-
1
-
-
72049130805
-
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
-
Jack CR, Knopman DS, Jagust WJ, Shaw LM, Aisen PS, Weiner MW, et al. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol. 2010;9:119-28.
-
(2010)
Lancet Neurol
, vol.9
, pp. 119-128
-
-
Jack, C.R.1
Knopman, D.S.2
Jagust, W.J.3
Shaw, L.M.4
Aisen, P.S.5
Weiner, M.W.6
-
2
-
-
84865529158
-
Clinical and biomarker changes in dominantly inherited Alzheimer's disease
-
Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med. 2012;367:795-804.
-
(2012)
N Engl J Med
, vol.367
, pp. 795-804
-
-
Bateman, R.J.1
Xiong, C.2
Benzinger, T.L.3
Fagan, A.M.4
Goate, A.5
Fox, N.C.6
-
3
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
-
Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 2002;297:353-6.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
4
-
-
84872379077
-
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
-
Jack Jr CR, Knopman DS, Jagust WJ, Petersen RC, Weiner MW, Aisen PS, et al. Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol. 2013;12:207-16.
-
(2013)
Lancet Neurol
, vol.12
, pp. 207-216
-
-
Jack, C.R.1
Knopman, D.S.2
Jagust, W.J.3
Petersen, R.C.4
Weiner, M.W.5
Aisen, P.S.6
-
5
-
-
0019993831
-
Immunoglobulins and complement factors in senile plaques-an immunoperoxidase study
-
Eikelenboom P, Stam FC. Immunoglobulins and complement factors in senile plaques-an immunoperoxidase study. Acta Neuropathol. 1982;57:239-42.
-
(1982)
Acta Neuropathol
, vol.57
, pp. 239-242
-
-
Eikelenboom, P.1
Stam, F.C.2
-
7
-
-
75149118999
-
Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy
-
McGeer EG, McGeer PL. Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy. J Alzheimers Dis. 2010;19:355-61.
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 355-361
-
-
McGeer, E.G.1
McGeer, P.L.2
-
8
-
-
77954977618
-
Neuroinflammation in Alzheimer's disease: mechanisms, pathologic consequences, and potential for therapeutic manipulation
-
Hensley K. Neuroinflammation in Alzheimer's disease: mechanisms, pathologic consequences, and potential for therapeutic manipulation. J Alzheimers Dis. 2010;21:1-14.
-
(2010)
J Alzheimers Dis
, vol.21
, pp. 1-14
-
-
Hensley, K.1
-
9
-
-
84885456046
-
The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy
-
McGeer PL, McGeer EG. The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy. Acta Neuropathol. 2013;126:479-97.
-
(2013)
Acta Neuropathol
, vol.126
, pp. 479-497
-
-
McGeer, P.L.1
McGeer, E.G.2
-
11
-
-
0030250615
-
beta-Amyloid converts an acute phase injury response to chronic injury responses
-
Cotman CW, Tenner AJ, Cummings BJ. beta-Amyloid converts an acute phase injury response to chronic injury responses. Neurobiol Aging. 1996;17:723-31.
-
(1996)
Neurobiol Aging
, vol.17
, pp. 723-731
-
-
Cotman, C.W.1
Tenner, A.J.2
Cummings, B.J.3
-
13
-
-
55049142500
-
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE
-
Bertram L, Lange C, Mullin K, Parkinson M, Hsiao M, Hogan MF, et al. Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am J Hum Genet. 2008;83:623-32.
-
(2008)
Am J Hum Genet
, vol.83
, pp. 623-632
-
-
Bertram, L.1
Lange, C.2
Mullin, K.3
Parkinson, M.4
Hsiao, M.5
Hogan, M.F.6
-
14
-
-
70349558522
-
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
-
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet. 2009;41:1088-93.
-
(2009)
Nat Genet
, vol.41
, pp. 1088-1093
-
-
Harold, D.1
Abraham, R.2
Hollingworth, P.3
Sims, R.4
Gerrish, A.5
Hamshere, M.L.6
-
15
-
-
84872057940
-
TREM2 variants in Alzheimer's disease
-
Guerreiro R, Wojtas A, Bras J, Carrasquillo M, Rogaeva E, Majounie E, et al. TREM2 variants in Alzheimer's disease. N Engl J Med. 2013;368:117-27.
-
(2013)
N Engl J Med
, vol.368
, pp. 117-127
-
-
Guerreiro, R.1
Wojtas, A.2
Bras, J.3
Carrasquillo, M.4
Rogaeva, E.5
Majounie, E.6
-
16
-
-
84888317489
-
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
-
European Alzheimer's Disease I, Genetic, Environmental Risk in Alzheimer's D, Alzheimer's Disease Genetic C, Cohorts for H, Aging Research in Genomic E. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet. 2013;45:1452-8.
-
(2013)
Nat Genet
, vol.45
, pp. 1452-1458
-
-
-
17
-
-
78549264026
-
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
-
Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet. 2009;41:1094-9.
-
(2009)
Nat Genet
, vol.41
, pp. 1094-1099
-
-
Lambert, J.C.1
Heath, S.2
Even, G.3
Campion, D.4
Sleegers, K.5
Hiltunen, M.6
-
18
-
-
78751635081
-
Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort
-
Kim S, Swaminathan S, Shen L, Risacher SL, Nho K, Foroud T, et al. Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort. Neurology. 2011;76:69-79.
-
(2011)
Neurology
, vol.76
, pp. 69-79
-
-
Kim, S.1
Swaminathan, S.2
Shen, L.3
Risacher, S.L.4
Nho, K.5
Foroud, T.6
-
19
-
-
84894517016
-
APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study
-
Ramanan VK, Risacher SL, Nho K, Kim S, Swaminathan S, Shen L, et al. APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study. Mol Psychiatry. 2013;19(3):351-7.
-
(2013)
Mol Psychiatry
, vol.19
, Issue.3
, pp. 351-357
-
-
Ramanan, V.K.1
Risacher, S.L.2
Nho, K.3
Kim, S.4
Swaminathan, S.5
Shen, L.6
-
20
-
-
0019867064
-
Biological models and statistical interactions-an example from multistage carcinogenesis
-
Siemiatycki J, Thomas DC. Biological models and statistical interactions-an example from multistage carcinogenesis. Int J Epidemiol. 1981;10:383-7.
-
(1981)
Int J Epidemiol
, vol.10
, pp. 383-387
-
-
Siemiatycki, J.1
Thomas, D.C.2
-
21
-
-
0036797562
-
Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans
-
Cordell HJ. Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans. Hum Mol Genet. 2002;11:2463-8.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2463-2468
-
-
Cordell, H.J.1
-
22
-
-
84908162497
-
Detecting epistasis in human complex traits
-
Wei WH, Hemani G, Haley CS. Detecting epistasis in human complex traits. Nat Rev Genet. 2014;15:722-33.
-
(2014)
Nat Rev Genet
, vol.15
, pp. 722-733
-
-
Wei, W.H.1
Hemani, G.2
Haley, C.S.3
-
23
-
-
84894094478
-
Epistatic genetic effects among Alzheimer's candidate genes
-
Hohman TJ, Koran ME, Thornton-Wells T, Initiativ AsN. Epistatic genetic effects among Alzheimer's candidate genes. Plos One. 2013;8(11):e80839.
-
(2013)
Plos One
, vol.8
, Issue.11
, pp. e80839
-
-
Hohman, T.J.1
Koran, M.E.2
Thornton-Wells, T.3
-
24
-
-
84868153789
-
Dissociation between brain amyloid deposition and metabolism in early mild cognitive impairment
-
Wu LY, Rowley J, Mohades S, Leuzy A, Dauar MT, Shin M, et al. Dissociation between brain amyloid deposition and metabolism in early mild cognitive impairment. Plos One. 2012;7(10):e47905.
-
(2012)
Plos One
, vol.7
, Issue.10
, pp. e47905
-
-
Wu, L.Y.1
Rowley, J.2
Mohades, S.3
Leuzy, A.4
Dauar, M.T.5
Shin, M.6
-
25
-
-
0030817147
-
Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease
-
Webster S, Lue LF, Brachova L, Tenner AJ, McGeer PL, Terai K, et al. Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease. Neurobiol Aging. 1997;18:415-21.
-
(1997)
Neurobiol Aging
, vol.18
, pp. 415-421
-
-
Webster, S.1
Lue, L.F.2
Brachova, L.3
Tenner, A.J.4
McGeer, P.L.5
Terai, K.6
-
26
-
-
0034612175
-
Inflammation and Alzheimer's disease
-
Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, et al. Inflammation and Alzheimer's disease. Neurobiol Aging. 2000;21:383-421.
-
(2000)
Neurobiol Aging
, vol.21
, pp. 383-421
-
-
Akiyama, H.1
Barger, S.2
Barnum, S.3
Bradt, B.4
Bauer, J.5
Cole, G.M.6
-
27
-
-
33947727192
-
Interleukins, inflammation, and mechanisms of Alzheimer's disease
-
Weisman D, Hakimian E, Ho GJ. Interleukins, inflammation, and mechanisms of Alzheimer's disease. Vitam Horm. 2006;74:505-30.
-
(2006)
Vitam Horm
, vol.74
, pp. 505-530
-
-
Weisman, D.1
Hakimian, E.2
Ho, G.J.3
-
28
-
-
78049419440
-
A meta-analysis of cytokines in Alzheimer's disease
-
Swardfager W, Lanctot K, Rothenburg L, Wong A, Cappell J, Herrmann N. A meta-analysis of cytokines in Alzheimer's disease. Biol Psychiatry. 2010;68:930-41.
-
(2010)
Biol Psychiatry
, vol.68
, pp. 930-941
-
-
Swardfager, W.1
Lanctot, K.2
Rothenburg, L.3
Wong, A.4
Cappell, J.5
Herrmann, N.6
-
29
-
-
79959669857
-
Expression profiles of cytokines in the brains of Alzheimer's disease (AD) patients compared to the brains of non-demented patients with and without increasing AD pathology
-
Morimoto K, Horio J, Satoh H, Sue L, Beach T, Arita S, et al. Expression profiles of cytokines in the brains of Alzheimer's disease (AD) patients compared to the brains of non-demented patients with and without increasing AD pathology. J Alzheimers Dis. 2011;25:59-76.
-
(2011)
J Alzheimers Dis
, vol.25
, pp. 59-76
-
-
Morimoto, K.1
Horio, J.2
Satoh, H.3
Sue, L.4
Beach, T.5
Arita, S.6
-
30
-
-
84861078831
-
A review: inflammatory process in Alzheimer's disease, role of cytokines
-
Rubio-Perez JM, Morillas-Ruiz JM. A review: inflammatory process in Alzheimer's disease, role of cytokines. ScientificWorldJournal. 2012;2012:756357.
-
(2012)
ScientificWorldJournal
, vol.2012
, pp. 756357
-
-
Rubio-Perez, J.M.1
Morillas-Ruiz, J.M.2
-
31
-
-
18244413523
-
Decreased soluble interleukin-6 receptor in cerebrospinal fluid of patients with Alzheimer's disease
-
Hampel H, Sunderland T, Kotter HU, Schneider C, Teipel SJ, Padberg F, et al. Decreased soluble interleukin-6 receptor in cerebrospinal fluid of patients with Alzheimer's disease. Brain Res. 1998;780:356-9.
-
(1998)
Brain Res
, vol.780
, pp. 356-359
-
-
Hampel, H.1
Sunderland, T.2
Kotter, H.U.3
Schneider, C.4
Teipel, S.J.5
Padberg, F.6
-
32
-
-
0345130090
-
Interleukin-6 and the soluble IL-6 receptor are decreased in cerebrospinal fluid of geriatric patients with major depression: no alteration of soluble gp130
-
Stubner S, Schon T, Padberg F, Teipel SJ, Schwarz MJ, Haslinger A, et al. Interleukin-6 and the soluble IL-6 receptor are decreased in cerebrospinal fluid of geriatric patients with major depression: no alteration of soluble gp130. Neurosci Lett. 1999;259:145-8.
-
(1999)
Neurosci Lett
, vol.259
, pp. 145-148
-
-
Stubner, S.1
Schon, T.2
Padberg, F.3
Teipel, S.J.4
Schwarz, M.J.5
Haslinger, A.6
-
33
-
-
35448979876
-
Altered plasma cytokine levels in Alzheimer's disease: correlation with the disease progression
-
Motta M, Imbesi R, Di Rosa M, Stivala F, Malaguarnera L. Altered plasma cytokine levels in Alzheimer's disease: correlation with the disease progression. Immunol Lett. 2007;114:46-51.
-
(2007)
Immunol Lett
, vol.114
, pp. 46-51
-
-
Motta, M.1
Imbesi, R.2
Rosa, M.3
Stivala, F.4
Malaguarnera, L.5
-
34
-
-
42649084052
-
The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective
-
Shaftel SS, Griffin WS, O'Banion MK. The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective. J Neuroinflammation. 2008;5:7.
-
(2008)
J Neuroinflammation
, vol.5
, pp. 7
-
-
Shaftel, S.S.1
Griffin, W.S.2
O'Banion, M.K.3
-
35
-
-
84870932482
-
Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline
-
Vom Berg J, Prokop S, Miller KR, Obst J, Kalin RE, Lopategui-Cabezas I, et al. Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline. Nat Med. 2012;18:1812-9.
-
(2012)
Nat Med
, vol.18
, pp. 1812-1819
-
-
Vom Berg, J.1
Prokop, S.2
Miller, K.R.3
Obst, J.4
Kalin, R.E.5
Lopategui-Cabezas, I.6
-
37
-
-
68449089420
-
Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease
-
Potkin SG, Guffanti G, Lakatos A, Turner JA, Kruggel F, Fallon JH, et al. Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease. Plos One. 2009;4(8):e6501.
-
(2009)
Plos One
, vol.4
, Issue.8
, pp. e6501
-
-
Potkin, S.G.1
Guffanti, G.2
Lakatos, A.3
Turner, J.A.4
Kruggel, F.5
Fallon, J.H.6
-
38
-
-
34548292504
-
PLINK: a tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, Bender D, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007;81:559-75.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.R.5
Bender, D.6
-
39
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet. 2006;38:904-9.
-
(2006)
Nat Genet
, vol.38
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
41
-
-
57249114505
-
SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap
-
Johnson AD, Handsaker RE, Pulit SL, Nizzari MM, O'Donnell CJ, de Bakker PIW. SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics. 2008;24:2938-9.
-
(2008)
Bioinformatics
, vol.24
, pp. 2938-2939
-
-
Johnson, A.D.1
Handsaker, R.E.2
Pulit, S.L.3
Nizzari, M.M.4
O'Donnell, C.J.5
Bakker, P.I.W.6
-
42
-
-
84949030594
-
-
Vienna, Austria: R Foundation for Statistical Computing
-
Team RDC. R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2014. ISBN 3-900051-07-0.
-
(2014)
-
-
-
43
-
-
65249159879
-
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
-
Shaw LM, Vanderstichele H, Knapik-Czajka M, Clark CM, Aisen PS, Petersen RC, et al. Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects. Ann Neurol. 2009;65:403-13.
-
(2009)
Ann Neurol
, vol.65
, pp. 403-413
-
-
Shaw, L.M.1
Vanderstichele, H.2
Knapik-Czajka, M.3
Clark, C.M.4
Aisen, P.S.5
Petersen, R.C.6
-
44
-
-
79958102380
-
Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI
-
Shaw LM, Vanderstichele H, Knapik-Czajka M, Figurski M, Coart E, Blennow K, et al. Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI. Acta Neuropathol. 2011;121:597-609.
-
(2011)
Acta Neuropathol
, vol.121
, pp. 597-609
-
-
Shaw, L.M.1
Vanderstichele, H.2
Knapik-Czajka, M.3
Figurski, M.4
Coart, E.5
Blennow, K.6
-
45
-
-
33746587338
-
Developments in random field theory
-
Worsley KJ. Developments in random field theory. In: Human brain function volume 2. 2003. p. 881-86.
-
(2003)
Human brain function
, vol.2
, pp. 881-886
-
-
Worsley, K.J.1
-
46
-
-
84907992094
-
Macular pigment, visual function, and macular disease among subjects with Alzheimer's disease: an exploratory study
-
Nolan JM, Loskutova E, Howard AN, Moran R, Mulcahy R, Stack J, et al. Macular pigment, visual function, and macular disease among subjects with Alzheimer's disease: an exploratory study. J Alzheimers Dis. 2014;42(4):1191-202.
-
(2014)
J Alzheimers Dis
, vol.42
, Issue.4
, pp. 1191-1202
-
-
Nolan, J.M.1
Loskutova, E.2
Howard, A.N.3
Moran, R.4
Mulcahy, R.5
Stack, J.6
-
47
-
-
84887080613
-
Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration
-
Seddon JM, Yu Y, Miller EC, Reynolds R, Tan PL, Gowrisankar S, et al. Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration. Nat Genet. 2013;45:1366-70.
-
(2013)
Nat Genet
, vol.45
, pp. 1366-1370
-
-
Seddon, J.M.1
Yu, Y.2
Miller, E.C.3
Reynolds, R.4
Tan, P.L.5
Gowrisankar, S.6
-
48
-
-
0032479929
-
Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide
-
Bradt BM, Kolb WP, Cooper NR. Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide. J Exp Med. 1998;188:431-8.
-
(1998)
J Exp Med
, vol.188
, pp. 431-438
-
-
Bradt, B.M.1
Kolb, W.P.2
Cooper, N.R.3
-
49
-
-
4944258716
-
The role of inflammation in Alzheimer's disease
-
Tuppo EE, Arias HR. The role of inflammation in Alzheimer's disease. Int J Biochem Cell Biol. 2005;37:289-305.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 289-305
-
-
Tuppo, E.E.1
Arias, H.R.2
-
51
-
-
0026447529
-
Complement activation by beta-amyloid in Alzheimer disease
-
Rogers J, Cooper NR, Webster S, Schultz J, McGeer PL, Styren SD, et al. Complement activation by beta-amyloid in Alzheimer disease. Proc Natl Acad Sci U S A. 1992;89:10016-20.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 10016-10020
-
-
Rogers, J.1
Cooper, N.R.2
Webster, S.3
Schultz, J.4
McGeer, P.L.5
Styren, S.D.6
-
52
-
-
0028217539
-
Ultrastructural localization of complement membrane attack complex (MAC)-like immunoreactivity in brains of patients with Alzheimer's disease
-
Itagaki S, Akiyama H, Saito H, McGeer PL. Ultrastructural localization of complement membrane attack complex (MAC)-like immunoreactivity in brains of patients with Alzheimer's disease. Brain Res. 1994;645:78-84.
-
(1994)
Brain Res
, vol.645
, pp. 78-84
-
-
Itagaki, S.1
Akiyama, H.2
Saito, H.3
McGeer, P.L.4
-
53
-
-
0027164921
-
Clusterin, the human apolipoprotein and complement inhibitor, binds to complement C7, C8 beta, and the b domain of C9
-
Tschopp J, Chonn A, Hertig S, French LE. Clusterin, the human apolipoprotein and complement inhibitor, binds to complement C7, C8 beta, and the b domain of C9. J Immunol. 1993;151:2159-65.
-
(1993)
J Immunol
, vol.151
, pp. 2159-2165
-
-
Tschopp, J.1
Chonn, A.2
Hertig, S.3
French, L.E.4
-
55
-
-
14044259453
-
Molecular screening and association analyses of the interleukin 6 receptor gene variants with type 2 diabetes, diabetic nephropathy, and insulin sensitivity
-
Wang H, Zhang Z, Chu W, Hale T, Cooper JJ, Elbein SC. Molecular screening and association analyses of the interleukin 6 receptor gene variants with type 2 diabetes, diabetic nephropathy, and insulin sensitivity. J Clin Endocrinol Metab. 2005;90:1123-9.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 1123-1129
-
-
Wang, H.1
Zhang, Z.2
Chu, W.3
Hale, T.4
Cooper, J.J.5
Elbein, S.C.6
-
56
-
-
84897886749
-
Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease
-
Ferreira ST, Clarke JR, Bomfim TR, De Felice FG. Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease. Alzheimers Dement. 2014;10:S76-83.
-
(2014)
Alzheimers Dement
, vol.10
, pp. S76-83
-
-
Ferreira, S.T.1
Clarke, J.R.2
Bomfim, T.R.3
Felice, F.G.4
-
57
-
-
64449084857
-
Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults
-
Walston JD, Matteini AM, Nievergelt C, Lange LA, Fallin DM, Barzilai N, et al. Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults. Exp Gerontol. 2009;44:350-5.
-
(2009)
Exp Gerontol
, vol.44
, pp. 350-355
-
-
Walston, J.D.1
Matteini, A.M.2
Nievergelt, C.3
Lange, L.A.4
Fallin, D.M.5
Barzilai, N.6
-
58
-
-
0027433102
-
Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6
-
Campbell IL, Abraham CR, Masliah E, Kemper P, Inglis JD, Oldstone MB, et al. Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6. Proc Natl Acad Sci U S A. 1993;90:10061-5.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 10061-10065
-
-
Campbell, I.L.1
Abraham, C.R.2
Masliah, E.3
Kemper, P.4
Inglis, J.D.5
Oldstone, M.B.6
-
59
-
-
0345104338
-
Role of interleukin-6 and soluble IL-6 receptor in region-specific induction of astrocytic differentiation and neurotrophin expression
-
Marz P, Heese K, Dimitriades-Schmutz B, Rose-John S, Otten U. Role of interleukin-6 and soluble IL-6 receptor in region-specific induction of astrocytic differentiation and neurotrophin expression. Glia. 1999;26:191-200.
-
(1999)
Glia
, vol.26
, pp. 191-200
-
-
Marz, P.1
Heese, K.2
Dimitriades-Schmutz, B.3
Rose-John, S.4
Otten, U.5
-
60
-
-
84869857934
-
Interleukin-6, a major cytokine in the central nervous system
-
Erta M, Quintana A, Hidalgo J. Interleukin-6, a major cytokine in the central nervous system. Int J Biol Sci. 2012;8:1254-66.
-
(2012)
Int J Biol Sci
, vol.8
, pp. 1254-1266
-
-
Erta, M.1
Quintana, A.2
Hidalgo, J.3
-
61
-
-
0024393839
-
Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130
-
Taga T, Hibi M, Hirata Y, Yamasaki K, Yasukawa K, Matsuda T, et al. Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130. Cell. 1989;58:573-81.
-
(1989)
Cell
, vol.58
, pp. 573-581
-
-
Taga, T.1
Hibi, M.2
Hirata, Y.3
Yamasaki, K.4
Yasukawa, K.5
Matsuda, T.6
-
62
-
-
0025010583
-
Purification and characterization of soluble human IL-6 receptor expressed in CHO cells
-
Yasukawa K, Saito T, Fukunaga T, Sekimori Y, Koishihara Y, Fukui H, et al. Purification and characterization of soluble human IL-6 receptor expressed in CHO cells. J Biochem. 1990;108:673-6.
-
(1990)
J Biochem
, vol.108
, pp. 673-676
-
-
Yasukawa, K.1
Saito, T.2
Fukunaga, T.3
Sekimori, Y.4
Koishihara, Y.5
Fukui, H.6
-
63
-
-
0029051259
-
Interleukin-6 is present in early stages of plaque formation and is restricted to the brains of Alzheimer's disease patients
-
Huell M, Strauss S, Volk B, Berger M, Bauer J. Interleukin-6 is present in early stages of plaque formation and is restricted to the brains of Alzheimer's disease patients. Acta Neuropathol. 1995;89:544-51.
-
(1995)
Acta Neuropathol
, vol.89
, pp. 544-551
-
-
Huell, M.1
Strauss, S.2
Volk, B.3
Berger, M.4
Bauer, J.5
-
64
-
-
0026553710
-
Detection of interleukin-6 and alpha 2-macroglobulin immunoreactivity in cortex and hippocampus of Alzheimer's disease patients
-
Strauss S, Bauer J, Ganter U, Jonas U, Berger M, Volk B. Detection of interleukin-6 and alpha 2-macroglobulin immunoreactivity in cortex and hippocampus of Alzheimer's disease patients. Lab Invest. 1992;66:223-30.
-
(1992)
Lab Invest
, vol.66
, pp. 223-230
-
-
Strauss, S.1
Bauer, J.2
Ganter, U.3
Jonas, U.4
Berger, M.5
Volk, B.6
-
65
-
-
0026744420
-
The participation of interleukin-6 in the pathogenesis of Alzheimer's disease
-
Bauer J, Ganter U, Strauss S, Stadtmuller G, Frommberger U, Bauer H, et al. The participation of interleukin-6 in the pathogenesis of Alzheimer's disease. Res Immunol. 1992;143:650-7.
-
(1992)
Res Immunol
, vol.143
, pp. 650-657
-
-
Bauer, J.1
Ganter, U.2
Strauss, S.3
Stadtmuller, G.4
Frommberger, U.5
Bauer, H.6
-
66
-
-
0029417080
-
Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients
-
Blum-Degen D, Muller T, Kuhn W, Gerlach M, Przuntek H, Riederer P. Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients. Neurosci Lett. 1995;202:17-20.
-
(1995)
Neurosci Lett
, vol.202
, pp. 17-20
-
-
Blum-Degen, D.1
Muller, T.2
Kuhn, W.3
Gerlach, M.4
Przuntek, H.5
Riederer, P.6
-
67
-
-
0032513251
-
Serum interleukin-6 and interleukin-6 soluble receptor in Alzheimer's disease
-
Angelis P, Scharf S, Mander A, Vajda F, Christophidis N. Serum interleukin-6 and interleukin-6 soluble receptor in Alzheimer's disease. Neurosci Lett. 1998;244:106-8.
-
(1998)
Neurosci Lett
, vol.244
, pp. 106-108
-
-
Angelis, P.1
Scharf, S.2
Mander, A.3
Vajda, F.4
Christophidis, N.5
-
68
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak HaB E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 1991;82:20.
-
(1991)
Acta Neuropathol
, vol.82
, pp. 20
-
-
Braak HaB, E.1
-
69
-
-
84903809020
-
Tracking neuroinflammation in Alzheimer's disease: the role of positron emission tomography imaging
-
Zimmer ER, Leuzy A, Benedet AL, Breitner J, Gauthier S, Rosa-Neto P. Tracking neuroinflammation in Alzheimer's disease: the role of positron emission tomography imaging. J Neuroinflammation. 2014;11:120.
-
(2014)
J Neuroinflammation
, vol.11
, pp. 120
-
-
Zimmer, E.R.1
Leuzy, A.2
Benedet, A.L.3
Breitner, J.4
Gauthier, S.5
Rosa-Neto, P.6
-
70
-
-
62449262536
-
Cerebrospinal fluid β-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain
-
Tapiola T, Alafuzoff I, Herukka S, et al. Cerebrospinal fluid β-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain. Arch Neurol. 2009;66:382-9.
-
(2009)
Arch Neurol
, vol.66
, pp. 382-389
-
-
Tapiola, T.1
Alafuzoff, I.2
Herukka, S.3
-
71
-
-
0034987322
-
Induction of complement C9 messenger RNAs in human neuronal cells by inflammatory stimuli: relevance to neurodegenerative disorders
-
Klegeris A, Schwab C, Bissonnette CJ, McGeer PL. Induction of complement C9 messenger RNAs in human neuronal cells by inflammatory stimuli: relevance to neurodegenerative disorders. Exp Gerontol. 2001;36:1179-88.
-
(2001)
Exp Gerontol
, vol.36
, pp. 1179-1188
-
-
Klegeris, A.1
Schwab, C.2
Bissonnette, C.J.3
McGeer, P.L.4
-
72
-
-
0032569682
-
Expression of complement C4 and C9 genes by human astrocytes
-
Walker DG, Kim SU, McGeer PL. Expression of complement C4 and C9 genes by human astrocytes. Brain Res. 1998;809:31-8.
-
(1998)
Brain Res
, vol.809
, pp. 31-38
-
-
Walker, D.G.1
Kim, S.U.2
McGeer, P.L.3
-
73
-
-
77649314191
-
D Phil, et al
-
JC Morris, CM Roe, C Xiong, AM Fagan, AM Goate, D Phil, et al. APOE predicts Aβ but not tau Alzheimer's pathology in cognitively normal aging Ann Neurol. 2010;67(1):122-31.
-
(2010)
APOE predicts Aβ but not tau Alzheimer's pathology in cognitively normal aging Ann Neurol
, vol.67
, Issue.1
, pp. 122-131
-
-
Morris, J.C.1
Roe, C.M.2
Xiong, C.3
Fagan, A.M.4
Goate, A.M.5
-
74
-
-
73549084727
-
Mild cognitive impairment: ten years later
-
Petersen RC, Roberts RO, Knopman DS, Boeve BF, Geda YE, Ivnik RJ, et al. Mild cognitive impairment: ten years later. Arch Neurol. 2009;66:1447-55.
-
(2009)
Arch Neurol
, vol.66
, pp. 1447-1455
-
-
Petersen, R.C.1
Roberts, R.O.2
Knopman, D.S.3
Boeve, B.F.4
Geda, Y.E.5
Ivnik, R.J.6
-
75
-
-
82355192272
-
The Abeta oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease
-
Ferreira ST, Klein WL. The Abeta oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease. Neurobiol Learn Mem. 2011;96:529-43.
-
(2011)
Neurobiol Learn Mem
, vol.96
, pp. 529-543
-
-
Ferreira, S.T.1
Klein, W.L.2
-
76
-
-
84926110620
-
Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease
-
Viola KL, Sbarboro J, Sureka R, De M, Bicca MA, Wang J, et al. Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease. Nat Nanotechnol. 2015;10:91-8.
-
(2015)
Nat Nanotechnol
, vol.10
, pp. 91-98
-
-
Viola, K.L.1
Sbarboro, J.2
Sureka, R.3
De, M.4
Bicca, M.A.5
Wang, J.6
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