    • Streptomycin, a substance exhibiting antibiotic activity against Gram-positive and Gram negative bacteria
    • Schatz A, Bugie E, Waksman SA (1944) Streptomycin, a substance exhibiting antibiotic activity against Gram-positive and Gram negative bacteria. Proc Exptl Biol Med 55:66-69
    • (1944) Proc Exptl Biol Med , vol.55 , pp. 66-69
    • Schatz, A.1    Bugie, E.2    Waksman, S.A.3
  • 9
    • 0008783574 scopus 로고
    • Kanamycin: Its discovery
    • Umezawa H (1958) Kanamycin: its discovery. Ann N Y Acad Sci 76:20-26
    • (1958) Ann N y Acad Sci , vol.76 , pp. 20-26
    • Umezawa, H.1
  • 10
    • 0001122866 scopus 로고
    • Neomycin, a new antibiotic active against streptomycin- resistant bacteria, including tuberculosis organisms
    • Waksman SA, Lechevalier HA (1949) Neomycin, a new antibiotic active against streptomycin- resistant bacteria, including tuberculosis organisms. Science 109:305-307
    • (1949) Science , vol.109 , pp. 305-307
    • Waksman, S.A.1    Lechevalier, H.A.2
  • 11
    • 78651002523 scopus 로고
    • Aureomycin; A product of the continuing search for new antibiotics
    • Duggar BM (1948) Aureomycin; a product of the continuing search for new antibiotics. Ann N Y Acad Sci 51:177-181
    • (1948) Ann N y Acad Sci , vol.51 , pp. 177-181
    • Duggar, B.M.1
  • 12
    • 0002833766 scopus 로고
    • Terramycin, a new antibiotic
    • Finlay AC, Hobby GL (1950) Terramycin, a new antibiotic. Science 111:85
    • (1950) Science , vol.111 , pp. 85
    • Finlay, A.C.1    Hobby, G.L.2
  • 13
    • 0000640187 scopus 로고
    • Streptomyces venezuelae, N. Sp., the source of chloromycetin
    • Ehrlich J, Gottlieb D, Burkholder PR et al (1948) Streptomyces venezuelae, N. Sp., the source of chloromycetin. J Bacteriol 56:467-477
    • (1948) J Bacteriol , vol.56 , pp. 467-477
    • Ehrlich, J.1    Gottlieb, D.2    Burkholder, P.R.3
  • 15
    • 47349095931 scopus 로고
    • Rifamycin. XXVI. Derivatives of rifamycin O with high antimicrobial activity
    • Sensi P, Timbal MT, Greco AM (1962) Rifamycin. XXVI. Derivatives of rifamycin O with high antimicrobial activity. Antibiot Chemother 12:488-494
    • (1962) Antibiot Chemother , vol.12 , pp. 488-494
    • Sensi, P.1    Timbal, M.T.2    Greco, A.M.3
  • 17
    • 67849088685 scopus 로고
    • Discovery of drugs from microbiological sources
    • Conover LH (1971) Discovery of drugs from microbiological sources. Adv Chem Drug Discov Ch 3:33-80
    • (1971) Adv Chem Drug Discov Ch , vol.3 , pp. 33-80
    • Conover, L.H.1
  • 18
    • 2342595765 scopus 로고    scopus 로고
    • Trends in antimicrobial drug development: Implications for the future
    • Spellberg B, Powers JH, Brass EP et al (2004) Trends in antimicrobial drug development: implications for the future. Clin Infect Dis 38:1279-1286
    • (2004) Clin Infect Dis , vol.38 , pp. 1279-1286
    • Spellberg, B.1    Powers, J.H.2    Brass, E.P.3
  • 19
    • 33845903833 scopus 로고    scopus 로고
    • Drugs for bad bugs: Confronting the challenges of antibacterial discovery
    • Payne DJ, Gwynn MN, Holmes DJ et al (2007) Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat Rev Drug Discov 6:29-40
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 29-40
    • Payne, D.J.1    Gwynn, M.N.2    Holmes, D.J.3
  • 20
    • 57749107808 scopus 로고    scopus 로고
    • Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America
    • Boucher HW, Talbot GH, Bradley JS et al (2009) Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis 48:1-12
    • (2009) Clin Infect Dis , vol.48 , pp. 1-12
    • Boucher, H.W.1    Talbot, G.H.2    Bradley, J.S.3
  • 21
    • 0031024171 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski CA, Lombardo F, Dominy BW et al (2001) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Del Rev 23:3-25
    • (2001) Adv Drug Del Rev , vol.23 , pp. 3-25
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3
  • 22
    • 35748934487 scopus 로고    scopus 로고
    • The influence of drug-like concepts on decision-making in medicinal chemistry
    • Leeson PD, Springthorpe B (2007) The influence of drug-like concepts on decision-making in medicinal chemistry. Nat Rev Drug Discov 6:881-890
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 881-890
    • Leeson, P.D.1    Springthorpe, B.2
  • 23
    • 0034461768 scopus 로고    scopus 로고
    • Drug-like properties and the causes of poor solubility and poor permeability
    • Lipinski CA (2000) Drug-like properties and the causes of poor solubility and poor permeability. J Pharmacol Toxicol Methods 44:235-249
    • (2000) J Pharmacol Toxicol Methods , vol.44 , pp. 235-249
    • Lipinski, C.A.1
  • 24
    • 43949129098 scopus 로고    scopus 로고
    • Physicochemical properties of antibacterial compounds: Implications for drug discovery
    • O'Shea R, Moser HE (2008) Physicochemical properties of antibacterial compounds: implications for drug discovery. J Med Chem 51:2871-2878
    • (2008) J Med Chem , vol.51 , pp. 2871-2878
    • O'Shea, R.1    Moser, H.E.2
  • 25
    • 45749143172 scopus 로고    scopus 로고
    • Resistance redux. Infectious diseases, antibiotic resistance and the future of mankind
    • Davies J (2008) Resistance redux. Infectious diseases, antibiotic resistance and the future of mankind. EMBO Rep. 9 Suppl 1:S18-21
    • (2008) EMBO Rep. , vol.9 , pp. S18-21
    • Davies, J.1
  • 26
    • 33745019553 scopus 로고    scopus 로고
    • Marcel Faber Roundtable: Is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration
    • Baltz RH (2006) Marcel Faber Roundtable: is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration? J Ind Microbiol Biotechnol 33:507-513
    • (2006) J Ind Microbiol Biotechnol , vol.33 , pp. 507-513
    • Baltz, R.H.1
  • 27
    • 33750468980 scopus 로고    scopus 로고
    • Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screening
    • De La Fuente R, Sonawane ND, Arumainayagam D et al (2006) Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screening. Br J Pharmacol 149:551-559
    • (2006) Br J Pharmacol , vol.149 , pp. 551-559
    • De La Fuente, R.1    Sonawane, N.D.2    Arumainayagam, D.3
  • 28
    • 0036212454 scopus 로고    scopus 로고
    • Evaluation of redox indicators and the use of digital scanners and spectrophotometer for quantification of microbial growth in microplates
    • Gabrielson J, Hart M, Jarelöv A et al (2002) Evaluation of redox indicators and the use of digital scanners and spectrophotometer for quantification of microbial growth in microplates. J Microbiol Methods 50:63-73
    • (2002) J Microbiol Methods , vol.50 , pp. 63-73
    • Gabrielson, J.1    Hart, M.2    Jarelöv, A.3
  • 29
    • 73649122749 scopus 로고    scopus 로고
    • An oldie but a goodie - Cell wall biosynthesis as antibiotic target pathway
    • Schneider T, Sahl HG (2010) An oldie but a goodie - cell wall biosynthesis as antibiotic target pathway. Int J Med Microbiol 300:161-169
    • (2010) Int J Med Microbiol , vol.300 , pp. 161-169
    • Schneider, T.1    Sahl, H.G.2
  • 30
    • 0017143492 scopus 로고
    • Nocardicin A, a new monocyclic b -lactam antibiotic. I. Discovery, isolation and characterization
    • Aoki H, Sakai H, Kohsaka M et al (1976) Nocardicin A, a new monocyclic b -lactam antibiotic. I. Discovery, isolation and characterization. J Antibiot 29:492-500
    • (1976) J Antibiot , vol.29 , pp. 492-500
    • Aoki, H.1    Sakai, H.2    Kohsaka, M.3
  • 31
    • 0017590808 scopus 로고
    • Screening for b -lactam antibiotics using a mutant of Pseudomonas aeruginosa
    • Kitano K, Nara K, Nakao Y (1977) Screening for b -lactam antibiotics using a mutant of Pseudomonas aeruginosa. J Antibiot 30:239-245
    • (1977) J Antibiot , vol.30 , pp. 239-245
    • Kitano, K.1    Nara, K.2    Nakao, Y.3
  • 32
    • 0023722602 scopus 로고
    • Some characteristics of a hypersensitive mutant to b -lactam antibiotics derived from a strain of Staphylococcus aureus
    • Kamogashira T (1988) Some characteristics of a hypersensitive mutant to b -lactam antibiotics derived from a strain of Staphylococcus aureus. Agric Biol Chem 52:1841-1843
    • (1988) Agric Biol Chem , vol.52 , pp. 1841-1843
    • Kamogashira, T.1
  • 33
    • 0023920146 scopus 로고
    • A screening method for cell wall inhibitors using a D-cycloserine hypersensitive mutant
    • Kamogashira T, Takegata S (1988) A screening method for cell wall inhibitors using a D-cycloserine hypersensitive mutant. J Antibiot 41:803-806
    • (1988) J Antibiot , vol.41 , pp. 803-806
    • Kamogashira, T.1    Takegata, S.2
  • 35
    • 0018343188 scopus 로고
    • Thienamycin, a new p-lactam antibiotic. I. Discovery, taxonomy and physical properties
    • Kahan JS, Kahan FM, Goegelman R et al (1979) Thienamycin, a new p-lactam antibiotic. I. Discovery, taxonomy and physical properties. J Antibiot 32:1-12
    • (1979) J Antibiot , vol.32 , pp. 1-12
    • Kahan, J.S.1    Kahan, F.M.2    Goegelman, R.3
  • 36
    • 0019864162 scopus 로고
    • Sulfazecin and isosulfazecin, novel b -lactam antibiotics of bacterial origin
    • Imada A, Kitano K, Kintaka K et al (1981) Sulfazecin and isosulfazecin, novel b -lactam antibiotics of bacterial origin. Nature 289:590-591
    • (1981) Nature , vol.289 , pp. 590-591
    • Imada, A.1    Kitano, K.2    Kintaka, K.3
  • 37
    • 0019462457 scopus 로고
    • Monocyclic b -lactam antibiotics produced by bacteria
    • Sykes RB, Cimarusti CM, Bonner DP et al (1981) Monocyclic b -lactam antibiotics produced by bacteria. Nature 291:489-491
    • (1981) Nature , vol.291 , pp. 489-491
    • Sykes, R.B.1    Cimarusti, C.M.2    Bonner, D.P.3
  • 38
    • 0020077544 scopus 로고
    • Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria
    • Sykes RB, Bonner DP, Bush K et al (1982) Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria. Antimicrob Agents Chemother 21:85-92
    • (1982) Antimicrob Agents Chemother , vol.21 , pp. 85-92
    • Sykes, R.B.1    Bonner, D.P.2    Bush, K.3
  • 39
    • 0023136452 scopus 로고
    • Binding of a non- b -lactam antibiotic to penicillinbinding proteins
    • Nozaki Y, Katayama N, Ono H (1987) Binding of a non- b -lactam antibiotic to penicillinbinding proteins. Nature 325:179-180
    • (1987) Nature , vol.325 , pp. 179-180
    • Nozaki, Y.1    Katayama, N.2    Ono, H.3
  • 40
    • 0024491605 scopus 로고
    • Lactivicin, a naturally occurring non- b -lactam antibiotic having b -lactam-like action: Biological activities and mode of action
    • Nozaki Y, Katayama N, Harada S et al (1989) Lactivicin, a naturally occurring non- b -lactam antibiotic having b -lactam-like action: biological activities and mode of action. J Antibiot 42:84-93
    • (1989) J Antibiot , vol.42 , pp. 84-93
    • Nozaki, Y.1    Katayama, N.2    Harada, S.3
  • 41
    • 0034093654 scopus 로고    scopus 로고
    • Chromogenic plate assay distinguishing bacteriolytic from bacteriostatic activity of an antibiotic agent
    • Mardones G, Venegas A (2000) Chromogenic plate assay distinguishing bacteriolytic from bacteriostatic activity of an antibiotic agent. J Microbiol Methods 40:199-206
    • (2000) J Microbiol Methods , vol.40 , pp. 199-206
    • Mardones, G.1    Venegas, A.2
  • 42
    • 36549089069 scopus 로고    scopus 로고
    • Differential assay for high-throughput screening of antibacterial compounds
    • Falk SP, Ulijasz AT, Weisblum B (2007) Differential assay for high-throughput screening of antibacterial compounds. J Biomol Screen 12:1102-1108
    • (2007) J Biomol Screen , vol.12 , pp. 1102-1108
    • Falk, S.P.1    Ulijasz, A.T.2    Weisblum, B.3
  • 43
    • 0024246790 scopus 로고
    • Lysobactin, a novel antibacterial agent produced by Lysobacter sp. I. Taxonomy, isolation and partial characterization
    • O'Sullivan J, McCullough JE, Tymiak AA et al (1988) Lysobactin, a novel antibacterial agent produced by Lysobacter sp. I. Taxonomy, isolation and partial characterization. J Antibiot 41:1740-1744
    • (1988) J Antibiot , vol.41 , pp. 1740-1744
    • O'Sullivan, J.1    McCullough, J.E.2    Tymiak, A.A.3
  • 44
    • 0022629180 scopus 로고
    • Glycopeptide antibiotics: A mechanism-based screen employing a bacterial cell wall receptor mimetic
    • Rake JB, Gerber R, Mehta RJ et al (1986) Glycopeptide antibiotics: a mechanism-based screen employing a bacterial cell wall receptor mimetic. J Antibiot 39:58-67
    • (1986) J Antibiot , vol.39 , pp. 58-67
    • Rake, J.B.1    Gerber, R.2    Mehta, R.J.3
  • 45
    • 0024511992 scopus 로고
    • A42867, a novel glycopeptide antibiotic
    • Riva E, Gastaldo L, Beretta MG et al (1989) A42867, a novel glycopeptide antibiotic. J Antibiot 42:497-505
    • (1989) J Antibiot , vol.42 , pp. 497-505
    • Riva, E.1    Gastaldo, L.2    Beretta, M.G.3
  • 46
    • 0036215198 scopus 로고    scopus 로고
    • Identification of compounds that inhibit late steps of peptidoglycan synthesis in bacteria
    • DeCenzo M, Kuranda M, Cohen S et al (2002) Identification of compounds that inhibit late steps of peptidoglycan synthesis in bacteria. J Antibiot 55:288-295
    • (2002) J Antibiot , vol.55 , pp. 288-295
    • Decenzo, M.1    Kuranda, M.2    Cohen, S.3
  • 47
    • 29944447456 scopus 로고    scopus 로고
    • Anucleate cell blue assay: A useful tool for identifying novel type II topoisomerase inhibitors
    • Oyamada Y, Ito H, Fujimoto-Nakamura M et al (2006) Anucleate cell blue assay: a useful tool for identifying novel type II topoisomerase inhibitors. Antimicrob Agents Chemother 50:348-350
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 348-350
    • Oyamada, Y.1    Ito, H.2    Fujimoto-Nakamura, M.3
  • 48
    • 13544274210 scopus 로고    scopus 로고
    • MreB actin-mediated segregation of a specific region of a bacterial chromosome
    • Gitai Z, Dye NA, Reisenauer A et al (2005) MreB actin-mediated segregation of a specific region of a bacterial chromosome. Cell 120:329-341
    • (2005) Cell , vol.120 , pp. 329-341
    • Gitai, Z.1    Dye, N.A.2    Reisenauer, A.3
  • 49
    • 0041701451 scopus 로고    scopus 로고
    • Novel S-benzylisothiourea compound that induces spherical cells in Escherichia coli probably by acting on a rod-shape-determining protein(s) other than penicillin-binding protein 2
    • Iwai N, Nagai K, Wachi M (2002) Novel S-benzylisothiourea compound that induces spherical cells in Escherichia coli probably by acting on a rod-shape-determining protein(s) other than penicillin-binding protein 2. Biosci Biotechnol Biochem 66:2658-2662
    • (2002) Biosci Biotechnol Biochem , vol.66 , pp. 2658-2662
    • Iwai, N.1    Nagai, K.2    Wachi, M.3
  • 50
    • 41049085230 scopus 로고    scopus 로고
    • A robust screen for novel antibiotics: Specific knockout of the initiator of bacterial DNA replication
    • Fossum S, De Pascale G, Weigel C et al (2008) A robust screen for novel antibiotics: specific knockout of the initiator of bacterial DNA replication. FEMS Microbiol Lett 281: 210-214
    • (2008) FEMS Microbiol Lett , vol.281 , pp. 210-214
    • Fossum, S.1    De Pascale, G.2    Weigel, C.3
  • 51
    • 0029586501 scopus 로고    scopus 로고
    • The envA permeability/cell division gene of Escherichia coli encodes the second enzyme of lipid A biosynthesis. UDP-3-O-(R-3- hydroxymyristoyl)-N-acetylglucosamine deacetylase
    • 270
    • Young K, Silver LL, Bramhill D et al (270) The envA permeability/cell division gene of Escherichia coli encodes the second enzyme of lipid A biosynthesis. UDP-3-O-(R-3- hydroxymyristoyl)-N-acetylglucosamine deacetylase. J Biol Chem 270:30384-30391
    • J Biol Chem , vol.270 , pp. 30384-30391
    • Young, K.1    Silver, L.L.2    Bramhill, D.3
  • 52
    • 0036096165 scopus 로고    scopus 로고
    • Antibacterial activities and characterization of novel inhibitors of LpxC
    • Clements JM, Coignard F, Johnson I et al (2002) Antibacterial activities and characterization of novel inhibitors of LpxC. Antimicrob Agents Chemother 46:1793-1799
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 1793-1799
    • Clements, J.M.1    Coignard, F.2    Johnson, I.3
  • 53
    • 50249172242 scopus 로고    scopus 로고
    • Determination of antibiotic hypersensitivity among 4000 single gene knockout mutants of Escherichia coli
    • Tamae C, Liu A, Kim K et al (2008) Determination of antibiotic hypersensitivity among 4000 single gene knockout mutants of Escherichia coli. J Bacteriol 190:5981-5988
    • (2008) J Bacteriol , vol.190 , pp. 5981-5988
    • Tamae, C.1    Liu, A.2    Kim, K.3
  • 54
    • 66249114348 scopus 로고    scopus 로고
    • Characterization of the role of the Escherichia coli periplasmic chaperone SurA using differential proteomics
    • Vertommen D, Ruiz N, Leverrier P et al (2009) Characterization of the role of the Escherichia coli periplasmic chaperone SurA using differential proteomics. Proteomics 9:2432-2443
    • (2009) Proteomics , vol.9 , pp. 2432-2443
    • Vertommen, D.1    Ruiz, N.2    Leverrier, P.3
  • 55
    • 0036256037 scopus 로고    scopus 로고
    • An array of target-specific screening strains for antibacterial discovery
    • DeVito JA, Mills JA, Liu VG et al (2002) An array of target-specific screening strains for antibacterial discovery. Nat Biotechnol 20:478-483
    • (2002) Nat Biotechnol , vol.20 , pp. 478-483
    • Devito, J.A.1    Mills, J.A.2    Liu, V.G.3
  • 56
    • 0035929121 scopus 로고    scopus 로고
    • Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA
    • Ji Y, Zhang B, Van SF et al (2001) Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA. Science 293:2266-2299
    • (2001) Science , vol.293 , pp. 2266-2299
    • Ji, Y.1    Zhang, B.2    Van, S.F.3
  • 57
    • 0036271625 scopus 로고    scopus 로고
    • A genome-wide strategy for the identification of essential genes in Staphylococcus aureus
    • Forsyth RA, Haselbeck RJ, Ohlsen KL et al (2002) A genome-wide strategy for the identification of essential genes in Staphylococcus aureus. Mol Microbiol 43:1387-1400
    • (2002) Mol Microbiol , vol.43 , pp. 1387-1400
    • Forsyth, R.A.1    Haselbeck, R.J.2    Ohlsen, K.L.3
  • 59
    • 33748482185 scopus 로고    scopus 로고
    • Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy
    • Singh SB, Jayasuriya H, Ondeyka JG (2006) Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy. J Am Chem Soc 128:11916-11920
    • (2006) J Am Chem Soc , vol.128 , pp. 11916-11920
    • Singh, S.B.1    Jayasuriya, H.2    Ondeyka, J.G.3
  • 60
    • 34250649348 scopus 로고    scopus 로고
    • Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties
    • Wang J, Kodali S, Lee SH et al (2007) Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties. Proc Natl Acad Sci USA 104:7612-7616
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 7612-7616
    • Wang, J.1    Kodali, S.2    Lee, S.H.3
  • 61
    • 0242693130 scopus 로고    scopus 로고
    • Bacterial membrane lipids: Where do we stand
    • Cronan JE (2003) Bacterial membrane lipids: where do we stand? Ann Rev Microbiol 57:203-224
    • (2003) Ann Rev Microbiol , vol.57 , pp. 203-224
    • Cronan, J.E.1
  • 62
    • 34248340854 scopus 로고    scopus 로고
    • Evaluation of the metS and murB loci for antibiotic discovery using targeted antisense RNA expression analysis in Bacillus anthracis
    • Kedar GC, Brown-Driver V, Reyes DR et al (2007) Evaluation of the metS and murB loci for antibiotic discovery using targeted antisense RNA expression analysis in Bacillus anthracis. Antimicrob Agents Chemother 51:1708-1718
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 1708-1718
    • Kedar, G.C.1    Brown-Driver, V.2    Reyes, D.R.3
  • 63
    • 44449179238 scopus 로고    scopus 로고
    • Comparison of the essential cellular functions of the two murA genes of Bacillus anthracis
    • Kedar GC, Brown-Driver V, Reyes DR et al (2008) Comparison of the essential cellular functions of the two murA genes of Bacillus anthracis. Antimicrob Agents Chemother 52: 2009-2013
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 2009-2013
    • Kedar, G.C.1    Brown-Driver, V.2    Reyes, D.R.3
  • 64
    • 69049093794 scopus 로고    scopus 로고
    • A Staphylococcus aureus fitness test platform for mechanism-based profiling of antibacterial compounds
    • Donald RG, Skwish S, Forsyth RA et al (2009) A Staphylococcus aureus fitness test platform for mechanism-based profiling of antibacterial compounds. Chem Biol 16:826-836
    • (2009) Chem Biol , vol.16 , pp. 826-836
    • Donald, R.G.1    Skwish, S.2    Forsyth, R.A.3
  • 65
    • 0033214149 scopus 로고    scopus 로고
    • Genome-wide expression profiling in Escherichia coli K-12
    • Richmond CS, Glasner JD, Mau R et al (1999) Genome-wide expression profiling in Escherichia coli K-12. Nucleic Acids Res 27:3821-3835
    • (1999) Nucleic Acids Res , vol.27 , pp. 3821-3835
    • Richmond, C.S.1    Glasner, J.D.2    Mau, R.3
  • 66
    • 0035154372 scopus 로고    scopus 로고
    • Gene expression changes triggered by exposure of Haemophilus influenzae to novobiocin or ciprofloxacin: Combined transcription and translation analysis
    • Gmuender H, Kuratli K, Di Padova K et al (2001) Gene expression changes triggered by exposure of Haemophilus influenzae to novobiocin or ciprofloxacin: combined transcription and translation analysis. Genome Res 11:28-42
    • (2001) Genome Res , vol.11 , pp. 28-42
    • Gmuender, H.1    Kuratli, K.2    Di Padova, K.3
  • 67
    • 0141925858 scopus 로고    scopus 로고
    • Interfering with different steps of protein synthesis explored by transcriptional profiling of Escherichia coli K-12
    • Sabina J, Dover N, Templeton LJ et al (2003) Interfering with different steps of protein synthesis explored by transcriptional profiling of Escherichia coli K-12. J Bacteriol 185:6158-6170
    • (2003) J Bacteriol , vol.185 , pp. 6158-6170
    • Sabina, J.1    Dover, N.2    Templeton, L.J.3
  • 68
    • 0042697666 scopus 로고    scopus 로고
    • Comparison of the changes in global gene expression of Escherichia coli induced by four bactericidal agents
    • Shaw KJ, Miller N, Liu X et al (2003) Comparison of the changes in global gene expression of Escherichia coli induced by four bactericidal agents. J Mol Microbiol Biotechnol 5:105-122
    • (2003) J Mol Microbiol Biotechnol , vol.5 , pp. 105-122
    • Shaw, K.J.1    Miller, N.2    Liu, X.3
  • 69
    • 12944327876 scopus 로고    scopus 로고
    • Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants
    • Frieberg C, Fischer HP, Brunner NA (2005) Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants. Antimicrob Agents Chemother 49:749-759
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 749-759
    • Frieberg, C.1    Fischer, H.P.2    Brunner, N.A.3
  • 70
    • 0347766000 scopus 로고    scopus 로고
    • Identification of antibiotic stress-inducible promoters: A systematic approach to novel pathway-specific reporter assays for antibacterial drug discovery
    • Fischer HP, Brunner NA, Wieland B et al (2004) Identification of antibiotic stress-inducible promoters: a systematic approach to novel pathway-specific reporter assays for antibacterial drug discovery. Genome Res 14:90-98
    • (2004) Genome Res , vol.14 , pp. 90-98
    • Fischer, H.P.1    Brunner, N.A.2    Wieland, B.3
  • 71
    • 33846125002 scopus 로고    scopus 로고
    • Applications of whole-cell bacterial sensors in biotechnology and environmental science
    • Yagi K (2007) Applications of whole-cell bacterial sensors in biotechnology and environmental science. Appl Microbiol Biotechnol 73:1251-1258
    • (2007) Appl Microbiol Biotechnol , vol.73 , pp. 1251-1258
    • Yagi, K.1
  • 72
    • 0037168560 scopus 로고    scopus 로고
    • Transcriptional modulation of bacterial gene expression by subinhibitory concentrations of antibiotics
    • Goh EB, Yim G, Tsui W et al (2002) Transcriptional modulation of bacterial gene expression by subinhibitory concentrations of antibiotics. Proc Natl Acad Sci USA 99:17025-17030
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 17025-17030
    • Goh, E.B.1    Yim, G.2    Tsui, W.3
  • 73
    • 35748937348 scopus 로고    scopus 로고
    • Stress-activated bioluminescent Escherichia coli sensors for antimicrobial agents detection
    • Shapiro E, Baneyx F (2007) Stress-activated bioluminescent Escherichia coli sensors for antimicrobial agents detection. J Biotechnol 132:487-493
    • (2007) J Biotechnol , vol.132 , pp. 487-493
    • Shapiro, E.1    Baneyx, F.2
  • 74
    • 0032702687 scopus 로고    scopus 로고
    • Stress responses as a tool to detect and characterize the mode of action of antibacterial agents
    • Bianchi A, Baneyx F (1999) Stress responses as a tool to detect and characterize the mode of action of antibacterial agents. Appl Environ Microbiol 65:5023-5027
    • (1999) Appl Environ Microbiol , vol.65 , pp. 5023-5027
    • Bianchi, A.1    Baneyx, F.2
  • 75
    • 0034666679 scopus 로고    scopus 로고
    • Detection and quantification of tetracyclines by whole cell biosensors
    • Hansen LH, Sörensen SJ (2000) Detection and quantification of tetracyclines by whole cell biosensors. FEMS Microbiol Lett 190:273-278
    • (2000) FEMS Microbiol Lett , vol.190 , pp. 273-278
    • Hansen, L.H.1    Sörensen, S.J.2
  • 76
    • 3042621796 scopus 로고    scopus 로고
    • Panel of Bacillus subtilis reporter strains indicative of various modes of action
    • Hutter B, Fischer C, Jacobi A et al (2004) Panel of Bacillus subtilis reporter strains indicative of various modes of action. Antimicrob Agents Chemother 48:2588-2594
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2588-2594
    • Hutter, B.1    Fischer, C.2    Jacobi, A.3
  • 77
    • 35448931532 scopus 로고    scopus 로고
    • Novel whole-cell antibiotic biosensors for compound discovery
    • Urban A, Eckermann S, Fast B et al (2007) Novel whole-cell antibiotic biosensors for compound discovery. Appl Environ Microbiol 73:6436-6443
    • (2007) Appl Environ Microbiol , vol.73 , pp. 6436-6443
    • Urban, A.1    Eckermann, S.2    Fast, B.3
  • 78
    • 3342969325 scopus 로고    scopus 로고
    • Prediction of mechanisms of action of antibacterial compounds by gene expression profiling
    • Hutter B, Schaab C, Albrecht S et al (2004) Prediction of mechanisms of action of antibacterial compounds by gene expression profiling. Antimicrob Agents Chemother 48:2838-2844
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2838-2844
    • Hutter, B.1    Schaab, C.2    Albrecht, S.3
  • 79
    • 0035991865 scopus 로고    scopus 로고
    • Stress-based identification and classification of antibacterial agents: Second-generation Escherichia coli reporter strains and optimization of detection
    • Shapiro E, Baneyx F (2002) Stress-based identification and classification of antibacterial agents: second-generation Escherichia coli reporter strains and optimization of detection. Antimicrob Agents Chemother 46:2490-2497
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 2490-2497
    • Shapiro, E.1    Baneyx, F.2
  • 80
    • 27944432167 scopus 로고    scopus 로고
    • A set of multicolored Photinus pyralis luciferase mutants for in vivo bioluminescence applications
    • Shapiro E, Lu C, Baneyx F (2005) A set of multicolored Photinus pyralis luciferase mutants for in vivo bioluminescence applications. Protein Eng Des Sel 18:581-587
    • (2005) Protein Eng des Sel , vol.18 , pp. 581-587
    • Shapiro, E.1    Lu, C.2    Baneyx, F.3
  • 81
    • 3042670809 scopus 로고    scopus 로고
    • Molecular characterization of benzimidazole resistance in Helicobacter pylori
    • Mills SD, Yang W, MacCormack K (2004) Molecular characterization of benzimidazole resistance in Helicobacter pylori. Antimicrob Agents Chemother 48:2524-2530
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2524-2530
    • Mills, S.D.1    Yang, W.2    Maccormack, K.3
  • 82
    • 27144460621 scopus 로고    scopus 로고
    • Dysregulation of bacterial proteolytic machinery by a new class of antibiotics
    • Brötz-Oesterhelt H, Beyer D, Kroll H-P et al (2005) Dysregulation of bacterial proteolytic machinery by a new class of antibiotics. Nat Med 11:1082-1087
    • (2005) Nat Med , vol.11 , pp. 1082-1087
    • Brötz-Oesterhelt, H.1    Beyer, D.2    Kroll, H.-P.3
  • 83
    • 0035991851 scopus 로고    scopus 로고
    • PCR-based ordered genomic libraries: A new approach to drug target identification for Streptococcus pneumoniae
    • Belanger AE, Lai A, Brackman MA et al (2002) PCR-based ordered genomic libraries: a new approach to drug target identification for Streptococcus pneumoniae. Antimicrob Agents Chemother 46:2507-2512
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 2507-2512
    • Belanger, A.E.1    Lai, A.2    Brackman, M.A.3
  • 84
    • 5444276383 scopus 로고    scopus 로고
    • Multicopy suppressors for novel antibacterial compounds reveal targets and drug efflux susceptibility
    • Li X, Zolli-Juran M, Cechetto JD, Daigle DM et al (2004) Multicopy suppressors for novel antibacterial compounds reveal targets and drug efflux susceptibility. Chem Biol 11: 1423-1430
    • (2004) Chem Biol , vol.11 , pp. 1423-1430
    • Li, X.1    Zolli-Juran, M.2    Cechetto, J.D.3    Daigle, D.M.4
  • 85
    • 48749117988 scopus 로고    scopus 로고
    • Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors
    • Miller AA, Bundy GL, Mott JE et al (2008) Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. Antimicrob Agents Chemother 52:2806-2812
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 2806-2812
    • Miller, A.A.1    Bundy, G.L.2    Mott, J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.