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Volumn 1855, Issue 2, 2015, Pages 235-247

Galectin expression in cancer diagnosis and prognosis: A systematic review

Author keywords

Clinical trials; Glycobiology; Overall survival; Patients; Therapy; Tumor

Indexed keywords

ECALECTIN; GALECTIN; GALECTIN 1; GALECTIN 10; GALECTIN 12; GALECTIN 13; GALECTIN 14; GALECTIN 2; GALECTIN 3; GALECTIN 4; GALECTIN 7; GALECTIN 8; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84948728185     PISSN: 0304419X     EISSN: 18792561     Source Type: Journal    
DOI: 10.1016/j.bbcan.2015.03.003     Document Type: Review
Times cited : (259)

References (261)
  • 2
    • 84888294933 scopus 로고    scopus 로고
    • Vascular galectins: regulators of tumor progression and targets for cancer therapy
    • Thijssen V.L., Rabinovich G.A., Griffioen A.W. Vascular galectins: regulators of tumor progression and targets for cancer therapy. Cytokine Growth Factor Rev. 2013, 24:547-558.
    • (2013) Cytokine Growth Factor Rev. , vol.24 , pp. 547-558
    • Thijssen, V.L.1    Rabinovich, G.A.2    Griffioen, A.W.3
  • 3
    • 0027965708 scopus 로고
    • Galectins. Structure and function of a large family of animal lectins
    • Barondes S.H., Cooper D.N., Gitt M.A., Leffler H. Galectins. Structure and function of a large family of animal lectins. J. Biol. Chem. 1994, 269:20807-20810.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20807-20810
    • Barondes, S.H.1    Cooper, D.N.2    Gitt, M.A.3    Leffler, H.4
  • 4
    • 34547111331 scopus 로고    scopus 로고
    • Recognition mechanism of galectin-4 for cholesterol 3-sulfate
    • Ideo H., Seko A., Yamashita K. Recognition mechanism of galectin-4 for cholesterol 3-sulfate. J. Biol. Chem. 2007, 282:21081-21089.
    • (2007) J. Biol. Chem. , vol.282 , pp. 21081-21089
    • Ideo, H.1    Seko, A.2    Yamashita, K.3
  • 5
    • 1642483757 scopus 로고    scopus 로고
    • Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous cross-linked complexes
    • Ahmad N., Gabius H.J., Andre S., Kaltner H., Sabesan S., Roy R., Liu B., Macaluso F., Brewer C.F. Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous cross-linked complexes. J. Biol. Chem. 2004, 279:10841-10847.
    • (2004) J. Biol. Chem. , vol.279 , pp. 10841-10847
    • Ahmad, N.1    Gabius, H.J.2    Andre, S.3    Kaltner, H.4    Sabesan, S.5    Roy, R.6    Liu, B.7    Macaluso, F.8    Brewer, C.F.9
  • 13
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 14
    • 11144241063 scopus 로고    scopus 로고
    • Galectins as modulators of tumour progression
    • Liu F.T., Rabinovich G.A. Galectins as modulators of tumour progression. Nat. Rev. Cancer 2005, 5:29-41.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 29-41
    • Liu, F.T.1    Rabinovich, G.A.2
  • 15
  • 16
    • 84858766894 scopus 로고    scopus 로고
    • Regulatory circuits mediated by lectin-glycan interactions in autoimmunity and cancer
    • Rabinovich G.A., Croci D.O. Regulatory circuits mediated by lectin-glycan interactions in autoimmunity and cancer. Immunity 2012, 36:322-335.
    • (2012) Immunity , vol.36 , pp. 322-335
    • Rabinovich, G.A.1    Croci, D.O.2
  • 17
    • 79952576615 scopus 로고    scopus 로고
    • Inhibition of galectins with small molecules
    • Oberg C.T., Leffler H., Nilsson U.J. Inhibition of galectins with small molecules. Chimia (Aarau) 2011, 65:18-23.
    • (2011) Chimia (Aarau) , vol.65 , pp. 18-23
    • Oberg, C.T.1    Leffler, H.2    Nilsson, U.J.3
  • 22
    • 0038175029 scopus 로고    scopus 로고
    • Truncated galectin-3 inhibits tumor growth and metastasis in orthotopic nude mouse model of human breast cancer
    • John C.M., Leffler H., Kahl-Knutsson B., Svensson I., Jarvis G.A. Truncated galectin-3 inhibits tumor growth and metastasis in orthotopic nude mouse model of human breast cancer. Clin. Cancer Res. 2003, 9:2374-2383.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 2374-2383
    • John, C.M.1    Leffler, H.2    Kahl-Knutsson, B.3    Svensson, I.4    Jarvis, G.A.5
  • 23
    • 79960256372 scopus 로고    scopus 로고
    • Galectin-3C inhibits tumor growth and increases the anticancer activity of bortezomib in a murine model of human multiple myeloma
    • Mirandola L., Yu Y., Chui K., Jenkins M.R., Cobos E., John C.M., Chiriva-Internati M. Galectin-3C inhibits tumor growth and increases the anticancer activity of bortezomib in a murine model of human multiple myeloma. PLoS One 2011, 6:e21811.
    • (2011) PLoS One , vol.6 , pp. e21811
    • Mirandola, L.1    Yu, Y.2    Chui, K.3    Jenkins, M.R.4    Cobos, E.5    John, C.M.6    Chiriva-Internati, M.7
  • 25
    • 0035170375 scopus 로고    scopus 로고
    • Increased expression of galectin-1 in carcinoma-associated stroma predicts poor outcome in prostate carcinoma patients
    • van den BrÛle F.A., Waltregny D., Castronovo V. Increased expression of galectin-1 in carcinoma-associated stroma predicts poor outcome in prostate carcinoma patients. J. Pathol. 2001, 193:80-87.
    • (2001) J. Pathol. , vol.193 , pp. 80-87
    • van den BrÛle, F.A.1    Waltregny, D.2    Castronovo, V.3
  • 33
    • 84856960944 scopus 로고    scopus 로고
    • High expression of Galectin-1 in pancreatic stellate cells plays a role in the development and maintenance of an immunosuppressive microenvironment in pancreatic cancer
    • Tang D., Yuan Z., Xue X., Lu Z., Zhang Y., Wang H., Chen M., An Y., Wei J., Zhu Y., Miao Y., Jiang K. High expression of Galectin-1 in pancreatic stellate cells plays a role in the development and maintenance of an immunosuppressive microenvironment in pancreatic cancer. Int. J. Cancer 2012, 130:2337-2348.
    • (2012) Int. J. Cancer , vol.130 , pp. 2337-2348
    • Tang, D.1    Yuan, Z.2    Xue, X.3    Lu, Z.4    Zhang, Y.5    Wang, H.6    Chen, M.7    An, Y.8    Wei, J.9    Zhu, Y.10    Miao, Y.11    Jiang, K.12
  • 34
    • 10844252383 scopus 로고    scopus 로고
    • Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry
    • Shen J., Person M.D., Zhu J., Abbruzzese J.L., Li D. Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry. Cancer Res. 2004, 64:9018-9026.
    • (2004) Cancer Res. , vol.64 , pp. 9018-9026
    • Shen, J.1    Person, M.D.2    Zhu, J.3    Abbruzzese, J.L.4    Li, D.5
  • 37
    • 84876385628 scopus 로고    scopus 로고
    • The involvement of Galectins in the modulation of the JAK/STAT pathway in myeloproliferative neoplasia
    • Koopmans S.M., Bot F.J., Schouten H.C., Janssen J., van Marion A.M. The involvement of Galectins in the modulation of the JAK/STAT pathway in myeloproliferative neoplasia. Am. J. Blood Res. 2012, 2:119-127.
    • (2012) Am. J. Blood Res. , vol.2 , pp. 119-127
    • Koopmans, S.M.1    Bot, F.J.2    Schouten, H.C.3    Janssen, J.4    van Marion, A.M.5
  • 39
    • 0029781501 scopus 로고    scopus 로고
    • A.K. el-Naggar, G.L. Clayman, R. Lotan, Expression of galectins in head and neck squamous cell carcinoma
    • Gillenwater A., Xu X.C. A.K. el-Naggar, G.L. Clayman, R. Lotan, Expression of galectins in head and neck squamous cell carcinoma. Head Neck 1996, 18:422-432.
    • (1996) Head Neck , vol.18 , pp. 422-432
    • Gillenwater, A.1    Xu, X.C.2
  • 43
    • 77954364289 scopus 로고    scopus 로고
    • Identification of Galectin-1 as a novel biomarker in nasopharyngeal carcinoma by proteomic analysis
    • Tang C.E., Tan T., Li C., Chen Z.C., Ruan L., Wang H.H., Su T., Zhang P.F., Xiao Z.Q. Identification of Galectin-1 as a novel biomarker in nasopharyngeal carcinoma by proteomic analysis. Oncol. Rep. 2010, 24:495-500.
    • (2010) Oncol. Rep. , vol.24 , pp. 495-500
    • Tang, C.E.1    Tan, T.2    Li, C.3    Chen, Z.C.4    Ruan, L.5    Wang, H.H.6    Su, T.7    Zhang, P.F.8    Xiao, Z.Q.9
  • 47
    • 0029157473 scopus 로고
    • A.K. el-Naggar, R. Lotan, Differential expression of galectin-1 and galectin-3 in thyroid tumors. Potential diagnostic implications
    • Xu X.C. A.K. el-Naggar, R. Lotan, Differential expression of galectin-1 and galectin-3 in thyroid tumors. Potential diagnostic implications. Am. J. Pathol. 1995, 147:815-822.
    • (1995) Am. J. Pathol. , vol.147 , pp. 815-822
    • Xu, X.C.1
  • 48
    • 69749085173 scopus 로고    scopus 로고
    • Immunohistochemical fingerprinting of the network of seven adhesion/growth-regulatory lectins in human skin and detection of distinct tumour-associated alterations
    • Cada Z., Smetana K., Lacina L., Plzáková Z., Stork J., Kaltner H., Russwurm R., Lensch M., André S., Gabius H.J. Immunohistochemical fingerprinting of the network of seven adhesion/growth-regulatory lectins in human skin and detection of distinct tumour-associated alterations. Folia Biol. (Praha) 2009, 55:145-152.
    • (2009) Folia Biol. (Praha) , vol.55 , pp. 145-152
    • Cada, Z.1    Smetana, K.2    Lacina, L.3    Plzáková, Z.4    Stork, J.5    Kaltner, H.6    Russwurm, R.7    Lensch, M.8    André, S.9    Gabius, H.J.10
  • 50
    • 0033404665 scopus 로고    scopus 로고
    • The levels of expression of galectin-1, galectin-3, and the Thomsen-Friedenreich antigen and their binding sites decrease as clinical aggressiveness increases in head and neck cancers
    • Choufani G., Nagy N., Saussez S., Marchant H., Bisschop P., Burchert M., Danguy A., Louryan S., Salmon I., Gabius H.J., Kiss R., Hassid S. The levels of expression of galectin-1, galectin-3, and the Thomsen-Friedenreich antigen and their binding sites decrease as clinical aggressiveness increases in head and neck cancers. Cancer 1999, 86:2353-2363.
    • (1999) Cancer , vol.86 , pp. 2353-2363
    • Choufani, G.1    Nagy, N.2    Saussez, S.3    Marchant, H.4    Bisschop, P.5    Burchert, M.6    Danguy, A.7    Louryan, S.8    Salmon, I.9    Gabius, H.J.10    Kiss, R.11    Hassid, S.12
  • 51
    • 84864248735 scopus 로고    scopus 로고
    • Inhibition of uterine sarcoma cell growth through suppression of endogenous tyrosine kinase B signaling
    • Makino K., Kawamura K., Sato W., Kawamura N., Fujimoto T., Terada Y. Inhibition of uterine sarcoma cell growth through suppression of endogenous tyrosine kinase B signaling. PLoS One 2012, 7:e41049.
    • (2012) PLoS One , vol.7 , pp. e41049
    • Makino, K.1    Kawamura, K.2    Sato, W.3    Kawamura, N.4    Fujimoto, T.5    Terada, Y.6
  • 53
    • 67449102212 scopus 로고    scopus 로고
    • Increased expression of galectin-1 is associated with human oral squamous cell carcinoma development
    • Ding Y.M., Dong J.H., Chen L.L., Zhang H.D. Increased expression of galectin-1 is associated with human oral squamous cell carcinoma development. Oncol. Rep. 2009, 21:983-987.
    • (2009) Oncol. Rep. , vol.21 , pp. 983-987
    • Ding, Y.M.1    Dong, J.H.2    Chen, L.L.3    Zhang, H.D.4
  • 54
    • 77956060550 scopus 로고    scopus 로고
    • Overexpression of Galectin-1 is negatively correlated with pathologic differentiation grade in oral squamous cell carcinoma
    • Zhong L.P., Wei K.J., Yang X., Pan H.Y., Ye D.X., Wang L.Z., Zhang Z.Y. Overexpression of Galectin-1 is negatively correlated with pathologic differentiation grade in oral squamous cell carcinoma. J. Cancer Res. Clin. Oncol. 2010, 136:1527-1535.
    • (2010) J. Cancer Res. Clin. Oncol. , vol.136 , pp. 1527-1535
    • Zhong, L.P.1    Wei, K.J.2    Yang, X.3    Pan, H.Y.4    Ye, D.X.5    Wang, L.Z.6    Zhang, Z.Y.7
  • 55
    • 0942297968 scopus 로고    scopus 로고
    • Identification of tumor-associated proteins in oral tongue squamous cell carcinoma by proteomics
    • He Q.Y., Chen J., Kung H.F., Yuen A.P., Chiu J.F. Identification of tumor-associated proteins in oral tongue squamous cell carcinoma by proteomics. Proteomics 2004, 4:271-278.
    • (2004) Proteomics , vol.4 , pp. 271-278
    • He, Q.Y.1    Chen, J.2    Kung, H.F.3    Yuen, A.P.4    Chiu, J.F.5
  • 59
    • 27944496921 scopus 로고    scopus 로고
    • Galectin-3 immunodetection in follicular thyroid neoplasms: a prospective study on fine-needle aspiration samples
    • Collet J.F., Hurbain I., Prengel C., Utzmann O., Scetbon F., Bernaudin J.F., Fajac A. Galectin-3 immunodetection in follicular thyroid neoplasms: a prospective study on fine-needle aspiration samples. Br. J. Cancer 2005, 93:1175-1181.
    • (2005) Br. J. Cancer , vol.93 , pp. 1175-1181
    • Collet, J.F.1    Hurbain, I.2    Prengel, C.3    Utzmann, O.4    Scetbon, F.5    Bernaudin, J.F.6    Fajac, A.7
  • 63
    • 0033159265 scopus 로고    scopus 로고
    • Decreased expression of galectin-3 in basal cell carcinoma of the skin
    • Castronovo V., Liu F.T., van den Brule F.A. Decreased expression of galectin-3 in basal cell carcinoma of the skin. Int. J. Oncol. 1999, 15:67-70.
    • (1999) Int. J. Oncol. , vol.15 , pp. 67-70
    • Castronovo, V.1    Liu, F.T.2    van den Brule, F.A.3
  • 69
    • 0030031430 scopus 로고    scopus 로고
    • Galectin-3, a beta-galactoside-binding animal lectin, is a marker of anaplastic large-cell lymphoma
    • Konstantinov K.N., Robbins B.A., Liu F.T. Galectin-3, a beta-galactoside-binding animal lectin, is a marker of anaplastic large-cell lymphoma. Am. J. Pathol. 1996, 148:25-30.
    • (1996) Am. J. Pathol. , vol.148 , pp. 25-30
    • Konstantinov, K.N.1    Robbins, B.A.2    Liu, F.T.3
  • 73
    • 84870521155 scopus 로고    scopus 로고
    • Galectin-3 binds to CD45 on diffuse large B-cell lymphoma cells to regulate susceptibility to cell death
    • Clark M.C., Pang M., Hsu D.K., Liu F.T., de Vos S., Gascoyne R.D., Said J., Baum L.G. Galectin-3 binds to CD45 on diffuse large B-cell lymphoma cells to regulate susceptibility to cell death. Blood 2012, 120:4635-4644.
    • (2012) Blood , vol.120 , pp. 4635-4644
    • Clark, M.C.1    Pang, M.2    Hsu, D.K.3    Liu, F.T.4    de Vos, S.5    Gascoyne, R.D.6    Said, J.7    Baum, L.G.8
  • 76
    • 49749137921 scopus 로고    scopus 로고
    • Galectin-3: a useful biomarker for differential diagnosis of brain tumors
    • Park S.H., Min H.S., Kim B., Myung J., Paek S.H. Galectin-3: a useful biomarker for differential diagnosis of brain tumors. Neuropathology 2008, 28:497-506.
    • (2008) Neuropathology , vol.28 , pp. 497-506
    • Park, S.H.1    Min, H.S.2    Kim, B.3    Myung, J.4    Paek, S.H.5
  • 77
    • 0027414461 scopus 로고
    • Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma
    • Lotz M.M., Andrews C.W., Korzelius C.A., Lee E.C., Steele G.D., Clarke A., Mercurio A.M. Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma. Proc. Natl. Acad. Sci. U. S. A. 1993, 90:3466-3470.
    • (1993) Proc. Natl. Acad. Sci. U. S. A. , vol.90 , pp. 3466-3470
    • Lotz, M.M.1    Andrews, C.W.2    Korzelius, C.A.3    Lee, E.C.4    Steele, G.D.5    Clarke, A.6    Mercurio, A.M.7
  • 80
    • 58649097509 scopus 로고    scopus 로고
    • Loss of CD7, independent of galectin-3 expression, implies a worse prognosis in adult T-cell leukaemia/lymphoma
    • Liu T.Y., Chen C.Y., Tien H.F., Lin C.W. Loss of CD7, independent of galectin-3 expression, implies a worse prognosis in adult T-cell leukaemia/lymphoma. Histopathology 2009, 54:214-220.
    • (2009) Histopathology , vol.54 , pp. 214-220
    • Liu, T.Y.1    Chen, C.Y.2    Tien, H.F.3    Lin, C.W.4
  • 82
    • 0030744362 scopus 로고    scopus 로고
    • Cloning and expression of the mRNA of human galectin-4, an S-type lectin down-regulated in colorectal cancer
    • Rechreche H., Mallo G.V., Montalto G., Dagorn J.C., Iovanna J.L. Cloning and expression of the mRNA of human galectin-4, an S-type lectin down-regulated in colorectal cancer. Eur. J. Biochem. 1997, 248:225-230.
    • (1997) Eur. J. Biochem. , vol.248 , pp. 225-230
    • Rechreche, H.1    Mallo, G.V.2    Montalto, G.3    Dagorn, J.C.4    Iovanna, J.L.5
  • 83
    • 79959743515 scopus 로고    scopus 로고
    • Galectin-4 functions as a tumor suppressor of human colorectal cancer
    • Satelli A., Rao P.S., Thirumala S., Rao U.S. Galectin-4 functions as a tumor suppressor of human colorectal cancer. Int. J. Cancer 2011, 129:799-809.
    • (2011) Int. J. Cancer , vol.129 , pp. 799-809
    • Satelli, A.1    Rao, P.S.2    Thirumala, S.3    Rao, U.S.4
  • 89
    • 84872867776 scopus 로고    scopus 로고
    • Roles of galectin-7 and S100A9 in cervical squamous carcinoma: Clinicopathological and in vitro evidence
    • Zhu H., Wu T.C., Chen W.Q., Zhou L.J., Wu Y., Zeng L., Pei H.P. Roles of galectin-7 and S100A9 in cervical squamous carcinoma: Clinicopathological and in vitro evidence. Int. J. Cancer 2013, 132:1051-1059.
    • (2013) Int. J. Cancer , vol.132 , pp. 1051-1059
    • Zhu, H.1    Wu, T.C.2    Chen, W.Q.3    Zhou, L.J.4    Wu, Y.5    Zeng, L.6    Pei, H.P.7
  • 90
    • 84884685865 scopus 로고    scopus 로고
    • Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer
    • Kim S.J., Hwang J.A., Ro J.Y., Lee Y.S., Chun K.H. Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer. Oncotarget 2013, 4:1461-1471.
    • (2013) Oncotarget , vol.4 , pp. 1461-1471
    • Kim, S.J.1    Hwang, J.A.2    Ro, J.Y.3    Lee, Y.S.4    Chun, K.H.5
  • 91
    • 77954638391 scopus 로고    scopus 로고
    • Identification of galectin-7 as a potential biomarker for esophageal squamous cell carcinoma by proteomic analysis
    • Zhu X., Ding M., Yu M.L., Feng M.X., Tan L.J., Zhao F.K. Identification of galectin-7 as a potential biomarker for esophageal squamous cell carcinoma by proteomic analysis. BMC Cancer 2010, 10:290.
    • (2010) BMC Cancer , vol.10 , pp. 290
    • Zhu, X.1    Ding, M.2    Yu, M.L.3    Feng, M.X.4    Tan, L.J.5    Zhao, F.K.6
  • 92
    • 77953192508 scopus 로고    scopus 로고
    • Overexpression of galectin-7, a myoepithelial cell marker, enhances spontaneous metastasis of breast cancer cells
    • Demers M., Rose A.A., Grosset A.A., Biron-Pain K., Gaboury L., Siegel P.M., St-Pierre Y. Overexpression of galectin-7, a myoepithelial cell marker, enhances spontaneous metastasis of breast cancer cells. Am. J. Pathol. 2010, 176:3023-3031.
    • (2010) Am. J. Pathol. , vol.176 , pp. 3023-3031
    • Demers, M.1    Rose, A.A.2    Grosset, A.A.3    Biron-Pain, K.4    Gaboury, L.5    Siegel, P.M.6    St-Pierre, Y.7
  • 95
    • 34047256445 scopus 로고    scopus 로고
    • Galectin-7 in lymphoma: elevated expression in human lymphoid malignancies and decreased lymphoma dissemination by antisense strategies in experimental model
    • Demers M., Biron-Pain K., Hébert J., Lamarre A., Magnaldo T., St-Pierre Y. Galectin-7 in lymphoma: elevated expression in human lymphoid malignancies and decreased lymphoma dissemination by antisense strategies in experimental model. Cancer Res. 2007, 67:2824-2829.
    • (2007) Cancer Res. , vol.67 , pp. 2824-2829
    • Demers, M.1    Biron-Pain, K.2    Hébert, J.3    Lamarre, A.4    Magnaldo, T.5    St-Pierre, Y.6
  • 96
    • 33847009130 scopus 로고    scopus 로고
    • Sensitizing effect of galectin-7 in urothelial cancer to cisplatin through the accumulation of intracellular reactive oxygen species
    • Matsui Y., Ueda S., Watanabe J., Kuwabara I., Ogawa O., Nishiyama H. Sensitizing effect of galectin-7 in urothelial cancer to cisplatin through the accumulation of intracellular reactive oxygen species. Cancer Res. 2007, 67:1212-1220.
    • (2007) Cancer Res. , vol.67 , pp. 1212-1220
    • Matsui, Y.1    Ueda, S.2    Watanabe, J.3    Kuwabara, I.4    Ogawa, O.5    Nishiyama, H.6
  • 102
    • 77955516209 scopus 로고    scopus 로고
    • Antibody responses to galectin-8, TARP and TRAP1 in prostate cancer patients treated with a GM-CSF-secreting cellular immunotherapy
    • Nguyen M.C., Tu G.H., Koprivnikar K.E., Gonzalez-Edick M., Jooss K.U., Harding T.C. Antibody responses to galectin-8, TARP and TRAP1 in prostate cancer patients treated with a GM-CSF-secreting cellular immunotherapy. Cancer Immunol. Immunother. 2010, 59:1313-1323.
    • (2010) Cancer Immunol. Immunother. , vol.59 , pp. 1313-1323
    • Nguyen, M.C.1    Tu, G.H.2    Koprivnikar, K.E.3    Gonzalez-Edick, M.4    Jooss, K.U.5    Harding, T.C.6
  • 104
    • 84904385885 scopus 로고    scopus 로고
    • Role of downregulation of galectin-9 in the tumorigenesis of gastric cancer
    • Yang J., Zhu L., Cai Y., Suo J., Jin J. Role of downregulation of galectin-9 in the tumorigenesis of gastric cancer. Int. J. Oncol. 2014, 45:1313-1320.
    • (2014) Int. J. Oncol. , vol.45 , pp. 1313-1320
    • Yang, J.1    Zhu, L.2    Cai, Y.3    Suo, J.4    Jin, J.5
  • 105
    • 84892411125 scopus 로고    scopus 로고
    • Decreased galectin-9 and increased tim-3 expression are related to poor prognosis in gastric cancer
    • Jiang J., Jin M.S., Kong F., Cao D., Ma H.X., Jia Z., Wang Y.P., Suo J., Cao X. Decreased galectin-9 and increased tim-3 expression are related to poor prognosis in gastric cancer. PLoS One 2013, 8:e81799.
    • (2013) PLoS One , vol.8 , pp. e81799
    • Jiang, J.1    Jin, M.S.2    Kong, F.3    Cao, D.4    Ma, H.X.5    Jia, Z.6    Wang, Y.P.7    Suo, J.8    Cao, X.9
  • 108
    • 84899064113 scopus 로고    scopus 로고
    • Changed expression of E-cadherin and galectin-9 in oral squamous cell carcinomas but lack of potential as prognostic markers
    • Chan S.W., Kallarakkal T.G., Abraham M.T. Changed expression of E-cadherin and galectin-9 in oral squamous cell carcinomas but lack of potential as prognostic markers. Asian Pac. J. Cancer Prev. 2014, 15:2145-2152.
    • (2014) Asian Pac. J. Cancer Prev. , vol.15 , pp. 2145-2152
    • Chan, S.W.1    Kallarakkal, T.G.2    Abraham, M.T.3
  • 110
    • 0042291641 scopus 로고    scopus 로고
    • Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease
    • Türeci O., Schmitt H., Fadle N., Pfreundschuh M., Sahin U. Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease. J. Biol. Chem. 1997, 272:6416-6422.
    • (1997) J. Biol. Chem. , vol.272 , pp. 6416-6422
    • Türeci, O.1    Schmitt, H.2    Fadle, N.3    Pfreundschuh, M.4    Sahin, U.5
  • 113
    • 84887914597 scopus 로고    scopus 로고
    • Bisected, complex N-glycans and galectins in mouse mammary tumor progression and human breast cancer
    • Miwa H.E., Koba W.R., Fine E.J., Giricz O., Kenny P.A., Stanley P. Bisected, complex N-glycans and galectins in mouse mammary tumor progression and human breast cancer. Glycobiology 2013, 23:1477-1490.
    • (2013) Glycobiology , vol.23 , pp. 1477-1490
    • Miwa, H.E.1    Koba, W.R.2    Fine, E.J.3    Giricz, O.4    Kenny, P.A.5    Stanley, P.6
  • 115
    • 0029073986 scopus 로고
    • Expression of an endogenous galactose-binding lectin correlates with neoplastic progression in the colon
    • Schoeppner H.L., Raz A., Ho S.B., Bresalier R.S. Expression of an endogenous galactose-binding lectin correlates with neoplastic progression in the colon. Cancer 1995, 75:2818-2826.
    • (1995) Cancer , vol.75 , pp. 2818-2826
    • Schoeppner, H.L.1    Raz, A.2    Ho, S.B.3    Bresalier, R.S.4
  • 118
    • 33645811957 scopus 로고    scopus 로고
    • Reduced galectin-3 expression is an indicator of unfavorable prognosis in gastric cancer
    • Okada K., Shimura T., Suehiro T., Mochiki E., Kuwano H. Reduced galectin-3 expression is an indicator of unfavorable prognosis in gastric cancer. Anticancer Res. 2006, 26:1369-1376.
    • (2006) Anticancer Res. , vol.26 , pp. 1369-1376
    • Okada, K.1    Shimura, T.2    Suehiro, T.3    Mochiki, E.4    Kuwano, H.5
  • 119
    • 0030872450 scopus 로고    scopus 로고
    • Expression of the endogenous galactose-binding protein galectin-3 correlates with the malignant potential of tumors in the central nervous system
    • Bresalier R.S., Yan P.S., Byrd J.C., Lotan R., Raz A. Expression of the endogenous galactose-binding protein galectin-3 correlates with the malignant potential of tumors in the central nervous system. Cancer 1997, 80:776-787.
    • (1997) Cancer , vol.80 , pp. 776-787
    • Bresalier, R.S.1    Yan, P.S.2    Byrd, J.C.3    Lotan, R.4    Raz, A.5
  • 124
    • 78149410574 scopus 로고    scopus 로고
    • CD24 and galectin-1 expressions in gastric adenocarcinoma and clinicopathologic significance
    • Bektas S., Bahadir B., Ucan B.H., Ozdamar S.O. CD24 and galectin-1 expressions in gastric adenocarcinoma and clinicopathologic significance. Pathol. Oncol. Res. 2010, 16:569-577.
    • (2010) Pathol. Oncol. Res. , vol.16 , pp. 569-577
    • Bektas, S.1    Bahadir, B.2    Ucan, B.H.3    Ozdamar, S.O.4
  • 126
    • 84876378081 scopus 로고    scopus 로고
    • Clinicopathological and prognostic significance of galectin-1 and vascular endothelial growth factor expression in gastric cancer
    • Chen J., Zhou S.J., Zhang Y., Zhang G.Q., Zha T.Z., Feng Y.Z., Zhang K. Clinicopathological and prognostic significance of galectin-1 and vascular endothelial growth factor expression in gastric cancer. World J. Gastroenterol. 2013, 19:2073-2079.
    • (2013) World J. Gastroenterol. , vol.19 , pp. 2073-2079
    • Chen, J.1    Zhou, S.J.2    Zhang, Y.3    Zhang, G.Q.4    Zha, T.Z.5    Feng, Y.Z.6    Zhang, K.7
  • 127
    • 84891754332 scopus 로고    scopus 로고
    • Galectin-1 overexpression promotes progression and chemoresistance to cisplatin in epithelial ovarian cancer
    • Zhang P., Zhang P., Shi B., Zhou M., Jiang H., Zhang H., Pan X., Gao H., Sun H., Li Z. Galectin-1 overexpression promotes progression and chemoresistance to cisplatin in epithelial ovarian cancer. Cell Death Dis. 2014, 5:e991.
    • (2014) Cell Death Dis. , vol.5 , pp. e991
    • Zhang, P.1    Zhang, P.2    Shi, B.3    Zhou, M.4    Jiang, H.5    Zhang, H.6    Pan, X.7    Gao, H.8    Sun, H.9    Li, Z.10
  • 129
    • 84907435684 scopus 로고    scopus 로고
    • Galectin expression profiling identifies galectin-1 and galectin-9{increment}5 as prognostic factors in stage I/II non-small cell lung cancer
    • Schulkens I.A., Heusschen R., van den Boogaart V., van Suylen R., Dingemans A.D., Griffioen A.W., Thijssen V.L. Galectin expression profiling identifies galectin-1 and galectin-9{increment}5 as prognostic factors in stage I/II non-small cell lung cancer. PLoS One 2014, 9:e107988.
    • (2014) PLoS One , vol.9 , pp. e107988
    • Schulkens, I.A.1    Heusschen, R.2    van den Boogaart, V.3    van Suylen, R.4    Dingemans, A.D.5    Griffioen, A.W.6    Thijssen, V.L.7
  • 135
    • 84895786672 scopus 로고    scopus 로고
    • Galectin-1 has potential prognostic significance and is implicated in clear cell renal cell carcinoma progression through the HIF/mTOR signaling axis
    • White N.M., Masui O., Newsted D., Scorilas A., Romaschin A.D., Bjarnason G.A., Siu K.W., Yousef G.M. Galectin-1 has potential prognostic significance and is implicated in clear cell renal cell carcinoma progression through the HIF/mTOR signaling axis. Br. J. Cancer 2014, 110:1250-1259.
    • (2014) Br. J. Cancer , vol.110 , pp. 1250-1259
    • White, N.M.1    Masui, O.2    Newsted, D.3    Scorilas, A.4    Romaschin, A.D.5    Bjarnason, G.A.6    Siu, K.W.7    Yousef, G.M.8
  • 140
    • 84898015707 scopus 로고    scopus 로고
    • Galectin-1 overexpression in nasopharyngeal carcinoma: effect on survival
    • Chang S.L., Li C.F., Lin C., Lin Y.S. Galectin-1 overexpression in nasopharyngeal carcinoma: effect on survival. Acta Otolaryngol. 2014, 134:536-542.
    • (2014) Acta Otolaryngol. , vol.134 , pp. 536-542
    • Chang, S.L.1    Li, C.F.2    Lin, C.3    Lin, Y.S.4
  • 141
    • 84866276661 scopus 로고    scopus 로고
    • Prognostic significance of galectin-3 and cyclin D1 expression in undifferentiated nasopharyngeal carcinoma
    • Acikalin M.F., Etiz D., Gurbuz M.K., Ozudogru E., Canaz F., Colak E. Prognostic significance of galectin-3 and cyclin D1 expression in undifferentiated nasopharyngeal carcinoma. Med. Oncol. 2012, 29:742-749.
    • (2012) Med. Oncol. , vol.29 , pp. 742-749
    • Acikalin, M.F.1    Etiz, D.2    Gurbuz, M.K.3    Ozudogru, E.4    Canaz, F.5    Colak, E.6
  • 143
    • 1842866297 scopus 로고    scopus 로고
    • Galectin-3: differential expression between small-cell and non-small-cell lung cancer
    • Buttery R., Monaghan H., Salter D.M., Sethi T. Galectin-3: differential expression between small-cell and non-small-cell lung cancer. Histopathology 2004, 44:339-344.
    • (2004) Histopathology , vol.44 , pp. 339-344
    • Buttery, R.1    Monaghan, H.2    Salter, D.M.3    Sethi, T.4
  • 145
    • 84888288249 scopus 로고    scopus 로고
    • Galectin-1 is an independent prognostic factor for local recurrence and survival after definitive radiation therapy for patients with squamous cell carcinoma of the uterine cervix
    • Huang E.Y., Chanchien C.C., Lin H., Wang C.C., Wang C.J., Huang C.C. Galectin-1 is an independent prognostic factor for local recurrence and survival after definitive radiation therapy for patients with squamous cell carcinoma of the uterine cervix. Int. J. Radiat. Oncol. Biol. Phys. 2013, 87:975-982.
    • (2013) Int. J. Radiat. Oncol. Biol. Phys. , vol.87 , pp. 975-982
    • Huang, E.Y.1    Chanchien, C.C.2    Lin, H.3    Wang, C.C.4    Wang, C.J.5    Huang, C.C.6
  • 148
    • 84859849194 scopus 로고    scopus 로고
    • Galectin-1 inhibits the viability, proliferation, and Th1 cytokine production of nonmalignant T cells in patients with leukemic cutaneous T-cell lymphoma
    • Cedeno-Laurent F., Watanabe R., Teague J.E., Kupper T.S., Clark R.A., Dimitroff C.J. Galectin-1 inhibits the viability, proliferation, and Th1 cytokine production of nonmalignant T cells in patients with leukemic cutaneous T-cell lymphoma. Blood 2012, 119:3534-3538.
    • (2012) Blood , vol.119 , pp. 3534-3538
    • Cedeno-Laurent, F.1    Watanabe, R.2    Teague, J.E.3    Kupper, T.S.4    Clark, R.A.5    Dimitroff, C.J.6
  • 151
    • 81255138301 scopus 로고    scopus 로고
    • Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium
    • Barrow H., Guo X., Wandall H.H., Pedersen J.W., Fu B., Zhao Q., Chen C., Rhodes J.M., Yu L.G. Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium. Clin. Cancer Res. 2011, 17:7035-7046.
    • (2011) Clin. Cancer Res. , vol.17 , pp. 7035-7046
    • Barrow, H.1    Guo, X.2    Wandall, H.H.3    Pedersen, J.W.4    Fu, B.5    Zhao, Q.6    Chen, C.7    Rhodes, J.M.8    Yu, L.G.9
  • 152
    • 84877097538 scopus 로고    scopus 로고
    • Increased circulation of galectin-3 in cancer induces secretion of metastasis-promoting cytokines from blood vascular endothelium
    • Chen C., Duckworth C.A., Zhao Q., Pritchard D.M., Rhodes J.M., Yu L.G. Increased circulation of galectin-3 in cancer induces secretion of metastasis-promoting cytokines from blood vascular endothelium. Clin. Cancer Res. 2013, 19:1693-1704.
    • (2013) Clin. Cancer Res. , vol.19 , pp. 1693-1704
    • Chen, C.1    Duckworth, C.A.2    Zhao, Q.3    Pritchard, D.M.4    Rhodes, J.M.5    Yu, L.G.6
  • 155
    • 4444360281 scopus 로고    scopus 로고
    • Great Lakes-New England Clinical and Epidemiology Center of the Early Detection Research Network, A circulating ligand for galectin-3 is a haptoglobin-related glycoprotein elevated in individuals with colon cancer
    • Bresalier R.S., Byrd J.C., Tessler D., Lebel J., Koomen J., Hawke D., Half E., Liu K.F., Mazurek N. Great Lakes-New England Clinical and Epidemiology Center of the Early Detection Research Network, A circulating ligand for galectin-3 is a haptoglobin-related glycoprotein elevated in individuals with colon cancer. Gastroenterology 2004, 127:741-748.
    • (2004) Gastroenterology , vol.127 , pp. 741-748
    • Bresalier, R.S.1    Byrd, J.C.2    Tessler, D.3    Lebel, J.4    Koomen, J.5    Hawke, D.6    Half, E.7    Liu, K.F.8    Mazurek, N.9
  • 158
    • 0036569698 scopus 로고    scopus 로고
    • Expression of 90K (Mac-2 BP) correlates with distant metastasis and predicts survival in stage I non-small cell lung cancer patients
    • Marchetti A., Tinari N., Buttitta F., Chella A., Angeletti C.A., Sacco R., Mucilli F., Ullrich A., Iacobelli S. Expression of 90K (Mac-2 BP) correlates with distant metastasis and predicts survival in stage I non-small cell lung cancer patients. Cancer Res. 2002, 62:2535-2539.
    • (2002) Cancer Res. , vol.62 , pp. 2535-2539
    • Marchetti, A.1    Tinari, N.2    Buttitta, F.3    Chella, A.4    Angeletti, C.A.5    Sacco, R.6    Mucilli, F.7    Ullrich, A.8    Iacobelli, S.9
  • 161
    • 23844503275 scopus 로고    scopus 로고
    • Cancer cell-secreted proteomes as a basis for searching potential tumor markers: nasopharyngeal carcinoma as a model
    • Wu C.C., Chien K.Y., Tsang N.M., Chang K.P., Hao S.P., Tsao C.H., Chang Y.S., Yu J.S. Cancer cell-secreted proteomes as a basis for searching potential tumor markers: nasopharyngeal carcinoma as a model. Proteomics 2005, 5:3173-3182.
    • (2005) Proteomics , vol.5 , pp. 3173-3182
    • Wu, C.C.1    Chien, K.Y.2    Tsang, N.M.3    Chang, K.P.4    Hao, S.P.5    Tsao, C.H.6    Chang, Y.S.7    Yu, J.S.8
  • 162
    • 78649334474 scopus 로고    scopus 로고
    • Serum Cyfra 21.1 and galectin-3 protein levels in relation to immunohistochemical cytokeratin 19 and galectin-3 expression in patients with thyroid tumors
    • Išić T., Savin S., Cvejić D., Marečko I., Tatić S., Havelka M., Paunović I. Serum Cyfra 21.1 and galectin-3 protein levels in relation to immunohistochemical cytokeratin 19 and galectin-3 expression in patients with thyroid tumors. J. Cancer Res. Clin. Oncol. 2010, 136:1805-1812.
    • (2010) J. Cancer Res. Clin. Oncol. , vol.136 , pp. 1805-1812
    • Išić, T.1    Savin, S.2    Cvejić, D.3    Marečko, I.4    Tatić, S.5    Havelka, M.6    Paunović, I.7
  • 164
    • 37049015985 scopus 로고    scopus 로고
    • The determination of the levels of circulating galectin-1 and -3 in HNSCC patients could be used to monitor tumor progression and/or responses to therapy
    • Saussez S., Lorfevre F., Lequeux T., Laurent G., Chantrain G., Vertongen F., Toubeau G., Decaestecker C., Kiss R. The determination of the levels of circulating galectin-1 and -3 in HNSCC patients could be used to monitor tumor progression and/or responses to therapy. Oral Oncol. 2008, 44:86-93.
    • (2008) Oral Oncol. , vol.44 , pp. 86-93
    • Saussez, S.1    Lorfevre, F.2    Lequeux, T.3    Laurent, G.4    Chantrain, G.5    Vertongen, F.6    Toubeau, G.7    Decaestecker, C.8    Kiss, R.9
  • 167
    • 0033572093 scopus 로고    scopus 로고
    • The NH2 terminus of galectin-3 governs cellular compartmentalization and functions in cancer cells
    • Gong H.C., Honjo Y., Nangia-Makker P., Hogan V., Mazurak N., Bresalier R.S., Raz A. The NH2 terminus of galectin-3 governs cellular compartmentalization and functions in cancer cells. Cancer Res. 1999, 59:6239-6245.
    • (1999) Cancer Res. , vol.59 , pp. 6239-6245
    • Gong, H.C.1    Honjo, Y.2    Nangia-Makker, P.3    Hogan, V.4    Mazurak, N.5    Bresalier, R.S.6    Raz, A.7
  • 169
    • 79959379129 scopus 로고    scopus 로고
    • Galectin-3 secretion and tyrosine phosphorylation is dependent on the calpain small subunit, Calpain 4
    • Menon S., Kang C.M., Beningo K.A. Galectin-3 secretion and tyrosine phosphorylation is dependent on the calpain small subunit, Calpain 4. Biochem. Biophys. Res. Commun. 2011, 410:91-96.
    • (2011) Biochem. Biophys. Res. Commun. , vol.410 , pp. 91-96
    • Menon, S.1    Kang, C.M.2    Beningo, K.A.3
  • 170
    • 84871600171 scopus 로고    scopus 로고
    • The two endocytic pathways mediated by the carbohydrate recognition domain and regulated by the collagen-like domain of galectin-3 in vascular endothelial cells
    • Gao X., Liu D., Fan Y., Li X., Xue H., Ma Y., Zhou Y., Tai G. The two endocytic pathways mediated by the carbohydrate recognition domain and regulated by the collagen-like domain of galectin-3 in vascular endothelial cells. PLoS One 2012, 7:e52430.
    • (2012) PLoS One , vol.7 , pp. e52430
    • Gao, X.1    Liu, D.2    Fan, Y.3    Li, X.4    Xue, H.5    Ma, Y.6    Zhou, Y.7    Tai, G.8
  • 171
    • 84887950623 scopus 로고    scopus 로고
    • Phosphorylation and externalization of galectin-4 is controlled by Src family kinases
    • Ideo H., Hoshi I., Yamashita K., Sakamoto M. Phosphorylation and externalization of galectin-4 is controlled by Src family kinases. Glycobiology 2013, 23:1452-1462.
    • (2013) Glycobiology , vol.23 , pp. 1452-1462
    • Ideo, H.1    Hoshi, I.2    Yamashita, K.3    Sakamoto, M.4
  • 172
    • 33748195979 scopus 로고    scopus 로고
    • Glycosylation in cellular mechanisms of health and disease
    • Ohtsubo K., Marth J.D. Glycosylation in cellular mechanisms of health and disease. Cell 2006, 126:855-867.
    • (2006) Cell , vol.126 , pp. 855-867
    • Ohtsubo, K.1    Marth, J.D.2
  • 173
    • 20844437106 scopus 로고    scopus 로고
    • Glycans in cancer and inflammation-potential for therapeutics and diagnostics
    • Dube D.H., Bertozzi C.R. Glycans in cancer and inflammation-potential for therapeutics and diagnostics. Nat. Rev. Drug Discov. 2005, 4:477-488.
    • (2005) Nat. Rev. Drug Discov. , vol.4 , pp. 477-488
    • Dube, D.H.1    Bertozzi, C.R.2
  • 178
    • 0032823402 scopus 로고    scopus 로고
    • Galectins-1 and -3 and their ligands in tumor biology. Non-uniform properties in cell-surface presentation and modulation of adhesion to matrix glycoproteins for various tumor cell lines, in biodistribution of free and liposome-bound galectins and in their expression by breast and colorectal carcinomas with/without metastatic propensity
    • André S., Kojima S., Yamazaki N., Fink C., Kaltner H., Kayser K., Gabius H.J. Galectins-1 and -3 and their ligands in tumor biology. Non-uniform properties in cell-surface presentation and modulation of adhesion to matrix glycoproteins for various tumor cell lines, in biodistribution of free and liposome-bound galectins and in their expression by breast and colorectal carcinomas with/without metastatic propensity. J. Cancer Res. Clin. Oncol. 1999, 125:461-474.
    • (1999) J. Cancer Res. Clin. Oncol. , vol.125 , pp. 461-474
    • André, S.1    Kojima, S.2    Yamazaki, N.3    Fink, C.4    Kaltner, H.5    Kayser, K.6    Gabius, H.J.7
  • 180
  • 183
    • 84877068117 scopus 로고    scopus 로고
    • Simultaneous determination of serum galectin-3 and -4 levels detects metastases in colorectal cancer patients
    • Barrow H., Rhodes J.M., Yu L.G. Simultaneous determination of serum galectin-3 and -4 levels detects metastases in colorectal cancer patients. Cell Oncol. (Dordr) 2013, 36:9-13.
    • (2013) Cell Oncol. (Dordr) , vol.36 , pp. 9-13
    • Barrow, H.1    Rhodes, J.M.2    Yu, L.G.3
  • 186
    • 0035829731 scopus 로고    scopus 로고
    • Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation
    • Paz A., Haklai R., Elad-Sfadia G., Ballan E., Kloog Y. Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation. Oncogene 2001, 20:7486-7493.
    • (2001) Oncogene , vol.20 , pp. 7486-7493
    • Paz, A.1    Haklai, R.2    Elad-Sfadia, G.3    Ballan, E.4    Kloog, Y.5
  • 187
    • 82655173829 scopus 로고    scopus 로고
    • Galectin-3-a jack-of-all-trades in cancer
    • Newlaczyl A.U., Yu L.G. Galectin-3-a jack-of-all-trades in cancer. Cancer Lett. 2011, 313:123-128.
    • (2011) Cancer Lett. , vol.313 , pp. 123-128
    • Newlaczyl, A.U.1    Yu, L.G.2
  • 189
  • 191
    • 74949118349 scopus 로고    scopus 로고
    • Inhibiting tumor growth by targeting tumor vasculature with galectin-1 antagonist anginex conjugated to the cytotoxic acylfulvene, 6-hydroxylpropylacylfulvene
    • Dings R.P., Van Laar E.S., Loren M., Webber J., Zhang Y., Waters S.J., Macdonald J.R., Mayo K.H. Inhibiting tumor growth by targeting tumor vasculature with galectin-1 antagonist anginex conjugated to the cytotoxic acylfulvene, 6-hydroxylpropylacylfulvene. Bioconjug. Chem. 2010, 21:20-27.
    • (2010) Bioconjug. Chem. , vol.21 , pp. 20-27
    • Dings, R.P.1    Van Laar, E.S.2    Loren, M.3    Webber, J.4    Zhang, Y.5    Waters, S.J.6    Macdonald, J.R.7    Mayo, K.H.8
  • 193
    • 20344384247 scopus 로고    scopus 로고
    • Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs
    • Glinskii O.V., Huxley V.H., Glinsky G.V., Pienta K.J., Raz A., Glinsky V.V. Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs. Neoplasia 2005, 7:522-527.
    • (2005) Neoplasia , vol.7 , pp. 522-527
    • Glinskii, O.V.1    Huxley, V.H.2    Glinsky, G.V.3    Pienta, K.J.4    Raz, A.5    Glinsky, V.V.6
  • 195
    • 79952712906 scopus 로고    scopus 로고
    • Targeting galectin-1 in carcinoma-associated fibroblasts inhibits oral squamous cell carcinoma metastasis by downregulating MCP-1/CCL2 expression
    • Wu M.H., Hong H.C., Hong T.M., Chiang W.F., Jin Y.T., Chen Y.L. Targeting galectin-1 in carcinoma-associated fibroblasts inhibits oral squamous cell carcinoma metastasis by downregulating MCP-1/CCL2 expression. Clin. Cancer Res. 2011, 17:1306-1316.
    • (2011) Clin. Cancer Res. , vol.17 , pp. 1306-1316
    • Wu, M.H.1    Hong, H.C.2    Hong, T.M.3    Chiang, W.F.4    Jin, Y.T.5    Chen, Y.L.6
  • 196
    • 84863718828 scopus 로고    scopus 로고
    • Inhibiting galectin-1 reduces murine lung metastasis with increased CD4(+) and CD8 (+) T cells and reduced cancer cell adherence
    • Ito K., Ralph S.J. Inhibiting galectin-1 reduces murine lung metastasis with increased CD4(+) and CD8 (+) T cells and reduced cancer cell adherence. Clin. Exp. Metastasis 2012, 29:561-572.
    • (2012) Clin. Exp. Metastasis , vol.29 , pp. 561-572
    • Ito, K.1    Ralph, S.J.2
  • 197
    • 63449129739 scopus 로고    scopus 로고
    • Inhibitory effect of modified citrus pectin on liver metastases in a mouse colon cancer model
    • Liu H.Y., Huang Z.L., Yang G.H., Lu W.Q., Yu N.R. Inhibitory effect of modified citrus pectin on liver metastases in a mouse colon cancer model. World J. Gastroenterol. 2008, 14:7386-7391.
    • (2008) World J. Gastroenterol. , vol.14 , pp. 7386-7391
    • Liu, H.Y.1    Huang, Z.L.2    Yang, G.H.3    Lu, W.Q.4    Yu, N.R.5
  • 199
    • 84861543054 scopus 로고    scopus 로고
    • Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration
    • Altman D.G., McShane L.M., Sauerbrei W., Taube S.E. Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration. PLoS Med. 2012, 9:e1001216.
    • (2012) PLoS Med. , vol.9 , pp. e1001216
    • Altman, D.G.1    McShane, L.M.2    Sauerbrei, W.3    Taube, S.E.4
  • 202
    • 78049518934 scopus 로고    scopus 로고
    • Cleavage of galectin-3 by matrix metalloproteases induces angiogenesis in breast cancer
    • Nangia-Makker P., Wang Y., Raz T., Tait L., Balan V., Hogan V., Raz A. Cleavage of galectin-3 by matrix metalloproteases induces angiogenesis in breast cancer. Int. J. Cancer 2010, 127:2530-2541.
    • (2010) Int. J. Cancer , vol.127 , pp. 2530-2541
    • Nangia-Makker, P.1    Wang, Y.2    Raz, T.3    Tait, L.4    Balan, V.5    Hogan, V.6    Raz, A.7
  • 203
    • 84870051940 scopus 로고    scopus 로고
    • Galectin-3 genetic variants are associated with platinum-based chemotherapy response and prognosis in patients with NSCLC
    • Wu F., Hu N., Li Y., Bian B., Xu G., Zheng Y. Galectin-3 genetic variants are associated with platinum-based chemotherapy response and prognosis in patients with NSCLC. Cell Oncol. (Dordr) 2012, 35:175-180.
    • (2012) Cell Oncol. (Dordr) , vol.35 , pp. 175-180
    • Wu, F.1    Hu, N.2    Li, Y.3    Bian, B.4    Xu, G.5    Zheng, Y.6
  • 204
    • 84880330643 scopus 로고    scopus 로고
    • Galectin-3 accelerates the progression of oral tongue squamous cell carcinoma via a Wnt/β-catenin-dependent pathway
    • Wang L.P., Chen S.W., Zhuang S.M., Li H., Song M. Galectin-3 accelerates the progression of oral tongue squamous cell carcinoma via a Wnt/β-catenin-dependent pathway. Pathol. Oncol. Res. 2013, 19:461-474.
    • (2013) Pathol. Oncol. Res. , vol.19 , pp. 461-474
    • Wang, L.P.1    Chen, S.W.2    Zhuang, S.M.3    Li, H.4    Song, M.5
  • 205
    • 40749138127 scopus 로고    scopus 로고
    • Overexpression of galectin-1 at the tumor invasion front is associated with poor prognosis in early-stage oral squamous cell carcinoma
    • Chiang W.F., Liu S.Y., Fang L.Y., Lin C.N., Wu M.H., Chen Y.C., Chen Y.L., Jin Y.T. Overexpression of galectin-1 at the tumor invasion front is associated with poor prognosis in early-stage oral squamous cell carcinoma. Oral Oncol. 2008, 44:325-334.
    • (2008) Oral Oncol. , vol.44 , pp. 325-334
    • Chiang, W.F.1    Liu, S.Y.2    Fang, L.Y.3    Lin, C.N.4    Wu, M.H.5    Chen, Y.C.6    Chen, Y.L.7    Jin, Y.T.8
  • 206
    • 28244496108 scopus 로고    scopus 로고
    • Expression of galectin-3 in adenoid cystic carcinoma of the head and neck and its relationship with distant metastasis
    • Teymoortash A., Pientka A., Schrader C., Tiemann M., Werner J.A. Expression of galectin-3 in adenoid cystic carcinoma of the head and neck and its relationship with distant metastasis. J. Cancer Res. Clin. Oncol. 2006, 132:51-56.
    • (2006) J. Cancer Res. Clin. Oncol. , vol.132 , pp. 51-56
    • Teymoortash, A.1    Pientka, A.2    Schrader, C.3    Tiemann, M.4    Werner, J.A.5
  • 209
    • 41149157015 scopus 로고    scopus 로고
    • Proteomic analysis to identify biomarker proteins in pancreatic ductal adenocarcinoma
    • Chung J.C., Oh M.J., Choi S.H., Bae C.D. Proteomic analysis to identify biomarker proteins in pancreatic ductal adenocarcinoma. ANZ J. Surg. 2008, 78:245-251.
    • (2008) ANZ J. Surg. , vol.78 , pp. 245-251
    • Chung, J.C.1    Oh, M.J.2    Choi, S.H.3    Bae, C.D.4
  • 210
    • 84865016312 scopus 로고    scopus 로고
    • Overexpressed galectin-3 in pancreatic cancer induces cell proliferation and invasion by binding Ras and activating Ras signaling
    • Song S., Ji B., Ramachandran V., Wang H., Hafley M., Logsdon C., Bresalier R.S. Overexpressed galectin-3 in pancreatic cancer induces cell proliferation and invasion by binding Ras and activating Ras signaling. PLoS One 2012, 7:e42699.
    • (2012) PLoS One , vol.7 , pp. e42699
    • Song, S.1    Ji, B.2    Ramachandran, V.3    Wang, H.4    Hafley, M.5    Logsdon, C.6    Bresalier, R.S.7
  • 212
    • 0031886393 scopus 로고    scopus 로고
    • Localization of galectin-3 in normal and diseased pancreatic tissue
    • Schaffert C., Pour P.M., Chaney W.G. Localization of galectin-3 in normal and diseased pancreatic tissue. Int. J. Pancreatol. 1998, 23:1-9.
    • (1998) Int. J. Pancreatol. , vol.23 , pp. 1-9
    • Schaffert, C.1    Pour, P.M.2    Chaney, W.G.3
  • 213
    • 79957895865 scopus 로고    scopus 로고
    • Galectin-3 regulates MUC1 and EGFR cellular distribution and EGFR downstream pathways in pancreatic cancer cells
    • Merlin J., Stechly L., de Beaucé S., Monté D., Leteurtre E., van Seuningen I., Huet G., Pigny P. Galectin-3 regulates MUC1 and EGFR cellular distribution and EGFR downstream pathways in pancreatic cancer cells. Oncogene 2011, 30:2514-2525.
    • (2011) Oncogene , vol.30 , pp. 2514-2525
    • Merlin, J.1    Stechly, L.2    de Beaucé, S.3    Monté, D.4    Leteurtre, E.5    van Seuningen, I.6    Huet, G.7    Pigny, P.8
  • 214
    • 79959260943 scopus 로고    scopus 로고
    • Comprehensive analysis of cellular galectin-3 reveals no consistent oncogenic function in pancreatic cancer cells
    • Hann A., Gruner A., Chen Y., Gress T.M., Buchholz M. Comprehensive analysis of cellular galectin-3 reveals no consistent oncogenic function in pancreatic cancer cells. PLoS One 2011, 6:e20859.
    • (2011) PLoS One , vol.6 , pp. e20859
    • Hann, A.1    Gruner, A.2    Chen, Y.3    Gress, T.M.4    Buchholz, M.5
  • 215
    • 84872074052 scopus 로고    scopus 로고
    • Up-regulation of galectin-3 and Sambucus nigra agglutinin binding site is associated with invasion, metastasis and poor-progression of the gallbladder adenocarcinoma
    • Yang L.P., Jiang S., Liu J.Q., Miao X.Y., Yang Z.L. Up-regulation of galectin-3 and Sambucus nigra agglutinin binding site is associated with invasion, metastasis and poor-progression of the gallbladder adenocarcinoma. Hepatogastroenterology 2012, 59:2089-2094.
    • (2012) Hepatogastroenterology , vol.59 , pp. 2089-2094
    • Yang, L.P.1    Jiang, S.2    Liu, J.Q.3    Miao, X.Y.4    Yang, Z.L.5
  • 216
    • 1542292927 scopus 로고    scopus 로고
    • Activation of Galectin-1 gene in human hepatocellular carcinoma involves methylation-sensitive complex formations at the transcriptional upstream and downstream elements
    • Kondoh N., Hada A., Ryo A., Shuda M., Arai M., Matsubara O., Kimura F., Wakatsuki T., Yamamoto M. Activation of Galectin-1 gene in human hepatocellular carcinoma involves methylation-sensitive complex formations at the transcriptional upstream and downstream elements. Int. J. Oncol. 2003, 23:1575-1583.
    • (2003) Int. J. Oncol. , vol.23 , pp. 1575-1583
    • Kondoh, N.1    Hada, A.2    Ryo, A.3    Shuda, M.4    Arai, M.5    Matsubara, O.6    Kimura, F.7    Wakatsuki, T.8    Yamamoto, M.9
  • 218
    • 0032963712 scopus 로고    scopus 로고
    • Galectin-3 expression is induced in cirrhotic liver and hepatocellular carcinoma
    • Hsu D.K., Dowling C.A., Jeng K.C., Chen J.T., Yang R.Y., Liu F.T. Galectin-3 expression is induced in cirrhotic liver and hepatocellular carcinoma. Int. J. Cancer 1999, 81:519-526.
    • (1999) Int. J. Cancer , vol.81 , pp. 519-526
    • Hsu, D.K.1    Dowling, C.A.2    Jeng, K.C.3    Chen, J.T.4    Yang, R.Y.5    Liu, F.T.6
  • 221
    • 38849091469 scopus 로고    scopus 로고
    • Expression of cathepsin D and galectin 3 in tubular carcinomas of the breast
    • Fernandez-Aguilar S., Noël J.C. Expression of cathepsin D and galectin 3 in tubular carcinomas of the breast. APMIS 2008, 116:33-40.
    • (2008) APMIS , vol.116 , pp. 33-40
    • Fernandez-Aguilar, S.1    Noël, J.C.2
  • 224
    • 0037344258 scopus 로고    scopus 로고
    • Galectin-1 accumulation in the ovary carcinoma peritumoral stroma is induced by ovary carcinoma cells and affects both cancer cell proliferation and adhesion to laminin-1 and fibronectin
    • van den BrÛle F., Califice S., Garnier F., Fernandez P.L., Berchuck A., Castronovo V. Galectin-1 accumulation in the ovary carcinoma peritumoral stroma is induced by ovary carcinoma cells and affects both cancer cell proliferation and adhesion to laminin-1 and fibronectin. Lab. Invest. 2003, 83:377-386.
    • (2003) Lab. Invest. , vol.83 , pp. 377-386
    • van den BrÛle, F.1    Califice, S.2    Garnier, F.3    Fernandez, P.L.4    Berchuck, A.5    Castronovo, V.6
  • 225
    • 0028049929 scopus 로고
    • Differential expression of the 67-kD laminin receptor and 31-kD human laminin-binding protein in human ovarian carcinomas
    • van den BrÛle F.A., Berchuck A., Bast R.C., Liu F.T., Gillet C., Sobel M.E., Castronovo V. Differential expression of the 67-kD laminin receptor and 31-kD human laminin-binding protein in human ovarian carcinomas. Eur. J. Cancer 1994, 30A:1096-1099.
    • (1994) Eur. J. Cancer , vol.30 A , pp. 1096-1099
    • van den BrÛle, F.A.1    Berchuck, A.2    Bast, R.C.3    Liu, F.T.4    Gillet, C.5    Sobel, M.E.6    Castronovo, V.7
  • 226
    • 50349096101 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression in serous ovarian carcinoma: an immunohistochemical study with galectin-3 and cyclin D1 and outcome
    • Brustmann H. Epidermal growth factor receptor expression in serous ovarian carcinoma: an immunohistochemical study with galectin-3 and cyclin D1 and outcome. Int. J. Gynecol. Pathol. 2008, 27:380-389.
    • (2008) Int. J. Gynecol. Pathol. , vol.27 , pp. 380-389
    • Brustmann, H.1
  • 229
    • 85027939792 scopus 로고    scopus 로고
    • Investigation of galectin-3 and heparanase in endometrioid and serous carcinomas of the endometrium and correlation with known predictors of survival
    • Ege C.B., Akbulut M., Zekioğlu O., Ozdemir N. Investigation of galectin-3 and heparanase in endometrioid and serous carcinomas of the endometrium and correlation with known predictors of survival. Arch. Gynecol. Obstet. 2011, 284:1231-1239.
    • (2011) Arch. Gynecol. Obstet. , vol.284 , pp. 1231-1239
    • Ege, C.B.1    Akbulut, M.2    Zekioğlu, O.3    Ozdemir, N.4
  • 230
    • 0038173489 scopus 로고    scopus 로고
    • Galectin-3 expression in normal, hyperplastic, and neoplastic endometrial tissues
    • Brustmann H., Riss D., Naudé S. Galectin-3 expression in normal, hyperplastic, and neoplastic endometrial tissues. Pathol. Res. Pract. 2003, 199:151-158.
    • (2003) Pathol. Res. Pract. , vol.199 , pp. 151-158
    • Brustmann, H.1    Riss, D.2    Naudé, S.3
  • 234
    • 0032719687 scopus 로고    scopus 로고
    • Galectin-1 and galectin-3 expression in human prostate tissue and prostate cancer
    • Ellerhorst J., Troncoso P., Xu X.C., Lee J., Lotan R. Galectin-1 and galectin-3 expression in human prostate tissue and prostate cancer. Urol. Res. 1999, 27:362-367.
    • (1999) Urol. Res. , vol.27 , pp. 362-367
    • Ellerhorst, J.1    Troncoso, P.2    Xu, X.C.3    Lee, J.4    Lotan, R.5
  • 235
    • 2242463023 scopus 로고    scopus 로고
    • Galectin-1 expression in prostate tumor-associated capillary endothelial cells is increased by prostate carcinoma cells and modulates heterotypic cell-cell adhesion
    • Clausse N., van den BrÛle F., Waltregny D., Garnier F., Castronovo V. Galectin-1 expression in prostate tumor-associated capillary endothelial cells is increased by prostate carcinoma cells and modulates heterotypic cell-cell adhesion. Angiogenesis 1999, 3:317-325.
    • (1999) Angiogenesis , vol.3 , pp. 317-325
    • Clausse, N.1    van den BrÛle, F.2    Waltregny, D.3    Garnier, F.4    Castronovo, V.5
  • 236
    • 0343962593 scopus 로고    scopus 로고
    • Alteration of the cytoplasmic/nuclear expression pattern of galectin-3 correlates with prostate carcinoma progression
    • van den BrÛle F.A., Waltregny D., Liu F.T., Castronovo V. Alteration of the cytoplasmic/nuclear expression pattern of galectin-3 correlates with prostate carcinoma progression. Int. J. Cancer 2000, 89:361-367.
    • (2000) Int. J. Cancer , vol.89 , pp. 361-367
    • van den BrÛle, F.A.1    Waltregny, D.2    Liu, F.T.3    Castronovo, V.4
  • 237
    • 77951939167 scopus 로고    scopus 로고
    • Evidence of heavy methylation in the galectin 3 promoter in early stages of prostate adenocarcinoma: development and validation of a methylated marker for early diagnosis of prostate cancer
    • Ahmed H., Cappello F., Rodolico V., Vasta G.R. Evidence of heavy methylation in the galectin 3 promoter in early stages of prostate adenocarcinoma: development and validation of a methylated marker for early diagnosis of prostate cancer. Transl. Oncol. 2009, 2:146-156.
    • (2009) Transl. Oncol. , vol.2 , pp. 146-156
    • Ahmed, H.1    Cappello, F.2    Rodolico, V.3    Vasta, G.R.4
  • 241
    • 0029900759 scopus 로고    scopus 로고
    • Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family
    • Su Z.Z., Lin J., Shen R., Fisher P.E., Goldstein N.I., Fisher P.B. Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:7252-7257.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 7252-7257
    • Su, Z.Z.1    Lin, J.2    Shen, R.3    Fisher, P.E.4    Goldstein, N.I.5    Fisher, P.B.6
  • 242
    • 40149087998 scopus 로고    scopus 로고
    • Increased expression and altered intracellular distribution of adhesion/growth-regulatory lectins galectins-1 and -7 during tumour progression in hypopharyngeal and laryngeal squamous cell carcinomas
    • Saussez S., Decaestecker C., Lorfevre F., Chevalier D., Mortuaire G., Kaltner H., André S., Toubeau G., Gabius H.J., Leroy X. Increased expression and altered intracellular distribution of adhesion/growth-regulatory lectins galectins-1 and -7 during tumour progression in hypopharyngeal and laryngeal squamous cell carcinomas. Histopathology 2008, 52:483-493.
    • (2008) Histopathology , vol.52 , pp. 483-493
    • Saussez, S.1    Decaestecker, C.2    Lorfevre, F.3    Chevalier, D.4    Mortuaire, G.5    Kaltner, H.6    André, S.7    Toubeau, G.8    Gabius, H.J.9    Leroy, X.10
  • 245
    • 0033765275 scopus 로고    scopus 로고
    • Adhesive and invasive features in gliomas
    • Tews D.S. Adhesive and invasive features in gliomas. Pathol. Res. Pract. 2000, 196:701-711.
    • (2000) Pathol. Res. Pract. , vol.196 , pp. 701-711
    • Tews, D.S.1
  • 250
    • 79954439197 scopus 로고    scopus 로고
    • Expression of galectin-3, nm-23, and cyclooxygenase-2 could potentially discriminate between benign and malignant pheochromocytoma
    • Saffar H., Sanii S., Heshmat R., Haghpanah V., Larijani B., Rajabiani A., Azimi S., Tavangar S.M. Expression of galectin-3, nm-23, and cyclooxygenase-2 could potentially discriminate between benign and malignant pheochromocytoma. Am. J. Clin. Pathol. 2011, 135:454-460.
    • (2011) Am. J. Clin. Pathol. , vol.135 , pp. 454-460
    • Saffar, H.1    Sanii, S.2    Heshmat, R.3    Haghpanah, V.4    Larijani, B.5    Rajabiani, A.6    Azimi, S.7    Tavangar, S.M.8
  • 252
    • 58249122039 scopus 로고    scopus 로고
    • Increased serum 90K and Galectin-3 expression are associated with advanced stage and a worse prognosis in diffuse large B-cell lymphomas
    • Kim S.J., Lee S.J., Sung H.J., Choi I.K., Choi C.W., Kim B.S., Kim J.S., Yu W., Hwang H.S., Kim I.S. Increased serum 90K and Galectin-3 expression are associated with advanced stage and a worse prognosis in diffuse large B-cell lymphomas. Acta Haematol. 2008, 120:211-216.
    • (2008) Acta Haematol. , vol.120 , pp. 211-216
    • Kim, S.J.1    Lee, S.J.2    Sung, H.J.3    Choi, I.K.4    Choi, C.W.5    Kim, B.S.6    Kim, J.S.7    Yu, W.8    Hwang, H.S.9    Kim, I.S.10
  • 254
    • 77956912887 scopus 로고    scopus 로고
    • Diagnostic significance of CK19, RET, galectin-3 and HBME-1 expression for papillary thyroid carcinoma
    • Zhu X., Sun T., Lu H., Zhou X., Lu Y., Cai X., Zhu X. Diagnostic significance of CK19, RET, galectin-3 and HBME-1 expression for papillary thyroid carcinoma. J. Clin. Pathol. 2010, 63:786-789.
    • (2010) J. Clin. Pathol. , vol.63 , pp. 786-789
    • Zhu, X.1    Sun, T.2    Lu, H.3    Zhou, X.4    Lu, Y.5    Cai, X.6    Zhu, X.7
  • 255
    • 84857920397 scopus 로고    scopus 로고
    • Value of immunohistochemical expression of p27 and galectin-3 in differentiation between follicular adenoma and follicular carcinoma
    • Abulkheir I.L., Mohammad D.B. Value of immunohistochemical expression of p27 and galectin-3 in differentiation between follicular adenoma and follicular carcinoma. Appl. Immunohistochem. Mol. Morphol. 2012, 20:131-140.
    • (2012) Appl. Immunohistochem. Mol. Morphol. , vol.20 , pp. 131-140
    • Abulkheir, I.L.1    Mohammad, D.B.2
  • 259
    • 84860551060 scopus 로고    scopus 로고
    • Tissue and serum galectin-1 expression in patients with colorectal carcinoma
    • Sheng T.H., Rong L.X., Li Z.Y., Bo J., Lei S. Tissue and serum galectin-1 expression in patients with colorectal carcinoma. Hepatogastroenterology 2012, 59:389-394.
    • (2012) Hepatogastroenterology , vol.59 , pp. 389-394
    • Sheng, T.H.1    Rong, L.X.2    Li, Z.Y.3    Bo, J.4    Lei, S.5
  • 260
    • 0027742509 scopus 로고
    • Galaptin and galaptin-binding glycoconjugates in serum and effusions of carcinoma patients
    • Allen H.J., Sharma A., Ahmed H., Piver M.S., Gamarra M. Galaptin and galaptin-binding glycoconjugates in serum and effusions of carcinoma patients. Tumour Biol. 1993, 14:360-368.
    • (1993) Tumour Biol. , vol.14 , pp. 360-368
    • Allen, H.J.1    Sharma, A.2    Ahmed, H.3    Piver, M.S.4    Gamarra, M.5


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