-
1
-
-
0000378637
-
On the antibacterial action of cultures of a penicillium, with special reference to their use in the isolation of B. influenzae
-
Fleming A (1929) On the antibacterial action of cultures of a penicillium, with special reference to their use in the isolation of B. influenzae. Brit J Exper Pathol 10:226-236
-
(1929)
Brit J Exper Pathol
, vol.10
, pp. 226-236
-
-
Fleming, A.1
-
2
-
-
26444526660
-
The soil as a source of microorganisms antagonistic to disease-producing bacteria
-
Waksman SA, Woodruff HB (1940) The soil as a source of microorganisms antagonistic to disease-producing bacteria. J Bacteriol 40:581-600
-
(1940)
J Bacteriol
, vol.40
, pp. 581-600
-
-
Waksman, S.A.1
Woodruff, H.B.2
-
4
-
-
0033585711
-
The Nobel chronicles. 1939: Gerhard Domagk (1895-1964)
-
Raju T (1999) The Nobel chronicles. 1939: Gerhard Domagk (1895-1964). Lancet 353:681
-
(1999)
Lancet
, vol.353
, pp. 681
-
-
Raju, T.1
-
5
-
-
53249128854
-
80th Anniversary of the discovery of penicillin: An appreciation of Sir Alexander Fleming
-
Geddes A (2008) 80th Anniversary of the discovery of penicillin: an appreciation of Sir Alexander Fleming. Int J Antimicrob Agents 32:373
-
(2008)
Int J Antimicrob Agents
, vol.32
, pp. 373
-
-
Geddes, A.1
-
6
-
-
0013650593
-
Penicillin: IX. The laboratory scale production of penicillin in submerged cultures by Penicillium notatum Westling (NRRL 832)
-
Moyer AJ, Goghill RD (1946) Penicillin: IX. The laboratory scale production of penicillin in submerged cultures by Penicillium notatum Westling (NRRL 832). J Bacteriol 51:79-93
-
(1946)
J Bacteriol
, vol.51
, pp. 79-93
-
-
Moyer, A.J.1
Goghill, R.D.2
-
7
-
-
84964134387
-
Streptomycin, a substance exhibiting antibiotic activity against Gram-positive and Gram negative bacteria
-
Schatz A, Bugie E, Waksman SA (1944) Streptomycin, a substance exhibiting antibiotic activity against Gram-positive and Gram negative bacteria. Proc Exptl Biol Med 55:66-69
-
(1944)
Proc Exptl Biol Med
, vol.55
, pp. 66-69
-
-
Schatz, A.1
Bugie, E.2
Waksman, S.A.3
-
8
-
-
84929573055
-
-
Elsevier, Amsterdam
-
Waksman S (1964) Streptomycin: background, isolation, properties, and utilization Nobel Lecture, December 12, 1952 From Nobel Lectures, Physiology or Medicine 1942-1962. Elsevier, Amsterdam
-
(1964)
Streptomycin: Background, Isolation, Properties, and Utilization Nobel Lecture, December 12, 1952 from Nobel Lectures, Physiology or Medicine 1942-1962
-
-
Waksman, S.1
-
9
-
-
0008783574
-
Kanamycin: Its discovery
-
Umezawa H (1958) Kanamycin: its discovery. Ann N Y Acad Sci 76:20-26
-
(1958)
Ann N y Acad Sci
, vol.76
, pp. 20-26
-
-
Umezawa, H.1
-
10
-
-
0001122866
-
Neomycin, a new antibiotic active against streptomycin- resistant bacteria, including tuberculosis organisms
-
Waksman SA, Lechevalier HA (1949) Neomycin, a new antibiotic active against streptomycin- resistant bacteria, including tuberculosis organisms. Science 109:305-307
-
(1949)
Science
, vol.109
, pp. 305-307
-
-
Waksman, S.A.1
Lechevalier, H.A.2
-
11
-
-
78651002523
-
Aureomycin; A product of the continuing search for new antibiotics
-
Duggar BM (1948) Aureomycin; a product of the continuing search for new antibiotics. Ann N Y Acad Sci 51:177-181
-
(1948)
Ann N y Acad Sci
, vol.51
, pp. 177-181
-
-
Duggar, B.M.1
-
12
-
-
0002833766
-
Terramycin, a new antibiotic
-
Finlay AC, Hobby GL (1950) Terramycin, a new antibiotic. Science 111:85
-
(1950)
Science
, vol.111
, pp. 85
-
-
Finlay, A.C.1
Hobby, G.L.2
-
13
-
-
0000640187
-
Streptomyces venezuelae, N. Sp., the source of chloromycetin
-
Ehrlich J, Gottlieb D, Burkholder PR et al (1948) Streptomyces venezuelae, N. Sp., the source of chloromycetin. J Bacteriol 56:467-477
-
(1948)
J Bacteriol
, vol.56
, pp. 467-477
-
-
Ehrlich, J.1
Gottlieb, D.2
Burkholder, P.R.3
-
15
-
-
47349095931
-
Rifamycin. XXVI. Derivatives of rifamycin O with high antimicrobial activity
-
Sensi P, Timbal MT, Greco AM (1962) Rifamycin. XXVI. Derivatives of rifamycin O with high antimicrobial activity. Antibiot Chemother 12:488-494
-
(1962)
Antibiot Chemother
, vol.12
, pp. 488-494
-
-
Sensi, P.1
Timbal, M.T.2
Greco, A.M.3
-
17
-
-
67849088685
-
Discovery of drugs from microbiological sources
-
Conover LH (1971) Discovery of drugs from microbiological sources. Adv Chem Drug Discov Ch 3:33-80
-
(1971)
Adv Chem Drug Discov Ch
, vol.3
, pp. 33-80
-
-
Conover, L.H.1
-
18
-
-
2342595765
-
Trends in antimicrobial drug development: Implications for the future
-
Spellberg B, Powers JH, Brass EP et al (2004) Trends in antimicrobial drug development: implications for the future. Clin Infect Dis 38:1279-1286
-
(2004)
Clin Infect Dis
, vol.38
, pp. 1279-1286
-
-
Spellberg, B.1
Powers, J.H.2
Brass, E.P.3
-
19
-
-
33845903833
-
Drugs for bad bugs: Confronting the challenges of antibacterial discovery
-
Payne DJ, Gwynn MN, Holmes DJ et al (2007) Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat Rev Drug Discov 6:29-40
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 29-40
-
-
Payne, D.J.1
Gwynn, M.N.2
Holmes, D.J.3
-
20
-
-
57749107808
-
Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America
-
Boucher HW, Talbot GH, Bradley JS et al (2009) Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis 48:1-12
-
(2009)
Clin Infect Dis
, vol.48
, pp. 1-12
-
-
Boucher, H.W.1
Talbot, G.H.2
Bradley, J.S.3
-
21
-
-
0031024171
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
Lipinski CA, Lombardo F, Dominy BW et al (2001) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Del Rev 23:3-25
-
(2001)
Adv Drug Del Rev
, vol.23
, pp. 3-25
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
-
22
-
-
35748934487
-
The influence of drug-like concepts on decision-making in medicinal chemistry
-
Leeson PD, Springthorpe B (2007) The influence of drug-like concepts on decision-making in medicinal chemistry. Nat Rev Drug Discov 6:881-890
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 881-890
-
-
Leeson, P.D.1
Springthorpe, B.2
-
23
-
-
0034461768
-
Drug-like properties and the causes of poor solubility and poor permeability
-
Lipinski CA (2000) Drug-like properties and the causes of poor solubility and poor permeability. J Pharmacol Toxicol Methods 44:235-249
-
(2000)
J Pharmacol Toxicol Methods
, vol.44
, pp. 235-249
-
-
Lipinski, C.A.1
-
24
-
-
43949129098
-
Physicochemical properties of antibacterial compounds: Implications for drug discovery
-
O'Shea R, Moser HE (2008) Physicochemical properties of antibacterial compounds: implications for drug discovery. J Med Chem 51:2871-2878
-
(2008)
J Med Chem
, vol.51
, pp. 2871-2878
-
-
O'Shea, R.1
Moser, H.E.2
-
25
-
-
45749143172
-
Resistance redux. Infectious diseases, antibiotic resistance and the future of mankind
-
Davies J (2008) Resistance redux. Infectious diseases, antibiotic resistance and the future of mankind. EMBO Rep. 9 Suppl 1:S18-21
-
(2008)
EMBO Rep.
, vol.9
, pp. S18-21
-
-
Davies, J.1
-
26
-
-
33745019553
-
Marcel Faber Roundtable: Is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration
-
Baltz RH (2006) Marcel Faber Roundtable: is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration? J Ind Microbiol Biotechnol 33:507-513
-
(2006)
J Ind Microbiol Biotechnol
, vol.33
, pp. 507-513
-
-
Baltz, R.H.1
-
27
-
-
33750468980
-
Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screening
-
De La Fuente R, Sonawane ND, Arumainayagam D et al (2006) Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screening. Br J Pharmacol 149:551-559
-
(2006)
Br J Pharmacol
, vol.149
, pp. 551-559
-
-
De La Fuente, R.1
Sonawane, N.D.2
Arumainayagam, D.3
-
28
-
-
0036212454
-
Evaluation of redox indicators and the use of digital scanners and spectrophotometer for quantification of microbial growth in microplates
-
Gabrielson J, Hart M, Jarelöv A et al (2002) Evaluation of redox indicators and the use of digital scanners and spectrophotometer for quantification of microbial growth in microplates. J Microbiol Methods 50:63-73
-
(2002)
J Microbiol Methods
, vol.50
, pp. 63-73
-
-
Gabrielson, J.1
Hart, M.2
Jarelöv, A.3
-
29
-
-
73649122749
-
An oldie but a goodie - Cell wall biosynthesis as antibiotic target pathway
-
Schneider T, Sahl HG (2010) An oldie but a goodie - cell wall biosynthesis as antibiotic target pathway. Int J Med Microbiol 300:161-169
-
(2010)
Int J Med Microbiol
, vol.300
, pp. 161-169
-
-
Schneider, T.1
Sahl, H.G.2
-
30
-
-
0017143492
-
Nocardicin A, a new monocyclic b -lactam antibiotic. I. Discovery, isolation and characterization
-
Aoki H, Sakai H, Kohsaka M et al (1976) Nocardicin A, a new monocyclic b -lactam antibiotic. I. Discovery, isolation and characterization. J Antibiot 29:492-500
-
(1976)
J Antibiot
, vol.29
, pp. 492-500
-
-
Aoki, H.1
Sakai, H.2
Kohsaka, M.3
-
31
-
-
0017590808
-
Screening for b -lactam antibiotics using a mutant of Pseudomonas aeruginosa
-
Kitano K, Nara K, Nakao Y (1977) Screening for b -lactam antibiotics using a mutant of Pseudomonas aeruginosa. J Antibiot 30:239-245
-
(1977)
J Antibiot
, vol.30
, pp. 239-245
-
-
Kitano, K.1
Nara, K.2
Nakao, Y.3
-
32
-
-
0023722602
-
Some characteristics of a hypersensitive mutant to b -lactam antibiotics derived from a strain of Staphylococcus aureus
-
Kamogashira T (1988) Some characteristics of a hypersensitive mutant to b -lactam antibiotics derived from a strain of Staphylococcus aureus. Agric Biol Chem 52:1841-1843
-
(1988)
Agric Biol Chem
, vol.52
, pp. 1841-1843
-
-
Kamogashira, T.1
-
33
-
-
0023920146
-
A screening method for cell wall inhibitors using a D-cycloserine hypersensitive mutant
-
Kamogashira T, Takegata S (1988) A screening method for cell wall inhibitors using a D-cycloserine hypersensitive mutant. J Antibiot 41:803-806
-
(1988)
J Antibiot
, vol.41
, pp. 803-806
-
-
Kamogashira, T.1
Takegata, S.2
-
35
-
-
0018343188
-
Thienamycin, a new p-lactam antibiotic. I. Discovery, taxonomy and physical properties
-
Kahan JS, Kahan FM, Goegelman R et al (1979) Thienamycin, a new p-lactam antibiotic. I. Discovery, taxonomy and physical properties. J Antibiot 32:1-12
-
(1979)
J Antibiot
, vol.32
, pp. 1-12
-
-
Kahan, J.S.1
Kahan, F.M.2
Goegelman, R.3
-
36
-
-
0019864162
-
Sulfazecin and isosulfazecin, novel b -lactam antibiotics of bacterial origin
-
Imada A, Kitano K, Kintaka K et al (1981) Sulfazecin and isosulfazecin, novel b -lactam antibiotics of bacterial origin. Nature 289:590-591
-
(1981)
Nature
, vol.289
, pp. 590-591
-
-
Imada, A.1
Kitano, K.2
Kintaka, K.3
-
37
-
-
0019462457
-
Monocyclic b -lactam antibiotics produced by bacteria
-
Sykes RB, Cimarusti CM, Bonner DP et al (1981) Monocyclic b -lactam antibiotics produced by bacteria. Nature 291:489-491
-
(1981)
Nature
, vol.291
, pp. 489-491
-
-
Sykes, R.B.1
Cimarusti, C.M.2
Bonner, D.P.3
-
38
-
-
0020077544
-
Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria
-
Sykes RB, Bonner DP, Bush K et al (1982) Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria. Antimicrob Agents Chemother 21:85-92
-
(1982)
Antimicrob Agents Chemother
, vol.21
, pp. 85-92
-
-
Sykes, R.B.1
Bonner, D.P.2
Bush, K.3
-
39
-
-
0023136452
-
Binding of a non- b -lactam antibiotic to penicillinbinding proteins
-
Nozaki Y, Katayama N, Ono H (1987) Binding of a non- b -lactam antibiotic to penicillinbinding proteins. Nature 325:179-180
-
(1987)
Nature
, vol.325
, pp. 179-180
-
-
Nozaki, Y.1
Katayama, N.2
Ono, H.3
-
40
-
-
0024491605
-
Lactivicin, a naturally occurring non- b -lactam antibiotic having b -lactam-like action: Biological activities and mode of action
-
Nozaki Y, Katayama N, Harada S et al (1989) Lactivicin, a naturally occurring non- b -lactam antibiotic having b -lactam-like action: biological activities and mode of action. J Antibiot 42:84-93
-
(1989)
J Antibiot
, vol.42
, pp. 84-93
-
-
Nozaki, Y.1
Katayama, N.2
Harada, S.3
-
41
-
-
0034093654
-
Chromogenic plate assay distinguishing bacteriolytic from bacteriostatic activity of an antibiotic agent
-
Mardones G, Venegas A (2000) Chromogenic plate assay distinguishing bacteriolytic from bacteriostatic activity of an antibiotic agent. J Microbiol Methods 40:199-206
-
(2000)
J Microbiol Methods
, vol.40
, pp. 199-206
-
-
Mardones, G.1
Venegas, A.2
-
42
-
-
36549089069
-
Differential assay for high-throughput screening of antibacterial compounds
-
Falk SP, Ulijasz AT, Weisblum B (2007) Differential assay for high-throughput screening of antibacterial compounds. J Biomol Screen 12:1102-1108
-
(2007)
J Biomol Screen
, vol.12
, pp. 1102-1108
-
-
Falk, S.P.1
Ulijasz, A.T.2
Weisblum, B.3
-
43
-
-
0024246790
-
Lysobactin, a novel antibacterial agent produced by Lysobacter sp. I. Taxonomy, isolation and partial characterization
-
O'Sullivan J, McCullough JE, Tymiak AA et al (1988) Lysobactin, a novel antibacterial agent produced by Lysobacter sp. I. Taxonomy, isolation and partial characterization. J Antibiot 41:1740-1744
-
(1988)
J Antibiot
, vol.41
, pp. 1740-1744
-
-
O'Sullivan, J.1
McCullough, J.E.2
Tymiak, A.A.3
-
44
-
-
0022629180
-
Glycopeptide antibiotics: A mechanism-based screen employing a bacterial cell wall receptor mimetic
-
Rake JB, Gerber R, Mehta RJ et al (1986) Glycopeptide antibiotics: a mechanism-based screen employing a bacterial cell wall receptor mimetic. J Antibiot 39:58-67
-
(1986)
J Antibiot
, vol.39
, pp. 58-67
-
-
Rake, J.B.1
Gerber, R.2
Mehta, R.J.3
-
45
-
-
0024511992
-
A42867, a novel glycopeptide antibiotic
-
Riva E, Gastaldo L, Beretta MG et al (1989) A42867, a novel glycopeptide antibiotic. J Antibiot 42:497-505
-
(1989)
J Antibiot
, vol.42
, pp. 497-505
-
-
Riva, E.1
Gastaldo, L.2
Beretta, M.G.3
-
46
-
-
0036215198
-
Identification of compounds that inhibit late steps of peptidoglycan synthesis in bacteria
-
DeCenzo M, Kuranda M, Cohen S et al (2002) Identification of compounds that inhibit late steps of peptidoglycan synthesis in bacteria. J Antibiot 55:288-295
-
(2002)
J Antibiot
, vol.55
, pp. 288-295
-
-
Decenzo, M.1
Kuranda, M.2
Cohen, S.3
-
47
-
-
29944447456
-
Anucleate cell blue assay: A useful tool for identifying novel type II topoisomerase inhibitors
-
Oyamada Y, Ito H, Fujimoto-Nakamura M et al (2006) Anucleate cell blue assay: a useful tool for identifying novel type II topoisomerase inhibitors. Antimicrob Agents Chemother 50:348-350
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 348-350
-
-
Oyamada, Y.1
Ito, H.2
Fujimoto-Nakamura, M.3
-
48
-
-
13544274210
-
MreB actin-mediated segregation of a specific region of a bacterial chromosome
-
Gitai Z, Dye NA, Reisenauer A et al (2005) MreB actin-mediated segregation of a specific region of a bacterial chromosome. Cell 120:329-341
-
(2005)
Cell
, vol.120
, pp. 329-341
-
-
Gitai, Z.1
Dye, N.A.2
Reisenauer, A.3
-
49
-
-
0041701451
-
Novel S-benzylisothiourea compound that induces spherical cells in Escherichia coli probably by acting on a rod-shape-determining protein(s) other than penicillin-binding protein 2
-
Iwai N, Nagai K, Wachi M (2002) Novel S-benzylisothiourea compound that induces spherical cells in Escherichia coli probably by acting on a rod-shape-determining protein(s) other than penicillin-binding protein 2. Biosci Biotechnol Biochem 66:2658-2662
-
(2002)
Biosci Biotechnol Biochem
, vol.66
, pp. 2658-2662
-
-
Iwai, N.1
Nagai, K.2
Wachi, M.3
-
50
-
-
41049085230
-
A robust screen for novel antibiotics: Specific knockout of the initiator of bacterial DNA replication
-
Fossum S, De Pascale G, Weigel C et al (2008) A robust screen for novel antibiotics: specific knockout of the initiator of bacterial DNA replication. FEMS Microbiol Lett 281: 210-214
-
(2008)
FEMS Microbiol Lett
, vol.281
, pp. 210-214
-
-
Fossum, S.1
De Pascale, G.2
Weigel, C.3
-
51
-
-
0029586501
-
The envA permeability/cell division gene of Escherichia coli encodes the second enzyme of lipid A biosynthesis. UDP-3-O-(R-3- hydroxymyristoyl)-N-acetylglucosamine deacetylase
-
270
-
Young K, Silver LL, Bramhill D et al (270) The envA permeability/cell division gene of Escherichia coli encodes the second enzyme of lipid A biosynthesis. UDP-3-O-(R-3- hydroxymyristoyl)-N-acetylglucosamine deacetylase. J Biol Chem 270:30384-30391
-
J Biol Chem
, vol.270
, pp. 30384-30391
-
-
Young, K.1
Silver, L.L.2
Bramhill, D.3
-
52
-
-
0036096165
-
Antibacterial activities and characterization of novel inhibitors of LpxC
-
Clements JM, Coignard F, Johnson I et al (2002) Antibacterial activities and characterization of novel inhibitors of LpxC. Antimicrob Agents Chemother 46:1793-1799
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 1793-1799
-
-
Clements, J.M.1
Coignard, F.2
Johnson, I.3
-
53
-
-
50249172242
-
Determination of antibiotic hypersensitivity among 4000 single gene knockout mutants of Escherichia coli
-
Tamae C, Liu A, Kim K et al (2008) Determination of antibiotic hypersensitivity among 4000 single gene knockout mutants of Escherichia coli. J Bacteriol 190:5981-5988
-
(2008)
J Bacteriol
, vol.190
, pp. 5981-5988
-
-
Tamae, C.1
Liu, A.2
Kim, K.3
-
54
-
-
66249114348
-
Characterization of the role of the Escherichia coli periplasmic chaperone SurA using differential proteomics
-
Vertommen D, Ruiz N, Leverrier P et al (2009) Characterization of the role of the Escherichia coli periplasmic chaperone SurA using differential proteomics. Proteomics 9:2432-2443
-
(2009)
Proteomics
, vol.9
, pp. 2432-2443
-
-
Vertommen, D.1
Ruiz, N.2
Leverrier, P.3
-
55
-
-
0036256037
-
An array of target-specific screening strains for antibacterial discovery
-
DeVito JA, Mills JA, Liu VG et al (2002) An array of target-specific screening strains for antibacterial discovery. Nat Biotechnol 20:478-483
-
(2002)
Nat Biotechnol
, vol.20
, pp. 478-483
-
-
Devito, J.A.1
Mills, J.A.2
Liu, V.G.3
-
56
-
-
0035929121
-
Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA
-
Ji Y, Zhang B, Van SF et al (2001) Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA. Science 293:2266-2299
-
(2001)
Science
, vol.293
, pp. 2266-2299
-
-
Ji, Y.1
Zhang, B.2
Van, S.F.3
-
57
-
-
0036271625
-
A genome-wide strategy for the identification of essential genes in Staphylococcus aureus
-
Forsyth RA, Haselbeck RJ, Ohlsen KL et al (2002) A genome-wide strategy for the identification of essential genes in Staphylococcus aureus. Mol Microbiol 43:1387-1400
-
(2002)
Mol Microbiol
, vol.43
, pp. 1387-1400
-
-
Forsyth, R.A.1
Haselbeck, R.J.2
Ohlsen, K.L.3
-
59
-
-
33748482185
-
Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy
-
Singh SB, Jayasuriya H, Ondeyka JG (2006) Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy. J Am Chem Soc 128:11916-11920
-
(2006)
J Am Chem Soc
, vol.128
, pp. 11916-11920
-
-
Singh, S.B.1
Jayasuriya, H.2
Ondeyka, J.G.3
-
60
-
-
34250649348
-
Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties
-
Wang J, Kodali S, Lee SH et al (2007) Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties. Proc Natl Acad Sci USA 104:7612-7616
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7612-7616
-
-
Wang, J.1
Kodali, S.2
Lee, S.H.3
-
61
-
-
0242693130
-
Bacterial membrane lipids: Where do we stand
-
Cronan JE (2003) Bacterial membrane lipids: where do we stand? Ann Rev Microbiol 57:203-224
-
(2003)
Ann Rev Microbiol
, vol.57
, pp. 203-224
-
-
Cronan, J.E.1
-
62
-
-
34248340854
-
Evaluation of the metS and murB loci for antibiotic discovery using targeted antisense RNA expression analysis in Bacillus anthracis
-
Kedar GC, Brown-Driver V, Reyes DR et al (2007) Evaluation of the metS and murB loci for antibiotic discovery using targeted antisense RNA expression analysis in Bacillus anthracis. Antimicrob Agents Chemother 51:1708-1718
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 1708-1718
-
-
Kedar, G.C.1
Brown-Driver, V.2
Reyes, D.R.3
-
63
-
-
44449179238
-
Comparison of the essential cellular functions of the two murA genes of Bacillus anthracis
-
Kedar GC, Brown-Driver V, Reyes DR et al (2008) Comparison of the essential cellular functions of the two murA genes of Bacillus anthracis. Antimicrob Agents Chemother 52: 2009-2013
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 2009-2013
-
-
Kedar, G.C.1
Brown-Driver, V.2
Reyes, D.R.3
-
64
-
-
69049093794
-
A Staphylococcus aureus fitness test platform for mechanism-based profiling of antibacterial compounds
-
Donald RG, Skwish S, Forsyth RA et al (2009) A Staphylococcus aureus fitness test platform for mechanism-based profiling of antibacterial compounds. Chem Biol 16:826-836
-
(2009)
Chem Biol
, vol.16
, pp. 826-836
-
-
Donald, R.G.1
Skwish, S.2
Forsyth, R.A.3
-
65
-
-
0033214149
-
Genome-wide expression profiling in Escherichia coli K-12
-
Richmond CS, Glasner JD, Mau R et al (1999) Genome-wide expression profiling in Escherichia coli K-12. Nucleic Acids Res 27:3821-3835
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 3821-3835
-
-
Richmond, C.S.1
Glasner, J.D.2
Mau, R.3
-
66
-
-
0035154372
-
Gene expression changes triggered by exposure of Haemophilus influenzae to novobiocin or ciprofloxacin: Combined transcription and translation analysis
-
Gmuender H, Kuratli K, Di Padova K et al (2001) Gene expression changes triggered by exposure of Haemophilus influenzae to novobiocin or ciprofloxacin: combined transcription and translation analysis. Genome Res 11:28-42
-
(2001)
Genome Res
, vol.11
, pp. 28-42
-
-
Gmuender, H.1
Kuratli, K.2
Di Padova, K.3
-
67
-
-
0141925858
-
Interfering with different steps of protein synthesis explored by transcriptional profiling of Escherichia coli K-12
-
Sabina J, Dover N, Templeton LJ et al (2003) Interfering with different steps of protein synthesis explored by transcriptional profiling of Escherichia coli K-12. J Bacteriol 185:6158-6170
-
(2003)
J Bacteriol
, vol.185
, pp. 6158-6170
-
-
Sabina, J.1
Dover, N.2
Templeton, L.J.3
-
68
-
-
0042697666
-
Comparison of the changes in global gene expression of Escherichia coli induced by four bactericidal agents
-
Shaw KJ, Miller N, Liu X et al (2003) Comparison of the changes in global gene expression of Escherichia coli induced by four bactericidal agents. J Mol Microbiol Biotechnol 5:105-122
-
(2003)
J Mol Microbiol Biotechnol
, vol.5
, pp. 105-122
-
-
Shaw, K.J.1
Miller, N.2
Liu, X.3
-
69
-
-
12944327876
-
Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants
-
Frieberg C, Fischer HP, Brunner NA (2005) Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants. Antimicrob Agents Chemother 49:749-759
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 749-759
-
-
Frieberg, C.1
Fischer, H.P.2
Brunner, N.A.3
-
70
-
-
0347766000
-
Identification of antibiotic stress-inducible promoters: A systematic approach to novel pathway-specific reporter assays for antibacterial drug discovery
-
Fischer HP, Brunner NA, Wieland B et al (2004) Identification of antibiotic stress-inducible promoters: a systematic approach to novel pathway-specific reporter assays for antibacterial drug discovery. Genome Res 14:90-98
-
(2004)
Genome Res
, vol.14
, pp. 90-98
-
-
Fischer, H.P.1
Brunner, N.A.2
Wieland, B.3
-
71
-
-
33846125002
-
Applications of whole-cell bacterial sensors in biotechnology and environmental science
-
Yagi K (2007) Applications of whole-cell bacterial sensors in biotechnology and environmental science. Appl Microbiol Biotechnol 73:1251-1258
-
(2007)
Appl Microbiol Biotechnol
, vol.73
, pp. 1251-1258
-
-
Yagi, K.1
-
72
-
-
0037168560
-
Transcriptional modulation of bacterial gene expression by subinhibitory concentrations of antibiotics
-
Goh EB, Yim G, Tsui W et al (2002) Transcriptional modulation of bacterial gene expression by subinhibitory concentrations of antibiotics. Proc Natl Acad Sci USA 99:17025-17030
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 17025-17030
-
-
Goh, E.B.1
Yim, G.2
Tsui, W.3
-
73
-
-
35748937348
-
Stress-activated bioluminescent Escherichia coli sensors for antimicrobial agents detection
-
Shapiro E, Baneyx F (2007) Stress-activated bioluminescent Escherichia coli sensors for antimicrobial agents detection. J Biotechnol 132:487-493
-
(2007)
J Biotechnol
, vol.132
, pp. 487-493
-
-
Shapiro, E.1
Baneyx, F.2
-
74
-
-
0032702687
-
Stress responses as a tool to detect and characterize the mode of action of antibacterial agents
-
Bianchi A, Baneyx F (1999) Stress responses as a tool to detect and characterize the mode of action of antibacterial agents. Appl Environ Microbiol 65:5023-5027
-
(1999)
Appl Environ Microbiol
, vol.65
, pp. 5023-5027
-
-
Bianchi, A.1
Baneyx, F.2
-
75
-
-
0034666679
-
Detection and quantification of tetracyclines by whole cell biosensors
-
Hansen LH, Sörensen SJ (2000) Detection and quantification of tetracyclines by whole cell biosensors. FEMS Microbiol Lett 190:273-278
-
(2000)
FEMS Microbiol Lett
, vol.190
, pp. 273-278
-
-
Hansen, L.H.1
Sörensen, S.J.2
-
76
-
-
3042621796
-
Panel of Bacillus subtilis reporter strains indicative of various modes of action
-
Hutter B, Fischer C, Jacobi A et al (2004) Panel of Bacillus subtilis reporter strains indicative of various modes of action. Antimicrob Agents Chemother 48:2588-2594
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 2588-2594
-
-
Hutter, B.1
Fischer, C.2
Jacobi, A.3
-
77
-
-
35448931532
-
Novel whole-cell antibiotic biosensors for compound discovery
-
Urban A, Eckermann S, Fast B et al (2007) Novel whole-cell antibiotic biosensors for compound discovery. Appl Environ Microbiol 73:6436-6443
-
(2007)
Appl Environ Microbiol
, vol.73
, pp. 6436-6443
-
-
Urban, A.1
Eckermann, S.2
Fast, B.3
-
78
-
-
3342969325
-
Prediction of mechanisms of action of antibacterial compounds by gene expression profiling
-
Hutter B, Schaab C, Albrecht S et al (2004) Prediction of mechanisms of action of antibacterial compounds by gene expression profiling. Antimicrob Agents Chemother 48:2838-2844
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 2838-2844
-
-
Hutter, B.1
Schaab, C.2
Albrecht, S.3
-
79
-
-
0035991865
-
Stress-based identification and classification of antibacterial agents: Second-generation Escherichia coli reporter strains and optimization of detection
-
Shapiro E, Baneyx F (2002) Stress-based identification and classification of antibacterial agents: second-generation Escherichia coli reporter strains and optimization of detection. Antimicrob Agents Chemother 46:2490-2497
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 2490-2497
-
-
Shapiro, E.1
Baneyx, F.2
-
80
-
-
27944432167
-
A set of multicolored Photinus pyralis luciferase mutants for in vivo bioluminescence applications
-
Shapiro E, Lu C, Baneyx F (2005) A set of multicolored Photinus pyralis luciferase mutants for in vivo bioluminescence applications. Protein Eng Des Sel 18:581-587
-
(2005)
Protein Eng des Sel
, vol.18
, pp. 581-587
-
-
Shapiro, E.1
Lu, C.2
Baneyx, F.3
-
81
-
-
3042670809
-
Molecular characterization of benzimidazole resistance in Helicobacter pylori
-
Mills SD, Yang W, MacCormack K (2004) Molecular characterization of benzimidazole resistance in Helicobacter pylori. Antimicrob Agents Chemother 48:2524-2530
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 2524-2530
-
-
Mills, S.D.1
Yang, W.2
Maccormack, K.3
-
82
-
-
27144460621
-
Dysregulation of bacterial proteolytic machinery by a new class of antibiotics
-
Brötz-Oesterhelt H, Beyer D, Kroll H-P et al (2005) Dysregulation of bacterial proteolytic machinery by a new class of antibiotics. Nat Med 11:1082-1087
-
(2005)
Nat Med
, vol.11
, pp. 1082-1087
-
-
Brötz-Oesterhelt, H.1
Beyer, D.2
Kroll, H.-P.3
-
83
-
-
0035991851
-
PCR-based ordered genomic libraries: A new approach to drug target identification for Streptococcus pneumoniae
-
Belanger AE, Lai A, Brackman MA et al (2002) PCR-based ordered genomic libraries: a new approach to drug target identification for Streptococcus pneumoniae. Antimicrob Agents Chemother 46:2507-2512
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 2507-2512
-
-
Belanger, A.E.1
Lai, A.2
Brackman, M.A.3
-
84
-
-
5444276383
-
Multicopy suppressors for novel antibacterial compounds reveal targets and drug efflux susceptibility
-
Li X, Zolli-Juran M, Cechetto JD, Daigle DM et al (2004) Multicopy suppressors for novel antibacterial compounds reveal targets and drug efflux susceptibility. Chem Biol 11: 1423-1430
-
(2004)
Chem Biol
, vol.11
, pp. 1423-1430
-
-
Li, X.1
Zolli-Juran, M.2
Cechetto, J.D.3
Daigle, D.M.4
-
85
-
-
48749117988
-
Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors
-
Miller AA, Bundy GL, Mott JE et al (2008) Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. Antimicrob Agents Chemother 52:2806-2812
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 2806-2812
-
-
Miller, A.A.1
Bundy, G.L.2
Mott, J.E.3
|